Irun Cohen

Q: What Schools Are Affiliated With Irun Cohen

Irun Cohen is affiliated with the following schools: Weizmann Institute of Science, Tel Aviv University, Royal Postgraduate Medical School, Stanford University, Columbia University

Irun Cohen's AcademicInfluence.com Rankings

Irun Cohen

Biology

#1619

World Rank

#2661

Historical Rank

#787

USA Rank

Immunology

#91

World Rank

#97

Historical Rank

#34

USA Rank

biology Degrees

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Biology

Irun Cohen's Degrees

Doctorate Medicine Stanford University

Why Is Irun Cohen Influential?

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According to Wikipedia, Irun Cohen is an immunologist at the Weizmann Institute of Science, Israel. He moved from the U.S. to Israel in 1968. His contributions to immunology includes, in 1989, the development of the theory of the immunological homunculus, a hypothetical self-image used by the immune system to govern its responses. The bulk of Professor Cohen's work is in the search for treatment for autoimmune disease. Throughout his career he has collaborated with scientists of all nationalities, including the Cuban immunologist Enrique Montero. Cohen is currently the Israeli scientist with the second largest number of publications in the journals of Science and Nature.

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Irun Cohen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis (1981) (941)
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy (1999) (876)
Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis (1988) (865)
Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic protein (1981) (536)
Autoimmunity, microbial immunity and the immunological homunculus. (1991) (518)
β-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial (2001) (485)
Toll-like receptors and their ligands control mesenchymal stem cell functions. (2007) (477)
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. (1990) (474)
Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans. (1985) (453)
Neisseria gonorrhoeae II. Colonial Variation and Pathogenicity During 35 Months In Vitro (1968) (435)
Lines of T lymphocytes induce or vaccinate against autoimmune arthritis. (1983) (434)
Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein. (1991) (415)
Anti-idiotypic network induced by T cell vaccination against experimental autoimmune encephalomyelitis. (1988) (409)
The cognitive paradigm and the immunological homunculus. (1992) (394)
Protective Autoimmunity Is a Physiological Response to CNS Trauma (2001) (349)
Innate and adaptive immune responses can be beneficial for CNS repair (1999) (349)
Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity. (2000) (344)
Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase (1984) (340)
Tending Adam's Garden: Evolving the Cognitive Immune Self (2004) (335)
Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation. (1992) (322)
SYNOVIAL FLUID T CELL REACTIVITY AGAINST 65 kD HEAT SHOCK PROTEIN OF MYCOBACTERIA IN EARLY CHRONIC ARTHRITIS (1988) (311)
T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathies. (2000) (304)
Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II. (1984) (296)
T LYMPHOCYTES OF RHEUMATOID ARTHRITIS PATIENTS SHOW AUGMENTED REACTIVITY TO A FRACTION OF MYCOBACTERIA CROSS-REACTIVE WITH CARTILAGE (1986) (286)
Angiogenesis-Inflammation Cross-Talk: Vascular Endothelial Growth Factor Is Secreted by Activated T Cells and Induces Th1 Polarization (2004) (276)
Design Principles for the Immune System and Other Distributed Autonomous Systems (2001) (273)
Suppressive vaccination with DNA encoding a variable region gene of the T–cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity (1996) (253)
Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells. (1982) (247)
Immune information, self-organization and meaning. (1998) (246)
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis (2008) (235)
Peptide therapy for diabetes in NOD mice (1994) (225)
The cognitive principle challenges clonal selection. (1992) (220)
Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. (2001) (217)
Autoimmune T cells as potential neuroprotective therapy for spinal cord injury (2000) (215)
T lymphocyte line specific for thyroglobulin produces or vaccinates against autoimmune thyroiditis in mice. (1983) (214)
Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. (2007) (213)
T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors (2003) (207)
Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. (2006) (207)
Hsp60 Peptide Therapy of NOD Mouse Diabetes Induces a Th2 Cytokine Burst and Downregulates Autoimmunity to Various β-Cell Antigens (1997) (205)
Polyspecificity of T cell and B cell receptor recognition. (2007) (205)
Autoimmunity can benefit self-maintenance. (2000) (195)
Regulation of Autoimmune Disease Physiological and Therapeutic (1986) (192)
Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins. (1989) (190)
Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells. (1989) (189)
Autoimmunity to chaperonins in the pathogenesis of arthritis and diabetes. (1991) (182)
Heat Shock Proteins as Endogenous Adjuvants in Sterile and Septic Inflammation1 (2005) (181)
Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation. (2003) (173)
Vaccination with Empty Plasmid DNA or CpG Oligonucleotide Inhibits Diabetes in Nonobese Diabetic Mice: Modulation of Spontaneous 60-kDa Heat Shock Protein Autoimmunity1 (2000) (173)
The HSP60 immune system network. (2011) (169)
Effector T lymphocyte line cells migrate to the thymus and persist there (1982) (166)
Autoantibodies to insulin receptor spontaneously develop as anti-idiotypes in mice immunized with insulin. (1982) (164)
Functional immunomics: Microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes (2004) (162)
Differential T cell response in central and peripheral nerve injury: connection with immune privilege (1999) (159)
T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis. (1985) (158)
T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity (2014) (156)
Inhibition of T lymphocyte heparanase by heparin prevents T cell migration and T cell‐mediated immunity (1990) (154)
Stress, Heat Shock Proteins, and Autoimmunity (2007) (145)
Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species. (1987) (143)
T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides. (1999) (141)
Natural autoantibodies might prevent autoimmune disease. (1986) (140)
Explaining a complex living system: dynamics, multi-scaling and emergence (2007) (138)
T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells (1983) (138)
Biomarkers, self-antigens and the immunological homunculus. (2007) (135)
Enhancing T lymphocytes from tumor‐bearing mice suppress host resistance to a syngeneic tumor (1974) (133)
Therapeutic vaccination against adjuvant arthritis using autoimmune T cells treated with hydrostatic pressure. (1987) (129)
A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model. (1996) (128)
IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2. (1996) (123)
Specificity of T lymphocyte lines for peptides of myelin basic protein. (1985) (122)
Discrimination and dialogue in the immune system. (2000) (120)
The immune system as a reactive system: modeling T cell activation with statecharts (2001) (120)
Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies. (2004) (119)
Real and artificial immune systems: computing the state of the body (2007) (118)
Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: suppressed EAE effector T cells recovered as T cell lines. (1982) (118)
Treatment of new‐onset type 1 diabetes with peptide DiaPep277® is safe and associated with preserved beta‐cell function: extension of a randomized, double‐blind, phase II trial (2007) (115)
Inhibition of Adjuvant Arthritis by a DNA Vaccine Encoding Human Heat Shock Protein 601 (2002) (115)
Treatment of Autoimmune Diabetes and Insulitis in NOD Mice With Heat Shock Protein 60 Peptide p277 (1995) (114)
Cutting Edge: T Cells Respond to Lipopolysaccharide Innately via TLR4 Signaling1 (2007) (111)
Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants (2010) (111)
Autoimmune Diabetes Induced by the β-cell Toxin STZ: Immunity to the 60-kDa Heat Shock Protein and to Insulin (1994) (109)
Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor alpha secretion. (1994) (108)
Soluble antigen induces T lymphocytes to secrete an endoglycosidase that degrades the heparan sulfate moiety of subendothelial extracellular matrix (1987) (106)
Vaccination against autoimmune encephalomyelitis (EAE): Attenuated autoimmune T lymphocytes confer resistance to induction of active EAE but not to EAE mediated by the intact T lymphocyte line (1981) (103)
Regulation of autosensitization. The immune activation and specific inhibition of self-recognizing thymus-derived lymphocytes. (1973) (102)
The immune-body cytokine network defines a social architecture of cell interactions (2006) (99)
DNA Fragments of the Human 60-kDa Heat Shock Protein (HSP60) Vaccinate Against Adjuvant Arthritis: Identification of a Regulatory HSP60 Peptide 1 (2003) (97)
Reactive animation: realistic modeling of complex dynamic systems (2005) (97)
NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells. (1996) (97)
The self, the world and autoimmunity. (1988) (95)
Thymus-Derived Lymphocytes: Humoral and Cellular Reactions Distinguished by Hydrocortisone (1972) (95)
Accumulation of passively transferred primed T cells independently of their antigen specificity following central nervous system trauma (1998) (95)
T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences (2017) (94)
Autoimmune T cells retard the loss of function in injured rat optic nerves (2000) (94)
A cartilage-mimicking T-cell epitope on a 65K mycobacterial heat-shock protein: adjuvant arthritis as a model for human rheumatoid arthritis. (1989) (94)
Tregs in T cell vaccination: exploring the regulation of regulation. (2004) (93)
AUTOSENSITIZATION IN VITRO (1971) (92)
Heat Shock Protein 60 Activates B Cells via the TLR4-MyD88 Pathway1 (2005) (92)
Emergent Dynamics of Thymocyte Development and Lineage Determination (2006) (91)
Autoantibodies to the insulin receptor in juvenile onset insulin-dependent diabetes (1983) (91)
Therapy with the hsp60 peptide DiaPep277™ in C‐peptide positive type 1 diabetes patients (2007) (90)
Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data (2009) (88)
Low-dose low-molecular-weight heparin (enoxaparin) is beneficial in lichen planus: a preliminary report. (1998) (86)
Infection and Autoimmunity (1987) (86)
Competition between, and effectiveness of, IgG and IgM antibodies in indirect fluorescent antibody and other tests. (1967) (85)
Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7. (1997) (85)
Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein. (2004) (83)
The Immune System Computes the State of the Body: Crowd Wisdom, Machine Learning, and Immune Cell Reference Repertoires Help Manage Inflammation (2019) (81)
Four-dimensional realistic modeling of pancreatic organogenesis (2008) (79)
The 60-kDa heat shock protein modulates allograft rejection. (1999) (77)
Modulation of proteinase‐K resistant prion protein by prion peptide immunization (2001) (77)
Autoimmune maintenance and neuroprotection of the central nervous system (1999) (77)
T-cell vaccination. (1988) (77)
Induction of diabetes in standard mice by immunization with the p277 peptide of a 60‐kDa heat shock protein (1995) (76)
The remedy may lie in ourselves: prospects for immune cell therapy in central nervous system protection and repair (1999) (76)
Ectopic PDX-1 expression in liver ameliorates type 1 diabetes. (2007) (75)
Experimental autoimmune hepatitis: disease induction, time course and T-cell reactivity. (1990) (75)
Antigen microarrays identify CNS-produced autoantibodies in RRMS (2012) (75)
Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies. (1997) (74)
Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: genotype of antigen-presenting cells influences immunodominant epitope of basic protein. (1986) (73)
Immunospecific inhibition of nerve conduction by T lymphocytes reactive to basic protein of myelin (1983) (72)
An antibody profile of systemic lupus erythematosus detected by antigen microarray (2010) (72)
Immunotherapy of lethal metastases by lymphocytes sensitized against tumor cells in vitro. (1975) (72)
Identification of alpha‐tropomyosin as a target self‐antigen in Behçet's syndrome (2002) (71)
Vaccination against autoimmune disease with lines of autoimmune T lymphocytes. (1983) (71)
T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins. (1992) (71)
Heat Shock Protein 60 Inhibits Th1-Mediated Hepatitis Model via Innate Regulation of Th1/Th2 Transcription Factors and Cytokines1 (2005) (70)
DNA Vaccination with Heat Shock Protein 60 Inhibits Cyclophosphamide-Accelerated Diabetes1 (2002) (70)
On Tending Adam's Garden (2000) (70)
Shifts in the epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis. (1993) (68)
T cells and autoantibodies to human HSP70 in type 1 diabetes in children. (2003) (68)
Experimental autoimmune hepatitis: Disease induction, time course and t‐cell reactivity (1990) (66)
Idiotypic immunization induces immunity to mutated p53 and tumor rejection (1998) (66)
HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation. (2005) (64)
A disaccharide that inhibits tumor necrosis factor alpha is formed from the extracellular matrix by the enzyme heparanase. (1995) (63)
The natural autoantibody repertoire and autoimmune disease. (2004) (63)
Autoimmune disease models : a guidebook (1994) (62)
Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals (2013) (62)
Autoimmune Encephalomyelitis: Activation of Thymus Lymphocytes against Syngeneic Brain Antigens in vitro (1974) (62)
Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer. (2011) (62)
Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of myelin basic protein. Vaccination is determinant specific. (1983) (61)
Glucocorticoids and cellular immunity in vitro. Facilitation of the sensitization phase and inhibition of the effector phase of a lymphocyte anti-fibroblast reaction. (1970) (61)
The hsp60 Peptide p277 Arrests the Autoimmune Diabetes Induced by the Toxin Streptozotocin (1996) (61)
Antibodies to mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma). (1992) (59)
Binding of anti-DNA antibodies and inhibition of glomerulonephritis in MRL-lpr/lpr mice by heparin. (1990) (59)
Theories of Immune Networks (1989) (57)
Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity. (2003) (57)
Autoimmunity to the p53 protein is a feature of systemic lupus erythematosus (SLE) related to anti-DNA antibodies. (2001) (56)
Heparin disaccharides inhibit tumor necrosis factor-alpha production by macrophages and arrest immune inflammation in rodents. (1997) (55)
The lysis of fibroblasts by lymphocytes sensitized in vitro: specific antigen activates a nonspecific effect. (1970) (54)
Heat Shock Protein 60 Activates Cytokine-Associated Negative Regulator Suppressor of Cytokine Signaling 3 in T Cells: Effects on Signaling, Chemotaxis, and Inflammation1 (2005) (54)
Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. I. Characterization of the antibodies. (1984) (53)
Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling. (2018) (52)
Autosensitization of Lymphocytes against Thymus Reticulum Cells (1972) (52)
Mutation at H–2K locus influences susceptibility to autoimmune thyroiditis (1979) (52)
In vitro cytotoxicity and in vivo tumor enhancement induced by mouse spleen cells autosensitized in vitro (1973) (51)
Network regulation of autoimmunity: an automation model. (1989) (51)
Activation of benign autoimmunity as both tumor and autoimmune disease immunotherapy: a comprehensive review. (2014) (50)
Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial (2014) (50)
The pathogenicity of islet‐infiltrating lymphocytes in the non‐obese diabetic (NOD) mouse (1999) (50)
Do all creatures possess an acquired immune system of some sort? (2014) (49)
The peptide-binding strategy of the MHC class II I-A molecules. (1998) (49)
Antibodies to Insulin Receptor Followed by Anti-Idiotype: Antibodies to Insulin in Child With Hypoglycemia (1987) (49)
Spontaneous remission of autoimmune encephalomyelitis is inhibited by splenectomy, thymectomy or ageing (1980) (49)
T-cell vaccination for autoimmune disease: a panorama. (2001) (48)
Expression of major histocompatibility complex class II molecules in rat T cells (1994) (48)
T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis (1984) (48)
Antigen-receptor degeneracy and immunological paradigms. (2004) (47)
The peptide binding specificity of the MHC class II I-A molecule of the Lewis rat, RT1.BI. (1996) (47)
Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice (2003) (46)
Vaccination against experimental autoimmune encephalomyelitis using a subencephalitogenic dose of autoimmune effector T cells. (2). Induction of a protective anti-idiotypic response. (1989) (45)
The Lymph Node B Cell Immune Response: Dynamic Analysis In-Silico (2008) (45)
Acceleration of autoimmune diabetes by cyclophosphamide is associated with an enhanced IFN-gamma secretion pathway. (1999) (45)
Autoantibody repertoires, natural biomarkers, and system controllers. (2013) (45)
Sensitization of T lymphocytes in vitro by syngeneic macrophages fed with tumor antigens. (1976) (44)
Suppression of experimental autoimmune encephalomyelitis by intravenously administered polyclonal immunoglobulins. (2000) (44)
DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response. (2004) (44)
Autoimmune Encephalomyelitis and Uveitis Induced by T Cell Immunity to Self β-Synuclein1 (2003) (44)
Network Theory Analysis of Antibody-Antigen Reactivity Data: The Immune Trees at Birth and Adulthood (2011) (44)
Islet T Cells Secreting IFN-γ in NOD Mouse Diabetes: Arrest by p277 Peptide Treatment (1998) (44)
T lymphocytes with promiscuous cytotoxicity (1976) (44)
Regulation of NOD mouse autoimmune diabetes by T cells that recognize a TCR CDR3 peptide. (1999) (44)
IL-2 and TNF receptors as targets of regulatory T-T interactions: isolation and characterization of cytokine receptor-reactive T cell lines in the Lewis rat. (1996) (43)
HSP60 as a Target of Anti-Ergotypic Regulatory T Cells (2008) (43)
T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients. (2004) (43)
Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis. (2006) (43)
T‐Cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif (2007) (42)
T cell immunity to myelin basic protein induces anterior uveitis in Lewis rats (1994) (42)
Experimental autoimmune encephalomyelitis (EAE) in genetically resistant rats: PVG rats resist active induction of EAE but are susceptible to and can generate EAE effector T cell lines. (1982) (42)
Modeling complexity in biology (2001) (42)
Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice. (2001) (42)
Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer’s disease in bladder cancer patients (2019) (42)
Genetic control of autoimmune encephalomyelitis and recognition of the critical nonapeptide moiety of myelin basic protein in guinea pigs are exerted through interaction of lymphocytes and macrophages (1981) (42)
Alpha tropomyosin as a self‐antigen in patients with Behçet's disease (2005) (42)
A quantitative model of autoimmune disease and T-cell vaccination: does more mean less? (1995) (42)
Pathogenicity of T cells responsive to diverse cryptic epitopes of myelin basic protein in the Lewis rat. (1995) (42)
T Cell Vaccination Benefits Relapsing Progressive Multiple Sclerosis Patients: A Randomized, Double-Blind Clinical Trial (2012) (41)
Suppressor factor secreted by T-lymphocytes from tumor-bearing mice. (1976) (41)
Epstein–Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti‐DNA (2014) (41)
Identification of Aldolase as a Target Antigen in Alzheimer’s Disease (2005) (41)
Anti-inflammatory effects of heparin and its derivatives: inhibition of complement and of lymphocyte migration. (1992) (41)
Amendment history : Retraction ( May 2018 ) Heat shock protein 60 enhances CD 4 + CD 25 + regulatory T cell function via innate TLR 2 signaling (2006) (40)
Vaccination against experimental autoimmune encephalomyelitis using a subencephalitogenic dose of autoimmune effector cells (1). Characteristics of vaccination. (1989) (40)
Antigenic mimicry between mycobacteria and cartilage proteoglycans: the model of adjuvant arthritis. (1987) (40)
D‐enantiomer peptide of the TCRa transmembrane domain inhibits T‐cell activation in vitro and in vivo (2005) (40)
Antigenic mimicry, clonal selection and autoimmunity. (2001) (40)
Gut feelings of safety: tolerance to the microbiota mediated by innate immune receptors (2015) (40)
INDUCTION OF T‐CELL DIFFERENTIATION IN VITRO BY THYMUS EPITHELIAL CELLS * (1975) (40)
Clinical modeling of T cell vaccination against autoimmune diseases in rats. Selection of antigen-specific T cells using a mitogen. (1990) (40)
Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65-kDa heat shock protein, to its 180-188 peptide, and to a partially homologous peptide of the proteoglycan link protein. (1992) (39)
A Systems Immunology Approach to the Host-Tumor Interaction: Large-Scale Patterns of Natural Autoantibodies Distinguish Healthy and Tumor-Bearing Mice (2009) (39)
The Cell‐Mediated Immune Response: Interactions of Initiator and Recruited T Lymphocytes (1976) (38)
Lymphocyte receptors for autoantigens, autologous serum inhibits self-recognition. (1973) (38)
Self and foreign 60-kilodalton heat shock protein T cell epitope peptides serve as immunogenic carriers for a T cell-independent sugar antigen. (1995) (38)
Natural and Immune Human Antibodies Reactive with Antigens of Virulent Neisseria gonorrhoeae: Immunoglobulins G, M, and A (1967) (37)
Effects of inoculation with attenuated autologous T cells in patients with rheumatoid arthritis. (1993) (37)
Biochemical characterization of the human diabetes‐associated HLA‐DQ8 allelic product: Similarity to the major histocompatibility complex class II I‐Ag7 protein of non‐obese diabetic mice (1997) (37)
Proliferation and competition in discrete biological systems (2003) (37)
Extracellular matrix induces tumour necrosis factor-alpha secretion by an interaction between resting rat CD4+ T cells and macrophages. (1993) (37)
REJECTION OF TUMOR ALLOGRAFTS BY MOUSE SPLEEN CELLS SENSITIZED IN VITRO (1971) (37)
Antibodies of the IgG, IgM, and IgA classes in newborn and adult sera reactive with gram-negative bacteria (1968) (37)
Immune system computation and the immunological homunculus (2006) (36)
NAP, a Peptide Derived from the Activity‐Dependent Neuroprotective Protein, Modulates Macrophage Function (2006) (36)
The natural autoantibody repertoire in newborns and adults: a current overview. (2012) (36)
Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. II. Effects on glucose homeostasis and the insulin receptor. (1984) (36)
H‐2 genetic control of the response of T lymphocytes to insulins. Priming of nonresponder mice by forbidden variants of specific antigenic determinants (1980) (35)
The recruitment of specific effector lymphocytes by antigen-reactive lymphocytes in cell-mediated autosensitization and allosensitization reactions. (1973) (35)
Low doses of low molecular weight heparin in vivo inhibits the elicitation of contact hypersensitivity. (1994) (33)
Induction of IgG3 to LPS via Toll-Like Receptor 4 Co-Stimulation (2008) (33)
Normal T-cell receptors for alloantigens. (1973) (33)
Vaccination against Experimental Autoimmune Diseases Using T Lymphocytes Treated with Hydrostatic Pressure (1986) (32)
Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies (2010) (32)
HIV-1 gp41 and TCRα Trans-Membrane Domains Share a Motif Exploited by the HIV Virus to Modulate T-Cell Proliferation (2010) (32)
Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection. (1999) (32)
Heparin‐disaccharide affects T cells: inhibition of NF‐κB activation, cell migration, and modulation of intracellular signaling (2004) (31)
Natural Id-Anti-Id Networks and the Immunological Homunculus (1989) (31)
Induction of the anti-ergotypic response. (1993) (31)
Multiple sclerosis-like disease induced in rabbits by immunization with brain gangliosides. (1981) (31)
Systemic lupus erythematosus in mice, spontaneous and induced, is associated with autoimmunity to the C‐terminal domain of p53 that recognizes damaged DNA (2000) (30)
Anti‐ergotypic Immunoregulation (2006) (30)
Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood. (2011) (30)
A cellulose-binding domain-fused recombinant human T cell connective tissue-activating peptide-III manifests heparanase activity. (1999) (30)
Autoimmunization to epidermal growth factor, a component of the immunological homunculus. (2002) (30)
A syngeneic metastatic tumor model in mice: the natural immune response of the host and its manipulation. (1976) (29)
Regulation of autosensitisation to encephalitogenic myelin basic protein by macrophage-associated and soluble antigen (1977) (28)
Recruitment of effector T lymphocytes against a tumor allograft by T lymphocytes sensitized in vitro. (1973) (28)
Reactive Animation (2002) (28)
Pneumococcal Capsular Polysaccharide Is Immunogenic When Present on the Surface of Macrophages and Dendritic Cells: TLR4 Signaling Induced by a Conjugate Vaccine or by Lipopolysaccharide Is Conducive1 (2008) (28)
Islet T cells secreting IFN-gamma in NOD mouse diabetes: arrest by p277 peptide treatment. (1998) (28)
H‐2 gene products influence susceptibility of target thyroid gland to damage in experimental autoimmune thyroiditis (1980) (28)
Sequential interaction of macrophages, initiator T lymphocytes and recruited T lymphocytes in a cell‐mediated immune response to soluble antigen (1978) (28)
Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies. (2004) (28)
Activation of p53 protein by telomeric (TTAGGG)n repeats. (2001) (28)
Informational Landscapes in Art, Science, and Evolution (2006) (27)
Physiological basis of T-cell vaccination against autoimmune disease. (1989) (27)
Simplicity belies a complex system: a response to the minimal model of immunity of Langman and Cohn. (2002) (27)
A theoretical analysis of the phenotypic expression of immune response genes (1980) (27)
Histopathology of arthritis induced in rats by active immunization to mycobacterial antigens or by systemic transfer of T lymphocyte lines. A light and electron microscopic study of the articular surface using cationized ferritin. (1987) (27)
Heparan sulfate degradation in tumor cell invasion and angiogenesis. (1988) (26)
Heat Shock Protein 60, via MyD88 Innate Signaling, Protects B Cells from Apoptosis, Spontaneous and Induced1 (2009) (26)
Intravenous gammaglobulin treatment in multiple sclerosis and experimental autoimmune encephalomyelitis: delineation of usage and mode of action. (1994) (26)
The Th1/Th2 dichotomy, hsp60 autoimmunity, and type I diabetes. (1997) (25)
Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis. (2001) (25)
Disaccharides derived from heparin or heparan sulfate regulate IL-8 and IL-1 beta secretion by intestinal epithelial cells. (2001) (25)
Immune response genes have a variable influence on the selection of antigenic foreign and self determinants of insulin. (1979) (25)
Production and Purification of a Recombinant Human hsp60 Epitope Using the Cellulose-Binding Domain inEscherichia coli (1998) (24)
Inhibition of diabetes in NOD mice by idiotypic induction of SLE. (1999) (24)
Treatment of autoimmune disease: to activate or to deactivate? (1995) (24)
Proteins and Their Derived Peptides as Carriers in a Conjugate Vaccine for Streptococcus pneumoniae: Self-Heat Shock Protein 60 and Tetanus Toxoid1 (2003) (24)
The effect of hydrocortisone on lymphocyte-mediated cytolysis. (1973) (24)
Genetics as Explanation: Limits to the Human Genome Project (2009) (24)
T‐Cell Mediated Immunity in Vitro: an Analysis of Antigen Recognition and Target Cell Lysis (1972) (24)
Tumor-Associated and Disease-Associated Autoantibody Repertoires in Healthy Colostrum and Maternal and Newborn Cord Sera (2015) (24)
Serum antibody response in experimental human gonorrhoea. Immunoglobulins G, A, and M. (1969) (23)
Modeling biological reactivity: statecharts vs. Boolean logic (2002) (23)
GemCell: A generic platform for modeling multi-cellular biological systems (2008) (23)
A Structurally Altered d,l-Amino Acid TCRα Transmembrane Peptide Interacts with the TCRα and Inhibits T-Cell Activation in Vitro and in an Animal Model† (2007) (22)
Kadishman's tree, Escher's angels, and the immunological homunculus. (1996) (22)
The mycobacterial 65 kD heat-shock protein and autoimmune arthritis (2004) (22)
Activation of specific T cell lines by the antigens avidin and myelin basic protein in the absence of antigen‐presenting cells (1987) (22)
Regulatory T Cells in Autoimmune Diseases: Anti-Ergotypic T Cells (2005) (22)
Modeling immune behavior for experimentalists (2007) (22)
T-cell autoimmunity in type 1 diabetes mellitus. (1993) (22)
STIMULATION OF RAT LYMPHOCYTE PROLIFERATION BY HYDROCORTISONE DURING THE INDUCTION OF CELL-MEDIATED IMMUNITY IN VITRO (1974) (21)
H-2K mutation controls immune response phenotype of autoimmune thyroiditis. Critical expression of mutant gene product in both thymus and thyroid glands (1980) (21)
Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin (2013) (21)
Abnormalities in brain myelin of rabbits with experimental autoimmune multiple sclerosis‐like disease induced by immunization to gangliosides (1982) (21)
Role of the thymus in induction and transfer of vaccination against adjuvant arthritis with a T lymphocyte line in rats. (1985) (21)
Lymphoid cells sensitized in vitro against allogeneic or syngeneic fibroblasts produce immune effects in vitro and in vivo. (1971) (21)
IL-10 Mediates Resistance to Adoptive Transfer Experimental Autoimmune Encephalomyelitis in MyD88−/− Mice (2009) (21)
SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®). (2016) (20)
Diversity of the B cell repertoire to myelin basic protein in rat strains susceptible and resistant to EAE. (1999) (20)
Genome instability in cancer development (2005) (20)
Can immunization with Bacillus Calmette-Guérin (BCG) protect against Alzheimer's disease? (2019) (20)
Cell-mediated autoimmunity: antigen reactive lymphocytes recruit specific effector lymphocytes. (1973) (20)
TRANSITION FROM T CELL PROTECTION TO T CELL ENHANCEMENT DURING TUMOR GROWTH IN AN ALLOGENEIC HOST (1976) (20)
Peptide binding motifs of the MHC class I molecules (RT1.Al) of the Lewis rat (1997) (20)
The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice (2005) (19)
Split Immunity: Immune Inhibition of Rat Gliomas by Subcutaneous Exposure to Unmodified Live Tumor Cells (2011) (19)
Systemic features of immune recognition in the gut. (2011) (19)
Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma (2015) (19)
Anti-ergotypic T cells in naïve rats. (2005) (19)
Individual and meta-immune networks (2013) (18)
Amyloid beta-HSP60 peptide conjugate vaccine treats a mouse model of Alzheimer's disease. (2011) (18)
DNA vaccines coding for heat-shock proteins (HSPs): tools for the activation of HSP-specific regulatory T cells (2005) (18)
Immunity to p53 induced by an idiotypic network of anti-p53 antibodies: generation of sequence-specific anti-DNA antibodies and protection from tumor metastasis. (1998) (18)
A conjugate vaccine composed of a heat shock protein 60 T-cell epitope peptide (p458) and Neisseria meningitidis type B capsular polysaccharide. (2006) (18)
Prolongation of survival of rat cardiac allografts by T cell vaccination. (1993) (18)
Regulatory T cells and immune computation (2008) (17)
A shared TCR CDR3 sequence in NOD mouse autoimmune diabetes. (1999) (17)
Concurrency in Biological Modeling: Behavior, Execution and Visualization (2007) (17)
Prevalence of Autoantibodies to the p53 Protein in Autoimmune Hepatitis (2002) (17)
Monoclonal antibody to a DNA‐binding domain of p53 mimics charge structure of DNA: anti‐idiotypes to the anti‐p53 antibody are anti‐DNA (2004) (17)
Heterogeneity in the development of cytotoxic T lymphocytes in vitro revealed by sensitivity to hydrocortisone (1975) (16)
T Cell Vaccination and Suppression of Autoimmune Disease (1989) (16)
The heuristics of biologic theory: the case of self-nonself discrimination. (2003) (16)
Prolongation of rat skin and cardiac allograft survival by low molecular weight heparin. (1999) (16)
HSP60 speaks to the immune system in many voices. (2008) (16)
Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor. (2008) (16)
Autoimmunity to hsp65 and the immunologic paradigm. (1992) (16)
Updating Darwin: Information and entropy drive the evolution of life (2016) (16)
Mechanisms of resistance to autoimmune disease induced by T-cell vaccination. (1991) (15)
G-CSF enhances the adhesion of encephalitogenic T cells to extracellular matrix components: A possible mechanism for exacerbation of multiple sclerosis (2006) (15)
Low-dose heparin inhibits acute graft versus host disease in mice. (1993) (14)
Recruitment of effector lymphocytes by initiator lymphocytes. Circulating lymphocytes are trapped in the reacting lymph node. (1976) (14)
Inserted H–2 gene membrane products mediate immune response phenotype of antigen-presenting cell (1981) (14)
DiaPep277® and immune intervention for treatment of type 1 diabetes. (2013) (14)
Modeling the influence of TH1- and TH2-type cells in autoimmune diseases. (2000) (14)
Chimeric vaccine composed of viral peptide and mammalian heat‐shock protein 60 peptide protects against West Nile virus challenge (2010) (14)
A heat shock protein, molecular mimicry and autoimmunity. (1990) (14)
Lymph node cell vaccination against the lupus syndrome of MRL/lpr/lpr mice (1996) (14)
Self prion protein peptides are immunogenic in Lewis rats. (2001) (14)
T-cell vaccination against anti-CD4 autoimmunity in HIV-1 infected patients. (2004) (13)
Experimental autoimmune myasthenia gravis in naive non-obese diabetic (NOD/LtJ) mice: susceptibility associated with natural IgG antibodies to the acetylcholine receptor. (2003) (13)
Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal (2014) (13)
Histochemical studies of progressive p53 mutations during colonic carcinogenesis in Sprague-Dawley rats induced by N-methyl-N-nitro-nitrosoguanidine or azoxymethane. (1994) (13)
Recruitment of effector lymphocytes by initiator lymphocytes. Recruited lymphocytes are immunospecific and include graft-versus-host-reactive lymphocytes. (1976) (13)
The dominant and the cryptic T cell repertoire to myelin basic protein in the Lewis rat (1996) (13)
NATURAL RESISTANCE OF GERM-FREE MICE AND COLOSTRUM-DEPRIVED PIGLETS TO GROUP A STREPTOCOCCI. (1965) (13)
T cells in the spinal cord in experimental autoimmune encephalomyelitis are matrix adherent and secrete tumor necrosis factor alpha (1992) (13)
Crystal‐ball gazing − the future of immunological research viewed from the cutting edge (2006) (13)
Disaccharides generated from heparan sulphate or heparin modulate chemokine-induced T-cell adhesion to extracellular matrix. (2000) (13)
Parasite immunology and lymphocyte population dynamics. (1986) (12)
Molecular Chaperones and Cell Signalling: Heat Shock Proteins Regulate Inflammation by Both Molecular and Network Cross-Reactivity (2005) (12)
Insulin-Mimicking Anti-Idiotypic Antibodies in Development of Spontaneous Autoimmune Diabetes in BB/E Rats (1990) (12)
Mice immunized to insulin develop antibody to the insulin receptor (1983) (12)
Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland. (2005) (12)
Vaccines to Treat Drug Addiction (2004) (12)
Exploring the potential of DNA vaccination. (1997) (12)
The advantage of being a low responder. (1985) (12)
Therapy with the hsp 60 peptide DiaPep 277 TM in C-peptide positive type 1 diabetes patients (2007) (12)
A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model. (2007) (12)
Genetic control of experimental autoimmune encephalomyelitis at the level of cytotoxic lymphocytes in guinea pigs (1982) (11)
Integrative analysis correlates donor transcripts to recipient autoantibodies in primary graft dysfunction after lung transplantation (2011) (11)
Innovative Immune-Based Therapeutic Approaches for the Treatment of Type 1 Diabetes Mellitus (2005) (11)
Experimental autoimmune keratitis induced in rats by anti-cornea T-cell lines. (1999) (10)
Resistance to Experimental Autoimmunity Using T Lymphocyte Vaccines (1986) (10)
Mouse Dendritic Cells Pulsed with Capsular Polysaccharide Induce Resistance to Lethal Pneumococcal Challenge: Roles of T Cells and B Cells (2012) (10)
T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells. (2010) (10)
Reactive animation: From piecemeal experimentation to reactive biological systems (2011) (10)
The study and manipulation of experimental autoimmune disease using T lymphocyte lines. (1985) (10)
Monoclonal antibodies to insulin and to the insulin receptor (anti-ID) modify the morphologies of insulin crystals (1992) (9)
Human neonatal thymectomy induces altered B‐cell responses and autoreactivity (2017) (9)
17 A theory for complex systems: reactive animation (2005) (9)
A modified technique for experimental skin grafting. (1986) (9)
How special is a pathogenic CNS autoantigen? Immunization to many CNS self-antigens does not induce autoimmune disease (2006) (9)
T-cell vaccination against anti-CD4 autoimmunity in HIV-1 subtypes B and C-infected patients--an extended open trial. (2005) (9)
Elevated Cellular Immune Response to Human Heat-Shock Protein-60 in Schizophrenic Patients (1999) (9)
A Human Monoclonal Antibody to Insulin (1986) (9)
Stable Changes in Mesenchymal Stromal Cells from Multiple Myeloma Patients Revealed through Their Responses to Toll-Like Receptor Ligands and Epidermal Growth Factor (2012) (9)
The Emergence of Spatial Complexity in the immune System (2000) (8)
Production and purification of a recombinant human hsp60 epitope using the cellulose-binding domain in Escherichia coli. (1998) (8)
Antigenic mimicry between mycobacteria and cartilage proteoglycans (1987) (8)
The SLE-key test serological signature: new insights into the course of lupus (2018) (8)
Chapter 20 – Immunization to Insulin Generates Antiidiotypes That Behave as Antibodies to the Insulin Hormone Receptor and Cause Diabetes Mellitus (1984) (8)
On the regulation of EAE. (1993) (8)
Inhibition of the mixed lymphocyte reaction by T cell vaccination (1990) (8)
The induction of a cellular immune reaction against self-antigens present in the thymus. (1973) (8)
Vaccines to prevent and treat autoimmune diseases. (1995) (8)
Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists. (1988) (7)
The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction. (2020) (7)
Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insulin Receptor (1988) (7)
Questions about NOD mouse diabetes. (1997) (7)
T lymphocyte line-mediated experimental allergic encephalomyelitis--a pharmacologic model for testing of immunosuppressive agents for the treatment of autoimmune central nervous system disease. (1987) (7)
Activation of the Akt–CREB signalling axis by a proline‐rich heptapeptide confers resistance to stress‐induced cell death and inflammation (2017) (7)
HSP60 and the regulation of inflammation: Physiological and pathological (2003) (7)
Adjuvant arthritis is associated with changes in the glycosylation of serum IgGl and IgG2b (1993) (7)
Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice (2017) (7)
GLUCOCORTICOIDS AND CELLULAR IMMUNITY IN VITRO (1970) (7)
Crossreactivity of anti-DNA antibodies. (1990) (7)
Increased Incidence of Urethane Induced Lung Adenomata by Autosensitized Lymphocytes (1974) (6)
Propagation of lewis rat encephalitogenic T cell lines: T-cell-growth-factor is superior to recombinant IL-2 (2002) (6)
REGULATION OF AUTOSENSITIZATION (1973) (6)
Antibiodies of the IgG, IgM, and IgA classes in newborn and adult sera reactive with gram-negative bacteria. (1968) (6)
Immunological expression of gangliosides in multiple sclerosis and in a demyelinating model disease in rabbits. (1984) (6)
Selection of anti-myelin basic protein T-cell lines in the Lewis rat: V-β 8.2 dominance and conserved complementarity-determining-region-3 motifs are dependent on serine at position 78 of myelin basic protein (2000) (6)
Updates on Clostridium difficile in Europe (2018) (6)
Tolerance to experimental contact sensitivity induced by T cell vaccination (1990) (6)
Executable Modeling of Morphogenesis: A Turing-Inspired Approach (2012) (6)
Recruitment of effector lymphocytes by initiator lymphocytes. In vivo migration of in vitro sensitized initiator T lymphocytes (1975) (6)
Natural occurrence of thymocytes that react with myelin basic protein (1980) (6)
Immunoglobulin Class of Natural Human Antibodies Reactive with Treponema pallidum (1970) (6)
Autoimmune T-lymphocytes with specificity for pancreatic islet antigens. (1985) (6)
Principles of Molecular Mimicry and Autoimmune Disease (2000) (6)
Unique Gene Expression Patterns in Human T-cell Lines Generated from Multiple Sclerosis Patients by Stimulation with a Synthetic MOG Peptide (2005) (6)
Forum: How Complexity Helps to Shape Alloimmunity (2001) (6)
T-cell vaccination against autoimmune disease. (1989) (6)
Physiology and pathophysiology of autoimmunity. (1991) (6)
Effect of treatment with the methanol extraction residue fraction of killed tubercle bacilli (MER) on the development of spontaneous pulmonary metastases from syngeneic implants of tumor 3LL in C57B1 mice. (1976) (5)
Advances in Cancer Biomarkers (2015) (5)
Thoughts on the pathogenesis of type 1 diabetes and on the arrest of autoimmune beta-cell destruction by peptide p277 vaccination. (2004) (5)
HSP 60 as a Target of Anti-Ergotypic Regulatory T Cells (2008) (5)
DNA Vaccination With Hsp70 Protects Against Systemic Lupus Erythematosus in (NZB × NZW)F1 Mice (2020) (5)
T-Cell Vaccination for HIV-Seropositive Patients (1996) (5)
Autoimmunity and The Host-Parasite Relationship (1986) (5)
T‐cell seeding: neonatal transfer of anti‐myelin basic protein T‐cell lines renders Fischer rats susceptible later in life to the active induction of experimental autoimmune encephalitis (2009) (5)
Polyglutamine Disorders (2018) (5)
Experimental animal skin grafting simplified. (1982) (5)
Language, meaning and the immune system. (1995) (5)
An eclectic summary of the symposium on autoimmunity. (1989) (5)
Rain and Resurrection How the Talmud and Science Read the World (2010) (5)
Treatment of Recent-Onset Type 1 Diabetic Patients With DiaPep277: Results of a Double-Blind, Placebo-Controlled, Randomized Phase 3 Trial. Diabetes Care 2014;37:1392–1400. DOI: 10.2337/dc13-1391 (2014) (5)
Immunity to 60 kDa heat shock protein in autoimmune diabetes (1996) (5)
Autoimmune thyroiditis (EAT) in genetically resistant mice mediated by a T cell line. (1992) (5)
Intravenous Immunoglobulin Treatment of Experimental T Cell-mediated Autoimmune Disease Upregulation of T Cell Proliferation and Downregulation of Tumor Necrosis Factor a Secretion (2013) (5)
Structured treatment interruptions to control HIV-1 infection (2000) (5)
Regulation of T-lymphocyte autosensitization. (1973) (4)
Non-Type Specific Resistance to Group A Streptococci in Germ Free and Conventional Mice.∗ (1963) (4)
SLE-key (R) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP (R) (4)
Insulin-dependent diabetes mellitus. (1989) (4)
Antiinflammatory therapy for rheumatoid arthritis? (2008) (4)
Cellular Immunity in Vitro : Specific Antigen Induces Sensitization and Activates a Nonspecific Cytolytic Effect (1971) (4)
Unresolved questions in clinical T cell vaccination. (1991) (4)
Paradoxical Effects of Suppressor T Cells in Adjuvant Arthritis: Neural Network Analysis (1992) (4)
Experimental aspects of T cell vaccination. (1993) (4)
Membrane Dynamics and Calcium Signaling (2017) (4)
Self-Organization and Meaning in Immunology (2006) (4)
Molecular Aspects of the Processing and Presentation of Avidin by Macrophages to T Lymphocytes (1983) (4)
Longevity Genes (2015) (4)
Guanine polynucleotides are self‐antigens for human natural autoantibodies and are significantly reduced in the human genome (2015) (4)
Permanent Lines of T Lymphocytes Specific for Acetylcholine Receptors: A Clonal Approach to Study the Pathogenesis of Myasthenia Gravis (1984) (4)
Induction of experimental autoimmune encephalomyelitis by native myelin basic protein‐activated T lymphocyte lines (1992) (4)
T Cell Vaccination (1998) (3)
HYDROCORTISONE AND INHIBITORS OF PROSTAGLANDIN SYNTHESIS POTENTIATION OF ALLOGRAFT SURVIVAL IN MlCE (1981) (3)
Pillars Article: The Rapid Isolation of Clonable Antigen-specific T Lymphocyte Lines Capable of Mediating Autoimmune Encephalomyelitis. Eur J Immunol. 1981.11: 195-199. (2017) (3)
Protein 60 and Tetanus Toxoid: Self-Heat Shock Streptococcus pneumoniae Carriers in a Conjugate Vaccine for Proteins and Their Derived Peptides as (2003) (3)
Corrigendum to "Stress Proteins and Cytokines are Urinary Biomarkers for Diagnosis and Staging of Bladder Cancer" [Eur Urol 2011;59:113-9]. (2011) (3)
Immunoregulation: studies of physiological and therapeutic autoreactivity by T cell vaccination (2004) (3)
The meaning of the immunological homunculus. (1993) (3)
Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans (2021) (3)
Mice developing mammary tumors evolve T cell sequences shared with human breast cancer patients (2018) (3)
The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction (2020) (3)
On Using Divide and Conquer in Modeling Natural Systems (2009) (3)
Immunologically specific treatment of spontaneous insulin-dependent diabetes mellitus of NOD mice. (1992) (3)
DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F1 Mice from Systemic Lupus Erythematosus. (2020) (3)
Autoimmunity shifts paradigms. (1994) (3)
Modeling Biology using Generic Reactive Animation (2010) (3)
Molecular events in the processing of avidin by antigen-presenting cells (APC) (2004) (3)
DNA vaccine encoding heat shock protein 90 protects from murine lupus (2020) (3)
T lymphocyte clones and experimental autoimmune diseases. (1985) (3)
Mutations at H-2K or H-2D alter immune response phenotype of autoimmune thyroiditis (2004) (3)
CELLULAR INTERACTIONS CONTROLLING THE IMMUNE REACTIVITY OF T‐LYMPHOCYTES * (1975) (3)
Immunospecific depletion of graft-versus-host-reactive lymphocytes using sensitized syngeneic initiator T lymphocytes. (1979) (3)
On Causality and Evolution (2000) (2)
Antigen-microarray profiling of antibodies in SLE: A personal view of translation from basic science to the clinic (2018) (2)
Functional activation of encephalitogenic T cells in the absence of antigen-presenting cells. (1995) (2)
Biological Reactive Intermediates V (1996) (2)
P277 prevents NOD diabetes via down-regulation of interferon diabetes via down-regulation of interferon-γ (2009) (2)
Analysis of the autoimmune infiltrate in experimental encephalomyelitis. (1992) (2)
An α‐chain TCR CDR3 peptide can enhance EAE induced by myelin basic protein or proteolipid protein (1996) (2)
The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction. (2020) (2)
Infectious Diseases and Nanomedicine III (2018) (2)
Cell Vaccination Benefits Relapsing Progressive Multiple Sclerosis Patients : A Randomized , Double-Blind Clinical Trial (2012) (2)
Cell interactions in the recruitment of effector lymphocytes. (1975) (2)
A network approach to controlling pathogenic inflammation (2013) (2)
Introduction to Immune Networks (1989) (2)
Antigen-Microarray Profiling of Antibodies in SLE: A Personal View ofTranslation from Basic Science to the Clinic (2016) (2)
HSP60: A Pleiotropic Immune Signal (2007) (2)
T-cell recruitment: a tool for specific immunosuppression. (1982) (2)
Arresting beta-cell destruction in type 1 diabetes mellitus: mobilizing homuncultar autoimmunity to treat autoimmune disease. (2014) (2)
Recruitment of effector T lymphocytes by initiator T lymphocytes: application for specific immunosuppression. (1981) (2)
The interactions between antigen-presenting cells (APC) and T lymphocytes. (1984) (2)
Vaccination against experimental autoimmune disease using autoimmune T-lymphocytes. (1988) (2)
Differentiation of cytotoxic T lymphocytes enhanced by T cell factors produced during mixed lymphocyte interactions. (1976) (2)
Microscopic Discrete Proliferating Components Cause the Self-Organized Emergence of Macroscopic Adaptive Features in Biological Systems (2000) (2)
Structural analysis of insulin determinants seen by T cells directed by H-2 genes (2004) (2)
Recruitment of effector lymphocytes by initiator lymphocytes: recruited lymphocytes are immunospecific. (1976) (1)
Towards T cell vaccination in rheumatoid arthritis. (1994) (1)
Protection of mice against mycobacterial infection by lymphoid cell vaccination. (1994) (1)
Extracellular matrixinduces tumournecrosis factor-a secretion by an interaction betweenresting ratCD4 + T cells andmacrophages (1993) (1)
Avraham Ben-Nun-Pioneer, fighter, friend. (2019) (1)
Response to “Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together” (2007) (1)
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS MEDIATED BY T INFLUENCES IMMUNODOMINANT EPITOPE OF BASIC PROTEIN' LYMPHOCYTE LINES: GENOTYPE OF ANTIGEN-PRESENTING CELLS (1986) (1)
Biomarker vaccines (2009) (1)
Pemphigus vulgaris is characterized by low IgG reactivities to specific self‐antigens along with high IgG reactivity to desmoglein 3 (2014) (1)
Early demyelination can be detected in vitro by a myelin associated optical signal (1987) (1)
Variable mapping of H-2 genes controlling the T-cell response to antigenic determinants of insulin (1982) (1)
Thymocyte maturation in AKR leukemia. (1976) (1)
MOLECULAR EVENTS IN THE INDUCTION OF AUTOSENSITIZATION OF INITIATOR T LYMPHOCYTES1 (1975) (1)
The Aging Paradox and Autoimmune Disease by E. Talor and N.R. Rose (1991) (1)
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Interpersonal struggle or interpersonal bonding? Comment on "personality from a cognitive-biological perspective", by Y. Neuman. (2014) (1)
Molecular events in the processing of avidin by antigen-presenting cells (APC) (2004) (1)
Evaluation of Long-Term Treatment Effect in a Type 1 Diabetes Intervention Trial: Differences After Stimulation With Glucagon or a Mixed Meal. Diabetes Care 2014;37:1384–1391. DOI: 10.2337/dc13-1392 (2014) (1)
MS and T-cell futurism (1991) (1)
Autoimmunity to receptors. (1989) (1)
Use of a pressor agent in shock accompanying myocardial infarction. (1952) (1)
T Cell Ir phenotype modified by excising primary antigen deposit (2004) (1)
Immunity to bacterial infection (excluding mycobacteria) (PP-060) (2010) (1)
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IMMUNOSPECIFIC DEPLETION OF LYMPHOCYTES REJECTING SKIN ALLOGRAFTS USING SENSITIZED SYNGENEIC INITIATOR T LYMPHOCYTES (1980) (1)
Execution , and Visualization of Thymic T-Cell Maturation Toward Rigorous Comprehension of Biological Complexity : data (2003) (1)
Absence of major histocompatibility complex restriction in the interaction between processed basic protein and Ia of two rat strains. (1989) (1)
The Role of Micro-organisms in Non-infectious Diseases (1990) (1)
Production and properties of anti-idiotypic antibodies that recognize insulin receptor. (1989) (1)
Processed antigen and MHC molecules. (1985) (1)
Genes of the major histocompatibility complex control transmission of information between initiator and recruited T lymphocyte. (1982) (1)
Th 1 Polarization Secreted by Activated T Cells and Induces Vascular Endothelial Growth Factor Is Angiogenesis-Inflammation Cross-Talk : (2004) (1)
T Cell Vaccines for Autoimmune Diseases (1993) (1)
Inflammation Adjuvants in Sterile and Septic Heat Shock Proteins as Endogenous (2013) (0)
Reviews Thoughts on the Pathogenesis of Type 1 Diabetes and on the Arrest of Autoimmune Beta-Cell Destruction by Peptide p 277 Vaccination (2004) (0)
p277 PEPTIDE ANALOG, PHARMACEUTICAL COMPOSITION THEREOF FOR THE TREATMENT AND DIAGNOSIS OF DIABETES (1995) (0)
Autoimmune Arthritis Induced by Immunization to Mycobacterial Antigens (2020) (0)
Contents, Vol. 108, 1995 (1995) (0)
Transcription Factors and Hepatitis Model via Innate Regulation of Heat Shock Protein 60 Inhibits Th1-Mediated (2005) (0)
Compartmentalization of disease regulation: Acquiring and maintaining resistance to EAE is associated with anterior uveitis (1994) (0)
Regulation of NOD mouse autoimmune diabetes by T-cells that recognize a T-cell receptor idiotope (2009) (0)
The possible role of SOCS3 in regulation of transcription factors in T cells. (2005) (0)
Process for the preparation of therapeutically useful peptide (1996) (0)
Spontaneous and Induced Signaling, Protects B Cells from Apoptosis, Heat Shock Protein 60, via MyD88 Innate (0)
Destruction of CD4 T Lymphocytes Alone Cannot Account for their Long-term Decrease in AIDS (2000) (0)
The mycobacterial 65 kD and autoimmune arthritis heat-shock protein Rheum o ! (0)
Inflammation Cells : Effects on Signaling , Chemotaxis , and Suppressor of Cytokine Signaling 3 in T Cytokine-Associated Negative Regulator Heat Shock Protein 60 Activates (2005) (0)
peptide inhibitors to mediate stress responses (2005) (0)
Autoantibody profiling for Systemic Lupus Erythematosus diagnosis using the Immunarray CHIP™ (P4018) (2013) (0)
Dominance, Crypticity and Autoimmune Disease (1999) (0)
Analysis of H-2 gene regulation of the response of T lymphocytes to insulin using synthetic antigenic determinants and anti-idiotypes (1981) (0)
Interactions of Initiator and Recruited T Lymphocytes in Cell-Mediated Immunity (1976) (0)
Cytokines Th 1 / Th 2 Transcription Factors and Hepatitis Model via Innate Regulation of Heat Shock Protein 60 Inhibits Th 1-Mediated (2005) (0)
This information is current as by Lipopolysaccharide Is Conducive Signaling Induced by a Conjugate Vaccine or Macrophages and Dendritic Cells : TLR 4 ofImmunogenic When Present on the Surface Pneumococcal Capsular Polysaccharide Is Eisenbach (2008) (0)
GVH-reactive lymphocytes are recruited by sensitized syngeneic initiator T-lymphocytes. (1976) (0)
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Chapter 3 – On Cognition (2000) (0)
Immunotherapy of tumor metastases by in vitro sensitized lymphocytes. (1975) (0)
Intravenous immunoglobulins bind to encephalitogenic CD4+ T lymphocytes and suppress experimental autoimmune encephalomyelitis (1995) (0)
Fatty alcohols and fatty acid ester for treatment of inflammation (2002) (0)
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Diagnostisering and treatment of the insulinberoende sockersjuka. (1990) (0)
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Advances in Microbiology, Infectious Diseases and Public Health (2018) (0)
T-Cell Vaccination: An Insight Into T-Cell Regulation (2016) (0)
Stable Changes in Mesenchymal Stromal Cells from Multiple Myeloma Patients Revealed through Their Responses to Toll-Like Receptor Ligands and Epidermal Growth Factor (2011) (0)
T-Lymphocyte Vaccination Against Autoimmune Diseases (2020) (0)
Analysis of frequency and antigen specificity of T cells derived from the CNS lesion in EAE (1991) (0)
Proceedings: Migration of in vitro sensitized initiator T lymphocytes in recruitment. (1975) (0)
Heparin derived disaccharides down regulate proinflammatory cytokine secretion from intestinal epithelial cells (1999) (0)
Thymic reconstitution of H-2-linked T-cell responses to thyroglobulin or insulin (2004) (0)
The peptides and pharmaceutical compositions containing them (1997) (0)
REGULATION OF AUTOIMMUNITY BY THE MODE OF PRESENTATION OF AUTOANTIGEN TO LYMPHOCYTES (1977) (0)
Differential Immune Recognition of Heat-Shock Protein 60 Epitopes in Type 1 Diabetes (2007) (0)
Towards T Cell Vaccination in Rheumatoid Arthritis (Part 1 of 2) (1994) (0)
Composition for the prevention of metastasis (1987) (0)
A polypeptide useful for the alleviation, treatment and diagnosis of autoimmune diseases, particularly arthritis (1987) (0)
Vaccination studies in type 1 diabetes (2002) (0)
Anti-Ergotypic Regulation of the Immune Response (2007) (0)
Heart Failure: From Research to Clinical Practice (2018) (0)
4.5. Vaccination Therapy Against Autoimmune Diseases (1996) (0)
Recruitment of Effector Lymphocytes by Initiator Lymphocytes (1976) (0)
Proceedings: The helper effect of mixed lymphocyte culture supernatants on an in vitro T cell-mediated mouse transplantation reaction. (1975) (0)
Cytotoxic t-lymphocytes induced in vitro by antigen-fed macrophages. Abstr. (1976) (0)
36 – p53 AUTOANTIBODIES (2007) (0)
A Similar Motif Shared by HIV-1 gp41 and TCRA Trans-Membrane Domains Exploited by the HIV Virus to Modulate T-Cell Proliferation (2011) (0)
Abstract 1024: Auto-Antibody Serum Profile as Novel Biomarker for Acute Myocardial Infarction (2009) (0)
Immune Computation and COVID-19 Mortality: A Rationale for IVIg. (2020) (0)
Towards T Cell Vaccination in Rheumatoid Arthritis (Part 2 of 2) (1994) (0)
Heat Shock Protein 60 and the Regulation of Autoimmunity (2020) (0)
ﬁghter, friend (2019) (0)
Dossier:Autoimmunity and Biotherapy The natural autoantibody repertoire and autoimmune disease (2004) (0)
Erratum: Hauben et al., “Passive or Active Immunization with Myelin Basic Protein Promotes Recovery from Spinal Cord Injury Contusion” (2016) (0)
Erratum (2009) (0)
Cohen Modeling , Execution , and Visualization of Thymic T-Cell Maturation Toward Rigorous Comprehension of Biological Complexity : Material Supplemental (2003) (0)
Intravenous immunoglobulin treatment in multiple sclerosis. (1995) (0)
The effector functions of regulatory T cells in immune regulation Regulatory T cells and immune computation (2008) (0)
Compositions for the prevention of plastic rejection. (1987) (0)
[Self-tolerance and autoimmunity. A new concept and its significance]. (1974) (0)
Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma (2018) (0)
Subtilisin Enzymes (1996) (0)
39 - Type I Diabetes Mellitus, Infection and Toll-Like Receptors (2004) (0)
The IDDM autoimmune process, markers and beta-cell regeneration: panel discussion (1993) (0)
Heterogeneity in the generation of cytotoxic t lymphocytes in vitro revealed by sensitivity to hydrocortisone. Abstr. (1976) (0)
What's next in specific immune therapy? (1998) (0)
T lymphocytes present in spinal cords of rats suffering from autoimmune encephalomyelitis are activated to interact with extracellular matrix and secrete TNFα (1991) (0)
Idiotypic network and diseases: Edited by Jan Cerny and Jacques Hiernaux. American Society for Microbiology, Washington DC, 1990. 243 pp (1991) (0)
BIOMARKERS, SELF-ANTIGENS & THE IMMUNOLOGICAL HOMUNCULUS (2012) (0)
THE IMlVIUNE ACTIVATION AND SPECIFIC INHIBITION OF SELF-RECOGNIZING THYMus-DERIVED LYMPtIOCYTES* BY IRUN R. COHEN ANn (2003) (0)
A method for non-insulin dependent diabetes mellitus (IDDM) and in vitro diagnosis of the polypeptide useful in the kit and (1990) (0)
Vaccination studies in type 1 diabetes. Authors' reply (2002) (0)
Peptides, used as a carrier in immunogenic constructs which are useful in the development of synthetic vaccines (1995) (0)
7 Weak Links and the Stability of Organisms (2006) (0)
Preparation of T-cells and T-cell membranes, suitable for the prevention and treatment of autoimmune diseases. (1989) (0)
Chapter 4 – On Immunity (2000) (0)
Unmodified Live Tumor Cells Gliomas by Subcutaneous Exposure to Split Immunity : Immune Inhibition of Rat (2011) (0)
Cell membrane drug-containing proteins for the treatment of autoimmune diseases and methods for their preparation (1984) (0)
Diabetes: from Research to Clinical Practice: Volume 4 (2021) (0)
Immune response phenotype of insulin-presenting cells modified by insertion of H-2 gene products into cell membranes (1981) (0)
AUTOSENSITIZATIO N IN VITRO (2004) (0)
Use of Copolymer 1 and related peptides and polypeptides and T cell treated with the same, for neuroprotective therapy. (2001) (0)
Activation of the AktCREB signaling axis by a prolinerich heptapeptide confers resistance to stressinduced celldeath and inflammation (2017) (0)
Polypeptides and their derivatives and their use in pharmaceutical and diagnostic compositions. (1988) (0)
Mice / MyD88Encephalomyelitis in Adoptive Transfer Experimental IL-10 Mediates Resistance to (2010) (0)
Subject Index Vol. 108, 1995 (1995) (0)
Antigen-chip technology for accessing global information concerning the state of the body (2005) (0)
Polypeptides and derivatives thereof and to their use in pharmaceutical and diagnostic compositions (1988) (0)
Chapter 5 – On Autoimmunity (2000) (0)
INFECTIONS, BIOMARKERS, AND VACCINES (2014) (0)
FACILITATION OF THE SENSITIZATION PHASE AND INHIBITION OF THE EF)~ECTOR PHASE OF A LYMPHOCYTE ANTI-FIBROBLAST REACTION* (2004) (0)
Anti-inflammatory mechanisms of NAP in neuroprotection (2006) (0)
OF INFORMATION BETWEEN INITIATOR AND RECRUITED T LYMPHOCYTEI (1982) (0)
"Aleppo" and "Sunset" (2017) (0)
Manipulation of Autoimmune Diseases Using Autoimmune T Lymphocytes (1985) (0)
functions Toll-like receptors and their ligands control mesenchymal stem cell (2012) (0)
P277 peptide analogs and pharmaceutical compositions containing them for the treatment of diabetes and diagnosis (1997) (0)
Author response: T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences (2017) (0)
Autoimmune Inflammation and Multiple Sclerosis (2004) (0)
Polypeptide, its derivative, drug and diagnostic composition containing it (1988) (0)
MS and T-cell futurism (1992) (0)
Preparations and methods of treating T cell mediated diseases (1996) (0)
Polypeptides and derivatives thereof, as well as the use thereof in pharmaceutical and diagnostic compositions. (1987) (0)
AB1163 Antibodies binding synthetic oligonucleotides distinguish lupus from rheumatoid arthritis, scleroderma and sjogren's syndrome (2017) (0)
MRI of the self molecules bound by maternal and cord autoantibodies Antibody Cord IgM (2007) (0)
The interaction between initiator and recruited T lymphocytes (1979) (0)
BN Cardiac Allograft Survival in Wistar Recipients Treated with T Cell Vaccination (0)
Immunity to p 53 Induced by an Idiotypic Network of Anti-p 53 Antibodies : Generation of Sequence-specific Anti-DNA Antibodies and Protection from Tumor Metastasis 1 (2006) (0)
fatty alcohols: Anti-inflammatory and fatty acid ester as an antigen carrier (2002) (0)
The paradigms of causality and treatment for autoimmune disease. (2000) (0)
Eli Sercarz 1934–2009 (2010) (0)

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