Isabelle M. Germano
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Neurosurgeon, Mt. Sinai staff and faculty
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Why Is Isabelle M. Germano Influential?
(Suggest an Edit or Addition)According to Wikipedia, Isabelle M. Germano is a neurosurgeon and professor of neurosurgery, neurology, and oncology at the Icahn School of Medicine at Mount Sinai Hospital. She is a Fellow of the American College of Surgeons and the American Association of Neurological Surgeons. Germano works with image-guided brain and spine surgery.
Isabelle M. Germano's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells (2004) (956)
- Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. (2003) (574)
- Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat. (1995) (438)
- Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3 (2005) (383)
- Kynurenate inhibition of cell excitation decreases stroke size and deficits (1987) (192)
- Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy. (2003) (175)
- The future of neurosurgery: a white paper on the recruitment and retention of women in neurosurgery. (2008) (174)
- The therapeutic value of nimodipine in experimental focal cerebral ischemia. Neurological outcome and histopathological findings. (1987) (149)
- Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide. (2003) (146)
- Adenovirus/Herpes Simplex-Thymidine Kinase/Ganciclovir Complex: Preliminary Results of a Phase I trial in Patients with Recurrent Malignant Gliomas (2003) (141)
- Neuronal Migration Disorders Increase Susceptibility to Hyperthermia‐Induced Seizures in Developing Rats (1996) (141)
- Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter. (2001) (138)
- Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes. (2012) (131)
- Intracranial meningiomas of the first two decades of life. (1994) (128)
- Frameless stereotaxy for surgery of the epilepsies: preliminary experience. Technical note. (1994) (126)
- Neuropsychological functioning following bilateral subthalamic nucleus stimulation in Parkinson's disease. (2004) (120)
- Reoperation for recurrent temporal lobe epilepsy. (1994) (115)
- ACR Appropriateness Criteria Headache. (2014) (114)
- Intracerebral hemorrhage occurring remote from the craniotomy site. (1996) (113)
- Intrathecal baclofen for dystonia: Benefits and complications during six years of experience (2000) (99)
- Positive trends in neurosurgery enrollment and attrition: analysis of the 2000-2009 female neurosurgery resident cohort. (2016) (98)
- Histopathological follow-up study of 66 cerebral arteriovenous malformations after therapeutic embolization with polyvinyl alcohol. (1992) (98)
- Targeting glioma stem cells: A novel framework for brain tumors (2011) (96)
- Unilateral stimulation of the subthalamic nucleus in Parkinson disease: a double-blind 12-month evaluation study. (2004) (96)
- Clinical use of the optical digitizer for intracranial neuronavigation. (1999) (93)
- Tracking Career Paths of Women in Neurosurgery (2018) (74)
- ACR appropriateness criteria on metastatic bone disease. (2010) (73)
- Rapid differential diagnosis of cerebral toxoplasmosis and primary central nervous system lymphoma by thallium-201 SPECT. (1996) (71)
- Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review. (2016) (66)
- Primary brain tumors, neural stem cell, and brain tumor cancer cells: Where is the link? (2010) (66)
- Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide (2003) (63)
- Evidence of Enhanced Kindliig and Hippocampal Neuronal Injury in Immature Rats with Neuronal Migration Disorders (1998) (63)
- Age-dependent vulnerability to seizures. (1999) (62)
- Attrition rates in neurosurgery residency: analysis of 1361 consecutive residents matched from 1990 to 1999. (2015) (62)
- Antitumour effect of cyclin-dependent kinase inhibitors (p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1) on malignant glioma cells (2003) (62)
- Stem cells as therapeutic vehicles for the treatment of high-grade gliomas. (2012) (59)
- Advanced Techniques in Image-Guided Brain and Spine Surgery (2002) (59)
- Caspase-8 gene therapy using the human telomerase reverse transcriptase promoter for malignant glioma cells. (2002) (58)
- Transplacentally induced neuronal migration disorders: An animal model for the study of the epilepsies (1998) (58)
- Increased seizure susceptibility in adult rats with neuronal migration disorders (1997) (57)
- Clinical evaluation of multimodality registration in frameless stereotaxy. (1999) (52)
- Correlation of histopathological features and proliferative potential of gliomas. (1989) (52)
- ACR Appropriateness Criteria Follow-Up of Malignant or Aggressive Musculoskeletal Tumors. (2016) (51)
- Clinical experience with intracranial brain needle biopsy using frameless surgical navigation. (1998) (48)
- Congress of Neurological Surgeons Systematic Review and Evidence‐Based Guidelines on the Role of Radiosurgery and Radiation Therapy in the Management of Patients With Vestibular Schwannomas (2018) (46)
- Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro (2012) (45)
- Multiparametric MRI for Differentiation of Radiation Necrosis From Recurrent Tumor in Patients With Treated Glioblastoma. (2018) (44)
- A program for neuropsychological investigation of deep brain stimulation (PNIDBS) in movement disorder patients: development, feasibility, and preliminary data. (2000) (43)
- The NeuroStation System for image-guided frameless stereotaxy (1995) (42)
- The role of thallium-201 uptake and retention in intracranial tumors after radiotherapy. (1997) (42)
- Gene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside (2009) (40)
- A novel treatment of human malignant gliomas in vitro and in vivo: FADD gene transfer under the control of the human telomerase reverse transcriptase gene promoter. (2001) (38)
- Apoptosis in human glioblastoma cells produced using embryonic stem cell-derived astrocytes expressing tumor necrosis factor-related apoptosis-inducing ligand. (2006) (38)
- Clinical outcome of vertebral compression fracture after single fraction spine radiosurgery for spinal metastases (2016) (34)
- Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis, radiosensitization, and overcomes temozolomide resistance in malignant gliomas (2010) (32)
- ACR Appropriateness Criteria® Follow-up and Retreatment of Brain Metastases (2012) (32)
- Trends in United States neurosurgery residency education and training over the last decade (2009-2019). (2020) (32)
- Enhanced proapoptotic effects of tumor necrosis factor-related apoptosis-inducing ligand on temozolomide-resistant glioma cells. (2007) (32)
- ACR Appropriateness Criteria® pre-irradiation evaluation and management of brain metastases. (2014) (31)
- "Footprint-free" human induced pluripotent stem cell-derived astrocytes for in vivo cell-based therapy. (2014) (30)
- Magnetic resonance imaging and 31P magnetic resonance spectroscopy for evaluating focal cerebral ischemia. (1989) (30)
- ACR Appropriateness Criteria: single brain metastasis. (2010) (29)
- In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas. (2009) (29)
- ACR Appropriateness Criteria® Hearing Loss and/or Vertigo. (2018) (27)
- Machine Learning in Neuro-Oncology: Can Data Analysis from 5,346 Patients Change Decision Making Paradigms? (2019) (27)
- Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells (2014) (26)
- American College of Radiology appropriateness criteria on multiple brain metastases. (2009) (26)
- Embryonic stem cell-derived astrocytes expressing drug-inducible transgenes: differentiation and transplantion into the mouse brain. (2005) (25)
- The impact of African-trained neurosurgeons on sub-Saharan Africa. (2020) (24)
- ACR Appropriateness Criteria® Neuroendocrine Imaging. (2019) (24)
- Human iPSC for Therapeutic Approaches to the Nervous System: Present and Future Applications (2015) (23)
- Review of global neurosurgery education: Horizon of Neurosurgery in the Developing Countries (2020) (22)
- Interval Change in Diffusion and Perfusion MRI Parameters for the Assessment of Pseudoprogression in Cerebral Metastases Treated With Stereotactic Radiation. (2018) (21)
- on malignant glioma cells (2003) (21)
- Correlation of factors predicting intraoperative brain shift with successful resection of malignant brain tumors using image-guided techniques. (2005) (21)
- No circulating cytomegalovirus in five patients with glioblastoma multiforme. (2011) (20)
- High Energy Phosphate Metabolism in Experimental Permanent Focal Cerebral Ischemia: An in vivo 31P Magnetic Resonance Spectroscopy Study (1988) (20)
- Evaluation of factors predicting accurate resection of high-grade gliomas by using frameless image-guided stereotactic guidance. (2003) (20)
- Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas? (2011) (20)
- INFLAMMATORY PSEUDOTUMOR ASSOCIATED WITH HIV, JCV, AND IMMUNE RECONSTITUTION SYNDROME (2009) (19)
- Neurosurgical treatment of movement disorders (1998) (19)
- Radiosurgery for high-grade glioma (2012) (17)
- Embryonic stem cell-derived astrocytes: a novel gene therapy vector for brain tumors. (2005) (17)
- A prospective emergency department-based study of pattern and outcome of neurologic and neurosurgical diseases in Haiti. (2014) (17)
- Stem cells and gliomas: past, present, and future (2014) (16)
- LINAC and gamma knife radiosurgery (2000) (15)
- Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats. (1997) (14)
- The First Neurosurgery Boot Camp in Southeast Asia: Evaluating Impact on Knowledge and Regional Collaboration in Yangon, Myanmar. (2018) (13)
- Analysis of Local Control and Pain Control After Spine Stereotactic Radiosurgery Reveals Inferior Outcomes for Hepatocellular Carcinoma Compared With Other Radioresistant Histologies. (2019) (13)
- Magnetic resonance imaging in the evaluation of nimodipine-treated acute experimental focal cerebral ischemia. (1986) (13)
- Gene delivery by embryonic stem cells for malignant glioma therapy: hype or hope? (2008) (13)
- Combined magnetic resonance imaging and spectroscopy in experimental regional injury of the brain. Ischemia and impact trauma. (1986) (13)
- Planning and Executing the Neurosurgery Boot Camp: The Bolivia Experience. (2017) (12)
- Workforce Analysis of Spine Surgeons Involved with Neurological and Orthopedic Surgery Residency Training. (2019) (11)
- Pregnancy and parental leave among neurosurgeons and neurosurgical trainees. (2020) (11)
- Down-regulation of telomerase activity in malignant glioma cells by p27KIP1. (2003) (10)
- ACR Appropriateness Criteria® Tinnitus. (2017) (10)
- Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update (2020) (9)
- Transsulcal approach to mesiotemporal lesions. Anatomy, technique, and report of three cases. (1996) (9)
- 21: Thoracic Instrumentation: Stereotactic Navigation for Placement of Pedicle Screws in the Thoracic Spine (2002) (8)
- 5-Aminolevulinic acid for enhanced surgical visualization of high-grade gliomas: a prospective, multicenter study. (2021) (8)
- Making a match: trends in the application, interview, and ranking process for the neurological surgery residency programs. (2021) (7)
- Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology? (2009) (6)
- PRE-IRRADIATION EVALUATION AND MANAGEMENT OF BRAIN METASTASES (2014) (6)
- Communicating hydrocephalus after radiosurgery for vestibular schwannomas: does technique matter? A systematic review and meta-analysis (2019) (6)
- A Reusable Low-cost 3D Training Model for Aneurysm Clipping. (2020) (6)
- Resilience in the Face of the COVID-19 Pandemic: How to Bend and not Break (2020) (6)
- Web based pathology assessment in RTOG 98-04 (2014) (5)
- Anticonvulsant and Neuronal Protective Effects of Propofol on Experimental Status Epilepticus (1998) (5)
- Women Neurosurgeons in academic and other leadership positions in the United States. (2020) (5)
- Surgery for posterior fossa ependymomas in adults. (2018) (4)
- 2: Sources of Error in Image Registration for Cranial Image-Guided Neurosurgery (2002) (4)
- Deep Brain Stimulation for the Treatment of Parkinsonʼs Disease (2001) (4)
- FOLLOW-UP AND RETREATMENT OF BRAIN METASTASES (2014) (3)
- Scalp nerve blockade reduces pain after headframe placement in radiosurgery: a double blind, randomized clinical trial. (2013) (3)
- Racial and Ethnical Diversity Within the Neurosurgery Resident and Faculty Workforce in the United States (2022) (3)
- Correction to: Review of global neurosurgery education: Horizon of Neurosurgery in the Developing Countries (2020) (3)
- Paradoxical evolution of a cerebellar tuberculosis abscess after surgical drainage and antibiotic therapy (2014) (3)
- Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults (2021) (3)
- Surgical Techniques for Stereotactic Implant of Deep Brain Stimulators (2001) (2)
- 132 15 Image-Guided Brain Tumor Resection (2002) (2)
- Advances in the Neurosurgical Management of Adult Epilepsy (1997) (2)
- Direct endarterectomy of the middle cerebral artery for treatment of symptomatic stenosis: case report. (1993) (2)
- Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of targeted therapies and immunotherapies in the management of progressive glioblastoma (2021) (2)
- Academic Productivity of United States Neurosurgeons Trained Abroad. (2021) (1)
- SINGLE BRAIN METASTASIS (2012) (1)
- P17.07FENOFIBRATE AS A NOVEL THERAPEUTIC ADJUVANT FOR TARGETING GLIOMA STEM CELLS. (2014) (1)
- Long-term outcomes of acromegaly treated with fractionated stereotactic radiation: case series and literature review. (2017) (1)
- The Cognitive Effects of Radiotherapy for Brain Metastases (2022) (1)
- Breaking boundaries through Doctors Reaching Minority Men Exploring Neuroscience: a mentorship model to foster a pipeline for underrepresented minorities. (2022) (1)
- Acknowledgement of Reviewers 2012 (2013) (1)
- Do neurosurgeons follow the guidelines? A world-based survey on severe traumatic brain injury. (2021) (1)
- Tumor Volume Increase after Stereotactic Radiosurgery for Vestibular Schwannoma: Expected Radiographic Finding or Exception? (2010) (1)
- 3D simulation of aneurysm clipping: Data analysis (2021) (0)
- 14: Cerebrovascular Applications of Image-Guided Surgery (2002) (0)
- Biologic Subtypes as a Predictor of Local Control of Breast Cancer Brain Metastases after Stereotactic Radiosurgery (2018) (0)
- P17.33STEM CELLS AND GLIOMAS: PAST, PRESENT, AND FUTURE (2014) (0)
- P17.07. FENOFIBRATE AS A NOVEL THERAPEUTIC ADJUVANT FOR TARGETING GLIOMA STEM CELLS (2014) (0)
- IDH-mutant astrocytoma with EGFR amplification—Genomic profiling in four cases and review of literature (2022) (0)
- Introduction to special issue dedicated to the 35th anniversary of the joint section on tumors (2021) (0)
- 22: Image Guidance for Scoliosis (2002) (0)
- SU-E-T-584: Dosimetric Comparison Between Static IMRT and VMAT for a Four- Lesion Brain Treatment. (2012) (0)
- 24: Computer-Assisted Image-Guided Fluoroscopy (Virtual Fluoroscopy) (2002) (0)
- 9: Videotactic Surgery A Volume as an Image-Guided Target (2002) (0)
- MULTIPLE BRAIN METASTASES (2014) (0)
- Current Neurosurgical Care in Ethiopia Using the Lens of the Lancet Global Health Commission on High-Quality Health Systems. (2023) (0)
- Congress of Neurological Surgeons Systematic Review and Evidence-based Guidelines Update on the Role of Targeted Therapies and Immunotherapies in the Management of Progressive Glioblastomaoncolo (2021) (0)
- 4: The Optical Digitizer (2002) (0)
- 8: Image-Guided Neurosurgery Combining Mechanical Arm and Optical Digitizer (2002) (0)
- 5: The Mechanical Arm System (2002) (0)
- CTIM-09. PHASE I STUDY OF PD-L1 INHIBITION WITH AVELUMAB AND LASER INTERSTITIAL THERMAL THERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA (2021) (0)
- In the pursuit of glioma diagnosis - the challenges and opportunities of deep neural network augmented analyses. (2020) (0)
- 16: Intraoperative Image Update by Interface with Ultrasound (2002) (0)
- 10: Endoscopic Image-Guided Surgery (2002) (0)
- 7: The Passive Navigational System Application and Procedure for Use in the Operating Room (2002) (0)
- Introduction: High-Grade Gliomas (2003) (0)
- Evidence of Enhanced Kindli Injury in Immature Rats with ig and Hippocampal Neuronal Neuronal Migration Disorders (1998) (0)
- Gene Promoter Catalytic Subunit ( Human Telomerase Reverse Transcriptase ) Constitutively Active Caspase-6 Using the Human Telomerase Treatment of Malignant Glioma Cells with the Transfer of Updated (2001) (0)
- HISTOPATHOLOGICAL FINDINGS OF CEREBRAL ARTERIOVENOUS MALFORMATIONS (AVMʼS) TREATED BY EMBOLIZATION WITH POLYVINYL ALCOHOL (PVA): 117 (1990) (0)
- Emerging Neurosurgery in Africa Abdeslam El Khamlichi M.D. AGRI-BYS SARL Publisher 2019 275 pages $25ISBN: 978-9920-639-00-2 (2020) (0)
- 727 Molecular Response of Glioblastoma Multiforme to Radiation (2001) (0)
- 23: Image-Guided Lumbar Instrumentation (2002) (0)
- Gadopentetate-Induced status epilepticus (1995) (0)
- Long-Term Outcomes and Toxicities of Growth Hormone (Somatotroph)–Secreting Pituitary Macroadenomas Treated With Adjuvant Fractionated Stereotactic Radiation Therapy (FSRT) (2014) (0)
- A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma (2023) (0)
- Appropriateness Criteria ® on Metastatic Bone Disease Permalink (0)
- Do Effects of Febrile Seizures Differ in Normal and Abnormal Brain (2002) (0)
- Book Review (2020) (0)
- RADI-29. BIOLOGIC SUBTYPES OF BREAST CANCER BRAIN METS AS A PREDICTOR OF LOCAL CONTROL AFTER STEREOTACTIC RADIOSURGERY (2019) (0)
- The changing landscape of ependymomas: diagnostic and treatment approaches. (2018) (0)
- 18: Image-Guided Epilepsy Surgery (2002) (0)
- 17: Intraoperative Image Update by Magnetic Resonance Imaging (2002) (0)
- Subspecialty and Training Preferences for United States Neurosurgery Faculty with International Training. (2022) (0)
- 11: Robotic Microscopes (2002) (0)
- Abstract T P198: Cerebrovascular Disease Patterns among Emergency Room Admissions in 4070 Consecutive Patients of Haiti (2014) (0)
- Walking out on the boys [2] (multiple letters) (2000) (0)
- Letter: A Neurosurgical Community Under Attack. (2021) (0)
- 213 5-Aminolevulinic Acid for Enhanced Surgical Visualization of High-Grade Gliomas: A Prospective, Multicenter Study (2022) (0)
- 19: New Directions in Atlas-Assisted tereotactic Functional Neurosurgery (2002) (0)
- Biologic subtypes as a predictor of local control in patients with brain metastases from breast cancer after stereotactic radiosurgery (2020) (0)
- Multidisciplinary management of metastatic spine disease: initial symptom-directed management. (2020) (0)
- 6: The Magnetic System (2002) (0)
- Diversity within the Neurosurgical Oncology Workforce in the United States: A Cross-Sectional Study with Proposed Strategies to Pave the Path Forward. (2022) (0)
- 12: Image-Guided Robotic Radiosurgery (2002) (0)
- Developmental Aspects of Childhood Seizures1 (1995) (0)
- Introduction. Neurosurgical international education. (2020) (0)
- 25: Controversies in Image-Guided Spine Surgery (2002) (0)
- THALLIUM-201 BRAIN SPECT AND CT/MRI IMAGING FOR DIFFERENTIAL DIAGNOSIS OF CEREBRAL TOXOPLASMOSIS AND PRIMARY CNS LYMPHOMA (1996) (0)
- 15: Image-Guided Brain Tumor Resection (2002) (0)
- Accuracy of Exactrac Image Fusion Depends on Lesion Location and Fusion Parameter Settings (2009) (0)
- PATH-01. BRAIN METASTASES FROM ENDOMETRIAL CARCINOMA: TUMOR GENETIC ALTERATIONS IN A CASE SERIES AND META-ANALYSIS (2020) (0)
- 20: Image-Guided Cervical Instrumentation (2002) (0)
- Third Ventricular Subependymomas: Clinical features and Outcomes over Two Decades. (2023) (0)
- Traumatic Brain Injury Mortality and Correlates in Low- and Middle-Income Countries: A Meta-Epidemiological Study. (2023) (0)
- 3: Spinal Registration Accuracy and Error (2002) (0)
- Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Management of Progressive Glioblastoma in Adults: Update of the 2014 Guidelines (2022) (0)
- Clinical outcome of vertebral compression fracture after single fraction spine radiosurgery for spinal metastases (2015) (0)
- The Neurosurgery Enterprise and Its Stakeholders (2022) (0)
- High Frequency Stimulation of the Subthalamic Nucleus as a Treatment for Parkinson's Disease: A 12 Month Follow-up Study (1999) (0)
- 13: Image-Guided Brain Biopsy (2002) (0)
- 51. BRAIN METASTASES FROM ENDOMETRIAL CARCINOMA: TUMOR GENETIC ALTERATIONS IN A CASE SERIES AND META-ANALYSIS (2020) (0)
- 729 Gene Therapy for Recurrent Glioblastoma: Interim Report (2000) (0)
- 2019 Thallium-201 spect imaging after radiotherapy for brain tumors (BT): A step closer toward a clinical “histopathologic” interpretation (1996) (0)
- 422 Safety and Efficacy of Responsive Neurostimulation for the Treatment of Medically Refractory Epilepsy: A 5-Year Follow-Up Study (2022) (0)
- Preliminary Results of Thallium-201 SPECT Scanning in the Postradiosurgery Management of Malignant Brain Tumors: A Step Closer toward a Clinical ‘Histopathologic’ Interpretation (1996) (0)
- 1: Historical Perspective of the Components of Image-Guided Neurosurgery (2002) (0)
- SU‐E‐T‐893: A Standardized 11‐Field Treatment Plan for Radiosurgery to Spinal Lesions (2011) (0)
- Clin ical Paiw Clinical Evaluation of Multimodality Registration in Frameless Stereo (1999) (0)
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What Schools Are Affiliated With Isabelle M. Germano?
Isabelle M. Germano is affiliated with the following schools:
