Isabelle Vernos
Biochemist specialized in microtubules
Isabelle Vernos's AcademicInfluence.com Rankings
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Biology
Isabelle Vernos's Degrees
- Bachelors Biochemistry University of Oxford
Why Is Isabelle Vernos Influential?
(Suggest an Edit or Addition)According to Wikipedia, Isabelle Vernos is an ICREA research professor at the Center for Genomic Regulation in Barcelona. She received a PhD in biochemistry from the Autonomous University of Madrid followed by postdoctoral studies at Cambridge University. Between 1992 and 2005 she developed her research career at the European Molecular Biology Laboratory at the University of Heidelberg in Germany. Since 2005 she is an ICREA Research Professor at the Center for Genomic Regulation in Barcelona where she leads the group on Microtubule Function and Cell Division, the same year she also became a member of the European Molecular Biology Laboratory. In 2012 she was chosen to be part of the Spanish Secretary of State Advisory Council on Science, Technology and Innovation, an institution formed by scientists and social agencies to advise on development policies and scientific innovation and where she is the only woman. Since 2014 she has been a member of the scientific council of the European Research Council, the institution responsible for promoting high-level research in Europe.
Isabelle Vernos's Published Works
Published Works
- Ran Induces Spindle Assembly by Reversing the Inhibitory Effect of Importin α on TPX2 Activity (2001) (552)
- Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. (2003) (545)
- The Mitotic Spindle: A Self-Made Machine (2001) (478)
- Genetic organization of Drosophila bithorax complex (1985) (470)
- Gene Regulatory Networks in the Evolution and Development of the Heart (2006) (470)
- A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity (1998) (415)
- Tpx2, a Novel Xenopus Map Involved in Spindle Pole Organization (2000) (391)
- Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. (2001) (326)
- Dynactin is required for bidirectional organelle transport (2003) (319)
- Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells (2002) (317)
- Xklp15 a chromosomal xenopus kinesin-like protein essential for spindle organization and chromosome positioning (1995) (247)
- Xkid, a Chromokinesin Required for Chromosome Alignment on the Metaphase Plate (2000) (244)
- Localization of the Kinesin-like Protein Xklp2 to Spindle Poles Requires a Leucine Zipper, a Microtubule-associated Protein, and Dynein (1998) (213)
- Heterotrimeric Kinesin II Is the Microtubule Motor Protein Responsible for Pigment Dispersion in Xenopus Melanophores (1998) (187)
- Xklp2, a Novel Xenopus Centrosomal Kinesin-like Protein Required for Centrosome Separation during Mitosis (1996) (163)
- The Role of Hklp2 in the Stabilization and Maintenance of Spindle Bipolarity (2009) (155)
- The TACC proteins: TACC-ling microtubule dynamics and centrosome function. (2008) (153)
- A Kinesin-like Motor Inhibits Microtubule Dynamic Instability (2004) (152)
- Kinesin‐2 is a Motor for Late Endosomes and Lysosomes (2005) (146)
- Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis (2005) (142)
- Development and Biological Evaluation of Potent and Specific Inhibitors of Mitotic Kinesin Eg5 (2005) (131)
- Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'. (2004) (125)
- Microtubule assembly during mitosis – from distinct origins to distinct functions? (2012) (113)
- Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. (2004) (108)
- The Plant TPX2 Protein Regulates Prospindle Assembly before Nuclear Envelope Breakdown[W] (2008) (107)
- The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond (2016) (98)
- Role of Xklp3, a Subunit of the Xenopus Kinesin II Heterotrimeric Complex, in Membrane Transport between the Endoplasmic Reticulum and the Golgi Apparatus (1998) (96)
- Spindle-localized CPE-mediated translation controls meiotic chromosome segregation (2008) (92)
- K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly (2011) (92)
- Kinesin II Mediates Vg1 mRNA Transport in Xenopus Oocytes (2004) (91)
- Dissecting the role of Aurora A during spindle assembly (2008) (88)
- Chromosomes take the lead in spindle assembly. (1995) (83)
- Motors involved in spindle assembly and chromosome segregation. (1996) (82)
- Microtubule Nucleation in Mitosis by a RanGTP-Dependent Protein Complex (2015) (80)
- Acentrosomal Microtubule Assembly in Mitosis: The Where, When, and How. (2016) (76)
- Nek9 Phosphorylation of NEDD1/GCP-WD Contributes to Plk1 Control of γ-Tubulin Recruitment to the Mitotic Centrosome (2012) (73)
- A Role for Kinesin-2 in COPI-Dependent Recycling between the ER and the Golgi Complex (2006) (72)
- The mechanism of spindle assembly (2004) (69)
- Uncovering new substrates for Aurora A kinase (2010) (66)
- Aurora A kinase and its substrate TACC3 are required for central spindle assembly (2013) (64)
- Determinants for Aurora-A Activation and Aurora-B Discrimination by TPX2 (2004) (60)
- The Role of NEDD1 Phosphorylation by Aurora A in Chromosomal Microtubule Nucleation and Spindle Function (2013) (58)
- An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis (2015) (51)
- Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown (2018) (45)
- Multiple kinesin-like transcripts in Xenopus oocytes. (1993) (44)
- Microgravity effects on the oogenesis and development of embryos of Drosophila melanogaster laid in the Spaceshuttle during the Biorack experiment (ESA). (1989) (42)
- Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly (2015) (41)
- Analysis of heterodimer formation by Xklp3A/B, a newly cloned kinesin‐II from Xenopus laevis (2001) (40)
- Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication (2006) (37)
- Research management: Quotas are questionable (2013) (34)
- Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes (2002) (31)
- Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain (2016) (31)
- Kinesin subfamily UNC104 contains a FHA domain: boundaries and physicochemical characterization (2000) (30)
- Chromosome motors on the move (2001) (29)
- Protein 4.1R regulates interphase microtubule organization at the centrosome (2004) (28)
- Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division (2016) (28)
- Chromokinesin Xklp1 contributes to the regulation of microtubule density and organization during spindle assembly. (2005) (28)
- Chromokinesins: localization-dependent functions and regulation during cell division. (2011) (28)
- Chromosome motors on the move. From motion to spindle checkpoint activity. (2001) (27)
- Plant TPX2 and related proteins (2009) (26)
- Different forms of Ultrabithorax proteins generated by alternative splicing are functionally equivalent. (1990) (26)
- The role of microtubule dependent motors in centrosome movements and spindle pole organization during mitosis (1996) (26)
- The Kinesin Superfamily Motor Protein KIF4 Is Associated With Immune Cell Activation in Idiopathic Inflammatory Myopathies (2008) (24)
- Structure and Non-Structure of Centrosomal Proteins (2013) (22)
- XTACC3–XMAP215 association reveals an asymmetric interaction promoting microtubule elongation (2014) (19)
- Embryogenesis and aging of Drosophila melanogaster flown in the space shuttle (1986) (17)
- Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment (2017) (17)
- From motion to spindle checkpoint activity (2001) (15)
- A dominant negative approach for functional studies of the kinesin II complex. (2001) (14)
- The human sperm basal body is a complex centrosome important for embryo preimplantation development (2021) (14)
- The chaperonin CCT controls T cell receptor–driven 3D configuration of centrioles (2020) (13)
- The sequential activation of the mitotic microtubule assembly pathways favors bipolar spindle formation (2016) (12)
- Characterization of the TPX 2 Domains Involved in Microtubule Nucleation and Spindle Assembly in Xenopus Egg Extracts (2004) (11)
- Insights of the tubulin code in gametes and embryos: from basic research to potential clinical applications in humans†. (2018) (10)
- The chromosomal passenger complex takes center stage during mitosis. (2004) (9)
- From meiosis to mitosis – the sperm centrosome defines the kinetics of spindle assembly after fertilization in Xenopus (2016) (7)
- The C-terminal domain of TPX2 is made of alpha-helical tandem repeats (2016) (7)
- Microtubule nucleation during central spindle assembly requires NEDD1 phosphorylation on serine 405 by Aurora A (2019) (6)
- Aurora A: Working from dawn to dusk in mitosis (2014) (6)
- DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis (2019) (4)
- Proteomic Profiling of Microtubule Self-organization in M-phase* (2018) (4)
- Aurora-A regulates MCRS1 function during mitosis (2016) (4)
- Allosteric inhibition of Aurora-A kinase by a synthetic VNAR nanobody (2016) (3)
- Detection and Quantification of Protein–Microtubules Interactions Using Green Fluorescent Protein Photoconversion (2006) (3)
- Views from a continent in flux (2019) (3)
- Microgravity effects on insect development and aging (1989) (3)
- In vitro Assays for Mitotic Spindle Assembly and Function (2006) (3)
- Insects as test systems for assessing the potential role of microgravity in biological development and evolution. (1989) (3)
- Modeling the regulation of the bithorax complex in Drosophila melanogaster: the phenotypic effects of Ubx, abd-A and Abd-B heterozygotic larvae, and a homozygous Ubx- abd A hybrid gene. (1989) (3)
- Autosomal recessive variants in TUBGCP2 alter the γ-tubulin ring complex leading to neurodevelopmental disease (2020) (3)
- A giant leap for womankind (2019) (2)
- Dissecting the role of Aurora A during spindle assembly (2013) (2)
- Microtubule Organization in Mitotic Cells (2016) (2)
- Supplemental Data Kinesin II Mediates Vg 1 mRNA Transport in Xenopus Oocytes (2004) (2)
- The use of dominant negative mutants to study the function of mitotic motors in the in vitro spindle assembly assay in Xenopus egg extracts. (2001) (2)
- Functional Analysis of Human Pathological Semen Samples in an Oocyte Cytoplasmic Ex Vivo System (2018) (1)
- NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis (2022) (1)
- Report Nek 9 Phosphorylation of NEDD 1 / GCP-WD Contributes to Plk 1 Control of g-Tubulin Recruitment to the Mitotic Centrosome (2013) (1)
- Analysis of the Involvement of the Terrestrial Space Radiation in the Microgravity Effects on Drosophila Melanogaster Development and Aging (1988) (1)
- Only one spindle, if you please ... (2006) (1)
- Quantitative analysis of ventral denticular patterns of Drosophila melanogaster larvae and the regulation of the bithorax complex. (1989) (1)
- Understanding the Organization of Cell Metabolism in Early Embryonic Systems: Developmental Implications (1986) (1)
- How to design, implement and follow-up a Gender Equality Plan (2019) (0)
- Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11 (2022) (0)
- Gender stereotype and the scientific career of women: Evidence from biomedical research centers (2020) (0)
- S1 nuclease-sensitive sites in the bithoraxoid region of the Drosophila Ultrabithorax gene. (1993) (0)
- DnaJB6 is a RanGTPdependent microtubule Organization during mitosis (2019) (0)
- DnaJB6 is a RanGTP-regulated protein involved in dynein-dependent microtubule organization during mitosis (2019) (0)
- Mapping of key determinants for TACC3 binding to Aurora-A. (2015) (0)
- From meiosis to mitosis – the sperm centrosome defines the kinetics of spindle assembly after fertilization in Xenopus (2016) (0)
- Unveiling of a new role for DPF3 protein in cancer biology (2017) (0)
- Functional Analysis of Human Pathological Semen Samples in an Oocyte Cytoplasmic Ex Vivo System (2018) (0)
- [The possible role of cellular proto-oncogenes in early embryonic development]. (1983) (0)
- --N ttur-- w ssenschaften Embryogenesis and Aging of Drosophila melanogaster Flown in the Space Shuttle Preliminary Analysis of Experiment Fly 15 (0)
- Twenty years of cell-cycle conferences in Roscoff (2008) (0)
- MCRS1 modulates the heterogeneity of microtubule minus-end morphologies in mitotic spindles (2022) (0)
- A novel MAP involved in spindle pole organization. (2000) (0)
- O-171 Altered meiotic spindle morphology and composition in in vitro matured oocytes (2021) (0)
- Isabelle Vernos: motoring around the mitotic spindle. (2010) (0)
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