Joseph A. Beavo

Q: What Schools Are Affiliated With Joseph A. Beavo

Joseph A. Beavo is affiliated with the following schools: Ludwig Maximilian University of Munich, University of California, Davis, University of Tübingen, University of Washington, Central University of Venezuela

Joseph A. Beavo's AcademicInfluence.com Rankings

Joseph A. Beavo

Medical

#1404

World Rank

#1740

Historical Rank

Pharmacology

#114

World Rank

#146

Historical Rank

medical Degrees

Download Badge

Medical

Joseph A. Beavo's Degrees

PhD Pharmacology University of Washington
Bachelors Pharmacy University of Washington

Why Is Joseph A. Beavo Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Joseph A. Beavo's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. (1995) (1671)
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use (2006) (1630)
Phosphorylation-dephosphorylation of enzymes. (1979) (1615)
Foxp3-dependent programme of regulatory T-cell differentiation (2007) (1146)
Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. (2007) (1116)
Cyclic nucleotide research — still expanding after half a century (2002) (850)
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. (1990) (838)
Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. (2000) (767)
Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function (2003) (513)
Effects of xanthine derivatives on lipolysis and on adenosine 3',5'-monophosphate phosphodiesterase activity. (1970) (461)
Multiple cyclic nucleotide phosphodiesterases. (1994) (455)
Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. (1975) (416)
Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A. (2000) (348)
Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A. (1999) (346)
[43] Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle (1974) (337)
A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. (1997) (298)
Identification and Characterization of a Novel Family of Cyclic Nucleotide Phosphodiesterases* (1998) (280)
Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. (1998) (272)
Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues. (1982) (270)
CD3- and CD28-dependent induction of PDE7 required for T cell activation. (1999) (267)
Hydrolysis of cyclic guanosine and adenosine 3',5'-monophosphates by rat and bovine tissues. (1970) (264)
Leptin inhibits insulin secretion by activation of phosphodiesterase 3B. (1998) (260)
The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding (2002) (254)
Leptin Induces Insulin-like Signaling That Antagonizes cAMP Elevation by Glucagon in Hepatocytes* (2000) (249)
Stimulation of adenosine 3',5'-monophosphate hydrolysis by guanosine 3',5'-monophosphate. (1971) (247)
Cyclic nucleotide analogs as probes of signaling pathways (2008) (232)
PDE5 is converted to an activated state upon cGMP binding to the GAF A domain (2003) (231)
Characterization of a bovine cone photoreceptor phosphodiesterase purified by cyclic GMP-sepharose chromatography. (1988) (222)
Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs. (1986) (217)
Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase. (1998) (216)
Regulation of cGMP-specific Phosphodiesterase (PDE5) Phosphorylation in Smooth Muscle Cells* (2002) (213)
Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase. (1977) (211)
Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae. (1993) (204)
Upregulation of Phosphodiesterase 1A1 Expression Is Associated With the Development of Nitrate Tolerance (2001) (200)
Activation of protein kinase by physiological concentrations of cyclic AMP. (1974) (199)
High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. (1991) (199)
Phosphodiesterase type 5: expanding roles in cardiovascular regulation. (2007) (196)
Phosphorylation and Inhibition of Olfactory Adenylyl Cyclase by CaM Kinase II in Neurons a Mechanism for Attenuation of Olfactory Signals (1998) (190)
Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons. (1995) (174)
The Calmodulin-dependent Phosphodiesterase Gene PDE1C Encodes Several Functionally Different Splice Variants in a Tissue-specific Manner* (1996) (166)
Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy (2010) (159)
Calcium/calmodulin-activated phosphodiesterase expressed in olfactory receptor neurons (1992) (159)
Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases. (1990) (158)
GAF domains: two-billion-year-old molecular switches that bind cyclic nucleotides. (2002) (147)
Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype. (1997) (143)
Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase. (2000) (142)
Cyclic Nucleotide Phosphodiesterases in Health and Disease (2006) (141)
Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs). (1999) (141)
Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B. (1997) (141)
Inhibition and stimulation of photoreceptor phosphodiesterases by dipyridamole and M&B 22,948. (1989) (139)
Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP. (1992) (135)
Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy (2012) (134)
Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants. (1996) (133)
Isolation and Characterization of cDNAs Corresponding to Two Human Calcium, Calmodulin-regulated, 3′,5′-Cyclic Nucleotide Phosphodiesterases (*) (1996) (133)
Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase. (1997) (132)
Cyclic nucleotide phosphodiesterases : structure, regulation and drug action (1990) (130)
Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets. (1988) (129)
Cyclic Nucleotide Phosphodiesterase 1C Promotes Human Arterial Smooth Muscle Cell Proliferation (2002) (127)
Identification of Inhibitory and Calmodulin-binding Domains of the PDE1A1 and PDE1A2 Calmodulin-stimulated Cyclic Nucleotide Phosphodiesterases (*) (1995) (123)
cGMP is tightly bound to bovine retinal rod phosphodiesterase. (1989) (123)
T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3 (2001) (116)
Identification and properties of cyclic nucleotide phosphodiesterases (1982) (116)
Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. (1986) (115)
A-Kinase Anchoring Proteins Interact with Phosphodiesterases in T Lymphocyte Cell Lines1 (2004) (108)
Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. Identification and distribution of isozyme variants. (1991) (104)
Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes (2010) (102)
cGMP phosphodiesterase in rod and cone outer segments of the retina. (1985) (101)
THE FORMATION AND METABOLISM OF CYCLIC GMP * (1971) (101)
Differential Regulation of Endothelial Cell Permeability by cGMP via Phosphodiesterases 2 and 3 (2007) (101)
Solubilization of Membrane-bound Rod Phosphodiesterase by the Rod Phosphodiesterase Recombinant δ Subunit* (1996) (97)
Multiple isozymes of cyclic nucleotide phosphodiesterase. (1988) (96)
An Essential Aspartic Acid at Each of Two Allosteric cGMP-binding Sites of a cGMP-specific Phosphodiesterase (*) (1995) (95)
Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms (2006) (94)
Developmental changes in lung cGMP phosphodiesterase-5 activity, protein, and message. (1998) (94)
Individual Cerebellar Purkinje Cells Express Different cGMP Phosphodiesterases (PDEs): In Vivo Phosphorylation of cGMP-Specific PDE (PDE5) as an Indicator of cGMP-dependent protein kinase (PKG) Activation (2003) (92)
Modulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A (2006) (88)
Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes. (2010) (88)
Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerization. (2005) (87)
The High-Affinity cAMP-Specific Phosphodiesterase 8B Controls Steroidogenesis in the Mouse Adrenal Gland (2011) (83)
Cloning and characterization of two splice variants of human phosphodiesterase 11A. (2000) (83)
The mechanism of activation of bovine skeletal muscle protein kinase by adenosine 3':5'-monophosphate. (1980) (83)
Molecular Determinants for Cyclic Nucleotide Binding to the Regulatory Domains of Phosphodiesterase 2A* (2004) (83)
Molecular cloning of a cDNA encoding the "61-kDa" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms. (1993) (82)
Cyclic GMP and regulation of cyclic nucleotide hydrolysis. (1994) (82)
A soluble form of bovine rod photoreceptor phosphodiesterase has a novel 15-kDa subunit. (1989) (79)
Immunochemical characterization of the distinct monocyte cyclic AMP-phosphodiesterase from patients with atopic dermatitis. (1993) (77)
Cloning and localization of the cGMP-specific phosphodiesterase type 9 in the rat brain (2002) (76)
Purification of two calcium/calmodulin-dependent forms of cyclic nucleotide phosphodiesterase by using conformation-specific monoclonal antibody chromatography. (1982) (73)
Stoichiometry of cAMP and 1,N6-etheno-cAMP binding to protein kinase. (1980) (73)
Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle. (1974) (72)
Immunological identification of the major platelet low-Km cAMP phosphodiesterase: probable target for anti-thrombotic agents. (1986) (72)
Downregulation of Fasting-Induced cAMP Response Element-Mediated Gene Induction by Leptin in Neuropeptide Y Neurons of the Arcuate Nucleus (2001) (71)
Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain. (1991) (71)
Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression. (2004) (70)
Structure and function studies of the cGMP-stimulated phosphodiesterase. (1991) (70)
cAMP-Specific Phosphodiesterases 8A and 8B, Essential Regulators of Leydig Cell Steroidogenesis (2012) (68)
Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation. (2005) (67)
Rosiglitazone Inhibits Acyl-CoA Synthetase Activity and Fatty Acid Partitioning to Diacylglycerol and Triacylglycerol via a Peroxisome Proliferator–Activated Receptor-γ–Independent Mechanism in Human Arterial Smooth Muscle Cells and Macrophages (2007) (67)
Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages (2009) (65)
Specific localized expression of cGMP PDEs in Purkinje neurons and macrophages (2004) (64)
Characterization of cyclic nucleotide phosphodiesterases with cyclic GMP analogs: topology of the catalytic domains. (1995) (64)
EFFECTS OF PHOSPHODIESTERASE INHIBITORS ON CYCLIC AMP LEVELS AND ON LIPOLYSIS * (1971) (64)
Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1. (1997) (63)
Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis (2014) (62)
Immunofluorescent localization of cyclic nucleotide-dependent protein kinases on the mitotic apparatus of cultured cells (1980) (62)
Molecular cloning of cDNA encoding a "63"-kDa calmodulin-stimulated phosphodiesterase from bovine brain. (1992) (62)
Binding of the delta subunit to rod phosphodiesterase catalytic subunits requires methylated, prenylated C-termini of the catalytic subunits. (2000) (61)
cGMP Binding to Noncatalytic Sites on Mammalian Rod Photoreceptor Phosphodiesterase Is Regulated by Binding of Its γ and δ Subunits* (1999) (61)
Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei (2002) (60)
Identification, quantitation, and cellular localization of PDE1 calmodulin-stimulated cyclic nucleotide phosphodiesterases. (1998) (58)
Molecular Determinants of cGMP Binding to Chicken Cone Photoreceptor Phosphodiesterase* (2004) (58)
Turning on cGMP-dependent pathways to treat cardiac dysfunctions: boom, bust, and beyond. (2014) (58)
Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications. (1996) (58)
The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis. (2011) (55)
Mechanisms of control for cAMP-dependent protein kinase from skeletal muscle. (1975) (55)
Differential recognition of calmodulin-enzyme complexes by a conformation-specific anti-calmodulin monoclonal antibody. (1986) (55)
Phosphorylation of the 61-kDa calmodulin-stimulated cyclic nucleotide phosphodiesterase at serine 120 reduces its affinity for calmodulin. (1994) (54)
Purification of rabbit skeletal muscle protein kinase regulatory subunit using cyclic adenosine-3':5'-monophosphate affinity chromatography. (1975) (54)
Amino acid sequence of the cyclic GMP stimulated cyclic nucleotide phosphodiesterase from bovine heart. (1990) (54)
Phosphodiesterase-8A binds to and regulates Raf-1 kinase (2013) (50)
Regulation and function of cyclic nucleotides. (1992) (50)
Differential inhibition of cardiac cyclic nucleotide phosphodiesterase isozymes by cardiotonic drugs. (1986) (50)
Direct photolabeling of the cGMP-stimulated cyclic nucleotide phosphodiesterase. (1989) (46)
The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change*♦ (2008) (45)
Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: a unified nomenclature. (2006) (44)
Cyclic nucleotide signaling mechanisms in trypanosomes: possible targets for therapeutic agents. (2007) (44)
The cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites. (2005) (42)
The GAFa Domains of Rod cGMP-phosphodiesterase 6 Determine the Selectivity of the Enzyme Dimerization* (2003) (42)
Kaempferia parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low affinity PDE5 inhibitors. (2011) (42)
Cyclic Nucleotides Promote Monocyte Differentiation Toward a DC-SIGN+ (CD209) Intermediate Cell and Impair Differentiation into Dendritic Cells 1 (2003) (41)
Infection of CD4+ Memory T Cells by HIV-1 Requires Expression of Phosphodiesterase 41 (2000) (40)
Sequence comparison of the 63-, 61-, and 59-kDa calmodulin-dependent cyclic nucleotide phosphodiesterases. (1991) (40)
19 Recent advances in the study of Ca2+/CaM-activated phosphodiesterases (1997) (39)
Immunologic characterization of the photoreceptor outer segment cyclic GMP phosphodiesterase. (1984) (39)
Characterization of cyclic nucleotide phosphodiesterases with cyclic AMP analogs: topology of the catalytic sites and comparison with other cyclic AMP-binding proteins. (1995) (39)
Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis (2016) (37)
Isolation and characterization of a dual-substrate phosphodiesterase gene family : PDE 10 A (1999) (37)
Cyclic AMP-Dependent Protein Phosphorylation (1982) (37)
Identification of cGMP-stimulated cyclic nucleotide phosphodiesterase in lung tissue with monoclonal antibodies. (1982) (35)
Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5 (2008) (35)
PDE3 and PDE4 Isozyme-Selective Inhibitors Are Both Required for Synergistic Activation of Brown Adipose Tissue (2013) (35)
Regulation of cAMP metabolism in mouse parotid gland by cGMP and calcium. (1990) (34)
Affinities of bovine photoreceptor cGMP phosphodiesterases for rod and cone inhibitory subunits (1993) (34)
Reversibility of adenosine 3':5'-monophosphate-dependent protein kinase reactions. (1975) (34)
Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene. (1998) (34)
SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP (2016) (33)
Binding of adenosine 3',5'-monophosphate dependent protein kinase regulatory subunit to immobilized cyclic nucleotide derivatives. (1976) (33)
Trypanosome Cyclic Nucleotide Phosphodiesterase 2B Binds cAMP through Its GAF-A Domain* (2005) (33)
Radioimmunoassay of the regulatory subunit of type I cAMP-dependent protein kinase. (1979) (32)
Inactivation of Pde8b enhances memory, motor performance, and protects against age‐induced motor coordination decay (2012) (31)
Regulation of endothelial barrier function by cyclic nucleotides: the role of phosphodiesterases. (2011) (31)
Compartmentalization of cyclic nucleotides and cyclic AMP-dependent protein kinases in rat liver: immunocytochemical demonstration. (1978) (30)
Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics. (2016) (29)
The immunofluorescent localization of regulatory and catalytic subunits of cyclic AMP-dependent protein kinase in neuronal and glial cell types of the central nervous system (1981) (29)
Alteration of the regulatory subunit of type 1 cAMP-dependent protein kinase in mutant Y1 adrenal cells resistant to 8-bromoadenosine 3':5'-monophosphate. (1982) (28)
Identification of a New Variant of PDE1A Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase Expressed in Mouse Sperm1 (2005) (28)
PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte. (2006) (28)
A Yeast-Based Chemical Screen Identifies a PDE Inhibitor That Elevates Steroidogenesis in Mouse Leydig Cells via PDE8 and PDE4 Inhibition (2013) (28)
Multiplicity within cyclic nucleotide phosphodiesterases. (1996) (27)
Characterization of a novel cAMP-binding, cAMP-specific cyclic nucleotide phosphodiesterase (TcrPDEB1) from Trypanosoma cruzi. (2006) (27)
Evaluation of the therapeutic utility of phosphodiesterase 5A inhibition in the mdx mouse model of duchenne muscular dystrophy. (2011) (27)
Regulation of Adrenal Steroidogenesis by the High-affinity Phosphodiesterase 8 Family (2012) (27)
Recent advances in the study of Ca2+/CaM-activated phosphodiesterases: expression and physiological functions. (1997) (26)
Cyclic Nucleotide Phosphodiesterase Superfamily (2006) (25)
Regulation and function of cyclic nucleotides (1992) (24)
Cyclic nucleotide phosphodiesterases (2008) (23)
Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells (2017) (22)
Synthetic peptides based on the calmodulin-binding domain of myosin light chain kinase inhibit activation of other calmodulin-dependent enzymes. (1988) (22)
Intact cell and cell-free phosphorylation and concomitant activation of a low Km, cAMP phosphodiesterase found in human platelets. (1986) (20)
Molecular Cloning of a cDNA Encoding the "61-kDa" Calmodulin- stimulated Cyclic Nucleotide Phosphodiesterase (1993) (20)
Hormonal effects on the immunocytochemical location of 3',5'-cyclic adenosine monophosphate-dependent protein kinase in rat tissues. (1981) (19)
Purification of cyclic nucleotide receptor proteins by cyclic nucleotide affinity chromatography. (1979) (18)
cGMP inhibition of heart phosphodiesterase: is it clinically relevant? (1995) (17)
Purification of calmodulin-stimulated cyclic nucleotide phosphodiesterase by monoclonal antibody affinity chromatography. (1988) (16)
Cloning and characterization of two splice variants of human phosphodiesterase 11 A (2000) (15)
Cyclic nucleotides and phosphodiesterases in monocytic differentiation. (2011) (15)
cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits. (1999) (15)
The role of protein phosphorylation in the regulation of cyclic nucleotide phosphodiesterases (1993) (14)
Enzyme assays for cGMP hydrolyzing phosphodiesterases. (2013) (14)
Immunocytochemical localization of cyclic guanosine monophosphate-dependent protein kinase in endocrine tissues. (1981) (13)
Monoclonal antibodies as structural probes of surface residues in the regulatory subunit of cAMP-dependent protein kinase II from porcine heart. (1983) (13)
Cyclic Nucleotide Phosphodiesterase 1 C Promotes Human Arterial Smooth Muscle Cell Proliferation (2002) (10)
Isolation and comparison of bovine heart cGMP-inhibited and cGMP-stimulated phosphodiesterases. (1988) (9)
Immunotitration analysis of the rod outer segment phosphodiesterase. (1984) (9)
Immunologic approaches to the study of cyclic nucleotide phosphodiesterases. (1984) (8)
Phosphodiesterase 8A, cAMP-specific (2012) (7)
5 – Cyclic Nucleotide Regulation by Calmodulin (1998) (7)
Purification and assay of bovine type 6 photoreceptor phosphodiesterase and its subunits. (2000) (6)
Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. (2019) (6)
The high affinity cAMP-specific phosphodiesterase 8 B ( PDE 8 B ) controls steroidogenesis in the mouse adrenal gland (2010) (6)
PHOSPHORYLATION DEPHOSPHORYLATIO N OF ENZYMES (1979) (5)
Biochemistry and Physiology of (2007) (5)
2491 – THE DISTRIBUTION OF CYCLIC NUCLEOTIDES (CN) AND THEIR PROTEIN KINASES IN TISSUES: AN IMMUNOCYTOCHEMICAL APPROACH (1978) (5)
Activation ofProtein KinasebyPhysiological Concentrations ofCyclic AMP (1974) (4)
The domain structure of the calmodulin-dependent phosphodiesterase isozymes. (1989) (4)
LOCALIZATION OF PDE5 IN MOUSE LUNG AND BRAIN AND CLONING OF TWO MOUSE PDE5 ISOFORMS (1996) (3)
STRUCTURE AND FUNCTION OF CALMODULIN-DEPENDENT PHOSPHODIESTERASE ISOZYMES (1987) (2)
Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy (2013) (2)
Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-Dependent Actions (2021) (2)
PDE 3 and PDE 4 Isozyme-Selective Inhibitors Are Both Required for Synergistic Activation of Brown Adipose Tissue s (2013) (2)
Modulation of adrenal steroidogenesis by c‐AMP specific phosphodiesterase 8 (2008) (2)
Microarray Cell Signaling Kit: A Unique Tool for Protein Expression Analysis (2004) (2)
Sildenafil Ameliorates Cardiomyopathy in mdx Mice (2009) (2)
Effect of Sildenafil on mdx Skeletal Muscle (2008) (2)
Cyclic nucleotide-binding GAF domains in phosphodiesterases and adenylyl cyclases (2010) (1)
Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy (2013) (1)
Phosphodiesterase 8A Modulates Lipolysis in Primary Brown Adipocytes (2009) (1)
Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 (2008) (1)
Cyclic nucleotide phosphodiesterases – 40 years of progress (2009) (1)
Role of phosphodiesterase 8A (PDE8A) in lipid metabolism in the liver (2008) (1)
Investigation of a low Km phosphodiesterase from cardiac muscle using monoclonal antibodies and phosphodiesterase inhibitors (1985) (1)
THE CALMODULIN-DEPENDENT PHOSPHODIESTERASE GENE PDE1C ENCODES SEVERAL FUNCTIONALLY DIFFERENT SPLICE VARIANTS IN A TISSUE SPECIFIC MANNER (1996) (1)
Celltransmissions The Newsletter for Cell Signaling and Neuroscience Research Functions and Pharmacological Inhibitors of Cyclic Nucleotide Phosphodiesterases (2004) (1)
Differential Regulation of Brown Adipose Tissue Activation by PDE3 and PDE4 (2012) (1)
Structural and Functional Characterization of Cyclic GMP-Stimulated Phosphodiesterases and Their Role in Intracellular Signal Transduction (1990) (1)
The Mechanism of Action of Cyclic AMP in the Activation of Phosphorylase Kinase (1972) (1)
Kaempferia Parviflora wall. Ex Baker: A Source of PDE5 Inhibitors (2013) (1)
Proliferation Cyclic Nucleotide Phosphodiesterase 1 C Promotes Human Arterial Smooth Muscle Cell (2002) (1)
Localization of guanylate cyclase-activating protein 2 in mammalian retinas (phototransductionyguanylate cyclaseyCa 21 -binding proteinsycone photoreceptors) (1997) (1)
Sequence homology and structure--function studies of the bovine cyclic-GMP-stimulated and retinal phosphodiesterases. (1992) (1)
Chapter 173 – Phosphodiesterase Families (2010) (1)
cGMP kinase I, cardiac hypertrophy and PDE inhibition (2011) (1)
The Structure of the GAF A Domain from Phosphodiesterase 6 C Reveals (2008) (1)
CHAPTER 207 – Cyclic Nucleotide-Binding Phosphodiesterase and Cyclase GAF Domains (2003) (1)
Radioimmunoassay of the regulatory subunit of type I cAMP-dependent protein kinase. (1979) (1)
T.P.5 Sildenafil (Viagra®) improves cardiac and diaphragm muscle function in the dystrophic mouse (2012) (0)
Structural and Biophysical Characterization of the GAF Domains from Phosphodiesterases 5 and 6 (2009) (0)
Life Cycles of TRYPANOSOMA BRUCEI and T. CRUZI (2007) (0)
Production and characterization of monoclonal antibodies to type II regulatory subunit of cyclic AMP dependent protein kinase. (1980) (0)
Reviewer List for 2004 (2004) (0)
PDE4 inhibitors can induce pro‐inflammatory chemokine expression in human macrophages (2009) (0)
Identification of multiple forms of photoreceptor outer segment phosphodiesterase (1984) (0)
CHAPTER 192 – Phosphodiesterase Families (2003) (0)
Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons ( cAMP / Ca 2 + / smell / tissue-specific expression ) (2005) (0)
Compartmentation of Cyclic Nucleotide Signaling in the Heart: The Role of Cyclic Nucleotide Phosphodiesterases Overview of PDEs and their Regulation Regulation of Phosphodiesterase 3 (PDE3) and Inducible cAMP Early Repressor in the Heart cAMP Specific Phosphodiesterase-4 Enzymes in the Cardiovascula (2007) (0)
Molecular targets for PDE inhibitor-mediated improvement of cardiac dysfunction in the mdx mouse? (2011) (0)
LOCALIZATION, REGULATION, AND FUNCTION OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES (1996) (0)
Utilization of a Monoclonal Antibody to Study in Vitro Phosphorylation of a Low Km Phosphodiesterase (1987) (0)
Phosphodiesterase (PDE) activity measured by micro‐isothermal calorimetry; a study of cyclic nucleotide analogues as substrates and inhibitors of PDEs1a, 1b, 1c, 2, 4, 5, 6, 8, 9, and 10 (2008) (0)
Mechanism of activation and inactivation of the cyclic amp dependent protein kinases (1981) (0)
Rosiglitazone Inhibits Acyl-CoA Synthetase Activity and Fatty Acid Partitioning to Diacylglycerol and Triacylglycerol via a PPAR γ-Independent Mechanism in Human Arterial Smooth Muscle Cells and Macrophages (2006) (0)
Sildenafil Ameliorates Skeletal Muscle Pathology in the mdx Mouse Model of Duchenne Muscular Dystrophy (2011) (0)
Molecular mechanism of cyclic nucleotide binding to the GAF domains of Phosphodiesterase 2A (2003) (0)
353 CYCLIC AMP HYDROLYZING, CYCLIC-GMP INHIBITED PHOSPHODIESTERASE (PDE3B) IS HIGHLY EXPRESSED IN BOVINE AND GECKO PHOTORECEPTORS (2005) (0)
A novel inhibitor of the T. brucei TbPDE2 cAMP phosphodiesterase family is a potent trypanocidal agent (2006) (0)
Differentiation into Dendritic Cells (CD209) Intermediate Cell and Impair + Differentiation Toward a DC-SIGN Cyclic Nucleotides Promote Monocyte (2003) (0)
Molecular cloning and ch human phosphodiesteras (2016) (0)
Effect of elevated cAMP on macrophage differentiation (2008) (0)
Chapter 3 The role of multiple isozymes in the regulation of cyclic nucleotide synthesis and degradation (1996) (0)
Disruption of the phosphodiesterase 8B (PDE8B) gene alters the hypothalamic‐pituitary‐adrenal (HPA) axis (2009) (0)
cGMP regulation of phosphodiesterases: structure and function (2003) (0)
Lines Phosphodiesterases in T Lymphocyte Cell A-Kinase Anchoring Proteins Interact with and (2004) (0)
Calmodulin sensitive cyclic nucleotide phosphodiesterase (pde) purification utilizing a conformation-specific monoclonal anti- body. Abstr. (1981) (0)
Acknowledgement to reviewers (2005) (0)
IDENTIFICATION OF A NEW PDE2A ISOFORM AND EXPRESSION OF PDE2 IN A SUBSET OF OLFACTORY NEURONS & GASTROINTESTINAL CELLS (1996) (0)
Screening procedures to identify G-proteins and other compounds that modulate phosphodiesterase (PDE) activity (2001) (0)
Regulation of cyclic nucleotide hydrolysis by cGMP (2005) (0)
Phosphorylation of cAMP hydrolyzing PDE (PDE3A) by cGMP-dependent protein kinase (PKG) in human platelets (2007) (0)
The Identification and Significance of Substructural Domains (1989) (0)
A1109 DIFFERENTIAL CONTROL OF PULMONARY PDE1 ISOTYPES IN AN EXPERIMENTAL PERINATAL PULMONARY HYPERTENSIVE MODEL (1997) (0)
PDE5 Site A: A Structural Analysis of cGMP Binding (2003) (0)
Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains (2002) (0)
Union cyclic GMP, materials specific to cyclic GMP phosphodiesterase and methods. (1994) (0)
A CaM-DEPENDENT PHOSPHODIESTERASE (PDE1C) IS INDUCED IN HUMAN ARTERIAL SMOOTH MUSCLE CELLS DURING TRANSITION FROM INTACT AORTA TO CELL CULTURE (1996) (0)
Cyclic GMP-binding, cyclic GMP-specific phosphodiesterasematerialer and Methods (1994) (0)
Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C (2008) (0)
Sildenafil ameliorates cardiomyopathy in dystrophin-null (mdx) mice (2009) (0)
Reply to Kass and Takimoto: Cardiac hypertrophy without cGKI and PDE5 in cardiac myocytes (2010) (0)
P124 Autosomal Dominant Striatal Degeneration is caused by a mutation in the phosphodiesterase 8B gene (2011) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Joseph A. Beavo?

Joseph A. Beavo is affiliated with the following schools: