Joel Anthony Huberman
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Joel Anthony Hubermanbiology Degrees
Biology
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Genetics
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#1277
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Molecular Biology
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#1681
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Biochemistry
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#1928
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Biology
Joel Anthony Huberman's Degrees
- Masters Biochemistry Stanford University
- Bachelors Biology University of California, Berkeley
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Why Is Joel Anthony Huberman Influential?
(Suggest an Edit or Addition)Joel Anthony Huberman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- On the mechanism of DNA replication in mammalian chromosomes. (1968) (867)
- Heterogeneity of eukaryotic replicons, replicon clusters, and replication foci (2000) (376)
- New views of the biochemistry of eucaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase α (1981) (355)
- The in vivo replication origin of the yeast 2μm plasmid (1987) (343)
- Organization of replication of ribosomal DNA in Saccharomyces cerevisiae. (1988) (329)
- [96] Isolation and characterization of chromosomal nucleoproteins (1968) (301)
- Eukaryotic chromosome replication. (1975) (294)
- Excision of Thymine Dimers and Other Mismatched Sequences by DNA Polymerase of Escherichia coli (1969) (259)
- Mammalian Mitochondrial DNA Replicates Bidirectionally from an Initiation Zone* (2003) (226)
- Non-random circular permutation of phage P22 DNA. (1974) (201)
- Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase. (1969) (180)
- Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins (1991) (167)
- Stimulation of T4 bacteriophage DNA polymerase by the protein product of T4 gene 32. (1971) (157)
- Early-replicating heterochromatin. (2003) (151)
- Regulation of replication timing in fission yeast (2001) (138)
- Close association of a DNA replication origin and an ARS element on chromosome III of the yeast, Saccharomyces cerevisiae. (1988) (135)
- Three ARS elements contribute to the ura4 replication origin region in the fission yeast, Schizosaccharomyces pombe. (1994) (132)
- The in vivo replication origin of the yeast 2 microns plasmid. (1987) (129)
- MCM2 is an independent predictor of survival in patients with non-small-cell lung cancer. (2001) (128)
- Autoradiography of chromosomal DNA fibers from Chinese hamster cells. (1966) (127)
- Large, complex modular structure of a fission yeast DNA replication origin (1996) (120)
- Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication. (1978) (118)
- Changes in the rate of DNA replication fork movement during S phase in mammalian cells. (1975) (115)
- DNA Replication Sites within Nuclei of Mammalian Cells (1973) (114)
- Effects of 2′,3′‐dideoxynucleosides on mammalian cells and viruses (1984) (114)
- Two-dimensional gel electrophoretic method for mapping DNA replicons (1988) (111)
- DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding Yeast (2007) (104)
- New beginnings in studies of eukaryotic DNA replication origins. (1989) (104)
- Apoptosis-like yeast cell death in response to DNA damage and replication defects. (2003) (104)
- Direction of DNA replication in mammalian cells. (1973) (99)
- Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer (2006) (96)
- HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues. (1998) (96)
- MCM2 - a promising marker for premalignant lesions of the lung: a cohort study (2001) (91)
- Apoptosis in budding yeast caused by defects in initiation of DNA replication (2005) (86)
- Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 Are Components of a Novel S-Phase Response Pathway to Alkylation Damage (2005) (84)
- Ribosomal DNA replication in the fission yeast, Schizosaccharomyces pombe. (1998) (84)
- A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway (2002) (84)
- Localization of a DNA replication origin and termination zone on chromosome III of Saccharomyces cerevisiae (1992) (77)
- Both DNA topoisomerases I and II relax 2 μm plasmid DNA in living yeast cells (1986) (74)
- Visualization of replicating mammalian and T4 bacteriophage DNA. (1968) (73)
- ISOLATION OF METAPHASE CHROMOSOMES FROM HELA CELLS (1966) (69)
- Multiple Orientation-Dependent, Synergistically Interacting, Similar Domains in the Ribosomal DNA Replication Origin of the Fission Yeast, Schizosaccharomyces pombe (1998) (69)
- Ambiguities in results obtained with 2D gel replicon mapping techniques. (1990) (67)
- Mapping of replication initiation sites in human ribosomal DNA by nascent-strand abundance analysis (1995) (65)
- An origin of replication and a centromere are both needed to establish a replicative plasmid in the yeast Yarrowia lipolytica (1997) (65)
- Asymmetric Okazaki piece synthesis during replication of simian virus 40 DNA in vivo (1977) (64)
- Studies of fractionated HeLa cell metaphase chromosomes: I. The chromosomal distribution of DNA complementary to 28 s and 18 s ribosomal RNA and to cytoplasmic messenger RNA (1967) (64)
- Structure of chromosome fibers and chromosomes. (1973) (58)
- Effects of inhibition of protein synthesis on DNA replication in cultured mammalian cells. (1977) (57)
- The two faces of higher eukaryotic DNA replication origins (1990) (57)
- pDblet, a stable autonomously replicating shuttle vector for Schizosaccharomyces pombe. (1995) (53)
- Identification, purification, and molecular cloning of autonomously replicating sequence-binding protein 1 from fission yeast Schizosaccharomyces pombe. (1996) (53)
- Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast (2006) (49)
- Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe. (1997) (46)
- Chromatin architectures at fission yeast transcriptional promoters and replication origins (2012) (42)
- Checkpoint independence of most DNA replication origins in fission yeast (2007) (41)
- Covalent attachment of RNA to nascent DNA in mammalian cells (1975) (41)
- Induction by Adozelesin and Hydroxyurea of Origin Recognition Complex-dependent DNA Damage and DNA Replication Checkpoints in Saccharomyces cerevisiae * (1999) (40)
- Electron microscopy of DNA polymerase bound to DNA. (1971) (39)
- DNA replication origins in animal cells: a question of context? (1994) (37)
- Enforcement of Late Replication Origin Firing by Clusters of Short G-rich DNA Sequences*♦ (2004) (37)
- Eukaryotic DNA replication: A complex picture partially clarified (1987) (34)
- Evidence for the attachment of RNA to pulse-labeled DNA in the slime mold, Physarum polycephalum. (1973) (33)
- In vitro HeLa cell DNA synthesis similarity to in vivo replication. (1977) (33)
- Influence of a replication enhancer on the hierarchy of origin efficiencies within a cluster of DNA replication origins. (1999) (33)
- Enzymatic synthesis of deoxyribonucleic acid. XXXV. A 3'-hydroxylribonucleotide binding site of Escherichia coli deoxyribonucleic acid polymerase. (1970) (32)
- Covalent linkage between RNA and nascent DNA in the slime mold, Physarum polycephalum. (1975) (31)
- Discontinuous DNA synthesis in mammalian cells. (1974) (31)
- Roles for internal and flanking sequences in regulating the activity of mating-type-silencer-associated replication origins in Saccharomyces cerevisiae. (2001) (29)
- Checkpoint-Dependent Regulation of Origin Firing and Replication Fork Movement in Response to DNA Damage in Fission Yeast (2008) (29)
- Prokaryotic and eukaryotic replicons (1995) (29)
- On the Slowing of S Phase in Response to DNA Damage in Fission Yeast* (2004) (26)
- Mapping replication origins, pause sites, and termini by neutral/alkaline two-dimensional gel electrophoresis. (1997) (26)
- In vitro HeLa cell DNA synthesis. II. Partial characterization of soluble factors stimulating nuclear dna synthesis. (1978) (26)
- Subnuclear systems for synthesis of simian virus 40 DNA in vitro. (1976) (24)
- Importance of measuring nucleic acid absorbance at 240 nm as well as at 260 and 280 nm. (1995) (24)
- Comparison of the two major ARS elements of the ura4 replication origin region with other ARS elements in the fission yeast, Schizosaccharomyces pombe (1994) (23)
- Identification and characterization of a complex chromosomal replication origin in Schizosaccharomyces pombe. (1992) (22)
- DNA damage and replication checkpoints in the fission yeast, Schizosaccharomyces pombe. (1999) (22)
- Association of enzymes with replicating and nonreplicating simian virus 40 chromosomes. (1979) (21)
- Multiple redundant sequence elements within the fission yeast ura4 replication origin enhancer (2001) (21)
- Isolation and initial characterization of residual nuclear structures from yeast. (1984) (20)
- Techniques of autoradiography. 3rd edition, revised By A. W. Rogers. Amsterdam, New York, Oxford: Elsevier/North-Holland. 429 pp. $59.00 (1980) (17)
- Isolation, Characterization, and Molecular Cloning of a Protein (Abp2) That Binds to a Schizosaccharomyces pombe Origin of Replication (ars3002) (1998) (17)
- DNA synthesis by partially purified replicating simian virus 40 chromosomes. (1977) (17)
- Genetic methods for characterizing the cis-acting components of yeast DNA replication origins. (1999) (16)
- Both DNA topoisomerases I and II relax 2 micron plasmid DNA in living yeast cells. (1986) (16)
- Preparation of large quantities of separated strands from simian virus 40 DNA restriction fragments by low-temperature low-salt agarose gel electrophoresis. (1977) (15)
- Prognostic significance of MCM 2 , Ki-67 and gelsolin in non-small cell lung cancer (2006) (12)
- Two-dimensional analysis of proteins sedimenting with simian virus 40 chromosomes (1980) (12)
- Yeast and mammalian replication intermediates migrate similarly in two-dimensional gels (1995) (12)
- Method of mapping DNA replication origins (1985) (11)
- Checkpoint effects and telomere amplification during DNA re-replication in fission yeast (2007) (11)
- Centromeric DNA from Saccharomyces uvarum is functional in Saccharomyces cerevisiae (1986) (10)
- Integrity of chromatin and replicating DNA in nuclei released from fission yeast by semi-automated grinding in liquid nitrogen (2011) (10)
- Choosing a Place to Begin (1998) (10)
- Characterization of DNA sequences associated with residual nuclei of Saccharomyces cerevisiae. (1986) (9)
- Topological complexity of SV40 minichromosomes. (1996) (9)
- A licence to replicate (1995) (8)
- Both parental deoxyribonucleic acid strands at each replication fork of replicating simian virus 40 chromosomes are cut by a single-strand-specific endonuclease. (1982) (7)
- DNA Replication in S. pombe (2004) (7)
- Restriction fragment primed ΦX174 single-stranded DNA as template for DNA polymerases α and β. Detection and partial purification of a polymerase α stimulating factor (1980) (7)
- FROM CHINESE HAMSTER CELLS (2016) (6)
- Directions of DNA Replication in Yeast and Mammalian Cells (1992) (5)
- Cell cycle control of initiation of eukaryotic DNA replication (1991) (5)
- A tale of two functions (1994) (5)
- Identification and characterization of a complex chromosomal replication origin inSchizosaccharomyces pombe (2006) (5)
- DNA replication, the cell cycle and genome stability. (2003) (5)
- Cell cycle control of S phase: A comparison of two yeasts (1996) (4)
- Identification of two telomere-proximal fission yeast DNA replication origins constrained by nearby cis-acting sequences to replicate in late S phase (2012) (4)
- Motifs in Schizosaccharomyces pombe ars3002 important for replication origin activity in Saccharomyces cerevisiae. (2003) (3)
- Studies on Replicating Simian Virus 40 Chromosomes: Association with Thymidine Kinase (1978) (3)
- Studies on the penetration of mammalian cells by deoxyribonucleoside‐5′‐phosphates (1979) (3)
- In vitro DNA synthesis by an alpha-like DNA polymerase bound to replicating simian virus 40 chromosomes (1983) (3)
- Organization of replication of ribosomal DNA in Saccharomyces cerevisiae (1988) (2)
- Subtle interactions between heterochromatin and DNA replication timing (2011) (2)
- Quest's end and questions' beginning (1992) (2)
- 17 Responses to Aberrant DNA Replication and DNA Damage in Yeasts (2006) (2)
- DNA replication. Choosing a place to begin. (1998) (2)
- Antitumor Drugs and Yeast Cell Cycle Checkpoints (1997) (1)
- DNA topoisomerases in eukaryotes (1985) (1)
- Faculty Opinions recommendation of Genome-wide identification and characterization of replication origins by deep sequencing. (2012) (1)
- Identification, purification, and molecular cloning of autonomously replicating sequence-binding protein 1 from fission yeast Schizosaccharomyces pombe (DNA-binding proteinyCENP-B) (1996) (1)
- WORKSHOP SUMMARY: RNA Priming (1980) (0)
- MCM2: Test of utility as a molecular marker in advanced-stage oropharyngeal carcinoma. (2004) (0)
- Faculty Opinions recommendation of Rif1 is a global regulator of timing of replication origin firing in fission yeast. (2012) (0)
- Clinicopathological correlation of expression of MCM2 in patients with non-small cell lung cancer (NSCLC) (2000) (0)
- Faculty Opinions recommendation of Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure. (2010) (0)
- Faculty Opinions recommendation of Genome-wide characterization of fission yeast DNA replication origins. (2006) (0)
- My unusually dedicated mentor. (2002) (0)
- I S O L a T I O N of M E T a P H a S E Cultivation of Cells (0)
- Faculty Opinions recommendation of Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae. (2008) (0)
- Education: Doctor of Philosophy, Dept. of Biological Sciences, SUNY at Buffalo. (2012) (0)
- DNA Replication, the Nuclear Membrane, and Okazaki Fragments in Eukaryotic Organisms (1974) (0)
- Faculty Opinions recommendation of Promiscuous initiation on mammalian chromosomal DNA templates and its possible suppression by transcription. (2007) (0)
- Faculty Opinions recommendation of Non-transcriptional control of DNA replication by c-Myc. (2007) (0)
- Faculty Opinions recommendation of Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins. (2006) (0)
- Faculty Opinions recommendation of DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication. (2007) (0)
- Chromosoma Focus (1996) (0)
- Faculty Opinions recommendation of Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast. (2007) (0)
- Faculty Opinions recommendation of Identification of mutations that decrease the stability of a fragment of Saccharomyces cerevisiae chromosome III lacking efficient replicators. (2007) (0)
- Faculty Opinions recommendation of The Hsk1(Cdc7) replication kinase regulates origin efficiency. (2008) (0)
- The Many Faces of Eukaryotic Replication Origins (2017) (0)
- Faculty Opinions recommendation of Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae. (2006) (0)
- Faculty Opinions recommendation of SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. (2008) (0)
- Faculty Opinions recommendation of Global reorganization of replication domains during embryonic stem cell differentiation. (2008) (0)
- Faculty Opinions recommendation of Regulation of replication fork progression through histone supply and demand. (2008) (0)
- Faculty Opinions recommendation of Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA. (2008) (0)
- Faculty Opinions recommendation of Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation. (2006) (0)
- Studies on the Structure and Function of Mammalian Chromosomes (1968) (0)
- Faculty Opinions recommendation of Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase. (2006) (0)
- Faculty Opinions recommendation of Isolating apparently pure libraries of replication origins from complex genomes. (2006) (0)
- DNA metabolism. A tale of two functions. (1994) (0)
- Faculty Opinions recommendation of DNA replication origins fire stochastically in fission yeast. (2006) (0)
- Faculty Opinions recommendation of Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. (2006) (0)
- Faculty Opinions recommendation of Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast. (2006) (0)
- Faculty Opinions recommendation of Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication. (2006) (0)
- Faculty Opinions recommendation of HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast. (2007) (0)
- Cell cycle. A licence to replicate. (1995) (0)
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