Joseph Beene Bolen

Joseph Beene Bolen's AcademicInfluence.com Rankings

Joseph Beene Bolen

Philosophy

#9029

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#12522

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Logic

#6031

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#7508

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philosophy Degrees

Joseph Beene Bolen

Biology

#12347

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#15818

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Cell Biology

#648

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#662

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Immunology

#822

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#845

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Molecular Biology

#1991

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#2023

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biology Degrees

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Philosophy
Biology

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Joseph Beene Bolen's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56 lck (1988) (1173)
Syk tyrosine kinase required for mouse viability and B-cell development (1995) (664)
Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck (1989) (609)
Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases (1992) (479)
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase (2007) (407)
Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. (1991) (398)
Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases. (1991) (376)
Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. (1995) (349)
Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn. (1993) (306)
Activation of pp60c-src protein kinase activity in human colon carcinoma. (1987) (287)
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation (1984) (276)
Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases (1995) (274)
Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays (2011) (259)
Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. (1994) (258)
Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells (1995) (236)
A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen (1998) (226)
Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3. (1994) (223)
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. (1993) (219)
Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta (1993) (219)
Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. (1994) (212)
Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues. (1986) (211)
Granulocyte macrophage‐colony stimulating factor stimulates both association and activation of phosphoinositide 3OH‐kinase and src‐related tyrosine kinase(s) in human myeloid derived cells. (1993) (199)
Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. (1998) (198)
The Src family of tyrosine protein kinases in hemopoietic signal transduction (1992) (190)
Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells. (1994) (187)
Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase. (1993) (183)
Inability of CD8α′polypeptides to associate with p56 lck correlates with impaired function in vitro and lack of expression in vivo (1989) (178)
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. (1991) (178)
Nonreceptor tyrosine protein kinases. (1993) (177)
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. (1997) (176)
B Cell Antigen Receptor-Induced Activation of Akt Promotes B Cell Survival and Is Dependent on Syk Kinase1 (2000) (168)
RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells (1996) (162)
Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation (1988) (159)
Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways (1989) (159)
Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1 (1999) (158)
Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase (1995) (156)
Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen. (1984) (156)
Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus (1991) (154)
An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases (1992) (153)
ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction. (1994) (151)
Leukocyte protein tyrosine kinases: potential targets for drug discovery. (1997) (151)
Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif (1994) (149)
Endogenous Reactive Oxygen Intermediates Activate Tyrosine Kinases in Human Neutrophils (*) (1996) (146)
The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. (1996) (139)
The Product of the Herpesvirus saimiri Open Reading Frame 1 (Tip) Interacts with T Cell-specific Kinase p56lck in Transformed Cells (*) (1995) (129)
Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI (1995) (129)
Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking. (1992) (121)
Exposure of B-lineage Lymphoid Cells to Low Energy Electromagnetic Fields Stimulates Lyn Kinase (*) (1995) (119)
Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20 (1995) (118)
Protein tyrosine kinases in the initiation of antigen receptor signaling. (1995) (118)
Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny. (1993) (116)
Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement. (1994) (113)
Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family. (1994) (111)
Regulatory factors that determine growth and phenotype of normal human melanocytes. (1988) (105)
Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product. (1985) (105)
HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. (1996) (103)
Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes (1989) (97)
Safety Evaluation of Lipid Nanoparticle–Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey (2018) (94)
Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. (1987) (93)
Transcriptional analysis of the PTEN/MMAC1 pseudogene, ΨPTEN (1999) (92)
Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924. (2012) (92)
The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2 (1996) (91)
src-related tyrosine protein kinases as signaling components in hematopoietic cells. (1990) (91)
Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells. (1987) (89)
Identification of a novel neuronal C-SRC exon expressed in human brain (1990) (88)
Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C. (1988) (87)
TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck. (1996) (87)
Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex. (1997) (86)
Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1. (1992) (82)
Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction. (1994) (82)
Specific Association of Tyrosine-phosphorylated c-Cbl with Fyn Tyrosine Kinase in T Cells* (1996) (82)
No T-cell tyrosine protein kinase signalling or calcium mobilization after CD4 association with HIV-1 or HIV-1 gp120 (1990) (79)
Bicyclic compounds as ring-constrained inhibitors of protein-tyrosine kinase p56lck. (1993) (77)
Reconstitution of Btk Signaling by the Atypical Tec Family Tyrosine Kinases Bmx and Txk* (1999) (76)
Expression and interactions of the Src family of tyrosine protein kinases in T lymphocytes. (1991) (75)
Association of Src-like protein tyrosine kinases with the CD2 cell surface molecule in rat T lymphocytes and natural killer cells (1992) (75)
Cross-linking of Fc gamma receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel. (1994) (73)
Tyrosine phosphorylation and association of Syk with Fc gamma RII in monocytic THP-1 cells. (1995) (71)
Selective Activation of T Cell Kinase p56lck by Herpesvirus saimiri Protein Tip (*) (1996) (71)
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells (2001) (70)
Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. (1996) (70)
Differences in the subpopulations of the structural proteins of polyoma virions and capsids: biological functions of the multiple VP1 species (1981) (69)
Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells (1989) (67)
Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1 (1989) (66)
MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors (2015) (66)
Signal transduction by the SRC family of tyrosine protein kinases in hemopoietic cells. (1991) (63)
Production and characterization of a monoclonal antibody that binds Reed-Sternberg cells. (1985) (63)
The src family of tyrosine protein kinases in hemopoietic signal transduction (1992) (61)
CD4, CD8 and the role of CD45 in T-cell activation. (1993) (58)
Expression of p60fyn in human platelets. (1990) (57)
Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45. (1994) (56)
The FcγRII Receptor Triggers pp125FAK Phosphorylation in Platelets* (1996) (55)
Tyrosine phosphorylation within the amino-terminal domain of pp60c-src molecules associated with polyoma virus middle-sized tumor antigen. (1985) (53)
The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity (2000) (52)
Effects of the tyrosine‐kinase inhibitor geldanamycin on ligand‐induced HER‐2/NEU activation, receptor expression and proliferation of HER‐2‐positive malignant cell lines (1997) (52)
Differential adsorption of polyoma virions and capsids to mouse kidney cells and guinea pig erythrocytes (1979) (51)
Ig alpha and Ig beta are functionally homologous to the signaling proteins of the T-cell receptor (1994) (49)
Interleukin-2-induced tyrosine phosphorylation of Shc proteins correlates with factor-dependent T cell proliferation. (1994) (48)
Identification of distinct populations of PI-3 kinase activity following T-cell activation. (1992) (47)
Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells. (1995) (45)
Regulation of pp60c-src synthesis by inducible RNA complementary to c-src mRNA in polyomavirus-transformed rat cells (1986) (44)
Interaction of p72 syk with the gand bSubunits of the High-Affinity Receptor for Immunoglobulin E, FcεRI (1995) (42)
Signal transduction by the cytoplasmic domains of Fc epsilon RI-gamma and TCR-zeta in rat basophilic leukemia cells. (1992) (41)
Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. (1989) (41)
Middle tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with pp60c-src (1985) (41)
A function for the lck proto-oncogene. (1989) (40)
Temporal Activation of Nontransmembrane Protein-tyrosine Kinases following Mast Cell FcεRI Engagement (*) (1995) (39)
Phosphonate-containing inhibitors of tyrosine-specific protein kinases. (1991) (39)
Analysis of pp60c‐src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells (1987) (37)
The Raf-1 serine-threonine kinase is a substrate for the p56lck protein tyrosine kinase in human T-cells. (1991) (35)
Syk Mutation in Jurkat E6-derived Clones Results in Lack of p72syk Expression (*) (1995) (35)
Molecular Cloning of Rodent p72Syk. (1995) (35)
Activation-dependent tyrosine phosphorylation of Fyn-associated proteins in T lymphocytes. (1994) (34)
Physical and Functional Interactions between Lyn and p34 Kinases in Irradiated Human B-cell Precursors (*) (1996) (34)
Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase (1999) (31)
Cross-linking of surface immunoglobulin activates src-related tyrosine kinases in WEHI 231 cells. (1992) (30)
Analysis of the c-src gene product structure, abundance, and protein kinase activity in human neuroblastoma and glioblastoma cells. (1987) (30)
Isolation and characterization of polyoma uncoating intermediates from the nuclei of infected mouse cells (1980) (30)
Separation of neutralizing and hemagglutination-inhibiting antibody activities and specificity of antisera to sodium dodecyl sulfate-derived polypeptides of polyoma virions (1980) (29)
Engagement of the CD4 receptor inhibits the interleukin‐2‐dependent proliferation of human T cells transformed by Herpesvirus saimiri (1994) (27)
Identification and characterization of a myristylated and palmitylated serine/threonine protein kinase. (1999) (25)
Signaling pathways controlling trophoblast cell differentiation: Src family protein tyrosine kinases in the rat. (1997) (25)
Reconstitution of the B Cell Antigen Receptor Signaling Components in COS Cells (*) (1995) (24)
Signal Transduction by Immunoglobulin Is Mediated Through Igc ~ and Ig ~ By (2003) (23)
Neuron‐specific splicing of C‐SRC cDNA RNA in human brain (1989) (22)
Analysis of middle tumor antigen and pp60c-src interactions in polyomavirus-transformed rat cells (1987) (22)
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in a rat mast cell line. Impairment of tyrosine kinase-dependent signal transduction and the subsequent degranulation response. (1993) (22)
Neuron-specific splicing of C-SRC RNA in human brain. (1989) (21)
Signal Transduction through the 1 Integrin Family Surface Adhesion Molecules VLA-4 and VLA-5 of Human B-cell Precursors Activates CD19 Receptor-associated Protein-tyrosine Kinases (*) (1996) (21)
Temporal activation of nontransmembrane protein-tyrosine kinases following mast cell Fc epsilon RI engagement. (1995) (19)
Synthesis and Application of Fmoc-O-[Bis(dimethylamino)phosphono]tyrosine, a Versatile Protected Phosphotyrosine Equivalent (1995) (18)
A determinant of polyomavirus virulence enhances virus growth in cells of renal origin (1985) (17)
Analysis of the tyrosine protein kinase p56lck expressed as a glutathione S-transferase fusion protein in Spodoptera frugiperda cells. (1993) (15)
The FcgammaRII receptor triggers pp125FAK phosphorylation in platelets. (1996) (15)
Polyomavirus transforms rat F111 and mouse NIH 3T3 cells by different mechanisms (1989) (14)
Analysis of polyomavirus middle-T-antigen-transformed rat cell variants expressing different levels of pp60c-src (1987) (13)
In vitro association and phosphorylation of polyoma virus middle T antigen by cellular tyrosyl kinase activity. (1984) (13)
The cytoplasmic domain of CD4 is required for stable association with the lymphocyte‐specific tyrosine protein kinase p56lck (1990) (12)
Analysis of pp60c-src protein kinase activity in hamster embryo cells transformed by simian virus 40, human adenoviruses, and bovine papillomavirus 1 (1986) (11)
Analysis of styryl-based inhibitors of the lymphocyte tyrosine protein kinase p56lck. (1991) (11)
Role of tyrosine phosphorylation in radiation-induced cell cycle-arrest of leukemic B-cell precursors at the G2-M transition checkpoint. (1996) (11)
Role of hydroxyl radicals in radiation-induced activation of lyn tyrosine kinase in human B-cell precursors. (1996) (11)
Coordinate alteration of pp60c-src abundance and c-src RNA expression in human neuroblastoma variants. (1989) (11)
Signal transduction through a biomolecular receptor tyrosine protein kinase composed of a platelet-derived growth factor receptor-CD4 chimera and the nonreceptor tyrosine protein kinase Lck. (1993) (11)
Immune‐Complex Assays for Tyrosine Protein Kinases (1993) (10)
Delayed hypersensitivity to Staphylococcus aureus in mice: in vitro responses to isolated Staphylococcal antigens. (1979) (10)
Stimulation of pp60c‐src tyrosyl kinase activity in polyoma virus–infected mouse cells is closely associated with polyoma middle tumor antigen synthesis (1985) (10)
Inhibition of polyoma virus middle T antigen-associated tyrosyl kinase activity by N-ethylmaleimide. (1983) (10)
src-related protein tyrosine kinases. (1989) (10)
Diminished tyrosine protein kinase activity in T cells unresponsive to TCR stimulation (1994) (10)
Structure and developmental regulation of the murine ctk gene. (1995) (9)
Palmitylation of Src family tyrosine kinases regulates functional interaction with a B cell substrate. (1997) (8)
CD4 and p56lck can stably associate when co-expressed in NIH3T3 cells. (1989) (8)
Comparison of tyrosine kinase activation by mitogenic and nonmitogenic anti-IgD antibodies. (1992) (8)
Detection and quantitation of Newcastle disease virus proteins in infected chicken embryo cells (1982) (7)
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p 561 ck ( interleukin 2 receptor / tyrosine phosphorylation ) (7)
Effect of butylated hydroxytoluene on Newcastle disease virus. (1980) (6)
Large-scale production of polyoma middle T antigen by using genetically engineered tumors (1985) (5)
Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase. (1993) (5)
Pillars article: the CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. 1994. (2010) (5)
Nonreceptor protein tyrosine kinase involvement in signal transduction and immunodeficiency disease. (1995) (5)
Induction and specificity of delayed hypersensitivity to Staphylococcus aureus in mice. (1978) (5)
Pillars Article: The CD4 and CD8 T Cell Surface Antigens are Associated with the Internal Membrane Tyrosine-Protein Kinase p56lck. Cell 1988. 55: 301–308 (2010) (4)
Synthesis and Application of Fmoc-O-(bis(dimethylamino)phosphono) tyrosine, a Versatile Protected Phosphotyrosine Equivalent. (2010) (4)
Polyomavirus Transforms Rat Fill and Mouse NIH 3 T 3 Cells by Different Mechanisms (4)
Serum stimulated DNA synthesis in mouse embryo fibroblasts. Synergistic enhancement by staphylococcal lipoteichoic acid. (1978) (3)
Delayed hypersensitivity to Staphylococcus aureus in mice: in vivo responses to isolated Staphylococcal antigens. (1979) (3)
Involvement of nonreceptor protein tyrosine kinases in multichain immune recognition receptor signal transduction. (1994) (2)
A subclass of polyomavirus middle tumor antigen binds to DNA cellulose (1986) (2)
Structural influences of styryl-based inhibitors on epidermal growth factor receptor and p56lck tyrosine-specific protein kinases. (1991) (2)
Developmentally regulated genes in neuroblastoma. (1988) (2)
Examination of the possible mediation of antineoplastic effects of opiates through the inhibition of tyrosine-specific protein kinases. (1991) (2)
Cancer Therapy : Preclinical Characterization of Alisertib ( MLN 8237 ) , an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays (2011) (2)
Potentiation of B‐Cell Antigen Receptor‐mediated Signal Transduction by the Heterologous src Family Protein Tyrosine Kinase, src (1995) (2)
Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cyl (2004) (1)
Delayed hypersensitivity to Staphylococcus aureus in mice: kinetics of induction. (1983) (1)
Dependent on Syk Kinase of Akt Promotes B Cell Survival and Is B Cell Antigen Receptor-Induced Activation (2000) (1)
Delayed hypersensitivity to Staphylococcus aureus in mice: characterization of a membrane immunogen involved in delayed hypersensitivity. (1981) (1)
Expression of exogenous p59fyn modulates signaling in an immature B cell line, WEHI-231. (1996) (1)
Cellular and biochemical characterization of an inhibitor of the Ubiquitin Activating Enzyme (UAE) (2011) (1)
Molecular mechanism of paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal (2001) (1)
A Subclass ofPolyomavirus Middle TumorAntigen Bindsto DNA Cellulose (1986) (0)
Demonstration of endocytosis during Newcastle disease virus infection of chicken embryo cell cultures. (1985) (0)
System for expressing Lck protein (1994) (0)
The viral protein p40Tip interacts with p56Lck inHerpesvirus saimiri transformed human T cells (2007) (0)
Erratum: Membrane-associated CD19-LYN complex is an endogenous p53- independent and Bcl-2-independent regulator of apoptosis in human B-lineage lymphoma cells (Proceedings of the National Academy of Sciences of the United States (October 10, 1995) 92 (9575-9579)) (1996) (0)
CELL MEDIATED IMMUNE RESPONSES TO STAPHYLOCOCCUS AUREUS IN MICE. (1977) (0)
Igao and lg,B Are Functionally Homologous to the Signaling Proteins of the T-Cell Receptor (0)
Activation of pp60O-src protein kinase activity in human colon carcinoma (2003) (0)
The Role of Non-receptor Protein Tyrosine Kinases in Receptor Mediated Cellular Activation and Immunodeficiency Disease (1996) (0)
Assessment of the Effects of Tyrosine Protein Kinase Inhibitors (1993) (0)
Sequences involved in binding of the viral protein p40Tip to the tyrosine kinase p56Lck (2007) (0)
Advances in Brief MMAC 1 / PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines ' (2006) (0)
Tumor Cell Lines Mutations in Primary Tumor Specimens and MMAC 1 / PTEN Updated (2006) (0)

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Joseph Beene Bolen's Published Works

Published Works

What Schools Are Affiliated With Joseph Beene Bolen?

Joseph Beene Bolen's AcademicInfluence.com Rankings