Joseph Beene Bolen
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(Suggest an Edit or Addition)Joseph Beene Bolen's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56 lck (1988) (1173)
- Syk tyrosine kinase required for mouse viability and B-cell development (1995) (664)
- Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck (1989) (609)
- Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases (1992) (479)
- Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase (2007) (407)
- Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. (1991) (398)
- Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases. (1991) (376)
- Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. (1995) (349)
- Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn. (1993) (306)
- Activation of pp60c-src protein kinase activity in human colon carcinoma. (1987) (287)
- Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation (1984) (276)
- Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases (1995) (274)
- Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays (2011) (259)
- Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. (1994) (258)
- Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells (1995) (236)
- A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen (1998) (226)
- Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3. (1994) (223)
- CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. (1993) (219)
- Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta (1993) (219)
- Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. (1994) (212)
- Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues. (1986) (211)
- Granulocyte macrophage‐colony stimulating factor stimulates both association and activation of phosphoinositide 3OH‐kinase and src‐related tyrosine kinase(s) in human myeloid derived cells. (1993) (199)
- Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. (1998) (198)
- The Src family of tyrosine protein kinases in hemopoietic signal transduction (1992) (190)
- Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells. (1994) (187)
- Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase. (1993) (183)
- Inability of CD8α′polypeptides to associate with p56 lck correlates with impaired function in vitro and lack of expression in vivo (1989) (178)
- T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. (1991) (178)
- Nonreceptor tyrosine protein kinases. (1993) (177)
- The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. (1997) (176)
- B Cell Antigen Receptor-Induced Activation of Akt Promotes B Cell Survival and Is Dependent on Syk Kinase1 (2000) (168)
- RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells (1996) (162)
- Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation (1988) (159)
- Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways (1989) (159)
- Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1 (1999) (158)
- Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase (1995) (156)
- Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen. (1984) (156)
- Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus (1991) (154)
- An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases (1992) (153)
- ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction. (1994) (151)
- Leukocyte protein tyrosine kinases: potential targets for drug discovery. (1997) (151)
- Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif (1994) (149)
- Endogenous Reactive Oxygen Intermediates Activate Tyrosine Kinases in Human Neutrophils (*) (1996) (146)
- The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. (1996) (139)
- The Product of the Herpesvirus saimiri Open Reading Frame 1 (Tip) Interacts with T Cell-specific Kinase p56lck in Transformed Cells (*) (1995) (129)
- Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI (1995) (129)
- Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking. (1992) (121)
- Exposure of B-lineage Lymphoid Cells to Low Energy Electromagnetic Fields Stimulates Lyn Kinase (*) (1995) (119)
- Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20 (1995) (118)
- Protein tyrosine kinases in the initiation of antigen receptor signaling. (1995) (118)
- Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny. (1993) (116)
- Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement. (1994) (113)
- Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family. (1994) (111)
- Regulatory factors that determine growth and phenotype of normal human melanocytes. (1988) (105)
- Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product. (1985) (105)
- HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. (1996) (103)
- Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes (1989) (97)
- Safety Evaluation of Lipid Nanoparticle–Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey (2018) (94)
- Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. (1987) (93)
- Transcriptional analysis of the PTEN/MMAC1 pseudogene, ΨPTEN (1999) (92)
- Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924. (2012) (92)
- The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2 (1996) (91)
- src-related tyrosine protein kinases as signaling components in hematopoietic cells. (1990) (91)
- Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells. (1987) (89)
- Identification of a novel neuronal C-SRC exon expressed in human brain (1990) (88)
- Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C. (1988) (87)
- TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck. (1996) (87)
- Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex. (1997) (86)
- Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1. (1992) (82)
- Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction. (1994) (82)
- Specific Association of Tyrosine-phosphorylated c-Cbl with Fyn Tyrosine Kinase in T Cells* (1996) (82)
- No T-cell tyrosine protein kinase signalling or calcium mobilization after CD4 association with HIV-1 or HIV-1 gp120 (1990) (79)
- Bicyclic compounds as ring-constrained inhibitors of protein-tyrosine kinase p56lck. (1993) (77)
- Reconstitution of Btk Signaling by the Atypical Tec Family Tyrosine Kinases Bmx and Txk* (1999) (76)
- Expression and interactions of the Src family of tyrosine protein kinases in T lymphocytes. (1991) (75)
- Association of Src-like protein tyrosine kinases with the CD2 cell surface molecule in rat T lymphocytes and natural killer cells (1992) (75)
- Cross-linking of Fc gamma receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel. (1994) (73)
- Tyrosine phosphorylation and association of Syk with Fc gamma RII in monocytic THP-1 cells. (1995) (71)
- Selective Activation of T Cell Kinase p56lck by Herpesvirus saimiri Protein Tip (*) (1996) (71)
- A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells (2001) (70)
- Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. (1996) (70)
- Differences in the subpopulations of the structural proteins of polyoma virions and capsids: biological functions of the multiple VP1 species (1981) (69)
- Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells (1989) (67)
- Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1 (1989) (66)
- MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors (2015) (66)
- Signal transduction by the SRC family of tyrosine protein kinases in hemopoietic cells. (1991) (63)
- Production and characterization of a monoclonal antibody that binds Reed-Sternberg cells. (1985) (63)
- The src family of tyrosine protein kinases in hemopoietic signal transduction (1992) (61)
- CD4, CD8 and the role of CD45 in T-cell activation. (1993) (58)
- Expression of p60fyn in human platelets. (1990) (57)
- Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45. (1994) (56)
- The FcγRII Receptor Triggers pp125FAK Phosphorylation in Platelets* (1996) (55)
- Tyrosine phosphorylation within the amino-terminal domain of pp60c-src molecules associated with polyoma virus middle-sized tumor antigen. (1985) (53)
- The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity (2000) (52)
- Effects of the tyrosine‐kinase inhibitor geldanamycin on ligand‐induced HER‐2/NEU activation, receptor expression and proliferation of HER‐2‐positive malignant cell lines (1997) (52)
- Differential adsorption of polyoma virions and capsids to mouse kidney cells and guinea pig erythrocytes (1979) (51)
- Ig alpha and Ig beta are functionally homologous to the signaling proteins of the T-cell receptor (1994) (49)
- Interleukin-2-induced tyrosine phosphorylation of Shc proteins correlates with factor-dependent T cell proliferation. (1994) (48)
- Identification of distinct populations of PI-3 kinase activity following T-cell activation. (1992) (47)
- Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells. (1995) (45)
- Regulation of pp60c-src synthesis by inducible RNA complementary to c-src mRNA in polyomavirus-transformed rat cells (1986) (44)
- Interaction of p72 syk with the gand bSubunits of the High-Affinity Receptor for Immunoglobulin E, FcεRI (1995) (42)
- Signal transduction by the cytoplasmic domains of Fc epsilon RI-gamma and TCR-zeta in rat basophilic leukemia cells. (1992) (41)
- Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. (1989) (41)
- Middle tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with pp60c-src (1985) (41)
- A function for the lck proto-oncogene. (1989) (40)
- Temporal Activation of Nontransmembrane Protein-tyrosine Kinases following Mast Cell FcεRI Engagement (*) (1995) (39)
- Phosphonate-containing inhibitors of tyrosine-specific protein kinases. (1991) (39)
- Analysis of pp60c‐src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells (1987) (37)
- The Raf-1 serine-threonine kinase is a substrate for the p56lck protein tyrosine kinase in human T-cells. (1991) (35)
- Syk Mutation in Jurkat E6-derived Clones Results in Lack of p72syk Expression (*) (1995) (35)
- Molecular Cloning of Rodent p72Syk. (1995) (35)
- Activation-dependent tyrosine phosphorylation of Fyn-associated proteins in T lymphocytes. (1994) (34)
- Physical and Functional Interactions between Lyn and p34 Kinases in Irradiated Human B-cell Precursors (*) (1996) (34)
- Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase (1999) (31)
- Cross-linking of surface immunoglobulin activates src-related tyrosine kinases in WEHI 231 cells. (1992) (30)
- Analysis of the c-src gene product structure, abundance, and protein kinase activity in human neuroblastoma and glioblastoma cells. (1987) (30)
- Isolation and characterization of polyoma uncoating intermediates from the nuclei of infected mouse cells (1980) (30)
- Separation of neutralizing and hemagglutination-inhibiting antibody activities and specificity of antisera to sodium dodecyl sulfate-derived polypeptides of polyoma virions (1980) (29)
- Engagement of the CD4 receptor inhibits the interleukin‐2‐dependent proliferation of human T cells transformed by Herpesvirus saimiri (1994) (27)
- Identification and characterization of a myristylated and palmitylated serine/threonine protein kinase. (1999) (25)
- Signaling pathways controlling trophoblast cell differentiation: Src family protein tyrosine kinases in the rat. (1997) (25)
- Reconstitution of the B Cell Antigen Receptor Signaling Components in COS Cells (*) (1995) (24)
- Signal Transduction by Immunoglobulin Is Mediated Through Igc ~ and Ig ~ By (2003) (23)
- Neuron‐specific splicing of C‐SRC cDNA RNA in human brain (1989) (22)
- Analysis of middle tumor antigen and pp60c-src interactions in polyomavirus-transformed rat cells (1987) (22)
- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in a rat mast cell line. Impairment of tyrosine kinase-dependent signal transduction and the subsequent degranulation response. (1993) (22)
- Neuron-specific splicing of C-SRC RNA in human brain. (1989) (21)
- Signal Transduction through the 1 Integrin Family Surface Adhesion Molecules VLA-4 and VLA-5 of Human B-cell Precursors Activates CD19 Receptor-associated Protein-tyrosine Kinases (*) (1996) (21)
- Temporal activation of nontransmembrane protein-tyrosine kinases following mast cell Fc epsilon RI engagement. (1995) (19)
- Synthesis and Application of Fmoc-O-[Bis(dimethylamino)phosphono]tyrosine, a Versatile Protected Phosphotyrosine Equivalent (1995) (18)
- A determinant of polyomavirus virulence enhances virus growth in cells of renal origin (1985) (17)
- Analysis of the tyrosine protein kinase p56lck expressed as a glutathione S-transferase fusion protein in Spodoptera frugiperda cells. (1993) (15)
- The FcgammaRII receptor triggers pp125FAK phosphorylation in platelets. (1996) (15)
- Polyomavirus transforms rat F111 and mouse NIH 3T3 cells by different mechanisms (1989) (14)
- Analysis of polyomavirus middle-T-antigen-transformed rat cell variants expressing different levels of pp60c-src (1987) (13)
- In vitro association and phosphorylation of polyoma virus middle T antigen by cellular tyrosyl kinase activity. (1984) (13)
- The cytoplasmic domain of CD4 is required for stable association with the lymphocyte‐specific tyrosine protein kinase p56lck (1990) (12)
- Analysis of pp60c-src protein kinase activity in hamster embryo cells transformed by simian virus 40, human adenoviruses, and bovine papillomavirus 1 (1986) (11)
- Analysis of styryl-based inhibitors of the lymphocyte tyrosine protein kinase p56lck. (1991) (11)
- Role of tyrosine phosphorylation in radiation-induced cell cycle-arrest of leukemic B-cell precursors at the G2-M transition checkpoint. (1996) (11)
- Role of hydroxyl radicals in radiation-induced activation of lyn tyrosine kinase in human B-cell precursors. (1996) (11)
- Coordinate alteration of pp60c-src abundance and c-src RNA expression in human neuroblastoma variants. (1989) (11)
- Signal transduction through a biomolecular receptor tyrosine protein kinase composed of a platelet-derived growth factor receptor-CD4 chimera and the nonreceptor tyrosine protein kinase Lck. (1993) (11)
- Immune‐Complex Assays for Tyrosine Protein Kinases (1993) (10)
- Delayed hypersensitivity to Staphylococcus aureus in mice: in vitro responses to isolated Staphylococcal antigens. (1979) (10)
- Stimulation of pp60c‐src tyrosyl kinase activity in polyoma virus–infected mouse cells is closely associated with polyoma middle tumor antigen synthesis (1985) (10)
- Inhibition of polyoma virus middle T antigen-associated tyrosyl kinase activity by N-ethylmaleimide. (1983) (10)
- src-related protein tyrosine kinases. (1989) (10)
- Diminished tyrosine protein kinase activity in T cells unresponsive to TCR stimulation (1994) (10)
- Structure and developmental regulation of the murine ctk gene. (1995) (9)
- Palmitylation of Src family tyrosine kinases regulates functional interaction with a B cell substrate. (1997) (8)
- CD4 and p56lck can stably associate when co-expressed in NIH3T3 cells. (1989) (8)
- Comparison of tyrosine kinase activation by mitogenic and nonmitogenic anti-IgD antibodies. (1992) (8)
- Detection and quantitation of Newcastle disease virus proteins in infected chicken embryo cells (1982) (7)
- T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p 561 ck ( interleukin 2 receptor / tyrosine phosphorylation ) (7)
- Effect of butylated hydroxytoluene on Newcastle disease virus. (1980) (6)
- Large-scale production of polyoma middle T antigen by using genetically engineered tumors (1985) (5)
- Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase. (1993) (5)
- Pillars article: the CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. 1994. (2010) (5)
- Nonreceptor protein tyrosine kinase involvement in signal transduction and immunodeficiency disease. (1995) (5)
- Induction and specificity of delayed hypersensitivity to Staphylococcus aureus in mice. (1978) (5)
- Pillars Article: The CD4 and CD8 T Cell Surface Antigens are Associated with the Internal Membrane Tyrosine-Protein Kinase p56lck. Cell 1988. 55: 301–308 (2010) (4)
- Synthesis and Application of Fmoc-O-(bis(dimethylamino)phosphono) tyrosine, a Versatile Protected Phosphotyrosine Equivalent. (2010) (4)
- Polyomavirus Transforms Rat Fill and Mouse NIH 3 T 3 Cells by Different Mechanisms (4)
- Serum stimulated DNA synthesis in mouse embryo fibroblasts. Synergistic enhancement by staphylococcal lipoteichoic acid. (1978) (3)
- Delayed hypersensitivity to Staphylococcus aureus in mice: in vivo responses to isolated Staphylococcal antigens. (1979) (3)
- Involvement of nonreceptor protein tyrosine kinases in multichain immune recognition receptor signal transduction. (1994) (2)
- A subclass of polyomavirus middle tumor antigen binds to DNA cellulose (1986) (2)
- Structural influences of styryl-based inhibitors on epidermal growth factor receptor and p56lck tyrosine-specific protein kinases. (1991) (2)
- Developmentally regulated genes in neuroblastoma. (1988) (2)
- Examination of the possible mediation of antineoplastic effects of opiates through the inhibition of tyrosine-specific protein kinases. (1991) (2)
- Cancer Therapy : Preclinical Characterization of Alisertib ( MLN 8237 ) , an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays (2011) (2)
- Potentiation of B‐Cell Antigen Receptor‐mediated Signal Transduction by the Heterologous src Family Protein Tyrosine Kinase, src (1995) (2)
- Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cyl (2004) (1)
- Delayed hypersensitivity to Staphylococcus aureus in mice: kinetics of induction. (1983) (1)
- Dependent on Syk Kinase of Akt Promotes B Cell Survival and Is B Cell Antigen Receptor-Induced Activation (2000) (1)
- Delayed hypersensitivity to Staphylococcus aureus in mice: characterization of a membrane immunogen involved in delayed hypersensitivity. (1981) (1)
- Expression of exogenous p59fyn modulates signaling in an immature B cell line, WEHI-231. (1996) (1)
- Cellular and biochemical characterization of an inhibitor of the Ubiquitin Activating Enzyme (UAE) (2011) (1)
- Molecular mechanism of paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal (2001) (1)
- A Subclass ofPolyomavirus Middle TumorAntigen Bindsto DNA Cellulose (1986) (0)
- Demonstration of endocytosis during Newcastle disease virus infection of chicken embryo cell cultures. (1985) (0)
- System for expressing Lck protein (1994) (0)
- The viral protein p40Tip interacts with p56Lck inHerpesvirus saimiri transformed human T cells (2007) (0)
- Erratum: Membrane-associated CD19-LYN complex is an endogenous p53- independent and Bcl-2-independent regulator of apoptosis in human B-lineage lymphoma cells (Proceedings of the National Academy of Sciences of the United States (October 10, 1995) 92 (9575-9579)) (1996) (0)
- CELL MEDIATED IMMUNE RESPONSES TO STAPHYLOCOCCUS AUREUS IN MICE. (1977) (0)
- Igao and lg,B Are Functionally Homologous to the Signaling Proteins of the T-Cell Receptor (0)
- Activation of pp60O-src protein kinase activity in human colon carcinoma (2003) (0)
- The Role of Non-receptor Protein Tyrosine Kinases in Receptor Mediated Cellular Activation and Immunodeficiency Disease (1996) (0)
- Assessment of the Effects of Tyrosine Protein Kinase Inhibitors (1993) (0)
- Sequences involved in binding of the viral protein p40Tip to the tyrosine kinase p56Lck (2007) (0)
- Advances in Brief MMAC 1 / PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines ' (2006) (0)
- Tumor Cell Lines Mutations in Primary Tumor Specimens and MMAC 1 / PTEN Updated (2006) (0)
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