Jonathan B. Rothbard
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Philosophy Biology
Jonathan B. Rothbard's Degrees
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Jonathan B. Rothbard's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides (1986) (1752)
- The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. (2000) (1447)
- Polyarginine enters cells more efficiently than other polycationic homopolymers. (2000) (980)
- Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy (1994) (660)
- A sequence pattern common to T cell epitopes. (1988) (605)
- Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation (2000) (588)
- A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. (1988) (554)
- Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. (2004) (538)
- T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis (1986) (470)
- Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2 (1987) (430)
- Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis (1993) (410)
- Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. (1988) (354)
- A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes (1989) (338)
- Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. (2002) (287)
- Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains. (1982) (285)
- Adaptive translocation: the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells. (2005) (276)
- Stress proteins may provide a link between the immune response to infection and autoimmunity. (1989) (268)
- Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. (1992) (262)
- Peptide binding to HLA‐DR1: a peptide with most residues substituted to alanine retains MHC binding. (1990) (245)
- Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands. (1995) (242)
- Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs (1992) (240)
- Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2 (2015) (223)
- Structure, expression and divergence of T-cell receptor β-chain variable regions (1984) (202)
- Interactions between Immunogenic Peptides and MHC Proteins (1991) (200)
- Expression of the c‐erbB‐2 protein in normal and transformed cells (1987) (199)
- Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide. (1997) (198)
- Immunogenicity of synthetic peptides from circumsporozoite protein of Plasmodium falciparum. (1985) (189)
- A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA. (1991) (182)
- Detection of T cells in paraffin wax embedded tissue using antibodies against a peptide sequence from the CD3 antigen. (1989) (180)
- Gonococcal pili. Primary structure and receptor binding domain (1984) (173)
- Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. (1998) (172)
- Structural model of HLA-DR1 restricted T cell antigen recognition (1988) (167)
- Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein. (1988) (166)
- Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis [published erratum appears in J Exp Med 1988 Jul 1;168(1):455] (1988) (165)
- Use of synthetic peptides of influenza nucleoprotein to define epitopes recognized by class I-restricted cytotoxic T lymphocytes (1987) (158)
- Oligocarbamate molecular transporters: design, synthesis, and biological evaluation of a new class of transporters for drug delivery. (2002) (149)
- Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. (1996) (148)
- Cloning and sequencing of a Moraxella bovis pilin gene (1985) (146)
- Mapping of T cell epitopes using recombinant antigens and synthetic peptides. (1987) (141)
- Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. (2006) (138)
- Molecular Transporters: Synthesis of Oligoguanidinium Transporters and Their Application to Drug Delivery and Real‐Time Imaging (2006) (137)
- Molecular basis for cytolytic T-lymphocyte recognition of the murine cytomegalovirus immediate-early protein pp89 (1988) (136)
- Exploration of requirements for peptide binding to HLA DRB1*0101 and DRB1*0401. (1994) (136)
- Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein (1988) (133)
- HLA-A2 peptides can regulate cytolysis by human allogeneic T lymphocytes (1987) (133)
- Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins. (1989) (131)
- Interactions between immunogenic peptides and MHC proteins. (1991) (130)
- Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces. (1990) (127)
- In vitro proliferative responses and antibody titers specific to human acetylcholine receptor synthetic peptides in patients with myasthenia gravis and relation to HLA class II genes. (1988) (126)
- Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site (1988) (126)
- Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation (2011) (125)
- Specificity of an HLA‐DRB1*0401‐restricted T cell response to type II collagen (1996) (124)
- Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits. (1987) (121)
- Effect of natural polymorphism at residue 86 of the HLA-DR beta chain on peptide binding. (1991) (107)
- Antibodies to peptides corresponding to a conserved sequence of gonococcal pilins block bacterial adhesion. (1985) (106)
- Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27. (1990) (104)
- Prediction of peptide affinity to HLA DRB1*0401. (1994) (101)
- Strain-specific and common epitopes of gonococcal pili (1984) (100)
- Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia (1987) (96)
- Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells (1988) (94)
- HLA B37 determines an influenza A virus nucleoprotein epitope recognized by cytotoxic T lymphocytes (1986) (93)
- Human T cell responses to human papillomavirus type 16 L1 and E6 synthetic peptides: identification of T cell determinants, HLA-DR restriction and virus type specificity. (1990) (90)
- A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo. (1988) (88)
- Role of the polymorphic residues in HLA-DR molecules in allele-specific binding of peptide ligands. (1994) (86)
- Characterization of epitopes recognized by hapten-specific CD4+ T cells. (1995) (83)
- A juxta-membrane epitope on the human acetylcholine receptor recognized by T cells in myasthenia gravis. (1988) (82)
- Therapeutic Effects of Systemic Administration of Chaperone αB-Crystallin Associated with Binding Proinflammatory Plasma Proteins* (2012) (78)
- Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice (2007) (77)
- Guanidinium rich peptide transporters and drug delivery. (2003) (75)
- T-cell reactivity in myasthenia gravis. (1989) (72)
- Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates. (2003) (71)
- Delivery of antimicrobials into parasites (2003) (68)
- Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. (1993) (67)
- Structural analysis of a peptide--HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor. (1989) (66)
- Amyloid Fibrils Composed of Hexameric Peptides Attenuate Neuroinflammation (2013) (62)
- Peptides and the cellular immune response (1986) (59)
- Conformational and structural characteristics of peptides binding to HLA-DR molecules. (1991) (59)
- Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake. (2005) (58)
- Quantitative analysis of T cell activation: role of TCR/ligand density and TCR affinity. (1996) (58)
- Peptide-mediated modulation of T-cell allorecognition. (1988) (58)
- αB-crystallin improves murine cardiac function and attenuates apoptosis in human endothelial cells exposed to ischemia-reperfusion. (2011) (57)
- Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis* (2012) (57)
- T cell specificity for class II (I-A) and the encephalitogenic N-terminal epitope of the autoantigen myelin basic protein. (1987) (54)
- Pili of Neisseria meningitidis. Analysis of structure and investigation of structural and antigenic relationships to gonococcal pili (1985) (49)
- Synthetic peptides as vaccines (1987) (48)
- Comparison between two peptide epitopes presented to cytotoxic T lymphocytes by HLA-A2. Evidence for discrete locations within HLA-A2. (1989) (47)
- Localisation of islet amyloid peptide in lipofuscin bodies and secretory granules of human B-cells and in islets of type-2 diabetic subjects (1989) (46)
- L-arginine polymers inhibit the development of vein graft neointimal hyperplasia. (2001) (46)
- Photoreactions of charged benzophenone with amphiphiles in micelles and multicomponent aggregates as conformational probes (1978) (44)
- Prediction and identification of an HLA‐DR‐restricted T cell determinant in the 19‐kDa protein of Mycobacteriurn tuberculosis (1988) (43)
- Detection of peptide-MHC class II complexes on the surface of intact cells. (1990) (42)
- An HIV-1 and HIV-2 cross-reactive cytotoxic T-cell epitope. (1990) (40)
- The mycobacterial GroEL stress protein: a common target of T-cell recognition in infection and autoimmunity. (1989) (40)
- Amino acid residues 56 to 69 of HLA-A2 specify an antigenic determinant shared by HLA-A2 and HLA-B17. (1986) (39)
- All eight unassigned reading frames of mouse mitochondrial DNA are expressed. (1984) (38)
- REMOTE FUNCTIONALIZATION REACTIONS AS CONFORMATIONAL PROBES FOR FLEXIBLE ALKYL CHAINS (1978) (38)
- Antibodies to synthetic peptides defined by cDNA cloning reveal a network of peptidergic neurons in Aplysia (1984) (36)
- The human T3 gamma chain is phosphorylated at serine 126 in response to T lymphocyte activation. (1987) (36)
- Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines. (1988) (36)
- Reversal of HLA restriction by a point mutation in an antigenic peptide. (1989) (35)
- Chaperone Activity of α B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis (2011) (34)
- Positioning of a peptide in the cleft of HLA-A2 by complementing amino acid changes. (1991) (34)
- Structure, expression and divergence of T-cell receptor beta-chain variable regions. (1984) (33)
- The autoimmune response of different mouse strains to T-cell epitopes of the human acetylcholine receptor alpha subunit. (1990) (33)
- Structure of the heavy chain of the H-2Kk histocompatibility antigen. (1980) (32)
- Apparent lack of MHC restriction in binding of class I HLA molecules to solid-phase peptides (1990) (32)
- An in vitro model of peptide-mediated immunomodulation of the human T cell response to Dermatophagoides spp (house dust mite). (1991) (31)
- Peptides recognized by class I restricted T cells also bind to MHC class II molecules. (1990) (31)
- Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide. (1994) (26)
- Syngeneic antiidiotypic immune responses to a B cell lymphoma. Comparison between heavy chain hypervariable region peptides and intact Ig as immunogens (1985) (26)
- DIABETES-ASSOCIATED PEPTIDE (1987) (26)
- T-cell recognition of influenza viral antigens. (1987) (26)
- Antigenic analysis of gonococcal pili using monoclonal antibodies (1984) (22)
- Rapid and Efficient Vascular Transport of Arginine Polymers Inhibits Myointimal Hyperplasia (2000) (21)
- Recognition of influenza virus proteins by cytotoxic T lymphocytes. (1989) (20)
- Definition of murine T helper cell determinants in the major capsid protein of human papillomavirus type 16. (1990) (19)
- Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells (2004) (19)
- Identification of mycobacterial antigens recognized by T lymphocytes. (1989) (18)
- Species conservation of the T cell lymphocyte CD2 cell surface antigen (1988) (16)
- Inhibition of T cell proliferation specific for acetylcholine receptor epitopes related to myasthenia gravis with antibody to T cell receptor or with competitive synthetic polymers. (1990) (16)
- Recruitment of alloreactive cytotoxic T lymphocytes by an antigenic peptide (1989) (16)
- CRYAB modulates the activation of CD4+ T cells from relapsing–remitting multiple sclerosis patients (2013) (14)
- Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease (2014) (12)
- Dephosphorylation of the human T lymphocyte CD3 antigen. (1989) (12)
- PREDOMINANT EXPRESSION OF A T CELL RECEPTOR V,6 GENE SUBFAMILY IN AUTOIMMUNE ENCEPHALOMYELITIS (2003) (12)
- Janus Faces of Amyloid Proteins in Neuroinflammation (2014) (12)
- Synthetic peptides as vaccines. (1987) (12)
- Pattern recognition among T-cell epitopes. (1987) (11)
- Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis. (2002) (11)
- L-arginine polymer mediated inhibition of graft coronary artery disease after cardiac transplantation. (2001) (10)
- The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. 1986. (2006) (10)
- L-Arginine polymers enhance coronary flow and reduce oxidative stress following cardiac transplantation in rats. (2003) (9)
- Major histocompatibility complex-peptide interactions. (1989) (9)
- Piet Mondrian’s trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011 (2013) (9)
- Comparison of three different forms of HLA‐DR4Dw4 proteins (1993) (8)
- Antigen Presentation: One size fits all (1994) (8)
- Differential stability of HLA-DR alleles independent of endogenous peptides. (1995) (7)
- Self-Assembling Peptides Form Immune Suppressive Amyloid Fibrils Effective in Autoimmune Encephalomyelitis. (2015) (6)
- Experimental strategies to explore the molecular details of MHC-peptide complexes. (1990) (5)
- The primary sequence and antigenic structure of gonococcal pilin: approaches towards a gonococcal vaccine. (1985) (5)
- Recognition of the HLA class II-peptide complex by T-cell receptor: reversal of major histocompatibility complex restriction of a T-cell clone by a point mutation in the peptide determinant. (1989) (5)
- Genetic background modulates outcome of therapeutic amyloid peptides in treatment of neuroinflammation (2016) (4)
- Blood and thymic lymphocyte responses to peptide sequences of the acetylcholine receptor in myasthenia gravis (1987) (4)
- An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis (2018) (3)
- Interactions between immunogenic peptides and HLA-DR molecules (1990) (3)
- STRAIN-SPECIFIC AND COMMON EPITOPES OF (1984) (3)
- Structural analysis of a peptide-HLA class II complex. (1989) (3)
- Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates. (2011) (2)
- Molecular understanding of cellular uptake by arginine-rich cell penetrating peptides (2006) (2)
- High Degeneracy of HLA DR-Peptide Interactions: Possible Ramifications for Vaccine Design (1989) (2)
- The Molecular Organization of Gonococcal Pili (1985) (2)
- Prediction of peptide affinity to HLA DR molecules. (1995) (2)
- Monoclonal antipeptide antibodies against amino acid residues 1101-1106 of human C4 distinguish C4A from C4B. (1991) (2)
- Prediction of peptide affinity to HLA DRB1*0401. (1995) (1)
- The ternary complex: T cell receptor, MHC protein, and immunogenic peptide. (1990) (1)
- Do amyloid fibrils induce inflammation, or does inflammation generate amyloid fibrils? (2022) (1)
- Mechanistic Insights into Guanidinium-Rich Transporters Entering Cells (2006) (1)
- Prediction and identification of bacterial and parasitic T-cell antigens and determinants. (1990) (1)
- Response to Comment on “Chaperone Activity of α B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis” (2011) (1)
- ARGININE POLYMERS INHIBIT GRAFT CORONARY ARTERY DISEASE FOLLOWING CARDIAC TRANSPLANTATION.: Abstract# 726 (2000) (0)
- Amyloid Fibril-Forming Hexapeptides Modulate The Immune Response And Reduce Symptoms In An Animal Model Of Multiple Sclerosis (S14.002) (2014) (0)
- Alleight unassigned reading frames ofmouse mitochondrial DNA areexpressed (1984) (0)
- Peptides Derived From HLA-A2 Modulate Lysis by HLA-A2-Specific Cytotoxic T Lymphocytes (1989) (0)
- Myelin peptide moieties and the use of forms related to autoimmune diseases methods (1996) (0)
- Variant and Mutant HLA-A2 Molecules Affect Recognition of Influenza Matrix Peptide 56–68 by Cytotoxic T Lymphocytes (1989) (0)
- Compositions et methodes de traitement de maladies (2005) (0)
- Table of Contents (1991) (0)
- Recognition of Viral Antigens by Cytotoxic T Lymphocytes (1989) (0)
- PILl OF NEISSER (2003) (0)
- Rules for the Presentation of Peptides by Class II Molecules of the Major Histocompatibility Complex (1993) (0)
- Correction (1988) (0)
- Compositions for multiple sclerosis and its treatment (1997) (0)
- 1023: EXPLORING THE ANTI-INFLAMMATORY EFFECTS OF THE AMYLOIDOGENIC HEXAPEPTIDE, AMYLIN28-33, IN SEPSIS (2015) (0)
- Enhanced binding of peptide to HLA-DR1 by point substitution (1992) (0)
- Apicomplexan pathways, inhibitors, and drug delivery (2005) (0)
- Janus Faces of Amyloid Proteins in Neuroinflammation (2014) (0)
- Studies of MHC Class II Restricted Antigen Recognition by Human T Cell Clones Using Transfectant Antigen-Presenting Cells (APC) (1989) (0)
- Peptide-mediated modulation of T-cell allorecognition ( antigen presentation / HLA class I major histocompatibility complex / influenza hemagglutinin ) (0)
- Structure of the heavy chain of the H-2 Kk histocompatibility antigen ( CNBr fragments / radiochemical sequence analyses / tunicamycin / phosphorylation ) (0)
- 1784 MONOCLONAL ANTIBODIES TO GONOCOCCAL PILl TABLE I Amino Acid Sequences of the Synthetic Oligopeptides and their Corresponding Location in MS 11 Pilin (2003) (0)
- Purification of Complexes between Peptide Antigens and Class II Major Histocompatibility Complex Antigens Using Biotinylated Peptides (1989) (0)
- Positioning of a peptide in the cleft of HLA-A 2 by complementing amino acid changes FRANCE (0)
- Table of Contents (1987) (0)
- Microsoft Word-JBC resubmittal Dec 28.docx (2011) (0)
- Cell recognition of a HLA-DR1-peptide complex: Analysis of an influenza hemagglutinin peptide in the antigen combining site (1990) (0)
- Antibodies to peptides correspondi gonococcal pilins block bacterial ad (immunogenicity/synthetic peptides/reverse turns/gonococcal vaccini (2016) (0)
- T.130. Small Heat Shock Proteins as Novel Therapeutic Treatments for Autoimmune Diseases (2009) (0)
- Immune Responses of Patients with Myasthenia Gravis to Peptides Representing Different Regions of the Human Acetylcholine Receptor (1989) (0)
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