Jay c. Unkeless
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Jay c. Unkelessbiology Degrees
Biology
#10980
World Rank
#14346
Historical Rank
Immunology
#698
World Rank
#720
Historical Rank

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Biology
Jay c. Unkeless's Degrees
- PhD Immunology University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Jay c. Unkeless's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors (1979) (1327)
- γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins (1985) (940)
- AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES (1973) (780)
- SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES (1974) (699)
- Toll-like receptors on tumor cells facilitate evasion of immune surveillance. (2005) (525)
- Human neutrophil Fc gamma receptor distribution and structure. (1982) (514)
- TLR signaling by tumor and immune cells: a double-edged sword (2008) (361)
- Treatment of refractory immune thrombocytopenic purpura with an anti-Fcγ-receptor antibody (1986) (341)
- Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator. (1974) (334)
- Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors. (1986) (332)
- Structure and function of human and murine receptors for IgG. (1988) (324)
- SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. (2008) (301)
- Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages (1975) (283)
- AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES (1973) (276)
- Function and heterogeneity of human Fc receptors for immunoglobulin G. (1989) (249)
- Structural Aspects and Heterogeneity of Immunoglobulin Fc Receptors. (1981) (248)
- Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells (2008) (232)
- Effects of immobilized immune complexes on Fc- and complement-receptor function in resident and thioglycollate-elicited mouse peritoneal macrophages (1979) (217)
- The presence of two Fc receptors on mouse macrophages: evidence from a variant cell line and differential trypsin sensitivity (1977) (209)
- Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. (2008) (189)
- Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis (1983) (188)
- Human neutrophil Fc , , receptor distribution and structure (188)
- Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. (2007) (187)
- Partial purification of a lipoprotein with 5'-nucleotidase activity from membranes of rat liver cells. (1968) (181)
- Inhibitory receptors, ITIM sequences and phosphatases. (1997) (168)
- Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody (1980) (159)
- Regulation of phagocytosis and [Ca2+]i flux by distinct regions of an Fc receptor. (1991) (152)
- Monoclonal anti-Fc receptor IgG blocks antibody enhancement of viral replication in macrophages (1981) (150)
- IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFN-γ Signaling Pathways* (2006) (145)
- AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19* (2009) (139)
- Characterization of a membrane pore-forming protein from Entamoeba histolytica (1982) (131)
- Cloning and characterization of a mouse cysteine proteinase. (1986) (122)
- Selective iodination and polypeptide composition of pinocytic vesicles (1980) (118)
- A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms. (1989) (114)
- Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma-receptor antibody. (1986) (102)
- Function of human Fc ?RIIA and Fc ?RIIIB (1995) (98)
- Epstein‐Barr virus‐induced gene 3 negatively regulates IL‐17, IL‐22 and RORγt (2008) (94)
- Convergence of Fcγ Receptor IIA and Fcγ Receptor IIIB Signaling Pathways in Human Neutrophils1 (2000) (93)
- Role for mouse macrophage IgG Fc receptor as ligand-dependent ion channel (1983) (89)
- Ontogeny of Fc receptors and complement receptor (CR3) during human myeloid differentiation. (1984) (87)
- Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN-γ-induced iNOS Gene Expression* (2003) (76)
- Macrophage membrane potential changes associated with gamma 2b/gamma 1 Fc receptor-ligand binding. (1983) (73)
- The inhibition of citrate synthase by adenosine triphosphate. (1968) (67)
- Notch-1 signaling regulates intestinal epithelial barrier function, through interaction with CD4+ T cells, in mice and humans. (2011) (67)
- In vivo handling of soluble complement fixing Ab/dsDNA immune complexes in chimpanzees. (1989) (67)
- Fc receptor modulation in mononuclear phagocytes maintained on immobilized immune complexes occurs by diffusion of the receptor molecule (1983) (63)
- Identification of soluble Fc receptors in mouse serum and the conditioned medium of stimulated B cells (1984) (61)
- Correlations among tyrosine phosphorylation of Shc, p72syk, PLC-gamma 1, and [Ca2+]i flux in Fc gamma RIIA signaling. (1994) (58)
- Stoichiometry and thermodynamics of the interaction between the Fc fragment of human IgG1 and its low-affinity receptor Fc gamma RIII. (1995) (57)
- Insertion and turnover of macrophage plasma membrane proteins. (1979) (57)
- The Ca2+ Dependence of Human Fcγ Receptor-initiated Phagocytosis (*) (1995) (56)
- Autoantibodies directed against different classes of Fc gamma R are found in sera of autoimmune patients. (1993) (55)
- Fc-receptor variants of a mouse macrophage cell line. (1979) (52)
- Mouse macrophage Fc receptor for IgG gamma 2b/gamma 1 in artificial and plasma membrane vesicles functions as a ligand-dependent ionophore. (1983) (52)
- Ubiquitin-dependent Degradation of Interferon Regulatory Factor-8 Mediated by Cbl Down-regulates Interleukin-12 Expression* (2005) (51)
- Soluble circulating Fc gamma receptors in human serum. A new ELISA assay for specific and quantitative detection. (1987) (47)
- IgM anti-Fc gamma R autoantibodies trigger neutrophil degranulation (1991) (46)
- Function of human Fc gamma RIIA and Fc gamma RIIIB. (1995) (45)
- Modulation of Fc receptors of mononuclear phagocytes by immobilized antigen-antibody complexes. Quantitative analysis of the relationship between ligand number and Fc receptor response (1983) (41)
- Convergence of Fc gamma receptor IIA and Fc gamma receptor IIIB signaling pathways in human neutrophils. (2000) (39)
- Change in expression of Fc gamma RIII (CD16) on neutrophils from human immunodeficiency virus-infected individuals. (1990) (39)
- Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine. (2009) (37)
- Autoimmune mice make anti-Fc gamma receptor antibodies (1990) (37)
- Specificity and class distribution of Fc gamma R-specific autoantibodies in patients with autoimmune disease. (1994) (36)
- Structure and modulation of Fc and complement receptors. (1984) (36)
- A specific Fc gamma receptor on cultured rat mesangial cells. (1989) (36)
- CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism1 (2009) (29)
- Analysis of macrophage differentiation and function with monoclonal antibodies. (1984) (28)
- Lateral mobility of lipid analogues and GPI-anchored proteins in supported bilayers determined by fluorescent bead tracking (1993) (27)
- Expression and characterization of a truncated murine Fc gamma receptor (1988) (27)
- Lateral mobility of FcγRIIa is reduced by protein kinase C activation (1995) (25)
- Interaction of TRAF6 with MAST205 Regulates NF-κB Activation and MAST205 Stability* (2004) (25)
- Fc receptor-mediated signal transduction (2005) (19)
- Cell surface expression of murine, rat, and human Fc receptors by Xenopus oocytes (1984) (19)
- Quantitation of proteins and internal antigen pools by a monoclonal sandwich radioimmune assay. (1983) (18)
- Microtubule-Associated Serine/Threonine Kinase-205 kDa and Fcγ Receptor Control IL-12 p40 Synthesis and NF-κB Activation12 (2004) (17)
- The Ca2+ dependence of human Fc gamma receptor-initiated phagocytosis. (1995) (17)
- An FcγRIII (CD16)-specific autoantibody from a patient with progressive systemic sclerosis (1993) (17)
- THE MACROPHAGE AS SECRETORY CELL1 (1975) (15)
- The diastereomers of -fluoroglutamate: complementary structural analogues. (1971) (14)
- Properties of a second epitope of the murine Fc receptor for aggregated IgG. (1987) (13)
- Circulating Fcγ receptor-specific autoantibodies in localized and systemic scleroderma (1995) (13)
- Functional ion channel formation by mouse macrophage IgG Fc receptor triggered by specific ligands (1985) (13)
- Molecular and functional studies of recombinant soluble Fcγ receptors (1990) (13)
- Studies on externally disposed plasma membrane proteins. Trinitrobenzene sulfonic acid derivatization and immune precipitation. (1981) (12)
- Oncogenic viruses. II. Mammalian fibroblast cultures transformed by dna and rna tumor viruses. (1973) (11)
- Serum cytokine and anti-FcγR autoantibody measurements in patients with systemic sclerosis (1996) (10)
- Serum cytokine and anti-Fc gamma R autoantibody measurements in patients with systemic sclerosis. (1996) (9)
- Innate immunity editorial overview (1991) (9)
- Fluorinated gamma-aminobutyric acid. Enzymatic synthesis and biological activity of a potentially useful analogue. (1970) (9)
- Fc Receptors on Mouse Macrophages (1980) (8)
- Modulation of Macrophage Plasma Membrane Receptors for IgG and Complement (1980) (8)
- Convergence of Fcg Receptor IIA and Fcg Receptor IIIB Signaling Pathways in Human Neutrophils (1999) (8)
- Expression of murine Fc receptors for IgG. (1990) (8)
- Circulating Fc gamma receptor-specific autoantibodies in localized and systemic scleroderma. (1995) (8)
- Soluble FcR block suppressor T cell activity at low concentration in vitro allowing isotype-specific antibody production. (1996) (8)
- IgM Anti-FcyR Autoantibodies Trigger Neutrophil Degranulation (2003) (7)
- Thermodynamic and Kinetic Aspects of the Reaction of γ-Fluoroglutamate with d-Glutamate Cyclase (1971) (7)
- Human Fc receptors for IgG. (1989) (6)
- Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation. (2004) (5)
- Lateral mobility of Fc gamma RIIa is reduced by protein kinase C activation. (1995) (4)
- Fcγ Receptors: A Diverse and Multifunctional Gene Family (1990) (4)
- Mouse macrophage Fc receptors. (1980) (3)
- Erratum: Toll-like receptors on tumor cells facilitate evasion of immune surveillance (Cancer Research (June 15, 2005) 65 (5009-5014)) (2005) (3)
- Editorial overview Fatal attraction: recognition and killing mechanisms in innate immunity (1993) (3)
- Expression of Foreign Proteins on the Surface of Xenopus laevis Oocytes (1985) (3)
- Human FC, receptors (2016) (2)
- Human Fc gamma receptors. (1989) (2)
- An Fc gamma RIII (CD16)-specific autoantibody from a patient with progressive systemic sclerosis. (1993) (2)
- Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance. (2019) (2)
- Mouse macrophage Fc receptor for IgGy2b/yl in artificial and plasma membrane vesicles functions as a ligand-dependent ionophore (signal ion/cation selectivity/proteoliposome/reconstitution) (1)
- Molecular and functional studies of recombinant soluble Fc gamma receptors. (1990) (1)
- Heterogeneity of human and murine Fc gamma receptors. (1986) (1)
- CCR 7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism 1 (2009) (1)
- Thermodynamic and kinetic aspects of the reaction of gamma-fluoroglutamate with D-glutamate cyclase. (1971) (1)
- S1783 Transferred CD4+ T Cells Induce Tight Junction Assembly Through Notch Signaling Pathway in the Distal Colon of RAG1-/- Deficient Mice (2010) (0)
- Thyroiditis and Primary Hypothyroidism CCR7 Deficiency in NOD Mice Leads to (2009) (0)
- Contents Volume 6 (2000) (0)
- SECRETION OF PLASMINOGEN A CTIVATOR BY STIMULATED MACROPHAGES (1974) (0)
- Method for determination of serum soluble receptors fc gamma, assay kit and corresponding applications (1987) (0)
- Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling. (2019) (0)
- Neutrophils Receptor IIIB Signaling Pathways in Human γ Receptor IIA and Fc γ Convergence of Fc (1999) (0)
- Nomenclature of the Fc receptors (1998) (0)
- Epstein-Barr virus-induced gene 3 is a negative regulator of IL-17 and protective immunity against Listeria monocytogenes (95.4) (2007) (0)
- Immune Complexes in Chimpanzees (1989) (0)
- Soluble and membrane bound murine immunoglobulin Fc receptor (1985) (0)
- Epstein-Barr virus-induced gene 3 is a negative regulator of IL-17 and protective immunity against Listeria monocytogenes (2007) (0)
- II. MAMMALL~N FIBROBLAST CULTURES TRANSFORMED BY DNA AXD RNA TI;~IOR VIRUSES (1973) (0)
- Transferred CD4+ T cells induce tight junction assembly through Notch signaling pathway in the distal colon of RAG1−/− deficient mice. (2011) (0)
- Heterogeneity of Murine and Human Fcγ Receptors (1987) (0)
- Contents to volume 6 (1983) (0)
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