John D. Brunzell

Q: What Schools Are Affiliated With John D. Brunzell

John D. Brunzell is affiliated with the following schools: University of Ottawa, University of British Columbia, University of Washington

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John D. Brunzell

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#63

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John D. Brunzell's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. (2002) (1071)
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. (2004) (985)
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. (2007) (926)
Lipoprotein Management in Patients With Cardiometabolic Risk (2008) (796)
Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. (2012) (662)
Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation. (2008) (554)
Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests. (1976) (511)
Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. (2004) (468)
Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man. (1973) (467)
Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. Diabetes Control and Complications Trial. (1998) (448)
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. (2004) (439)
Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects (2000) (413)
[8] Single vertical spin density gradient ultracentrifugation (1986) (401)
Nutrition principles and recommendations in diabetes. (2004) (377)
Sweet tooth reconsidered: Taste responsiveness in human obesity (1985) (376)
Triglyceride, high density lipoprotein, and coronary heart disease. (1993) (335)
Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. (2003) (324)
Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia. (1983) (317)
Reduced Plasma Peroxyl Radical Trapping Capacity and Increased Susceptibility of LDL to Oxidation In Poorly Controlled IDDM (1994) (314)
Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort. (2011) (311)
Myocardial infarction in the familial forms of hypertriglyceridemia. (1976) (307)
Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basal- and diet-induced activity. (1975) (305)
Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia. (2015) (293)
The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. (2003) (290)
25-Hydroxyvitamin D levels and albuminuria in the Third National Health and Nutrition Examination Survey (NHANES III). (2007) (289)
Apoproteins B and A-I and coronary artery disease in humans. (1984) (288)
Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia (1980) (279)
Evidence for a new pathophysiological mechanism for coronary artery disease regression: hepatic lipase-mediated changes in LDL density. (1999) (275)
Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Cardiovascular Complications of Type 1 Diabetes Mellitus. (2005) (271)
Inheritance of low density lipoprotein subclass patterns in familial combined hyperlipidemia. (1990) (270)
Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species* (2004) (269)
Detection and Characterization of the Heterozygote State for Lipoprotein Lipase Deficiency (1989) (261)
Effect of hepatic lipase on LDL in normal men and those with coronary artery disease. (1993) (260)
Obesity, body fat distribution, insulin sensitivity and Islet beta-cell function as explanations for metabolic diversity. (2001) (254)
Effects of rosiglitazone alone and in combination with atorvastatin on the metabolic abnormalities in type 2 diabetes mellitus. (2002) (253)
Cardiovascular disease mortality in familial forms of hypertriglyceridemia: A 20-year prospective study. (2000) (250)
Improved glucose tolerance with high carbohydrate feeding in mild diabetes. (1971) (241)
Adipokines, inflammation, and visceral adiposity across the menopausal transition: a prospective study. (2009) (241)
Nutrition Principles for the Management off Diabetes and Related Complications (1994) (239)
Clinical practice. Hypertriglyceridemia. (2007) (229)
Familial combined hyperlipidemia workshop (1989) (214)
Effect of estrogen on post-heparin lipolytic activity. Selective decline in hepatic triglyceride lipase. (1977) (208)
Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol. (1998) (204)
Gastric Inhibitory Polypeptide Enhanced Lipoprotein Lipase Activity in Cultured Preadipocytes (1979) (200)
Single vertical spin density gradient ultracentrifugation. (1986) (193)
The Effect of Excess Weight Gain With Intensive Diabetes Mellitus Treatment on Cardiovascular Disease Risk Factors and Atherosclerosis in Type 1 Diabetes Mellitus: Results From the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC) Stu (2013) (186)
Characterization of low‐density lipoprotein subclasses: methodologie approaches and clinical relevance (1994) (186)
Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet. (2003) (175)
Analysis of techniques to obtain plasma for measurement of levels of free fatty acids. (1993) (167)
American Diabetes Association position statement: evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. (2002) (164)
Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men. (2000) (163)
Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo. (1998) (161)
Dyslipidemia in the metabolic syndrome and type 2 diabetes mellitus. (2003) (158)
Lipoprotein lipase secretion by human monocyte-derived macrophages. (1982) (154)
Dyslipidemia of central obesity and insulin resistance. (1999) (154)
Familial combined hyperlipidemia and abnormal lipoprotein lipase. (1992) (150)
Central obesity, incident microalbuminuria, and change in creatinine clearance in the epidemiology of diabetes interventions and complications study. (2007) (149)
Increase of adipose tissue lipoprotein lipase activity with weight loss. (1981) (149)
Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia. (1997) (148)
Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich lipoproteins. (1993) (147)
Large Buoyant LDL‐like Particles in Hepatic Lipase Deficiency (1989) (142)
Chylomicronemia syndrome. Interaction of genetic and acquired hypertriglyceridemia. (1982) (140)
Cardiovascular complications in renal failure. (1991) (138)
Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects. (1988) (132)
Combined Statin and Niacin Therapy Remodels the High-Density Lipoprotein Proteome (2008) (129)
Human lipoprotein lipase: relationship of activity, heparin affinity, and conformation as studied with monoclonal antibodies. (1992) (122)
Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines. (1988) (121)
Human adipose tissue lipoprotein lipase: changes with feeding and relation to postheparin plasma enzyme. (1985) (121)
High frequency of mutations in the human lipoprotein lipase gene in pregnancy-induced chylomicronemia: possible association with apolipoprotein E2 isoform. (1994) (121)
Common Hepatic Lipase Gene Promoter Variant Determines Clinical Response to Intensive Lipid-Lowering Treatment (2000) (118)
The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity. (2001) (116)
Insulin therapy, hyperglycemia, and hypertension in type 1 diabetes mellitus. (2008) (115)
Impact of Excessive Weight Gain on Cardiovascular Outcomes in Type 1 Diabetes: Results From the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study (2017) (113)
The Correlation of Arteriosclerosis Obliterans with Lipoproteins in Insulin-Dependent and Non-Insulin-Dependent Diabetes (1979) (112)
Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia. (1993) (111)
Changes in LDL density across the menopausal transition. (2000) (107)
A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity. (1995) (107)
Small, Dense LDL and Elevated Apolipoprotein B Are the Common Characteristics for the Three Major Lipid Phenotypes of Familial Combined Hyperlipidemia (2003) (106)
The visceral adiposity syndrome in Japanese-American men. (1994) (106)
Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss. (2009) (105)
Contribution of Hepatic Lipase, Lipoprotein Lipase, and Cholesteryl Ester Transfer Protein to LDL and HDL Heterogeneity in Healthy Women (2002) (105)
Köbberling type of familial partial lipodystrophy: an underrecognized syndrome. (2003) (104)
Hepatic lipase: a marker for cardiovascular disease risk and response to therapy (2003) (103)
Acquired hyperlipidemia (secondary dyslipoproteinemias). (1990) (103)
A major insertion accounts for a significant proportion of mutations underlying human lipoprotein lipase deficiency. (1989) (100)
Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia. (1987) (99)
Metabolism of very-low-density lipoprotein triglyceride by human placental cells: the role of lipoprotein lipase. (1992) (98)
Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype. (1994) (97)
Relationship between lipoprotein lipase activity and plasma sex steroid level in obese women. (1988) (97)
Paraoxonase genotypes, lipoprotein lipase activity, and HDL. (1996) (96)
Lipoprotein distribution in the metabolic syndrome, type 2 diabetes mellitus, and familial combined hyperlipidemia. (2003) (96)
Compositional differences of LDL particles in normal subjects with LDL subclass phenotype A and LDL subclass phenotype B. (1996) (91)
Abnormal lipoprotein-lipase-mediated plasma triglyceride removal in untreated diabetes mellitus associated with hypertriglyceridemia. (1979) (90)
Effect of a Fat Free, High Carbohydrate Diet on Diabetic Subjects with Fasting Hyperglycemia (1974) (90)
Relationship of family history of type 2 diabetes, hypoglycemia, and autoantibodies to weight gain and lipids with intensive and conventional therapy in the Diabetes Control and Complications Trial. (2003) (87)
Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241. (1992) (87)
Reversible abnormalities in postheparin lipolytic activity during the late phase of release in diabetes mellitus (postheparin lipolytic activity in diabetes). (1975) (86)
Lifestyle and metformin treatment favorably influence lipoprotein subfraction distribution in the Diabetes Prevention Program. (2013) (83)
Prevalence of Severe Arteriosclerosis Obliterans in Patients with Diabetes Mellitus: Relation to Smoking and Form of Therapy (1982) (80)
LDL physical and chemical properties in familial combined hyperlipidemia. (1995) (80)
The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity. (1994) (80)
Molecular basis of familial chylomicronemia: mutations in the lipoprotein lipase and apolipoprotein C-II genes. (1992) (80)
Reversal of decreased human adipose tissue lipoprotein lipase and hypertriglyceridemia after treatment of hypothyroidism. (1976) (79)
Partial gene duplication involving exon-Alu interchange results in lipoprotein lipase deficiency. (1990) (79)
A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women. (1999) (78)
Low Clusterin Levels in High-Density Lipoprotein Associate With Insulin Resistance, Obesity, and Dyslipoproteinemia (2010) (78)
Evidence for kinetic heterogeneity among human low density lipoproteins. (1986) (78)
Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia. (1992) (77)
Chylomicronemia Syndrome in Diabetes Mellitus (1981) (77)
Patients with apoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291-->Ser mutation in the human LPL gene. (1995) (76)
Congenital generalized lipodystrophy accompanied by cystic angiomatosis. (1968) (76)
Molecular genetics of apolipoproteins and coronary heart disease. (1986) (75)
Evidence for diabetes mellitus and genetic forms of hypertriglyceridemia as independent entities. (1975) (75)
TYPE-III HYPERLIPOPROTEINÆMIA ("REMNANT REMOVAL DISEASE") Insight into the Pathogenetic Mechanism (1977) (74)
Severe hypertriglyceridemia: role of familial and acquired disorders. (1983) (72)
Varying Cost and Free Nicotinic Acid Content in Over-the-Counter Niacin Preparations for Dyslipidemia (2003) (72)
Visceral obesity, hepatic lipase activity, and dyslipidemia in type 1 diabetes. (2003) (69)
Dimeric lipoprotein lipase is bound to triglyceride-rich plasma lipoproteins. (1996) (69)
Testosterone administration to men increases hepatic lipase activity and decreases HDL and LDL size in 3 wk. (2003) (68)
Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone. (2004) (68)
Mutagenesis in four candidate heparin binding regions (residues 279-282, 291-304, 390-393, and 439-448) and identification of residues affecting heparin binding of human lipoprotein lipase. (1994) (66)
Familial Lipoprotein Lipase Deficiency (2011) (66)
Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease. (1996) (65)
Gender and elevated albumin excretion in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort: role of central obesity. (2006) (65)
PLTP activity in premenopausal women. Relationship with lipoprotein lipase, HDL, LDL, body fat, and insulin resistance. (2000) (65)
Gene-environment interaction in the conversion of a mild-to-severe phenotype in a patient homozygous for a Ser172-->Cys mutation in the lipoprotein lipase gene. (1993) (64)
Therapeutic response to medium-chain triglycerides and omega-3 fatty acids in a patient with the familial chylomicronemia syndrome. (1997) (64)
Impaired very low density lipoprotein and triglyceride removal in broad beta disease: comparison with endogenous hypertriglyceridemia. (1978) (63)
Effect of dietary fructose on triglyceride transport and glucoregulatory hormones in hypertriglyceridemic men. (1979) (62)
Amino acid substitution (Ile194----Thr) in exon 5 of the lipoprotein lipase gene causes lipoprotein lipase deficiency in three unrelated probands. Support for a multicentric origin. (1991) (61)
Heterogeneity of primary lipoprotein lipase deficiency. (1980) (58)
In vivo evidence of a role for hepatic lipase in human apoB-containing lipoprotein metabolism, independent of its lipolytic activity. (2000) (58)
Pathophysiology of lipoprotein transport. (1978) (57)
Circulating vitamin D metabolites and kidney disease in type 1 diabetes. (2012) (57)
Development of lipoprotein lipase in cultured 3T3-L1 cells. (1977) (57)
Identification of two separate allelic mutations in the lipoprotein lipase gene of a patient with the familial hyperchylomicronemia syndrome. (1991) (57)
Plasma triglyceride levels and coronary disease. (1989) (57)
INCREASED ADIPOSE-TISSUE LIPOPROTEIN-LIPASE ACTIVITY IN MODERATELY OBESE MEN AFTER WEIGHT REDUCTION (1978) (57)
Lipoprotein lipaseBethesda: a single amino acid substitution (Ala-176----Thr) leads to abnormal heparin binding and loss of enzymic activity. (1990) (56)
Genetic variants affecting human lipoprotein and hepatic lipases (1991) (56)
Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex. (1998) (56)
Lipoprotein Lipase Bound to Apolipoprotein B Lipoproteins Accelerates Clearance of Postprandial Lipoproteins in Humans (2006) (55)
Assessment of energy expenditure in ambulatory reduced-obese subjects by the techniques of weight stabilization and exogenous weight replacement. (1990) (54)
The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype. (2012) (54)
Mutations in the lipoprotein lipase gene associated with ischemic heart disease in men. The Copenhagen city heart study. (1999) (54)
Functional characterization of a chimeric lipase genetically engineered from human lipoprotein lipase and human hepatic lipase. (1993) (54)
A novel A-->G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency. (1996) (54)
The central role of dietary fat, not carbohydrate, in the insulin resistance syndrome (1997) (53)
Lipoprotein and apolipoprotein abnormalities in familial combined hyperlipidemia: a 20-year prospective study. (2001) (53)
Increased small dense LDL and intermediate-density lipoprotein with albuminuria in type 1 diabetes. (1999) (53)
Use of Fructose, Xylitol, or Sorbitol as a Sweetener in Diabetes Mellitus (1978) (52)
On the mechanism of action of atromid-S on triglyceride transport in man. (1970) (52)
Detailed characterization of the binding site of the lipoprotein lipase-specific monoclonal antibody 5D2. (1998) (51)
Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis. (2015) (50)
Coexistence of abnormalities of hepatic lipase and lipoprotein lipase in a large family. (1990) (50)
Free fatty acids in the pancreatitic arthritis syndrome. (1983) (48)
Basal and stimulated hyperinsulinism: reversible metabolic sequelae of obesity. (1974) (47)
Effect of heparin on insulin-glucose interactions measured by the minimal model technique: implications for reproducibility using this method. (1993) (46)
Lipoprotein lipase gene expression in THP-1 cells. (1989) (45)
Linkage of low-density lipoprotein size to the lipoprotein lipase gene in heterozygous lipoprotein lipase deficiency. (1999) (45)
Apoprotein measurements and their clinical application. (1989) (45)
Use of niacin, statins, and resins in patients with combined hyperlipidemia. (1998) (44)
Availability of apolipoprotein CII in relation to the maximal removal capacity for an infused triglyceride emulsion in man. (1979) (44)
Distribution of apolipoprotein(a) in the plasma from patients with lipoprotein lipase deficiency and with type III hyperlipoproteinemia. No evidence for a triglyceride-rich precursor of lipoprotein(a). (1992) (44)
Adipose tissue lipoprotein lipase and weight loss. (1984) (43)
Mapping of the epitope on lipoprotein lipase recognized by a monoclonal antibody (5D2) which inhibits lipase activity. (1992) (43)
The interaction of familial and secondary causes of hypertriglyceridemia: role in pancreatitis. (2012) (43)
Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans: role of central obesity and LIPC polymorphisms. (2004) (41)
Lack of evidence for linkage between low‐density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia (1991) (41)
Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. (2013) (40)
Two naturally occurring mutations at the first and second bases of codon aspartic acid 156 in the proposed catalytic triad of human lipoprotein lipase. In vivo evidence that aspartic acid 156 is essential for catalysis. (1992) (40)
Adipose tissue fatty acid composition in humans with lipoprotein lipase deficiency. (2001) (39)
Treatment options for hypertriglyceridemia: from risk reduction to pancreatitis. (2014) (39)
Low-Density Lipoprotein Particle Size Loci in Familial Combined Hyperlipidemia: Evidence for Multiple Loci From a Genome Scan (2004) (39)
Risk factors for cardiovascular disease: renewed interest in triglycerides (2013) (39)
Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene. (2002) (38)
Prevention of raised low-density lipoprotein cholesterol in a patient with familial hypercholesterolaemia and lipoprotein lipase deficiency (1993) (37)
Homozygosity for two point mutations in the lipoprotein lipase (LPL) gene in a patient with familial LPL deficiency: LPL(Asp9-->Asn, Tyr262-->His). (1996) (37)
Hepatic Lipase as a Focal Point for the Development and Treatment of Coronary Artery Disease (2001) (37)
PLTP activity decreases with weight loss: changes in PLTP are associated with changes in subcutaneous fat and FFA but not IAF or insulin sensitivity. (2003) (36)
Insulin and adipose tissue lipoprotein lipase activity in humans. (1981) (36)
Postprandial adipose tissue lipoprotein lipase activity in primary hypertriglyceridemia. (1980) (35)
Dietary fat and obesity. (1999) (35)
Primary lipoprotein lipase deficiency. (1986) (35)
Circulating Vitamin D Metabolites and Subclinical Atherosclerosis in Type 1 Diabetes (2013) (35)
Recurrent pancreatitis and chylomicronemia in an extended Dutch kindred is caused by a Gly154-->Ser substitution in lipoprotein lipase. (1993) (34)
Genetics of apolipoprotein B and apolipoprotein AI and premature coronary artery disease (2006) (34)
The Effect of Excess Weight Gain With Intensive Diabetes Mellitus Treatment on Cardiovascular Disease Risk Factors and Atherosclerosis in Type 1 Diabetes MellitusClinical Perspective (2013) (34)
Lipoprotein Lipase (LPL) is Associated with Neurite Pathology and Its Levels Are Markedly Reduced in the Dentate Gyrus of Alzheimer’s Disease Brains (2013) (34)
Conversion of plasma VLDL and IDL precursors into various LDL subpopulations using density gradient ultracentrifugation. (1990) (33)
Cigarettes smoking and adipose tissue lipoprotein lipase. (1980) (33)
Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency. (2016) (33)
Bacterial lipopolysaccharide reduces macrophage lipoprotein lipase levels: an effect that is independent of tumor necrosis factor. (1988) (31)
Genetic and nongenetic sources of variation in phospholipid transfer protein activity[S] (2010) (31)
Increased ApoB in small dense LDL particles predicts premature coronary artery disease. (2005) (30)
Selective and independent associations of phospholipid transfer protein and hepatic lipase with the LDL subfraction distribution DOI 10.1194/jlr.M100373-JLR200 (2002) (30)
Plasma triglyceride and insulin levels in familial hypertriglyceridemia. (1977) (29)
Structure-function relationships of lipoprotein lipase: mutation analysis and mutagenesis of the loop region. (1993) (29)
Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment (2003) (29)
Frameshift mutation in exon 3 of the lipoprotein lipase gene causes a premature stop codon and lipoprotein lipase deficiency. (1990) (29)
Genetic effects in human energy expenditure components : genetic effects may contribute to an explantion of the heterogeneity in energy expenditure between individuals. Commentary (1990) (28)
Human Adipose Tissue Lipoprotein Lipase: Comparison of Assay Methods and Expressions of Activity 1 (1975) (27)
Characterization of a lipoprotein lipase class III type defect in hypertriglyceridemic cats. (1990) (26)
Recurrent missense mutations at the first and second base of codon Arg243 in human lipoprotein lipase in patients of different ancestries (1994) (26)
Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: kinetic analysis using an integrated model. (1986) (26)
Low-density and high-density lipoprotein subspecies and risk for premature coronary artery disease. (1999) (26)
Insulin regulation of lipoprotein lipase in cultured 3T3-L1 cells. (1978) (26)
Studies on the Placental Hydrolysis and Transfer of Lipids to the Fetal Guinea Pig (1984) (25)
Reduction of plasma triglyceride concentration by acute stress in man. (1979) (25)
Relationships between LDL density and kinetic heterogeneity in subjects with normolipidemia and familial combined hyperlipidemia using density gradient ultracentrifugation. (1989) (24)
DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes (2020) (24)
Chylomicronemia syndrome. (1992) (24)
Effect of phenformin on lipid transport in hypertriglyceridemia. (1974) (24)
Effects of niacin combination therapy with statin or bile acid resin on lipoproteins and cardiovascular disease. (2014) (24)
Effects of transdermal estrogen on levels of lipids, lipase activity, and inflammatory markers in men with prostate cancer Published, JLR Papers in Press, November 20, 2005. (2006) (23)
Regulation of body adiposity and the problem of obesity. (1997) (23)
Intraabdominal fat, insulin sensitivity, and cardiovascular risk factors in postpartum women with a history of preeclampsia. (2015) (23)
Rosiglitazone increases LDL particle size and buoyancy and decreases C-reactive protein in patients with type 2 diabetes on statin therapy (2006) (23)
Lipoprotein lipase and hepatic lipase: their relationship with HDL subspecies Lp(A-I) and Lp(A-I,A-II). (2003) (23)
Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300272-JLR200 (2003) (22)
Elevated adipose tissue lipoprotein lipase in the pathogenesis of obesity in the Prader-Willi syndrome. (1979) (22)
Intra-abdominal fat accumulation is greatest at younger ages in Japanese-American adults. (2010) (22)
Effect of raloxifene on serum triglycerides in women with a history of hypertriglyceridemia while on oral estrogen therapy. (2005) (21)
Genome scan for quantitative trait loci influencing HDL levels: evidence for multilocus inheritance in familial combined hyperlipidemia (2005) (21)
Paradoxical hypoinsulinaemia: an alpha-adrenergic-mediated response to glucose. (1972) (19)
A missense mutation Pro157 Arg in lipoprotein lipase (LPLNijmegen) resulting in loss of catalytic activity. (1992) (19)
HDL in CKD: how good is the "good cholesterol?". (2014) (19)
Potential of essential fatty acid deficiency with extremely low fat diet in lipoprotein lipase deficiency during pregnancy: A case report (2004) (18)
Erratum: Increased small dense LDL and intermediate-density lipoprotein with albuminuria in type 1 diabetes (Diabetes Case (1999) 22 (1165-1170)) (1999) (17)
PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity1[S] (2015) (17)
Phenotypic variation of mutations in the human lipoprotein-lipase gene. (1993) (16)
Obesity and common genetic metabolic disorders. (1985) (16)
LDL composition in E2/2 subjects and LDL distribution by Apo E genotype in type 1 diabetes. (2007) (15)
Molecular genetics of apoC-II and lipoprotein lipase deficiency. (1991) (15)
Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid‐lowering therapy (2006) (14)
The effects of diuretics and adrenergic-blocking agents on plasma lipids. (1986) (14)
Comparison of Methods of Plasma Triglyceride Turnover (1977) (14)
Linkage and association of phospholipid transfer protein activity to LASS4[S] (2011) (14)
of the National Heart , Lung , and Blood Institute – National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Cardiovascular Complications of Type 1 Diabetes Mellitus (2005) (14)
Proteinuria and lipoprotein lipase activity in Miniature Schnauzer dogs with and without hypertriglyceridemia. (2016) (13)
Human adipose tissue lipoprotein lipase (1985) (13)
The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy (2009) (13)
Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families (2010) (12)
Obesity and coronary heart disease. A targeted approach. (1984) (12)
Effect of controlled alcohol feeding on triglycerides in patients with outpatient 'alcohol hypertriglyceridemia'. (1980) (11)
Hepatic lipase and dyslipidemia Published, JLR Papers in Press, March 16, 2003. DOI 10.1194/jlr.R200017-JLR200 (2003) (11)
Pathophysiology of hyperlipidemia in diabetes mellitus. Discussion (1990) (11)
Frequent detection of familial hypercholesterolemia mutations in familial combined hyperlipidemia. (2008) (11)
Body fat distribution and dyslipidemia. (1995) (11)
The Effect of Excess Weight Gain with Intensive Diabetes Treatment on Cardiovascular Disease Risk Factors and Atherosclerosis in Type 1 Diabetes: Results from the Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC) Study (2012) (10)
Hormonal Regulation of Human Adipose Tissue Lipoprotein Lipase (1977) (10)
Retroviral-mediated gene transfer and expression of human lipoprotein lipase in somatic cells. (1995) (9)
Genetic Disorders of Triglyceride Metabolism (2015) (9)
Effect of in-vitro lifespan of 3T3-L1 cells on hormonal responsiveness of lipoprotein lipase activity. (1981) (9)
Effect of Phenformin on Glucose-Insulin Interrelationships (1974) (9)
Association of apolipoprotein B gene variants with plasma apoB and low density lipoprotein (LDL) cholesterol levels (1992) (8)
421 ENERGY BALANCE IN CONGENITAL GENERALIZED LIPODYSTROPHY TYPE I. (2004) (8)
Albuminuria, the HDL (High-Density Lipoprotein) Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus. (2019) (8)
Red Cell Oxygen Affinity in Severe Hypertriglyceridemia 1 (1978) (8)
ApoE enhances lipid uptake by macrophages in lipoprotein lipase deficiency during pregnancy. (1996) (7)
Patient information page from The Hormone Foundations. Patient guide to the assessment and treatment of hypertriglyceridemia (high triglycerides). (2012) (7)
A 4 basepair deletion in exon 4 of the human lipoprotein lipase gene results in type I hyperlipoproteinemia. (1993) (7)
Familial Combined Hyperlipidemia and Familial Hypertriglyceridemia (1987) (7)
Host and environmental effects on plasma apolipoprotein B (1993) (6)
Familial hypocalciuric hypercalcaemia--familial benign hypercalcaemia: a review. (1987) (6)
The Kinetics and Remodeling of HDL Particles: Lessons from Inborn Errors of Lipid Metabolism (2010) (6)
Metabolic consequences of genetic heterogeneity of lipoprotein composition (lipoprotein heterogeneity). (1987) (5)
Successful desensitization to rosuvastatin in a patient with a history of anaphylaxis to multiple statins. (2013) (5)
Use of fructose, sorbitol, or xylitol as a sweetener in diabetes mellitus. (1978) (5)
Triglyceride abnormality in infantile hypothyroidism. (1973) (5)
Are all obese patients at risk for cardiovascular disease? (1984) (5)
Disease Risk Type 2 Diabetes and Familial Combined Hyperlipidemia in Coronary Artery Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome : Importance of Society (2004) (5)
Lipoprotein Metabolism: Structure and Function (2003) (4)
Effects of carbohydrate deprivation. (1972) (4)
A-l and Coronary Artery Disease in Humans (2005) (4)
1.P.58 Hepatic lipase mediated changes in LDL density predict coronary stenosis regression in the familial atherosclerosis treatment study (1997) (4)
A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia: response to Goldberg et al. (2005) (4)
Oxidative Stress and Cardiovascular Risk in Type 1 Diabetes Mellitus: Insights From the DCCT/EDIC Study (2018) (4)
Effect of intensive diabetes therapy on diabetic dyslipidemia (1997) (4)
4 – Very Low Density Lipoprotein Kinetics in Familial Forms of Hypertriglyceridemia (1982) (3)
Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome. (2005) (3)
1124-192 Rosiglitazone reduces novel biomarkers of cardiovascular disease in subjects with type 2 diabetes mellitus already on statin therapy (2004) (3)
Measurement of human lipoprotein lipase (LPL) by enzyme-linked immunosorbent assay (ELISA) using a single monoclonal antibody (1985) (3)
1.P.42 Small, dense LDL is associated with low lipoprotein lipase and high hepatic lipase activities, and alterations in IDL and VLDL composition (1997) (3)
Effect of dietary fructose on triglyceride transport and glucoregulatory hormones in hypertriglyceridemic subjects (1977) (3)
DIETARY FAT AND OBESITY. AUTHORS' REPLIES (1999) (3)
Endogenous hypertriglyceridemia: a splanchnic defect, hyperinsulinism, or both? (1981) (2)
Treatment Is Indicated because of the Risk of Accelerated Atherosclerosis (1993) (2)
Steroid contraceptives and human lipoprotein metabolism: effects and mechanisms. (1977) (2)
AHA Conference Report on Cholesterol. Diagnosis, evaluation, and treatment: current status and issues. (1989) (2)
A comparison of triglyceride, monoglyceride, and phospholipid substrates for post-heparin lipolytic activities from normal and hypertriglyceridemic subjects (1971) (2)
Weight gain trajectories and obesity rates in intensive and conventional treatments of type 1 diabetes from the DCCT compared with a control population without diabetes (2022) (2)
DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes (2020) (2)
Long-term Renal Outcomes of Patients With Type 1 Diabetes Mellitus and Microalbuminuria: An Analysis of the DCCT/EDIC Cohort—Reply (2011) (2)
Treatment of hypertriglyceridemia with para-aminosalicylic acid-C: a possible mechanism of action. (1978) (2)
A Comparative Evaluation of Two Scales Used in the Assessment of Adult Attention Deficit Hyperactivity Disorder (2011) (2)
Chylomicronemia induced by cimetidine. (1985) (2)
Diet Low in Saturated Fat and Cholesterol for Diabetes (1989) (2)
Individuality, hyperlipidemia, and premature coronary artery disease. (1990) (2)
Lipoprotein-Lipase Deficiency: Treatment with Omega-3 Fatty Acids and Colestyramine for Severe Gestational Hypertriglyceridaemia and Follow up over Twenty Years (2013) (1)
PLTP activity decreases with weight loss Published, JLR Papers in Press, July 1, 2003. DOI 10.1194/jlr.M300073-JLR200 (2003) (1)
Understanding the Basis of Biologic Variance in the Obesity/Diabetes/Cardiovascular Disease Connection Obesity, Body Fat Distribution, Insulin Sensitivity and Islet b -Cell Function as Explanations for Metabolic Diversity 1,2 (2001) (1)
ENERGY BALANCE IN CONGENITAL GENERALIZED LIPODYSTROPHY TYPE I.: 421 (2004) (1)
Retroviral-mediated gene transfer and expression of human lipoprotein lipase (LPL) in somatic cells (1994) (1)
Status of "familial combined hyperlipidemia". (1984) (1)
4 THE TRANSITION THROUGH MENOPAUSE LEADS TO RAPID SHIFTS IN BODY FAT DISTRIBUTION AND LIPID METABOLISM: THE MIDLIFE CHOLESTEROL STUDY (2004) (1)
Weight gain accompanying intensive diabetes therapy in type I diabetes is associated with higher levels of dense LDL cholesterol (1996) (1)
Lipoprotein abnormalities in diabetes mellitus. (1992) (1)
Genomewide Scan for Quantitative Trait Loci Influencing Low-density Lipoprotein Size and Plasma Triglyceride in Familial Hypertriglyceridemia (2003) (1)
Peripheral vascular disease after kidney-pancreas transplantation (1996) (1)
Twenty-year cardiovascular disease mortality in the familial forms of hypertriglyceridemia (2000) (1)
Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans Published, JLR Papers in Press, December 1, 2003. DOI 10.1194/jlr.M300295-JLR200 (2004) (1)
Can a defect in thermogenesis cause obesity? Commentary (1990) (1)
1.P.319 A common mutation T(−93)→G in the promoter of the lipoprotein lipase gene is associated with elevated plasma triglycerides in both genders and with ischemic heart disease in men. The Copenhagen City Heart Study (1997) (1)
Lipoprotein profiles in transgenic mice expressing human lipoprotein lipase on a regular and high fat diet (1994) (1)
Lipoprotein lipase and hepatic lipase Published, JLR Papers in Press, June 1, 2003. DOI 10.1194/jlr.M300091-JLR200 (2003) (1)
Plasma lipids and lipoprotein lipase activity in Kawasaki syndrome (KS) (1992) (1)
Premature coronary artery disease and apolipoprotein B and apolipoprotein A-I (2007) (1)
Family history of type 2 diabetes predicts excess weight gain in type 1 diabetic patients on intensive therapy (1999) (0)
Familial combined hyperlipidemia: an oligogenic disorder (2010) (0)
Triglycerides and coronary heart disease. (1980) (0)
Workshop IV: Diagnosis, evaluation, and treatment: Current status and issues (1989) (0)
Diagnosis of Dyslipidemia (2020) (0)
Lipase Activity With Increasing Intra-abdominal Fat in Women A Hepatic Lipase Gene Promoter Polymorphism Attenuates the Increase in Hepatic (1999) (0)
Figure 3, [Lipemia retinalis. Note the pale color of the retinal vessels.]. (2015) (0)
240: Women with a history of preeclampsia have an atherogenic lipid profile and endothelial dysfunction but no difference in adiposity or insulin sensitivity (2008) (0)
The interaction of familial and secondary causes of hypertriglyceridemia: role in pancreatitis. (2010) (0)
INPATIENT MANAGEMENT OF ADULTS WITH DIABETES. AUTHORS' REPLY (1996) (0)
Table 1, Definition of hypertriglyceridemia according to various clinical guidelines (2015) (0)
lipase activity and decreases HDL and LDL size in 3 wk Testosterone administration to men increases hepatic (2016) (0)
Uremic hyperlipidemia: the nature of the problem. (1977) (0)
CHAPTER 6 – Genetic Dyslipidemia (2009) (0)
The metabolic syndrome: components and consequences in 4 species (2013) (0)
Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia (1980) (0)
Preventive Cardiology AbstractsCommon hepatic lipase gene promoter variant determines clinical response to intensive lipid lowering therapy (2001) (0)
Effect of concurrent LDL receptor gene and LPL gene mutations on LDL particles size, density and lipid composition (1999) (0)
Figure 2, [Eruptive xanthomas. The commonest site...]. (2015) (0)
Familial hyperlipoproteinemias and the metabolism of triglyceride-rich lipoproteins (1989) (0)
Taenia in the Gastrointestinal Tract (2008) (0)
EFFECT OF COMBINED KIDNEY-PANCREAS TRANSPLANT ON THE LIPID PROFILE: ONE YEAR FOLLOW-UP (1998) (0)
Table 2, Selected genes with roles in FCHL (2015) (0)
PRESCRIBING PRACTICES FOR PAINFUL DIABETIC NEUROPATHY (2008) (0)
Response to Matz (1996) (0)
Hormone health network's (2012) (0)
Abstract: 1516 LIPID AND GLUCOSE TARGETS IN DIABETES AND FAMILIAL COMBINED HYPERLIPIDEMIA (2009) (0)
The author replies [10] (2008) (0)
The use of twins in obesity research (1990) (0)
419 THE TRANSITION THROUGH MENOPAUSE LEADS TO RAPID SHIFTS IN BODY FAT DISTRIBUTION AND LIPID METABOLISM: THE MIDLIFE CHOLESTEROL STUDY. (2004) (0)
Thanks to Reviewers2003 (2003) (0)
Central obesity, hepatic lipase activity and dyslipidemia in type 1 diabetes (1999) (0)
Hormone health network's: Patient guide to the assessment and treatment of hypertriglyceridemia (high triglycerides) (2012) (0)
Genetic variation in triglyceride metabolism and atherogenesis (1994) (0)
Localization by genome scan of two large QTLs influencing HDL levels in FCHL pedigrees with exploration of their relationship to triglyceride levels (2002) (0)
Consensus Reports (2011) (0)
Do lipoprotein subclass tests increase treatment rates in high-risk patients? (2003) (0)
Table 4, Secondary causes that can contribute to severe HTG (2015) (0)
Chylomicronemia Syndrome: Very Severe Hypertriglyceridemia and Acute Pancreatitis (2014) (0)
I n c reased Small Dense LDL and I n t e rm e d i a te-D e n s ity Lip o p ro t e i n Wi t h Albuminuria in Type 1 Diabetes (1999) (0)
Oligogenic Syndromes Associated with Central Obesity and Insulin Resistance: Models for Polycystic Ovary Syndrome (2002) (0)
A role for endogenous alpha adrenergic activity in abnormal insulin secretion in diabetics (1975) (0)
INSULIN RESISTANCE AND TYPE 2 DIABETES: IMPROVING INSULIN RESISTANCE IN TYPE 2 DIABETES NORMALIZES LDL PARTICLE DISTRIBUTION (2008) (0)
Table 1. [Summary of Molecular Genetic Testing Used in Familial Lipoprotein Lipase Deficiency]. (2011) (0)
Phospholipid transfer protein activity decreases with weight loss: Changes in PLTP are associated with changes in subcutaneous fat and non-esterified fatty acids but not with intra- abdominal fat or insulin sensitivity. (2003) (0)
Figure 1, Palmar Xanthomas: Note the orange-yellow discoloration confined to the palmar creases. (2015) (0)
Abstract: S3-10 ROLE OF HEPATIC LIPASE IN HDL METABOLISM AND CAD (2009) (0)
Conference Report From the American Diabetes Association and the Lipoprotein Management in Patients With Cardiometabolic Risk: Consensus (2008) (0)

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