J. David Jentsch
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American neuroscientist
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Why Is J. David Jentsch Influential?
(Suggest an Edit or Addition)According to Wikipedia, James David Jentsch is an American neuroscientist. He is the Empire Innovation Professor of Psychology at Binghamton University. His research considers the neurobiological origins of psychoses and addiction. Jentsch was awarded the 2011 AAAS Award for Scientific Freedom and Responsibility.
J. David Jentsch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli (1999) (1522)
- The Neuropsychopharmacology of Phencyclidine: From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia (1999) (1286)
- Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. (1997) (411)
- The HMG-CoA Reductase Inhibitor Lovastatin Reverses the Learning and Attention Deficits in a Mouse Model of Neurofibromatosis Type 1 (2005) (389)
- Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal Cortical-Dependent Cognition in the Rat (1997) (328)
- A Neurobehavioral Systems Analysis of Adult Rats Exposed to Methylazoxymethanol Acetate on E17: Implications for the Neuropathology of Schizophrenia (2006) (322)
- Impairments of Reversal Learning and Response Perseveration after Repeated, Intermittent Cocaine Administrations to Monkeys (2002) (270)
- Reversal learning as a measure of impulsive and compulsive behavior in addictions (2011) (237)
- Dopamine and Spatial Working Memory in Rats and Monkeys: Pharmacological Reversal of Stress-Induced Impairment (1996) (237)
- Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice (2007) (235)
- Dissecting impulsivity and its relationships to drug addictions (2014) (224)
- Insight into the relationship between impulsivity and substance abuse from studies using animal models. (2010) (220)
- Neural components underlying behavioral flexibility in human reversal learning. (2010) (168)
- Poor response inhibition: At the nexus between substance abuse and attention deficit/hyperactivity disorder (2009) (166)
- Subchronic Phencyclidine Administration Increases Mesolimbic Dopaminergic System Responsivity and Augments Stress- and Psychostimulant-Induced Hyperlocomotion (1998) (162)
- Δ9-Tetrahydrocannabinol Increases Prefrontal Cortical Catecholaminergic Utilization and Impairs Spatial Working Memory in the Rat: Blockade of Dopaminergic Effects with HA966 (1997) (161)
- Neurofibromin regulates corticostriatal inhibitory networks during working memory performance (2010) (148)
- Dopamine D2/D3 Receptors Play a Specific Role in the Reversal of a Learned Visual Discrimination in Monkeys (2007) (148)
- Nicotine enhances responding with conditioned reinforcement (2003) (141)
- Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits (2012) (127)
- ΔFosB in the Nucleus Accumbens Regulates Food-Reinforced Instrumental Behavior and Motivation (2006) (117)
- Reduced Dysbindin Expression Mediates N-Methyl-D-Aspartate Receptor Hypofunction and Impaired Working Memory Performance (2011) (116)
- Targeted Expression of Mu-Opioid Receptors in a Subset of Striatal Direct-Pathway Neurons Restores Opiate Reward (2014) (114)
- Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. (2013) (113)
- Systems biology of the vervet monkey. (2013) (112)
- In the Blink of an Eye: Relating Positive-Feedback Sensitivity to Striatal Dopamine D2-Like Receptors through Blink Rate (2014) (108)
- Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys (2008) (108)
- Impaired Inhibition of Conditioned Responses Produced by Subchronic Administration of Phencyclidine to Rats (2001) (107)
- Dysbindin Modulates Prefrontal Cortical Glutamatergic Circuits and Working Memory Function in Mice (2009) (101)
- Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence (1998) (99)
- Repeated nicotine exposure enhances responding with conditioned reinforcement (2004) (98)
- Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals (2011) (98)
- Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action. (2000) (97)
- Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits (1999) (93)
- Repeated Nicotine Exposure Enhances Reward-Related Learning in the Rat (2003) (93)
- Genetic Dissection of Behavioral Flexibility: Reversal Learning in Mice (2011) (91)
- The relationship between measures of impulsivity and alcohol misuse: an integrative structural equation modeling approach. (2012) (90)
- Dysregulation of D2-Mediated Dopamine Transmission in Monkeys after Chronic Escalating Methamphetamine Exposure (2012) (90)
- Dorsal Striatal D2-Like Receptor Availability Covaries with Sensitivity to Positive Reinforcement during Discrimination Learning (2011) (89)
- Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys (1999) (88)
- Reward, interrupted: Inhibitory control and its relevance to addictions (2014) (88)
- The Alpha-1 Adrenergic Agonist, Cirazoline, Impairs Spatial Working Memory Performance in Aged Monkeys (1997) (87)
- Phencyclidine Increases Forebrain Monoamine Metabolism in Rats and Monkeys: Modulation by the Isomers of HA966 (1997) (84)
- Persistent and anatomically selective reduction in prefrontal cortical dopamine metabolism after repeated, intermittent cannabinoid administration to rats (2003) (83)
- XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome. (2005) (73)
- Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits (2009) (72)
- Sex-related differences in spatial divided attention and motor impulsivity in rats. (2003) (72)
- Behavioral Characteristics and Neural Mechanisms Mediating Performance in a Rodent Version of the Balloon Analog Risk Task (2010) (69)
- Monoamine Levels Within the Orbitofrontal Cortex and Putamen Interact to Predict Reversal Learning Performance (2013) (55)
- Alpha-2 Adrenoceptor Activation Inhibits Phencyclidine-Induced Deficits of Spatial Working Memory in Rats (2005) (54)
- Shaping vulnerability to addiction – the contribution of behavior, neural circuits and molecular mechanisms (2018) (53)
- Cocaine self-administration behavior in inbred mouse lines segregating different capacities for inhibitory control (2013) (52)
- Cannabinoid CB1 receptor-mediated impairment of visuospatial attention in the rat (2004) (52)
- Methamphetamine-induced increases in putamen gray matter associate with inhibitory control (2013) (51)
- A non-human primate system for large-scale genetic studies of complex traits. (2012) (50)
- Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate. (2016) (48)
- Effects of atomoxetine and methylphenidate on performance of a lateralized reaction time task in rats (2008) (48)
- Repeated, Intermittent Δ9-Tetrahydrocannabinol Administration to Rats Impairs Acquisition and Performance of a Test of Visuospatial Divided Attention (2004) (47)
- Dimensions of Impulsivity Are Associated with Poor Spatial Working Memory Performance in Monkeys (2007) (46)
- Behavioral impairments in rats with chronic epilepsy suggest comorbidity between epilepsy and attention deficit/hyperactivity disorder (2014) (44)
- Impaired visuospatial divided attention in the spontaneously hypertensive rat (2005) (42)
- Low circulating levels of bisphenol‐A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys (2015) (40)
- Risk-taking and alcohol use disorders symptomatology in a sample of problem drinkers. (2011) (37)
- Consideration of species differences in developing novel molecules as cognition enhancers (2013) (35)
- A low dose of the alpha2 agonist clonidine ameliorates the visual attention and spatial working memory deficits produced by phencyclidine administration to rats (2004) (34)
- Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration (2012) (34)
- Cognitive control and the dopamine D2‐like receptor: a dimensional understanding of addiction (2012) (34)
- Genetic, hormonal, and metabolomic influences on social behavior and sex preference of XXY mice. (2010) (33)
- Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs (2001) (32)
- Effect of acute and repeated treatment with desipramine or methylphenidate on serial reversal learning in rats (2009) (30)
- Haploinsufficiency of the arginine–vasopressin gene is associated with poor spatial working memory performance in rats (2006) (30)
- Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia. (1998) (27)
- Differences in the subjective and motivational properties of alcohol across alcohol use severity: application of a novel translational human laboratory paradigm (2018) (26)
- Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice (2018) (26)
- Dysbindin‐1 loss compromises NMDAR‐dependent synaptic plasticity and contextual fear conditioning (2014) (26)
- Potential molecular mechanisms for decreased synaptic glutamate release in dysbindin-1 mutant mice (2013) (25)
- Opioid self-administration results in cell-type specific adaptations of striatal medium spiny neurons (2013) (25)
- Clozapine Normalizes Prefrontal Cortex Dopamine Transmission in Monkeys Subchronically Exposed to Phencyclidine (2008) (25)
- Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia (2013) (25)
- Reward, Relief and Habit Drinking: Initial Validation of a Brief Assessment Tool. (2019) (24)
- Null Mutation of the Arginine-Vasopressin Gene in Rats Slows Attentional Engagement and Facilitates Response Accuracy in a Lateralized Reaction Time Task (2003) (22)
- Modeling behavioral reactivity to losses and rewards on the Balloon Analogue Risk Task (BART): moderation by alcohol problem severity. (2014) (21)
- Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine (2020) (21)
- Responding in a test of decision-making under risk is under moderate genetic control in the rat. (2012) (20)
- Structural and functional neuroimaging phenotypes in dysbindin mutant mice (2012) (19)
- Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens (2013) (18)
- Genetic Vasopressin Deficiency Facilitates Performance of a Lateralized Reaction-Time Task: Altered Attention and Motor Processes (2003) (17)
- Primate Phencyclidine Model of Schizophrenia: Sex-Specific Effects on Cognition, Brain Derived Neurotrophic Factor, Spine Synapses, and Dopamine Turnover in Prefrontal Cortex (2015) (16)
- Recognition deficits in mice carrying mutations of genes encoding BLOC‐1 subunits pallidin or dysbindin (2015) (16)
- Establishing orally self-administered cocaine as a reinforcer in rats using home-cage pre-exposure (1998) (16)
- The future of translational research on alcohol use disorder (2020) (15)
- Pre-clinical models of cognitive dysfunction in schizophrenia: new avenues to addressing unmet needs (2003) (15)
- Impulsivity in Animal Models for Drug Abuse Disorders. (2008) (15)
- Stimulant effects on striatal and cortical dopamine systems involved in reward-related behavior and impulsivity. (2001) (14)
- Steep effort discounting of a preferred reward over a freely-available option in prolonged methamphetamine withdrawal in male rats (2017) (13)
- Identifying the molecular basis of inhibitory control deficits in addictions: neuroimaging in non-human primates (2013) (12)
- Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex. (1998) (11)
- Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel (2021) (10)
- Heritability of ethanol consumption and pharmacokinetics in a genetically diverse panel of Collaborative Cross mouse strains and their inbred founders (2020) (10)
- Extreme phenotypic diversity in operant response to intravenous cocaine or saline infusion in the hybrid mouse diversity panel (2022) (10)
- Prospects for finding the mechanisms of sex differences in addiction with human and model organism genetic analysis (2020) (10)
- Changes in Imaging and Cognition in Juvenile Rats After Whole-Brain Irradiation (2016) (9)
- Compromised NMDA/Glutamate Receptor Expression in Dopaminergic Neurons Impairs Instrumental Learning, But Not Pavlovian Goal Tracking or Sign Tracking1,2,3 (2015) (9)
- Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primate (2016) (8)
- Phencyclidine Model of Frontal Cortical Dysfunction in Nonhuman Primates (2000) (7)
- Consideration of genetic and sex effects in mice enhances consilience with human addiction studies (2020) (6)
- Stimulant-associated cognitive abnormalities: mechanisms and impact on reward-related behavior and addiction. (2008) (6)
- The Absence of Blocking Innicotine High-Responders as a Possible Factor in the Development of Nicotine Dependence? (2014) (5)
- Effects of Antipsychotic Drugs on Dopamine Release and Metabolism in the Central Nervous System (2000) (4)
- Extreme Phenotypic Diversity in Operant Responding for an Intravenous Cocaine or Saline Infusion in the Hybrid Mouse Diversity Panel (2021) (4)
- Reversal Learning Performance in the XY∗ Mouse Model of Klinefelter and Turner Syndromes (2019) (4)
- We Must Face the Threats (2009) (4)
- The Neuropsychology of Mental Illness: Cognitive phenomics (2009) (4)
- Are nicotine-related cues susceptible to the blocking effect? (2011) (4)
- Reversal learning performance in the XY* mouse model of Klinefelter and Turner Syndromes (2019) (4)
- Sex chromosome complement affects multiple aspects of reversal‐learning task performance in mice (2020) (4)
- Cognitive Dysfunction in Genetic Mouse Models of Parkinsonism (2011) (2)
- Animal Models of Psychosis (2003) (2)
- Syn3 Gene Knockout Negatively Impacts Aspects of Reversal Learning Performance (2021) (2)
- Genetic variation and sex differences are missed opportunities for addiction biology (2020) (2)
- Widespread genetic effects and sex differences play a crucial role in addiction (2020) (2)
- NMDA receptor hypofunction and animal models of schizophrenia (2000) (1)
- A system for continuous and automated measurement of mouse home-cage drinking with automated control of liquid access (2021) (1)
- Drug-primed reinstatement of cocaine seeking in mice: increased excitability of mediumsized spiny neurons in the nucleus accumbens (2013) (1)
- Gonadal Sex and Sex-Chromosome Complement Interact to Affect Ethanol Consumption in Adolescent Four Core Genotypes Mice (2022) (1)
- Synaptic Transmission: Intercellular Signaling (2007) (1)
- Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice (2022) (1)
- Massively parallel sequencing in >250 families with X-linked intellectual disability (2011) (1)
- Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine (2020) (1)
- P.3.d.019 Asenapine improves cognition and cortical serotonergic function in monkeys with phencyclidine-induced impairment (2009) (1)
- Immunosuppressive effect and global dysregulation of blood transcriptome in response to psychosocial stress in vervet monkeys (Chlorocebus sabaeus) (2020) (1)
- Animal Models of Addiction (2013) (1)
- Monoaminergic Regulation of Cognitive Control in Laboratory Animals (2011) (0)
- 402 TESTICULAR FAILURE AND LEARNING DEFICITS IN ADULT XXY MICE (2005) (0)
- PERSISTENT INCREASES IN CONDITIONED REINFORCEMENT PRODUCED BY MODULATION OF PROTEIN KINASE A IN THE AMYGDALA (1999) (0)
- Reduced Dysbindin Expression Mediates NMDA Receptor Hypofunction and Impaired Working Memory Performance (2014) (0)
- Reversal learning as a measure of impulsive and compulsive behavior in addictions (2011) (0)
- Ways Individual Scientists and Clinicians Can Support Animal Research (2011) (0)
- Highlights Only a subset of people exposed to abused substances go on to develop addiction (2017) (0)
- 1 ACETYLCHOLINE (2002) (0)
- Ac ce pte d M an us cri pt Primate phencyclidine model of schizophrenia : sex-specific effects on cognition , BDNF , spine synapses and dopamine turnover in dorsolateral prefrontal cortex (2014) (0)
- Reversal Learning Phenotypes are Linked with Novel Genetic Loci in Diversity Outbred Mice (2022) (0)
- S10 VASOPRESSINERGIC MECHANISMS IN COGNITION (2005) (0)
- Cannabinoid effects on neurocognition: Implications for psychosis (2002) (0)
- Cocaine self-administration behavior in inbred mouse lines segregating different capacities for inhibitory control (2013) (0)
- Enough is enough. (2009) (0)
- Micein Dopamine Transporter Knock-Down Altered Corticostriatal Neurotransmission and (2015) (0)
- Methamphetamine-induced increases in putamen gray matter associate with inhibitory control (2013) (0)
- Serum lipid levels influence cognitive performance in older vervet monkeys (Chlorocebus aethiops sabaeus) on a long‐term stable diet (2011) (0)
- Cognitive deficits and cortical dopamine dysfunction in a primate model of schizophrenia (1998) (0)
- PCP (Phencyclidine Hydrochloride) (2003) (0)
- Steep effort discounting of a preferred reward over a freely-available option in prolonged methamphetamine withdrawal in male rats (2017) (0)
- The Canadian Consortium for the Investigation of Cannabinoids in Human Therapeutics (2004) (0)
- Sensitivity to feedback in discrimination learning is related to D2/D3 receptor availability in monkeys (2011) (0)
- Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice (2022) (0)
- Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in inbred and recombinant inbred mice (2022) (0)
- Neuron Navigator 1 Regulates Learning, Memory, and the Response to Multiple Potentially Addictive Drugs (2022) (0)
- Synaptic fusions in regulating sleep and wake activity in mice (2017) (0)
- 391. Behavioral consequences of corticostriatal dysfunction produced by phencyclidine administration (2000) (0)
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