James E. Cleaver
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Biology
James E. Cleaver's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is James E. Cleaver Influential?
(Suggest an Edit or Addition)James E. Cleaver's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Defective Repair Replication of DNA in Xeroderma Pigmentosum (1968) (1657)
- Thymidine metabolism and cell kinetics (1967) (627)
- CELL SURVIVAL CHARACTERISTICS AND MOLECULAR RESPONSES OF ANTARCTIC PHYTOPLANKTON TO ULTRAVIOLET‐B RADIATION 1 (1991) (501)
- Cancer in xeroderma pigmentosum and related disorders of DNA repair (2005) (441)
- Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity (2009) (416)
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma (2011) (395)
- Xeroderma pigmentosum: a human disease in which an initial stage of DNA repair is defective. (1969) (394)
- Xeroderma pigmentosum: biochemical and genetic characteristics. (1975) (379)
- High-LET radiations induce a large proportion of non-rejoining DNA breaks (1977) (363)
- Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair. (1969) (353)
- Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. (1999) (350)
- H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks. (2006) (339)
- Temporal dissection of tumorigenesis in primary cancers. (2011) (243)
- Inhibitors of poly(adenosine diphosphate-ribose) synthesis: effect on other metabolic processes. (1984) (237)
- Repair Processes for Photochemical Damage in Mammalian Cells (1974) (234)
- Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells (1977) (234)
- Repair replication, unscheduled DNA synthesis, and the repair of mammalian DNA. (1969) (233)
- Xeroderma pigmentosum: variants with normal DNA repair and normal sensitivity to ultraviolet light. (1972) (232)
- UV damage, DNA repair and skin carcinogenesis. (2002) (232)
- UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization (2001) (228)
- A summary of mutations in the UV‐sensitive disorders: Xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy (1999) (226)
- Single strand interruptions in DNA and the effects of caffeine in Chinese hamster cells irradiated with ultraviolet light. (1969) (217)
- Sequence specificity of cyclobutane pyrimidine dimers in DNA treated with solar (ultraviolet B) radiation. (1992) (198)
- It was a very good year for DNA repair (1994) (188)
- DNA repair and its coupling to DNA replication in eukaryotic cells. (1978) (185)
- A minority of foci or pan-nuclear apoptotic staining of γH2AX in the S phase after UV damage contain DNA double-strand breaks (2010) (184)
- DNA damage and repair in light-sensitive human skin disease. (1970) (180)
- ABSENCE OF EXCISION OF ULTRAVIOLET‐INDUCED CYCLOBUTANE DIMERS IN XERODERMA PIGMENTOSUM * (1970) (176)
- DNA repair and radiation sensitivity in human (xeroderma pigmentosum) cells. (1970) (169)
- Xeroderma pigmentosum and Cockayne syndrome: overlapping clinical and biochemical phenotypes. (1992) (167)
- Repair Replication in HeLa Cells after Large Doses of X-irradiation (1967) (150)
- Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum. (2000) (143)
- DNA-PKcs function regulated specifically by protein phosphatase 5. (2004) (136)
- Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells. (1976) (136)
- Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination (2015) (133)
- Nonrandom induction of pyrimidine-pyrimidone (6-4) photoproducts in ultraviolet-irradiated human chromatin. (1990) (132)
- Search for a Prion-Specific Nucleic Acid (2005) (132)
- Genes and pathways downstream of telomerase in melanoma metastasis. (2006) (130)
- A Novel Role of DNA Polymerase η in Modulating Cellular Sensitivity to Chemotherapeutic Agents (2006) (127)
- Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage. (1991) (123)
- Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblasts. (1981) (122)
- Nucleosome structure controls rates of excision repair in DNA of human cells (1977) (117)
- DNA repair with purines and pyrimidines in radiation- and carcinogen-damaged normal and xeroderma pigmentosum human cells. (1973) (117)
- Unique DNA repair properties of a xeroderma pigmentosum revertant (1987) (116)
- Differences in the regulation by poly(ADP-ribose) of repair of DNA damage from alkylating agents and ultraviolet light according to cell type. (1983) (115)
- Biological Damage from Intranuclear Tritium: DNA Strand Breaks and Their Repair (1972) (107)
- 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light. (1982) (107)
- Inhibition of malignant transformation in vitro by inhibitors of poly(ADP-ribose) synthesis. (1984) (107)
- Xeroderma pigmentosum. Clinical and laboratory investigation of its basic defect. (1969) (106)
- Functional relevance of the histone γH2Ax in the response to DNA damaging agents (2011) (105)
- Relationship of neurologic degeneration to genotype in three xeroderma pigmentosum group G patients. (2002) (104)
- Purified scrapie prions resist inactivation by UV irradiation (1987) (101)
- Health Risks Due to Radon in Drinking Water (2000) (101)
- Increased ultraviolet sensitivity and chromosomal instability related to P53 function in the xeroderma pigmentosum variant. (1999) (96)
- The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein. (1997) (94)
- γH2Ax: Biomarker of Damage or Functional Participant in DNA Repair “All that Glitters Is not Gold!” (2011) (94)
- Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes. (2014) (93)
- Repair of alkylation damage in ultraviolet-sensitive (xeroderma pigmentosum) human cells. (1971) (93)
- Postreplication repair: questions of its definition and possible alteration in xeroderma pigmentosum cell strains. (1979) (93)
- Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells. (1972) (89)
- The risk of melanoma in airline pilots and cabin crew: a meta-analysis. (2015) (87)
- Sister chromatid exchange in xeroderma pigmentosum cells that are defective in DNA excision repair or post-replication repair. (1975) (85)
- Solubility and dialysis limits of DNA oligonucleotides. (1972) (82)
- Is Head and Neck Melanoma Different from Trunk and Extremity Melanomas with Respect to Sentinel Lymph Node Status and Clinical Outcome? (2013) (82)
- Evidence for removal at different rates of O-ethyl pyrimidines and ethylphosphotriesters in two human fibroblast cell lines. (1979) (81)
- Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice (2007) (81)
- Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair. (2000) (80)
- Measuring stem cell frequency in epidermis: A quantitative in vivo functional assay for long-term repopulating cells (2003) (78)
- Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia. (1998) (76)
- Correlations between sister chromatid exchange frequencies and replicon sizes. A model for the mechanism of SCE production. (1981) (75)
- Xeroderma pigmentosum variants have a slow recovery of DNA synthesis after irradiation with ultraviolet light. (1979) (75)
- Repair of damaged DNA in the absence of protein synthesis in mammalian cells. (1973) (71)
- Preferential radiosensitization of mouse sarcoma relative to normal skin by chronic intra-arterial infusion of halogenated pyrimidine analogs. (1971) (71)
- Recovery of DNA synthesis after ultraviolet irradiation of xeroderma pigmentosum cells depends on excision repair and is blocked by caffeine. (1979) (70)
- THE RELATIVE BIOLOGICAL IMPORTANCE OF CYCLOBUTANE AND(6–4) PYRIMIDINE‐PYRIMIDONE DIMER PHOTOPRODUCTS IN HUMAN CELLS: EVIDENCE FROM A XERODERMA PIGMENTOSUM REVERTANT * (1988) (69)
- Repair of pyrimidine(6-4)pyrimidone photoproducts in mouse skin. (1990) (69)
- Rescue of Xrcc1 knockout mouse embryo lethality by transgene-complementation. (2003) (68)
- Repair of psoralen-induced cross-links and monoadducts in normal and repair-deficient human fibroblasts. (1985) (67)
- Investigations into the incorporation of [3H] thymidine into DNA in L-strain cells and the formation of a pool of phosphorylated derivaives during pulse labelling. (1965) (66)
- Excision repair of ultraviolet damage in mammalian cells. Evidence for two steps in the excision of pyrimidine dimers. (1978) (65)
- Effect of 3-aminobenzamide on the rate of ligation during repair of alkylated DNA in human fibroblasts. (1983) (65)
- Human DNA polymerase η activity and translocation is regulated by phosphorylation (2008) (65)
- Do inhibitor studies demonstrate a role for poly(ADP-ribose) in DNA repair? (1985) (64)
- Induction of thioguanine- and ouabain-resistant mutants and single-strand breaks in the DNA of Chinese hamster ovary cells by 3H-thymidine. (1977) (64)
- Structure of repaired sites in human DNA synthesized in the presence of inhibitors of DNA polymerases alpha and beta in human fibroblasts. (1983) (64)
- Impaired immune function in patients with xeroderma pigmentosum. (1985) (64)
- Sedimentation of DNA from human fibroblasts irradiated with ultraviolet light: possible detection of excision breaks in normal and repair-deficient xeroderma pigmentosum cells. (1974) (62)
- Ultraviolet radiation inhibits replicon initiation in S phase human cells. (1980) (62)
- Tumour predisposition and cancer syndromes as models to study gene–environment interactions (2020) (61)
- Photoraactivation: a radiation repair mechanism absent from mammalian cells. (1966) (61)
- Absence of specificity in inhibition of DNA repair replication by DNA-binding agents, cocarcinogens, and steroids in human cells. (1975) (61)
- Photocarcinogenesis: an overview. (1981) (60)
- Overexpression of the XPA repair gene increases resistance to ultraviolet radiation in human cells by selective repair of DNA damage. (1995) (60)
- Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage (2014) (58)
- Clinical characteristics, DNA repair, and complementation groups in xeroderma pigmentosum patients from Egypt. (1980) (58)
- Sensitivity of excision repair in normal human, xeroderma pigmentosum variant and Cockayne's syndrome fibroblasts to inhibition by cytosine arabinoside (1981) (55)
- Photoreactivation of thymine dimers in UV-irradiated human cells: unique dependence on culture conditions. (1977) (54)
- Repair replication and degradation of bromouracil-substituted DNA in mammalian cells after irradiation with ultraviolet light. (1968) (54)
- The relationship between the rate of DNA synthesis and its inhibition by ultraviolet light in mammalian cells. (1967) (54)
- DNA polymerase η undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11‐dependent recombination (2001) (51)
- Poly(ADP-ribose) synthesis is involved in the toxic effects of alkylating agents but does not regulate DNA repair. (1985) (51)
- DNA repair in Chinese hamster cells of different sensitivities to ultra-violet light. (1969) (50)
- Phosphorylated H2Ax is not an unambiguous marker for DNA double-strand breaks (2011) (50)
- Metabolism of caffeine to nucleic acid precursors in mammalian cells. (1976) (49)
- Disturbances in DNA precursor metabolism associated with exposure to an inhibitor of poly(ADP-ribose) synthetase. (1986) (49)
- Investigations into the effects of ultraviolet light on the rate of deoxyribonucleic acid synthesis in mammalian cells. (1965) (49)
- Transient conformation changes in chromatin during excision repair of ultraviolet damage to DNA (1981) (48)
- Do we know the cause of xeroderma pigmentosum? (1990) (47)
- Replicon size and excision repair as factors in the inhibition and recovery of DNA synthesis from ultraviolet damage. (1983) (47)
- The role of poly(ADP-ribose) synthesis in toxicity and repair of DNA damage. (1985) (46)
- Nucleotide excision repair "a legacy of creativity". (2001) (46)
- Specificity and completeness of inhibition of DNA repair by novobiocin and aphidicolin. (1982) (45)
- AN INVESTIGATION OF (A) VARIATION IN RATE OF DNA-SYNTHESIS DURING S-PHASE IN MOUSE L-CELLS; (B) EFFECT OF ULTRA-VIOLET RADIATION ON RATE OF DNA-SYNTHESIS. (1964) (44)
- Protective role of vitamin D signaling in skin cancer formation (2013) (44)
- Pol η is required for DNA replication during nucleotide deprivation by hydroxyurea (2007) (44)
- REPAIR REPLICATION IN CHINESE HAMSTER CELLS AFTER DAMAGE FROM ULTRAVIOLET LIGHT * (1970) (43)
- DNA repair characteristics and mutations in the ERCC2 DNA repair and transcription gene in a trichothiodystrophy patient (1997) (42)
- Repair of uv damage to DNA of implantation-stage mouse embryos in vitro (1975) (42)
- Similar defects in DNA repair and replication in the pigmented xerodermoid and the xeroderma pigmentosum variants. (1980) (42)
- Overlapping pathways for repair of damage from ultraviolet light and chemical carcinogens in human fibroblasts. (1979) (41)
- Xeroderma pigmentosum group C in an isolated region of Guatemala. (2007) (41)
- Why Cockayne syndrome patients do not get cancer despite their DNA repair deficiency (2016) (40)
- H 2 AX phosphorylation within the G 1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks (2006) (39)
- DNA damage from incorporated radioisotopes: influence of the 3H location in the cell. (1975) (39)
- Physical and functional interaction between DDB and XPA in nucleotide excision repair (2008) (39)
- The DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomas. (2010) (36)
- Nomenclature of human DNA repair genes. (1994) (36)
- The relationship between the duration of the S phase and the fraction of cells which incorporate 3-H-thymidine during exponential growth. (1965) (36)
- Vitamin D receptor mediates DNA repair and is UV-inducible in intact epidermis but not cultured keratinocytes (2012) (35)
- DNA damage and repair in normal, xeroderma pigmentosum and XP revertant cells analyzed by gel electrophoresis: excision of cyclobutane dimers from the whole genome is not necessary for cell survival. (1989) (34)
- Increased repair replication in human lymphoid cells by inhibition of polyadenosine diphosphoribose synthesis with no increase in patch sizes. (1985) (33)
- DNA-degradation products from mammalian cells irradiated with ultra-violet light. (1969) (33)
- Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H. (2003) (33)
- DNA repair assays as tests for environmental mutagens. A report of the U.S. EPA Gene-Tox Program. (1982) (32)
- Xeroderma pigmentosum variants: influence of temperature on DNA repair. (1973) (32)
- Repair of ultraviolet damage in human cells also exposed to agents that cause strand breaks, crosslinks, monoadducts and alkylations. (1981) (32)
- Rapid diagnosis of sensitivity to ultraviolet light in fibroblasts from dermatologic disorders, with particular reference to xeroderma pigmentosum. (1988) (31)
- The risk of melanoma in pilots and cabin crew: UV measurements in flying airplanes. (2015) (31)
- Histone H2AX phosphorylation in response to changes in chromatin structure induced by altered osmolarity. (2008) (31)
- Comparison of nucleoid and alkaline sucrose gradients in the analysis of inhibitors of DNA repair in human fibroblasts. (1982) (31)
- Replication of chromosomal and episomal DNA in X-ray-damaged human cells: a cis- or trans-acting mechanism? (1990) (31)
- Human diseases with genetically altered DNA repair processes. (1975) (31)
- A single-site mutation in the XPAC gene alters photoproduct recognition. (1993) (31)
- Excision of thymine dimers from specifically incised DNA by extracts of xeroderma pigmentosum cells (1975) (31)
- CYCLOBUTANE DIMERS AND (6‐4)PHOTOPRODUCTS IN HUMAN CELLS ARE MENDED WITH THE SAME PATCH SIZES (1991) (30)
- Perturbations in simian virus 40 DNA synthesis by ultraviolet light. (1978) (30)
- Enhanced ligation of repair sites under conditions of inhibition of poly(ADP-ribose) synthesis by 3-aminobenzamide. (1986) (30)
- Trichothiodystrophy: clinical spectrum, central nervous system imaging, and biochemical characterization of two siblings. (1994) (30)
- BPTF transduces MITF-driven prosurvival signals in melanoma cells (2016) (30)
- DNA replication arrest in XP variant cells after UV exposure is diverted into an Mre11-dependent recombination pathway by the kinase inhibitor wortmannin. (2002) (30)
- Conformation of DNA in alkaline sucrose: the subunit hypothesis in mammalian cells. (1974) (30)
- Polymerase η and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation (2002) (30)
- Xeroderma pigmentosum patients from Egypt: II. Preliminary correlations of epidemiology, clinical symptoms and molecular biology. (1981) (30)
- Unique cross-link and monoadduct repair characteristics of a xeroderma pigmentosum revertant cell line. (1987) (30)
- Xeroderma pigmentosum variant with multisystem involvement. (1992) (29)
- Absence of DNA repair replication after chemical mutagen damage in Vicia faba. (1973) (29)
- Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes. (1993) (29)
- Xeroderma pigmentosum variants. (1981) (28)
- Completion of excision repair patches in human cell preparations: identification of a probable mode of excision and resynthesis. (1984) (28)
- Distribution of Chromatids at Mitosis (1967) (27)
- Replication of nuclear and mitochondrial DNA in X-ray-damaged cells: evidence for a nuclear-specific mechanism that down-regulates replication. (1992) (27)
- Inhibition by hyperthermia of repair synthesis and chromatin reassembly of ultraviolet-induced damage to DNA. (1984) (27)
- Alternative recombination pathways in UV-irradiated XP variant cells (2005) (27)
- Stopping DNA Replication in Its Tracks (1999) (27)
- Photosensitivity syndrome brings to light a new transcription-coupled DNA repair cofactor (2012) (27)
- Xeroderma pigmentosum exhibiting neurological disorders and systemic lupus erythematosus (1980) (26)
- Caffeine toxicity is inversely related to DNA repair in simian virus 40-transformed xeroderma pigmentosum cells irradiated with ultraviolet light. (1989) (26)
- 3-Aminobenzamide can act as a cocarcinogen for ultraviolet light-induced carcinogenesis in mouse skin. (1992) (26)
- XERODERMA PIGMENTOSUM: GENETIC AND ENVIRONMENTAL INFLUENCES IN SKIN CARCINOGENESIS (1978) (26)
- Prenatal diagnosis of xeroderma pigmentosum and cockayne syndrome (1994) (26)
- Repair of damaged DNA by extracts from a xeroderma pigmentosum complementation group A revertant and expression of a protein absent in its parental cell line. (1992) (25)
- 3-Aminobenzamide, an inhibitor of poly(ADP-ribose) polymerase, is a stimulator, not an inhibitor, of DNA repair. (1987) (25)
- Morphological transformation of 10T1/2 mouse embryo cells can be initiated by DNA double‐strand breaks alone (1991) (25)
- Clinical syndromes associated with DNA repair deficiency and enhanced sun sensitivity. (1993) (25)
- Excision repair in xeroderma pigmentosum group C but not group D is clustered in a small fraction of the total genome. (1986) (24)
- Quiescent human lymphocytes do not contain DNA strand breaks detectable by alkaline elution. (1989) (24)
- Restriction enzyme cleavage of ultraviolet-damaged simian virus 40 and pBR322 DNA. (1983) (23)
- DNA repair in human xeroderma pigmentosum group C cells involves a different distribution of damaged sites in confluent and growing cells. (1986) (23)
- Ultraviolet Irradiation Produces Novel Endonuclease Ill‐Sensitive Cytosine Photoproducts at Dipyrimidine Sites (1997) (23)
- Differential toxicity of 3-aminobenzamide to wild-type and 6-thioguanine-resistant Chinese hamster cells by interference with pathways of purine biosynthesis. (1984) (23)
- Conceptual developments in the causes of Cockayne syndrome (2013) (23)
- The effect of delay time between primary melanoma biopsy and sentinel lymph node dissection on sentinel node status, recurrence, and survival (2012) (23)
- Clinical implications of the basic defects in Cockayne syndrome and xeroderma pigmentosum and the DNA lesions responsible for cancer, neurodegeneration and aging (2008) (23)
- UV-induced reversion of a temperature-sensitive late mutant of simian virus 40 to a wild-type phenotype (1975) (22)
- Absence of interaction between X-rays and UV light in inducing ouabain- and thioguanine-resistant mutants in Chinese hamster cells. (1978) (22)
- Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome (2012) (21)
- Direct visualization of the sites of DNA methylation in human, and mosquito chromosomes (2004) (21)
- Replicon sizes in non-transformed and SV 40-transformed cells, as estimated by a bromodeoxyuridine photolysis method. (1979) (21)
- Induction of DNA-DNA cross-link formation in human cells by various psoralen derivatives. (1985) (21)
- DNA Replication in the Face of (In)surmountable Odds (2003) (20)
- Repair and replication of DNA in hereditary (bilateral) retinoblastoma cells after X-irradiation. (1982) (20)
- Cockayne syndrome exhibits dysregulation of p21 and other gene products that may be independent of transcription-coupled repair (2007) (20)
- Inhibition of excision-repair of ultraviolet damage in human cells by exposure to methyl methanesulfonate. (1981) (20)
- Xeroderma pigmentosum variant cells are resistant to immortalization. (1995) (20)
- Repair of psoralen adducts in human DNA: differences among xeroderma pigmentosum complementation groups. (1984) (20)
- Enzyme digestion of intermediates of excision repair in human cells irradiated with ultraviolet light. (1982) (19)
- Prognostic Impact of PHIP Copy Number in Melanoma: Linkage to Ulceration (2013) (19)
- Restriction enzyme cleavage of ultraviolet-damaged DNA. (1982) (19)
- Quantification of XPA gene expression levels in human and mouse cell lines by competitive RT-PCR. (1997) (19)
- Relationship of ultraviolet light-induced DNA-protein cross-linkage to chromatin structure. (1985) (19)
- Radon-induced deletions in human cells: role of nonhomologous strand rejoining. (1992) (19)
- PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex (2020) (19)
- DNA repair on the brain (2001) (18)
- Xeroderma Pigmentosum—Progress and Regress (1973) (18)
- Sister chromatid exchanges in cells defective in mismatch, post-replication and excision repair. (1995) (17)
- Elevated DNA excision repair capacity in the extraembryonic mesoderm of the midgestation mouse embryo. (1996) (17)
- Exposure chamber for quantitative ultraviolet photobiology. (1969) (17)
- The action of ultraviolet light on the patterns of banding induced by restriction endonucleases in human chromosomes (2004) (17)
- Repair-deficient xeroderma pigmentosum cells made UV light resistant by fusion with X-ray-inactivated Chinese hamster cells (1986) (17)
- EFFICIENCY OF REPAIR OF PYRIMIDINE DIMERS AND PSORALEN MONOADDUCTS IN NORMAL AND XERODERMA PIGMENTOSUM HUMAN CELLS (1984) (17)
- Antagonistic action of a tumor promoter and a poly(adenosine diphosphoribose) synthesis inhibitor in radiation-induced transformation in vitro. (1986) (17)
- Absence of skin cancer in the DNA repair-deficient disease Cockayne Syndrome (CS): A survey study. (2016) (17)
- Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation. (2002) (16)
- DNA repair deficiencies and cellular senescence are unrelated in xeroderma pigmentosum cell lines (1984) (16)
- 3 – METHODS FOR STUDYING EXCISION REPAIR OF EUKARYOTIC DNA DAMAGED BY PHYSICAL AND CHEMICAL MUTAGENS (1984) (16)
- HOECHST 33258 DYE GENERATES DNA‐PROTEIN CROSS‐LINKS DURING ULTRAVIOLET LIGHT‐INDUCED PHOTOLYSIS OF BROMODEOXYURIDINE IN REPLICATED AND REPAIRED DNA (1986) (16)
- Modification of the Comet assay for the detection of DNA strand breaks in extremely small tissue samples. (1999) (16)
- Methylating and ethylating carcinogens have different requirements for poly(ADP-ribose) synthesis during malignant transformation. (1984) (16)
- Repair replication and sister chromatid exchanges as indicators of excisable and nonexcisable damage in human (xeroderma pigmentosum) cells. (1977) (15)
- Inhibition of DNA replication by hydroxyurea and caffeine in an ultraviolet-irradiated human fibroblast cell line. (1981) (15)
- Ultraviolet Radiation Carcinogenesis (2003) (15)
- Classics in DNA RepairPhotoreactivation (2003) (15)
- Plaque Formation with Simian Virus 40: Enhancement by Dimethyl Sulfoxide (1974) (14)
- Inhibition of X-ray- and ultraviolet light-induced transformation in vitro by modifiers of poly(ADP-ribose) synthesis. (1984) (14)
- Some protease inhibitors are also inhibitors of poly(ADP-ribose) polymerase. (1986) (14)
- Novobiocin-mediated inhibition of polymerization and ligation of DNA in vitro. (1984) (14)
- Combined Immunodeficiency Associated with Xeroderma Pigmentosum (1990) (14)
- Normal reconstruction of DNA supercoiling and chromatin structure in cockayne syndrome cells during repair of damage from ultraviolet light. (1982) (14)
- Protease inhibitors neither damage DNA nor interfere with DNA repair or replication in human cells. (1981) (14)
- Poly(ADP-ribose): spectator or participant in excision repair of DNA damage. (1983) (14)
- Induction and repair of (6-4) photoproducts in normal human and xeroderma pigmentosum variant cells during the cell cycle. (1995) (14)
- Nucleotide Excision Repair and Human Disease (2004) (14)
- Rapid complementation method for classifying excision repair-defective xeroderma pigmentosum cell strains (1982) (13)
- PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer (2018) (13)
- Inactivation of ultraviolet repair in normal and xeroderma pigmentosum cells by methyl methanesulfonate. (1982) (13)
- DNA repair in man: Regulation by a multigene family and association with human disease (1987) (13)
- Letter: Biological damage from intranuclear carbon-14 decays: DNA single-strand breaks and repair in mammalian cells. (1974) (12)
- Is the non-sentinel lymph node compartment the next site for melanoma progression from the sentinel lymph node compartment in the regional nodal basin? (2017) (12)
- Removal of T4 endonuclease V-sensitive sites from SV40 DNA after exposure to ultraviolet light. (1979) (12)
- A deletion and an insertion in the alleles for the xeroderma pigmentosum (XPA) DNA-binding protein in mildly affected patients. (1995) (12)
- INHIBITION OF DNA SYNTHESIS BY PSORALEN‐INDUCED LESIONS IN XERODERMA PIGMENTOSUM AND FANCONI'S ANEMIA FIBROBLASTS (1985) (12)
- Chromatin dynamics. Fast and slow modes of nucleosome movement revealed through psoralen binding and repair. (1985) (12)
- p53 suppression overwhelms DNA polymerase eta deficiency in determining the cellular UV DNA damage response. (2007) (12)
- Splitting hairs--discovery of a new DNA repair and transcription factor for the human disease trichothiodystrophy. (2005) (12)
- Sensitization of mouse L cells to ultraviolet light by low amounts of bromodeoxyuridine. (1982) (12)
- DNA ligation and changes in chromatin structure associated with repair patches under conditions of inhibition of poly(ADP-ribose) synthesis. (1986) (11)
- Sunlight avoidance and cancer prevention in xeroderma pigmentosum. (1994) (11)
- Cells have long experience of dealing with UVC light (2006) (11)
- Historical aspects of xeroderma pigmentosum and nucleotide excision repair. (2008) (11)
- DNA repair and replication in xeroderma pigmentosum and related disorders. (1986) (11)
- Nucleotide excision repair: variations associated with cancer development and speciation. (1995) (11)
- Both cross-links and monoadducts induced in DNA by psoralens can lead to sister chromatid exchange formation. (1991) (11)
- Is There a Role for ADP-Ribosylation in DNA Repair? (1985) (10)
- DNA damage, repair systems and human hypersensitive diseases. (1980) (10)
- Xeroderma pigmentosum family support group: Helping families and promoting clinical initiatives. (2011) (10)
- Xeroderma pigmentosum: the first of the cellular caretakers. (2001) (10)
- Transcription coupled repair deficiency protects against human mutagenesis and carcinogenesis: Personal Reflections on the 50th anniversary of the discovery of xeroderma pigmentosum. (2017) (10)
- DNA excision repair in permeable human fibroblasts. (1983) (10)
- An autosomal dominant inheritance for multiple sunlight-induced malignancy in a patient without abnormalities in DNA repair or replication. Repository identification No. GM2881. (1981) (10)
- “If the shoe fits”: clues on structural recognition of DNA damage (1995) (10)
- Inhibition of DNA Synthesis by Ultra-Violet Light Under Controlled Temperature (1966) (10)
- Repair replication in replicating and non-replicating DNA after irradiation with UV light. (1978) (10)
- Reappraisal of the prognostic significance of mitotic rate supports its reincorporation into the melanoma staging system (2020) (9)
- Adenovirus mediated transduction of the human DNA polymerase eta cDNA. (2006) (9)
- Ultraviolet photobiology: its early roots and insights into DNA repair. (2002) (9)
- Transcription-related human disorders. (1995) (9)
- The pattern of restriction enzyme-induced banding in the chromosomes of chimpanzee, gorilla, and orangutan and its evolutionary significance (2005) (9)
- Decline in mutation frequency in temperature-sensitive SV40 viruses before viral DNA synthesis. (1977) (9)
- CELL SURVIVAL, EXCISION REPAIR AND DNA REPLICATION IN EUKARYOTIC CELLS (1978) (9)
- Halogen lamp phototoxicity. (1996) (9)
- Chromatid exchanges may be induced by damage in sites of transcriptional activity. (1996) (8)
- Hair Today, Gone Tomorrow: Transgenic Mice with Human Repair Deficient Hair Disease (1998) (8)
- Repair of DNA damage in shuttle vectors, virus, and chromosomal DNAs may depend on their biological imprinting--a 'Pygmalion' effect. (1989) (8)
- Polymerase h deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair (2000) (8)
- Profile of Tomas Lindahl, Paul Modrich, and Aziz Sancar, 2015 Nobel Laureates in Chemistry (2015) (8)
- Mutation frequencies from X-rays, ultraviolet light, and methyl methanesulfonate in Chinese hamster ovary cells incubated with 3-aminobenzamide. (1986) (8)
- Relative importance of incision and polymerase activities in determining the distribution of damaged sites that are mended in xeroderma pigmentosum group C cells. (1987) (7)
- Critical biochemical and regulatory events in malignant transformation in vitro. (1983) (7)
- Enhanced excision of O6-alkylguanine in rat liver by pretreatment with acetylaminofluorene (1980) (7)
- Evaluation of short-term tests for carcinogens: A report of the international programme on chemical safety's collaborative study on in vivo assays. (1989) (7)
- Pigmented xerodermoid and XP-variants (2004) (7)
- DNA repair in man. (1989) (7)
- Mechanisms by which Human Cells Bypass Damaged Bases during DNA Replication after Ultraviolet Irradiation (2002) (7)
- Formation and repair of psoralen-DNA adducts and pyrimidine dimers in human DNA and chromatin. (1985) (7)
- Cockayne syndrome complementation group B associated with xeroderma pigmentosum phenotype (1996) (7)
- Diagnosis of Xeroderma Pigmentosum and Related DNA Repair-Deficient Cutaneous Diseases. (2008) (7)
- Climate’s cascading effects on disease, predation, and hatching success in Anaxyrus canorus, the threatened Yosemite toad (2020) (6)
- REPAIR OF MAMMALIAN CELL DNA: EFFECTS OF DRUGS AND MUTATIONS. (1969) (6)
- Differences in the stimulation of repair replication by 3-aminobenzamide in lymphoblastoid cells damaged by methylmethanesulfonate or ultraviolet light. (1987) (6)
- Value of measurements of DNA repair levels in predicting carcinogenic potential of chemicals (1976) (6)
- Evaluation of homology between cloned Escherichia coli and yeast DNA photolyase genes and higher eukaryotic genomes. (1986) (6)
- Selective Sentinel Lymph Node Dissection in Lower Extremity Melanoma (2016) (6)
- Rough skin, brittle hair, and photosensitivity: a mild phenotypic variant of trichothiodystrophy (2000) (5)
- Voriconazole does not Potentiate Photo Damage from UVB Exposure (2013) (5)
- Timing chromosomal abnormalities using mutation data (2011) (5)
- Cambridge Laboratory of Molecular Biology (2003) (5)
- Effect of Physiological Saline on Synthesis of Deoxyribonucleic Acid and Ribonucleic Acid in Mammalian Cells (1965) (5)
- Richard B. Setlow, a commentary on seminal contributions and scientific controversies (2001) (4)
- Evidence for a defect in thymine dimer excision in extracts of Xeroderma pigmentosum cells (1977) (4)
- Single-strand breaks in DNA of hamster and human cells exposed to methyl methanesulfonate and ultraviolet light. (1985) (4)
- EXCISION OF CYCLOBUTANE DIMERS IN GENOMIC AND EPISOMAL DNA IN HUMAN CELLS (1994) (4)
- Xeroderma pigmentosum in Egypt. III. ABO blood grouping in 22 affected families (1984) (4)
- Nuclear Receptor Coactivator NCOA3 Regulates UV Radiation–Induced DNA Damage and Melanoma Susceptibility (2021) (4)
- Sensitivity of mitomycin C and nitrogen mustard crosslinks to extreme alkaline conditions. (1984) (4)
- Defective repair replication of DNA in xeroderma pigmentosum. 1968. (2004) (4)
- Non-rejoining DNA breaks and cell inactivation (reply) (1978) (4)
- Similar distributions of repaired sites in chromatin of normal and xeroderma pigmentosum variant cells damaged by ultraviolet light. (1979) (4)
- Excision repair: our current knowledge based on human (xeroderma pigmentosum) and cattle cells. (1972) (4)
- Reparir of UV damage to DNA of implantation-stage mouse embryos in vitro. (1975) (3)
- Chemical Characterization and Removal of C-14 from Irradiated Graphite-12010 (2012) (3)
- Chemical Characterization and Removal of Carbon-14 from Irradiated Graphite II - 13023 (2013) (3)
- Excision repair--its bacterial beginnings. (2003) (3)
- Stimulation of repair replication by 3-aminobenzamide in human fibroblasts with ligase I deficiency. (1996) (3)
- Excision repair in mammalian cells and the current status of xeroderma pigmentosum. [uv radiation] (1977) (3)
- Membrane initiation of DNA synthesis (1977) (3)
- A bacterial plasmid DNA miniprep using microwave lysis. (1994) (3)
- Repair deficient and hypersensitive diseases of man (1979) (2)
- A Role for Poly(ADP-Ribose) in Radiogenic and Chemically-Induced Malignant Transformation and Mutagenesis (1985) (2)
- How many human genetic disorders affect cellular radiosensitivity? (1989) (2)
- Excision repair--the first steps into mammalian cells. 1968. (2004) (2)
- Excision repair in xeroderma pigmentosum group C cells is regulated differently in transformed cells and primary fibroblasts. (1988) (2)
- The Biology of Xeroderma Pigmentosum (2006) (2)
- Mending human genes: a job for a lifetime. (2005) (2)
- HAEMATOLOGICAL CONSEQUENCES OF RADIOISOTOPE INCORPORATION WITH PARTICULAR REFERENCE TO TRITIUM, PHOSPHORUS, AND STRONTIUM. (1971) (2)
- Chromosome damage and repair (1983) (2)
- CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress * (2021) (2)
- Transmutation and decay of incorporated radioisotopes. (1968) (2)
- Ocular squamous cell carcinoma (cancer eye) in Hereford cattle: radiation repair processes and a comparison of cultured cells with xeroderma pigmentosum in man. (1972) (2)
- Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma (2022) (1)
- Enzyme defect in xeroderma pigmentosum. (1970) (1)
- IN MEMORIAM (2009) (1)
- I never expected to have such an interesting career, meet so many stimulating people and see so many exotic places. (2011) (1)
- CERKL is Upregulated in Cutaneous Squamous Cell Carcinoma and Maintains Cellular Sphingolipids and Resistance to Oxidative Stress. (2020) (1)
- Tritiated Thymidine: Xeroderma Pigmentosum and DNA Repair (2014) (1)
- Interactions of Hydrogen Isotopes and Oxides with Metal Tubes (2008) (1)
- The UVSSA protein is part of a genome integrity homeostasis network with links to transcription-coupled DNA repair and ATM signaling (2022) (1)
- Induction of thioguanine- and ouabain-resistant mutants and single-strand breaks in the DNA of Chinese hamster ovary cells by /sup 3/H-thymidine. [X and uv radiation] (1977) (1)
- Genome sequence and splice site analysis of low-fidelity DNA polymerases H and I involved in replication of damaged DNA. (2003) (1)
- Editorial (2016) (1)
- Xeroderma Pigmentosum and the DNA Damage Response to Ultraviolet Light (2017) (1)
- Variations in Sensitivity and DNA Repair in Human Cells Exposed to Genotoxic Agents (1984) (1)
- The Cytogenetic Effects of an Inhibition of Poly(ADP-Ribose) Polymerase (1989) (1)
- Metabolic effects of poly (ADP-ribose) inhibitors. (1985) (1)
- Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting. (2020) (1)
- Tumour predisposition and cancer syndromes as models to study gene–environment interactions (2020) (0)
- Genetic Factors in Skin Carcinogenesis (2003) (0)
- Rick Jostes and the BEIR VII Report: Response to Maurice Tubiana and Ludwig E. Feinendegen (2010) (0)
- DNA repair and cell survival in human cells of normal and xeroderma pigmentosum genotype (1973) (0)
- Book Review:Molecular Radiobiology. N. B. Strazhevskaya, A. Mercado, P. Harry (1976) (0)
- Mechanisms of DNA repair and the structure of repaired sites in the presence of polymerase inhibitors. (1984) (0)
- HRAD30A, a Gene Encoding a Class Y Low-Fidelity Dna Polymerase Has a Low Complexity Region in Intron I Associated with Tissue-Specific Alternative Splicing (2002) (0)
- TISSUE CULTURE EXPERIMENTS IN HEREDITARY SKIN CANCER: DNA REPAIR SYNTHESIS. (1970) (0)
- Inhibition of radiogenic and chemical oncogenesis by inhibitors of poly (adp-ribose). Abstr. (1983) (0)
- The Gordon conference on mammalian DNA repair (1993) (0)
- Beardedness in Advertising (2011) (0)
- Photobiology of Photocarcinogenesis (2006) (0)
- PEG fusion 1 UV selection Primary Hybrids X-ray " ' PEG fusion UV selection Secondary Hybrids X-ray 2 PEG fusion 1 UV selection Tertiary Hybrids (0)
- Microbial Community Function and Biomarker Discovery in the Human Microbiome (2011) (0)
- REPAIR OF UV IRRADIATION DAMAGE IN SIMIAN VIRUS 40 (1978) (0)
- Retinoblastoma: Experimental Studies (1983) (0)
- DNA repair processes in human cells (1978) (0)
- DNA Replication Arrest and P53-Dependent and P53-Independent Cell Death Pathways in Xeroderma Pigmentosum Variant Cells (2001) (0)
- Biophysical and Physiological Effects of Solar Radiation on Human Skin, P.U. Giacomoni (Ed.). Royal Society of Chemistry, Cambridge, UK (2007), ISBN-10: 08540289X; ISBN-13: 978-0854042890 (2008) (0)
- Proximity of repair patches to persistent pyrimidine dimers in DNA of normal human and xeroderma pigmentosum cells. (1988) (0)
- Selective Use of Data (1980) (0)
- INVITED EDITORIAL Transcription-Related Human Disorders (2007) (0)
- Abstract 17: Selective Sentinel Lymph Node Dissection in Lower Extremity Melanoma (2014) (0)
- Bo we kmow the caose of xeroderma pigmemitosmim (1990) (0)
- Editorial help (2004) (0)
- DNA damage and repair from 3H and 14C incorporated in macromolecules. (1974) (0)
- Beatrice A. Singer: In Memoriam (1923–2005) (2006) (0)
- Multiple Roles for Poly(ADP-Ribose) Synthesis in Repair of DNA Damage and Malignant Transformation (1989) (0)
- The XPC-ATM-JNK-γH2AX pathway mediates UV-induced apoptosis in response to DNA replication arrest. (2008) (0)
- Genetics of human sensitivity to ultraviolet radiation (1994) (0)
- XerodermaPigmentosum andCockayneSyndrome: Overlapping Clinical andBiochemical Phenotypes (1992) (0)
- Timing chromosomal abnormalities using mutation data (2011) (0)
- Complementation of xeroderma pigmentosum variant cells by a recombinant adenovirus carrying the polymerase ETA cDNA (2004) (0)
- Advances in Brief Recapitulation of the Cellular Xeroderma Pigmentosum-Variant Phenotypes Using Short Interfering RNA for DNA Polymerase 1 (2003) (0)
- Genetic testing. (1994) (0)
- MECHANISMS OF RADIATION DAMAGE AND REPAIR IN HUMAN AND OTHER MAMMALIAN CELLS. (1972) (0)
- Sheldon Wolff (1929–2008) (2008) (0)
- Tritiated uracil, tritiated thymidine, and bromodeoxyuridine induced mutations in eucaryotic cells. [Saccharomyces cerevisiae, gamma radiation] (1979) (0)
- Next-generation sequencing identifies Notch receptors as integral tumor suppressors in cutaneous and lung squamous cell carcinomas (2012) (0)
- Letter from James E. Cleaver to Joshua Lederberg (1968) (0)
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