Jeffrey Ern Saffitz
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- Doctorate Medicine Harvard University
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(Suggest an Edit or Addition)Jeffrey Ern Saffitz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria. (2010) (1585)
- Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Proposed Modification of the Task Force Criteria (2010) (1583)
- Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. (2000) (1242)
- PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis (2005) (751)
- A novel mouse model of lipotoxic cardiomyopathy. (2001) (751)
- Dephosphorylation and Intracellular Redistribution of Ventricular Connexin43 During Electrical Uncoupling Induced by Ischemia (2000) (509)
- Evidence for Cardiomyocyte Repopulation by Extracardiac Progenitors in Transplanted Human Hearts (2002) (461)
- Rapid turnover of connexin43 in the adult rat heart. (1998) (457)
- A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy. (2008) (440)
- A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. (1998) (431)
- 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy. (2019) (393)
- Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy (2012) (374)
- Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor &ggr; Coactivator-1&agr; Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developmental Stage-Dependent Manner (2004) (373)
- The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy (2001) (356)
- Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease). (2004) (329)
- Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. (1997) (323)
- Desmosomal Dysfunction due to Mutations in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (2006) (308)
- Tissue-specific determinants of anisotropic conduction velocity in canine atrial and ventricular myocardium. (1994) (305)
- Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy. (2010) (302)
- 2011 consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. (2012) (299)
- Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. (1995) (295)
- Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. (2000) (291)
- Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated. (1995) (289)
- Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. (2004) (277)
- Reentrant and Focal Mechanisms Underlying Ventricular Tachycardia in the Human Heart (1992) (275)
- Distribution and Three‐Dimensional Structure of Intercellular Junctions in Canine Myocardium (1989) (273)
- Remodeling of ventricular conduction pathways in healed canine infarct border zones. (1991) (266)
- Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: evidence for chamber-specific molecular determinants of conduction. (1998) (255)
- Interobserver variability in the pathologic interpretation of endomyocardial biopsy results. (1987) (250)
- Cardiac myocytes express multiple gap junction proteins. (1992) (241)
- 3D MRI-Based Multicomponent FSI Models for Atherosclerotic Plaques (2004) (239)
- A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy. (2007) (235)
- Pulsatile Stretch Remodels Cell-to-Cell Communication in Cultured Myocytes (2000) (225)
- Gap Junction Protein Phenotypes of the Human Heart and Conduction System (1995) (218)
- Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy (2014) (215)
- Structural and molecular pathology of the heart in Carvajal syndrome. (2004) (215)
- The role of myocardial gap junctions in electrical conduction and arrhythmogenesis. (2001) (204)
- Expression of multiple connexins in cultured neonatal rat ventricular myocytes. (1995) (195)
- Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. (1994) (190)
- Renal dysfunction and intravascular coagulation with aprotinin and hypothermic circulatory arrest. (1993) (186)
- Intramural Reentry as a Mechanism of Ventricular Tachycardia during Evolving Canine Myocardial Infarction (1985) (185)
- Functional and structural assessment of intercellular communication. Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes. (1996) (179)
- Murine γ-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-γ responsiveness: A new model for virus-induced vascular disease (1997) (170)
- Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation. (1989) (170)
- Alpha adrenergic-mediated accumulation of calcium in reperfused myocardium. (1983) (168)
- Extracardiac Progenitor Cells Repopulate Most Major Cell Types in the Transplanted Human Heart (2005) (168)
- Connexin expression and turnover : implications for cardiac excitability. (2000) (163)
- High resolution optical mapping reveals conduction slowing in connexin43 deficient mice. (2001) (158)
- Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study (2012) (158)
- Transmyocardial laser treatment denervates canine myocardium. (1997) (154)
- Anisotropic activation spread in heart cell monolayers assessed by high-resolution optical mapping. Role of tissue discontinuities. (1996) (154)
- Severe cardiac phenotype with right ventricular predominance in a large cohort of patients with a single missense mutation in the DES gene. (2009) (148)
- Altered Desmosomal Proteins in Granulomatous Myocarditis and Potential Pathogenic Links to Arrhythmogenic Right Ventricular Cardiomyopathy (2011) (147)
- c-Jun N-Terminal Kinase Activation Mediates Downregulation of Connexin43 in Cardiomyocytes (2002) (146)
- Impulse Propagation in Synthetic Strands of Neonatal Cardiac Myocytes With Genetically Reduced Levels of Connexin43 (2003) (143)
- Mechanisms of Delayed Electrical Uncoupling Induced by Ischemic Preconditioning (2003) (142)
- Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. (1997) (134)
- Mechanisms of remodeling of gap junction distributions and the development of anatomic substrates of arrhythmias. (1999) (133)
- Multiple connexins colocalize in canine ventricular myocyte gap junctions. (1993) (132)
- Quantitative ultrasonic characterization of the nature of atherosclerotic plaques in human aorta. (1987) (131)
- Distinct patterns of connexin expression in canine Purkinje fibers and ventricular muscle. (1993) (129)
- Molecular mechanisms of arrhythmogenic cardiomyopathy (2019) (129)
- Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. (2013) (128)
- Quantifying effects of plaque structure and material properties on stress distributions in human atherosclerotic plaques using 3D FSI models. (2005) (128)
- Differential expression of gap junction proteins in the canine sinus node. (1998) (127)
- The rapid and reversible activation of a calcium-independent plasmalogen-selective phospholipase A2 during myocardial ischemia. (1991) (127)
- Local Maximal Stress Hypothesis and Computational Plaque Vulnerability Index for Atherosclerotic Plaque Assessment (2005) (126)
- Autocrine Regulation of Myocyte Cx43 Expression by VEGF (2002) (125)
- Filamin C Truncation Mutations Are Associated With Arrhythmogenic Dilated Cardiomyopathy and Changes in the Cell–Cell Adhesion Structures (2018) (123)
- Mechanoelectrical Feedback as Novel Mechanism of Cardiac Electrical Remodeling (2007) (120)
- Intraoperative ultrasonic imaging of the ascending aorta. (1989) (120)
- The Molecular Basis of Anisotropy: Role of Gap Junctions (1995) (117)
- Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy. (2016) (113)
- 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy: Executive summary. (2019) (113)
- Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice. (2003) (111)
- Effects of diminished expression of connexin43 on gap junction number and size in ventricular myocardium. (2000) (110)
- Targeted Activation of c-Jun N-terminal Kinase in Vivo Induces Restrictive Cardiomyopathy and Conduction Defects*[boxs] (2004) (110)
- Electrical Propagation in Synthetic Ventricular Myocyte Strands From Germline Connexin43 Knockout Mice (2004) (108)
- The Dependence of Electrophysiological Derangements on Accumulation of Endogenous Long‐Chain Acyl Camitine in Hypoxic Neonatal Rat Myocytes (1986) (105)
- Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes. (1998) (105)
- Echocardiographic evaluation of ventricular remodeling in a mouse model of myocardial infarction. (2002) (103)
- Relative Contributions of Connexins 40 and 43 to Atrial Impulse Propagation in Synthetic Strands of Neonatal and Fetal Murine Cardiomyocytes (2006) (102)
- Arrhythmogenic Phenotype in Dilated Cardiomyopathy: Natural History and Predictors of Life‐Threatening Arrhythmias (2015) (102)
- Effects of angiotensin II on expression of the gap junction channel protein connexin43 in neonatal rat ventricular myocytes. (1998) (102)
- Distinct Pathways Regulate Expression of Cardiac Electrical and Mechanical Junction Proteins in Response to Stretch (2005) (101)
- Desmin mutations as a cause of right ventricular heart failure affect the intercalated disks. (2010) (101)
- Dependence of Electrical Coupling on Mechanical Coupling in Cardiac Myocytes: Insights Gained from Cardiomyopathies Caused by Defects in Cell‐Cell Connections (2005) (96)
- Up‐Regulation of Connexin45 in Heart Failure (2003) (92)
- Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition. (2003) (91)
- Applicability of ultrasonic tissue characterization for longitudinal assessment and differentiation of calcification and fibrosis in cardiomyopathy. (1984) (91)
- Mortality and morbidity in pre-sensitized pediatric heart transplant recipients with a positive donor crossmatch utilizing peri-operative plasmapheresis and cytolytic therapy. (2007) (91)
- Synthetic Strands of Neonatal Mouse Cardiac Myocytes: Structural and Electrophysiological Properties (2000) (90)
- Inhibition of gap junctional conductance by long-chain acylcarnitines and their preferential accumulation in junctional sarcolemma during hypoxia. (1993) (85)
- Prevention of reoccluding platelet-rich thrombi in canine femoral arteries with a novel peptide antagonist of platelet glycoprotein IIb/IIIa receptors. (1989) (82)
- Reversible myocardial ischemic injury is not associated with increased creatine kinase activity in plasma. (1997) (82)
- Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy. (2019) (82)
- Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy. (2007) (81)
- Arrhythmogenic cardiomyopathy and abnormalities of cell-to-cell coupling. (2009) (77)
- Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart. (2004) (76)
- β‐Adrenergic Receptor Distribution Among Muscle Fiber Types and Resistance Arterioles of Winte, Red, and Intermediate Skeletal Muscle (1989) (76)
- Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report (2019) (73)
- Delineation of the distribution of beta-adrenergic receptor subtypes in canine myocardium. (1988) (73)
- The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo. (1995) (73)
- Connexin43 Mutation Causes Heterogeneous Gap Junction Loss and Sudden Infant Death (2012) (73)
- Avoidance of embolic complications by ultrasonic characterization of the ascending aorta. (1989) (72)
- Effects of Reperfusion on Ischemic Right Ventricular Dysfunction: Disparate Mechanisms of Benefit Related to Duration of Ischemia (1994) (69)
- Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45. (1994) (66)
- A call to action: training pathology residents in genomics and personalized medicine. (2010) (65)
- Incorporation of Radiolabeled Lysophosphatidyl Choline into Canine Purkinje Fibers and Ventricular Muscle: Electrophysiological, Biochemical, and Autoradiographic Correlations (1982) (64)
- A national agenda for the future of pathology in personalized medicine: report of the proceedings of a meeting at the Banbury Conference Center on genome-era pathology, precision diagnostics, and preemptive care: a stakeholder summit. (2011) (61)
- Quantitative Analysis of Intercellular Connections by Immunohistochemistry of the Cardiac Gap Junction Protein Connexin43 (1989) (61)
- Cardiac dysfunction associated with a nucleotide polymerase inhibitor for treatment of hepatitis C (2015) (61)
- Heterogeneous Transmural Distribution of Beta‐Adrenergic Receptor Subtpes in Failing Human Hearts (1993) (61)
- Mechanisms of impaired exercise capacity in short duration experimental hyperthyroidism. (1991) (60)
- Distribution of beta-adrenergic receptors in failing human myocardium. Implications for mechanisms of down-regulation. (1989) (60)
- Biallelic Truncating Mutations in ALPK3 Cause Severe Pediatric Cardiomyopathy. (2016) (59)
- Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress* (2011) (59)
- Matrix Protein–Specific Regulation of Cx43 Expression in Cardiac Myocytes Subjected to Mechanical Load (2005) (58)
- Uptake and subcellular distribution of [3H]arachidonic acid in murine fibrosarcoma cells measured by electron microscope autoradiography (1985) (56)
- Relative densities of muscarinic cholinergic and beta-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. (1995) (56)
- Transmural heterogeneity of norepinephrine uptake in failing human hearts. (1994) (56)
- Elevated donor cardiac troponin I. A marker of acute graft failure in infant heart recipients. (1994) (55)
- Transmural Distribution of Connexins in Rodent Hearts (2004) (54)
- Dramatic Accumulation of Triglycerides and Precipitation of Cardiac Hemodynamic Dysfunction during Brief Caloric Restriction in Transgenic Myocardium Expressing Human Calcium-independent Phospholipase A2γ* (2007) (54)
- Electrical Coupling and Propagation in Engineered Ventricular Myocardium With Heterogeneous Expression of Connexin43 (2012) (54)
- Fibronectin in rat heart: a link between cardiac myocytes and collagen. (1984) (52)
- Quantitative autoradiographic delineation of the distribution of beta-adrenergic receptors in canine and feline left ventricular myocardium. (1987) (52)
- Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy. (2005) (52)
- Redistribution of connexin45 in gap junctions of connexin43-deficient hearts. (2002) (50)
- A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions (2011) (50)
- Remodeling of Gap Junctions in Ischemic and Nonischemic Forms of Heart Disease (2007) (49)
- Pathogenesis of Arrhythmogenic Cardiomyopathy. (2015) (48)
- Protein kinase Cε mediates salutary effects on electrical coupling induced by ischemic preconditioning (2007) (48)
- Beta-adrenergic and muscarinic cholinergic receptor densities in the human sinoatrial node: identification of a high beta 2-adrenergic receptor density. (1996) (48)
- The pathobiology of arrhythmogenic cardiomyopathy. (2011) (48)
- Role of the intercalated disc in cardiac propagation and arrhythmogenesis (2014) (47)
- Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations (2010) (47)
- Steroid withdrawal in the pediatric heart transplant recipient initially treated with triple immunosuppression. (1994) (47)
- Nontransmural laser treatment incompletely denervates canine myocardium. (1998) (45)
- Arrhythmogenic right ventricular cardiomyopathy mutations alter shear response without changes in cell-cell adhesion. (2014) (45)
- Effects of fiber type and training on beta-adrenoceptor density in human skeletal muscle. (1989) (44)
- Expression of Multiple Gap Junction Proteins in Human Fetal and Infant Hearts (1994) (44)
- Persistent lone atrial fibrillation: clinicopathologic study of 19 cases. (2014) (44)
- Pathophysiologic concentrations of lysophosphoglycerides quantified by electron microscopic autoradiography. (1984) (43)
- Noninvasive detection of rejection of transplanted hearts with indium-111-labeled lymphocytes. (1987) (41)
- Histopathological Characterization of Radiofrequency Ablation in Ventricular Scar Tissue. (2019) (41)
- The Arachidonic Acid Metabolic Capacity of Canine Myocardium is Increased during Healing of Acute Myocardial Infarction (1982) (41)
- Circulatory support with a centrifugal pump as a bridge to cardiac transplantation. (1989) (40)
- Morphological and membrane characteristics of spider and spindle cells isolated from rabbit sinus node. (2001) (39)
- Disseminated intravascular coagulation after administration of aprotinin in combination with deep hypothermic circulatory arrest. (1993) (37)
- Gap Junction Remodeling in a Case of Arrhythmogenic Right Ventricular Dysplasia Due to Plakophilin‐2 Mutation (2008) (37)
- Pathophysiology of myocardial reperfusion. (1987) (37)
- Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis. (1994) (37)
- Cardiac myocyte interconnections at gap junctions Role in normal and abnormal electrical conduction. (1992) (37)
- The role of altered intercellular coupling in arrhythmias induced by acute myocardial ischemia. (2001) (37)
- Protein kinase Cepsilon mediates salutary effects on electrical coupling induced by ischemic preconditioning. (2007) (36)
- Management during reoperation of aortocoronary saphenous vein grafts with minimal atherosclerosis by angiography. (1986) (36)
- Novel missense mutations in exon 15 of desmoglein-2: Role of the intracellular cadherin segment in arrhythmogenic right ventricular cardiomyopathy? (2010) (35)
- Disparate effects of different mutations in plakoglobin on cell mechanical behavior. (2008) (35)
- Diminished zonula occludens-1 expression in the failing human heart. (2007) (35)
- Detection of remote myocardial infarction with quantitative real-time ultrasonic characterization. (1988) (35)
- Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells (2016) (34)
- Utility of surveillance biopsies in infant heart transplant recipients. (1995) (34)
- Prolonged RV endocardial activation duration: a novel marker of arrhythmogenic right ventricular dysplasia/cardiomyopathy. (2009) (34)
- Cardiac intercellular communication: consequences of connexin distribution and diversity. (1995) (32)
- Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele. (2012) (32)
- Induction of Endothelial Cell Expression of the Plasminogen Activator Inhibitor Type 1 Gene by Thrombosis In Vivo (1992) (32)
- Arrhythmogenic right ventricular cardiomyopathy: new insights into mechanisms of disease. (2010) (32)
- Immunoelectron microscopic identification of cytoplasmic and nuclear Gsα in S49 lymphoma cells (1994) (31)
- Quantitative assessment of coronary artery plaque vulnerability by high‐resolution magnetic resonance imaging and computational biomechanics: A pilot study ex vivo (2005) (31)
- The Role of Endomyocardial Biopsy in ARVC: Looking Beyond Histology in Search of New Diagnostic Markers (2011) (30)
- Point of View Arrhythmogenesis and Ventricular Dysfunction After Myocardial Infarction Is Anomalous Cellular Coupling the Elusive Link? (1993) (30)
- Alterations of intercellular junctions induced by hypoxia in canine myocardium. (1990) (29)
- Autoradiographic delineation of skeletal muscle alpha 1-adrenergic receptor distribution. (1990) (29)
- Lysophospholipids, long chain acylcarnitines and membrane dysfunction in the ischaemic heart. (1987) (29)
- Retrograde Axonal Transport of 125I-Nerve Growth Factor in Rat Heal Mesenteric Nerves: Effect of Streptozocin Diabetes (1985) (29)
- Percutaneous transluminal angioplasty. Radiological-pathological correlation. (1981) (29)
- Deleterious effects of a systemic lytic state on reperfused myocardium. Minimization of reperfusion injury and enhanced recovery of myocardial function by direct angioplasty. (1995) (29)
- Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy (2021) (28)
- β‐Adrenergic and Muscarinic Cholinergic Receptor Densities in the Human Sinoatrial Node: (1996) (28)
- Unique epidermolytic bullous dermatosis with associated lethal cardiomyopathy related to novel desmoplakin mutations (2009) (28)
- CITED4 Protects Against Adverse Remodeling in Response to Physiological and Pathological Stress (2020) (28)
- The pathology of sudden cardiac death in patients with ischemic heart disease--arrhythmology for anatomic pathologists. (2005) (28)
- Adhesion Molecules: Why They Are Important to the Electrophysiologist (2006) (28)
- Arrhythmogenic cardiomyopathy: advances in diagnosis and disease pathogenesis. (2011) (27)
- Maximum-likelihood estimation applied to electron microscopic autoradiography (1985) (27)
- Spontaneous and inducible ventricular arrhythmias after myocardial infarction in mice. (2004) (26)
- Do alterations in intercellular coupling play a role in cardiac contractile dysfunction? (1998) (26)
- Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. (1990) (26)
- Compromise of beneficial effects of reperfusion on myocardium supplied by vessels with critical residual stenosis. (1988) (26)
- Subcellular distribution of endogenous long chain acylcarnitines during hypoxia in adult canine myocytes. (1993) (25)
- Expression of cathepsin K and tartrate-resistant acid phosphatase is not confined to osteoclasts but is a general feature of multinucleated giant cells: systematic analysis. (2013) (25)
- The biologic behavior of balloon hyperinflation-induced arterial lesions in hypercholesterolemic pigs depends on the presence of foam cells. (1995) (25)
- Heart transplantation in patients requiring preoperative mechanical support. (1987) (24)
- Skeletal muscle beta-adrenoceptor distribution and responses to isoproterenol in hyperthyroidism. (1992) (23)
- Connexins, Conduction, and Atrial Fibrillation (1998) (22)
- High resolution optical mapping reveals conduction slowing in connexin 43 deficient mice (2001) (21)
- Structural heart disease, SCN5A gene mutations, and Brugada syndrome: a complex ménage à trois. (2005) (21)
- Chapter 21 – Gap Junction Distribution and Regulation in the Heart (2004) (21)
- Echocardiographic characteristics of biopsy-proven cellular rejection in infant heart transplant recipients. (1996) (21)
- Cardiac structure and function in young and senescent mice heterozygous for a connexin43 null mutation. (2002) (19)
- Detection of Cardiac Transplant Rejection with Radiolabeled Lymphocytes (1982) (19)
- Anti-B-mediated rejection of an ABO-incompatible cardiac allograft despite aggressive plasma exchange transfusion. (1987) (18)
- Remodeling of Cell-Cell Junctions in Arrhythmogenic Cardiomyopathy (2014) (18)
- Retrograde axonal transport of 125I-nerve growth factor in rat ileal mesenteric nerves. Effect of streptozocin diabetes. (1985) (18)
- Structural Determinants of Slow Conduction in the Canine Sinus Node (1997) (17)
- Noninvasive detection of cardiac allograft rejection by analysis of the unipolar peak-to-peak amplitude of intramyocardial electrograms. (1989) (17)
- Arrhythmogenic Cardiomyopathy - New Insights into Disease Mechanisms and Drug Discovery. (2014) (17)
- Gap junctions, slow conduction, and ventricular tachycardia after myocardial infarction. (2012) (16)
- Genomic oncology education: an urgent need, a new approach. (2014) (16)
- Coronary atherosclerosis and thrombosis underlying acute myocardial infarction. (1987) (16)
- Expression of the Gs protein alpha-subunit disrupts the normal program of differentiation in cultured murine myogenic cells. (1997) (16)
- Gap junctions: functional effects of molecular structure and tissue distribution. (1997) (16)
- The changing face of cardiac transplantation: the Washington University Program, 1985-1987. (1988) (15)
- Sympathetic neural activity and the pathogenesis of sudden cardiac death. (2008) (15)
- Autoradiography of phosphatidyl choline. (1981) (15)
- Connexins, conduction, and atrial fibrillation. (2006) (15)
- Current results with triple therapy for heart transplantation. (1987) (15)
- Selective uptake of [3H]arachidonic acid into the dense tubular system of human platelets. (1987) (14)
- Biochemical and subcellular distribution of arachidonic acid in rat myocardium. (1987) (14)
- Gap junctions and arrhythmogenic cardiomyopathy. (2012) (14)
- Desmosome mutations in arrhythmogenic right ventricular cardiomyopathy: important insight but only part of the picture. (2009) (13)
- Non-ischemic left ventricular dysfunction after pediatric cardiac transplantation: treatment with plasmapheresis and OKT3. (2004) (13)
- Erratum: Murine γ-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-γ responsiveness: A new model for virus-induced vascular disease (1998) (13)
- Regulation of intercellular coupling in acute and chronic heart disease. (2000) (13)
- Douglas P. Zipes Lecture. Biology and pathobiology of cardiac connexins: from cell to bedside. (2006) (13)
- Quantification of intimal and medial thickness of human coronary arteries by acoustic microscopy (1990) (12)
- Surveillance for rejection by echocardiographically guided endomyocardial biopsy in the infant heart transplant recipient. (1991) (12)
- Association of calmodulin with isolated nuclei from rat hepatocytes. (1991) (12)
- Preservation of arachidonoyl phospholipids during tissue processing for electron microscopic autoradiography. (1985) (12)
- Repeated Simulated Ischemia and Protection Against Gap Junctional Uncoupling (2007) (12)
- 3D Computational Mechanical Analysis for Human Atherosclerotic Plaques Using MRI-Based Models with Fluid-Structure Interactions (2004) (12)
- Intramuscular administration of human tissue-type plasminogen activator in rabbits and dogs and its implications for coronary thrombolysis. (1987) (12)
- Connexin-40, bundle-branch block, and propagation at the Purkinje-myocyte junction. (2000) (12)
- Reduced plakoglobin immunoreactivity in arrhythmogenic cardiomyopathy: methodological considerations. (2013) (12)
- Reversible down-regulation of connexin43 expression in acute cardiac allograft rejection. (2001) (12)
- Distinct molecular signature of phospholamban p.Arg14del arrhythmogenic cardiomyopathy. (2019) (12)
- Myocyte interconnections at gap junctions and the development of anatomic substrates of ventricular arrhythmia's. (1994) (12)
- Monitoring of cardiac antirejection therapy with In-111 lymphocytes. (1982) (12)
- A high density in vitro extracellular electrode array: description and implementation. (1989) (11)
- Early postoperative care of the cardiac transplantation patient: routine considerations and immunosuppressive therapy. (1990) (10)
- Detection of thrombotic obstruction of a Björk-Shiley prosthesis by Doppler echocardiography. (1986) (10)
- Autopsy as a Source of Discovery in Cardiovascular Medicine: Then and Now. (2018) (10)
- The electrical heart: 25 years of discovery in cardiac electrophysiology, arrhythmias and sudden death. (2016) (10)
- Cell Adhesion Pathology (2007) (10)
- Nervous system transplantation in hydra (1972) (9)
- Structural and molecular determinants of intercellular coupling in cardiac myocytes (1995) (9)
- Metastatic peritoneal mesothelioma in the setting of recurrent ascites: A case report (2010) (8)
- Genomic pathology: a disruptive innovation. (2012) (8)
- Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC (2021) (8)
- Pediatric endomyocardial biopsy performed solely with echocardiographic guidance. (1993) (8)
- Altered Atrial Structure Begets Atrial Fibrillation, But How? (2004) (7)
- Modulation of Connexin43 Expression: (1995) (7)
- Early Lethality Due to a Novel Desmoplakin Variant Causing Infantile Epidermolysis Bullosa Simplex with Fragile Skin, Aplasia Cutis Congenita, and Arrhythmogenic Cardiomyopathy. (2020) (7)
- Arrhythmogenic Right Ventricular Cardiomyopathy (2009) (7)
- Amino Terminal 38.9% of Apolipoprotein B-100 Is Sufficient to Support Cholesterol-Rich Lipoprotein Production and Atherosclerosis (2003) (7)
- Use of single internal mammary artery grafts in older patients. (1990) (7)
- Distribution of alpha 1-adrenergic receptors in myocytic regions and vasculature of feline myocardium. (1989) (7)
- Subcellular compartmentalization of Gs alpha in cardiac myocytes and its redistribution in heart failure. (1996) (7)
- Cardiac sarcoidosis with severe involvement of the right ventricle: a case report (2015) (6)
- Closing the gap in understanding the regulation of intercellular communication. (2000) (6)
- End stage of arrhythmogenic cardiomyopathy with severe involvement of the interventricular septum. (2013) (6)
- Erratum: "Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy" (Science Translational Medicine (2014) 6:261 (261er6)) (2014) (5)
- Electrophysiologic properties and ventricular fibrillation in normal and myopathic hearts (1999) (5)
- Data acquisition system for maximum-likelihood analysis of electron microscopic autoradiographs. (1987) (5)
- Detection of rejection of canine orthotopic cardiac allografts with indium-111 lymphocytes and gamma scintigraphy. (1988) (5)
- Expression of multiple connexins by cells of the cardiovascular system and lens (1993) (5)
- Role of alpha- and beta-adrenergic receptor stimulation in the genesis of arrhythmias during myocardial ischaemia. (1986) (5)
- Expanding the spectrum of arrhythmogenic cardiomyopathy. (2008) (5)
- A personal computer based implementation of the maximum‐likelihood method of analysis of electron microscope autoradiographs (1992) (5)
- Mutations in desmosomal protein genes and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy. (2010) (5)
- Potential ablation of accessory atrioventricular pathways: injection of alcohol into the atrioventricular groove. (1994) (5)
- A fixation procedure suitable for autoradiography of endogenous long-chain acyl carnitine. (1985) (5)
- NONINVASIVE ASSESSMENT OF TREATMENT OF CARDIAC ALLOGRAFT REJECTION WITH INDIUM‐111-LABELED LYMPHOCYTES (1988) (5)
- Is CaMKII a therapeutic target for ventricular rate control? (2005) (5)
- Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia (vol 55, pg 587, 2010) (2010) (4)
- Prospective Evaluation of Clinico-pathological Predictors of Post-operative Atrial Fibrillation: An Ancillary Study from the OPERA Trial. (2020) (4)
- FK506--reversal of humorally mediated cardiac allograft rejection in the presence of preformed anti-class I antibody. (1993) (4)
- A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy. (2020) (4)
- Toward a unified concept of vascular smooth muscle response to injury. (1992) (4)
- Determinants of the distribution of radiolabeled congeners of tissue-type plasminogen activator and its modification for improved clot imaging (1992) (4)
- Pathobiology of Cardiovascular Diseases: Past, Present and Future Perspectives (CVP 25th Anniversary Special Review Article) The electrical heart: 25 years of discovery in cardiac electrophysiology, arrhythmias and sudden death (2016) (3)
- Molecular mechanisms in the pathogenesis of arrhythmogenic cardiomyopathy. (2017) (3)
- Abstract 13448: The Cardiac Sodium Nav1.5 Channelsome and Sudden Infant Death Syndrome (2010) (3)
- Nontransmural laser treatment incompletely denervates canine myocardium. Commentary (1998) (3)
- Electrophysiologic Remodeling: (1999) (3)
- Abstract 20589: Exercise and Mitochondrial Respiration in Mice with Arrhythmogenic Cardiomyopathy (2014) (3)
- Cardiac Ischemia Activates Calcium-independent Phospholipase A2β, Precipitating Ventricular Tachyarrhythmias in Transgenic Mice (2003) (2)
- Separation of transcriptively active and inactive chromatin. Agarose gel chromatography. (1978) (2)
- Protein trafficking in cardiovascular disease: How the science has evolved and where it must go. (2015) (2)
- Adrenergic Receptor Autoradiography and in Situ Hybridization (1994) (2)
- Remodeling of gap junctions in Naxos disease: a potential mechanism of lethal arrhythmias in arrhythmogenic right ventricular cardiomyopathy (2004) (2)
- Noninvasive quantification of myocardial beta-adrenergic receptors. A first step. (1993) (2)
- Autophagy and Reverse Remodeling: A New Biomarker in Heart Failure? (2022) (2)
- Focal adhesion kinase mediates stretch-induced up-regulation of electrical and mechanical junction proteins (2005) (1)
- DIAGNOSTIC AND PROGNOSTIC UTILITY OF RIGHT VENTRICULAR STRAIN IN ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY: A PROSPECTIVE MULTICENTER REGISTRY (2020) (1)
- Structure and function of cardiac gap junctions (2001) (1)
- Abstract 15042: Arrhythmogenic Cardiomyopathy Mutations Cause Disassembly of the Cx43 Forward Trafficking Machinery Which Can Be Rescued by GSK-3β Inhibition (2014) (1)
- Hydroxylapatite thermal fractionation of chromatin and DNA. (1978) (1)
- Reply to the Editor (1999) (1)
- A Link between Cardiac Myocytes and Collagen1 (1984) (1)
- Prospective Evaluation of Clinico-Pathological Predictors of Postoperative Atrial Fibrillation (2020) (1)
- Rejection in presensitized pediatric heart transplant recipients with a positive donor crossmatch utilizing perioperative plasmapharesis and cytolytic therapy (2005) (1)
- Mechanisms of arrhythmogenesis during chronic myocardial infarction. (1986) (1)
- evere cardiac phenotype with right ventricular predominance n a large cohort of patients with a single missense mutation in he DES gene (1)
- Attempted separation of transcriptively active and inactive chromatin by hydroxylapatite thermal chromatography. (1978) (1)
- Diseases of the Intercalated Disc (2017) (1)
- Erratum: Elevated donor cardiac troponin I: A marker of acute graft failure in infant heart recipients (Circulation (1994) 90 (2618-2621)) (1995) (1)
- Abstract 15076: Altered Trafficking of Junctional Proteins Mediated by SAP97 in Arrhythmogenic Cardiomyopathy (2013) (1)
- Electrophysiologic properties and ventricular fibrillation in normal and myopathic hearts. (1999) (1)
- Rapid Communication Subcellular Distribution of 32-Adrenergic Receptors Delineated With Quantitative Ultrastructural Autoradiography of Radioligand Binding Sites (2005) (1)
- Heterogeneous Transmural Distribution of -Adrenergic Receptor Subtpesin Failing HumanHearts (1993) (1)
- Gap Junctions in the Heart Effects of Mechanical Forces and Mediators of Hypertrophy on Remodeling of (2004) (1)
- Abstract 317: Cardiac-specific Deletion Of Desmoplakin Causes Dilated Cardiomyopathy And Remodeling Of Gap Junctions (2008) (1)
- Mechanisms of Altered Adrenergic Responsiveness Contributing to Arrhythmogenesis During Myocardial Ischemia (1989) (1)
- Analysis of buccal mucosa as a prognostic tool in children with arrhythmogenic cardiomyopathy (2021) (1)
- Nuclear receptors and a network biology approach to understanding and treating heart disease. (2019) (1)
- Monroe J. Schlesinger's Radiographic Visualization of the Coronary Arteries in Postmortem Hearts and Its Clinical Applications (2018) (1)
- Ventricular arrhythmias in a mouse model of vinculin-related cardiomyopathy (2005) (0)
- Mechano-electric coupling and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy (2011) (0)
- Abstract session 9: Genetic aspects of cardiac arrhythmias (2009) (0)
- DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, CARDIOVASCULAR, AND CANCER CENTER 2013-2014 SEMINAR SCHEDULE* Please obtain prior approval when inviting a guest speaker from Dr. Di Cera. DATE SPEAKER HOST (2014) (0)
- Connexins and Conduction (2000) (0)
- Abstract 13630: Wnt Activation Reverses Action Potential Phenotype and Decreased Sodium Current in Zebrafish Model of ARVC (2012) (0)
- Mediators of Cardiac Hypertrophy and Failure and Mechanical Forces Regulate Gap Junctional Conductance Regulatory Sites on Connexin Proteins , Connexin (2004) (0)
- Obituary for Dr. Jeffrey Michael Isner (2002) (0)
- Localization of beta-adrenergic receptors in transmural slices of myocardium with quantitative autoradiography (1986) (0)
- Sensitivity analysis of 3D MRI-based models for atherosclerotic plaques (2004) (0)
- Pathological Correlation After Cardiac Surgery (1992) (0)
- 963-21 Primary Angioplasty Minimizes Reperfusion Injury and Enhances Recovery of Myocardial Function Compared with Thrombolysis (1995) (0)
- Toward a clearer understanding of the link between viral infection of the heart and dilated cardiomyopathy. (1999) (0)
- Obituary for Frank Marcus, outstanding medical scientist of right ventricular dysplasia/cardiomyopathy. (2023) (0)
- AB23-4: Inhibition of Rho-family GTPases blocks stretch-induced up-regulation of cell-cell junction proteins and remodels adhesion junctions in cardiac myocytes (2006) (0)
- Markey Pathway Course in Heart Failure The Pathology of Heart Failure (2012) (0)
- Distribution of j3-Adrenergic Receptors in Failing Human Myocardium (2005) (0)
- Arrhythmia / Electrophysiology Connexin 43 Mutation Causes Heterogeneous Gap Junction Loss and Sudden Infant Death (2012) (0)
- CORONARY ARTERIES SUPPLY BLOOD TO THE HEART (2007) (0)
- Disparate biomechanical effects of two arrhythimogenic right ventricular cardiomyopathy-causing mutations in plakoglobin (2007) (0)
- Elevated plasma mitochondrial creatine kinase: An in vivo marker of irreversible injury (1982) (0)
- The Role of Galectin-3 in the Pathogenesis of Arrhythmogenic Cardiomyopathy - It's Complicated. (2021) (0)
- Abstract 2767: A New Diagnostic Test For Arrhythmogenic Right Ventricular Cardiomyopathy (2008) (0)
- HMS Task Force on Faculty Development and Diversity (2010) (0)
- Highlights of Heart Rhythm 2005, the Annual Scientific Sessions of the Heart Rhythm Society, May 4-7, 2005, New Orleans, Louisiana. (2005) (0)
- Abstract 12236: Redistribution of Gsk-3β to Cardiac Intercalated Discs in Arrhythmogenic Cardiomyopathy (2014) (0)
- Abstract of papers to be presented at the 31st annual scientific session of the American College of Cardiology Atlanta, Georgia, April 25–29, 1982Pathophysiological concentrations of lysophosphatides quantified by electron microscopic autoradiography (1982) (0)
- 321 Adaptive responses of gap junctional communication and increased myocyte survival with precoditioning (2003) (0)
- Connexin 43 expression and conduction velocity are reduced in plakoglobin-deficient mice: Implications for arrhythmogenesis in Naxos disease (2005) (0)
- Response by Thiene and Saffitz to Letter Regarding Article, "Autopsy as a Source of Discovery in Cardiovascular Medicine: Then and Now". (2019) (0)
- CARDIOVASCULAR PATHOLOGY (2 vols) (1983) (0)
- 71 Infarct healing and arrhythmias affected by gap junction remodelling in Cx43-deficient mice (2005) (0)
- Postmortem analysis of structural heart defects in fetuses and children by magnetic resonance imaging: an alternative to autopsy? (2014) (0)
- The role of immunohistochemistry in post-mortem diagnosis of arrhythmogenic right ventricular cardiomyopathy and guided family screening (2009) (0)
- GJA1-20k Rescues Cx43 Localization and Arrhythmias in Arrhythmogenic Cardiomyopathy. (2023) (0)
- Abstract 20776: Desmosomal Gene Mutations Perturb Myocardial Differentiation Through Complex Effects On Wnt Signaling (2010) (0)
- human platelets Selective uptake of (3H)arachidonic acid into the dense tubular system of (2011) (0)
- Validation of maximum-likelihood analysis of electron microscopic autoradiographs (1986) (0)
- human aorta Quantitative ultrasonic characterization of the nature of atherosclerotic plaques in (2011) (0)
- Highlights of Heart Rhythm 2006, the Annual Scientific Sessions of the Heart Rhythm Society: May 17 to 20, 2006, in Boston, Massachusetts (2006) (0)
- Management of Patients with Atherosclerotic Vein Grafts (1987) (0)
- Pathologic Basis of Conduction Disturbances: The Challenge to Move Beyond Microscopic Anatomy (2002) (0)
- Abstract 545: A Novel Mutation in Plakoglobin Blocks Up-Regulation of Intercellular Junction Proteins in Response to Mechanical Load (2006) (0)
- Remodelling of gap junctions in ventricular myocardium, effects of cell-to-cell adhesion, mediators of hypertrophy and mechanical forces (2011) (0)
- Cell–cell communication abnormalities (2005) (0)
- Early-onset multifocal inflammation inthetransforming growth factor131-null mouseislymphocyte mediated (1995) (0)
- Introduction to abstracts from the 8th Biennial Meeting of the International Society for Applied Cardiovascular Biology, St. Gallen, Switzerland, February 27–March 2, 2002 (2002) (0)
- D Computational Mechanical Analysis for Human Atherosclerotic Plaques Using MRI-Based Models with Fluid-Structure Interactions (2004) (0)
- Connexin and Infarction Connexin 43 as a Determinant of Myocardial Infarct Size Following Coronary Occlusion in Mice (2016) (0)
- Dr. Paul Eston Lacy, 1924–2005. (2005) (0)
- P3-11: PKCε-deficient mice show altered CX43 phosphorylation and distribution during ischemia and preconditioning (2006) (0)
- Abstract 18689: Building a High-throughput Assay for Arrhythmogenic Cardiomyopathy Modifier Pathways in the Zebrafish (2012) (0)
- Mechanisms Linking Desmosomal Gene Mutations and Exercise in Arrhythmogenic Right Ventricular Cardiomyopathy (2011) (0)
- PO-616-08 MECHANISMS OF IMMUNE-MEDIATED INJURY IN ARRHYTHMOGENIC CARDIOMYOPATHY (2022) (0)
- Infarct Healing and Arrhythmogenesis in Cx43-Deficient Mice (2003) (0)
- Effects of Angiotensin II on Expression of the Gap Junction Channel Protein Connexin 43 in Neonatal Rat Ventricular Myocytes (2016) (0)
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What Schools Are Affiliated With Jeffrey Ern Saffitz?
Jeffrey Ern Saffitz is affiliated with the following schools:
