Judson J. Van Wyk
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Biology
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Endocrinology
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Biology
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(Suggest an Edit or Addition)Judson J. Van Wyk's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Insulin-like growth factors as intraovarian regulators of granulosa cell growth and function. (1985) (929)
- Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay. (1977) (901)
- Dual control of cell growth by somatomedins and platelet-derived growth factor. (1979) (871)
- Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues. (1986) (529)
- Induction of immunoreactive somatomedin C human serum by growth hormone: dose-response relationships and effect on chromatographic profiles. (1980) (376)
- Monoclonal antibodies to receptors for insulin and somatomedin-C. (1983) (375)
- Reduction of plasma immunoreactive somatomedin C during fasting in humans. (1981) (368)
- Evaluation of acromegaly by radioimmunoassay of somatomedin-C. (1979) (357)
- Hormonal control of immunoreactive somatomedin production by cultured human fibroblasts. (1981) (309)
- Characterization of the insulin and somatomedin-C receptors in human placental cell membranes. (1974) (299)
- Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. (1983) (298)
- Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I. (1983) (295)
- Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. (1993) (292)
- Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats. (1983) (276)
- Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells. (1982) (258)
- Evidence for a functional role of endogenously produced somatomedinlike peptides in the regulation of DNA synthesis in cultured human fibroblasts and porcine smooth muscle cells. (1985) (255)
- The somatomedins: a family of insulinlike hormones under growth hormone control. (1974) (242)
- Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins. (1980) (238)
- Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency. (2000) (232)
- Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I. (1986) (225)
- Growth hormone dependence of somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II messenger ribonucleic acids. (1987) (197)
- Immunoreactive sites and accumulation of somatomedin-C in rat Sertoli-spermatogenic cell co-cultures. (1986) (188)
- Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling. (1981) (176)
- Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors. (1987) (168)
- Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor. (1985) (165)
- Somatomedin-C-mediated potentiation of follicle-stimulating hormone-induced aromatase activity of cultured rat granulosa cells. (1985) (165)
- Biphasic concentration dependency of stimulation of myoblast differentiation by somatomedins. (1986) (163)
- Somatomedin-C/insulin-like growth factor I as an enhancer of androgen biosynthesis by cultured rat ovarian cells. (1988) (159)
- Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor. (1985) (155)
- Virilizing adrenal hyperplasia; a genetic and hormonal study. (1956) (153)
- Evidence from radioligand assays that somatomedin-C and insulin-like growth factor-I are similar to each other and different from other somatomedins. (1980) (153)
- Somatomedin-C synergizes with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells. (1985) (151)
- Chromosomal sex in gonadal dysgenesis (ovarian agenesis): relationship to male pseudohermaphrodism and theories of human sex differentiation. (1955) (149)
- Somatomedin-C enhances induction of luteinizing hormone receptors by follicle-stimulating hormone in cultured rat granulosa cells. (1985) (147)
- Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. (1984) (147)
- Insulin-like growth factor stimulation of chondrocyte proteoglycan synthesis by human synovial fluid. (1989) (142)
- Serum concentrations of insulin-like growth factor II are not changed by short-term fasting and refeeding. (1988) (137)
- Insulin-like growth factor-I as an amplifier of follicle-stimulating hormone action: studies on mechanism(s) and site(s) of action in cultured rat granulosa cells. (1988) (136)
- Relationship of serum immunoreactive somatomedin-C to dietary protein and energy in growing rats. (1982) (133)
- Competitive binding of somatomedin to the insulin receptors of adipocytes, chondrocytes, and liver membranes. (1972) (129)
- Estradiol treatment of acromegaly. Reduction of immunoreactive somatomedin-C and improvement in metabolic status. (1980) (127)
- Factors controlling blood concentration of somatomedin C. (1984) (125)
- Partial characterization of a somatomedin-like peptide from the medium of cultured rat Sertoli cells. (1987) (124)
- Insulin-like growth factor II messenger ribonucleic acids are synthesized in the choroid plexus of the rat brain. (1988) (124)
- A novel role for somatomedin-C in the cytodifferentiation of the ovarian granulosa cell. (1984) (113)
- Isolation of rat testis cDNAs encoding an insulin-like growth factor I precursor. (1987) (113)
- Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids. (1988) (112)
- Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells. (1990) (110)
- Liberation of immunoreactive somatomedin-C from its binding proteins by proteolytic enzymes and heparin. (1983) (109)
- Effect of in vitro action of serum proteases or exposure to acid on measurable immunoreactive somatomedin-C in serum. (1983) (108)
- Serum immunoreactive somatomedin-C is elevated late in pregnancy. (1978) (106)
- Somatomedin‐C and platelet‐derived growth factor stimulate human fibroblast replication (1981) (106)
- The effects of a soybean product on thyroid function in humans. (1959) (104)
- Different half-lives of insulin-like growth factor I mRNAs that differ in length of 3' untranslated sequence. (1990) (101)
- Serum somatomedin-C in hypopituitarism and in other disorders of growth. (1977) (100)
- The use of adrenalectomy as a treatment for congenital adrenal hyperplasia. (1996) (98)
- Chromosomal sex in ovarian agenesis. (1954) (98)
- Insulin-like growth factor II binding to the type I somatomedin receptor. Evidence for two high affinity binding sites. (1986) (97)
- High incidence of perinatal insult in children with idiopathic hypopituitarism. (1980) (97)
- Characterization of a specific somatomedin-c receptor on isolated bovine growth plate chondrocytes. (1983) (91)
- Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle. (1980) (91)
- Explorations of the insulinlike and growth-promoting properties of somatomedin by membrane receptor assays. (1975) (89)
- Somatomedin-C and the assessment of growth. (1980) (89)
- Thyrotropin potentiation of insulin-like growth factor-I dependent deoxribonucleic acid synthesis in FRTL-5 cells: mediation by an autocrine amplification factor(s). (1990) (88)
- Insulin is essential for accumulation of casein mRNA in mouse mammary epithelial cells. (1981) (87)
- Follicle-stimulating hormone enhances somatomedin C binding to cultured rat granulosa cells. Evidence for cAMP dependence. (1986) (87)
- Stimulation of statural growth by recombinant insulin-like growth factor I in a child with growth hormone insensitivity syndrome (Laron type) (1992) (87)
- The role of bilateral adrenalectomy in the treatment of congenital adrenal hyperplasia. (2003) (87)
- On the nomenclature of the somatomedins and insulin-like growth factors. (1987) (86)
- Somatomedin C: restoration in vivo of cycle traverse in G0/G1 blocked cells of hypophysectomized animals. (1980) (84)
- Characterization and regulation of a specific cell membrane receptor for somatomedin-C/insulin-like growth factor I in cultured rat granulosa cells. (1988) (84)
- Insulin‐like growth factor‐I is expressed by avian flexor tendon cells (2000) (83)
- Epidermal growth factor (EGF) is required only during the traverse of early G1 in PDGF stimulated density-arrested BALB/c-3T3 cells. (1983) (79)
- Somatomedin: Inhibition of Adenylate Cyclase Activity in Subcellular Membranes of Various Tissues (1973) (75)
- The size heterogeneity of rat insulin-like growth factor-I mRNAs is due primarily to differences in the length of 3'-untranslated sequence. (1989) (74)
- Periarteritis nodosa; a case of fatal exfoliative dermatitis resulting from dilantin sodium sensitization. (1948) (74)
- Further evidence of a target organ defect in the syndrome of testicular feminization. (1966) (72)
- Insulinlike Growth Factor Action and Production in Adipocytes and Endothelial Cells From Human Adipose Tissue (1989) (71)
- Hyperprolactinemia is associated with increased immunoreactive somatomedin C in hypopituitarism. (1981) (67)
- Molecular basis of severe gynecomastia associated with aromatase expression in a fibrolamellar hepatocellular carcinoma. (1998) (67)
- Independent and synergistic actions of somatomedin-C in the stimulation of proteoglycan biosynthesis by cultured rat granulosa cells. (1986) (66)
- A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase. (1992) (64)
- Triiodothyronine stimulates cartilage growth and maturation by different mechanisms. (1987) (63)
- Synergistic Effect of Cortisol and Growth Hormone on Hepatic Ornithine Decarboxylase Activity 1 (1971) (63)
- Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and cyclic AMP. (1973) (62)
- Somatomedin-C as an amplifier of follicle-stimulating hormone action: enhanced accumulation of adenosine 3',5'-monophosphate. (1986) (62)
- Growth retardation in Cushing's syndrome. (1972) (62)
- Embryonic chick cartilage produces its own somatomedin-like peptide to stimulate cartilage growth in vitro. (1986) (61)
- Further purification and characterization of sulfation factor and thymidine factor from acromegalic plasma. (1971) (61)
- In vivo regulation of granulosa cell somatomedin-C/insulin-like growth factor I receptors. (1988) (61)
- Development of a heterologous radioimmunoassay for somatomedin C in sheep blood. (1982) (61)
- Hermaphroditism: classification, diagnosis, selection of sex and treatment. (1955) (60)
- Insulin-like growth factor I and insulin down-regulate growth hormone (GH) receptors in rat osteoblasts: evidence for a peripheral feedback loop regulating GH action. (1996) (56)
- Restoration of growth by human growth hormone (Roos) in hypopituitary dwarfs immunized by other human growth hormone preparations: clinical and immunological studies. (1974) (53)
- Paracrine functions of somatomedins. (1986) (53)
- Insulin-like growth factors and skeletal growth: possibilities for therapeutic interventions. (1999) (53)
- Growth hormone levels during sleep in normal and growth hormone deficient children. (1971) (53)
- Localization of somatomedin-C binding to bovine growth-plate chondrocytes in situ. (1986) (51)
- Thyrotropin and insulin-like growth factor I regulation of tyrosine phosphorylation in FRTL-5 cells. Interaction between cAMP-dependent and growth factor-dependent signal transduction. (1991) (51)
- Evidence that somatomedin-C is degraded by the kidney and inhibits insulin degradation. (1977) (51)
- Decreased serum somatomedin C concentrations during sleep: temporal relationship to the nocturnal surges of growth hormone and prolactin. (1981) (50)
- Early localization of 125-I-labelled human growth hormone in adrenals and other organs of immature hypophysectomized rats. (1971) (50)
- Relation between growth hormone and somatomedin. (1975) (49)
- Human somatomedin, the growth hormone dependent sulfation factor, is antilipolytic. (1972) (49)
- Prophylactic adrenalectomy of a three-year-old girl with congenital adrenal hyperplasia: pre- and postoperative studies. (1997) (46)
- Influence of hypothyroidism on growth hormone binding by rat liver. (1982) (44)
- The somatomedins. A new class of growth-regulating hormones? (1973) (41)
- Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity. (1971) (40)
- Ectopic thyroid glands simulating thyroglossal duct cysts. Hypothyroidism following surgical excision. (1969) (39)
- A bone disorder associated with copper deficiency. II. Histological and chemical studies on the bones. (1953) (38)
- A bone disorder associated with copper deficiency. I. Gross morphological, roentgenological, and chemical observations. (1953) (38)
- Multiple transcription start sites in the rat insulin-like growth factor-I gene give rise to IGF-I mRNAs that encode different IGF-I precursors and are processed differently in vitro. (1993) (37)
- Inhibition of BALB/c‐3T3 cells in late G1: Commitment to DNA synthesis controlled by somatomedin C (1981) (36)
- Expression of a biologically active analogue of somatomedin-C/insulin-like growth factor I. (1985) (35)
- Control of late G0/G1 progression and protein modification by SmC/IGF I. (1987) (35)
- Mitogenic activity of hydroxyapatite: Requirement for somatomedin C (1986) (34)
- Evidence for a direct effect of thyrotropin-releasing hormone (TRH) on prolactin release in humans. (1974) (33)
- Plasma somatomedin-C during the first year of life. (1982) (33)
- Structural characterization of exon 6 of the rat IGF-I gene. (1992) (32)
- The effect of pituitary stalk section on the adrenal function of women with cancer of the breast. (1960) (32)
- [Somatomedin inhibition of the growth hormone secretion stimulated by the hypothalamic factor somatocrinin or the synthetic peptide hpGRF]. (1982) (31)
- Islet cell function and glucose homeostasis in hypopituitary dwarfism: synergism between growth hormone and cortisone. (1973) (31)
- Partial purification of sulphation factor and thymidine factor from plasma. (1969) (27)
- Cushing's syndrome with a paradoxical response to dexamethasone. (1969) (27)
- Efficient purification of somatomedin-C/insulin-like growth factor I using immunoaffinity chromatography. (1985) (26)
- Stimulation by somatomedin-C of aminoisobutyric acid uptake in human fibroblasts: a possible test for cellular responsiveness to somatomedin. (1984) (25)
- Advancement of skeletal age of hypopituitary children treated with thyroid hormone plus cortisone. (1973) (25)
- Growth hormone, somatomedins, and growth failure. (1978) (25)
- Somatomedins (insulin-like growth factors), but not growth hormone, are mitogenic for chicken heart mesenchymal cells and act synergistically with epidermal growth factor and brain fibroblast growth factor. (1984) (25)
- Long-term hormonal regulation of the cAMP-specific phosphodiesterases in cultured FRTL-5 thyroid cells. (2001) (24)
- Creation of an autocrine model of insulin-like growth factor-I action in transfected FRTL-5 cells. (1992) (24)
- Elevated serum prolactin levels after pituitary-stalk section in man. (1972) (23)
- Demonstration of type I and type II somatomedin receptors on bovine growth plate chondrocytes (1988) (23)
- Partial characterization of sulphation and thymidine factors in acromegalic plasma. (1971) (23)
- Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis. (1985) (21)
- Synthetic somatomedin C: comparison with natural hormone isolated from human plasma. (1984) (18)
- The anemia of copper deficiency in dogs compared with that produced by iron deficiency. (1953) (17)
- Treatment of Cushing disease in Childhood with cyproheptadine. (1977) (17)
- On the nomenclature of the somatomedins and insulin-like growth factors. (1987) (16)
- The treatment of hyperthyroidism in childhood with thiouracil drugs. (1956) (16)
- Influence of pituitary stalk section on growth hormone, insulin and TSH secretion in women with metastatc breast cancer. (1969) (16)
- Assessment of the sella turcica volume in dwarfed children. (1973) (16)
- Marihuana smoking and pubertal arrest. (1980) (16)
- Interaction of secreted insulin-like growth factor-I (IGF-I) with cell surface receptors is the dominant mechanism of IGF-I's autocrine actions. (1992) (16)
- Synergistic interactions of somatomedin-C with adenosine 3',5'-cyclic monophosphate-dependent granulosa cell agonists. (1986) (15)
- Drug responses in hyperthyroid children suggesting an endogenous false transmitter (1968) (15)
- Cushing's syndrome with bilateral adrenal hyperplasia: a study of the plasma 17-hydroxycorticosteroids and the response to ACTH. (1955) (15)
- Radioimmunoassay of somatomedin‐C in the baboon (Papio cynocephalus): A comparison of multiple techniques of measurement (1983) (14)
- The effect of pituitary-stalk section on thyroid function and gonadotropic-hormone excretion in women with mammary carcinoma. (1962) (14)
- Failure of leucine, arginine, and epinephrine to alter plasma insulin levels in vitro. (1971) (13)
- Studies in hypoglycemia of infancy and childhood. Diagnosis and treatment. (1967) (12)
- The somatomedin group of peptide growth factors. (1978) (12)
- Interaction of the monoclonal antibodies alpha IR-1 and alpha IR-3 with insulin and somatomedin-C receptors. (1986) (11)
- Derivation of monoclonal antibodies to human somatomedin C/insulin-like growth factor I. (1987) (11)
- Molecular basis for species and ligand specificity of a monoclonal antibody raised against human IGF-I. (1997) (10)
- Common mechanism of action of somatomedin and insulin on fat cells. Further evidence. (1974) (10)
- Selection of Treatment in the Management of Thyrotoxicosis in Childhood and Adolescence (1978) (9)
- Genetic studies in a family with "simple" goiter. (1962) (9)
- Purification of somatomedin-C/insulin-like growth factor I. (1985) (9)
- Control of lens cell differentiation and ion fluxes by growth factors. (1986) (9)
- The luminosity and chromaticity of indicators as a function of pH. (1947) (8)
- Insulin-like growth factor I and the nutritional status of pygmies. (1982) (5)
- A technique for quantitative urine collection in the metabolic study of infants and young children. (1955) (3)
- Somatomedin-C: measurement by radioimmunoassay, regulatory mechanisms in humans and uses in clinical diagnosis. (1981) (3)
- Studies of the serum iodine containing components in a family of goiterous individuals. (1962) (3)
- Discussion Session 6. (1990) (2)
- Remembrances of our founders: will growth factors, oncogenes, cytokines, and gastrointestinal hormones return us to our beginnings? (1992) (1)
- Early recognition of cretinism. (1960) (1)
- On the nomenclature of the somatomedins and insulin-like growth factors. (1987) (1)
- Non-toxic goiters and thyrotoxicosis in childhood and adolescence. (1966) (0)
- The use of thyroid in pediatric practice. (1955) (0)
- Letter: Serum somatomedin-C in achondroplasia. (1976) (0)
- The evaluation of the endocrine patient: pediatric. (1958) (0)
- Preparation and evaluation of a sustained release potassium chloride tablet. (1972) (0)
- The present status of the treatment of virilizing adrenal hyperplasia with cortisone: experience of 3 1/2 years. (1954) (0)
- Hypothyroidism in childhood. (1956) (0)
- Ciba Foundation Colloquia on Endocrinology, Volume XII (1959) (0)
- The roles of somatomedins and other growth factors in growth and differentiation. (1988) (0)
- Structural and functional characterization of IGF-I RNA 3' variants. (1991) (0)
- 1995 John Howland Award Presentation to Floyd W. Denny, Jr (1995) (0)
- Peptide growth factors: a new frontier for pediatric endocrinology. (1986) (0)
- Thyroid problems in children. (1956) (0)
- [Somatomedin--somatomedin group within growth substances]. (1978) (0)
- Automatic weight control on a rotary tabletting machine using a digital measuring system. (1973) (0)
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