Jeffrey L. Benovic
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Jeffrey L. Benovicbiology Degrees
Biology
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#8051
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Molecular Biology
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#514
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Neuroscience
#627
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#654
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Biochemistry
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Biology
Jeffrey L. Benovic's Degrees
- PhD Biochemistry University of Pennsylvania
- Bachelors Chemistry University of Delaware
Why Is Jeffrey L. Benovic Influential?
(Suggest an Edit or Addition)Jeffrey L. Benovic's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin (1986) (1137)
- beta-Arrestin: a protein that regulates beta-adrenergic receptor function. (1990) (1127)
- β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor (1996) (1115)
- The role of receptor kinases and arrestins in G protein-coupled receptor regulation. (1998) (1108)
- Regulation of receptor trafficking by GRKs and arrestins. (2007) (657)
- Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. (1992) (652)
- Regulation of transmembrane signaling by receptor phosphorylation (1987) (589)
- Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. (1986) (581)
- Regulation of CXCR4 signaling. (2007) (561)
- Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting* (2001) (476)
- Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. (1996) (475)
- Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). (1987) (457)
- The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. (2003) (392)
- Synucleins Are a Novel Class of Substrates for G Protein-coupled Receptor Kinases* (2000) (381)
- Beta-adrenergic receptor kinase: primary structure delineates a multigene family. (1989) (377)
- Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors. (1990) (370)
- Arrestin Interactions with G Protein-coupled Receptors (1995) (358)
- Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. (1988) (347)
- Selective Regulation of Gαq/11 by an RGS Domain in the G Protein-coupled Receptor Kinase, GRK2* (1999) (332)
- Visual arrestin interaction with rhodopsin. Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin. (1993) (309)
- Trafficking of the HIV Coreceptor CXCR4 (1999) (289)
- The determination of the free magnesium level in the human red blood cell by 31P NMR. (1978) (269)
- Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling* (2010) (267)
- Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein. (1985) (264)
- G-protein-coupled receptors: turn-ons and turn-offs (1998) (263)
- Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin* (2000) (256)
- Arrestin/Clathrin Interaction (1997) (244)
- G-protein-coupled receptor kinase activity is increased in hypertension. (1997) (242)
- Regulation of G protein-coupled receptor kinases. (2000) (225)
- The ins and outs of G protein-coupled receptor trafficking. (2003) (224)
- Role of Clathrin-mediated Endocytosis in Agonist-induced Down-regulation of the β2-Adrenergic Receptor* (1998) (210)
- Arrestin function in G protein‐coupled receptor endocytosis requires phosphoinositide binding (1999) (206)
- Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis. (2002) (203)
- Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase. (1991) (203)
- Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. (1986) (203)
- Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. (2010) (202)
- Modulation of the Arrestin-Clathrin Interaction in Cells (1997) (198)
- Purification and characterization of beta-adrenergic receptor kinase. (1987) (195)
- Arrestin-2 Interacts with the Ubiquitin-Protein Isopeptide Ligase Atrophin-interacting Protein 4 and Mediates Endosomal Sorting of the Chemokine Receptor CXCR4* (2007) (190)
- The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system. (1984) (189)
- Arrestin/Clathrin Interaction (1997) (187)
- Differential Roles of Arrestin-2 Interaction with Clathrin and Adaptor Protein 2 in G Protein-coupled Receptor Trafficking* (2002) (186)
- Internalization of the m2 Muscarinic Acetylcholine Receptor (1997) (181)
- Regulation of G Protein-coupled Receptor Kinases by Caveolin* (1999) (179)
- P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms. (2005) (178)
- Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization. (1999) (178)
- Agonist-Receptor-Arrestin, an Alternative Ternary Complex with High Agonist Affinity* (1997) (177)
- Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. (1991) (177)
- Effect of Different G Protein-coupled Receptor Kinases on Phosphorylation and Desensitization of the -Adrenergic Receptor (*) (1996) (175)
- Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. (1987) (175)
- Regulation of G Protein-coupled Receptor Kinases by Calmodulin and Localization of the Calmodulin Binding Domain* (1997) (175)
- A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the beta 2-adrenergic receptor. (1994) (173)
- G-protein-coupled receptor kinases. (1991) (172)
- Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking. (2014) (171)
- Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase (1986) (168)
- The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. (1987) (165)
- The mammalian beta 2-adrenergic receptor: purification and characterization. (1984) (164)
- MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. (1999) (158)
- Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. (1985) (158)
- Desensitization and Internalization of the m2 Muscarinic Acetylcholine Receptor Are Directed by Independent Mechanisms * (1995) (156)
- Visualization of Agonist-induced Sequestration and Down-regulation of a Green Fluorescent Protein-tagged β2-Adrenergic Receptor* (1998) (155)
- The Dynamin-dependent, Arrestin-independent Internalization of 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptors Reveals Differential Sorting of Arrestins and 5-HT2A Receptors during Endocytosis* 210 (2001) (154)
- Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. (1986) (151)
- Interaction of Arrestins with Intracellular Domains of Muscarinic and α2-Adrenergic Receptors* (1997) (148)
- U50,488H-induced Internalization of the Human κ Opioid Receptor Involves a β-Arrestin- and Dynamin-dependent Mechanism (1999) (148)
- Polypeptide variants of beta-arrestin and arrestin3. (1993) (147)
- The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2. (1993) (146)
- Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family. (1993) (142)
- Nonvisual Arrestin Oligomerization and Cellular Localization Are Regulated by Inositol Hexakisphosphate Binding* (2006) (141)
- Mechanism of phosphorylation-recognition by visual arrestin and the transition of arrestin into a high affinity binding state. (1997) (140)
- Role of Arrestins in Endocytosis and Signaling of α2-Adrenergic Receptor Subtypes* (1999) (140)
- Mechanism of Quenching of Phototransduction (1997) (139)
- G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. (2000) (139)
- Arrestin-rhodopsin interaction. Multi-site binding delineated by peptide inhibition. (1994) (136)
- M3 Muscarinic Acetylcholine Receptor-Mediated Signaling Is Regulated by Distinct Mechanisms (2008) (135)
- Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle. (2000) (135)
- Regulation of the G Protein-coupled Receptor Kinase GRK5 by Protein Kinase C* (1997) (133)
- Binding and Phosphorylation of Tubulin by G Protein-coupled Receptor Kinases* (1998) (129)
- Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family. (1993) (129)
- The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. (1987) (127)
- Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein (2013) (127)
- Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors. (2005) (127)
- Regulation of G protein-coupled receptors by receptor kinases and arrestins. (1995) (126)
- Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking. (2000) (121)
- Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors. (1986) (119)
- Phosphorylation of the N-Formyl Peptide Receptor Carboxyl Terminus by the G Protein-coupled Receptor Kinase, GRK2 (*) (1995) (118)
- Safe use of the CXCR4 inhibitor ALX40-4C in humans. (2001) (114)
- Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation. (1993) (114)
- Arrestin-independent Internalization of the m1, m3, and m4 Subtypes of Muscarinic Cholinergic Receptors* (1998) (113)
- Cell-free expression of visual arrestin. Truncation mutagenesis identifies multiple domains involved in rhodopsin interaction. (1992) (113)
- Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5 (2017) (112)
- Agonist-dependent phosphorylation of the α2-adrenergic receptor by the β-adrenergic receptor kinase (1987) (112)
- G protein-coupled receptor kinases: Past, present and future. (2018) (111)
- A technique to harvest viable tracheobronchial epithelial cells from living human donors. (1992) (108)
- Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking* (2009) (108)
- Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development (2002) (106)
- Selective Regulation of Endogenous G Protein-coupled Receptors by Arrestins in HEK293 Cells* (2000) (106)
- beta-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation. (1988) (105)
- Mechanisms of acute desensitization of the beta2AR-adenylyl cyclase pathway in human airway smooth muscle. (1998) (104)
- Arrestin-2 and G Protein-coupled Receptor Kinase 5 Interact with NFκB1 p105 and Negatively Regulate Lipopolysaccharide-stimulated ERK1/2 Activation in Macrophages* (2006) (104)
- Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. (1999) (104)
- Arrestin Specificity for G Protein-coupled Receptors in Human Airway Smooth Muscle* 210 (2001) (103)
- Phosphorylation of chick heart muscarinic cholinergic receptors by the beta-adrenergic receptor kinase. (1989) (103)
- G Protein-coupled Receptor Kinase 2/Gαq/11Interaction: A NOVEL SURFACE ON A REGULATOR OF G PROTEIN SIGNALING HOMOLOGY DOMAIN FOR BINDING Gα SUBUNITS (2003) (102)
- Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. (1984) (102)
- Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5. (1994) (102)
- Mechanisms of agonist-induced down-regulation of the human kappa-opioid receptor: internalization is required for down-regulation. (2000) (101)
- Distinct Clathrin‐Coated Pits Sort Different G Protein‐Coupled Receptor Cargo (2006) (101)
- Identification of Gβγ Binding Sites in the Third Intracellular Loop of the M3-muscarinic Receptor and Their Role in Receptor Regulation* (2000) (101)
- l-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain (2005) (100)
- Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. (1988) (99)
- G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. (2000) (99)
- Role of the Differentially Spliced Carboxyl Terminus in Thromboxane A2 Receptor Trafficking (2001) (99)
- Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. (1989) (98)
- Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains. (1984) (98)
- Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase (1983) (98)
- Mutational Analysis of Gβγ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2* (2000) (98)
- Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5. (1994) (97)
- Structure and Function of the Third Intracellular Loop of the 5‐Hydroxytryptamine2A Receptor: The Third Intracellular Loop Is α‐Helical and Binds Purified Arrestins (1999) (97)
- G Protein-coupled Receptor Kinase GRK2 Is a Phospholipid-dependent Enzyme That Can Be Conditionally Activated by G Protein βγ Subunits* (1996) (96)
- Binding of wild type and chimeric arrestins to the m2 muscarinic cholinergic receptor. (1993) (93)
- Comparison ofR-, S-, andRS-albuterol interaction with human β1 and β2-adrenergic receptors (1996) (92)
- Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-Kinases (*) (1995) (91)
- Agonist-dependent Phosphorylation and Desensitization of the Rat A3 Adenosine Receptor (1995) (90)
- The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs* (2006) (90)
- β-arrestins and G protein-coupled receptor trafficking. (2014) (90)
- G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα. (2009) (90)
- Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine2A receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells (2001) (89)
- Arrestin2 expression selectively increases during neural differentiation (2004) (89)
- Receptor Docking Sites for G-protein βγ Subunits (1998) (89)
- Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor. (1999) (89)
- Mapping the Arrestin-Receptor Interface (2004) (88)
- β-arrestin–biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction (2016) (87)
- Lipid-mediated Regulation of G Protein-coupled Receptor Kinases 2 and 3 (*) (1995) (85)
- The Third Intracellular Loop of α2-Adrenergic Receptors Determines Subtype Specificity of Arrestin Interaction* (2002) (85)
- A Predicted Amphipathic Helix Mediates Plasma Membrane Localization of GRK5* (2004) (85)
- Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion. (1997) (84)
- Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. (2000) (83)
- Visual arrestin binding to rhodopsin. Intramolecular interaction between the basic N terminus and acidic C terminus of arrestin may regulate binding selectivity. (1994) (83)
- Molecular and regulatory properties of the adenylyl cyclase-coupled beta-adrenergic receptors. (1992) (83)
- Bimodal Regulation of the Human H1 Histamine Receptor by G Protein-coupled Receptor Kinase 2* (2005) (83)
- Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the beta-adrenergic receptor kinase. (1993) (81)
- Dual Regulation of EDG1/S1P1 Receptor Phosphorylation and Internalization by Protein Kinase C and G-protein-coupled Receptor Kinase 2* (2002) (80)
- Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6. (1994) (79)
- Expression and characterization of two beta-adrenergic receptor kinase isoforms using the baculovirus expression system. (1993) (79)
- Arrestin/Clathrin Interaction LOCALIZATION OF THE CLATHRIN BINDING DOMAIN OF NONVISUAL ARRESTINS TO THE CARBOXYL TERMINUS* (1997) (78)
- Molecular Basis for Subtype-specific Desensitization of Inhibitory Adenosine Receptors (1996) (77)
- Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells. (1987) (76)
- Mechanism of beta-adrenergic receptor kinase activation by G proteins. (1993) (76)
- A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization. (1997) (75)
- Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor. (1994) (74)
- Characterization of Dominant Negative Arrestins That Inhibit β2-Adrenergic Receptor Internalization by Distinct Mechanisms* (1998) (74)
- Regulation of heterotrimeric G protein signaling in airway smooth muscle. (2008) (73)
- Inhibition of the beta-adrenergic receptor kinase by polyanions. (1989) (73)
- Signaling and Phosphorylation-impaired Mutants of the Rat Follitropin Receptor Reveal an Activation- and Phosphorylation-independent but Arrestin-dependent Pathway for Internalization* (1998) (73)
- Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles. (1988) (71)
- Identification of βArrestin2 as a corepressor of androgen receptor signaling in prostate cancer (2009) (71)
- Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases. (1998) (71)
- Differentially regulated expression of the G-protein-coupled receptor kinases, betaARK and GRK6, during myelomonocytic cell development in vitro. (1996) (71)
- Novel β2-adrenergic receptor signaling pathways (2002) (70)
- [29] Arrestin: Mutagenesis, expression, purification, and functional characterization (2000) (70)
- Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia (2008) (69)
- Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. (1995) (69)
- β‐arrestin1 phosphorylation by GRK5 regulates G protein‐independent 5‐HT4 receptor signalling (2009) (68)
- Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. (2000) (68)
- c‐Src, Insulin‐Like Growth Factor I Receptor, G‐Protein‐Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes (2017) (67)
- Regulation of Arrestin-3 Phosphorylation by Casein Kinase II* (2002) (66)
- Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking. (2000) (65)
- Photoaffinity labelling of mammalian beta-adrenergic receptors: metal-dependent proteolysis explains apparent heterogeneity. (1983) (64)
- Coupling of M2 Muscarinic Receptors to Membrane Ion Channels via Phosphoinositide 3-Kinase γ and Atypical Protein Kinase C* (1999) (64)
- Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin. (2003) (62)
- Differential interaction of GRK2 with members of the Gαqfamily (2003) (62)
- Altered expression and subcellular distribution of GRK subtypes in the dopamine‐depleted rat basal ganglia is not normalized by l‐DOPA treatment (2008) (62)
- Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. (2009) (61)
- Development and Characterization of Pepducins as Gs-biased Allosteric Agonists*♦ (2014) (61)
- β-Arrestins and G protein-coupled receptor trafficking. (2013) (60)
- Magnetic resonance studies of the binding of ATP and cations to human hemoglobin. (1978) (59)
- Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels. (1999) (59)
- Arrestin/Clathrin Interaction LOCALIZATION OF THE ARRESTIN BINDING LOCUS TO THE CLATHRIN TERMINAL DOMAIN* (1997) (58)
- Regulation of Cysteinyl Leukotriene Type 1 Receptor Internalization and Signaling* (2005) (58)
- Rapid Agonist-induced Desensitization and Internalization of the A2B Adenosine Receptor Is Mediated by a Serine Residue Close to the COOH Terminus* (2001) (58)
- Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. (1987) (57)
- Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma (2017) (56)
- G Protein-coupled Receptor Kinase Interaction with Hsp90 Mediates Kinase Maturation* (2003) (56)
- Phosphorylation-Independent Desensitization of G Protein-Coupled Receptors? (2002) (54)
- High affinity binding of beta-adrenergic receptor kinase to microsomal membranes. Modulation of the activity of bound kinase by heterotrimeric G protein activation. (1996) (54)
- Haloperidol and Clozapine Differentially Affect the Expression of Arrestins, Receptor Kinases, and Extracellular Signal-Regulated Kinase Activation (2008) (53)
- Caenorhabditus elegans Arrestin Regulates Neural G Protein Signaling and Olfactory Adaptation and Recovery* (2005) (53)
- Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors. (2000) (53)
- Mutation of Individual Serine Residues in the C-terminal Tail of the Lutropin/Choriogonadotropin Receptor Reveal Distinct Structural Requirements for Agonist-induced Uncoupling and Agonist-induced Internalization* (1998) (53)
- Role of arrestins in G-protein-coupled receptor endocytosis. (1998) (53)
- Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. (1999) (53)
- Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. (1990) (53)
- Internalization of the Human Nicotinic Acid Receptor GPR109A Is Regulated by Gi, GRK2, and Arrestin3* (2010) (52)
- Homogeneous substrate-labeled fluorescent immunoassay for theophylline in serum. (1981) (51)
- Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A. (2007) (50)
- The β-Adrenergic Receptor Kinase (GRK2) Is Regulated by Phospholipids (*) (1995) (50)
- Electrostatic facilitation of the reaction catalyzed by the manganese-containing and the iron-containing superoxide dismutases. (1983) (50)
- Biological actions of formoterol isomers. (2002) (49)
- Development of a Yeast Bioassay to Characterize G Protein-coupled Receptor Kinases (2003) (49)
- Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms (2016) (47)
- Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma (2018) (47)
- beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation. (2009) (47)
- Structure-Function Analysis of G Protein-coupled Receptor Kinase-5 (1998) (47)
- Characterization of the GRK2 Binding Site of Gαq* (2004) (46)
- The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor* (2016) (46)
- Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine. (2001) (46)
- A new key in breast cancer metastasis. (2004) (45)
- Mapping the Arrestin-Receptor Interface STRUCTURAL ELEMENTS RESPONSIBLE FOR RECEPTOR SPECIFICITY OF ARRESTIN PROTEINS* (2003) (45)
- Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder (2011) (43)
- Arrestin: mutagenesis, expression, purification, and functional characterization. (2000) (43)
- G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits. (2003) (42)
- U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation. (1999) (42)
- A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes. (1999) (42)
- Structure of the human gene encoding the beta-adrenergic receptor kinase. (1994) (42)
- Altered Activity of Palmitoylation-deficient and Isoprenylated Forms of the G Protein-coupled Receptor Kinase GRK6* (1997) (42)
- Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells. (2001) (41)
- Faculty Opinions recommendation of Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor. (2010) (40)
- Enhanced expression of G protein‐coupled receptor kinase 2 selectively increases the sensitivity of A2A adenosine receptors to agonist‐induced desensitization (1998) (40)
- Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2. (2000) (40)
- Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death (2013) (40)
- Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors. (1995) (39)
- Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. (1983) (38)
- Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori (2009) (37)
- G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. (2011) (37)
- Association of the regulatory beta-adrenergic receptor kinase with rat liver microsomal membranes. (1994) (37)
- G Protein-coupled Receptor Kinase 5 Is Localized to Centrosomes and Regulates Cell Cycle Progression* (2012) (36)
- Selective Reduction in A2 Adenosine Receptor Desensitization Following Antisense‐Induced Suppression of G Protein‐Coupled Receptor Kinase 2 Expression (1999) (36)
- Suppression of G-protein–Coupled Receptor Kinase 3 Expression Is a Feature of Classical GBM That Is Required for Maximal Growth (2011) (34)
- Location of the allosteric site for 2,3-bisphosphoglycerate on human oxy- and deoxyhemoglobin as observed by magnetic resonance spectroscopy. (1979) (32)
- β-Adrenergic receptors and rhodopsin: shedding new light on an old subject (1986) (32)
- Receptor docking sites for G-protein betagamma subunits. Implications for signal regulation. (1998) (32)
- Structure/Function Analysis of α2A-Adrenergic Receptor Interaction with G Protein-coupledReceptor Kinase 2* (2005) (32)
- Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization (2015) (32)
- Characterization of the GRK2 binding site of Galphaq. (2004) (31)
- G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of β-Arrestin (2017) (30)
- Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling (2018) (30)
- Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase. (1986) (30)
- Molecular biology of adrenergic receptors. (1988) (30)
- Stereospecificity of the metal--adenosine 5'-triphosphate complex in reactions of muscle pyruvate kinase. (1979) (30)
- Comparison of R-, S-, and RS-albuterol interaction with human beta 1- and beta 2-adrenergic receptors. (1996) (30)
- cDNA cloning and chromosomal localization of the human α‐adrenergic receptor kinase (1991) (30)
- Dephosphorylation of the beta 2-adrenergic receptor and rhodopsin by latent phosphatase 2. (1988) (29)
- Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. (2018) (29)
- Purification and characterization of the beta-adrenergic receptor kinase. (1987) (29)
- G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. (1996) (29)
- Non-visual Arrestins Are Constitutively Associated with the Centrosome and Regulate Centrosome Function* (2010) (29)
- From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins. (2016) (29)
- Functional consequences of A1 adenosine-receptor phosphorylation by the beta-adrenergic receptor kinase. (1993) (29)
- Ischemic Inactivation of G Protein–Coupled Receptor Kinase and Altered Desensitization of Canine Cardiac &bgr;-Adrenergic Receptors (2000) (28)
- Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells. (1994) (28)
- Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases*♦ (2015) (28)
- Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation. (2000) (28)
- G Protein-coupled Receptor Kinase 5 Phosphorylates Nucleophosmin and Regulates Cell Sensitivity to Polo-like Kinase 1 Inhibition* (2012) (27)
- Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines (2017) (27)
- Mechanisms involved in adrenergic receptor desensitization. (1990) (27)
- Beta-adrenergic receptor kinase-1 acutely regulates PTH/PTHrP receptor signalling in human osteoblastlike cells. (1997) (25)
- Differential interaction of GRK2 with members of the G alpha q family. (2003) (25)
- Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells. (1995) (25)
- Chronic effects of catecholamines on the beta 2-adrenoreceptor system in cultured human airway epithelial cells. (1997) (25)
- [28] Purification and characterization of β-adrenergic receptor kinase (1991) (25)
- Effects of inflammation and acute beta-agonist inhalation on beta 2-AR signaling in human airways. (1996) (25)
- Magnetic resonance studies of the interaction of divalent metal cations with 2,3-bisphosphoglycerate. (1978) (24)
- Arrestin and the Multi-PDZ Domain-containing Protein MPZ-1 Interact with Phosphatase and Tensin Homolog (PTEN) and Regulate Caenorhabditis elegans Longevity*♦ (2010) (23)
- The mammalian beta-adrenergic receptor: structural and functional characterization of the carbohydrate moiety. (1987) (22)
- Regulation of G protein-coupled receptor function and expression (2000) (22)
- Analysis of G-protein-coupled receptor kinase RGS homology domains. (2004) (22)
- Internalization of the TXA2 Receptor α and β Isoforms (1999) (21)
- The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors. (1996) (20)
- G-Protein-Coupled Receptors Signal Victory (2012) (19)
- Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2. (2009) (19)
- Structure/Function Analysis of 2A-Adrenergic Receptor Interaction with G Protein-coupled Receptor Kinase 2* (2005) (19)
- Consequence of the tumor-associated conversion to cyclin D1b (2015) (18)
- G protein–coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor–promoted centrosomal separation (2013) (18)
- Modulation by GM1 ganglioside of beta 1-adrenergic receptor-induced cyclic AMP formation in Sf9 cells. (1995) (17)
- Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but β-arrestin-independent pathways. (2010) (16)
- Magnetic resonance and kinetic studies of the spatial arrangement of phosphoenolpyruvate and chromium (III)-adenosine diphosphate at the catalytic site of pyruvate kinase. (1978) (15)
- Differential expression of arrestins is a predictor of breast cancer progression and survival (2011) (15)
- Novel beta2-adrenergic receptor signaling pathways. (2002) (15)
- 1 Structural and Functional Analysis of a β 2-Adrenergic Receptor Complex with GRK 5 (2018) (14)
- Ubiquitination of G-protein-coupled receptors. (2004) (14)
- Molecular events associated with the regulation of signaling by M2 muscarinic receptors. (1999) (13)
- Regulation of G Protein Coupled Receptors (1997) (13)
- Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase. (1987) (13)
- Characterization of G protein-coupled receptor kinases. (2002) (13)
- Regulation of G protein-coupled receptors by agonist-dependent phosphorylation. (1990) (13)
- Characterization of arrestin expression and function. (2002) (12)
- G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel (2019) (12)
- Biased agonism at β-adrenergic receptors. (2020) (12)
- Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase). (1991) (12)
- Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. (1988) (12)
- Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. (2020) (11)
- Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking. (2002) (11)
- Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3. (2005) (11)
- Serum theophylline determination by fluorescence polarization immunoassay utilizing an umbelliferone derivative as a fluorescent label. (1981) (10)
- Identification and Characterization of Distinct C-Terminal Domains of the Human Hydroxycarboxylic Acid Receptor-2 That Are Essential for Receptor Export, Constitutive Activity, Desensitization, and Internalization (2012) (10)
- GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets. (2019) (10)
- High Affinity Binding of β-Adrenergic Receptor Kinase to Microsomal Membranes (1996) (10)
- Structural Domains Required for Caenorhabditis elegans G Protein-coupled Receptor Kinase 2 (GRK-2) Function in Vivo* (2012) (10)
- G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans (2017) (10)
- Expression of the beta-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells. (1994) (9)
- Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium. (1994) (9)
- Pepducins as a potential treatment strategy for asthma and COPD. (2018) (9)
- Identification and chromosomal localization of a processed pseudogene of human GRK6. (1997) (9)
- Control of the Cardiac Muscarinic K+ Channel by β-Arrestin 2* (2001) (8)
- Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma (2021) (8)
- Historical Perspective of the G Protein-Coupled Receptor Kinase Family (2021) (8)
- TWENTY QUESTIONS: THE STATE OF GPCR RESEARCH IN 2004 (2004) (7)
- G Protein-coupled Receptor Kinase 2/Gαq/11 Interaction (2003) (7)
- CHAPTER 13 – Structure and Function of Adrenergic Receptors: Models for Understanding G Protein-Coupled Receptors (1990) (7)
- Biochemical characterization of the adrenergic receptors: affinity labeling, purification, and reconstitution studies. (1985) (7)
- Synthetic peptides of the hamster P2-adrenoceptor as substrates and inhibitors of the 3-adrenoceptor kinase (2006) (7)
- G-Protein coupled receptor kinases mediate TNF alpha-induced NF kappaB signaling via direct interaction with and phosphorylation of I kappa B alpha (2009) (7)
- Molecular mechanisms of beta-adrenergic receptor desensitization. (1987) (6)
- Interleukins impair beta-adrenergic receptor adenylate cyclase (beta AR-AC) system function in human airway epithelial cells. (1995) (6)
- The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells. (1988) (6)
- Localization of the Sites for Ca 2+ -Binding Proteins on G Protein-Coupled Receptor (1998) (6)
- Targeting G protein-coupled receptor kinases (GRKs) to G protein-coupled receptors. (2021) (5)
- Atomic structure of G protein-coupled receptor kinase 5 (GRK5) reveals distinct structural features novel for GRKs (2015) (5)
- The Dynamin-dependent, Arrestin-independent Internalization of 5-Hydroxytryptamine 2A (5-HT 2A ) Serotonin Receptors Reveals Differential Sorting of Arrestins and 5-HT 2A Receptors (2001) (5)
- Differential agonist modulation of the cloned opioid receptors reveals distinct cellular mechanisms of receptor regulation (1994) (5)
- Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors. (2014) (4)
- B014: Ischemic inactivation of G protein-coupled receptor kinase and altered desensitization of canine cardiac β-adrenergic receptors (1998) (4)
- Arresting Developments in Biased Signaling. (2020) (3)
- Structure and Function of the Third Intracellular Loop of the 5-Hydroxytryptamine 2A Receptor: The Third Intracellular Loop Is a -Helical and Binds Purified Arrestins (1999) (3)
- Substrate labeled fluorescent immunoassay for quinidine (1981) (3)
- G-Protein-Coupled Receptor Kinases and Arrestins (2013) (3)
- Arrestin-independent internalization of muscarinic cholinergic receptors (1999) (3)
- Title Structure and Function of the Third Intracellular Loop of the 5-Hydroxytryptamine 2 A Receptor : The Third Intracellular Loop Is α-Helical and Binds Purified (1999) (3)
- Phenylalanine 193 in Extracellular Loop 2 of the β2-Adrenergic Receptor Coordinates β-Arrestin Interaction (2021) (3)
- 10 Regulation of Receptor Function (1987) (2)
- af-Agonist- andprostaglandin El-induced translocation ofthe ,/-adrenergic receptor kinase: Evidence thatthekinase may actonmultiple adenylate cyclase-coupled receptors (1986) (2)
- Targeting Oncogenic Gαq/11 in Uveal Melanoma (2021) (2)
- Inhibition of the @-Adrenergic Receptor Kinase by Polyanions* (2001) (2)
- NMR probes of the spatial arrangement of substrates at the active site of creatine kinase (1981) (2)
- Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4 (2021) (2)
- Substrate labeled fluorescent immunoassay for theophylline with very low caffeine cross reactivity (1982) (2)
- β -arrestin1 interacts with the G protein subunits β 1 γ 2 and promotes β 1 γ 2-dependent Akt signaling for NF- κ B activation (2009) (1)
- G Protein‐Coupled Receptor Kinase 6 (GRK6) Regulation of Insulin Processing and Secretion (2022) (1)
- JPET #131987 Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and ERK activation (2007) (1)
- PD 102807 Induces M3 mAChR-dependent GRK-/arrestin-biased Signaling in Airway Smooth Muscle Cells. (2022) (1)
- G-Protein coupled receptor kinases mediate TNF alpha-induced NF kappaB signaling via direct interaction with and phosphorylation of I kappa B alpha (38.15) (2009) (1)
- Structural biology: Arresting developments in receptor signalling (2015) (1)
- G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin (2022) (1)
- Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding. VOLUME 281 (2006) PAGES 9812-9823 (2006) (1)
- Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner (2022) (1)
- Negative Allosteric Modulation of Arrestin Recruitment to the β2‐Adrenergic Receptor (2019) (1)
- A NOVEL SURFACE ON A REGULATOR OF G PROTEIN SIGNALING HOMOLOGY DOMAIN FOR BINDING (2003) (1)
- The β-Adrenergic Receptor-Coupled Adenylate Cyclase: Reconstitution of the Functional Interactions of the Various Purified Components (1986) (1)
- G Protein-Coupled Receptor Kinases and Arrestins (2004) (1)
- Structural Basis for β-Arrestins in GPCR Trafficking (2017) (1)
- New frontiers in kinases. (2015) (1)
- G Protein-coupled Receptor Kinase GRK2 Is a Phospholipid-dependent Enzyme That Can Be Conditionally Activated by G Protein (cid:98)(cid:103) Subunits* (1996) (1)
- β2‐Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2‐adrenoceptor with possible implications for the treatment of asthma (2022) (1)
- Single amino acid substitution in visual arrestin quenches light-activated rhodopsin (1997) (1)
- Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2. (2022) (1)
- Abstract 578: β-arrestin-Biased β2-Adrenergic Receptor Signaling Enhances Cardiomyocyte Contractility via ROCK-Dependent Signaling (2018) (0)
- Diverse functional roles of negatively charged residues in arrestin C-terminus (1997) (0)
- Abstract 16831: β-Arrestin-Biased β2-Adrenergic Receptor Activation Confers Cardioprotection in Ischemia/Reperfusion Injury (2017) (0)
- CHAPTER 332 – Signaling Down the Endocytic Pathway (2003) (0)
- Phosphorylation / dephosphorylation of the jB-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution ( homologous desensitization / hormone receptor / receptor sequestration / protein phosphatase ) (0)
- f1-ADRENERGIC RECEPTORS (1988) (0)
- Call for papers! A special thematic compilation/special issue crossover with ACS Chemical Biology, ACS Medicinal Chemistry Letters, and the Journal of Medicinal Chemistry focused on new frontiers in kinases. (2014) (0)
- Very Few Arrestin Residues Determine Its Receptor Preference. (2004) (0)
- BETWEEN ARRESTIN AND TRANSDUCIN FOR PHOSPHORHODOPSIN Mechanism of Quenching of Phototransduction : BINDING COMPETITION (1997) (0)
- G Protein‐Coupled Receptor Kinase 2 (GRK2) is Localized to Centrosomes and Mediates Epidermal Growth Factor‐Promoted Separation of Duplicated Centrosomes (2013) (0)
- MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. (1999) (0)
- G-proteins | G Protein-Coupled Receptor Kinases and Arrestins (2021) (0)
- Molecular properties of beta 1 adrenergic and beta 2 adrenergic receptors revealed by photo affinity labeling (1982) (0)
- LBMON186 Beta-agonist Profiling Reveals Novel Biased Signaling Phenotypes For The Beta 2-adrenergic Receptor With Implications In The Treatment Of Asthma (2022) (0)
- Crystal structure of bovine arrestin-2 (2002) (0)
- β2‐Adrenergic Receptors Regulate Innate Immune Responses Through β‐Arrestin Dependent Pathways (2016) (0)
- Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6) (2006) (0)
- Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with Sangivamycin (2015) (0)
- Acknowledgment of Reviewers, 2019 (2019) (0)
- Abstract B27: Identification of uveal melanoma disseminated cancer cell dormancy mechanisms (2020) (0)
- Immunoassayfor Theophyllinein Serum (1981) (0)
- independent Internalization of 5-Hydroxytryptamine 2 A ( 5-HT 2 A ) Serotonin Receptors Reveals Differential Sorting of Arrestins and 5-HT 2 A Receptors during Endocytosis Permalink (2001) (0)
- Abstract 757: β-arrestin-Biased β2-Adrenergic Receptor Signaling Mediates Novel Mechanisms of Cardiomyocyte Contractility (2019) (0)
- The Functional Role of Arrestin Domain‐Containing Protein 3 in β2‐Adrenergic Receptor Endocytic Trafficking (2015) (0)
- Purification and reconstitution of the human platelet. cap alpha. /sub 2/-adrenergic receptor (1986) (0)
- Inhibition of fi-adrenergic receptor kinase prevents rapid homologous desensitization of f 82-adrenergic receptors ( A 431 celis / permeabilization / receptor phosphorylation / heparin ) (0)
- Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP (2006) (0)
- IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression. (2022) (0)
- Calmodulin interaction with GRK5 N‐terminus regulates kinase activation (2019) (0)
- G Protein‐Coupled Receptor Kinase 6 (GRK6) Regulation of Insulin Processing and Secretion (2021) (0)
- The state of GPCR research in 2004 ( 20 Questions ) (2004) (0)
- Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with AMP-PNP (2015) (0)
- af-Agonist-and prostaglandin El-induced translocation of the , /-adrenergic receptor kinase : Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors ( desensitization / receptor uncoupling / down-regulation ) (0)
- Abstract 580: A β-arrestin-Biased β2-Adrenergic Receptor-Specific Pepducin Confers Cardioprotection (2018) (0)
- Development of Gs‐biased modulators of the β2‐adrenergic receptor (662.1) (2014) (0)
- Isoproterenol enhances phosphorylation of pure β-adrenergic receptor by cAMP-dependent protein kinase (1984) (0)
- β‐Arrestin‐Biased β2‐Adrenergic Receptor Signaling Provides Cardioprotection in Ischemia/Reperfusion Injury (2017) (0)
- Effects of phospholipids on agonist-dependent phosphorylation of human muscarinic acetylcholine receptors by G protein-coupled receptor kinases: An alternate mode to kinase activation?☆ (1995) (0)
- Control of the cardiac muscarinic K+ channel by beta-arrestin 2. (2001) (0)
- Subject Index, Vol. 70, 1995 (1995) (0)
- Crystal Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) in Complex with Calmodulin (CaM) (2020) (0)
- j3-Adrenergic receptor kinase: Identification ofanovelprotein kinase thatphosphorylates theagonist-occupied form (1986) (0)
- Somatostatin Induces Translocation (2001) (0)
- GRK expression in GBM (2011) (0)
- Desensitization of the M2 muscarinic acetylcholine receptor: Effects of dominant-negative βARK1☆ (1995) (0)
- Kinase 1 Inhibition Regulates Cell Sensitivity to Polo-like Phosphorylates Nucleophosmin and G Protein-coupled Receptor Kinase 5 Cell (2012) (0)
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