June L. Biedler
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Why Is June L. Biedler Influential?
(Suggest an Edit or Addition)June L. Biedler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. (1989) (1738)
- Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. (1973) (1324)
- Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies. (1970) (781)
- Coordinate morphological and biochemical interconversion of human neuroblastoma cells. (1983) (602)
- Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. (1989) (494)
- Metaphase chromosome anomaly: association with drug resistance and cell-specific products. (1976) (383)
- Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers. (1987) (309)
- Vinblastine photoaffinity labeling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells. (1986) (267)
- Characteristics of stem cells from human neuroblastoma cell lines and in tumors. (2004) (231)
- A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture. (1976) (193)
- Human neuroblastoma I-type cells are malignant neural crest stem cells. (1995) (177)
- Characterization of human neuroblastoma cell lines established before and after therapy. (1986) (175)
- Potentiation of drug effect by Tween 80 in Chinese hamster cells resistant to actinomycin D and daunomycin. (1972) (174)
- Genes amplified and overexpressed in human multidrug-resistant cell lines. (1988) (173)
- Coordinate changes in neuronal phenotype and surface antigen expression in human neuroblastoma cell variants. (1987) (171)
- Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation (1989) (167)
- Trisomy of chromosome 15 in spontaneous leukemia of AKR mice. (1975) (159)
- Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells. (1993) (151)
- Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine. (1983) (148)
- A 22‐kd protein (sorcin/V19) encoded by an amplified gene in multidrug‐resistant cells, is homologous to the calcium‐binding light chain of calpain. (1986) (139)
- Cellular resistance to daunomycin in Chinese hamster cells in vitro. (1971) (134)
- A role for distinct cell types in determining malignancy in human neuroblastoma cell lines and tumors. (2003) (123)
- Presence and regulation of tyrosinase activity in human neuroblastoma cell variants in vitro. (1985) (121)
- Increased synthesis of a low molecular weight protein in vincristine-resistant cells. (1981) (119)
- Phenotype‐specific “tissue” transglutaminase regulation in human neuroblastoma cells in response to retinoic acid: Correlation with cell death by apoptosis (1992) (117)
- Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines (1986) (115)
- Membrane-mediated drug resistance and phenotypic reversion to normal growth behavior of Chinese hamster cells. (1975) (113)
- Gene rearrangement: a novel mechanism for MDR-1 gene activation. (1997) (106)
- Increased epidermal growth factor receptor in multidrug‐resistant human neuroblastoma cells (1988) (102)
- Nestin Is a Potential Mediator of Malignancy in Human Neuroblastoma Cells* (2004) (102)
- Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin. (1972) (101)
- Expression of stem cell factor and c-kit in human neuroblastoma. The Children's Cancer Group (1994) (99)
- Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells (1985) (97)
- Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas, and medullary thyroid cancers. (1991) (96)
- Drug resistance in Chinese hamster lung and mouse tumor cells. (1983) (96)
- The human non-muscle α-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells (2000) (89)
- Use of lipid vesicles as carriers to introduce actinomycin D into resistant tumor cells. (1976) (87)
- Drug resistance: genotype versus phenotype--thirty-second G. H. A. Clowes Memorial Award Lecture. (1994) (82)
- Specifically altered metaphase chromosomes in antifolate-resistant Chinese hamster cells that overproduce dihydrofolate reductase☆ (1980) (79)
- Somatic cell genetic analysis of human cell surface antigens: chromosomal assignments and regulation of expression in rodent-human hybrid cells. (1984) (74)
- Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases. (1980) (74)
- Brain-derived neurotrophic factor protects neuroblastoma cells from vinblastine toxicity. (1996) (72)
- Epidermal growth factor receptor is increased in multidrug-resistant Chinese hamster and mouse tumor cells. (1986) (69)
- Plasma membrane proteins and glycoproteins from Chinese hamster cells sensitive and resistant to actinomycin D. (1978) (68)
- Expression of stem cell factor and c-kit in human neuroblastoma. The Children's Cancer Group. (1994) (67)
- Genetic aspects of multidrug resistance (1992) (62)
- Transdifferentiation of human neuroblastoma cells results in coordinate loss of neuronal and malignant properties. (1988) (59)
- Sorcin (V19), a soluble acidic calcium-binding protein overproduced in multidrug-resistant cells. Identification of the protein by anti-sorcin antibody. (1987) (58)
- Cell lineage and differentiation state are primary determinants of MYCN gene expression and malignant potential in human neuroblastoma cells. (1997) (57)
- HuD, a neuronal-specific RNA-binding protein, is a putative regulator of N-myc pre-mRNA processing/stability in malignant human neuroblasts (1999) (54)
- Increased N-myc expression following progressive growth of human neuroblastoma. (1986) (48)
- Homogeneously Staining Regions and Double Minute Chromosomes, Prevalent Cytogenetic Abnormalities of Human Neuroblastoma Cells (1983) (43)
- Drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant Chinese hamster cells in vitro. (1972) (43)
- Human melanoma proteoglycan: expression in hybrids controlled by intrinsic and extrinsic signals. (1986) (43)
- Assignment of the gene for the beta subunit of thyroid-stimulating hormone to the short arm of human chromosome 1. (1986) (42)
- Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line. (1987) (39)
- HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells. (1997) (38)
- Chromosomal organization of amplified genes in multidrug-resistant Chinese hamster cells. (1988) (38)
- Reverse transformation of multidrug-resistant cells (1994) (37)
- SELECTION OF CHROMOSOMAL VARIANT IN AMETHOPTERIN-RESISTANT SUBLINES OF LEUKEMIA L1210 WITH INCREASED LEVELS OF DIHYDROFOLATE REDUCTASE. (1963) (37)
- Hybridization of actinomycin D- and amethopterin-resistant Chinese hamster cells in vitro. (1971) (35)
- CYTOGENETICS OF MOUSE LEUKEMIA L1210. I. ASSOCIATION OF A SPECIFIC CHROMOSOME WITH DIHYDROFOLATE REDUCTASE ACTIVITY IN AMETHOPTERIN-TREATED SUBLINES. (1965) (34)
- Differential collagen biosynthesis by human neuroblastoma cell variants. (1987) (34)
- Role of human chromosome 11 in determining surface antigenic phenotype of normal and malignant cells. Somatic cell genetic analysis of eight antigens, including putative human Thy-1 (1985) (31)
- Multidrug resistance in human neuroblastoma cells. (1991) (31)
- Gene amplification accompanies low level increases in the activity of dihydrofolate reductase in antifolate-resistant Chinese hamster lung cells containing abnormally banding chromosomes (1982) (31)
- Trisomy of chromosome 15 in x-ray induced mouse leukemia. Abstr. (1977) (30)
- ASSOCIATION OF INCREASED DIHYDROFOLATE REDUCTASE LEVELS AND CHROMOSOME ALTERATION IN AMETHOPTERIN-RESISTANT SUBLINES OF LEUKEMIA L1210. (1963) (30)
- Replication pattern of a large homogenously staining chromosome region in antifolate‐resistant Chinese hamster cell lines (1981) (27)
- The fine structure of continuous human neuroblastoma lines SK-N-SH, SK-N-BE(2), and SK-N-MC (1981) (27)
- Antifolate-resistant Chinese Hamster Cells. mRNA directed overproduction of multiple dihydrofolate reductases from a series of independently derived sublines containing amplified dihydrofolate reductase genes. (1982) (26)
- Loss of one HuD allele on chromosome #1p selects for amplification of the N-myc proto-oncogene in human neuroblastoma cells (2006) (25)
- Assignment of human nerve growth factor receptor gene to chromosome 17 and regulation of receptor expression in somatic cell hybrids (1986) (25)
- In vivo uptake of carbon-14-colchicine for identification of tumor multidrug resistance. (1994) (25)
- Biochemical and karyological properties of cells resistant to the quinazoline antifolate, methasquin. (1978) (23)
- 4 – Cellular Concomitants of Multidrug Resistance (1988) (23)
- Multidrug-resistant human neuroblastoma cells are more differentiated than controls and retinoic acid further induces lineage-specific differentiation. (1991) (23)
- Antifolate-resistant chinese hamster cells. Evidence from independently derived sublines for the overproduction of two dihydrofolate reductases encoded by different mRNAs. (1980) (20)
- Differentiation-inducing agents stably convert human neuroblastoma I-type cells to neuroblastic (N) or nonneuronal (S) neural crest cells. (1994) (20)
- In-Vivo Identification of Tumor Multidrug Resistance with Tritium-3-Colchicine (1992) (20)
- Differential drug sensitivity of human neuroblastoma cells. (1986) (20)
- Glucocorticoids induce neuroendocrine cell differentiation and increase expression of N-myc in N-type human neuroblastoma cells. (2002) (19)
- Ganglioside composition of malignant and actinomycin D-resistant nonmalignant Chinese hamster cells. (1979) (18)
- A corrected karyotype for the SH-SY5Y human neuroblastoma cell line. (2002) (17)
- Chromosome Abnormalities in Human Tumor Cells in Culture (1975) (17)
- Actinomycin‐D‐resistant in vitro mouse cell line derived from a methylcholanthrene‐induced sarcoma: Decrease of malignancy and antigenic characteristics (1974) (16)
- Molecular and Cytogenetic Analysis of Multidrug Resistance-Associated Gene Amplification in Chinese Hamster, Mouse Sarcoma, and Human Neuroblastoma Cells (1991) (15)
- Amethopterin resistance in clonal lines of L1210 mouse leukemia: some associated biologic and biochemical alterations. (1966) (14)
- Differential expression of intermediate filaments and fibronectin in human neuroblastoma cells. (1988) (13)
- Multipotent capacity of morphologically intermediate (I-type) human neuroblastoma cells after treatment with differentiation-inducing drugs. (1991) (13)
- Modification of characteristics of an in vitro mouse cell line after an increase of its tumor-producing capacity. (1961) (12)
- A comparison of the effects of 4-amino-N10-methyl-pteroylglutamic acid and 2,6-diaminopurine upon sensitive and resistant sublines of a strain of mouse leukemia. (1951) (10)
- Cell surface antigen of human neuroblastomas is related to nuclear antigen of normal cells. (1985) (10)
- The effects of 4-amino-N10 methyl-pteroylglutamic acid on the leukocytes of the normal and leukemic mouse. (1950) (10)
- Chromosomal localization of the murine RFC-1 gene encoding a folate transporter and its amplification in an antifolate resistant variant overproducing the transporter. (1998) (8)
- Biopterin content of human neuroblastoma cells in culture. (1978) (8)
- In vivo imaging and specific targeting of P-glycoprotein expression in multidrug resistant nude mice xenografts with [125I]MRK-16 monoclonal antibody. (1995) (8)
- Growth stage-related synthesis and secretion of proteins by human neuroblastoma cells and their variants. (1985) (8)
- Association of sorcin with drug resistance in L1210 cells (2004) (8)
- Three human cell surface antigen systems determined by genes on chromosome 12 (1984) (7)
- Radiation-induced murine leukemia ERLD in cell culture. (1976) (7)
- Cellular maturation and oncogene expression during drug-induced differentiation in vitro: a brief review. (1990) (7)
- In-vivo identification of tumor multidrug resistance with 3H-colchicine [corrected]. (1992) (7)
- Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay. (1996) (6)
- Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II. (1991) (5)
- Reduced tumorigenicity of syngeneic mouse sarcoma cells resistant to actinomycin d and ethidium bromide. Abstr. (1973) (5)
- Expression of a melanocyte phenotype in human neuroblastoma cells in vitro. (1985) (5)
- Disappearance of resistant mutants in leukemic cell population. Abstr. (1964) (4)
- The effects of triethylene melamine and related compounds on the leukocytes of mouse leukemia. (1951) (4)
- Human neuroblastoma lines respond differently to diverse differentiation-inducing agents. (1994) (4)
- Evidence for reverse transformation in multidrug-resistant human neuroblastoma cells. (1988) (4)
- Protein Changes in Multidrug-Resistant Cells (1991) (3)
- Overproduction of dihydrofolate reductase by antifolate resistant Chinese hamster cells (1978) (3)
- Genetics of drug resistance. (1994) (3)
- Cytogenetics of Mouse Leukemia L 1210 I . Association of a Specific Chromosome with Dihydrofolate Reductase Activity in Amethopterin-treated 2 (2006) (2)
- Permanent phenotypic conversion of human neuroblastoma I-type cells (1993) (2)
- Specificity of compaction in meiotic chromosomes of the female Chinese hamster (1973) (2)
- Repetitive DNA sequences in methotrexate- and methasquin-sensitive and -resistant Chinese hamster cell lines (1980) (2)
- [Antineoplastic drugs: cross resistance in studies on cell cultures]. (1971) (1)
- Microarray analyses reveals “what’s up” in human neuroblastoma malignant stem cells (2006) (1)
- Further studies on dopamine-beta-hydroxylase in neuroblastoma. Abstr. (1973) (1)
- Cells from Vinblastine Toxicity Brain-derived Neurotrophic Factor Protects Neuroblastoma (2006) (0)
- AMPLIFICATION OF DIHYDROFOLATE REDUCTASE GENES IN ANTIFOLATE RESISTANT CHINESE HAMSTER LUNG FIBROBLASTS (1980) (0)
- P40 30 TP – RESPONSE OF MULTIDRUG RESISTANT CELLS TO HYPERTHERMIA (1991) (0)
- Cytogenetic Consequences of Gene Amplification (2020) (0)
- Reverse transformation of multidrug-resistant human neuroblastoma stem cells is associated with up-regulation of CD133 and ABCG2, markers of a less differentiated, less malignant cell phenotype (2006) (0)
- The neuronal-specific RNA binding protein HuD regulates N-myc pre-mRNA stability and gene copy number in human neuroblastoma cells (2005) (0)
- Expression of Distinct Neural Crest Lineages Phenotypic Diversification in Human Neuroblastoma Cells : Updated (2006) (0)
- Evidence for the overproduction of two dihydrofolate reductases encoded by separate mRNAs in antifolate-resistant Chinese hamster cells (1979) (0)
- Amethopterin Resistance in Gloria! Lines of L1210 Mouse Leukemia: Some Associated Biologic and Biochemical Alterations1 (2006) (0)
- Fish and CGH studies of gene rearrangement and amplification in drug resistance (1997) (0)
- Surface markers of neuroectoderm-derived human tumors: In vitro models of cellular differentiation (1985) (0)
- Further observations on the control of dihydrofolic reductase in l1210 mouse leukemia. Abstr. (1963) (0)
- Specific cytogenetic abnormality (trisomy of chromsome 15) in akr mouse leukemia. Abstr. (1975) (0)
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