James L. Maller
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James L. Mallerbiology Degrees
Biology
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Molecular Biology
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Neuroscience
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Biochemistry
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Biology
James L. Maller's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Molecular Biology Stanford University
Why Is James L. Maller Influential?
(Suggest an Edit or Addition)James L. Maller's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase (1990) (941)
- Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II (1988) (913)
- Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2 + (1988) (824)
- Purification of maturation-promoting factor, an intracellular regulator of early mitotic events. (1988) (639)
- Cyclin is a component of maturation-promoting factor from Xenopus (1990) (622)
- Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. (2001) (578)
- Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. (1999) (545)
- Progesterone-stimulated meiotic cell division in Xenopus oocytes. Induction by regulatory subunit and inhibition by catalytic subunit of adenosine 3':5'-monophosphate-dependent protein kinase. (1977) (405)
- Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts (1985) (388)
- A Novel Mechanism for Activation of the Protein Kinase Aurora A (2003) (361)
- Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity. (1992) (314)
- Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase. (1993) (308)
- Regulation of oocyte maturation. (1980) (307)
- Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase. (1993) (284)
- Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle (1989) (263)
- Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs. (2003) (259)
- Activated Polo-Like Kinase Plx1 Is Required at Multiple Points during Mitosis in Xenopus laevis (1998) (259)
- Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis (1989) (257)
- Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells (1989) (238)
- Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes. (1977) (237)
- A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. (1988) (237)
- The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90Rsk (2000) (230)
- A Centrosomal Localization Signal in Cyclin E Required for Cdk2-Independent S Phase Entry (2004) (212)
- Early effect of progesterone on levels of cyclic adenosine 3':5'-monophosphate in Xenopus oocytes. (1979) (199)
- Progesterone inhibits adenylate cyclase in Xenopus oocytes. Action on the guanine nucleotide regulatory protein. (1981) (192)
- cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. (1992) (188)
- Role for cyclin A in the dependence of mitosis on completion of DMA replication (1991) (185)
- Cyclin B in Xenopus oocytes: implications for the mechanism of pre‐MPF activation. (1991) (172)
- In vivo regulation of the early embryonic cell cycle in Xenopus. (1996) (168)
- Induction of Xenopus oocyte meiotic maturation by MAP kinase. (1995) (165)
- Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk. (1999) (162)
- Maternal Xenopus Cdk2-Cyclin E Complexes Function during Meiotic and Early Embryonic Cell Cycles That Lack a G1 Phase (*) (1995) (161)
- The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes. (2001) (161)
- A protein kinase from Xenopus eggs specific for ribosomal protein S6. (1985) (160)
- Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts. (1996) (159)
- Calcium Elevation at Fertilization Coordinates Phosphorylation of XErp1/Emi2 by Plx1 and CaMK II to Release Metaphase Arrest by Cytostatic Factor (2005) (157)
- Mitotic Effects of a Constitutively Active Mutant of the Xenopus Polo-Like Kinase Plx1 (1999) (153)
- Xenopus oocytes and the biochemistry of cell division. (1990) (149)
- Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases (1994) (141)
- Regulation of Xenopus Aurora A Activation by TPX2* (2004) (140)
- Regulation of amphibian oocyte maturation. (1985) (137)
- Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6. (1986) (133)
- Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity. (1995) (131)
- Identification of a steroid receptor on the surface of Xenopus oocytes by photoaffinity labeling. (1982) (128)
- Ionizing radiation induces apoptosis and elevates cyclin A1-Cdk2 activity before but not after the midblastula transition in Xenopus. (1997) (127)
- Purification and cloning of a protein kinase that phosphorylates and activates the polo-like kinase Plx1. (1998) (126)
- Activation of the anaphase-promoting complex and degradation of cyclin B is not required for progression from Meiosis I to II in Xenopus oocytes (2001) (125)
- A study of the induction of cell division in amphibian oocytes by insulin. (1981) (122)
- Identification of Novel Phosphorylation Sites on Xenopus laevis Aurora A and Analysis of Phosphopeptide Enrichment by Immobilized Metal-affinity Chromatography * (2003) (118)
- Increased phosphorylation of ribosomal protein S6 during meiotic maturation of Xenopus oocytes. (1982) (116)
- Zygotic transcription is required to block a maternal program of apoptosis in Xenopus embryos. (1997) (116)
- Bub1 is activated by the protein kinase p90Rsk during Xenopus oocyte maturation (2001) (113)
- The Spindle Checkpoint Kinase Bub1 and Cyclin E/Cdk2 Both Contribute to the Establishment of Meiotic Metaphase Arrest by Cytostatic Factor (2002) (109)
- Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1. (1995) (109)
- The role of Xenopus membrane progesterone receptor beta in mediating the effect of progesterone on oocyte maturation. (2007) (107)
- Mos proto-oncogene function during oocyte maturation in Xenopus. (1996) (106)
- Repo-Man Controls a Protein Phosphatase 1-Dependent Threshold for DNA Damage Checkpoint Activation (2009) (104)
- Spindle formation and cleavage in Xenopus eggs injected with centriole-containing fractions from sperm. (1976) (102)
- In vivo regulation of cyclic AMP phosphodiesterase in Xenopus oocytes. Stimulation by insulin and insulin-like growth factor 1. (1987) (97)
- Requirement for Cdk2 in cytostatic factor-mediated metaphase II arrest. (1993) (95)
- Cloning and Characterization of a Novel Serine/Threonine Protein Kinase Expressed in Early Xenopus Embryos* (1996) (94)
- The cyclin B2 component of MPF is a substrate for the c-mosxe proto-oncogene product (1990) (94)
- Two distinct mechanisms control the accumulation of cyclin B1 and Mos in Xenopus oocytes in response to progesterone. (1999) (90)
- Activation of p34cdc2 kinase by cyclin A (1991) (89)
- Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions (1991) (87)
- A maternal form of the phosphatase Cdc25A regulates early embryonic cell cycles in Xenopus laevis. (1999) (87)
- Metaphase protein phosphorylation in Xenopus laevis eggs (1987) (86)
- Induction of meiotic maturation in Xenopus oocytes by 12-O-tetradecanoylphorbol 13-acetate. (1987) (85)
- A role for cyclin E/Cdk2 in the timing of the midblastula transition in Xenopus embryos. (1997) (82)
- In vivo phosphorylation and activation of ribosomal protein S6 kinases during Xenopus oocyte maturation. (1989) (81)
- Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II. (1991) (78)
- The elusive progesterone receptor in Xenopus oocytes. (2001) (78)
- Direct evidence for tyrosine and threonine phosphorylation and activation of mitogen-activated protein kinase by vasopressin in cultured rat vascular smooth muscle cells. (1993) (76)
- Spindle Pole Regulation by a Discrete Eg5-Interacting Domain in TPX2 (2008) (74)
- Progesterone inhibition of Xenopus oocyte adenylate cyclase is not mediated via the Bordetella pertussis toxin substrate. (1984) (73)
- Microinjection of pp60v-src into Xenopus oocytes increases phosphorylation of ribosomal protein S6 and accelerates the rate of progesterone-induced meiotic maturation (1984) (70)
- Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest (2003) (69)
- The effect of insulin on intracellular ph and ribosomal protein S6 phosphorylation in oocytes of Xenopus laevis. (1984) (66)
- Inhibition of Xenopus oocyte adenylate cyclase by progesterone and 2',5'-dideoxyadenosine is associated with slowing of guanine nucleotide exchange. (1983) (66)
- Maturation-promoting factor and the regulation of the cell cycle (1989) (64)
- Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex. (1992) (64)
- A cdc2-related kinase oscillates in the cell cycle independently of cyclins G2/M and cdc2. (1992) (63)
- Serine/threonine phosphatases in the DNA damage response and cancer (2010) (62)
- Cdc2-Cyclin B Phosphorylates p70 S6 Kinase on Ser411at Mitosis* (1998) (61)
- Mitotic control. (1991) (60)
- Regulation of mitogen-activated protein kinase activation by protein kinases A and C in a cell-free system. (1994) (60)
- Antibodies to Xenopus egg S6 kinase II recognize S6 kinase from progesterone- and insulin-stimulated Xenopus oocytes and from proliferating chicken embryo fibroblasts (1987) (59)
- Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle. (1992) (58)
- MAP kinase is activated during mesoderm induction in Xenopus laevis. (1994) (57)
- Studies of a plasma membrane steroid receptor in Xenopus oocytes using the synthetic progestin RU 486. (1985) (57)
- The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication (2010) (57)
- The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage. (2001) (57)
- Calcium, Calmodulin, and CaMKII Requirement for Initiation of Centrosome Duplication in Xenopus Egg Extracts (2002) (56)
- Recurring themes in oocyte maturation. (1998) (56)
- The DNA damage checkpoint in embryonic cell cycles is dependent on the DNA-to-cytoplasmic ratio. (2004) (55)
- Cyclin E-dependent localization of MCM5 regulates centrosome duplication (2008) (55)
- A similar pool of cyclic AMP phosphodiesterase in Xenopus oocytes is stimulated by insulin, insulin-like growth factor 1, and [Val12,Thr59]Ha-ras protein. (1989) (54)
- Centrosomal Localization of Cyclin E-Cdk2 Is Required for Initiation of DNA Synthesis (2010) (53)
- Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts. (2002) (53)
- Phosphorylation of ribosomal protein S6 on serine after microinjection of the Abelson murine leukemia virus tyrosine-specific protein kinase into Xenopus oocytes. (1985) (52)
- A Constitutively Active Form of the Protein Kinase p90Rsk1 Is Sufficient to Trigger the G2/M Transition in Xenopus Oocytes* (2001) (51)
- The Anaphase-promoting Complex/Cyclosome Inhibitor Emi2 Is Essential for Meiotic but Not Mitotic Cell Cycles* (2006) (51)
- DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase. (1999) (49)
- In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase. (1978) (49)
- Ordered multisite phosphorylation of Xenopus ribosomal protein S6 by S6 kinase II. (1992) (49)
- Activation of a ribosomal protein S6 protein kinase in Xenopus oocytes by insulin and insulin‐receptor kinase. (1986) (48)
- p70S6K Controls Selective mRNA Translation during Oocyte Maturation and Early Embryogenesis inXenopus laevis (1999) (47)
- Identification of a Polo-like Kinase 4-Dependent Pathway for De Novo Centriole Formation (2011) (47)
- The mechanism of CSF arrest in vertebrate oocytes (2002) (47)
- A novel role for Greatwall kinase in recovery from DNA damage (2010) (46)
- Increased intracellular pH is not necessary for ribosomal protein s6 phosphorylation, increased protein synthesis, or germinal vesicle breakdown in Xenopus oocytes. (1985) (46)
- Ha-rasVal-12,Thr-59 activates S6 kinase and p34cdc2 kinase in Xenopus oocytes: evidence for c-mosxe-dependent and -independent pathways (1990) (45)
- Biochemical characterization of the p34cdc2 protein kinase component of purified maturation-promoting factor from Xenopus eggs. (1989) (44)
- Two-dimensional polyacrylamide gel analysis of changes in protein phosphorylation during maturation of Xenopus oocytes. (1985) (44)
- The Aurora A and Aurora B Protein Kinases: A Single Amino Acid Difference Controls Intrinsic Activity and Activation by TPX2 (2005) (43)
- Substrate specificity of ribosomal protein S6 kinase II from Xenopus eggs. (1988) (41)
- Fishing at the Cell Surface (2003) (41)
- The development of competence for meiotic maturation during oogenesis in Xenopus laevis. (1983) (39)
- Regulation of the G2/M Transition in Xenopus Oocytes by the cAMP-dependent Protein Kinase* (2005) (38)
- Role for cyclin A in the dependence of mitosis on: Nature 354, 314–317 (1992) (38)
- Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A (2009) (38)
- In vivo actions of protein phosphatase inhibitor‐2 in Xenopus oocytes (1982) (37)
- Inhibition of Xenopus oocyte adenylate cyclase by progesterone: a novel mechanism of action. (1985) (37)
- Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding (2010) (35)
- Antibodies to the ras gene product inhibit adenylate cyclase and accelerate progesterone-induced cell division in Xenopus laevis oocytes (1986) (35)
- Purification and characterization of a mitogen-activated protein kinase tyrosine phosphatase from Xenopus eggs. (1993) (34)
- Metaphase Arrest by Cyclin E-Cdk2 Requires the Spindle-Checkpoint Kinase Mps1 (2006) (32)
- Activation of p90Rsk1 Is Sufficient for Differentiation of PC12 Cells (2004) (31)
- A Role for G1/S Cyclin-dependent Protein Kinases in the Apoptotic Response to Ionizing Radiation* (2002) (31)
- Purification and characterization of ribosomal protein S6 kinase I from Xenopus eggs. (1991) (30)
- The Polo Box Is Required for Multiple Functions of Plx1 in Mitosis* (2004) (30)
- Xenopus Polo-like kinase Plx1: a multifunctional mitotic kinase (2005) (30)
- A Feedback Loop in the Polo-like Kinase Activation Pathway* (2004) (29)
- OOcyte maturation in amphibians. (1985) (29)
- Developmental regulation of MCM replication factors in Xenopus laevis (1998) (28)
- Phosphorylation of p53 Is Regulated by TPX2-Aurora A in Xenopus Oocytes*S⃞ (2009) (28)
- Regulation of Greatwall kinase during Xenopus oocyte maturation (2011) (28)
- New insight into metaphase arrest by cytostatic factor: from establishment to release (2007) (28)
- p70 S6K Controls Selective mRNA Translation during Oocyte Maturation and Early Embryogenesis in Xenopus laevis (1999) (27)
- The pathway of MAP kinase mediation of CSF arrest in Xenopus oocytes (2001) (26)
- Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. (2004) (26)
- Histone 1 phosphotransferase activities during the maturation of oocytes of Xenopus laevis. (1979) (25)
- Cell cycle transitions in early Xenopus development. (2001) (24)
- Transforming ras proteins accelerate hormone-induced maturation and stimulate cyclic AMP phosphodiesterase in Xenopus oocytes (1990) (24)
- Biochemistry of cell cycle checkpoints at the G2/M and metaphase/anaphase transitions (1994) (23)
- Undamaged DNA Transmits and Enhances DNA Damage Checkpoint Signals in Early Embryos (2007) (22)
- 3 – Regulation of Nuclear Formation and Breakdown in Cell-Free Extracts of Amphibian Eggs (1987) (22)
- The Polo-like Kinase Plx 1 Is Required for Activation of the Phosphatase Cdc 25 C and Cyclin B-Cdc 2 in Xenopus Oocytes (2001) (22)
- Regulating the Regulators: Aurora A Activation and Mitosis (2003) (21)
- A purified S6 kinase kinase from Xenopus eggs activates S6 kinase II and autophosphorylates on serine, threonine, and tyrosine residues. (1992) (20)
- Identification of protein phosphatases 1 and 2B as ribosomal protein S6 phosphatases in vitro and in vivo. (1987) (20)
- MPF and cell cycle control. (1990) (19)
- Signal transduction. Fishing at the cell surface. (2003) (19)
- DNA damage signaling in early Xenopus embryos (2008) (18)
- Post-transcriptional regulation by insulin of Xenopus ribosomal protein S6 kinase. (1988) (18)
- Reversibility of phosphorylase kinase reaction. (1977) (17)
- Kicking off the polo game. (2008) (16)
- Regulation of the G(2)/M transition in Xenopus oocytes by the cAMP-dependent protein kinase. (2005) (15)
- Purification and characterization of a novel protein phosphatase highly specific for ribosomal protein S6. (1989) (15)
- Reconstitution of p21ras-dependent and -independent mitogen-activated protein kinase activation in a cell-free system. (1993) (15)
- Phosphorylation of the Oxytricha telomere protein: possible cell cycle regulation. (1995) (14)
- Use of microinjection techniques to study protein kinases and protein phosphorylation in amphibian oocytes. (1983) (12)
- Phosphorylation and protein synthetic events in Xenopus laevis oocytes microinjected with pp60v-src (1985) (12)
- Regulation of the Aurora B Chromosome Passenger Protein Complex during Oocyte Maturation in Xenopus laevis (2008) (11)
- Centrosomal localization of cyclins E and A (2011) (11)
- Maturation-promoting factor in the early days. (1995) (11)
- Induction of metaphase chromosome condensation in human sperm by Xenopus egg extracts. (1988) (11)
- Cloning and expression of a Xenopus gene that prevents mitotic catastrophe in fission yeast (1995) (10)
- Mitogenic signalling and protein phosphorylation in Xenopus oocytes. (1986) (9)
- On the importance of protein phosphorylation in cell cycle control (1993) (9)
- Identification of a Xenopus cDNA that prevents mitotic catastrophe in the fission yeast Schizosaccharomyces pombe. (1994) (8)
- Cell multiplication. (1993) (8)
- Xenopus ribosomal protein S6 kinase II. (1991) (8)
- Growth factor-activated kinases phosphorylate IRE-ABP. (1992) (8)
- Identification of an activator required for elevation of maturation- promoting factor (MPF) activity by gamma-S-ATP (1990) (8)
- [21] Xenopus ribosomal protein S6 kinase II (1991) (8)
- Pioneering the Xenopus Oocyte and Egg Extract System (2012) (7)
- Molecular analyses of gene products associated with the response of cells to mitogenic stimulation. (1988) (7)
- Oocyte maturation in amphibians and the regulation of meiosis and mitosis. (1988) (5)
- Protein Phosphorylation and the Regulation of Key Events in Oocyte and Egg Cell Cycles (1994) (3)
- A protein kinase from Xenopus eggs specific for ribosomal protein S 6 ( ribosomal protein S 6 protein kinase / growth control / S 6 phosphopeptide mapping (3)
- A Similar Pool of Cyclic AMP Phosphodiesterase in Xenopus Oocytes Is Stimulated by Insulin , Insulin-like Growth Factor 1 , and [ Va 112 , Thr 69 ] (2001) (2)
- Cell cycle and mitotic control in Xenopus eggs. (1991) (1)
- Control of Cell Division by Protein Phosphorylation (1979) (1)
- Recurring themes in oocyte maturation (1998) (1)
- Phosphorylation of ribosomal protein S 6 on serine after microinjection of the Abelson murine leukemia virus tyrosine-specific protein kinase into Xenopus oocytes ( tyrosyl-protein kinases / growth control ) (1)
- Regulating the G2 Checkpoint in the Cell Cycle (1993) (0)
- Differentiation of PC12 Cells Is Sufficient for Rsk1 Activation of p90 (2014) (0)
- THE APC/C INHIBITOR EMI2 IS ESSENTIAL FOR MEIOTIC BUT NOT MITOTIC CELL CYCLES (2006) (0)
- Spindle Pole Regulation by a Discrete X2 (0)
- A Role for G 1 / S Cyclin-dependent Protein Kinases in the Apoptotic Response to Ionizing Radiation * (2002) (0)
- Phosphorylation andProtein Synthetic EventsinXenopuslaevis Oocytes Microinjected withpp6OV-src (1985) (0)
- PIONEERING THE XENOPUS OOCYTE AND EGG SYSTEM ” (2012) (0)
- Introductory Editorial Oocyte maturation and cell cycle control (2004) (0)
- In vivo phosphorylation of a synth( AMP-dependent protein kinase (Xenopus oocytes/microinjection/protein phosphorylation/pept (2016) (0)
- Cell multiplication. (1996) (0)
- Interaction of steroids and growth factors with the plasma membrane in the induction of oocyte maturation in Xenopus laevis. (1982) (0)
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