Jens Lykkesfeldt
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Jens Lykkesfeldt's Degrees
- PhD Medical Sciences University of Copenhagen
- Masters Biochemistry University of Copenhagen
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(Suggest an Edit or Addition)Jens Lykkesfeldt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Oxidants and antioxidants in disease: oxidative stress in farm animals. (2007) (662)
- Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease (2018) (560)
- Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking. (2007) (383)
- Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress (2002) (335)
- (R)‐α‐Lipoic acid‐supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate (1999) (288)
- Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. (1998) (278)
- Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies. (2018) (272)
- In vivo toxicity of cationic micelles and liposomes. (2015) (258)
- Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry. (2001) (235)
- Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. (2000) (233)
- Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride. (2000) (219)
- Antioxidant supplementation does not alter endurance training adaptation. (2010) (183)
- Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection--are they reliable biomarkers of oxidative stress? (1995) (175)
- BCPT policy for experimental and clinical studies (2020) (165)
- Age‐associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes—reversal with (R)‐α‐lipoic acid supplementation (1998) (162)
- Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking. (1997) (161)
- Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials (2009) (155)
- Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. (1995) (149)
- The Pharmacokinetics of Vitamin C (2019) (143)
- Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men. (2004) (139)
- Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation. (2002) (130)
- Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans? (2012) (130)
- (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. (1999) (112)
- Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion. (1998) (105)
- Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation. (2005) (104)
- Regulation of Vitamin C Homeostasis during Deficiency (2013) (103)
- Artemisinin induces omeprazole metabolism in human beings (1998) (94)
- Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability (2018) (93)
- Vitamin C supplementation decreases oxidative DNA damage in mononuclear blood cells of smokers (2004) (93)
- The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs. (2003) (85)
- Ascorbate and Dehydroascorbic Acid as Reliable Biomarkers of Oxidative Stress: Analytical Reproducibility and Long-term Stability of Plasma Samples Subjected to Acidic Deproteinization (2007) (81)
- A role of peroxisome proliferator‐activated receptor γ in non‐alcoholic fatty liver disease (2019) (80)
- Vitamin C. (2014) (79)
- Effect of smoking cessation on plasma ascorbic acid concentration (1996) (79)
- Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training. (2011) (77)
- Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells. (2011) (77)
- Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs. (2009) (74)
- Increased systemic oxidatively generated DNA and RNA damage in schizophrenia (2013) (72)
- Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L. (1995) (69)
- Role of vitamin C and E supplementation on IL-6 in response to training. (2012) (68)
- Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle. (2007) (65)
- Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection. (2003) (64)
- Does Vitamin C Deficiency Affect Cognitive Development and Function? (2014) (63)
- Synthesis of Benzylglucosinolate in Tropaeolum majus L. (Isothiocyanates as Potent Enzyme Inhibitors) (1993) (61)
- Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial (2016) (61)
- Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment. (2001) (61)
- Maternal Vitamin C Deficiency during Pregnancy Persistently Impairs Hippocampal Neurogenesis in Offspring of Guinea Pigs (2012) (58)
- Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies. (2014) (58)
- Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain (2007) (57)
- Simultaneous determination of urinary free cortisol and 6 beta-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity. (1994) (57)
- Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations. (2002) (56)
- Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo. (2003) (56)
- Role of marginal vitamin C deficiency in atherogenesis: in vivo models and clinical studies. (2009) (55)
- Does Vitamin C Deficiency Promote Fatty Liver Disease Development? (2014) (55)
- Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives (2020) (53)
- Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague–Dawley rats (2018) (53)
- Antioxidant supplementation for lung disease in cystic fibrosis. (2014) (52)
- Utility of melatonin to treat surgical stress after major vascular surgery – a safety study (2008) (52)
- Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults (2015) (50)
- Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model. (2014) (50)
- Elimination of Ascorbic Acid After High‐Dose Infusion in Prostate Cancer Patients: A Pharmacokinetic Evaluation (2015) (48)
- Whey Protein Reduces Early Life Weight Gain in Mice Fed a High-Fat Diet (2013) (48)
- Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles (2004) (46)
- Increased Oxidative Damage in Vitamin C Deficiency is Accompanied by Induction of Ascorbic Acid Recycling Capacity in Young But Not Mature Guinea Pigs (2002) (44)
- Cerebral Vasculature Is the Major Target of Oxidative Protein Alterations in Bacterial Meningitis (2002) (42)
- Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used. (2012) (41)
- Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs. (2017) (41)
- A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®) (2012) (40)
- Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice (2016) (40)
- In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines. (2016) (40)
- Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone (2004) (39)
- Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes (2019) (39)
- Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non‐Alcoholic Steatohepatitis (2018) (39)
- Age-dependent change in Vitamin C status: A phenomenon of maturation rather than of ageing (2005) (38)
- Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs. (2015) (37)
- Measurement of Ascorbic Acid and Dehydroascorbic Acid in Biological Samples (2002) (37)
- Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs. (2016) (37)
- Normal weight dyslipidemia: Is it all about the liver? (2016) (36)
- On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence (2020) (35)
- Differential toxicological response to positively and negatively charged nanoparticles in the rat brain (2013) (34)
- Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice. (2016) (33)
- Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research. (2016) (33)
- Does vitamin C deficiency result in impaired brain development in infants? (2009) (33)
- Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats (2014) (32)
- High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs (2010) (32)
- Dyslipidemia: Obese or Not Obese—That Is Not the Question (2016) (31)
- Does vitamin C deficiency increase lifestyle-associated vascular disease progression? Evidence based on experimental and clinical studies. (2013) (30)
- Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: a single-arm phase II trial (2017) (30)
- Pronounced Inflammatory Response to Endotoxaemia during Nighttime: A Randomised Cross-Over Trial (2014) (30)
- No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial. (2010) (30)
- Effect of Insulin‐Induced Hypoglycaemia on the Central Nervous System: Evidence from Experimental Studies (2014) (29)
- Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components (2011) (28)
- Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs. (2003) (28)
- Ampicillin-Improved Glucose Tolerance in Diet-Induced Obese C57BL/6NTac Mice Is Age Dependent (2013) (28)
- The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study. (2015) (27)
- Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes. (2009) (27)
- High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs (2016) (27)
- Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals (2015) (26)
- 2-nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. (1991) (26)
- No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo‐controlled trial (2010) (25)
- Endothelial dysfunction in the early postoperative period after major colon cancer surgery (2017) (25)
- Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles. (2019) (25)
- l-dehydroascorbic acid can substitute l-ascorbic acid as dietary vitamin C source in guinea pigs (2015) (25)
- Effect of Insulin‐Induced Hypoglycaemia on the Peripheral Nervous System: Focus on Adaptive Mechanisms, Pathogenesis and Histopathological Changes (2014) (24)
- Cyanogenic glycosides in cassava, Manihot esculenta crantz (1994) (24)
- Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains (2014) (23)
- Vitamin C pharmacokinetics of plain and slow release formulations in smokers. (2004) (23)
- Chronic Vitamin C Deficiency does not Accelerate Oxidative Stress in Ageing Brains of Guinea Pigs (2012) (23)
- Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo. (2013) (23)
- Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs. (2003) (22)
- Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture. (2010) (22)
- Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice (2020) (21)
- Electroencephalographic Changes after Pediatric Cardiac Surgery with Cardiopulmonary Bypass: Is Slow Wave Activity Unfavorable? (2005) (21)
- Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics (2018) (21)
- Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies (2016) (21)
- Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers (2015) (21)
- Smoking Depletes Vitamin C: Should Smokers Be Recommended to Take Supplements? (2006) (20)
- Non-terminal blood sampling techniques in guinea pigs. (2014) (20)
- Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey (2016) (20)
- Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease? (2020) (19)
- Poor Vitamin C Status Late in Pregnancy Is Associated with Increased Risk of Complications in Type 1 Diabetic Women: A Cross-Sectional Study (2017) (19)
- Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors (2014) (19)
- Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs (2015) (19)
- Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs (2013) (19)
- Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration (2017) (19)
- Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs. (2001) (18)
- Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats. (2012) (17)
- Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models. (2019) (17)
- Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin (2013) (17)
- Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia (2015) (14)
- Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles (2018) (14)
- In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain. (2014) (14)
- Determination of Reduced and Oxidized Coenzyme Q10 in Canine Plasma and Heart Tissue by HPLC-ECD: Comparison with LC-MS/MS Quantification (2019) (14)
- Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea. (2004) (13)
- Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in guinea pigs. (2012) (13)
- Oxidative stress and damage in liver, but not in brain, of fischer 344 rats subjected to dietary iron supplementation with lipid‐soluble [(3,5,5‐trimethylhexanoyl)ferrocene] (2007) (13)
- Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age. (1999) (13)
- Atorvastatin and Vitamin E Accelerates NASH Resolution by Dietary Intervention in a Preclinical Guinea Pig Model (2019) (12)
- Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain. (2016) (12)
- Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model (2019) (12)
- Issue Information ‐ Table of Contents (2016) (12)
- Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance (2016) (12)
- Long term Westernized diet leads to region-specific changes in brain signaling mechanisms (2018) (12)
- Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction. (2014) (11)
- Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function (2013) (11)
- Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study. (2017) (11)
- Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide. (2018) (11)
- The role of vitamin C in epigenetic cancer therapy. (2021) (10)
- Effect of smoking on erythorbic acid pharmacokinetics. (2003) (10)
- Endothelial dysfunction and myocardial injury after major emergency abdominal surgery: a prospective cohort study (2020) (10)
- A convenient synthesis of homochiral δ-alkylated α,β-unsaturated δ-lactones (1991) (9)
- The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial (2019) (9)
- Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat. (2018) (9)
- Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD (2018) (9)
- Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4 (2006) (9)
- Chronic Vitamin C Deficiency Promotes Redox Imbalance in the Brain but Does Not Alter Sodium-Dependent Vitamin C Transporter 2 Expression (2014) (8)
- Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure (2011) (8)
- Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain (2017) (8)
- Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study. (2014) (8)
- Antioxidant supplementation for lung disease in cystic fibrosis. (2019) (8)
- Liraglutide treatment improves endothelial function in the Ldlr−/− mouse model of atherosclerosis and affects genes involved in vascular remodelling and inflammation (2020) (8)
- Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials (2017) (8)
- Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity (2018) (7)
- Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study (2019) (7)
- Translational aspects of rectal evoked potentials: a comparative study in rats and humans. (2013) (7)
- Translational aspects of rectal evoked potentials: A comparative study in rats and humans (2012) (7)
- Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case–control study (2015) (7)
- Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method (2019) (7)
- The kidneys play a central role in the clearance of rhGH in rats. (2016) (6)
- Malnutrition Predisposes to Endotoxin-Induced Edema and Impaired Inflammatory Response in Parenterally Fed Piglets. (2020) (6)
- Prolonged effect of a new O‐glycoPEGylated FVIII (N8‐GP) in a murine saphenous vein bleeding model (2013) (6)
- Animal Models in Pharmacology and Toxicology (2011) (6)
- Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation (2020) (6)
- Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model (2018) (6)
- Vitamin C Deficiency Reduces Muscarinic Receptor Coronary Artery Vasoconstriction and Plasma Tetrahydrobiopterin Concentration in Guinea Pigs (2017) (6)
- Toxicological Effects during and following Persistent Insulin‐Induced Hypoglycaemia in Healthy Euglycaemic Rats (2017) (6)
- Brief Communication: Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice (2017) (6)
- The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non‐alcoholic steatohepatitis (2020) (6)
- Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs (2014) (6)
- Pharmacological modulation of colorectal distension evoked potentials in conscious rats (2018) (5)
- On the Absence of 2-(2'-Cyclopentenyl)glycine-Derived Cyanogenic Glycosides in Cassava, Manihot esculenta Crantz. (1995) (5)
- Ascorbate maintains a low plasma oxygen level (2020) (5)
- Positive charge, negative effect: the impact of cationic nanoparticles in the brain. (2014) (5)
- Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation (2018) (5)
- Estimation of Vitamin C Intake Requirements Based on Body Weight: Implications for Obesity (2022) (5)
- Effect of High Inspiratory Oxygen Fraction on Endothelial Function in Healthy Volunteers: A Randomized Controlled Crossover Pilot Study (2017) (5)
- Thick Methacrylate Sections Devoid of Lost Caps Simplify Stereological Quantifications Based on the Optical Fractionator Design (2015) (5)
- Morphine reduces spinal c-fos expression dose-dependently during experimental laparotomy in pigs: a combined pharmacokinetic and surgical study. (2008) (5)
- Differential Effects of Dietary Components on Glucose Intolerance and Non-Alcoholic Steatohepatitis (2021) (4)
- Temporal Development of Dyslipidemia and Nonalcoholic Fatty Liver Disease (NAFLD) in Syrian Hamsters Fed a High-Fat, High-Fructose, High-Cholesterol Diet (2021) (4)
- High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice (2014) (4)
- The kidneys play an important role in the clearance of rFVIIa in rats. (2014) (4)
- Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics. (2013) (4)
- Role of Antioxidant Supplementation on Training-induced Il-6 (2010) (4)
- Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease (2020) (4)
- Importance of gestational hypoglycaemia for foetal malformations and skeletal development in rats. (2019) (4)
- Oxidative Stress Response After Laparoscopic Versus Conventional Sigmoid Resection: A Randomized, Double-blind Clinical Trial (2012) (4)
- Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model (2021) (4)
- A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats (2021) (4)
- Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia. (2005) (4)
- Vitamin C: From Bench to Bedside (2021) (4)
- The counterregulatory response to hypoglycaemia in the pig (2020) (3)
- Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE−/− mice (2021) (3)
- Vitamin C Pharmacokinetics * (2020) (3)
- Vitamin C and Its Role in Brain Development and Cognition (2012) (3)
- An ELISA for detection of complement-bound circulating immune complexes in mice (2019) (3)
- Vitamin C in Health and Disease (2017) (3)
- The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs (2021) (3)
- Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4. (2006) (3)
- Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers (2019) (3)
- Glycemic Control during Pregnancy—A Predictor of Vitamin C Status at Labor in Type 1 Diabetic Women? (2019) (3)
- Maternal vitamin C deficiency does not reduce hippocampal volume and β-tubulin III intensity in prenatal Guinea pigs. (2016) (3)
- A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis. (2019) (3)
- Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig (2021) (2)
- Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats (2018) (2)
- Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat. (2018) (2)
- Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels (2021) (2)
- Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG. (2019) (2)
- Depleted Myocardial Coenzyme Q10 in Cavalier King Charles Spaniels with Congestive Heart Failure Due to Myxomatous Mitral Valve Disease (2021) (2)
- Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs (2022) (2)
- Long-term high copper intake : effects on indexes of copper status , antioxidant status , and immune function in young men 1 – 3 (2004) (2)
- Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner (2018) (1)
- Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs (2021) (1)
- Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes (2020) (1)
- Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis (2022) (1)
- Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease (2018) (1)
- The ascorbate-deficient guinea pig model of shigellosis allows the study of the entire Shigella life cycle (2020) (1)
- Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017–2018 (2023) (1)
- Ascorbinsyre er lavere hos garvide med type 1 diabetes sammenlignet med kontrol kvinder: Et prospektivt studie ; Ascorbic acid is lower during pregnancy in diabetic women compared to controls: A prospective study (2016) (1)
- Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD (2021) (1)
- Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats (2020) (1)
- Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles (2018) (1)
- High-fat feeding induces mobilization of vitamin C in obese prone rats. (2018) (1)
- Erratum to: Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs (2015) (1)
- Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing (2017) (0)
- response to training Role of vitamin C and E supplementation on IL-6 in (2015) (0)
- 240 - Increased Oxidative Stress in Dyslipidemic Guinea Pigs with Fatty Liver Disease (2014) (0)
- Ascorbate maintains a low plasma oxygen level (2020) (0)
- Professor Christian Friis: An appreciation. (2021) (0)
- [Nitrosamine formation via non-prescription drugs?]. (1993) (0)
- Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet (2016) (0)
- Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes (2019) (0)
- Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet (2022) (0)
- University of Southern Denmark Weekly ascorbic acid infusion in castration-resistant prostate cancer patients A single-arm phase II trial (2017) (0)
- 113 – Vitamin C Enhances Endothelin B Receptor Mediated Vascular Contractile Function in Guinea Pig Arteries (2015) (0)
- Vitamin C transporters in the guinea pig placenta (2013) (0)
- involved in signal transduction and glucose transport Exercise-associated differences in an array of proteins (2015) (0)
- Ascorbate maintains a low plasma low oxygen level (2020) (0)
- Elimination of Ascorbic Acid following High-Dose Infusion in Prostate Cancer Patients : A Pharmacokinetic Evaluation (2014) (0)
- 18 Validation of Flow Cytometry-Based Quantitation of Reticulated Platelets in Cynomolgus Monkeys and Wistar Rats (2018) (0)
- Vitamin C Homeostasis in the Guinea Pig Brain (2012) (0)
- The Oxidant and Antioxidant Functions of Estrogens (1994) (0)
- Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation (2022) (0)
- PSS247 - Maternal Vitamin C Deficiency Depletes the Fetus and Does Not Modulate SVCT1 and 2 Expression in the Guinea Pig Placenta (2013) (0)
- Evaluation of the moderately obese apoe gene knockout rat as a new model for impaired glucose tolerance and atherosclerosis (2014) (0)
- 141 - High-Dose Ascorbic Acid in Metastatic Castration-Resistant Prostate Cancer: Evaluation of Efficacy and Safety in a Phase II Trial. (2015) (0)
- Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults (2015) (0)
- Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton (2018) (0)
- Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease (2021) (0)
- Prolonged Vitamin C Deficiency Leads to Tetrahydrobiopterin Oxidation in Vivo (2012) (0)
- Changing dietary content of gluten–and potentially the gut microbiota, did not result in increased atherosclerosis in the apoe-/-mouse (2014) (0)
- 178 - High-Fat But Not Sucrose Is Essential for Induction of Non-Alcoholic Steatohepatitis and Fibrosis (2015) (0)
- Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs (2022) (0)
- Optimized treatment regimens for enrofloxacin in pigs limits selection for resistance in salmonella and coliforms (2004) (0)
- Vitamin C and oxidative damage to DNA: chapter 11 (2004) (0)
- Low Levels of Vitamin C Increases Oxidative Stress but Does Not Alter Sodium-Dependent Vitamin C Transporter, SVCT2, Expression in the Brain (2012) (0)
- A Convenient Synthesis of Homochiral δ-Alkylated α,β- Unsaturated δ-Lactones. (1991) (0)
- Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat. (2020) (0)
- Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations (2023) (0)
- DIABETES RESULTS IN OXIDATIVE STRESS DIRVEN PLAQUE FORMATION IN THE APO E KNOCKOUT MOUSE (2016) (0)
- Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity (2019) (0)
- Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes (2020) (0)
- The Effect of Supplemental Ascorbate on Defersirox Iron Chelation In the Iron-Loaded Gerbil (2010) (0)
- Prenatal Vitamin C Deficiency in Guinea Pigs Leads To Slower Dentate Granule Migration and Sustained Volume Reduction of the Postnatal Hippocampus (2011) (0)
- Title : Simultaneous quanti fi cation of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain (2016) (0)
- Oxidative DNA modification, plasma ascorbate and smoking (1997) (0)
- Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs (2014) (0)
- Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial (2023) (0)
- Letter to the Editor Reply to Hemilä by Lykkesfeldt and Poulsen (2010) (0)
- Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics (2018) (0)
- Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats (2022) (0)
- Effect of mild streptozotocin/nicotinamide-induced diabetes on aortic plaque area in new minipig model of atherosclerosis (2014) (0)
- Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals (2015) (0)
- F156 REPRODUCIBILITY OF A NEW MODEL USING EVOKED POTENTIALS AS RESPONSE TO MECHANICAL COLORECTAL DISTENSION (2011) (0)
- Maternal Vitamin C Deficiency Impairs Normal Fetal Ascorbate Influx But Does Not Influence Perinatal Survival in Guinea Pigs (2012) (0)
- Comparison of Two Animal Models for Evaluation of Defersirox Iron Chelation (2010) (0)
- Chronic dyslipidemia induces fatty liver disease in Guinea pigs (2015) (0)
- Amoxicillin Plasma Concentrations After per Oral Application in Newly Weaned Pigs – Effects of Escherichia coli O149,F4 Associated Diarrhoea (2003) (0)
- A longterm energyrich diet increases prefrontal bdnf in spraguedawley rats (2021) (0)
- Formation and Glomerular Deposition of Immune Complexes in Mice Administered Human Antibodies: Evaluation of Dose, Frequency, and Biomarkers (2020) (0)
- NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model (2022) (0)
- exercise in humans Antioxidants attenuate the plasma cytokine response to (2015) (0)
- Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs. (2019) (0)
- Feeding acetyl-L-carnitine ant significantly improves metab decreasing oxidative stress (2016) (0)
- Reply to Hemilä by Lykkesfeldt and Poulsen (2010) (0)
- Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats (2020) (0)
- Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD (2021) (0)
- The dietary regulation of LEAP2 depends on meal composition in mice. (2023) (0)
- Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model (2019) (0)
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