John M. Dietschy
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Biology
John M. Dietschy's Degrees
- Masters Molecular Biology Stanford University
Why Is John M. Dietschy Influential?
(Suggest an Edit or Addition)John M. Dietschy's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. (2000) (1317)
- Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal Published, JLR Papers in Press, May 16, 2004. DOI 10.1194/jlr.R400004-JLR200 (2004) (867)
- Cholesterol metabolism in the brain (2001) (863)
- Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. (1993) (860)
- Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile. (1978) (500)
- Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat. (1983) (396)
- Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1−/− mouse (2009) (367)
- Knockout of the Cholesterol 24-Hydroxylase Gene in Mice Reveals a Brain-specific Mechanism of Cholesterol Turnover* (2003) (362)
- Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster. (1988) (347)
- Relative importance of high and low density lipoproteins in the regulation of cholesterol synthesis in the adrenal gland, ovary, and testis of the rat. (1978) (344)
- The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. (1976) (322)
- Regulation of cholesterol metabolism. (1970) (306)
- Dietary saturated triacylglycerols suppress hepatic low density lipoprotein receptor activity in the hamster. (1985) (280)
- Control of Cholesterol Turnover in the Mouse* (2002) (274)
- Central nervous system: cholesterol turnover, brain development and neurodegeneration (2009) (272)
- Regulation of plasma LDL-cholesterol levels by dietary cholesterol and fatty acids. (1993) (270)
- Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states. (1979) (267)
- Delineation of the dimensions and permeability characteristics of the two major diffusion barriers to passive mucosal uptake in the rabbit intestine. (1974) (266)
- Mechanisms for the intestinal absorption of bile acids. (1968) (262)
- Effect of cholesterol feeding and fasting on sterol synthesis in seventeen tissues of the rat. (1967) (254)
- Regulation of cholesterol metabolism. I. (1970) (253)
- Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia. (1998) (253)
- Characterization of the kinetics of the passive and active transport mechanisms for bile acid absorption in the small intestine and colon of the rat. (1972) (253)
- Disturbances in lipid and lipoprotein metabolism (1978) (238)
- Saturated and unsaturated fatty acids independently regulate low density lipoprotein receptor activity and production rate. (1992) (228)
- The intestinal unstirred layer: its surface area and effect on active transport kinetics. (1974) (223)
- Rates of receptor-dependent and -independent low density lipoprotein uptake in the hamster. (1983) (212)
- Regulation of rates of cholesterol synthesis in vivo in the liver and carcass of the rat measured using [3H]water. (1980) (209)
- Dietary fatty acids and the regulation of plasma low density lipoprotein cholesterol concentrations. (1998) (206)
- Cholesterol synthesis by the gastrointestinal tract: localization and mechanisms of control. (1965) (201)
- Cholesterol synthesis in the squirrel monkey: relative rates of synthesis in various tissues and mechanisms of control. (1968) (194)
- Rates of sterol synthesis and uptake in the major organs of the rat in vivo. (1981) (192)
- Measurement of rates of cholesterol synthesis using tritiated water. (1984) (191)
- Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse. (1995) (188)
- Rates of low density lipoprotein uptake and cholesterol synthesis are regulated independently in the liver. (1985) (187)
- Disruption of the Sterol 27-Hydroxylase Gene in Mice Results in Hepatomegaly and Hypertriglyceridemia (2000) (186)
- Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid (2010) (169)
- Regulation of sterol synthesis in 15 tissues of rat. II. Role of rat and human high and low density plasma lipoproteins and of rat chylomicron remnants. (1977) (168)
- Neurodegeneration in the Niemann–Pick C mouse: glial involvement (2002) (165)
- Unstirred Water Layers in Intestine: Rate Determinant of Fatty Acid Absorption from Micellar Solutions (1971) (164)
- The role of bile salts in controlling the rate of intestinal cholesterogenesis. (1968) (164)
- Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration Published, JLR Papers in Press, June 16, 2003. DOI 10.1194/jlr.M300164-JLR200 (2003) (161)
- Bile acid metabolism. I. Studies on the mechanisms of intestinal transport. (1966) (160)
- Sterol absorption by the small intestine (2003) (159)
- Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse. (2003) (159)
- Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver. (1978) (154)
- Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: human and animal studies. (1997) (154)
- Failure of bile acids to control hepatic cholesterogenesis: evidence for endogenous cholesterol feedback. (1969) (152)
- Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding. (2001) (148)
- Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life (2010) (146)
- Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. (1994) (145)
- Absolute rates of cholesterol synthesis in extrahepatic tissues measured with 3H-labeled water and 14C-labeled substrates. (1979) (144)
- Unstirred water layers and absorption across the intestinal mucosa. (1971) (143)
- Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 Mouse (2007) (138)
- Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and Is Prevented by Driving Cholesterol Export from This Compartment (2011) (137)
- Fatty acids regulate hepatic low density lipoprotein receptor activity through redistribution of intracellular cholesterol pools. (1992) (134)
- Determinants of intestinal mucosal uptake of short- and medium-chain fatty acids and alcohols. (1973) (131)
- Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis. (1974) (131)
- Biological activity, lipoprotein-binding behavior, and in vivo disposition of extracted and native forms of Salmonella typhimurium lipopolysaccharides. (1982) (129)
- Characterization of bile acid absorption across the unstirred water layer and brush border of the rat jejunum. (1972) (125)
- Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster. (1992) (125)
- Cholesterol accumulation and liver cell death in mice with Niemann‐Pick type C disease (2005) (120)
- ACAT2 deficiency limits cholesterol absorption in the cholesterol‐fed mouse: Impact on hepatic cholesterol homeostasis (2004) (119)
- Limitations of acetate as a substrate for measuring cholesterol synthesis in liver. (1974) (116)
- Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann‐Pick C disease (2001) (116)
- Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep. (1996) (114)
- Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease. (2005) (114)
- Determination of unidirectional uptake rates for lipids across the intestinal brush border. (1972) (113)
- Derivation of the equations that describe the effects of unstirred water layers on the kinetic parameters of active transport processes in the intestine. (1977) (112)
- Sterol synthesis and low density lipoprotein clearance in vivo in the pregnant rat, placenta, and fetus. Sources for tissue cholesterol during fetal development. (1988) (110)
- Cholesterol synthesis in the intestine of man: regional differences and control mechanisms. (1971) (109)
- Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration. (1998) (108)
- Regulation of biliary cholesterol output in the rat: dissociation from the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, and the hepatic uptake of chylomicron cholesterol. (1979) (107)
- Cholesterol Is Sequestered in the Brains of Mice with Niemann‐Pick Type C Disease but Turnover Is Increased (2000) (106)
- Receptor-independent low density lipoprotein transport in the rat in vivo. Quantitation, characterization, and metabolic consequences. (1985) (105)
- Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver. (1994) (103)
- Kinetic constants for receptor-dependent and receptor-independent low density lipoprotein transport in the tissues of the rat and hamster. (1986) (103)
- Correlation of low and high density lipoprotein binding in vivo with rates of lipoprotein degradation in the rat. A comparison of lipoproteins of rat and human origin. (1982) (102)
- Gender‐related differences in bile acid and sterol metabolism in outbred CD‐1 mice fed low‐ and high‐cholesterol diets (1998) (102)
- Cholesterol-lowering action of psyllium mucilloid in the hamster: sites and possible mechanisms of action. (1991) (101)
- 3-Hydroxy-3-methylglutaryl coenzyme A reductase. Solubilization and purification of a cold-sensitive microsomal enzyme. (1973) (100)
- Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ. (1999) (98)
- The contribution of newly synthesized cholesterol to biliary cholesterol in the rat. (1981) (97)
- Validation of a chamber that allows measurement of both tissue uptake rates and unstirred layer thicknesses in the intestine under conditions of controlled stirring. (1974) (97)
- Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors. (1983) (96)
- Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein. (1999) (95)
- Binding of Salmonella typhimurium lipopolysaccharides to rat high-density lipoproteins (1981) (93)
- Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400475-JLR200 (2005) (92)
- Water and electrolyte movement in the intestine. (1966) (91)
- Mechanisms by which saturated triacylglycerols elevate the plasma low density lipoprotein-cholesterol concentration in hamsters. Differential effects of fatty acid chain length. (1989) (91)
- Sites of tissue binding and uptake in vivo of bacterial lipopolysaccharide-high density lipoprotein complexes: studies in the rat and squirrel monkey. (1981) (91)
- Genetic variations and treatments that affect the lifespan of the NPC1 mouse Published, JLR Papers in Press, December 12, 2007. (2008) (90)
- Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200144-JLR200 (2002) (85)
- Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma. (1996) (85)
- Effects of bile salts on intermediate metabolism of the intestinal mucosa. (1967) (81)
- Regulation of sterol synthesis in 16 tissues of rat. I. Effect of diurnal light cycling, fasting, stress, manipulation of enterohepatic circulation, and administration of chylomicrons and triton. (1977) (78)
- Role of receptor-independent low density lipoprotein transport in the maintenance of tissue cholesterol balance in the normal and WHHL rabbit. (1987) (76)
- Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver. (1986) (75)
- Theoretical considerations of what regulates low-density-lipoprotein and high-density-lipoprotein cholesterol. (1997) (74)
- Is there a connection between the concentration of cholesterol circulating in plasma and the rate of neuritic plaque formation in Alzheimer disease? (2000) (74)
- Role of liver in the synthesis of cholesterol and the clearance of low density lipoproteins in the cynomolgus monkey. (1995) (72)
- Ability of six different lipoprotein fractions to regulate the rate of hepatic cholesterogenesis in vivo. (1975) (72)
- Alteration of the degree of biliary cholesterol saturation in the hamster and rat by manipulation of the pools of preformed and newly synthesized cholesterol. (1983) (69)
- Cholesterol synthesis and low density lipoprotein uptake are regulated independently in rat small intestinal epithelium. (1983) (69)
- WATER AND SOLUTE MOVEMENT ACROSS THE WALL OF THE EVERTED RABBIT GALL BLADDER. (1964) (69)
- The kinetic characteristics of inhibition of hepatic cholesterogenesis by lipoproteins of intestinal origin. (1975) (68)
- Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters. (2008) (66)
- Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations (2011) (64)
- Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs. (1998) (63)
- Regulation of cholesterol metabolism in man and in other species (1984) (62)
- Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease Published, JLR Papers in Press, January 14, 2007. (2007) (61)
- Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: effect on cholesterol responsiveness. (1999) (60)
- The Role of the Unstirred Water Layer in Intestinal Permeation (1984) (59)
- Dual modulation of hepatic and intestinal acyl‐CoA: cholesterol acyltransferase activity by (de‐)phosphorylation and substrate supply in vitro (1983) (57)
- Synthesis and coenzyme A-dependent esterification of cholesterol in rat intestinal epithelium. Differences in cellular localization and mechanisms of regulation. (1983) (55)
- The mechanisms of and the interrelationship between bile acid and chylomicron-mediated regulation of hepatic cholesterol synthesis in the liver of the rat. (1978) (54)
- Rates of cholesterol synthesis and low-density lipoprotein uptake in the adrenal glands of the rat, hamster and rabbit in vivo. (1985) (54)
- The Interaction of Dietary Cholesterol and Specific Fatty Acids in the Regulation of LDL Receptor Activity and Plasma LDL‐Cholesterol Concentrations a (1993) (52)
- Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. (1983) (52)
- Relative rates of sterol synthesis in the liver and various extrahepatic tissues of normal and cholesterol-fed rabbits. Relationship to plasma lipoprotein and tissue cholesterol levels. (1982) (51)
- Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1). (2000) (51)
- Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse. (1995) (51)
- Inappropriate hepatic cholesterol synthesis expands the cellular pool of sterol available for recruitment by bile acids in the rat. (1989) (50)
- Cholesterogenesis: derepression in extrahepatic tissues with 4-aminopyrazolo (3,4-d) pyrimidine. (1976) (49)
- Kinetic parameters of the lipoprotein transport systems in the adrenal gland of the rat determined in vivo. Comparison of low and high density lipoproteins of human and rat origin. (1981) (49)
- Effect of feeding psyllium and cholestyramine in combination on low density lipoprotein metabolism and fecal bile acid excretion in hamsters with dietary-induced hypercholesterolemia. (1996) (48)
- Bile salt metabolism (1969) (48)
- Trans-9-octadecenoic acid is biologically neutral and does not regulate the low density lipoprotein receptor as the cis isomer does in the hamster. (1994) (48)
- Differential diagnostic approach to clinical problems of malabsorption. (1971) (48)
- Effects of specific antibodies, hormones, and lipoproteins on bacterial lipopolysaccharides injected into the rat. (1985) (46)
- The intestinal absorption of biliary and dietary cholesterol as a drug target for lowering the plasma cholesterol level. (2003) (46)
- Regulation of sterol synthesis in adrenal gland of the rat by both high and low density human plasma lipoproteins. (1976) (46)
- NA AND K ACTIVITY COEFFICIENTS IN BILE AND BILE SALTS DETERMINED BY GLASS ELECTRODES. (1964) (46)
- Age-related decreases in tissue sterol acquisition are mediated by changes in cholesterol synthesis and not low density lipoprotein uptake in the rat. (1984) (45)
- Degeneration of neurons and glia in the Niemann–Pick C mouse is unrelated to the low-density lipoprotein receptor (2001) (44)
- Cholesterol substrate pools and steroid hormone levels are normal in the face of mutational inactivation of NPC1 protein Published, JLR Papers in Press, February 3, 2006. (2006) (43)
- Bile salt hydrophobicity influences cholesterol recruitment from rat liver in vivo when cholesterol synthesis and lipoprotein uptake are constant. (1988) (43)
- Identification of a metabolic difference accounting for the hyper- and hyporesponder phenotypes of cynomolgus monkey. (1997) (41)
- Quantitative importance of different organs for cholesterol synthesis and low-density-lipoprotein degradation. (1983) (41)
- Fatty acids differentially regulate hepatic cholesteryl ester formation and incorporation into lipoproteins in the liver of the mouse DOI 10.1194/jlr.M200146-JLR200 (2002) (41)
- Regulation of cholesterol metabolism. 3. (1970) (40)
- Sterol metabolism in fetal, newborn, and suckled lambs and their response to cholesterol after weaning. (1995) (39)
- Regulation of plasma levels of low-density lipoprotein cholesterol: interpretation of data on low-density lipoprotein turnover in man. (1986) (39)
- Mechanisms of LDL-cholesterol lowering action of psyllium hydrophillic mucilloid in the hamster. (1995) (38)
- Dissociation of hepatic cholesterol synthesis from hepatic low-density lipoprotein uptake and biliary cholesterol saturation in female and male hamsters of different ages. (1983) (37)
- Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal‐based diet with and without added cholesterol (1997) (37)
- The origin of cholesterol in the mesenteric lymph of the rat. (1985) (36)
- Difficulties in determining valid rate constants for transport and metabolic processes. (1970) (35)
- Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease Published, JLR Papers in Press, May 2, 2007. (2007) (35)
- Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster. (1989) (33)
- Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1. (2010) (33)
- Presence of an intact cholesterol feedback mechanism in the liver in biliary stasis. (1971) (32)
- Measurement of resistance of barriers to solute transport in vivo in rat jejunum. (1986) (31)
- Effects of Clofibrate, Cholestyramine, Zanchol, Probucol, and AOMA Feeding on Hepatic and Intestinal Cholesterol Metabolism and on Biliary Lipid Secretion in the Rat (1980) (31)
- Low density lipoprotein‐receptor activity is lost in vivo in malignantly transformed renal tissue (1986) (31)
- Rate constants for the uptake of cholesterol from various intestinal and serum lipoprotein fractions by the liver of the rat in vivo. (1977) (30)
- Intestinal kinetic parameters: effects of unstirred layers and transport preparation. (1980) (29)
- The interaction of various control mechanisms in determining the rate of hepatic cholesterogenesis in the rat. (1975) (28)
- Effect of long-chain fatty acids on low-density-lipoprotein-cholesterol metabolism. (1994) (27)
- Low and high density lipoproteins and chylomicrons as regulators of rate of cholesterol synthesis in rat liver in vivo. (1979) (27)
- DIFFUSION POTENTIALS AND POTASSIUM DISTRIBUTION ACROSS THE GALLBLADDER WALL. (1964) (26)
- Cholesterol synthesis by the gastrointestinal tract. (1971) (24)
- Kinetic characteristics and mechanisms of regulation of receptor-dependent and receptor-independent LDL transport in the liver of different animal species and humans. (1987) (23)
- Regulation of hepatic cholesterol metabolism in the rat in vivo: effect of a synthetic fat-free diet on sterol synthesis and low-density lipoprotein transport. (1995) (23)
- Enzymatic measurement of free and esterified cholesterol levels in plasma and other biological preparations using the oxygen electrode in a modified glucose analyzer. (1976) (23)
- A gas-liquid chromatographic procedure for the measurement of mevalonic acid synthesis. (1966) (22)
- Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein. (1999) (22)
- Renal cell carcinoma in the Wistar-Lewis rat: a model for studying the mechanisms of cholesterol acquisition by a tumor in vivo. (1986) (22)
- Experimental demonstration of the effect of the unstirred water layer on the kinetic constants of the membrane transport ofd-glucose in rabbit jejunum (1980) (21)
- Recent developments in solute and water transport across the gall bladder epithelium. (1966) (21)
- Mechanism of bile acid and fatty acid absorption across the unstirred water layer and brush border of the intestine. (1973) (21)
- Niemann-Pick C1 expression is not regulated by the amount of cholesterol flowing through cells in the mouse Published, JLR Papers in Press, June 1, 2005. DOI 10.1194/jlr.M500130-JLR200 (2005) (21)
- Dissociation of beta-hydroxy-beta-methylglutaryl-CoA reductase activity from the overall rate of cholesterol synthesis in the liver following the intravenous administration of lipid. (1976) (20)
- Chapter 5 Cholesterol absorption and metabolism by the intestinal epithelium (1985) (20)
- Current concepts of bile acid absorption. (1969) (19)
- Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid. (2012) (19)
- The biology of bile acids. (1972) (19)
- Modulation of the stimulatory effect of pregnenolone-16α-carbonitrile on biliary cholesterol output in the rat by manipulation of the rate of hepatic cholesterol synthesis (1984) (18)
- Regulation of Plasma Low Density Lipoprotein Levels: New Strategies for Drug Design (1987) (18)
- Normal mechanisms of fat absorption and derangements induced by various gastrointestinal diseases. (1974) (16)
- The role of the intestine in the control of cholesterol metabolism. (1969) (16)
- Approach to the malabsorption syndromes associated with disordered bile acid metabolism. (1972) (14)
- The Uptake of Lipids into the Intestinal Mucosa (1978) (12)
- Regional variation in cholesterol synthesis and low density lipoprotein transport in the brain of the fetus, newborn and adult animal (1997) (11)
- The Effect of Aging on the Processes that Regulate Plasma LDL Cholesterol Levels in Animals and Man (1987) (10)
- Active transport of 5,5-dimethyl-2,4-oxazolidinedione. (1966) (10)
- Active Transport of 5,5-Dimethyl-2,4-Oxazolidinedione (1965) (10)
- Dietary trans fatty acids and lipoprotein cholesterol. (1995) (9)
- Regulation of Low Density Lipoprotein Levels in Animals and Man with Particular Emphasis on the Role of the Liver (1986) (9)
- Regulation of biliary cholesterol output in the rat: Dissociation from the rate of cholesterol synthesis and the size of the cholesterol ester pool in the liver (1978) (8)
- Regulation of low density lipoprotein uptake and degradation in different animals species. (1984) (8)
- Diffusion studies of bile acids, fatty acids and sucrose-NaCl-water systems at 37 degrees C by a modified capillary cell apparatus and their application to membrane transport studies. (1973) (8)
- Permeability characteristics of muscle membrane. (1980) (8)
- INHIBITION OF CHOLESTEROL ABSORPTION BY SCH 58053 IN THE MOUSE IS NOT MEDIATED VIA CHANGES IN EITHER THE INTESTINAL BILE ACID POOL OR THE EXPRESSION OF mRNA FOR ABCA1, ABCG5 OR ABCG8 IN THE ENTEROCYTE (2002) (7)
- absorption of bile acids (1968) (7)
- Bile acids: their absorption from the gastrointestinal tract and role during fat absorption. (1974) (7)
- Modulation of the stimulatory effect of pregnenolone-16 alpha-carbonitrile on biliary cholesterol output in the rat by manipulation of the rate of hepatic cholesterol synthesis. (1984) (6)
- AHA Conference Report on Cholesterol. Basis for dietary treatment. (1989) (6)
- Determinants of the rate of intestinal absorption of oral cholecystographic contrast agents in the dog jejunum. (1979) (6)
- Permeability characteristics of the adipocyte cell membrane and partitioning characteristics of the adipocyte triglyceride core (1975) (6)
- Overview of cholesterol and lipoprotein metabolism in the brain, liver and extrahepatic organs (1997) (5)
- LDL cholesterol: its regulation and manipulation. (1990) (5)
- Symposium : Evolution of Ideas about the Nutritional Value of Dietary Fat Dietary Fatty Acids and the Regulation of Plasma Low Density Lipoprotein Cholesterol Concentrations 1 (1998) (4)
- Failure of adrenalcorticosteroids to influence the major mechanisms of hepatic cholesterogenesis (1974) (4)
- A rapid method to assess the hydrophobicity of the intestinal microvillus membrane in vivo. (1989) (3)
- How cholesterol metabolism and transport present novel targets for lipid treatment (2003) (2)
- Regulation of plasma LDL-cholesterol levels (1986) (2)
- Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat (1977) (2)
- 102 Treatment of the Liver Disease Associated with Niemann Pick Type C Disease with Ezetemibe and 2-Hydroxypropyl Beta Cyclodextrin Results in Near Normalization of ALT and AST (2008) (1)
- Cholesterol gallstone formation: recent advances in pathophysiology. (1973) (1)
- Disorders of the gastrointestinal tract, disorders of the liver, nutritional disorders (1976) (1)
- Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions (1988) (1)
- Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: effect on cholesterol responsiveness. (1999) (1)
- Intestinal absorption of oral cholecystographic agents (1977) (1)
- Steatorrhea associated with disordered bile acid metabolism (1969) (1)
- Mutations in NPC1 and cholesterol metabolism in the brain (2009) (1)
- Steatorrhea associated with disordered bile acid metabolism. Micellar phase defects. (1969) (0)
- Fat: absorption and malabsorption (1992) (0)
- Current status of surgery for duodenal ulcer (1967) (0)
- Theoreticalconsiderations of whatregulateslow-density lipoprotein and high-density-lipoprotein cholesterol1'2 (1997) (0)
- 565 Acute Reversal of the Lysosomal Transport Defect in the Liver of the Niemann Pick Type C Mouse (2009) (0)
- Degradation of lipoprotein cholesterol by the liver (1981) (0)
- On the establishment of a National Institute of Digestive Diseases and Nutrition. (1970) (0)
- Alzheimer's Disease and disordered cholesterol metabolism another illness to treat with statins? (2000) (0)
- Does a low plasma cholesterol concentration cause madness (1994) (0)
- Centripetal flux of cholesterol is unaltered by deletion of apo a-i: 131 (1997) (0)
- Low and high density lipoproteins and chylomicrons as regulators of rate of cholesterol synthesis in rat liver in vivo (cholesterol esters/lipoprotein clearance/lipoprotein transport) (2016) (0)
- Absorption and malabsorption (1982) (0)
- Elimination of coronary heart disease: the sequel! (1998) (0)
- Advances in the causes and treatment of colonic carcinoma (1988) (0)
- HEPATIC CHOLESTEROL ACCUMULATION AND APOPTOSIS IN THE NPC1−/− MOUSE: 94* (2005) (0)
- EFFECT OF EZETIMIBE ADMINISTERED FROM BIRTH ON HEPATIC CHOLESTEROL ACCUMULATION IN THE NIEMANN-PICK TYPE C (NPC) MOUSE: 959 (2004) (0)
- P0807 HEPATIC CHOLESTEROL ACCUMULATION IN THE NIEMANN-PICK TYPE C (NPC) MOUSE: REDUCTION WITH EZETIMIBE (2004) (0)
- Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs. (1998) (0)
- Designcriteriafor studiesexaminingindividualfatty acid effectson cardiovasculardiseaseriskfactors : humanand animalstudies 1 ' 2 (0)
- Statins and beyond the elemination of coronary artery disease (2002) (0)
- [Cholesterol and bile acid metabolism following resection of the small intestine]. (1974) (0)
- 343 Cyclodextrin Overcomes the Sterol Transport Defect in the Liver of the Niemann Pick Type C2 Mouse (2010) (0)
- Designcriteriafor studiesexaminingindividual fattyacid effectson cardiovascular diseaseriskfactors:humanand animalstudies1'2 (1997) (0)
- Medical therapy of cholesterol gallstone disease (1984) (0)
- Effect of P/S ratio (0. 5 vs 0. 9) on hepatic LDL transport at three levels of dietary cholesterol in cynomolgus macaques (1990) (0)
- Relationship between the plasma low-density lipoprotein cholesterol concentration and sterol metabolism in the central nervous system (1995) (0)
- Diseases of intestinal absorption and secretion. (1975) (0)
- M1009 2-Hydroxypropyl-β-Cyclodextrin Restores Liver Function in Niemann-Pick Type C Disease (2009) (0)
- A time for change. (1988) (0)
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