James Michael May
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James Michael Maybiology Degrees
Biology
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Neuroscience
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Biology
James Michael May's Degrees
- PhD Neuroscience Stanford University
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(Suggest an Edit or Addition)James Michael May's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2. (2009) (544)
- Reduction of Dehydroascorbate to Ascorbate by the Selenoenzyme Thioredoxin Reductase* (1997) (334)
- Protection and Recycling of α-Tocopherol in Human Erythrocytes by Intracellular Ascorbic Acid (1998) (294)
- How does ascorbic acid prevent endothelial dysfunction? (2000) (276)
- Role of vitamin C in the function of the vascular endothelium. (2013) (240)
- Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells. (1979) (220)
- Is ascorbic acid an antioxidant for the plasma membrane? (1999) (213)
- Ascorbate recycling in human erythrocytes: role of GSH in reducing dehydroascorbate. (1996) (191)
- Uptake, recycling, and antioxidant actions of α-lipoic acid in endothelial cells (2002) (184)
- Erythrocyte ascorbate recycling: antioxidant effects in blood. (1998) (183)
- Reduction of the Ascorbyl Free Radical to Ascorbate by Thioredoxin Reductase* (1998) (182)
- The insulin-like effect of hydrogen peroxide on pathways of lipid synthesis in rat adipocytes. (1979) (179)
- The mechanism of the insulin-like effects of ionic zinc. (1982) (153)
- Vitamin C transport and its role in the central nervous system. (2012) (150)
- The Concise Guide to Pharmacology 2013/14: Overview (2013) (143)
- Ascorbic acid recycling enhances the antioxidant reserve of human erythrocytes. (1995) (127)
- Inflammation in the vascular bed: importance of vitamin C. (2008) (126)
- Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity (2007) (124)
- Vitamin C promotes maturation of T-cells. (2013) (117)
- Ascorbate function and metabolism in the human erythrocyte. (1998) (116)
- Oxidative Stress Is a Mediator of Glucose Toxicity in Insulin-secreting Pancreatic Islet Cell Lines* (2004) (113)
- Mitochondrial uptake and recycling of ascorbic acid. (2001) (111)
- Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells. (2002) (95)
- Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase. (1998) (94)
- Vitamin C : Its Functions and Biochemistry in Animals and Plants (2004) (91)
- The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C (2011) (91)
- Human Erythrocyte Membranes Contain a Cytochrome b561 That May Be Involved in Extracellular Ascorbate Recycling* (2006) (89)
- Functional Organization of Mammalian Hexokinase II (1996) (88)
- Antioxidant effects of dihydrocaffeic acid in human EA.hy926 endothelial cells. (2004) (88)
- Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid (2008) (87)
- Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 transgenic and wild-type mice (2009) (83)
- Nitrite uptake and metabolism and oxidant stress in human erythrocytes. (2000) (81)
- Requirement for GSH in recycling of ascorbic acid in endothelial cells. (2001) (79)
- Interaction of ascorbate and alpha-tocopherol in resealed human erythrocyte ghosts. Transmembrane electron transfer and protection from lipid peroxidation. (1996) (79)
- Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells. (2002) (77)
- Human Erythrocyte Recycling of Ascorbic Acid (2004) (77)
- Mechanisms of ascorbic acid recycling in human erythrocytes. (2001) (75)
- Protection and recycling of alpha-tocopherol in human erythrocytes by intracellular ascorbic acid. (1998) (75)
- Ascorbic acid attenuates scopolamine-induced spatial learning deficits in the water maze (2009) (74)
- Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease (2017) (73)
- Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2. (2010) (70)
- Characterization of proinsulin-insulin intermediates in human plasma. (1978) (69)
- Mechanisms of ascorbic acid stimulation of norepinephrine synthesis in neuronal cells. (2012) (68)
- Transport and intracellular accumulation of vitamin C in endothelial cells: relevance to collagen synthesis. (2005) (68)
- Abnormal Islet and Adipocyte Function in Young B-cell-deficient Rats with Near-Normoglycemia (1984) (67)
- Reduction and uptake of methylene blue by human erythrocytes. (2004) (65)
- Ascorbate Transport and Recycling by SH-SY5Y Neuroblastoma Cells: Response to Glutamate Toxicity (2006) (62)
- Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice (2009) (61)
- Ascorbic acid efficiently enhances neuronal synthesis of norepinephrine from dopamine (2013) (60)
- Ascorbate is the major electron donor for a transmembrane oxidoreductase of human erythrocytes. (1995) (59)
- Ascorbic acid protects SH-SY5Y neuroblastoma cells from apoptosis and death induced by β-amyloid (2006) (58)
- Low ascorbic acid and increased oxidative stress in gulo(−/−) mice during development (2010) (58)
- Combined selenium and vitamin E deficiency causes fatal myopathy in guinea pigs. (2001) (58)
- Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice[S] (2014) (56)
- Extracellular reduction of the ascorbate free radical by human erythrocytes. (2000) (56)
- Combined deficiency of vitamins E and C causes paralysis and death in guinea pigs. (2003) (55)
- Plant catechols prevent lipid peroxidation in human plasma and erythrocytes (2001) (54)
- Ascorbic Acid Uptake and Regulation of Type I Collagen Synthesis in Cultured Vascular Smooth Muscle Cells (2008) (53)
- Insulin stimulation of Na+ transport and glucose metabolism in cultured kidney cells. (1982) (52)
- Vitamin C distribution and retention in the mouse brain (2010) (52)
- Uptake and antioxidant effects of ergothioneine in human erythrocytes. (1999) (51)
- Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion. (2011) (50)
- Behavioral and monoamine changes following severe vitamin C deficiency (2013) (50)
- α-Lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells (2008) (50)
- Ascorbate 6-palmitate protects human erythrocytes from oxidative damage. (1999) (49)
- Macrophage differentiation increases expression of the ascorbate transporter (SVCT2). (2009) (49)
- Recycling of vitamin C from its oxidized forms by human endothelial cells. (2003) (49)
- Glucose uptake and metabolism by cultured human skeletal muscle cells: rate-limiting steps. (2001) (45)
- Macrophage uptake and recycling of ascorbic acid: response to activation by lipopolysaccharide. (2005) (45)
- Ascorbic acid blunts oxidant stress due to menadione in endothelial cells. (2003) (44)
- Role of ascorbic acid in transferrin-independent reduction and uptake of iron by U-937 cells. (1999) (41)
- Generation of oxidant stress in cultured endothelial cells by methylene blue: protective effects of glucose and ascorbic acid. (2003) (41)
- GSH is required to recycle ascorbic acid in cultured liver cell lines. (2001) (40)
- The Effect of Endogenous Gastric Inhibitory Polypeptide on Glucose-induced Insulin Secretion in Mild Diabetes (1978) (40)
- Maturational loss of the vitamin C transporter in erythrocytes. (2007) (40)
- Glucose utilization in rat adipocytes. The interaction of transport and metabolism as affected by insulin. (1983) (40)
- Mitochondrial recycling of ascorbic acid from dehydroascorbic acid: dependence on the electron transport chain. (2002) (39)
- A combined deficiency of vitamins E and C causes severe central nervous system damage in guinea pigs. (2006) (39)
- Erythrocyte defenses against hydrogen peroxide: the role of ascorbic acid. (1998) (37)
- Ascorbate-dependent electron transfer across the human erythrocyte membrane. (1999) (37)
- Role of the C-terminal tail of the GLUT1 glucose transporter in its expression and function in Xenopus laevis oocytes. (1995) (36)
- N epsilonB29-(+)-biotinylinsulin and its complexes with avidin. Synthesis and biological activity. (1978) (36)
- Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation. (2009) (35)
- Development of ascorbate transporters in brain cortical capillary endothelial cells in culture (2008) (35)
- Ascorbic acid prevents increased endothelial permeability caused by oxidized low density lipoprotein (2010) (34)
- Redox regulation of ascorbic acid transport: Role of transporter and intracellular sulfhydryls (2004) (34)
- Vitamin C recycling and function in human monocytic U-937 cells. (1999) (34)
- Recycling of the ascorbate free radical by human erythrocyte membranes. (2001) (34)
- The simple model of adipocyte hexose transport. Kinetic features, effect of insulin, and network thermodynamic computer simulations. (1982) (33)
- Functional Interaction between the N- and C-terminal Halves of Human Hexokinase II* (1999) (33)
- Serum angiotensin converting enzyme in diabetic patients. (1993) (33)
- Coupled Glucose Transport and Metabolism in Cultured Neuronal Cells: Determination of the Rate-Limiting Step (1995) (33)
- Nitric oxide mediates tightening of the endothelial barrier by ascorbic acid. (2011) (32)
- Ascorbic acid spares α-tocopherol and decreases lipid peroxidation in neuronal cells (2003) (31)
- Ascorbic acid prevents high glucose-induced apoptosis in human brain pericytes. (2014) (31)
- Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice (2016) (31)
- Combined Vitamin C and Vitamin E Deficiency Worsens Early Atherosclerosis in Apolipoprotein E–Deficient Mice (2010) (30)
- Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin. (2018) (30)
- Regulation of embryonic neurotransmitter and tyrosine hydroxylase protein levels by ascorbic acid (2013) (30)
- Macrophage IKK&agr; Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis (2016) (29)
- Ascorbic acid spares α-tocopherol and prevents lipid peroxidation in cultured H4IIE liver cells (2003) (28)
- Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice (2010) (28)
- Glucose utilization in islets of hyperglycemic rat models with impaired glucose-induced insulin secretion. (1987) (28)
- Uptake and reduction of α-lipoic acid by human erythrocytes (2007) (27)
- Inhibition of aldose reductase in human erythrocytes by vitamin C. (1999) (27)
- Ascorbate uptake and antioxidant function in peritoneal macrophages. (2005) (26)
- Ascorbic acid prevents VEGF-induced increases in endothelial barrier permeability (2015) (26)
- Mitochondrial recycling of ascorbic acid as a mechanism for regenerating cellular ascorbate (2007) (25)
- Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain. (2016) (24)
- Triacylglycerol turnover in large and small rat adipocytes: effects of lipolytic stimulation, glucose, and insulin. (1982) (24)
- Ascorbic acid efflux and re-uptake in endothelial cells: maintenance of intracellular ascorbate (2009) (24)
- Selenium spares ascorbate and α‐tocopherol in cultured liver cell lines under oxidant stress (2001) (24)
- Selective macrophage ascorbate deficiency suppresses early atherosclerosis. (2011) (23)
- Thioredoxin Reductase Reduces Lipid Hydroperoxides and Spares α-Tocopherol (2002) (22)
- Ascorbic acid decreases oxidant stress in endothelial cells caused by the nitroxide tempol (2005) (22)
- Liposomes Containing α-Tocopherol and Ascorbate are Protected from an External Oxidant Stress (1997) (22)
- Potentiation by Glucose of Lipolytic Responsiveness of Human Adipocytes (1986) (21)
- Ascorbate-dependent protection of human erythrocytes against oxidant stress generated by extracellular diazobenzene sulfonate. (2000) (21)
- Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier. (2014) (21)
- Cobalt‐induced oxidant stress in cultured endothelial cells: Prevention by ascorbate in relation to HIF‐1α (2009) (21)
- The role of glutathione in rat adipocyte pentose phosphate cycle activity. (1981) (21)
- The inhibition of hexose transport by permeant and impermeant sulfhydryl agents in rat adipocytes. (1985) (20)
- Increased Expression of SVCT2 in a New Mouse Model Raises Ascorbic Acid in Tissues and Protects against Paraquat-Induced Oxidative Damage in Lung (2012) (20)
- Ascorbic acid prevents oxidant-induced increases in endothelial permeability. (2011) (19)
- Combined selenium and vitamin C deficiency causes cell death in guinea pig skeletal muscle. (2009) (18)
- Ascorbic acid spares alpha-tocopherol and decreases lipid peroxidation in neuronal cells. (2003) (18)
- Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice (2018) (18)
- Recycling of vitamin C by mammalian thioredoxin reductase. (2002) (18)
- Accessibility and reactivity of ascorbate 6-palmitate bound to erythrocyte membranes. (1996) (18)
- Oxidized lipoprotein induces the macrophage ascorbate transporter (SVCT2): protection by intracellular ascorbate against oxidant stress and apoptosis. (2009) (17)
- Regulation of the human ascorbate transporter SVCT2 exon 1b gene by zinc-finger transcription factors. (2011) (17)
- Intracellular Ascorbate Prevents Endothelial Barrier Permeabilization by Thrombin* (2015) (16)
- Ascorbic acid recycling by cultured beta cells: effects of increased glucose metabolism. (2004) (16)
- Monitoring conformational change in the human erythrocyte glucose carrier: use of a fluorescent probe attached to an exofacial carrier sulfhydryl. (1993) (16)
- Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. (1994) (16)
- Ascorbic acid transport in brain microvascular pericytes. (2015) (15)
- Localization of a reactive exofacial sulfhydryl on the glucose carrier of human erythrocytes. (1990) (15)
- Intracellular ascorbate tightens the endothelial permeability barrier through Epac1 and the tubulin cytoskeleton. (2016) (15)
- Reaction of an exofacial sulfhydryl group on the erythrocyte hexose carrier with an impermeant maleimide. Relevance to the mechanism of hexose transport. (1988) (15)
- Control of glucose phosphorylation in L6 myotubes by compartmentalization, hexokinase, and glucose transport. (2003) (14)
- Ascorbic acid spares alpha-tocopherol and prevents lipid peroxidation in cultured H4IIE liver cells. (2003) (13)
- Nitric oxide-induced oxidant stress in endothelial cells: amelioration by ascorbic acid. (2004) (13)
- CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a. (2011) (13)
- Ascorbic acid repletion: A possible therapy for diabetic macular edema? (2016) (13)
- Thiol‐fatty acylation of the glucose transport protein of human erythrocytes (1990) (13)
- Nitrite Generates an Oxidant Stress and Increases Nitric Oxide in EA.hy926 Endothelial Cells (2004) (12)
- Location and recycling of mitochondrial α-tocopherol (2003) (12)
- Inhibition of hexose transport and labelling of the hexose carrier in human erythrocytes by an impermeant maleimide derivative of maltose. (1988) (12)
- Determinants of gastric inhibitory polypeptide and insulin secretion. (1981) (12)
- Coupling of glucose transport and phosphorylation in Xenopus oocytes and cultured cells: Determination of the rate‐limiting step (1993) (11)
- Oxidized LDL up-regulates the ascorbic acid transporter SVCT2 in endothelial cells (2010) (11)
- Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity. (2006) (11)
- Uptake and reduction of alpha-lipoic acid by human erythrocytes. (2007) (11)
- Catalase-dependent measurement of H2O2 in intact mitochondria. (2002) (11)
- Interaction of a permeant maleimide derivative of cysteine with the erythrocyte glucose carrier. Differential labelling of an exofacial carrier thiol group and its role in the transport mechanism. (1989) (11)
- Labeling of human erythrocyte band 3 with maltosylisothiocyanate. Interaction with the anion transporter. (1987) (11)
- Inhibition of hexose transport by adenosine derivatives in human erythrocytes (1988) (11)
- A "cysteineless" GLUT1 glucose transporter has normal function when expressed in Xenopus oocytes. (1995) (10)
- Selective labeling of the erythrocyte hexose carrier with a maleimide derivative of glucosamine: relationship of an exofacial sulfhydryl to carrier conformation and structure. (1989) (10)
- Ascorbic acid catabolism: breakdown pathways in animals and plants (2004) (10)
- Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice (2019) (10)
- Interaction of the Transcription Start Site Core Region and Transcription Factor YY1 Determine Ascorbate Transporter SVCT2 Exon 1a Promoter Activity (2012) (9)
- Differential labeling of the erythrocyte hexose carrier by N-ethylmaleimide: correlation of transport inhibition with reactive carrier sulfhydryl groups. (1989) (9)
- Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C? (2010) (9)
- Similarities in the metabolism of alloxan and dehydroascorbate in human erythrocytes. (1998) (8)
- Ascorbic acid efflux from human brain microvascular pericytes: role of re-uptake. (2015) (8)
- Thioredoxin reductase reduces lipid hydroperoxides and spares alpha-tocopherol. (2002) (8)
- Ligand-induced conformational changes modify proteolytic cleavage of the adipocyte insulin-sensitive glucose transporter. (1993) (7)
- Photolabeling of the human erythrocyte glucose carrier with androgenic steroids. (1988) (7)
- Photoaffinity labeling of glyceraldehyde-3-phosphate dehydrogenase by an aryl azide derivative of glucosamine in human erythrocytes. (1986) (7)
- Combined vitamin C and E deficiency induces motor defects in gulo−/−/SVCT2+/− mice (2013) (7)
- Troglitazone protects human erythrocytes from oxidant damage. (2000) (7)
- Abstract 15960: Macrophage IKKalpha Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival and Decreases Early Atherosclerosis (2013) (6)
- Human Erythrocyte Recycling of Ascorbic Acid: Relative Contributions from the Ascorbate Free Radical and Dehydroascorbic Acid (2004) (5)
- Testing models of insulin binding in rat adipocytes using network thermodynamic computer simulations. (1986) (5)
- Rat adipocyte utilization of different substrates: Effects of cell size and the control of lipogenesis (1982) (5)
- Liposomes containing alpha-tocopherol and ascorbate are protected from an external oxidant stress. (1997) (5)
- Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids. (2012) (5)
- Tryptic digestion of the human erythrocyte glucose transporter: effects on ligand binding and tryptophan fluorescence. (1993) (5)
- Location and recycling of mitochondrial alpha-tocopherol. (2003) (5)
- In vitro phosphorylation of a synthetic collagen peptide by cyclic AMP-dependent protein kinase. (1984) (4)
- The inhibition of hexose transport and metabolism by small amounts of adenosine 5'-triphosphate in isolated rat adipocytes. (1982) (4)
- Selenium spares ascorbate and alpha-tocopherol in cultured liver cell lines under oxidant stress. (2001) (4)
- Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice (2021) (3)
- Interaction of Ascorbate and -Tocopherol in Resealed Human Erythrocyte Ghosts (1996) (3)
- Effects of ATP depletion on the mechanism of hexose transport in intact human erythrocytes (1988) (3)
- Assessing the reductive capacity of cells by measuring the recycling of ascorbic and lipoic acids. (2010) (3)
- The effect of insulin-stimulated pentose phosphate cycle activity on cellular glutathione content in rat adipocytes. (1982) (3)
- Sodium‐dependent vitamin C transporter‐2 mediates vitamin C transport at the cortical nerve terminal (2015) (3)
- The one-site model of human erythrocyte glucose transport: testing its predictions using network thermodynamic computer simulations. (1991) (2)
- Ascorbic acid in the central nervous system: uptake, distribution and functions (2004) (2)
- Dietary allowances for vitamin C: Recommended Dietary Allowances and optimal nutrient ingestion (2004) (2)
- Photolabeling of the adipocyte hexose carrier with an aryl azide derivative of maltose (1987) (2)
- Famine From Feast: Low Red Cell Vitamin C Levels in Diabetes☆ (2015) (2)
- Medical aspects of the development of scurvy: past and present (2013) (2)
- Correction: Increased Expression of SVCT2 in a New Mouse Model Raises Ascorbic Acid in Tissues and Protects against Paraquat-Induced Oxidative Damage in Lung (2012) (1)
- Inhibition of hexose transport in the human erythrocyte by 5, 5′-dithiobis(2-nitrobenzoic acid): Role of an exofacial carrier sulfhydryl group (1989) (1)
- Interactions of selenium, vitamin E, and vitamin C in atherosclerosis (2002) (1)
- The insulin-like effects of low molecular weight thiols: role of trace metal contamination of commercial thiols. (1980) (1)
- Abnormal total NADP+ and glutathione and impaired glucose metabolism of large rat adipocytes (1980) (1)
- The expression of biologically active recombinant ricin A chain "in vitro" (1988) (0)
- Abstract 549: Loss of Macrophage Akt2/Akt3 or Akt1/Akt2 Decreases Cell Survival and Suppresses Early Atherosclerosis in Ldlr Null Mice (2015) (0)
- SLC23 family of ascorbic acid transporters in GtoPdb v.2021.3 (2021) (0)
- skeletal muscle cells: rate-limiting steps Glucose uptake and metabolism by cultured human (2016) (0)
- Is ascorbic acid an antioxidant for the plasma membrane? (2020) (0)
- Microsoft Word-Manuscript_Track Changes.docx (2015) (0)
- Erratum (2013) (0)
- Abstract 15417: Macrophage Deficiency of Akt2 or Both Akt1 and Akt2 Reduces Atherosclerosis: Akt is Critical for Macrophage Polarization and Survival (2013) (0)
- SLC23 family of ascorbic acid transporters (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- N EB2g-( +)-Biotinylinsulin and Its Complexes with Avidin (2011) (0)
- Role of short-term α-lipoic acid therapy in patients with hypercholesterolemia to reverse oxidative stress and endothelial dysfunction (2015) (0)
- Ingestive Behavior and Neurosciences A Combined Deficiency of Vitamins E and C Causes Severe Central Nervous System Damage in Guinea Pigs 1 , 2 (2006) (0)
- Abstract 2: Loss of Rictor in Macrophages Suppresses Their Viability and Reduces Atherosclerosis in LDLR Null Mice (2016) (0)
- Abstract 129: Overexpression of P110alpha Induces Vascular Malformation in Mouse Tail, Feet and Ears (2016) (0)
- Ascorbic acid prevents VEGF-induced increases in endothelial barrier permeability (2015) (0)
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James Michael May is affiliated with the following schools: