J. Michael Mccune
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Philosophy Biology
J. Michael Mccune's Degrees
- Doctorate Medicine University of Colorado
- PhD Immunology University of Colorado
Why Is J. Michael Mccune Influential?
(Suggest an Edit or Addition)J. Michael Mccune's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. (1988) (1410)
- Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero (2008) (762)
- Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. (2001) (700)
- Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection (2008) (693)
- Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. (2008) (653)
- Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans (1999) (634)
- The dynamics of CD4+ T-cell depletion in HIV disease (2001) (619)
- Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: implications for T-cell homeostasis (2001) (567)
- Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism (2013) (550)
- Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus (1988) (536)
- Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease (2010) (503)
- HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality (2014) (484)
- Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1 (1998) (425)
- HIV induces thymus depletion in vivo (1993) (412)
- Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection (2009) (406)
- Immune mechanisms at the maternal-fetal interface: perspectives and challenges (2015) (398)
- Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. (2001) (389)
- Infection of the SCID-hu mouse by HIV-1. (1988) (373)
- International AIDS Society global scientific strategy: towards an HIV cure 2016 (2016) (372)
- Fetal and Adult Hematopoietic Stem Cells Give Rise to Distinct T Cell Lineages in Humans (2010) (371)
- Long-term human hematopoiesis in the SCID-hu mouse (1990) (354)
- Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. (2007) (315)
- Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. (2013) (298)
- Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells* (2009) (284)
- Defining total-body AIDS-virus burden with implications for curative strategies (2017) (279)
- Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse (1993) (279)
- Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA (2002) (272)
- Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses (2006) (261)
- Factors influencing T-cell turnover in HIV-1-seropositive patients. (2000) (258)
- Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function (2001) (256)
- High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection. (1998) (256)
- HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo. (1995) (244)
- Direct Evidence for Thymic Function in Adult Humans (1999) (242)
- HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control (2008) (232)
- Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection. (2003) (227)
- Phenotypic, Functional, and Kinetic Parameters Associated with Apparent T-Cell Control of Human Immunodeficiency Virus Replication in Individuals with and without Antiretroviral Treatment (2005) (225)
- Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells. (2003) (212)
- Isolation and immunologic characterization of a human. B-lymphocyte- specific, cell surface antigen (1976) (211)
- Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. (2013) (211)
- Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy (2008) (209)
- Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon (2012) (205)
- Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus (2012) (203)
- IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient (2010) (197)
- A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. (2011) (197)
- Suppression of HIV infection in AZT-treated SCID-hu mice. (1990) (195)
- Defining HIV and SIV Reservoirs in Lymphoid Tissues (2016) (195)
- Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease (2010) (191)
- Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. (2013) (177)
- Growth hormone enhances thymic function in HIV-1-infected adults. (2008) (172)
- HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study (2017) (171)
- Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. (2000) (169)
- Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells (1991) (167)
- Neutralizing Antibody Responses against Autologous and Heterologous Viruses in Acute versus Chronic Human Immunodeficiency Virus (HIV) Infection: Evidence for a Constraint on the Ability of HIV To Completely Evade Neutralizing Antibody Responses (2006) (166)
- Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia. (2006) (159)
- Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE ε4/ε4 genotype accelerates HIV disease progression (2008) (158)
- Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone (2002) (155)
- The SCID-hu mouse: a small animal model for HIV infection and pathogenesis. (1991) (153)
- Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection (2003) (153)
- Impaired replication of protease inhibitor-resistant HIV-1 in human thymus (2001) (153)
- Th17 and regulatory T cells: implications for AIDS pathogenesis (2010) (150)
- Gut epithelial barrier and systemic inflammation during chronic HIV infection (2015) (147)
- Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization (2009) (144)
- A Low T Regulatory Cell Response May Contribute to Both Viral Control and Generalized Immune Activation in HIV Controllers (2011) (140)
- Breaking Free of Sample Size Dogma to Perform Innovative Translational Research (2011) (140)
- Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. (2006) (136)
- A Sound Rationale Needed for Phase III HIV-1 Vaccine Trials (2004) (133)
- Hematopoietic-stem-cell-based gene therapy for HIV disease. (2012) (132)
- Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent. (1991) (130)
- CCR5- and CXCR4-Utilizing Strains of Human Immunodeficiency Virus Type 1 Exhibit Differential Tropism and Pathogenesis In Vivo (1998) (130)
- Immunosenescence and HIV. (2012) (130)
- Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection (2014) (128)
- Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication. (1993) (127)
- Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner. (1991) (124)
- T cell turnover in HIV-1 disease. (1997) (122)
- CXCR4 and CCR5 expression delineates targets for HIV-1 disruption of T cell differentiation. (1998) (121)
- Implantation and maintenance of functional human bone marrow in SCID-hu mice. (1992) (119)
- Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis (1996) (119)
- Loss of cytomegalovirus-specific CD4+ T cell responses in human immunodeficiency virus type 1-infected patients with high CD4+ T cell counts and recurrent retinitis. (2001) (119)
- Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice (1999) (119)
- Immunological tolerance during fetal development: from mouse to man. (2012) (117)
- HIV-1: The infective process in vivo (1991) (117)
- CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy. (2002) (116)
- Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse (1994) (113)
- Regulation of T Cell Responses in the Developing Human Fetus1 (2006) (112)
- Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects. (2001) (108)
- Human Immunodeficiency Virus Type 1 Nef-Mediated Downregulation of CD4 Correlates with Nef Enhancement of Viral Pathogenesis (2003) (107)
- HIV‐Infected Liver and Kidney Transplant Recipients: 1‐ and 3‐Year Outcomes (2008) (106)
- Implantation and maintenance of functional human bone marrow in SCID-hu mice (1992) (105)
- Prospective Antiretroviral Treatment of Asymptomatic, HIV-1 Infected Controllers (2013) (105)
- Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo. (1998) (101)
- The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy. (2014) (99)
- Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry (1996) (98)
- Identification of Cinnabarinic Acid as a Novel Endogenous Aryl Hydrocarbon Receptor Ligand That Drives IL-22 Production (2014) (97)
- IFN-α Secretion by Type 2 Predendritic Cells Up-Regulates MHC Class I in the HIV-1-Infected Thymus1 (2002) (94)
- Loss of T cell responses following long-term cryopreservation. (2007) (94)
- Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication (2007) (93)
- Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1. (2004) (92)
- Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease (2014) (89)
- Gene expression profiles during human CD4+ T cell differentiation. (2004) (89)
- Th17 cells and regulatory T cells in elite control over HIV and SIV (2011) (88)
- Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging (2014) (87)
- Multiparameter evaluation of human thymic function: interpretations and caveats. (2005) (79)
- Central Memory CD8+ T Cells Appear to Have a Shorter Lifespan and Reduced Abundance as a Function of HIV Disease Progression1 (2008) (79)
- IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. (2016) (78)
- Glucose Transporter 1–Expressing Proinflammatory Monocytes Are Elevated in Combination Antiretroviral Therapy–Treated and Untreated HIV+ Subjects (2014) (78)
- Thymic function in HIV-1 disease. (1997) (76)
- Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouse. (1991) (75)
- A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis (2012) (75)
- IL-21 and Probiotic Therapy Improve TH17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques (2015) (75)
- Expression of the Autoimmune Susceptibility Gene FcRL3 on Human Regulatory T Cells Is Associated with Dysfunction and High Levels of Programmed Cell Death-1 (2010) (73)
- Two types of Ia-positive T cells. Synthesis and exchange of Ia antigens. (1980) (73)
- Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. (2015) (72)
- Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds (1996) (72)
- Development and applications of the SCID-hu mouse model. (1996) (72)
- Viral latency in HIV disease (1995) (71)
- Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. (2009) (71)
- Why and where an HIV cure is needed and how it might be achieved (2019) (67)
- Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia (1980) (67)
- Upregulation of Retinal Dehydrogenase 2 in Alternatively Activated Macrophages during Retinoid-dependent Type-2 Immunity to Helminth Infection in Mice (2012) (66)
- Reversal of human immunodeficiency virus type 1-associated hematosuppression by effective antiretroviral therapy. (2000) (66)
- IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. (2013) (64)
- Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase (2011) (64)
- Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. (2017) (62)
- Short‐Term Effects of Cannabinoids on Immune Phenotype and Function in HIV‐1‐Infected Patients (2002) (59)
- Cytomegalovirus (CMV)-specific CD4+ T lymphocyte immune function in long-term survivors of AIDS-related CMV end-organ disease who are receiving potent antiretroviral therapy. (2001) (57)
- Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. (2014) (56)
- Growth Hormone–Induced Stimulation of Multilineage Human Hematopoiesis (2005) (56)
- The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial (2014) (56)
- Human Herpesvirus 6 (HHV-6) Causes Severe Thymocyte Depletion in SCID-hu Thy/Liv Mice (1999) (55)
- J chain biosynthesis in pre-B cells and other possible precursor B cells (1981) (55)
- Impact of early cART in the gut during acute HIV infection. (2016) (54)
- A Membrane-bound Fas Decoy Receptor Expressed by Human Thymocytes* (2000) (54)
- Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection (2017) (54)
- Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression (2007) (54)
- Development of a human thymic organ culture model for the study of HIV pathogenesis. (1995) (53)
- Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse. (1991) (53)
- Effect of SIVmac infection on plasmacytoid and CD1c+ myeloid dendritic cells in cynomolgus macaques (2008) (52)
- Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals (2017) (51)
- Enhanced representation of HL-A antigens on human lymphocytes after mitogenesis induced by phytohemagglutinin or Epstein-Barr virus. (1975) (51)
- Effects of IL-7 on Early Human Thymocyte Progenitor Cells In Vitro and in SCID-hu Thy/Liv Mice1 (2003) (50)
- IFN-α-Induced Upregulation of CCR5 Leads to Expanded HIV Tropism In Vivo (2010) (48)
- Distinct functional programming of human fetal and adult monocytes. (2014) (48)
- Morphine Produces Immunosuppressive Effects in Nonhuman Primates at the Proteomic and Cellular Levels* (2012) (48)
- HIV-Induced Changes in T Cell Signaling Pathways1 (2008) (46)
- Blood T-cell receptor diversity decreases during the course of HIV infection, but the potential for a diverse repertoire persists. (2012) (45)
- The human fetal immune response to hepatitis C virus exposure in utero. (2011) (45)
- Animal Models of HIV-1 Disease (1997) (43)
- Generation of CD3+CD8low Thymocytes in the HIV Type 1-Infected Thymus1 (2002) (42)
- Composition and Function of T Cell Subpopulations Are Slow to Change Despite Effective Antiretroviral Treatment of HIV Disease (2014) (42)
- In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis. (2008) (40)
- Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N- termini and different C-termini (1980) (40)
- SIV Replication in the Infected Rhesus Macaque Is Limited by the Size of the Preexisting TH17 Cell Compartment (2012) (40)
- Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers. (2010) (39)
- HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers. (2011) (38)
- Long-term changes in circulating CD4 T lymphocytes in virologically suppressed patients after 6 years of highly active antiretroviral therapy (2004) (37)
- Isolation of peripheral blood CD4(+) T cells using RosetteSep and MACS for studies of DNA turnover by deuterium labeling. (2004) (37)
- Identification of HIV-1 determinants for replication in vivo. (1997) (37)
- Antiviral Activity of 2′-Deoxy-3′-Oxa-4′-Thiocytidine (BCH-10652) against Lamivudine-Resistant Human Immunodeficiency Virus Type 1 in SCID-hu Thy/Liv Mice (2000) (35)
- Lin28b Regulates Fetal Regulatory T Cell Differentiation through Modulation of TGF-β Signaling (2016) (35)
- Naive Human T Cells Are Activated and Proliferate in Response to the Heme Oxygenase-1 Inhibitor Tin Mesoporphyrin (2010) (34)
- Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: evidence of indirect mechanisms. (1999) (34)
- The Immunoglobulin‐Like Structure of Human Histocompatibility Antigens (1974) (34)
- Preclinical Evaluation of Human Hematolymphoid Function in the SCID‐hu Mouse (1991) (33)
- Can HIV be cured with stem cell therapy? (2010) (31)
- Human hematolymphoid cells in SCID mice. (1994) (30)
- At the crossroads between tolerance and aggression (2011) (30)
- A Cure for HIV Infection: “Not in My Lifetime” or “Just Around the Corner”? (2016) (29)
- Direct measurement of T-cell receptor repertoire diversity with AmpliCot (2006) (29)
- The case for an HIV cure and how to get there (2020) (29)
- SCID mice as immune system models. (1991) (29)
- TCF-1 regulates HIV-specific CD8+ T cell expansion capacity (2020) (28)
- HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells. (2011) (28)
- Discordance Between Peripheral and Colonic Markers of Inflammation During Suppressive ART (2014) (27)
- Inhibition of Human Immunodeficiency Virus Type 1 Infection in SCID-hu Thy/Liv Mice by the G-Quartet-Forming Oligonucleotide, ISIS 5320 (1998) (27)
- Direct evaluation of radiation damage in human hematopoietic progenitor cells in vivo. (1994) (26)
- Gag p27-Specific B- and T-Cell Responses in Simian Immunodeficiency Virus SIVagm-Infected African Green Monkeys (2008) (25)
- Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro. (1981) (25)
- A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity. (2012) (25)
- Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal. (1999) (25)
- IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells (2006) (25)
- R5 Strains of Human Immunodeficiency Virus Type 1 from Rapid Progressors Lacking X4 Strains Do Not Possess X4-Type Pathogenicity in Human Thymus (1999) (24)
- Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African Americans (2011) (23)
- Multi-stakeholder consensus on a target product profile for an HIV cure (2020) (23)
- Successful allogeneic bone marrow transplant in an HIV-1-positive man with chronic myelogenous leukemia. (2000) (23)
- Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: a randomized placebo-controlled study. (2007) (21)
- Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen (1987) (21)
- The scid-hu mouse: current status and potential applications. (1989) (21)
- HIV-1-Specific CD4+ T Cell Responses in Chronically HIV-1 Infected Blippers on Antiretroviral Therapy in Relation to Viral Replication Following Treatment Interruption (2006) (20)
- Causal relationships between HIV-1 coreceptor utilization, tropism, and pathogenesis in human thymus. (2000) (20)
- Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase. (2012) (20)
- Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection (2020) (20)
- Elucidating the Burden of HIV in Tissues Using Multiplexed Immunofluorescence and In Situ Hybridization: Methods for the Single-Cell Phenotypic Characterization of Cells Harboring HIV In Situ (2018) (19)
- Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART (2021) (19)
- Myeloid‐Lymphoid Ontogeny in the Rhesus Monkey (Macaca mulatta) (2014) (19)
- Superantigen-mediated deletion of specific T cell receptor V beta subsets in the SCID-hu Thy/Liv mouse is induced by staphylococcal enterotoxin B, but not HIV-1. (1997) (19)
- The Ban on US Government Funding Research Using Human Fetal Tissues: How Does This Fit with the NIH Mission to Advance Medical Science for the Benefit of the Citizenry? (2019) (19)
- Coinfection of SCID-hu Thy/Liv Mice with Human Herpesvirus 6 and Human Immunodeficiency Virus Type 1 (2000) (19)
- Today's SCID-hu mouse (1990) (18)
- Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. (2017) (18)
- Immunologic profiles distinguish aviremic HIV-infected adults (2016) (18)
- Increased Circulating Interleukin-7 Levels in HIV-1-Infected Women (2005) (17)
- IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8+ T Cell Responses in Acute Simian Immunodeficiency Virus Infection. (2017) (16)
- Pseudotypes in HIV-infected mice. (1990) (16)
- Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir. (2015) (16)
- Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains (1981) (16)
- HIV tropism and CD4+ T-cell depletion (2002) (15)
- The Role of Transplacental Microtransfusions of Maternal Lymphocytes in In Utero HIV Transmission (2010) (13)
- Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. (2021) (13)
- Colony-Stimulating Factor 1 Receptor Antagonists Sensitize Human Immunodeficiency Virus Type 1-Infected Macrophages to TRAIL-Mediated Killing (2016) (13)
- Immune Activation, Cd4+ T Cell Counts, and Viremia Exhibit Oscillatory Patterns over Time in Patients with Highly Resistant HIV Infection (2011) (13)
- Enhanced Replication of R5 HIV-1 Over X4 HIV-1 in CD4+CCR5+CXCR4+ T Cells (2005) (13)
- Analysis of maternal microchimerism in rhesus monkeys (Macaca mulatta) using real-time quantitative PCR amplification of MHC polymorphisms (2014) (13)
- Human neural xenografts: progress in developing an in-vivo model to study human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV) infection. (1994) (12)
- The SCID-hu mouse: a small animal model for the analysis of human hematolymphoid differentiation and function. (1992) (12)
- Distinct Functional Programs in Fetal T and Myeloid Lineages (2014) (12)
- The Hematopathology of HIV-1 Disease: Experimental Analysis in Vivo (1995) (12)
- Ig biosynthesis in a human pre-B cell line. (1981) (12)
- A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function (2018) (11)
- CD57+ Memory T Cells Proliferate In Vivo (2020) (10)
- Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post–Combination Antiretroviral Therapy CD4+ T Cell Counts and Body Weight (2019) (10)
- Generation of CD3 CD8 Thymocytes in the HIV Type 1-Infected Thymus (2002) (10)
- CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals (2019) (9)
- Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. (2019) (9)
- HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives (2021) (8)
- Higher CD27+CD8+ T Cells Percentages during Suppressive Antiretroviral Therapy Predict Greater Subsequent CD4+ T Cell Recovery in Treated HIV Infection (2013) (8)
- Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge (2015) (8)
- HIV “cure”: A shot in the arm? (2019) (8)
- Design, construction, and validation of a modular library of sequence diversity standards for polymerase chain reaction. (2011) (8)
- Generation of CD 3 CD 8 low Thymocytes in the HIV Type 1-Infected Thymus 1 (2002) (7)
- Measurement of absolute T cell receptor rearrangement diversity. (2011) (7)
- Glut1 Expression Level on Inflammatory Monocytes is Associated With Markers of Cardiovascular Disease Risk in HIV-Infected Individuals (2017) (7)
- Preclinical Evaluation of Antiviral Compounds in the SCID‐hu Mouse (1990) (7)
- TCF-1 regulates the stem-like memory potential of HIV-specific CD8+ T cells in elite controllers (2020) (5)
- A Plea for Justice for Jailed Medical Workers (2006) (5)
- The diversity of T cells. (2001) (4)
- Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection. (2014) (4)
- A Simple Flow Cytometric Method to Measure Glucose Uptake and Glucose Transporter Expression for Monocyte Subpopulations in Whole Blood. (2016) (4)
- Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success (2018) (3)
- The immunoglobulin-like structure of human histocompatibility antigens. (1976) (3)
- Epstein-Barr virus associated lymphoproliferative disease in mice and men. (1991) (3)
- Humanized Mice as Models for Human Disease (2014) (3)
- Viral Latency in HIV Disease Review (1995) (3)
- Relative mRNA Expression Levels of Restriction Factors and Antiviral Genes in Fetal and Adult Human Monocytes and Monocyte-Derived Macrophages. (2017) (3)
- Reply to Pomara et al. and Valcour et al.: Age and the APOE ε4/ε4 genotype in HIV-1-associated dementia (2008) (2)
- Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease (2015) (2)
- IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health (2022) (2)
- Collaborative science to advance gene therapies in resource-limited parts of the world. (2021) (2)
- The SCID-hu Mouse: A Small Animal Model for HIV Infection and Antiviral Testing (1989) (2)
- Some Aspects of CD8+ T Cell Exhaustion are Associated with Altered T Cell Mitochondrial Features and ROS content in HIV Infection. (2019) (2)
- Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World (2020) (2)
- A functional variant in FCRL3 is associated with higher FcRL3 expression on T cell subsets and rheumatoid arthritis disease activity (2012) (2)
- Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4+ T cell recovery after the initiation of antiretroviral therapy for HIV disease (2014) (2)
- Direct Measurement of CD41 and CD81 T-Cell Responses to CMV in HIV-1-Infected Subjects (2001) (2)
- Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. (2006) (2)
- Mechanisms of T-Cell Depletion and Regeneration in HIV Disease (2002) (2)
- Gene expression profiles during human CD 4 1 T cell differentiation (2004) (2)
- Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Hematopoiesis (2020) (1)
- HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes (American Journal of Transplantation (2008) 8: 2 (355-365) DOI: 10.1111/j.1600-6143.2007.02061.x) (2008) (1)
- Development and Reconstitution of T-Lymphoid Immunity (2001) (1)
- Potential inflammatory consequences in HIV controllers (2010) (1)
- Gag p 27-Specific Band T-Cell Responses in Simian Immunodeficiency Virus SIVagm-Infected African Green Monkeys (2009) (1)
- Human fetal T cells: Insights into developmental specialization and mechanisms of lineage transition. (2023) (1)
- Track A Basic Science (2012) (1)
- Faculty Opinions recommendation of mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function. (2013) (1)
- Faculty Opinions recommendation of Environmental biodiversity, human microbiota, and allergy are interrelated. (2012) (0)
- How the immune system ‘Grows up’: evidence supporting the existence of a layered immune system (2010) (0)
- Subjects + Treated and Untreated HIV - Combination Antiretroviral Therapy Proinflammatory Monocytes Are Elevated in Expressing - Glucose Transporter 1 (2014) (0)
- Faculty Opinions recommendation of Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties. (2010) (0)
- HIV and the cells it infects: sorting the latent from the labile. An interview with Mike McCune, MD, PhD. Interview by Mark Mascolini. (1996) (0)
- of Programmed Cell Death-1 Associated with Dysfunction and High Levels Is Gene FcRL3 on Human Regulatory T Cells Expression of the Autoimmune Susceptibility (2010) (0)
- From academia to biotechnology – and back (2012) (0)
- Oxygenase-1 Inhibitor Tin Mesoporphyrin Proliferate in Response to the Heme Naive Human T Cells Are Activated and (2010) (0)
- Apoptotic Signal Development But Does Not Transmit an Fas Is Expressed Early in Human Thymocyte (1999) (0)
- How we achieve tolerance for our mothers: evidence for a layered immune system in humans (64.1) (2011) (0)
- Human lymph-tissue in a host immunocompromised (1991) (0)
- Faculty Opinions recommendation of Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. (2010) (0)
- Tu1745 Intestinal Epithelial Apoptosis and Immune Activation During HIV Infection (2013) (0)
- Thy/Liv Progenitor Cells In Vitro and in SCID-hu Effects of IL-7 on Early Human Thymocyte (2003) (0)
- ProgressionAbundance as a Function of HIV Disease Have a Shorter Lifespan and Reduced T Cells Appear to + Central Memory CD8 (2008) (0)
- Henry Kunkel and the teaching of patient-oriented research. (2016) (0)
- Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication (cid:1) (2007) (0)
- Supplemental Information Mass Cytometric Analysis of HIV Entry , Replication , and Remodeling in Tissue CD 4 + T Cells (0)
- Chapter 2 Humanized Mice as Models for Human Disease (2018) (0)
- Faculty Opinions recommendation of Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. (2014) (0)
- Differentiation Targets for HIV-1 Disruption of T Cell CXCR4 and CCR5 Expression Delineates (1998) (0)
- MAMMAL COMPROSING WASCULARIZED FETAL, ORGAN TISSUE (2017) (0)
- Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naïve T Cells (2020) (0)
- HIV-1-Infected Thymus UpRegulates MHC Class I in the Secretion by Type 2 Predendritic Cells α IFN - (2001) (0)
- IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection (VIR6P.1162) (2015) (0)
- Times , They are a-Changing The outcome of the US elections in the fall of 2002 (0)
- Clonal integration site expansion of infected cells is a main contributor of HIV persistence in more differentiated T cell subsets during suppressive ART (2019) (0)
- Intact HIV genomes are enriched in memory T cells with short half-lives (2019) (0)
- Denatured zenogeneic transplanted organ system at immunized host (1991) (0)
- Pathogenesis of HIV Infection (2005) (0)
- Opportunistic pricing: a new scourge, a new call for action. (1998) (0)
- Faculty Opinions recommendation of HIV-1 persistence in CD4+ T cells with stem cell-like properties. (2014) (0)
- Mechanisms of CD4+ T-cell depletion in HIV disease (2003) (0)
- HIV disease progression and dysfunctional naive CD8low T cells: implications in pregnancy? (2012) (0)
- SCID-hu Thy / Liv Mice : Evidence of Indirect Immature Thymocytes in HIV-1-Infected Induction of MHC Class I Expression on Kaneshima and Lishan (1999) (0)
- CD4+CD25high Regulatory T Cells in the Developing Human Immune System: Implications for Pediatric HIV Infection (2005) (0)
- Diversity of the Immune system (2018) (0)
- Brief Definitive Report Biogenesis of Membrane-bound and Secreted Immunoglobulins I. Two Distinct Translation Products of Human/x-chain, with Identical N-termini and Different C-termini* (2003) (0)
- Furry flasks? (1998) (0)
- Update on IL-2 : Where It ’ s Been and Where It ’ s Going (0)
- Amino acid use due to activation of murine lymphocyte subsets (2010) (0)
- Correction: Central Memory CD8+ T Cells Appear to Have a Shorter Lifespan and Reduced Abundance as a Function of HIV Disease Progression (2012) (0)
- Information , Inspiration and Advocacy for People Living with HIV / AIDS (2004) (0)
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