John Michael Mcintosh
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Biology
John Michael Mcintosh's Degrees
- Bachelors Biology University of California, Santa Cruz
- PhD Neuroscience Stanford University
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(Suggest an Edit or Addition)John Michael Mcintosh's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Peptide neurotoxins from fish-hunting cone snails. (1985) (702)
- The odyssey of marine pharmaceuticals: a current pipeline perspective. (2010) (585)
- Subunit Composition of Functional Nicotinic Receptors in Dopaminergic Neurons Investigated with Knock-Out Mice (2003) (522)
- A new conus peptide ligand for mammalian presynaptic Ca2+ channels (1992) (490)
- Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. (2004) (435)
- Identification of the Nicotinic Receptor Subtypes Expressed on Dopaminergic Terminals in the Rat Striatum (2002) (411)
- A New -Conotoxin Which Targets 32 Nicotinic Acetylcholine Receptors (*) (1996) (407)
- Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. (1984) (398)
- Distribution and Pharmacology of α6-Containing Nicotinic Acetylcholine Receptors Analyzed with Mutant Mice (2002) (363)
- Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venom. (1987) (320)
- Crucial Role of α4 and α6 Nicotinic Acetylcholine Receptor Subunits from Ventral Tegmental Area in Systemic Nicotine Self-Administration (2008) (317)
- α-Conotoxin AuIB Selectively Blocks α3β4 Nicotinic Acetylcholine Receptors and Nicotine-Evoked Norepinephrine Release (1998) (287)
- Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes. (1999) (281)
- Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors (2003) (261)
- The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum. (2007) (260)
- α6-Containing Nicotinic Acetylcholine Receptors Dominate the Nicotine Control of Dopamine Neurotransmission in Nucleus Accumbens (2008) (246)
- α-Conotoxin MII Blocks Nicotine-Stimulated Dopamine Release in Rat Striatal Synaptosomes (1997) (227)
- Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors (2006) (211)
- In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity α6∗ Nicotinic Acetylcholine Receptors (2008) (200)
- The β3 Nicotinic Receptor Subunit: A Component of α-Conotoxin MII-Binding Nicotinic Acetylcholine Receptors that Modulate Dopamine Release and Related Behaviors (2003) (190)
- Analogs of α-conotoxin MII are selective for α6-containing nicotinic acetylcholine receptors (2004) (181)
- 125I-alpha-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain. (2000) (175)
- Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum (2001) (170)
- A nicotinic acetylcholine receptor ligand of unique specificity, alpha-conotoxin ImI. (1994) (168)
- Gamma-carboxyglutamate in a neuroactive toxin. (1984) (162)
- Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum. (2002) (160)
- Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors (2009) (155)
- Pharmacology of α-Conotoxin MII-Sensitive Subtypes of Nicotinic Acetylcholine Receptors Isolated by Breeding of Null Mutant Mice (2007) (152)
- α3β4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons (1999) (149)
- Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine (2011) (145)
- α-RgIA: A Novel Conotoxin That Specifically and Potently Blocks the α9α10 nAChR†,‡ (2006) (144)
- A New Family of Conotoxins That Blocks Voltage-gated Sodium Channels (*) (1995) (143)
- alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. (1995) (143)
- A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors. (1996) (142)
- The Role of α6-Containing Nicotinic Acetylcholine Receptors in Nicotine Reward and Withdrawal (2009) (139)
- Alpha9 nicotinic acetylcholine receptors and the treatment of pain. (2009) (137)
- Involvement of the α3 Subunit in Central Nicotinic Binding Populations (2002) (136)
- Rapid Synaptic Transmission in the Avian Ciliary Ganglion Is Mediated by Two Distinct Classes of Nicotinic Receptors (1997) (133)
- Cholinergic Modulation of Locomotion and Striatal Dopamine Release Is Mediated by α6α4* Nicotinic Acetylcholine Receptors (2010) (132)
- α-Conotoxin PIA Is Selective for α6 Subunit-Containing Nicotinic Acetylcholine Receptors (2003) (130)
- Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues (2007) (122)
- Expression of Nigrostriatal α6-Containing Nicotinic Acetylcholine Receptors Is Selectively Reduced, but Not Eliminated, by β3 Subunit Gene Deletion (2005) (122)
- Long-Term Nicotine Treatment Decreases Striatal α6* Nicotinic Acetylcholine Receptor Sites and Function in Mice (2005) (121)
- Characterization of nicotinic agonist-induced [(3)H]dopamine release from synaptosomes prepared from four mouse brain regions. (2002) (120)
- Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain (2017) (120)
- Striatal α6* Nicotinic Acetylcholine Receptors: Potential Targets for Parkinson's Disease Therapy (2006) (118)
- Nicotine-Mediated Activation of Dopaminergic Neurons in Distinct Regions of the Ventral Tegmental Area (2011) (117)
- Identification of a novel nicotinic binding site in mouse brain using [125I]‐epibatidine (2000) (115)
- Vulnerability of 125I-α-Conotoxin MII Binding Sites to Nigrostriatal Damage in Monkey (2001) (114)
- Neuronal calcium channel inhibitors. Synthesis of omega-conotoxin GVIA and effects on 45Ca uptake by synaptosomes. (1987) (111)
- Alpha7 Nicotinic Acetylcholine Receptors Modulate Motivation to Self-Administer Nicotine: Implications for Smoking and Schizophrenia (2011) (109)
- Cone venom--from accidental stings to deliberate injection. (2001) (109)
- Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway (2009) (109)
- Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers. (1998) (108)
- Determinants of Specificity for α-Conotoxin MII on α3β2 Neuronal Nicotinic Receptors (1997) (107)
- Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the alpha6 subunit. (2004) (107)
- Single-Residue Alteration in α-Conotoxin PnIA Switches Its nAChR Subtype Selectivity† (1999) (106)
- A Novel α-Conotoxin, PeIA, Cloned from Conus pergrandis, Discriminates between Rat α9α10 and α7 Nicotinic Cholinergic Receptors* (2005) (105)
- Chronic Nicotine Differentially Regulates α6- and β3-Containing Nicotinic Cholinergic Receptors in Rat Brain (2007) (103)
- The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. (2003) (102)
- Nigrostriatal Damage Preferentially Decreases a Subpopulation of α6β2* nAChRs in Mouse, Monkey, and Parkinson's Disease Striatum (2007) (101)
- The A-superfamily of Conotoxins (2004) (101)
- Nicotine Persistently Activates Ventral Tegmental Area Dopaminergic Neurons via Nicotinic Acetylcholine Receptors Containing α4 and α6 Subunits (2012) (100)
- α-Conotoxin MII-Sensitive Nicotinic Acetylcholine Receptors in the Nucleus Accumbens Shell Regulate Progressive Ratio Responding Maintained by Nicotine (2010) (99)
- α-Conotoxin BuIA, a Novel Peptide from Conus bullatus, Distinguishes among Neuronal Nicotinic Acetylcholine Receptors* (2005) (98)
- Functional Nicotinic Acetylcholine Receptors Containing α6 Subunits Are on GABAergic Neuronal Boutons Adherent to Ventral Tegmental Area Dopamine Neurons (2011) (98)
- Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist. (2007) (98)
- Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice. (2003) (97)
- Conodipine-M, a Novel Phospholipase A2 Isolated from the Venom of the Marine Snail Conus magus(*) (1995) (97)
- Striatal α5 Nicotinic Receptor Subunit Regulates Dopamine Transmission in Dorsal Striatum (2012) (94)
- α-Conotoxin GIC from Conus geographus, a Novel Peptide Antagonist of Nicotinic Acetylcholine Receptors* (2002) (94)
- Nerve Terminal Nicotinic Acetylcholine Receptors Initiate Quantal GABA Release from Perisomatic Interneurons by Activating Axonal T-Type (Cav3) Ca2+ Channels and Ca2+ Release from Stores (2011) (91)
- α-Conotoxin RgIA protects against the development of nerve injury-induced chronic pain and prevents both neuronal and glial derangement (2014) (90)
- Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms. (2005) (89)
- A Novel Post-translational Modification Involving Bromination of Tryptophan (1997) (89)
- alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. (1995) (88)
- Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues. (2008) (88)
- Nicotinic Receptor-Mediated Reduction in l-DOPA-Induced Dyskinesias May Occur via Desensitization (2010) (86)
- Subunit Composition of Nicotinic Receptors in Monkey Striatum: Effect of Treatments with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine or l-DOPA (2005) (85)
- Isolation and Characterization of a Novel ConusPeptide with Apparent Antinociceptive Activity* (2000) (83)
- Molecular mechanism for analgesia involving specific antagonism of alpha9alpha10 nicotinic acetylcholine receptors. (2006) (82)
- Subtype-selective conopeptides targeted to nicotinic receptors:Concerted discovery and biomedical applications (2008) (81)
- Nicotinic acetylcholine receptors in neuropathic and inflammatory pain (2018) (80)
- α-Conotoxins ImI and ImII (2003) (79)
- Long-Term Nicotine Treatment Differentially Regulates Striatal α6α4β2* and α6(Nonα4)β2* nAChR Expression and Function (2008) (79)
- α-Conotoxins ImI and ImII target distinct regions of the human α7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes (2004) (79)
- Two Distinct Nicotinic Receptors, One Pharmacologically Similar to the Vertebrate α7-Containing Receptor, Mediate Cl Currents inAplysia Neurons (1998) (78)
- Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function. (2003) (78)
- Extending the analysis of nicotinic receptor antagonists with the study of α6 nicotinic receptor subunit chimeras (2008) (78)
- Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors. (2004) (77)
- Nicotine-Induced Dystonic Arousal Complex in a Mouse Line Harboring a Human Autosomal-Dominant Nocturnal Frontal Lobe Epilepsy Mutation (2007) (75)
- Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist (2015) (75)
- Nicotine‐evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage‐gated calcium channels (2001) (74)
- Expression of nigrostriatal alpha 6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by beta 3 subunit gene deletion. (2005) (73)
- alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. (1998) (72)
- Involvement of the alpha3 subunit in central nicotinic binding populations. (2002) (72)
- Functional Nicotinic Acetylcholine Receptors That Mediate Ganglionic Transmission in Cardiac Parasympathetic Neurons (2000) (70)
- Pharmacology of alpha-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice. (2007) (70)
- Chronic nicotine differentially regulates alpha6- and beta3-containing nicotinic cholinergic receptors in rat brain. (2007) (69)
- Conus peptides as probes for ion channels. (1999) (68)
- Phosphocholine – an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors (2016) (67)
- Onset of Cholinergic Efferent Synaptic Function in Sensory Hair Cells of the Rat Cochlea (2011) (66)
- The subunit composition and pharmacology of α-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay (2005) (66)
- Differential Targeting of Nicotinic Acetylcholine Receptors by Novel αA-Conotoxins* (1997) (66)
- Differential Roles of α6β2* and α4β2* Neuronal Nicotinic Receptors in Nicotine- and Cocaine-Conditioned Reward in Mice (2015) (65)
- Varenicline Is a Potent Partial Agonist at α6β2* Nicotinic Acetylcholine Receptors in Rat and Monkey Striatum (2012) (63)
- Pairwise Interactions between Neuronal α7Acetylcholine Receptors and α-Conotoxin PnIB* (2000) (63)
- Loss of α‐conotoxinMII‐ and A85380‐sensitive nicotinic receptors in Parkinson's disease striatum (2004) (63)
- Nicotinic acetylcholine receptors in dorsal root ganglion neurons include the α6β4 subtype (2012) (63)
- The neuronal nicotinic acetylcholine receptors α4* and α6* differentially modulate dopamine release in mouse striatal slices (2008) (63)
- Functional Characterization of α9-Containing Cholinergic Nicotinic Receptors in the Rat Adrenal Medulla: Implication in Stress-Induced Functional Plasticity (2010) (62)
- Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors. (2003) (62)
- Targeting the α9α10 nicotinic acetylcholine receptor to treat severe pain (2007) (61)
- α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. (2010) (61)
- Characterization of Nicotinic Acetylcholine Receptors That Modulate Nicotine-Evoked [3H]Norepinephrine Release from Mouse Hippocampal Synaptosomes (2006) (60)
- Loss of nicotinic receptors in monkey striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment is due to a decline in alpha-conotoxin MII sites. (2002) (59)
- Alpha-conotoxin-ImI: a competitive antagonist at alpha-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons. (1996) (58)
- Reduction of Neuromuscular Activity Is Required for the Rescue of Motoneurons from Naturally Occurring Cell Death by Nicotinic-Blocking Agents (2000) (58)
- Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes (2010) (58)
- The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse (2013) (57)
- Nicotine Improves Cognitive Deficits of Dopamine Transporter Knockout Mice without Long-Term Tolerance (2007) (57)
- Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors. (2013) (55)
- Mouse Striatal Dopamine Nerve Terminals Express α4α5β2 and Two Stoichiometric Forms of α4β2*-Nicotinic Acetylcholine Receptors (2009) (55)
- The α7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions (2015) (55)
- Nicotinic Cholinergic Receptors in the Rat Retina: Simple and Mixed Heteromeric Subtypes (2005) (54)
- The α9α10 nicotinic receptor antagonist α-conotoxin RgIA prevents neuropathic pain induced by oxaliplatin treatment (2016) (54)
- α9‐containing nicotinic acetylcholine receptors and the modulation of pain (2018) (54)
- α6* Nicotinic Acetylcholine Receptor Expression and Function in a Visual Salience Circuit (2012) (54)
- A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. (2005) (53)
- α6β2* and α4β2* Nicotinic Receptors Both Regulate Dopamine Signaling with Increased Nigrostriatal Damage: Relevance to Parkinson's Disease (2010) (53)
- Alpha3beta4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons. (1999) (52)
- Conotoxins: Therapeutic Potential and Application (2006) (52)
- Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation. (2011) (51)
- Habenula cholinergic neurons regulate anxiety during nicotine withdrawal via nicotinic acetylcholine receptors (2016) (51)
- Striatal alpha6* nicotinic acetylcholine receptors: potential targets for Parkinson's disease therapy. (2006) (51)
- UBXD4, a UBX-Containing Protein, Regulates the Cell Surface Number and Stability of α3-Containing Nicotinic Acetylcholine Receptors (2009) (51)
- Nicotine partially protects against paraquat‐induced nigrostriatal damage in mice; link to α6β2* nAChRs (2007) (51)
- Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR. (2006) (51)
- Decrease in α3*/α6* Nicotinic Receptors but Not Nicotine-Evoked Dopamine Release in Monkey Brain after Nigrostriatal Damage (2005) (50)
- Activation of nicotinic acetylcholine receptors increases the frequency of spontaneous GABAergic IPSCs in rat basolateral amygdala neurons. (2005) (50)
- α-Conotoxin OmIA Is a Potent Ligand for the Acetylcholine-binding Protein as Well as α3β2 and α7 Nicotinic Acetylcholine Receptors* (2006) (50)
- Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10 (2017) (48)
- Isolation of Lys-conopressin-G from the venom of the worm-hunting snail, Conus imperialis. (1994) (48)
- A Novel Inhibitor of α9α10 Nicotinic Acetylcholine Receptors from Conus vexillum Delineates a New Conotoxin Superfamily (2013) (48)
- RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia (2017) (47)
- 5‐Iodo‐A‐85380 binds to α‐conotoxin MII‐sensitive nicotinic acetylcholine receptors (nAChRs) as well as α4β2* subtypes (2002) (47)
- Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors (2004) (46)
- Differential Regulation of Mesolimbic α3*/α6β2* and α4β2* Nicotinic Acetylcholine Receptor Sites and Function after Long-Term Oral Nicotine to Monkeys (2006) (46)
- Declines in Different β2* Nicotinic Receptor Populations in Monkey Striatum after Nigrostriatal Damage (2002) (46)
- Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors* (2012) (46)
- Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors. (1999) (45)
- Cholinergic nicotinic receptor involvement in movement disorders associated with Lewy body diseases. An autoradiography study using [125I]α-conotoxinMII in the striatum and thalamus (2005) (45)
- Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior (2012) (45)
- Cotinine Selectively Activates a Subpopulation of α3/α6β2* Nicotinic Receptors in Monkey Striatum (2008) (44)
- α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats (2013) (44)
- Increases in α4* but not α3*/α6* nicotinic receptor sites and function in the primate striatum following chronic oral nicotine treatment (2006) (43)
- A sleep-inducing peptide from Conus geographus venom. (1985) (43)
- Nicotine-mediated improvement in l-dopa-induced dyskinesias in MPTP-lesioned monkeys is dependent on dopamine nerve terminal function (2013) (42)
- Effect of Novel α-Conotoxins on Nicotine-Stimulated [3H]Dopamine Release from Rat Striatal Synaptosomes (2005) (42)
- Pharmacologically Distinct Nicotinic Acetylcholine Receptors Drive Efferent-Mediated Excitation in Calyx-Bearing Vestibular Afferents (2015) (41)
- Three-Dimensional Solution Structure of α-Conotoxin MII, an α3β2 Neuronal Nicotinic Acetylcholine Receptor-Targeted Ligand†,‡ (1997) (41)
- Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo. (2012) (40)
- N,N′-Alkane-diyl-bis-3-picoliniums as Nicotinic Receptor Antagonists: Inhibition of Nicotine-Evoked Dopamine Release and Hyperactivity (2008) (40)
- Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells. (2011) (40)
- Prominent Role of α3/α6β2* nAChRs in Regulating Evoked Dopamine Release in Primate Putamen: Effect of Long-Term Nicotine Treatment (2009) (39)
- Long-Term Nicotine Exposure Depresses Dopamine Release in Nonhuman Primate Nucleus Accumbens (2012) (39)
- Neuronal-type acetylcholine receptors and regulation of alpha 7 gene expression in vertebrate skeletal muscle. (1997) (39)
- MicroO-conotoxin MrVIA inhibits mammalian sodium channels, but not through site I. (1996) (39)
- ABT‐089 and ABT‐894 reduce levodopa‐induced dyskinesias in a monkey model of Parkinson's disease (2014) (39)
- Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors* (2013) (39)
- The Antinociceptive Effects of Nicotinic Partial Agonists Varenicline and Sazetidine-A in Murine Acute and Tonic Pain Models (2012) (39)
- Conus peptides: novel probes for nicotinic acetylcholine receptor structure and function. (2000) (38)
- Role for α6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice (2012) (38)
- Compensation in pre‐synaptic dopaminergic function following nigrostriatal damage in primates (2006) (38)
- Amino Acid Residues That Confer High Selectivity of the α6 Nicotinic Acetylcholine Receptor Subunit to α-Conotoxin MII[S4A,E11A,L15A]* (2008) (38)
- The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies (2014) (38)
- αConotoxin Arenatus IB[V11L,V16D] Is a Potent and Selective Antagonist at Rat and Human Native α7 Nicotinic Acetylcholine Receptors (2008) (38)
- α4α6β2* Nicotinic Acetylcholine Receptor Activation on Ventral Tegmental Area Dopamine Neurons Is Sufficient to Stimulate a Depolarizing Conductance and Enhance Surface AMPA Receptor Function (2013) (37)
- C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation (2018) (37)
- Determinants of specificity for alpha-conotoxin MII on alpha3beta2 neuronal nicotinic receptors. (1997) (36)
- Synthesis and Characterization of 125I-α-Conotoxin ArIB[V11L;V16A], a Selective α7 Nicotinic Acetylcholine Receptor Antagonist (2008) (36)
- Molecular Interaction of α-Conotoxin RgIA with the Rat α9α10 Nicotinic Acetylcholine Receptor (2015) (36)
- Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons. (2013) (35)
- Localized low‐level re‐expression of high‐affinity mesolimbic nicotinic acetylcholine receptors restores nicotine‐induced locomotion but not place conditioning (2009) (35)
- Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors. (2005) (35)
- α6β2*‐subtype nicotinic acetylcholine receptors are more sensitive than α4β2*‐subtype receptors to regulation by chronic nicotine administration (2014) (35)
- α-Conotoxin PeIA[S9H,V10A,E14N] Potently and Selectively Blocks α6β2β3 versus α6β4 Nicotinic Acetylcholine Receptors (2012) (34)
- Comparative functional expression of nAChR subtypes in rodent DRG neurons (2013) (34)
- Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation (2014) (33)
- Loss of alpha-conotoxinMII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum. (2004) (33)
- Photoactivatable drugs for nicotinic optopharmacology (2018) (33)
- Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation (2007) (32)
- Sustained increase of alpha7 nicotinic receptors and choline-induced improvement of learning deficit in STOP knock-out mice (2007) (32)
- Striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6‐nicotinic receptor control in nucleus accumbens (2013) (32)
- Inhibition of nicotine-induced hippocampal norepinephrine release in rats by alpha-conotoxins MII and AuIB microinjected into the locus coeruleus (1999) (32)
- Ventral tegmental area α6β2 nicotinic acetylcholine receptors modulate phasic dopamine release in the nucleus accumbens core (2013) (32)
- Acute Ethanol Inhibits Dopamine Release in the Nucleus Accumbens via α6 Nicotinic Acetylcholine Receptors (2014) (31)
- Solution Conformation of α-Conotoxin EI, a Neuromuscular Toxin Specific for the α1/δ Subunit Interface of Torpedo Nicotinic Acetylcholine Receptor* (2001) (31)
- Nicotine partially protects against paraquat-induced nigrostriatal damage in mice; link to alpha6beta2* nAChRs. (2007) (31)
- α-Conotoxin imperialis I inhibits nicotine-evoked hormone release and cell proliferation in human neuroendocrine carcinoma cells (1996) (31)
- Characterization of [125I]epibatidine binding and nicotinic agonist‐mediated 86Rb+ efflux in interpeduncular nucleus and inferior colliculus of β2 null mutant mice (2002) (31)
- Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1. (2014) (30)
- Receptor subtypes mediating depressor responses to microinjections of nicotine into medial NTS of the rat. (2000) (30)
- The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic. (2011) (30)
- John Daly’s Compound, Epibatidine, Facilitates Identification of Nicotinic Receptor Subtypes (2009) (30)
- Differential nicotinic receptor expression in monkey basal ganglia: Effects of nigrostriatal damage (2002) (30)
- Identification of Residues That Confer α-Conotoxin-PnIA Sensitivity on the α3 Subunit of Neuronal Nicotinic Acetylcholine Receptors (2003) (30)
- Conopeptides [V11L;V16D]ArIB and RgIA4: Powerful Tools for the Identification of Novel Nicotinic Acetylcholine Receptors in Monocytes (2019) (29)
- Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission (2018) (29)
- Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain. (2011) (29)
- Enhanced synthesis and release of dopamine in transgenic mice with gain‐of‐function α6* nAChRs (2014) (28)
- bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse (2011) (28)
- Characterization of nicotinic receptors inducing noradrenaline release and absence of nicotinic autoreceptors in human neocortex (2004) (28)
- Nicotine regulates activity of lateral habenula neurons via presynaptic and postsynaptic mechanisms (2016) (28)
- Novel Small Molecule &agr;9&agr;10 Nicotinic Receptor Antagonist Prevents and Reverses Chemotherapy-Evoked Neuropathic Pain in Rats (2012) (28)
- Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain (2019) (28)
- Ca2+ changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals (2001) (27)
- Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors[S] (2017) (27)
- Nuclear Magnetic Resonance Solution Conformation of α-Conotoxin AuIB, an α3β4 Subtype-selective Neuronal Nicotinic Acetylcholine Receptor Antagonist* (2000) (27)
- Partial Recovery of Striatal Nicotinic Receptors in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Lesioned Monkeys with Chronic Oral Nicotine (2006) (27)
- Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor β subunit (2006) (27)
- A novel fluorescent α‐conotoxin for the study of α7 nicotinic acetylcholine receptors (2009) (27)
- αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype (2017) (26)
- Long‐term nicotine treatment down‐regulates α6β2* nicotinic receptor expression and function in nucleus accumbens (2013) (26)
- Native α6β4∗ nicotinic receptors control exocytosis in human chromaffin cells of the adrenal gland (2012) (26)
- α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. (2017) (26)
- Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library (2014) (26)
- Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors (2015) (26)
- L-DOPA treatment modulates nicotinic receptors in monkey striatum. (2003) (25)
- Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes. (2004) (25)
- Peptides from Conus Venoms which Affect Ca++ Entry into Neurons (1990) (25)
- Decrease in alpha3*/alpha6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostriatal damage. (2005) (25)
- Differential regulation of mesolimbic alpha 3/alpha 6 beta 2 and alpha 4 beta 2 nicotinic acetylcholine receptor sites and function after long-term oral nicotine to monkeys. (2006) (25)
- Alpha-conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors. (2002) (25)
- I-a-Conotoxin MII Identifies a Novel Nicotinic Acetylcholine Receptor Population in Mouse Brain (2000) (25)
- Spinal α3β2* nicotinic acetylcholine receptors tonically inhibit the transmission of nociceptive mechanical stimuli (2008) (25)
- Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function (2013) (25)
- HIV gp120 Induces Mucus Formation in Human Bronchial Epithelial Cells through CXCR4/α7-Nicotinic Acetylcholine Receptors (2013) (25)
- α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells (2015) (24)
- αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors. (2015) (24)
- Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites. (2003) (24)
- The nicotine‐mediated decline in l‐dopa‐induced dyskinesias is associated with a decrease in striatal dopamine release (2013) (24)
- Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors (2018) (24)
- Increases in alpha4* but not alpha3*/alpha6* nicotinic receptor sites and function in the primate striatum following chronic oral nicotine treatment. (2006) (24)
- Prenatal nicotine exposure alters the nicotinic receptor subtypes that modulate excitation of parasympathetic cardiac neurons in the nucleus ambiguus from primarily α3β2 and/or α6βX to α3β4 (2006) (24)
- Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells (2017) (24)
- Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain. (2007) (24)
- Carboxyglutamate in a Neuroactive Toxin (24)
- α –RgIA, a Novel Conotoxin that Blocks the α 9 α 10 nAChR: Structure and Identification of Key Receptor Binding Residues (2008) (23)
- α6 nAChR subunit residues that confer α‐conotoxin BuIA selectivity (2012) (23)
- Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research (2020) (23)
- α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity (2015) (23)
- Complex patterns of [125I]omega-conotoxin GVIA binding site expression during postnatal rat brain development. (1994) (23)
- Composition and therapeutic utility of conotoxins from genus Conus. Patent status 1996 - 2000 (2001) (22)
- Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice. (2002) (22)
- α7 nicotinic receptor agonists reduce levodopa‐induced dyskinesias with severe nigrostriatal damage (2015) (22)
- Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction (2018) (22)
- Nicotine Reduces Antipsychotic-Induced Orofacial Dyskinesia in Rats (2012) (22)
- 5-Iodo-A-85380 binds to alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors (nAChRs) as well as alpha4beta2* subtypes. (2002) (22)
- Differential block of nicotinic synapses on B versus C neurones in sympathetic ganglia of frog by α‐conotoxins MII and ImI (1997) (22)
- Varenicline enhances dopamine release facilitation more than nicotine after long-term nicotine treatment and withdrawal (2014) (22)
- Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra (2017) (22)
- Involvement of α6/α3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy bodies: [125I]-α-conotoxin MII binding in the thalamus and striatum. (2004) (21)
- NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold. (2006) (21)
- Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype selectivity. (1999) (21)
- Chronic treatment with varenicline changes expression of four nAChR binding sites in mice (2015) (21)
- Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors. (2004) (20)
- Abolishment of serotonergic neurotransmission to cardiac vagal neurons during and after hypoxia and hypercapnia with prenatal nicotine exposure. (2009) (20)
- Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan. (2018) (19)
- Presence of serotonin in the venom of Conus imperialis. (1993) (19)
- Chronic Nicotine Treatment Increases nAChRs and Microglial Expression in Monkey Substantia Nigra After Nigrostriatal Damage (2009) (19)
- Erratum: Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: Disproportionate increase of the α6 subunit (Molecular Pharmacology (2004) 65 (611-622)) (2004) (19)
- Alpha6-containing nicotinic acetylcholine receptor is a highly sensitive target of alcohol (2019) (18)
- Key Residues in the Nicotinic Acetylcholine Receptor β2 Subunit Contribute to α-Conotoxin LvIA Binding* (2015) (18)
- Nicotine Dependence Reveals Distinct Responses from Neurons and Their Resident Nicotinic Receptors in Medial Habenula (2015) (18)
- A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties (2015) (18)
- Determinants of potency on alpha-conotoxin MII, a peptide antagonist of neuronal nicotinic receptors. (2004) (17)
- Assessment of the expression and role of the α1-nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea. (2016) (17)
- Localization of [125I]ω-conotoxin GVIA binding in human hippocampus and cerebellum (1993) (17)
- RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats (2019) (17)
- Pharmacological characterization of native α7 nicotinic ACh receptors and their contribution to depolarization‐elicited exocytosis in human chromaffin cells (2012) (16)
- r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement (2015) (16)
- Evidence for a role for α6∗ nAChRs in l-dopa-induced dyskinesias using parkinsonian α6∗ nAChR gain-of-function mice (2015) (16)
- Iodo-α-conotoxin MI selectively binds the α/δ subunit interface of muscle nicotinic acetylcholine receptors (2004) (15)
- Solution Conformation of αA-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus* (2003) (15)
- α6β2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty (2017) (15)
- Synthesis of Fluorescent Analogs of α-Conotoxin MII (2006) (15)
- Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. (2010) (15)
- SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player (2019) (15)
- Characterization of nicotinic acetylcholine receptors in cultured arterial chemoreceptor cells of the cat (2003) (15)
- Pairwise interactions between neuronal alpha(7) acetylcholine receptors and alpha-conotoxin PnIB. (2000) (15)
- Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes (2006) (14)
- Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors. (2006) (14)
- Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release. (2011) (14)
- Nigrostriatal Damage Preferentially Decreases a Subpopulation of (cid:1) 6 (cid:2) 2* nAChRs in Mouse, Monkey, and Parkinson’s Disease Striatum (2007) (14)
- Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: Role of nicotinic acetylcholine receptors (2015) (13)
- α4β2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion (2011) (13)
- Limited Efficacy of α-Conopeptides, Vc1.1 and RgIA, To Inhibit Sensory Neuron CaV Current,, (2015) (13)
- A novel α‐conotoxin MII‐sensitive nicotinic acetylcholine receptor modulates [3H]‐GABA release in the superficial layers of the mouse superior colliculus (2012) (13)
- Efferent Synaptic Transmission at the Vestibular Type II Hair Cell Synapse. (2020) (13)
- Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain (2017) (12)
- Paraquat Exposure Reduces Nicotinic Receptor-Evoked Dopamine Release in Monkey Striatum (2008) (12)
- Dopamine release in human neocortical slices: Characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release (2006) (12)
- Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor. (2001) (11)
- Selective recovery of striatal 125I-α-conotoxinmii nicotinic receptors after nigrostriatal damage in monkeys (2004) (11)
- Identification of residues that confer alpha-conotoxin-PnIA sensitivity on the alpha 3 subunit of neuronal nicotinic acetylcholine receptors. (2003) (11)
- Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors (2018) (11)
- Structural basis for alpha-conotoxin potency and selectivity. (2009) (11)
- Human nicotinic receptors in chromaffin cells: characterization and pharmacology (2017) (11)
- β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells (2018) (11)
- Rapid multi-directed cholinergic transmission in the central nervous system (2021) (11)
- Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors (2005) (10)
- α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors (2019) (10)
- Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells (2018) (10)
- Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain. (2021) (10)
- Prenatal nicotine exposure alters the nicotinic receptor subtypes that modulate excitation of parasympathetic cardiac neurons in the nucleus ambiguus from primarily alpha3beta2 and/or alpha6betaX to alpha3beta4. (2006) (10)
- Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism. (2021) (10)
- CHAPTER 6:The Molecular Diversity of Conoidean Venom Peptides and their Targets: From Basic Research to Therapeutic Applications (2015) (10)
- Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits (2015) (10)
- Localization of [125I]omega-conotoxin GVIA binding in human hippocampus and cerebellum. (1993) (9)
- Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors. (2020) (9)
- Expression of α3β2β4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists (2020) (9)
- PeIA-5466: A novel peptide antagonist containing non-natural amino acids that selectively targets α3β2 nicotinic acetylcholine receptors. (2019) (9)
- Pharmacological and functional comparisons of α6/α3β2β3-nAChRs and α4β2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line (2018) (9)
- Determinants of alpha-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit. (2006) (9)
- Functional properties of neuronal nicotinic acetylcholine receptors in the chick retina during development (2005) (9)
- Toxin antagonists of the neuronal nicotinic acetylcholine receptor (2000) (9)
- Monkey Adrenal Chromaffin Cells Express α6β4* Nicotinic Acetylcholine Receptors (2014) (9)
- Neuronal nicotinic acetylcholine receptors mediate ∆9‐THC dependence: Mouse and human studies (2018) (8)
- MS based scanning methodologies applied to Conus venom (1995) (8)
- Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs. (2021) (8)
- Iodo-alpha-conotoxin MI selectively binds the alpha/delta subunit interface of muscle nicotinic acetylcholine receptors. (2004) (8)
- Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP (2022) (8)
- Diverse strategies targeting alpha 7 homomeric and alpha 6 beta 2 * heteromeric nicotinic acetylcholine receptors for smoking cessation (2014) (8)
- Involvement of alpha6/alpha3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy bodies: [(125)I]-alpha-conotoxin MII binding in the thalamus and striatum. (2004) (8)
- An alpha4beta4 nicotinic receptor subtype is present in chick retina: identification, characterization and pharmacological comparison with the transfected alpha4beta4 and alpha6beta4 subtypes. (2001) (8)
- Gene editing vectors for studying nicotinic acetylcholine receptors in cholinergic transmission (2018) (7)
- αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish (2020) (7)
- Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors. (2020) (7)
- Amyloid Beta Peptide (Aβ1-42) Reverses the Cholinergic Control of Monocytic IL-1β Release (2020) (7)
- Autoradiographic localization of the binding of calcium channel antagonist, [125I]ω-agatoxin IIIA, in rat brain (1992) (6)
- a-Conotoxin Au I B Selectively Blocks a 3 b 4 Nicotinic Acetylcholine Receptors and Nicotine-Evoked Norepinephrine Release (1998) (6)
- Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors. (2005) (6)
- Functional Expression of Human α9* Nicotinic Acetylcholine Receptors in X. laevis Oocytes Is Dependent on the α9 Subunit 5′ UTR (2013) (6)
- Rapid ‘multi-directed’ cholinergic transmission at central synapses (2020) (6)
- Fast synaptic transmission in the goldfish CNS mediated by multiple nicotinic receptors (2011) (5)
- Three-dimensional solution structure of alpha-conotoxin MII, an alpha3beta2 neuronal nicotinic acetylcholine receptor-targeted ligand. (1997) (5)
- Determinants of Specificity for a-Conotoxin MII on a 3 b 2 Neuronal Nicotinic Receptors (1997) (5)
- Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes. (2006) (5)
- Nuclear magnetic resonance solution conformation of alpha-conotoxin AuIB, an alpha(3)beta(4) subtype-selective neuronal nicotinic acetylcholine receptor antagonist. (2000) (4)
- Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells (2021) (4)
- Alkaloid ligands enable function of homomeric human α10 nicotinic acetylcholine receptors (2022) (4)
- RgIA4 Prevention of Acute Oxaliplatin-Induced Cold Allodynia Requires α9-Containing Nicotinic Acetylcholine Receptors and CD3+ T-Cells (2022) (4)
- Prior nicotine self-administration attenuates subsequent dopaminergic deficits of methamphetamine in rats: role of nicotinic acetylcholine receptors (2016) (4)
- Nicotinic acetylcholine receptor channels in cat chemoreceptor cells. (2003) (3)
- Efferent Synaptic Transmission at the Vestibular Type II Hair Cell Synapse (2020) (3)
- Solution conformation of α -conotoxin GIC, a novel potent antagonist of α 3 β 2 nicotinic acetylcholine receptors (2004) (3)
- Synthesis of fluorescent analogs of alpha-conotoxin MII. (2006) (3)
- Conus Peptides and Their Iodinated Derivatives as Probes for Ion Channels and Receptors (2000) (3)
- Nicotinic Acetylcholine Receptor Partial Antagonist Polyamides from Tunicates and Their Predatory Sea Slugs. (2021) (3)
- An a 4 b 4 Nicotinic Receptor Subtype Is Present in Chick Retina: Identification, Characterization and Pharmacological Comparison with the Transfected a 4 b 4 and a 6 b 4 Subtypes (2001) (2)
- Application of alpha1-antitrypsin in a rat model of veno-arterial extracorporeal membrane oxygenation (2021) (2)
- GZ556A and ZZ204G are novel small molecule antagonists of α9α10 nAChRs and are analgesic in rats (2009) (2)
- Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens (2023) (2)
- Is a Potent and Selective Antagonist at Rat and Human Native 7 Nicotinic Acetylcholine Receptors (2008) (2)
- Indolizidine ( − )-235 B ′ and related structural analogs : Discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [ 3 H ] dopamine release (2011) (1)
- Cross Talk between α7 and α3β4 Nicotinic Receptors Prevents Their Desensitization in Human Chromaffin Cells (2021) (1)
- Chronic nicotine treatment differentially regulates striatal α 6 α 4 β 2 * and α 6 ( non α 4 ) β 2 * nAChR expression and function (2008) (1)
- Limited Efficacy of #-Conopeptides , Vc 1 . 1 and RgIA , to Inhibit Sensory Neuron CaV Current Minimal CaV Current Effect by Vc 1 . 1 and RgIA (2015) (1)
- Synthesis and characterization of [ 125 I] α -conotoxin ArIB[V11L;V16A], a selective α 7 nAChR antagonist. (2008) (1)
- Chronic nicotine treatment decreases striatal α 6* nAChR sites and function in mice (2005) (1)
- Therapeutic concentrations of varenicline increases exocytotic release of catecholamines from human and rat adrenal chromaffin cells in the presence of nicotine (2021) (1)
- Labeling α7 nAChRs on hippocampal neurons using fluorescent analogs of α-conotoxin ArIB[V11L;V16A] (2009) (1)
- Nicotinic cholinergic receptors in dorsal root ganglion neurons include the α6β4* subtype (2011) (1)
- Nicotinic acetylcholine receptors: therapeutic targets for novel ligands to treat pain and inflammation. (2023) (1)
- Author Correction: Rapid multi-directed cholinergic transmission in the central nervous system (2021) (0)
- LIGANDS TARGETING α10 RECEPTORS TO INHIBIT NEOROPATHIC PAIN (2022) (0)
- Amyloid beta peptide (Aβ1–42) antagonizes nicotinic acetylcholine receptors of monocytes and enables ATP‐mediated release of interleukin‐1β (2021) (0)
- α6* nAChR expression and function in brain areas influencing DA transmission probed with α6-GFP transgenic mice (2011) (0)
- Nicotinic acetylcholine receptor regulation of striatal dopamine transmission: The different requirement for diverse subtypes in ventral versus dorsal striatum (2013) (0)
- Decrease in (cid:1) 3*/ (cid:1) 6* Nicotinic Receptors but Not Nicotine-Evoked Dopamine Release in Monkey Brain after Nigrostriatal Damage (2005) (0)
- Novel α-CTx TxIB Selectively Blocks α 6 / α 3 β 2 β 3 nAChRs 1 Characterization of a Novel α-Conotoxin from Conus textile that Selectively Targets α 6 / α 3 β 2 β 3 Nicotinic Acetylcholine Receptors (2012) (0)
- JPET # 194084 2 RUNNING TITLE PAGE Running Title : Long-term nicotine depresses dopamine release (2012) (0)
- Conotoxines riches en $g(y)-carboxyglutamate lineaire (2002) (0)
- Identification of Residues That Confer (cid:1) -Conotoxin-PnIA Sensitivity on the (cid:1) 3 Subunit of Neuronal Nicotinic Acetylcholine Receptors (2003) (0)
- Molecular determinants of (cid:2) -conotoxin potency for inhibition of human and rat (cid:2) 6 (cid:3) 4 nicotinic acetylcholine receptors (2020) (0)
- Human nicotinic receptors in chromaffin cells: characterization and pharmacology (2017) (0)
- ArIB(V11L;V16A), a Selective 7 Nicotinic Acetylcholine Receptor Antagonist □ S (2008) (0)
- Molecular Interaction of a-Conotoxin RgIA with the Rat a 9 a 10 Nicotinic Acetylcholine Receptor s (2016) (0)
- Full activation of an α7-α3β4 nicotinic receptor complex avoids receptor desensitization in human chromaffin cells (2020) (0)
- Cotinine Selectively Activates a Subpopulation of (cid:1) 3/ (cid:1) 6 (cid:2) 2* Nicotinic Receptors in Monkey Striatum (2008) (0)
- Molecular Subunit Composition of Functional Nicotinic Receptors in Dopaminergic Neurons Investigated with Knock-Out Mice (2010) (0)
- Expression of Nigrostriatal (cid:1) 6-Containing Nicotinic Acetylcholine Receptors Is Selectively Reduced, but Not Eliminated, by (cid:2) 3 Subunit Gene Deletion (2005) (0)
- a 4 b 2 Nicotinic Acetylcholine Receptors in the Early Postnatal Mouse Superior Cervical Ganglion (2011) (0)
- Nicotinic acetylcholine receptor partial antagonist polyamides from tunicates and their predatory sea slugs (2021) (0)
- Mutation of proline enables subtype selectivity of α-conotoxin BuIA (2009) (0)
- α‐Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between 06 β4 and 0:6 β2 nicotinic acetylcholine receptors and blocks nicotine‐stimulated norepinephrine release (2010) (0)
- A novel (cid:1) 4/7-conotoxin LvIA from Conus lividus that selectively blocks (cid:1) 3 (cid:2) 2 vs . (cid:1) 6/ (cid:1) 3 (cid:2) 2 (cid:2) 3 nicotinic acetylcholine receptors (2014) (0)
- An a 4 b 4 Nicotinic Receptor Subtype Is Present in Chick Retina: Identification, Characterization and Pharmacological Comparison with the Transfected a 4 b 4 and a 6 b 4 Subtypes (2001) (0)
- {alpha}3 and not {alpha}6 subunit containing nAChR mediate cardiac cholinergic ganglionic transmission (2006) (0)
- Novel nicotinic receptor ligands (1994) (0)
- Ventral tegmental area α6β2 nicotinic acetylcholine receptors modulate phasic dopamine release in the nucleus accumbens core (2013) (0)
- A novel α-conotoxin, ArIB, is a potent ligand selective for α7 nicotinic acetylcholine receptors (2007) (0)
- CrucialRoleof4and6NicotinicAcetylcholineReceptor SubunitsfromVentralTegmentalAreainSystemicNicotine Self-Administration (2008) (0)
- r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement (2015) (0)
- Nicotine, Methamphetamine‐Induced Dopaminergic Deficits, and the Impact on α4β2 and α6β2 Nicotinic Receptors (2015) (0)
- IPSCs in Rat Basolateral Amygdala Neurons Increases the Frequency of Spontaneous GABAergic Activation of Nicotinic Acetylcholine Receptors (2005) (0)
- Chronic Nicotine Exposure Depresses Dopamine Release in Nonhuman Primate Nucleus Accumbens (2012) (0)
- channels in identified muscle afferent neurons Tetrodotoxin-resistant voltage-dependent sodium (2015) (0)
- Pharmacological and functional comparisons of α6/α3β2β3-nAChRs and α4β2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line (2018) (0)
- C including dopamine neuron degeneration , suggesting that the nicotine in tobacco may underlie the reduced incidence of Parkinson ' s disease in smokers ( (2014) (0)
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