J. Michael Wilson

Q: What Schools Are Affiliated With J. Michael Wilson

J. Michael Wilson is affiliated with the following schools: University of Oxford, University of Michigan, University of Pennsylvania

J. Michael Wilson's AcademicInfluence.com Rankings

J. Michael Wilson

Biology

#7617

World Rank

#10566

Historical Rank

Virology

#160

World Rank

#165

Historical Rank

Immunology

#414

World Rank

#430

Historical Rank

biology Degrees

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Biology

J. Michael Wilson's Degrees

PhD Immunology Stanford University
Doctorate Medicine University of California, San Francisco

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J. Michael Wilson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. (1994) (1685)
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses (1995) (1115)
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. (1998) (773)
Immune responses to adenovirus and adeno-associated virus in humans (1999) (692)
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. (1994) (656)
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. (1994) (655)
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. (1998) (601)
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis (1996) (572)
Adenoviruses as gene-delivery vehicles. (1996) (487)
Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus. (1997) (474)
Gene therapy: adenovirus vectors. (1993) (434)
Cathelicidins - a family of multifunctional antimicrobial peptides (2003) (410)
Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. (1996) (406)
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. (2001) (399)
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy (1996) (386)
Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. (2001) (384)
Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response. (1990) (383)
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. (2001) (354)
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. (1998) (347)
Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits. (1991) (346)
Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. (1993) (336)
The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment. (1993) (335)
Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. (1991) (334)
Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. (2001) (330)
Implantation of vascular grafts lined with genetically modified endothelial cells. (1989) (326)
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis. (1996) (316)
Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. (1994) (311)
Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. (2001) (307)
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. (1994) (305)
Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. (1999) (304)
Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo. (1995) (303)
The origin, mechanisms, incidence and clinical consequences of chromosomal mosaicism in humans. (2014) (290)
Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs (1996) (289)
A newly discovered bacterium associated with parthenogenesis and a change in host selection behavior in parasitoid wasps (2001) (284)
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. (1995) (283)
Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. (1989) (270)
Replication-Defective Vector Based on a Chimpanzee Adenovirus (2001) (268)
Expression of the cystic fibrosis gene in adult human lung. (1994) (262)
A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier. (1996) (261)
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. (1999) (256)
A possible role for kinase-associated protein phosphatase in the Arabidopsis CLAVATA1 signaling pathway. (1997) (242)
Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a. (1994) (226)
Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease (1996) (224)
Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits. (1992) (219)
The innate immune system in cystic fibrosis lung disease. (1999) (218)
Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer. (1997) (206)
Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. (1999) (204)
Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study. (1993) (201)
EEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblasts. (2000) (200)
Adenoviral-mediated gene transfer to rabbit synovium in vivo. (1993) (198)
Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. (1998) (196)
Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway (1995) (195)
Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues (1996) (195)
Efficacy and safety of adeno‐associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy (2007) (193)
High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus. (1998) (191)
Long-term regulated expression of growth hormone in mice after intramuscular gene transfer. (1999) (186)
Transcriptional repression by Msx-1 does not require homeodomain DNA-binding sites (1995) (179)
Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo. (2000) (176)
Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung. (1996) (174)
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. (1994) (173)
Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells. (1995) (172)
Immunology of gene therapy with adenoviral vectors in mouse skeletal muscle. (1996) (163)
In vivo expression of full-length human dystrophin from adenoviral vectors deleted of all viral genes. (1996) (159)
Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver. (1996) (152)
Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding. (1994) (149)
Tailoring the AAV vector capsid for gene therapy (2009) (147)
A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis. (1999) (147)
Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers (1996) (145)
Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. (1988) (143)
Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice. (1998) (143)
Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria. (1997) (142)
An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer. (1993) (142)
Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. (2001) (139)
Hypoxanthine-guanine phosphoribosyltransferase deficiency. The molecular basis of the clinical syndromes. (1983) (136)
Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. (2000) (134)
Gene transfer into the liver of nonhuman primates with E1-deleted recombinant adenoviral vectors: safety of readministration. (1999) (130)
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. (1994) (130)
Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial. (1996) (130)
Retrovirus-mediated transduction of adult hepatocytes. (1988) (126)
Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B. (1991) (124)
Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. (1990) (122)
Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors. (2000) (121)
Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts. (1994) (121)
Lentiviral vectors for gene therapy of cystic fibrosis. (1997) (120)
Oral Vaccination of Mice with Adenoviral Vectors Is Not Impaired by Preexisting Immunity to the Vaccine Carrier (2003) (117)
Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naïve and pre-immunized mice (2005) (116)
Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity. (2001) (114)
Genotype spectrum of ornithine transcarbamylase deficiency: correlation with the clinical and biochemical phenotype. (2000) (112)
Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments. (2000) (110)
Safety and feasibility of liver-directed ex vivo gene therapy for homozygous familial hypercholesterolemia. (1996) (110)
Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium. (2000) (104)
Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. (1993) (102)
Chimpanzee-origin adenovirus vectors as vaccine carriers (2006) (99)
A molecular survey of hypoxanthine-guanine phosphoribosyltransferase deficiency in man. (1986) (99)
A possible nucleotide-binding domain in the tertiary fold of phosphoribosyltransferases. (1983) (98)
Rescue of skeletal muscles of gamma-sarcoglycan-deficient mice with adeno-associated virus-mediated gene transfer. (2000) (98)
Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells. (1990) (97)
Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial. (1994) (97)
Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy. (2003) (96)
A novel adenovirus-adeno-associated virus hybrid vector that displays efficient rescue and delivery of the AAV genome. (1996) (95)
Gene therapy for cystic fibrosis: challenges and future directions. (1995) (93)
Transplantation of genetically modified autologous hepatocytes into nonhuman primates: feasibility and short-term toxicity. (1992) (92)
In vivo retroviral gene transfer into human bronchial epithelia of xenografts. (1992) (92)
Human Immunodeficiency Virus Type 1-Specific Immune Responses in Primates upon Sequential Immunization with Adenoviral Vaccine Carriers of Human and Simian Serotypes (2004) (91)
Adhesion and incorporation of lacZ-transduced endothelial cells into the intact capillary wall in the rat. (1992) (90)
Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study. (1995) (90)
A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors. (2001) (87)
A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes. (1992) (87)
Methods of gene delivery. (1998) (85)
Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR. (1993) (84)
Phase I clinical trial utilizing gene therapy for limb girdle muscular dystrophy: alpha-, beta-, gamma-, or delta-sarcoglycan gene delivered with intramuscular instillations of adeno-associated vectors. (2000) (82)
A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence (2009) (78)
Mismatch repair of cis-diamminedichloroplatinum(II)-induced DNA damage. (1985) (76)
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9 (2011) (74)
Human gene marker/therapy clinical protocols. (1996) (73)
Dopamine D2 and D4 receptor ligands: relation to antipsychotic action. (1998) (72)
Adenoviral RB2/p130 gene transfer inhibits smooth muscle cell proliferation and prevents restenosis after angioplasty. (1999) (71)
Single-Dose Protection against Plasmodium berghei by a Simian Adenovirus Vector Using a Human Cytomegalovirus Promoter Containing Intron A (2008) (71)
The Glucokinase Glucose Sensor in Human Pancreatic Islet Tissue (1986) (70)
Characterization of acquired resistance to cis-diamminedichloroplatinum (II) in BE human colon carcinoma cells. (1990) (68)
Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemann-Pick disease type C. (1997) (67)
Evaluating the potential of germ line transmission after intravenous administration of recombinant adenovirus in the C3H mouse. (1998) (66)
Identification of the murine firefly luciferase-specific CD8 T-cell epitopes (2009) (64)
Intracranial administration of adenovirus expressing HSV-TK in combination with ganciclovir produces a dose-dependent, self-limiting inflammatory response. (1997) (64)
Analysis of acetaminophen metabolites in urine by high-performance liquid chromatography with UV and amperometric detection. (1982) (64)
Human hypoxanthine (guanine) phosphoribosyltransferase: an amino acid substitution in a mutant form of the enzyme isolated from a patient with gout. (1983) (62)
Human hypoxanthine-guanine phosphoribosyltransferase. Demonstration of structural variants in lymphoblastoid cells derived from patients with a deficiency of the enzyme. (1982) (62)
Reconstitution of tracheal grafts with a genetically modified epithelium. (1991) (62)
Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbits. (1996) (60)
The transmembrane domain of diphtheria toxin improves molecular conjugate gene transfer. (1997) (60)
Treatment of recurrent or progressive malignant glioma with a recombinant adenovirus expressing human interferon-beta (H5.010CMVhIFN-beta): a phase I trial. (2001) (59)
Comparison of aneuploidy, pregnancy and live birth rates between day 5 and day 6 blastocysts. (2014) (58)
Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. (2000) (57)
Gradient of RGD-dependent entry of adenoviral vector in nasal and intrapulmonary epithelia: implications for gene therapy of cystic fibrosis. (1996) (57)
Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome. (1983) (57)
Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses. (1998) (56)
Membrane domains of intestinal epithelial cells: distribution of Na+,K+- ATPase and the membrane skeleton in adult rat intestine during fetal development and after epithelial isolation (1989) (56)
Adenovirus-mediated gene transfer to liver. (1995) (56)
Correction of CD18-deficient lymphocytes by retrovirus-mediated gene transfer. (1990) (55)
New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1 (2010) (54)
Human hypoxanthine-guanine phosphoribosyltransferase. Complete amino acid sequence of the erythrocyte enzyme. (1982) (54)
Purinogenic immunodeficiency diseases. Differential effects of deoxyadenosine and deoxyguanosine on DNA synthesis in human T lymphoblasts. (1979) (53)
Identification of an endosomal antigen specific to absorptive cells of suckling rat ileum (1987) (52)
Complete correction of hyperbilirubinemia in the Gunn rat model of Crigler-Najjar syndrome type I following transient in vivo adenovirus-mediated expression of human bilirubin UDP-glucuronosyltransferase. (1996) (50)
Effects of DNA adduct structure and distribution on the mutagenicity and genotoxicity of two platinum anticancer drugs. (1994) (47)
Human hypoxanthine-guanine phosphoribosyltransferase. Purification and characterization of mutant forms of the enzyme. (1981) (47)
Efficient induction of protective anti-malaria immunity by recombinant adenovirus. (1998) (45)
Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD). (1999) (45)
A cell line for high-yield production of E1-deleted adenovirus vectors without the emergence of replication-competent virus. (2000) (44)
Human hypoxanthine-guanine phosphoribosyltransferase. (1983) (43)
Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a nondepleting CD4 antibody. (1999) (42)
Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo. (2001) (42)
Antihyperglycemic action of guanidinoalkanoic acids: 3-guanidinopropionic acid ameliorates hyperglycemia in diabetic KKAy and C57BL6Job/ob mice and increases glucose disappearance in rhesus monkeys. (1993) (42)
Biogenesis of the apical endosome-lysosome complex during differentiation of absorptive epithelial cells in rat ileum. (1991) (42)
Biochemical and functional analysis of an adenovirus-based ligand complex for gene transfer. (1994) (41)
Induction of CD8+ T cells to an HIV-1 antigen upon oral immunization of mice with a simian E1-deleted adenoviral vector. (2004) (41)
Transient depletion of CD4 lymphocyte improves efficacy of repeated administration of recombinant adenovirus in the ornithine transcarbamylase deficient sparse fur mouse (2000) (40)
The formation and toxicity of catechol metabolites of acetaminophen in mice. (1984) (38)
Polarity of endogenous and exogenous glycosyl-phosphatidylinositol-anchored membrane proteins in Madin-Darby canine kidney cells. (1990) (38)
Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates. (1996) (37)
Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill. (1994) (37)
Low-level lead exposure alters morphine antinociception in neonatal rats. (1984) (37)
Pyridine nucleotides and phosphorylation potential of rabbit corneal epithelium and endothelium. (1989) (36)
ICAM-1 expression on bronchial epithelium after recombinant adenovirus infection. (1995) (36)
Fas-Fas ligand interactions play a major role in effector functions of cytotoxic T lymphocytes after adenovirus vector-mediated gene transfer. (1999) (36)
Interactions of cis-diamminedichloroplatinum(II) with 1-beta-D-arabinofuranosylcytosine in LoVo colon carcinoma cells. (1987) (34)
In vivo selection of hepatocytes transduced with adeno-associated viral vectors. (2000) (33)
Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy. (1999) (32)
Production of recombinant adeno-associated virus. (2000) (32)
Human hypoxanthine-guanine phosphoribosyltransferase. Structural alteration in a dysfunctional enzyme variant (HPRTMunich) isolated from a patient with gout. (1984) (32)
The effect of promoter strength in adenoviral vectors containing herpes simplex virus thymidine kinase on cancer gene therapy in vitro and in vivo. (1997) (31)
Treatment of advanced mesothelioma with the recombinant adenovirus H5.010RSVTK: a phase 1 trial (BB-IND 6274). (1996) (31)
Developing adenoviral-mediated in vivo gene therapy for ornithine transcarbamylase deficiency (1998) (29)
BAPS Prize--1997. Fetal gene therapy: efficacy, toxicity, and immunologic effects of early gestation recombinant adenovirus. British Association of Paediatric Surgeons. (1999) (29)
Neonatal cotton rats do not exhibit destructive immune responses to adenoviral vectors. (1996) (29)
Pulmonary delivery of adenovirus vector formulated with dexamethasone–spermine facilitates homologous vector re-administration (2007) (28)
Pharmacologically regulated gene expression in the retina following transduction with viral vectors (2001) (28)
Defective transport and other phenotypes of a periplasmic "leaky" mutant of Escherichia coli K-12 (1979) (27)
Critical differences in the serial measurement of three biochemical markers of bone turnover in the sera of pre- and postmenopausal women. (2001) (27)
Mupirocin resistance in staphylococci: development and transfer of isoleucyl‐tRNA synthetase‐mediated resistance in vitro (1999) (27)
Co-expression of human Kir3 subunits can yield channels with different functional properties. (1999) (27)
The polyamine synthesis inhibitor alpha-difluoromethylornithine is neuroprotective against N-methyl-D-aspartate-induced brain damage in vivo. (1991) (27)
Influence of dietary sodium on renin activity and arterial pressure during anesthesia. (1976) (27)
Adenovirus-mediated gene transfer by perivitelline microinjection of mouse, rat, and cow embryos. (1997) (25)
Radiometric oil well assay for glucokinase in microscopic structures. (1985) (24)
Minimal medium recovery of thermally injured Salmonella senftenberg 4969. (1976) (24)
Retroviruses: delivery vehicle to the liver. (1993) (24)
Hepatocyte transplantation: development of new systems for liver repopulation and gene therapy. (1992) (24)
Hypoxanthine-guanine phosphoribosyltransferase. Genetic evidence for identical mutations in two partially deficient subjects. (1988) (23)
Human adenine phosphoribosyltransferase. Immunochemical quantitation and protein blot analysis of mutant forms of the enzyme. (1982) (23)
Adenovirus-mediated gene transfer to human bronchial submucosal glands using xenografts. (1995) (22)
Human hypoxanthine-guanine phosphoribosyltransferase. Detection of a mutant allele by restriction endonuclease analysis. (1983) (22)
Muscle‐directed gene therapy for hemophilia B with more efficient and less immunogenic AAV vectors (2011) (22)
Ex vivo gene therapy of familial hypercholesterolemia. (1992) (22)
Human hypoxanthine-guanine phosphoribosyltransferase. Tryptic peptides and post-translational modification of the erythrocyte enzyme. (1982) (21)
Expression of retroviral transduced human CD18 in murine cells: an in vitro model of gene therapy for leukocyte adhesion deficiency. (1991) (21)
Animal models of human disease for gene therapy. (1996) (21)
Human adenine phosphoribosyltransferase. Complete amino acid sequence of the erythrocyte enzyme. (1986) (21)
bcl-2 gene therapy exacerbates excitotoxicity. (1999) (21)
Selective repopulation of normal mouse liver by hepatocytes transduced in vivo with recombinant adeno-associated virus. (2001) (21)
MK2206 inhibits hepatocellular carcinoma cellular proliferation via induction of apoptosis and cell cycle arrest. (2014) (20)
Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases. (2001) (19)
Role of CFTR in lysosome acidification. (1992) (19)
Simultaneous measurement of secondary and tertiary tricyclic antidepressants by GC/MS chemical ionization mass fragmentography. (1977) (19)
Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma. (2001) (19)
Plasma disappearance of rabbit α2 HS-glycoprotein and its uptake by bone tissue (1978) (19)
SB 205952, a novel semisynthetic monic acid analog with at least two modes of action (1995) (19)
Prospects for gene therapy of familial hypercholesterolemia. (1990) (18)
In vivo measurement of ureagenesis with stable isotopes (1998) (18)
Membrane domains and macromolecular transport in intestinal epithelial cells. (1988) (17)
Progress and prospects: gene therapy clinical trials (part 1) (2007) (17)
An in vivo animal model of gene therapy for leukocyte adhesion deficiency. (1991) (17)
Gene transfer in human skin with different pseudotyped HIV-based vectors (2007) (16)
Retroviral-mediated gene transfer in human hepatocytes. (1992) (16)
Relationships between energy level and insulin secretion in isolated rat islets of Langerhans. Manipulation of [ATP]/[ADP][Pi] by 2-deoxy-D-glucose. (1992) (16)
The effect of perinatal lead administration on the ontogeny of striatal enkephalin levels in the rat. (1984) (16)
Adenovirus-mediated gene transfer to human fetal lung ex vivo. (1995) (15)
Fast atom bombardment-mass spectrometry for bacterial chemotaxonomy: influence of culture age, growth temperature, gaseous environment and extraction technique. (1992) (15)
Presence of insulin-like growth factors and their binding proteins in rat milk. (1991) (13)
Differences in the human and mouse amino-terminal leader peptides of ornithine transcarbamylase affect mitochondrial import and efficacy of adenoviral vectors. (2001) (13)
Cytoplasmic Signals Mediate Apical Early Endosomal Targeting of Endotubin in MDCK Cells (2001) (12)
Construction of adenoviral vectors. (2000) (12)
Retrovirus-mediated expression of HUG Br1 in Crigler-Najjar syndrome type I human fibroblasts and correction of the genetic defect in Gunn rat hepatocytes. (1995) (12)
Long-term correction of genetic defect of liver function in rat by transplantation of liver cells after ultraviolet irradiation. (1989) (12)
Vectors--shuttle vehicles for gene therapy. (1997) (12)
Ultrastructural localization of variant forms of cystic fibrosis transmembrane conductance regulator in human bronchial epithelial of xenografts. (1994) (12)
Plasma disappearance of rabbit alpha2HS-glycoprotein and its uptake by bone tissue. (1978) (11)
Gene therapy for human liver disease. (1995) (11)
Analysis of polar lipids from some representative enterobacteria, Plesiomonas and Acinetobacter by fast atom bombardment-mass spectrometry. (1992) (11)
Structural changes induced by mupirocin in Staphylococcus aureus cells. (1999) (11)
Blastocyst euploidy and implantation rates in a young (<35 years) and old (≥35 years) presumed fertile and infertile patient population. (2014) (11)
Frontiers in gene therapy: LDL receptor replacement for hypercholesterolemia. (1992) (11)
The small molecular weight, γ-carboxyglutamic acid-containing protein of rabbit bone tissue (1984) (9)
Human gene marker/therapy clinical protocols. (1997) (9)
A Methods Comparison: Clonazepam by Gas Chromatography‐Electron Capture and Gas Chromatography‐Mass Spectroscopy (1979) (9)
Therapeutic strategies for familial hypercholesterolemia based on somatic gene transfer. (1993) (9)
A recombinant adenoviral vector expressing a soluble form of VCAM-1 inhibits VCAM-1/VLA-4 adhesion in transduced synoviocytes. (1995) (9)
Adenoviral vector-mediated gene therapy in the mouse lung: no role of Fas-Fas ligand interactions for elimination of transgene expression in bronchioepithelial cells. (1999) (8)
Recombinant retroviruses containing novel reporter genes. (1993) (8)
Epidermal growth factor and transforming growth factor-alpha mRNA in rat small intestine: in situ hybridization study. (1994) (8)
Gene therapy of hypercholesterolemic disorders. (1995) (8)
The interaction of a component of bone organic matrix with the mineral phase (1976) (8)
Gene therapy: socioeconomic and ethical issues. A roundtable discussion. (1996) (7)
Delivery and evaluation of recombinant adeno‐associated viral vectors in the equine distal extremity for the treatment of laminitis (2017) (7)
Somatic gene transfer in the development of an animal model for primary hyperparathyroidism. (1992) (7)
Polar lipids of strains of Prevotella, Bacteroides and Capnocytophaga analysed by fast atom bombardment mass spectrometry. (1993) (7)
Influence of Chronic Cocaine on Monoamine Neurotransmitters in Human Brain and Animal Model: Preliminary Observations (1992) (7)
A comparison of minerals modified glutamate medium with other media for the enumeration of coliforms in delicatessen foods. (1981) (6)
Making space for intestinal gene therapy. (1997) (6)
A quantitative nonimmunogenic transgene product for evaluating vectors in nonhuman primates. (2000) (6)
Maintenance-dose prediction based on a single determination of concentration: dose of parent drug required to give a desired steady-state concentration of metabolite. (1983) (6)
MHC-independent presentation of mycobacteria to human gamma delta T cells. (1993) (6)
Gas chromatography/mass spectrometry of bacterial amines. (1985) (5)
New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1 (2011) (4)
Biosynthesis of endotubin: an apical early endosomal glycoprotein from developing rat intestinal epithelial cells. (1998) (4)
Identification of the immunodominant cytotoxic T-cell epitope of human -1 antitrypsin (2009) (3)
Complementation of genetic and functional defects in CD18-deficient lymphocytes by retrovirus-mediated gene transfer. (1990) (3)
When bad gene transfer is good. (1996) (3)
T helper cell-independent antibody responses to the transgene product of an e1-deleted adenoviral vaccine require NK1.1 T cells. (2003) (2)
Molecular genetics of hypoxanthine-guanine phosphoribosyltransferase deficiency in man. (1985) (2)
Human hypoxanthine-guanine phosphoribosyltransferase: studies of the normal and five mutant forms of the enzyme. (1983) (2)
Genetic mechanism(s) responsible for a deficiency of adenine phosphoribosyltransferase in man. (1984) (2)
Molecular mechanism(s) of deoxyribonucleoside toxicity in T-lymphoblasts. (1979) (1)
Potential risk of inadvertent germ-line gene transmission statement from the American Society of Gene Therapy to the NIH Recombinant DNA Advisory Committee, March 12, 1999. (1999) (1)
Hypoxanthine-guanine phosphoribosyltransferase in human lymphoblastoid cells: confirmation of four structural variants and demonstration of a new variant (HPRT Ann Arbor). (1984) (1)
Gene therapy in academic medical centers. (1995) (1)
Molecular genetics of the HPRT-deficiency syndromes. (1984) (1)
Human gene marker/therapy clinical protocols. (2000) (0)
HGPRT-deficiency--the molecular basis of the clinical syndromes. (1986) (0)
ACE-2-like enzymatic activity is associated with immunoglobulin in COVID-19 patients (2022) (0)
Analysis of Dezocine in Serum and Urine by High Performance Liquid Chromatography and Pre-Column Derivatizationxs (1994) (0)
Th17 (PP-014) (2010) (0)
Cells-Diamminedichloroplatinum ( II ) in BE Human Colon Carcinoma cis Characterization of Acquired Resistance to Updated (2006) (0)
tRNAgenestranscribed fromtheplastid-like DNAof Plasmodium falciparum (1995) (0)
The primary structure and posttranslational modification of human hypoxanthine-guanine phosphoribosyltransferase. (1984) (0)
The small molecular weight, gamma-carboxyglutamic acid-containing protein of rabbit bone tissue. (1984) (0)
Long-term in vivo cell surface expression of human CD18 in murine hematopoietic cells. (1991) (0)
Human gene marker/therapy clinical protocols. (1996) (0)
RETROVIRAL TRANSDUCED HUMAN CD 18 IN MURINE CELLS 223 (0)
Sequenceandorganization oflarge subunit rRNAgenes fromtheextrachromosomal 35kbcircular DNAofthe malaria parasite Plasmodium falciparum (1993) (0)
Human gene marker/therapy clinical protocols. (1999) (0)

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