Jorge Moscat
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Computer Science
Jorge Moscat's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Jorge Moscat's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- p62 at the Crossroads of Autophagy, Apoptosis, and Cancer (2009) (983)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria (2016) (752)
- The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. (2008) (536)
- Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. (1994) (468)
- The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway (2000) (458)
- p62 is a key regulator of nutrient sensing in the mTORC1 pathway. (2011) (441)
- Protein Kinase C-ζ as a Downstream Effector of Phosphatidylinositol 3-Kinase during Insulin Stimulation in Rat Adipocytes (1997) (408)
- The interaction of p62 with RIP links the atypical PKCs to NF‐κB activation (1999) (400)
- The Product of par-4, a Gene Induced during Apoptosis, Interacts Selectively with the Atypical Isoforms of Protein Kinase C (1996) (381)
- Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway (2001) (376)
- Activation of IκB Kinase β by Protein Kinase C Isoforms (1999) (367)
- The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation (2000) (364)
- Protein kinase C ζ isoform is critical for mitogenic signal transduction (1993) (339)
- Signal integration and diversification through the p62 scaffold protein. (2007) (338)
- p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells. (2016) (333)
- Essential role of RelA Ser311 phosphorylation by ζPKC in NF‐κB transcriptional activation (2003) (321)
- Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase (1997) (311)
- The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. (2004) (308)
- Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62. (2006) (293)
- p62 in Cancer: Signaling Adaptor Beyond Autophagy (2016) (287)
- Activation of Protein Kinase C (α, β, and ζ) by Insulin in 3T3/L1 Cells (1997) (280)
- Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta. (1995) (278)
- The Activation of p38 and Apoptosis by the Inhibition of Erk Is Antagonized by the Phosphoinositide 3-Kinase/Akt Pathway* (1998) (267)
- Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis. (2014) (259)
- Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene (1987) (249)
- DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila (2004) (247)
- Localization of Atypical Protein Kinase C Isoforms into Lysosome-Targeted Endosomes through Interaction with p62 (1998) (237)
- Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta. (1994) (234)
- The atypical protein kinase Cs (2000) (228)
- p62: a versatile multitasker takes on cancer. (2012) (224)
- Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration (2008) (223)
- zeta PKC induces phosphorylation and inactivation of I kappa B‐alpha in vitro. (1994) (223)
- The p62 Scaffold Regulates Nerve Growth Factor-induced NF-κB Activation by Influencing TRAF6 Polyubiquitination* (2005) (223)
- K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells. (2013) (214)
- Insulin Activates Protein Kinases C-ζ and C-λ by an Autophosphorylation-dependent Mechanism and Stimulates Their Translocation to GLUT4 Vesicles and Other Membrane Fractions in Rat Adipocytes* (1999) (200)
- Cell signaling and function organized by PB1 domain interactions. (2006) (191)
- Essential Role of Sequestosome 1/p62 in Regulating Accumulation of Lys63-ubiquitinated Proteins* (2008) (190)
- Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway. (2001) (188)
- The Atypical Protein Kinase C-interacting Protein p62 Is a Scaffold for NF-κB Activation by Nerve Growth Factor* (2001) (188)
- The Bile Acid Taurochenodeoxycholate Activates a Phosphatidylinositol 3-Kinase-dependent Survival Signaling Cascade* (2000) (186)
- Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy. (2017) (184)
- Metabolism shapes the tumor microenvironment. (2017) (177)
- Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes. (1992) (176)
- Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation. (2003) (170)
- Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade (1997) (166)
- Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis (2013) (163)
- Evidence for Involvement of Protein Kinase C (PKC)-ζ and Noninvolvement of Diacylglycerol-Sensitive PKCs in Insulin-Stimulated Glucose Transport in L6 Myotubes. (1997) (159)
- Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. (2005) (158)
- p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer. (2016) (157)
- Phospholipase C-mediated hydrolysis of phosphatidlycholine is an important step in PDGF-stimulated DNA synthesis (1990) (143)
- Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction (1993) (139)
- Role of ζPKC in B‐cell signaling and function (2002) (132)
- Fructose stimulated de novo lipogenesis is promoted by inflammation (2020) (128)
- Feedback on Fat: p62-mTORC1-Autophagy Connections (2011) (128)
- The downregulation of the pro‐apoptotic protein Par‐4 is critical for Ras‐induced survival and tumor progression (1999) (124)
- Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo (1996) (122)
- Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes (1993) (122)
- Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-zeta and (1999) (121)
- p62 links β-adrenergic input to mitochondrial function and thermogenesis. (2013) (115)
- NF‐κB activation by protein kinase C isoforms and B‐cell function (2003) (111)
- TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. (2016) (111)
- PKCζ at the crossroad of NF-κB and Jak1/Stat6 signaling pathways (2006) (109)
- The atypical PKCs in inflammation: NF‐κB and beyond (2012) (107)
- Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. (2013) (107)
- Tumour‐suppression activity of the proapoptotic regulator Par4 (2005) (105)
- Protein kinase C zeta isoform is critical for mitogenic signal transduction. (1993) (103)
- Activation of IkappaB kinase beta by protein kinase C isoforms. (1999) (103)
- Phosphatidylcholine hydrolysis activates NF-kappa B and increases human immunodeficiency virus replication in human monocytes and T lymphocytes (1993) (103)
- Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes. (1999) (103)
- Inactivation of the Inhibitory κB Protein Kinase/Nuclear Factor κB Pathway by Par-4 Expression Potentiates Tumor Necrosis Factor α-induced Apoptosis* (1999) (103)
- Control of T helper 2 cell function and allergic airway inflammation by PKCzeta. (2005) (102)
- The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling (2004) (100)
- Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer. (2019) (98)
- SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity (2013) (97)
- Inactivation of the candidate tumor suppressor par-4 in endometrial cancer. (2007) (95)
- Evidence for a role of phosphatidylcholine‐hydrolysing phospholipase C in the regulation of protein kinase C by ras and src oncogenes. (1990) (94)
- TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. (2016) (93)
- Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade. (2015) (91)
- Identification of Heterogeneous Ribonucleoprotein A1 as a Novel Substrate for Protein Kinase C ζ (*) (1995) (90)
- Cleavage of ζPKC but Not λ/ιPKC by Caspase-3 during UV-induced Apoptosis* (1999) (90)
- A functional role for the p62–ERK1 axis in the control of energy homeostasis and adipogenesis (2010) (89)
- Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ɛ) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-ζ and C-λ (1999) (89)
- Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport. (1997) (88)
- Rapid stimulation of diacylglycerol production in Xenopus oocytes by microinjection of H-ras p21 (1987) (88)
- Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. (2017) (88)
- Par‐4 inhibits Akt and suppresses Ras‐induced lung tumorigenesis (2008) (86)
- Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex (2009) (84)
- Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. (1997) (84)
- Protein Kinase Cζ Represses the Interleukin-6 Promoter and Impairs Tumorigenesis In Vivo (2008) (80)
- The Drosophila Atypical Protein Kinase C-Ref(2)P Complex Constitutes a Conserved Module for Signaling in the Toll Pathway (2002) (78)
- Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes (1996) (78)
- Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor. (2018) (76)
- ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. (2017) (75)
- Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation (2010) (75)
- Evidence for a Bifurcation of the Mitogenic Signaling Pathway Activated by Ras and Phosphatidylcholine-hydrolyzing Phospholipase C (*) (1995) (75)
- MEK5, a New Target of the Atypical Protein Kinase C Isoforms in Mitogenic Signaling (2001) (74)
- Role of zeta PKC in B-cell signaling and function. (2002) (73)
- A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity. (2013) (72)
- Cross-talk between Different Enhancer Elements during Mitogenic Induction of the Human Stromelysin-1 Gene* (1996) (71)
- OPR, PC and AID: all in the PB1 family. (2002) (67)
- Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ. (2015) (66)
- Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1) (2009) (66)
- Genetic inactivation of Par4 results in hyperactivation of NF‐κB and impairment of JNK and p38 (2003) (65)
- Protein Kinase Cζ Mediates Cigarette Smoke/Aldehyde- and Lipopolysaccharide-induced Lung Inflammation and Histone Modifications* (2009) (64)
- PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways. (2006) (63)
- Nephrin deficiency activates NF-kappaB and promotes glomerular injury. (2009) (63)
- NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype (1994) (62)
- Crosstalk between PKCζ and the IL4/Stat6 pathway during T‐cell‐mediated hepatitis (2004) (60)
- Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction (1992) (60)
- ZZ-dependent regulation of p62/SQSTM1 in autophagy (2018) (59)
- Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis. (2021) (57)
- p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. (2014) (55)
- The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation (2006) (54)
- The complexity of the serine glycine one-carbon pathway in cancer (2019) (53)
- PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression. (2020) (53)
- NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegaly. (2020) (53)
- Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21. (1991) (53)
- Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade. (1990) (52)
- Regulation of mature T lymphocyte proliferation and differentiation by Par‐4 (2003) (52)
- c-Myc phosphorylation by PKCζ represses prostate tumorigenesis (2013) (50)
- Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι. (2016) (48)
- Atypical protein kinase C (aPKCζ and aPKCλ) is dispensable for mammalian hematopoietic stem cell activity and blood formation (2011) (48)
- NF-kappaB activation by protein kinase C isoforms and B-cell function. (2003) (47)
- Alterations in levels of different protein kinase C isotypes and their influence on behavior of squamous cell carcinoma of the oral cavity: εPKC, a novel prognostic factor for relapse and survival (1995) (47)
- Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-κB activation and invasive prostate carcinoma (2009) (47)
- The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer (2018) (47)
- The Dual Roles of the Atypical Protein Kinase Cs in Cancer. (2019) (46)
- miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3. (2016) (44)
- The calcium signal for Balb/MK keratinocyte terminal differentiation induces sustained alterations in phosphoinositide metabolism without detectable protein kinase C activation. (1989) (44)
- Rapid stimulation of diacylglycerol production in Xenopus oocytes by microinjection of H-ras p21. (1988) (43)
- p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors. (2019) (43)
- Zeta PKC plays a critical role during stromelysin promoter activation by platelet-derived growth factor through a novel palindromic element. (1994) (42)
- Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine‐hydrolysing phospholipase C. (1991) (42)
- Loss of PKCλ/ι impairs Th2 establishment and allergic airway inflammation in vivo (2009) (41)
- Phospholipase C-mediated hydrolysis of phosphatidylcholine is activated by muscarinic agonists. (1989) (40)
- p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis. (2017) (39)
- Protein Kinase C-zMediates NF-kB Activation in Human Immunodeficiency Virus-Infected Monocytes (1996) (38)
- Protein kinase C-independent expression of stromelysin by platelet-derived growth factor, ras oncogene, and phosphatidylcholine-hydrolyzing phospholipase C. (1991) (37)
- Molecular characterization of a novel transcription factor that controls stromelysin expression (1995) (37)
- Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. (1991) (35)
- A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity. (2014) (35)
- Protein kinase C zeta (2005) (34)
- TRAF6 and p62 inhibit amyloid β-induced neuronal death through p75 neurotrophin receptor (2012) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- PKCzeta-regulated inflammation in the nonhematopoietic compartment is critical for obesity-induced glucose intolerance. (2010) (33)
- Epidermal growth factor activates phosphoinositide turnover and protein kinase C in BALB/MK keratinocytes. (1988) (32)
- Phospholipase C-mediated hydrolysis of phosphatidylcholine is a target of transforming growth factor beta 1 inhibitory signals (1992) (32)
- To aggregate or not to aggregate? A new role for p62 (2009) (31)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo (2010) (31)
- Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance (2018) (31)
- The fluidity of liver plasma membranes from patients with different types of liver injury (1986) (30)
- Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population. (2020) (30)
- Protein Kinase C (PKC)ζ-mediated Gαq Stimulation of ERK5 Protein Pathway in Cardiomyocytes and Cardiac Fibroblasts* (2012) (30)
- Gαq Acts as an Adaptor Protein in Protein Kinase Cζ (PKCζ)-mediated ERK5 Activation by G Protein-coupled Receptors (GPCR)*♦ (2010) (29)
- Metabolic reprogramming of the tumor microenvironment by p62 and its partners. (2018) (26)
- Phospholipase C-diglyceride lipase is a major pathway for arachidonic acid release in macrophages. (1986) (25)
- Serrated Colorectal Cancer: The Road Less Travelled? (2019) (24)
- Ouabain inhibits p38 activation in thymocytes (2008) (23)
- Interaction of SQSTM1 with the motor protein dynein – SQSTM1 is required for normal dynein function and trafficking (2014) (23)
- Polarized Subcellular Localization of JAK/STAT Components Is Required for Efficient Signaling (2008) (22)
- Endothelial cell growth factor and ionophore A23187 stimulation of production of inositol phosphates in porcine aorta endothelial cells. (1988) (19)
- The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation (2020) (19)
- Activation of phosphatidylcholine-specific phospholipase C in cell growth and oncogene transformation. (1989) (19)
- The p 62 Scaffold Regulates Nerve Growth Factor-induced NF-B Activation by Influencing TRAF 6 Polyubiquitination * (2005) (18)
- The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors (2019) (18)
- Deconstructing tumor heterogeneity: the stromal perspective (2020) (18)
- Supplemental Data The Signaling Adaptor p 62 Is an Important NF-κ B Mediator in Tumorigenesis (2008) (16)
- Functional properties of isolated hepatocytes from ethanol‐treated rat liver (1985) (16)
- Mitogenic activity and inositide metabolism in thrombin-stimulated pig aorta endothelial cells. (1987) (16)
- The atypical PKC scaffold protein P62 is a novel target for anti-inflammatory and anti-cancer therapies. (2002) (16)
- Membrane fluidity and thromboxane synthesis in platelets from patients with severe atherosclerosis. (1986) (15)
- Yap1-Scribble polarization is required for hematopoietic stem cell division and fate. (2020) (15)
- Regulation and role of the atypical PKC isoforms in cell survival during tumor transformation. (2001) (15)
- Akt regulation and lung cancer: A novel role and mechanism of action for the tumor suppressor Par-4 (2008) (14)
- Zymosan-induced release of inositol phosphates at resting cytosolic Ca2+ concentrations in macrophages. (1987) (11)
- NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ (2021) (11)
- Par-4 Keeps the Atypical PKCs at Bay (2003) (11)
- The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62 (2022) (11)
- Ca2+-induced changes in the secondary structure of a 60 kDa phosphoinositide-specific phospholipase C from bovine brain cytosol. (1988) (11)
- Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages. (1986) (10)
- Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum (2021) (10)
- The macroenviromental control of cancer metabolism by p62 (2018) (9)
- Th1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators (2012) (9)
- The interaction of p 62 with RIP links the atypical PKCs to NF-κ B activation (2013) (9)
- The fluidity of plasma membranes from ethanol-treated rat liver (1984) (8)
- PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis. (2021) (8)
- Role of adipose and hepatic atypical protein kinase C lambda (PKCλ) in the development of obesity and glucose intolerance (2012) (7)
- Arachidonic acid releasing systems in pig aorta endothelial cells. (1986) (7)
- ArticleThe Atypical PKC-Interacting Protein p 62 Is an Important Mediator of RANK-Activated Osteoclastogenesis (2004) (7)
- Fine tuning NF-κB: new openings for PKC-ζ (2010) (7)
- Nuclear fallout provides a new link between aPKC and polarized cell trafficking (2016) (6)
- Nutrient stress revamps cancer cell metabolism (2015) (6)
- Nephrin Deficiency Activates NF- B and Promotes Glomerular Injury (2009) (5)
- A new family with hereditary choreo-acanthocytosis. (1987) (5)
- Effect of ethanol on the arachidonic acid metabolism in mouse peritoneal macrophages. (1987) (5)
- S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia (2022) (4)
- The interplay between PRKCI/PKCλ/ι, SQSTM1/p62, and autophagy orchestrates the oxidative metabolic response that drives liver cancer (2020) (3)
- A Dominant Negative Protein Kinase C 4 Subspecies Blocks NF-vdB Activation (2003) (3)
- An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis (2020) (3)
- The ins and outs of protein phosphorylation (2000) (2)
- PKCzeta-mediated GalphaQ stimulation of the ERK5 pathway plays a key role in cardiac hypertrophy (2007) (2)
- Immunosurveillance, interferon, and autophagic networking in cancer: the PRKCI-ULK2 paradigm (2021) (2)
- The p62 Scaffold Regulates NGF-Induced NF- κ B Activation by Influencing TRAF6 Polyubiquitination (2005) (2)
- Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer. (2022) (2)
- Protein kinase Cλ/ι in cancer: a contextual balance of time and signals. (2022) (2)
- Hydrolysis Activates NF-KBandIncreases HumanImmunodeficiency VirusReplication inHuman Monocytes andT Lymphocytes (1993) (1)
- AUTHOR'S CORRECTION Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation (2011) (1)
- PKC ζ-MEDIATED G α Q STIMULATION OF THE ERK 5 PATHWAY IN CARDIOMYOCYTES AND CARDIAC FIBROBLASTS (2011) (1)
- NF-κB restricts NLRP3 inflammasome activation via p62-dependent mitophagy which eliminates mitochondrial signals (2016) (1)
- The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors (2019) (1)
- Phospholipid Degradation and ζPKC Activation during Mitogenic Signal Transduction (1994) (0)
- Protein Kinase C (cid:2) Represses the Interleukin-6 Promoter and Impairs Tumorigenesis In Vivo (cid:1) † (2008) (0)
- P1-040 Accumulation of tau and amyloid beta in p62 deficient mice (2006) (0)
- Polarized Subcellular Localization Required for Efficient Signaling (0)
- review NF-κB activation by protein kinase C isoforms and B-cell function (2003) (0)
- Contents, Vol. 77, 1987 (1987) (0)
- Role of the PKCλ/ι in Th2 establishment and airway hyperresponsiveness (90.11) (2009) (0)
- Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation (2011) (0)
- Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis (2020) (0)
- Targeting the Adipocyte-Tumor Cell Interaction in Prostate Cancer Treatment (2015) (0)
- Abstract 978: microRNA-211 modulates energy metabolism in human melanoma cells by destabilizing HIF1-α and downregulating PDK4 (2014) (0)
- Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α (2018) (0)
- AWARD NUMBER: W81XWH-13-1-0354 TITLE: “Targeting the Adipocyte-Tumor Cell Interaction in Prostate Cancer Treatment” PRINCIPAL INVESTIGATOR: (2016) (0)
- Interaction of PB1 domain-containing signaling molecules in the regulation of Th2 response (174.16) (2012) (0)
- Protein Kinase C 6 Isoform Is Critical for &-dependent Promoter Activation by (1994) (0)
- Short communication Ouabain inhibits p38 activation in thymocytes (2008) (0)
- NBR1 in the regulation of T cell development and differentiation (P1000) (2013) (0)
- Advisory Board and Contents (2021) (0)
- P4-313 Presenilin-1 induces NF-κB activation via a RIP-P62-APKC signaling cascade (2004) (0)
- Meeting on Signalling Networks in Immunity and Inflammation (2006) (0)
- Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation (2011) (0)
- Editorial Board (2009) (0)
- Effect of ethanol on arachidonic acid metabolism in macrophages. (1991) (0)
- Abstract SY01-02: Autophagy and metabolic reprogramming in the tumor stroma (2015) (0)
- Atypical protein kinase C (aPKC) isoforms {zeta} and {lambda}/{iota} synergically control Th2 development and function (2010) (0)
- Nuclear fallout provides a new link between aPKC and polarized cell trafficking (2016) (0)
- 617 – Simultaneous Loss of Both Atypical Protein Kinase C Drives Serrated Intestinal Cancer with Mesenchymal Activation and Immunosuppression (2019) (0)
- Atypical Protein Kinase C λ/I Oncogenic Signaling through the Chromatin Modifier Satb2 Is Required for Leukemic B-Cell Progenitor Differentiation Arrest and Leukemogenesis (2016) (0)
- Whole-mount staining of mouse colorectal cancer organoids and fibroblast-organoid co-cultures. (2023) (0)
- ZZ-dependent regulation of p62/SQSTM1 in autophagy (2018) (0)
- Abstract SY22-02: Tumor suppression by p62 through the metabolic reprogramming of the stroma (2017) (0)
- Sqstm1 Is Required to Retain Hematopoietic Stem Cell/ Progenitors As a Negative Regulator of Macrophage-Dependent Inflammatory Signaling in the Bone Marrow Osteoblastic Niche (2014) (0)
- Fructose stimulated de novo lipogenesis is promoted by inflammation (2020) (0)
- Edinburgh Research Explorer The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation (2017) (0)
- Atypical protein kinase c isoform ख (PKC-Z), but not akt kinase mediates taurochenodeoxycholate-activated survival signals (2000) (0)
- Effects of Escherichia coli lipopolysaccharide on the phosphoinositide metabolism and serotonin secretion in thrombin-activated platelets. (1987) (0)
- Stress-Activated NRF 2-MD M 2 Cascade Controls Neoplastic Progression in Pancreas Graphical (2017) (0)
- Subject Index, Vol. 77, 1987 (1987) (0)
- Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes (1992) (0)
- Correction (2020) (0)
- Air-liquid organotypic assays to investigate cellular crosstalk in the tumor microenvironment of cancer cells (2022) (0)
- Role of the PKC{lambda}/{iota} in Th2 establishment and airway hyperresponsiveness (2009) (0)
- The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation (2020) (0)
- Stromal upregulation of SOX2 promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population (2021) (0)
- Atypical PKCs, NF-κB, and Inflammation (2010) (0)
- Correction for Linares et al., “Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation” (2017) (0)
- Atypical protein kinase C (aPKC) isoforms ζ and λ/ι synergically control Th2 development and function (134.13) (2010) (0)
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What Schools Are Affiliated With Jorge Moscat?
Jorge Moscat is affiliated with the following schools:
