John J. Orloff
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John J. Orloffmedical Degrees
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#2335
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Epidemiology
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John J. Orloffphilosophy Degrees
Philosophy
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Medical Philosophy
John J. Orloff's Degrees
- Doctorate Medicine University of California, San Francisco
- PhD Epidemiology University of California, Berkeley
Why Is John J. Orloff Influential?
(Suggest an Edit or Addition)John J. Orloff's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Zoledronic acid and clinical fractures and mortality after hip fracture. (2007) (1696)
- New and Emerging Etiologies for Community‐Acquired Pneumonia with Implications for Therapy: A Prospective Multicenter Study of 359 Cases (1990) (902)
- Preparation and study of fragments of single rabbit nephrons. (1966) (784)
- Defining the roles of parathyroid hormone-related protein in normal physiology. (1996) (545)
- Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. (1990) (519)
- The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder. (1962) (447)
- Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3',5'-monophosphate, and theophylline. (1968) (426)
- The renal clearance of alkali-stable inulin. (1955) (408)
- Change in Bone Turnover and Hip, Non‐Spine, and Vertebral Fracture in Alendronate‐Treated Women: The Fracture Intervention Trial (2004) (387)
- Therapeutic equivalence of alendronate 70 mg onceweekly and alendronate 10 mg daily in the treatment of osteoporosis (2000) (376)
- Relationship between acidification of the urine and potassium metabolism; effect of carbonic anhydrase inhibition on potassium excretion. (1951) (330)
- The role of adenosine 3',5'-phosphate in the action of antidiuretic hormone. (1967) (328)
- A salt-wasting syndrome associated with cerebral disease. (1950) (323)
- Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group. (2000) (314)
- Effect of Prostaglandin (PGEI) on the Permeability Response of Toad Bladder to Vasopressin, Theophylline and Adenosine 3′,5′-monophosphate (1965) (247)
- Ion transport in cortical collecting tubule; effect of amiloride. (1974) (230)
- Parathyroid hormone-related protein as a prohormone: posttranslational processing and receptor interactions. (1994) (218)
- THE MECHANISM OF ANTIDIURESIS ASSOCIATED WITH THE ADMINISTRATION OF HYDROCHLOROTHIAZIDE TO PATIENTS WITH VASOPRESSIN-RESISTANT DIABETES INSIPIDUS. (1962) (189)
- Control of fluid absorption in the renal proximal tubule. (1968) (189)
- Oxygen consumption and active transport in separated renal tubules. (1962) (184)
- The effect of vasopressin and of theophylline on the concentration of adenosine 3',5'-phosphate in the urinary bladder of the toad. (1965) (177)
- Parathyroid hormone-like proteins: biochemical responses and receptor interactions. (1989) (172)
- Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture. (2007) (161)
- ULTRASTRUCTURAL STUDIES OF VASOPRESSIN EFFECT ON ISOLATED PERFUSED RENAL COLLECTING TUBULES OF THE RABBIT (1968) (159)
- Prognosis of patients hospitalized with community-acquired pneumonia. (1990) (153)
- The future of drug development: advancing clinical trial design (2009) (148)
- The mechanism of the excretion of ammonia in the dog. (1956) (134)
- The effects of infusions of chlorothiazide on urinary dilution and concentration in the dog. (1961) (129)
- PATHS OF TRANSTUBULAR WATER FLOW IN ISOLATED RENAL COLLECTING TUBULES (1969) (115)
- The effects of an increase in plasma volume on the metabolism and excretion of water and electrolytes by normal subjects. (1951) (112)
- Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines. (1995) (108)
- Asymptomatic hyponatremia in pulmonary tuberculosis. (1950) (98)
- Weekly administration of alendronate: rationale and plan for clinical assessment. (2000) (97)
- Stromal cells are critical targets in the regulation of mammary ductal morphogenesis by parathyroid hormone-related protein. (1998) (93)
- Effect of adrenergic agents on toad bladder response to ADH, 3',5'-AMP, and theophylline. (1968) (92)
- Characteristics of NaCl and water transport in the renal proximal tubule. (1971) (91)
- Effect of ADH, aldosterone, ouabain, and amiloride on toad bladder epithelial cells. (1972) (88)
- Abnormalities of water and electrolyte metabolism in rats with hypothalamic lesions. (1950) (86)
- Carbonic anhydrase inhibitors. (1956) (86)
- THE CELLULAR MODE OF ACTION OF ANTIDIURETIC HORMONE. (1964) (85)
- Effects of ADH and other agents on cyclic AMP accumulation in toad bladder epithelium. (1974) (85)
- Effect of adrenal steroid hormones on the response of the toad's urinary bladder to vasopressin. (1969) (84)
- The effect of variations in solute excretion and vasopressin dosage on the excretion of water in the dog. (1958) (82)
- Transient ventricular fibrillation (1949) (80)
- Low Bone Density is Not Associated with Aortic Calcification (2001) (79)
- The Effect of Norepinephrine and Dibutyryl Cyclic Adenosine Monophosphate on Cation Transport in Duck Erythrocytes (1971) (79)
- Parathyroid hormone-related protein modulates the effect of transforming growth factor-beta on deoxyribonucleic acid and collagen synthesis in fetal rat bone cells. (1989) (77)
- An example of cellular hyperosmolarity. (1950) (75)
- Effect of strophanthidin on electrolyte excretion in the chicken. (1958) (74)
- Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives (2010) (74)
- Effect of hypertonicity on permeability properties of the toad bladder. (1970) (74)
- Electrical properties of isolated perfused rabbit renal tubules. (1968) (73)
- The effect of potassium in nephrectomized rats with hypokalemic alkalosis. (1953) (73)
- Regulation of ammonia excretion in the rat. (1955) (72)
- Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. (1992) (72)
- Antidiuretic hormone. (1981) (68)
- Toxic megacolon in cytomegalovirus colitis. (1989) (66)
- Electrical potential difference across proximal convoluted tubules. (1970) (65)
- Effect of strophanthidin on electrolyte content and PAH accumulation of rabbit kidney slices. (1962) (62)
- Analysis of PTHRP binding and signal transduction mechanisms in benign and malignant squamous cells. (1992) (59)
- The effect of the administration of sodium bicarbonate and ammonium chloride on the excretion and production of ammonia; the absence of alterations in the activity of renal ammonia-producing enzymes in the dog. (1959) (59)
- Renal concentrating defect in Sjogren's syndrome. (1962) (56)
- Amino-terminal parathyroid hormone-related protein: specific binding and cytosolic calcium responses in rat insulinoma cells. (1993) (56)
- Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor. (2004) (56)
- Vasopressin-like effects of adenosine 3′,5′,-phosphate (cyclic 3′,5′-AMP) and theophylline in the toad bladder (1961) (55)
- A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol trisphosphate in a squamous carcinoma cell line. (1996) (54)
- Role of cyclic nucleotides in the transport of water and electrolytes. (1977) (54)
- Cardiovascular safety of lumiracoxib: a meta-analysis of all randomized controlled trials > or =1 week and up to 1 year in duration of patients with osteoarthritis and rheumatoid arthritis. (2005) (52)
- Effect of norepinephrine and hypertonicity on K influx and cyclic AMP in duck erythrocytes. (1976) (51)
- Accumulation of carboxy-terminal fragments of parathyroid hormone-related protein in renal failure. (1993) (49)
- Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy. (1989) (48)
- The mechanism of potassium excretion in the chicken. (1959) (47)
- Active chloride transport in the isolated toad bladder. (1967) (47)
- Relation between toad bladder potassium content and permeability response to vasopressin. (1966) (47)
- Significance of carbon dioxide tension in urine. (1952) (45)
- The effects of concentrated salt-poor albumin on the metabolism and excretion of water and electrolytes in nephrosis and toxemia of pregnancy. (1950) (42)
- The effect of aldosterone on the accumulation of adenosine 3':5'-cyclic monophosphate in toad bladder epithelial cells in response to vasopressin and theophylline. (1972) (41)
- ACTIVE CATION TRANSPORT BY KIDNEY TUBULES AT O C. (1964) (41)
- EFFECT OF PROSTAGLANDIN (PGE-1) ON THE PERMEABILITY RESPONSE OF TOAD BLADDER TO VASOPRESSIN, THEOPHYLLINE AND ADENOSINE 3',5'-MONOPHOSPHATE. (1965) (40)
- Ca++ and Mg++ effects on toad bladder response to cyclic AMP, theophylline, and ADH analogues. (1967) (39)
- The effect of aldosterone of glycolysis in the urinary bladder of the toad. (1969) (39)
- Lack of relationship of potential difference to fluid absorption in the proximal renal tubule. (1975) (39)
- Evaluation of housestaff physicians’ preparation and interpretation of sputum gram stains for communityacquired pneumonia (1991) (37)
- Effect of temperature and medium K on Na and K fluxes in separated renal tubules. (1966) (35)
- Factors affecting the transport of potassium and hydrogen ions by the renal tubules. (1954) (35)
- SODIUM AND POTASSIUM FLUX OF SEPARATED RENAL TUBULES. (1964) (35)
- Recommendations for an update of the current (2001) regulatory requirements for registration of drugs to be used in the treatment of osteoporosis in postmenopausal women and in men (2005) (35)
- Mechanism of desensitization of the cloned vasopressin V1a receptor expressed in Xenopus oocytes. (1994) (34)
- ACTIVATION OF PHOSPHORYLASE IN TOAD BLADDER AND MAMMALIAN KIDNEY BY ANTIDIURETIC HORMONE. (1963) (31)
- Therapeutic Equivalence of Alendronate 35 Milligrams Once Weekly and 5 Milligrams Daily in the Prevention of Postmenopausal Osteoporosis (2003) (31)
- p-Aminohippurate uptake and exchange by separated renal tubules. (1969) (30)
- Effect of Prostaglandin E1 on the Permeability Response of the Isolated Collecting Tubule to Vasopressin (1968) (30)
- The effect of aldosterone on cyclic nucleotide phosphodiesterase activity in toad urinary bladder (1973) (29)
- Fluid absorption by proximal tubules in the absence of a colloid osmotic gradient. (1973) (27)
- Effect of inhibitors of sodium transport on response of toad bladder to ADH and cyclic AMP. (1970) (26)
- Effect of metabolic inhibitors on the response of the toad bladder to vasopressin. (1966) (26)
- A pharmacological comparison of parathyroid hormone receptors in human bone and kidney. (1992) (25)
- Expression and role of parathyroid hormone-related protein in human renal proximal tubule cells during recovery from ATP depletion. (1999) (24)
- Recommendations for the registration of agents to be used in the prevention and treatment of glucocorticoid-induced osteoporosis: updated recommendations from the Group for the Respect of Ethics and Excellence in Science. (2005) (22)
- Effect of amphotericin B on permeability and short-circuit current in toad bladder. (1967) (21)
- CYSTEINE EFFECT ON TOAD BLADDER RESPONSE TO VASOPRESSIN, CYCLIC AMP, AND THEOPHYLLINE. (1964) (20)
- PITFALLS IN THE USE OF STOP‐FLOW FOR THE LOCALIZATION OF DIURETIC ACTION, WITH SPECIAL REFERENCE TO Na REABSORPTION (1966) (19)
- Effect of strophanthidin on fluxes of potassium in rabbit kidney slices. (1963) (18)
- Effects of concentrated salt-poor human albumin on metabolism and excretion of water and electrolytes in dogs. (1950) (17)
- Compliance, Persistence, Healthcare Resource Use, and Treatment Costs Associated with Aliskiren plus ARB versus ACE Inhibitor plus ARB Combination Therapy (2011) (17)
- Copayment level, treatment persistence, and healthcare utilization in hypertension patients treated with single-pill combination therapy (2011) (16)
- Chloride flux in rabbit kidney tubules in vitro. (1967) (15)
- Innovative approaches to clinical development and trial design. (2011) (15)
- The carboxy-terminus of parathyroid hormone--inert or invaluable? (1995) (15)
- Interspecies comparison of renal cortical receptors for parathyroid hormone and parathyroid hormone‐related protein (1991) (14)
- FACTORS INVOLVED IN THE ACTION OF CYCLIC AMP, ON THE PERMEABILITY OF MAMMALIAN KIDNEY AND TOAD URINARY BLADDER (1971) (14)
- The pathogenesis of hyponatremia in congestive heart failure. (1961) (13)
- The rôle of the kidney in the regulation of acid-balance. (1956) (12)
- Chart review of patients on valsartan-based single-pill combinations vs. ARB-based free combinations for BP goal achievement (2010) (12)
- Effect of parathyroid hormone and cyclic AMP on protein phosphorylation in rabbit kidney cortex. (1976) (11)
- Release of cyclic AMP by toad urinary bladder. (1975) (11)
- Ammonium, urea, and systemic pH regulation. (1987) (10)
- Immunohistochemical detection of parathyroid hormone-related protein in a cutaneous squamous cell carcinoma causing humoral hypercalcemia of malignancy. (1999) (10)
- Effect of aldosterone on the sodium content and energy metabolism of epithelial cells of the toad urinary bladder. (1972) (9)
- Asymptomatic hyponatremia in pulmonary tuberculosis. (1950) (8)
- Refractoriness of toad bladder to stimulation of sodium transport. (1972) (8)
- The transport of priscoline by the renal tubules. (1953) (7)
- Acute cardiac tamponade due to cardiac actinomycosis. (1988) (7)
- The Rôle of the Kidney in the Regulation of Acid-Base Balance (1956) (7)
- Transient ventricular fibrillation; the prefibrillary period during established auriculoventricular dissociation with a note on the phonocardiograms obtained at such times. (1949) (7)
- Innovation in Development, Regulatory Review, and Use of Clinical Advances: A Vital Direction for Health and Health Care (2016) (6)
- Effect of sodium transport and vasopression on the oxidation of palmitic acid by the toad bladder. (1968) (5)
- Role of prostaglandin E (PGE) in the modulation of the action of vasopressin on water flow in the urinary bladder of the toad and mammalian kidney (2005) (5)
- Regulation of Water and Electrolyte Movement by Vasopressin and Cyclic Nucleotides in Kidney (1982) (4)
- Effect of aldosterone on cyclic-AMP metabolism in the urinary bladder of the toad. (1973) (4)
- Communicating With the FDA: The “Third Rail” of a New Model for Drug Development (2008) (4)
- Clonal variation of p53 expression and proliferative phenotype in A253 squamous carcinoma cells. (1996) (4)
- Preparation and study of fragments of single rabbit nephrons. (1997) (4)
- The effect of some nucleotides and related compounds on sodium transport and water permeability of the urinary bladder of the toad. (1973) (3)
- Renal tubular effects of ammonium salts on electrolyte transport. (1961) (3)
- The Relationship Between Potassium Excretion and Urine Acidification (2008) (2)
- INTRODUCTORY REMARKS: SECRETION AND MEMBRANE FUNCTION (1971) (1)
- Opportunities for innovation in the design and execution of clinical trials (2012) (1)
- Defective protein phosphorylation in renal medulla of vasopressin-resistant mice. (1981) (1)
- The effect of concentrated salt-poor human albumin on the excretion of water and electrolytes in normal dogs. (1950) (1)
- PCV15 BLOOD PRESSURE GOAL ACHIEVEMENT AMONG HYPERTENSION PATIENTS TREATED WITH VALSARTAN-BASED SINGLE PILL COMBINATION VS. ARB-BASED FREE COMBINATION IN SOUTH CENTRAL REGION (2010) (1)
- The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder. 1962. (1999) (1)
- Hyponatremia (1959) (0)
- Comments on recent advances in renal physiology. (1960) (0)
- THE RENAL CLEARANCE OF ALKALI-STABLE INULIN By MACKENZIE WALSER (2013) (0)
- AN EXAMPLE OF CELLULAR HYPEROSMOLARITY1 (0)
- Renal physiology from past to present. (1976) (0)
- PCV54 THE INCIDENCE AND COST OF SURGICAL SITE INFECTION (SSI) FOR COMMON CARDIOTHORACIC SURGICAL PROCEDURES IN THE USA: A STUDY USING THE PREMIER PERSPECTIVETM DATABASE (PPD) (2010) (0)
- ASYMPTOMATIC HYPONATREMIA IN PULMONARY TUBERCULOSIS 1 (0)
- PCV51 AN ASSESSMENT OF DIRECT COSTS OF SINGLE PILL VERSUS FREE COMBINATION ARB/CCB THERAPY IN PATIENTS WITH HYPERTENSION (2010) (0)
- AN EXAMPLEOF CELLULAR HYPEROSMOLARITY (0)
- THE MECHANISM OF THE EXCRETION OF AMMONIAIN THE DOG By JACK ORLOFF (2013) (0)
- PCV21 A BENEFIT-RISK ASSESSMENT OF USING CYP2C19 GENOTYPE INFORMATION TO GUIDE ANTIPLATELET THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME (2010) (0)
- Retrouvera-t-on l'antimatiere? (2006) (0)
- PCV52 COMPLIANCE AND HEALTH CARE UTILIZATION AMONG PATIENTS WITH HYPERTENSION TREATED WITH SINGLE PILL VS. FREE COMBINATION ANTIHYPERTENSIVE THERAPY: U.S. NATIONAL AND STATE LEVEL RESULTS FROM A CLAIMS DATABASE ANALYSIS (2010) (0)
- PCV16 AN ASSESSMENT OF OPTIMAL LIPID VALUE ATTAINMENT AND ASSOCIATED DYSLIPIDEMIA TREATMENT PATTERNS FROM 2005 TO 2009 IN A COMMERCIALLY INSURED POPULATION (2010) (0)
- CELLULAR MODE OF ACTION OF ANTIDIURETIC HORMONE. (1965) (0)
- Editorial comments: kidney function and cyclic nucleotides. (1980) (0)
- DISCUSSION (1971) (0)
- Effect of Vasopressin on Na Transport in Isolated Perfused Renal Cortical Collecting Tubules (1972) (0)
- PCV53 ALISKIREN COMBINED WITH ANGIOTENSIN II-RECEPTOR BLOCKERS (ARB) RESULTED IN BETTER OUTCOMES COMPARED TO ARB COMBINED WITH ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACEI): RESULTS FROM A CLAIMS DATABASE ANALYSIS (2010) (0)
- WATER BALANCE AND ACTION OF ANTIDIURETIC HORMONE. (1964) (0)
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