John Power Kane

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John Power Kane is affiliated with the following schools: Queen's University at Kingston, Rockefeller University, University of Washington, University of California, San Francisco

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Doctorate Medicine Harvard University

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John Power Kane's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. (1990) (837)
A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci (2008) (670)
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity (2012) (555)
Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. (1980) (503)
Apolipoprotein L-I is the trypanosome lytic factor of human serum (2003) (496)
Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. (1973) (486)
Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS (1994) (452)
Multi-ethnic genome-wide association study for atrial fibrillation (2018) (425)
Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. (2002) (419)
A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins. (1973) (418)
Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans. (1970) (354)
Apoprotein composition of very low density lipoproteins of human serum. (1975) (352)
Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. (1994) (342)
Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis. (2012) (325)
Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. (2007) (304)
Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia (2004) (285)
Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows. (1981) (282)
Apolipoprotein B: structural and metabolic heterogeneity. (1983) (279)
Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. (1997) (221)
A multilocus genotyping assay for candidate markers of cardiovascular disease risk. (1999) (220)
Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. (1993) (218)
Bladder cancer and squamous metaplasia in spinal cord injury patients. (1977) (216)
Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification. (1982) (216)
Apolipoprotein L, a New Human High Density Lipoprotein Apolipoprotein Expressed by the Pancreas (1997) (212)
Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia. (1977) (209)
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia (2007) (208)
Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity. (1995) (205)
A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency. (2015) (201)
Normalization of low-density-lipoprotein levels in heterozygous familial hypercholesterolemia with a combined drug regimen. (1981) (197)
Cholestasis: Lamellar Structure of the Abnormal Human Serum Lipoprotein (1971) (192)
Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins. (1973) (191)
Factors affecting the integrity of high density lipoproteins in the ultracentrifuge. (1982) (184)
Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. (1985) (179)
Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. (1980) (176)
Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study (2007) (172)
Identification of four gene variants associated with myocardial infarction. (2005) (169)
Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in normal and lipoprotein lipase-deficient humans. (1984) (164)
Binding of High Density Lipoprotein (HDL) and Discoidal Reconstituted HDL to the HDL Receptor Scavenger Receptor Class B Type I* (2000) (157)
A Polymorphism in the Protease-Like Domain of Apolipoprotein(a) Is Associated With Severe Coronary Artery Disease (2007) (156)
Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. (1981) (153)
A risk factor for atherosclerosis: triglyceride-rich lipoproteins. (2001) (145)
Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma. (1983) (139)
Levels and Interrelationships of Serum and Lipoprotein Cholesterol and Triglycerides (1981) (137)
Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids. (2003) (132)
Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. (2001) (132)
Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins. (1992) (130)
Concentration and Composition of Lipoproteins in Blood Plasma of the WHHL Rabbit (1982) (127)
Metabolism of apoprotein B of plasma very low density lipoproteins in the rat. (1975) (125)
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. (2009) (125)
Severe hypertriglyceridemia is primarily polygenic. (2019) (116)
Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. (2015) (115)
The primary stone event: a new hypothesis involving a vascular etiology. (2004) (114)
Apolipoprotein E e4 Allele Increases the Risk of Early Postoperative Delirium in Older Patients Undergoing Noncardiac Surgery (2007) (113)
Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. (1996) (112)
Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia. (1995) (111)
Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients With cholesteryl ester storage disease (2013) (110)
Triglyceride-rich lipoproteins prevent septic death in rats (1995) (110)
Five common gene variants identify elevated genetic risk for coronary heart disease (2007) (102)
HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property (2009) (100)
Human cholesterol 7a-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype (2018) (100)
Regulated expression of apolipoprotein E by human retinal pigment epithelial cells Published, JLR Papers in Press, November 1, 2003. DOI 10.1194/jlr.M300306-JLR200 (2004) (97)
Remnants of Lipoproteins of Intestinal and Hepatic Origin in Familial Dysbetalipoproteinemia (1983) (97)
Gene Variants of VAMP8 and HNRPUL1 Are Associated With Early-Onset Myocardial Infarction (2006) (94)
Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency. (2014) (90)
A single copy of apolipoprotein B-48 is present on the human chylomicron remnant. (1997) (89)
Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction. (1998) (88)
Characteristics of human lipoproteins isolated by selected-affinity immunosorption of apolipoprotein A-I. (1984) (87)
Mechanism of the hypolipemic effect of clofibrate in postabsorptive man. (1973) (87)
Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. (2000) (86)
Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3. (1983) (85)
Mapping and characterization of structural variation in 17,795 human genomes (2020) (84)
Drugs and lipid metabolism. (1973) (84)
Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia. (1987) (84)
Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium (2009) (81)
Chylomicrons enhance endotoxin excretion in bile (1993) (81)
The protective effect of serum lipoproteins against bacterial lipopolysaccharide. (1993) (80)
Pre-beta high density lipoprotein. Unique disposition of apolipoprotein A-I increases susceptibility to proteolysis. (1990) (80)
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish (2015) (80)
Human retinal pigment epithelial cells express scavenger receptors BI and BII. (2002) (78)
Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. (2004) (78)
Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits. (1983) (77)
Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. (2014) (74)
High-density lipoprotein metabolism and the human embryo. (2010) (71)
Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia. (1986) (71)
Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. (2000) (70)
New molecular insights into CETP structure and function: a review (2012) (69)
Evaluation of Langerhans' cells in the cervical epithelium of women with cervical intraepithelial neoplasia. (1999) (67)
Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms. (2000) (66)
Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease. (2011) (65)
Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy[S] (2011) (63)
Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles. (1993) (62)
Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender. (1998) (61)
Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats. (1995) (60)
Cryo-electron microscopy of low density lipoprotein and reconstituted discoidal high density lipoprotein: imaging of the apolipoprotein moiety. (1997) (60)
Prebeta-1 HDL and coronary heart disease (2012) (60)
Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity (2005) (60)
Mechanisms of statin-induced myalgia assessed by physiogenomic associations. (2011) (59)
Isoelectric heterogeneity of the cofactor protein for lipoprotein lipase in human blood plasma. (1979) (58)
Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. (2012) (58)
Serum apolipoprotein A-I levels: relationship to lipoprotein lipid levels and selected demographic variables. (1982) (58)
Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. (1991) (56)
Effects of a 3-day fast and of ethanol on splanchnic metabolism of FFA, amino acids, and carbohydrates in healthy young men. (1976) (56)
Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption. (1994) (55)
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. (2008) (55)
Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia. (1991) (55)
Chylomicrons can inhibit endotoxin activity in vitro. (1991) (55)
A Multilocus Genotyping Assay for Cardiovascular Disease (1998) (55)
Apolipoprotein B (B-48) of rat chylomicrons is not a precursor of the apolipoprotein of low density lipoproteins. (1982) (54)
The Effect of Chronic Oral Antidiabetic Therapy on Insulin and Glucagon Responses to a Meal (1977) (52)
Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. (2008) (51)
Antigen-specific nonimmunoglobulin factor that neutralizes xenotropic virus is associated with mouse serum lipoproteins. (1977) (50)
High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture (2006) (48)
Effect of diet composition on metabolic adaptations to hypocaloric nutrition: comparison of high carbohydrate and high fat isocaloric diets. (1977) (47)
STUDIES OF CARBOHYDRATE METABOLISM IN IDIOPATHIC HYPERTRIGLYCERIDEMIA. (1965) (47)
Exome Sequencing in Suspected Monogenic Dyslipidemias (2015) (44)
Human renin gene BglI dimorphism associated with hypertension in two independent populations (1999) (44)
Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors (2005) (44)
Functional variants of the HMGA1 gene and type 2 diabetes mellitus. (2011) (44)
The effects of physical exercise on plasma prebeta-1 high-density lipoprotein. (2003) (44)
Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy (2010) (44)
Apolipoprotein is responsible for neutralization of xenotropic type C virus by mouse serum. (1979) (43)
Analysis of 17,576 Potentially Functional SNPs in Three Case–Control Studies of Myocardial Infarction (2008) (42)
Lack of association of lipoprotein(a) levels with coronary calcium deposits in asymptomatic postmenopausal women. (2000) (42)
Treatment of hypercholesterolemia. (1982) (41)
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders (2003) (40)
Subunit heterogeneity in human serum beta lipoprotein. (1970) (39)
A variant primary structure of apolipoprotein C-II in individuals of African descent. (1986) (38)
Splanchnic metabolism in von Gierke's disease (glycogenosis type I). (1969) (38)
Distribution of lipid-binding regions in human apolipoprotein B-100. (1989) (38)
Sex-related differences in the concentrations of apolipoprotein E in human blood plasma and plasma lipoproteins. (1983) (38)
Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity. (1991) (38)
Radiation inactivation of binding sites for high density lipoproteins in human fibroblast membranes. (1988) (36)
Detection of endotoxin in triglyceride-rich lipoproteins in vitro. (1991) (36)
Quantification of triglyceride transport in blood plasma: a critical analysis. (1975) (36)
Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B. (1986) (36)
Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1 Published, JLR Papers in Press, February 23, 2009. (2009) (35)
Structural domains of human apolipoprotein B-100. Differential accessibility to limited proteolysis of B-100 in low density and very low density lipoproteins. (1989) (35)
The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. (1999) (34)
Therapy of hyperlipidemic states. (1982) (34)
patient-oriented and epidemiological research An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients (2008) (34)
Relation of Plasma Lipid and Apoprotein Levels to Progressive Intimal Hyperplasia After Arterial Endarterectomy (1992) (34)
Neutralization of mouse xenotropic virus by lipoproteins involves binding to the virions. (1988) (34)
The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles. (2010) (32)
Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population. (2014) (32)
Identification and metabolic profiling of patients with lysosomal acid lipase deficiency. (2015) (32)
Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum. (1980) (31)
The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion (2006) (31)
New protein in human blood plasma, rich in proline, with lipid-binding properties. (1976) (31)
Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL Published, JLR Papers in Press, December 16, 2004. DOI 10.1194/jlr.M400304-JLR200 (2005) (31)
Contribution of carotenoids to the optical activity of human serum low-density lipoprotein. (1974) (31)
The Online Metabolic and Molecular Bases of Inherited Disease > 114 : Introduction : Structure and Metabolism of Plasma Lipoproteins (2017) (31)
Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression (2013) (31)
Ricin and lentil lectin-affinity chromatography reveals oligosaccharide heterogeneity of thyrotropin secreted by 12 human pituitary tumors. (1992) (30)
Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report. (1989) (29)
The effect of ligand heterogeneity on the Scatchard plot. Particular relevance to lipoprotein binding analysis. (1985) (29)
Stability of the apoprotein of human serum low density lipoprotein: absence of endogenous endopeptidase activity. (1975) (29)
Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL. (1992) (28)
Discrimination between subclasses of human high-density lipoproteins by the HDL binding sites of bovine liver. (1986) (28)
Hyperlipidemia and cardiovascular disease. (2012) (28)
Metabolic abnormalities and coronary heart disease risk in human immunodeficiency virus-infected adults. (2010) (28)
Galanin Preproprotein Is Associated With Elevated Plasma Triglycerides (2009) (27)
Intravenous thyrotropin (TSH)-releasing hormone releases human TSH that is structurally different from basal TSH. (1992) (27)
Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels (2011) (26)
Measurement of prebeta-1 HDL in human plasma by an ultrafiltration-isotope dilution technique. (1997) (26)
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia. (2009) (26)
Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties. (2014) (25)
Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia Published, JLR Papers in Press, December 30, 2005. (2006) (25)
Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease. (2008) (25)
Parotid secretory protein is an HDL-associated protein with anticandidal activity. (2005) (25)
Characterization and quantitation of apolipoproteins A-I and E of normal and cholesterol-fed guinea pigs. (1982) (25)
Prolonged effects of tumor necrosis factor-α on anterior pituitary hormone release (1995) (24)
Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease. (2014) (24)
Temperature dependence of the optical activity of human serum low density lipoprotein. The role of lipids. (1975) (24)
Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content. (1990) (24)
Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection? (1999) (23)
Plasma Lipoproteins: Structure and Metabolism (1977) (23)
[12] Isolation and characterization of apolipoprotein B-48 (1986) (23)
Medical management of hyperlipidemic states. (1994) (23)
Familial hypercholesterolaemia: cholesterol efflux and coronary disease (2016) (23)
ABSENCE OF THE B-100 APOLIPOPROTEIN (1981) (22)
Genetic variation in phospholipid transfer protein modulates lipoprotein profiles in hyperalphalipoproteinemia. (2008) (22)
Human apolipoprotein C-I: concentration in blood serum and lipoproteins. (1980) (21)
A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin. (1997) (21)
Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B. (1986) (21)
Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function. (2012) (21)
Differences in local conformation in human apolipoprotein B-100 of plasma low density and very low density lipoproteins as identified by cathepsin D. (1991) (20)
Circular dichroic spectra of apolipoprotein E in model complexes and cholesterol-rich lipoproteins: lipid contribution. (1984) (20)
Identification of apolipoprotein B100 polymorphisms that affect low-density lipoprotein metabolism: description of a new approach involving monoclonal antibodies and dynamic light scattering. (1995) (17)
Octreotide changes serum thyrotropin (TSH) glycoisomer distribution as assessed by lectin chromatography in a TSH macroadenoma patient. (1993) (17)
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus. (2021) (17)
Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects. (2009) (17)
Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia. (1993) (17)
Aberrant Hetero-Disulfide Bond Formation by the Hypertriglyceridemia-Associated p.Gly185Cys APOA5 Variant (rs2075291) (2014) (16)
Treatment of hypercholesterolemia. (1982) (16)
Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus. (2010) (16)
Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake. (2017) (16)
Isolation of subpopulations of high density lipoproteins: three particle species containing apoE and two species devoid of apoE that have affinity for heparin. (1997) (16)
Radiation inactivation of binding sites for high-density lipoproteins in human liver membranes. (1988) (15)
GOSR2 Lys67Arg is associated with hypertension in whites. (2009) (15)
Association between Regulator of G Protein Signaling 9–2 and Body Weight (2011) (15)
Vitamin E-enriched lipoproteins increase longevity of neurons in vitro. (1981) (15)
Lipid and Lipoprotein Metabolism (2006) (15)
Familial hypercholesterolemia in children: treatment with p-aminosalicylic acid. (1978) (14)
CONDUCTION ANESTHESIA USING DIPHENHYDRAMINE HYDROCHLORIDE. (1964) (14)
Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia[S] (2019) (14)
The complement system in cryoglobulinaemia. Interaction with immunoglobulins and lipoproteins. (1975) (14)
Normocholesterolemic dysbetalipoproteinemia with xanthomatosis. (1979) (14)
Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia (2020) (13)
beta-Carotene as a probe of lipid domains of reconstituted human plasma low-density lipoprotein: induced circular dichroism. (1980) (13)
Improved separation of high-molecular-weight proteins by preparative sodium dodecyl sulfate--gel electrophoresis: application to apolipoprotein B. (1980) (13)
Isolation and characterization of apolipoprotein B-48. (1986) (13)
Prolonged effects of tumor necrosis factor-alpha on anterior pituitary hormone release. (1995) (12)
Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients. (2011) (12)
Secondary structure and thermal behavior of trypsin-treated low-density lipoproteins from human serum, studied by circular dichroism. (1983) (11)
Levels of prebeta-1 high-density lipoprotein are elevated in 3 phenotypes of dyslipidemia. (2017) (11)
Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects. (1999) (11)
Endocrine and metabolic alterations with food and water deprivation. (1977) (11)
[30] Circular dichroism of lipoprotein lipids (1986) (11)
Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding. (2002) (11)
Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination. (1987) (10)
Hb leiden‐β° thalassemia in a chinese with severe hemolytic anemia (1977) (10)
Transfer of mouse anti-xenotropic virus neutralizing factor to human lipoproteins (1982) (10)
Thermal behavior of cores of human serum triglyceride-rich lipoproteins: a study of induced circular dichroism of beta-carotene. (1984) (10)
The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients. (1995) (10)
Sebelipase alfa for lysosomal acid lipase deficiency: 5‐year treatment experience from a phase 2 open‐label extension study (2020) (10)
Impact of a 4q25 Genetic Variant in Atrial Flutter and on the Risk of Atrial Fibrillation After Cavotricuspid Isthmus Ablation (2014) (10)
Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. (2003) (10)
Secondary structure in very low density and intermediate density lipoproteins of human serum. (1979) (9)
Scission of human apolipoprotein B-100 by kallikrein: characterization of the cleavage site. (1986) (9)
Human apolipoprotein CI (apoC1) gene locus: DraI dimorphic site. (1987) (9)
Molecular weight distributions of polydisperse systems: application to very low density lipoproteins. (1978) (9)
Hemoglobin Tak in a newborn Malay. (1977) (9)
Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: A report from the childhood cancer survivor study (2012) (9)
Elevated Baseline Triglyceride Levels Modulate Effects of HMGCoA Reductase Inhibitors on Plasma Lipoproteins (2001) (9)
Effect of thyroid hormone deficiency on glycosylation of rat TSH secreted in vitro. (1993) (8)
Genetic Variation in PLTP Modulates Lipoprotein Profiles in Hyperalphalipoproteinemia (8)
The apolipoprotein C‐II variant apoC‐IILys19→Thr is not associated with dyslipidemia in an affected kindred (1994) (8)
Apolipoprotein A‐II Active or Passive Role in Familial Combined Hyperlipidemia (2003) (8)
Moderate statin treatment reduces prebeta-1 high-density lipoprotein levels in dyslipidemic patients. (2017) (8)
Speciation of HDL. (1986) (8)
Emerging roles of HDL in immune function. (2018) (8)
Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes. (2011) (7)
Novel genetic markers for structural coronary artery disease, myocardial infarction, and familial combined hyperlipidemia: candidate and genome scans of functional SNPs (2004) (7)
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. Commentary (2002) (7)
The apolipoprotein B Q3405E polymorphism has no effect on its low-density-lipoprotein receptor binding affinity (1996) (7)
Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients. (2014) (7)
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (2010) (6)
Human apolipoprotein CI (ApoC1) gene locus: BglI dimorphic site. (1987) (6)
Abstract 12252: Effects of the Cholesteryl Ester Transfer Protein Inhibitor, Evacetrapib, Administered as Monotherapy or in Combination With Statins on Cholesterol Efflux and HDL Particles in Patients With Dyslipidemia (2014) (6)
Determinants of kallikrein proteolysis of apolipoprotein B‐100 in human blood plasma (1988) (5)
Pancreatic alpha and beta cell function in familial dysbetalipoproteinemia. (1980) (5)
Genetic analysis of a polymorphism in the human apoA-V gene Published, JLR Papers in Press, April 1, 2003. DOI 10.1194/jlr.M200480-JLR200 (2003) (5)
Ancestry-specific profiles of genetic determinants of severe hypertriglyceridemia. (2020) (5)
Synergism in Drug Treatment of Familial Hypercholesterolemia (1980) (5)
Niacin--the long and the short of it. (1991) (5)
Apolipoprotein and size heterogeneity in human umbilical cord blood low density lipoproteins. (1983) (5)
Treatment of hyperlipidemia. (1990) (5)
Clonal hematopoiesis is driven by aberrant activation of TCL1A (2021) (5)
Expression of Reverse Cholesterol Transport Proteins SR-BI, SR-BII and ABCA1 in the Human Retinal Pigment Epithelium (2003) (4)
Metabolism of Lipid and Protein Components of Triglyceride-Rich Lipoproteins in Rats and Humans (1976) (4)
Splanchnic metabolism in healthy young men given clofibrate (1970) (4)
Levels of Prebeta‐1 High‐Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta‐Analysis (2021) (4)
DraI RFLP in the human apolipoprotein AI-CIII-AIV gene complex. (1986) (4)
Binding of thyrotropin to lentil lectin is unchanged by thyrotropin-releasing hormone administration in three patients with thyrotropin-producing pituitary adenomas. (1992) (4)
Polymorphisms and Noncardioembolic Stroke in Three Case-Control Studies (2011) (4)
Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067. (2007) (4)
JCL Roundtable: diagnosis of severe familial hypercholesterolemia. (2013) (3)
Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis (2019) (3)
Characterization of apolipoprotein B-containing lipoproteins. (1986) (3)
Abstract 20918: Cytokines Involved in Arterial Wall Inflammation Are Transported by High Density Lipoprotein Particles (2017) (3)
Multi-ethnic genome-wide association study for atrial fibrillation (2018) (3)
Circular dichroism of lipoprotein lipids. (1986) (3)
Editorial: Early prevention of atherosclerosis. (1975) (3)
Infectious basophilia? (2016) (2)
New horizons in lipid management. (2013) (2)
Author response: An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish (2015) (2)
NORMOTRIGLYCERIDEMIC ABETALIPOPROTEINEMIA - CLINICAL AND BIOCHEMICAL FEATURES OF A NEW SYNDROME (1977) (2)
Plasma lipoproteins and their receptors (1991) (2)
Machine learning and statistical approaches for classification of risk of coronary artery disease using plasma cytokines (2020) (2)
Aggressive medical therapy for the prevention and treatment of coronary artery disease. (1997) (2)
NcoI dimorphic site located 8kb 3' to the human apolipoprotein AIV (APOA4) gene. (1988) (2)
1155 NORMOTRIGLYCERIDEMIC ABETALIPOPROTEINEMIA: FATE OF APOLIPOPROTEIN B OF CHYLOMICRONS (1981) (2)
Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method (2019) (2)
Does hypertriglyceridemia present an indication for pioglitazone therapy in diabetes? (2002) (2)
Safety findings from 3 trials of treatment with sebelipase alfa in children and adults with lysosomal acid lipase deficiency (2016) (2)
Sterol biosynthesis under the influence of a thyroxine analog (3,5-diiodothyroacetic acid). (1962) (1)
1103-194 Identification of novel genetic markers associated with risk of myocardial infarction from a genomic scale scan of putative functional polmorphisms (2004) (1)
Familial Chylomicronemia Syndrome (FCS) Patients Recruited to the APPROACH Trial of Volanesorsen Therapy are Representative of Subjects with FCS (2017) (1)
Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia (1979) (1)
725 Variants of adipocyte genes affecting free fatty acid flux in patients with non alcoholic fatty liver disease (2003) (1)
BINDING OF HDL AND rHDL TO THE HDL RECEPTOR SR-BI: EFFECT OF LIPID ASSOCIATION AND APOA-I MUTATIONS ON RECEPTOR BINDING (2000) (1)
HDL cholesterol efflux capacity and cardiovascular events. (2015) (1)
Biochemical Analysis of the LPL Truncation Variant, LPL S447X Reveals Increased Lipoprotein Uptake (2018) (1)
Hb Leiden-beta (0) thalassemia in a Chinese with severe hemolytic anemia. (1977) (1)
A variant of the microsomal triglyceride transfer protein gene in patients with non-alcoholic steatohepatitis (2003) (1)
Identifying Cases of Cholesteryl Ester Storage Disease in a Tertiary Lipid Clinic (2013) (1)
A polymorphic PstI site in intron 2 of the human apolipoprotein C-II gene detected by polymerase chain reaction (1992) (1)
Homozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE-FH Registry† (2019) (1)
Associated With the ApolipoproteinC-III Content of ApoB Particles Among Those With Diabetes Mellitus (2004) (1)
Apolipoprotein E and neurocognitive function--in reply. (2015) (1)
Abstract 18073: Prebeta-1 High Density Lipoprotein Levels are Elevated in Dyslipidemic Phenotypes (2012) (0)
Structures of high-mannose and complex oligosaccharides of mouse TSH and free alpha-subunits after in vitro incubation of thyrotropic tissue with TRH. (1992) (0)
Natural History and Biology of Atherosclerosis (1982) (0)
Elastin Degradation and Lung Function Deterioration with Remote Secondhand Tobacco Smoke Exposure in Never-smokers. (2022) (0)
Exploratory data analysis of hyperlipidemia on the Macintosh: Software tools for analysis of biochemical, clinical, and genetic variables in 1677 consecutive lipid clinic patients (1993) (0)
Aggressive medical therapy for the prevention and treatment of coronary artery disease. (1998) (0)
Abstract 4113: Genetic Risk of Coronary Heart Disease in the Atherosclerosis Risk in Communities (ARIC) study: Application of a Genetic Risk Score (2006) (0)
Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia (2022) (0)
Implementation of PCA enabled Support Vector Machine using cytokines to differentiate smokers versus nonsmokers. (2021) (0)
TaqI and XbaI RFLPs detected with a human apo IV (Apo4) cDNA probe. (1986) (0)
Efficacy and Safety of Sebelipase Alfa in Children and Adults with Lysosomal Acid Lipase Deficiency: Results of a Phase 3 Trial† (2015) (0)
Structural variation across 138,134 samples in the TOPMed consortium (2023) (0)
Black Tea and Toast (1978) (0)
120 ASSOCIATION OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN −493G/T POLYMORPHISM WITH LIPID METABOLISM AND MICROVASCULAR COMPLICATIONS IN TYPE 2 DIABETIC PATIENTS. (2007) (0)
Lipoprotein (a) does not correlate with coronary calcium deposits in postmenopausal women (1998) (0)
Lowering Lipids Improves Coronary Arterial Anatomy-Reply (1991) (0)
Running title: Stitziel et al., Exome Sequencing in Monogenic Dyslipidemias (2015) (0)
Abstract P201: Separation of Postprandial Lipoproteins: Purification of Chylomicrons Using an ApoB100 Immunoaffinity Method (2019) (0)
Chapter 51 – Lipoprotein Disorders (2015) (0)
Sex Bias in Cytokines Transported by High‐Density Lipoproteins in Patients with Coronary Artery Disease (2018) (0)
LOWERING LIPIDS IMPROVES CORONARY ARTERIAL ANATOMY. AUTHORS' REPLIES (1991) (0)
4P-1018 Parotid secretory protein is associated with HDL and expressed in respiratory epithelium, keratinocytes, sebaceous glands, and gonads (2003) (0)
Sebelipase Alfa Improves Dyslipidemia in Patients with Cholesteryl Ester Storage Disease (2013) (0)
Emerging molecular strategies for management of dyslipidemias. (2015) (0)
When to treat hyperlipidemia. (1988) (0)
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis (2023) (0)
Apolipoprotein a-v: A determinant of plasma triglyceride levels (2003) (0)
Drs malloy and kane respond. (1992) (0)
Xenosterolemia: emerging molecular and clinical insights. (2017) (0)
Th-P16:331 Assessment of lipoprotein profiles (Alps study) and antioxidant activity in healthy subjects treated with AGI-1067 (2006) (0)
Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry. (2023) (0)
Long term safety and clinical activity of SBC-102, a recombinant human lysosomal acid lipase (rhLAL), in patients with late onset LAL deficiency (2013) (0)
Congenital absence of apolipoprotein E and neurological function-reply. (2014) (0)
NOVEL GENETIC MARKERS ASSOCIATED WITH RISK OF MYOCARDIAL INFARCTION FROM A GENOMIC SCALE SCAN OF PUTATIVE FUNCTIONAL POLYMORPHISMS (2004) (0)
CLN8: AN ATORVASTATIN-SPECIFIC MARKER FOR COMMON MYALGIA (2014) (0)
Characteristics of human lipoprote immunosorption of apolipoprotein i (2016) (0)
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Lack of Support for the Association Between GAD 2 Polymorphisms and Severe Human Obesity Permalink (2005) (0)
Machine Learning and Statistical Approaches for Classification of Risk of 1 Coronary Artery Disease using Plasma Cytokines . 2 (2020) (0)
Abstract: 37 PHYSIOGENOMIC CONTOURS OF STATIN SAFETY AND EFFICACY (2009) (0)
Apolipoprotein AII Active or Passive Role in Familial Combined Hyperlipidemia (2003) (0)
Lipoproteins and amyloid vascular disease. (2016) (0)
Bsm I RFLP at the human apolipoprotein AI-CIII gene complex locus. (1988) (0)
Apolipoprotein E Containing High Density Lipoproteins can Function as Preferential Acceptors for Retinal Pigment Epithelium Cell Digested Photoreceptor Outer Segment Lipids (2003) (0)
STATIN TREATMENT REDUCES PEBETA-1 HDL LEVELS IN DYSLIPIDEMIC PATIENTS (2015) (0)
Application of Machine Learning Ensemble Super Learner for analysis of the cytokines transported by high density lipoproteins (HDL) of smokers and nonsmokers (2021) (0)
Structural variation across 138,134 samples in the TOPMed consortium (2023) (0)
Basal Reverse Cholesterol Transport of Retinal Pigment Epithelium Cell Digested Photoreceptor Outer Segment Lipids (2004) (0)
Gene Variants in Caveolin-1 and Caveolin-2 in Patients with Idiopathic Pulmonary Arterial Hypertension (2008) (0)
Machine learning and statistical approaches for classification of risk of coronary artery disease using plasma cytokines (2021) (0)
Endothelial dysfunction in a man with a disruptive mutation in the estrogen receptor gene (1997) (0)
242 Emerging roles of high-density lipoproteins in fertility (2018) (0)
The role of the succinate-glycine cycle in glutamate synthesis (1957) (0)
In Memoriam: Richard J. Havel (1925–2016) (2016) (0)
Control or Reversal of Atherosclerosis Through Therapy of Lipid Disorders (1984) (0)
Emerging roles of qualitative properties of lipoproteins in atherosclerosis. (2014) (0)
Identification, lipoprotein profiling and treatment of patients with lysosomal acid lipase deficiency (2014) (0)
APOL1 Risk Variants Associate with the Prevalence of Stroke in African American Current and Past Smokers (2023) (0)
Needed: a better understanding of the antiatherogenic properties of HDL. (2013) (0)
Lipoprotein disorders (2020) (0)

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