Joram Piatigorsky
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Biology
Joram Piatigorsky's Degrees
- PhD Biochemistry University of California, Berkeley
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(Suggest an Edit or Addition)Joram Piatigorsky's Published Works
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Published Works
- Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. (1988) (750)
- Lens differentiation in vertebrates. A review of cellular and molecular features. (1981) (594)
- The cellular basis of corneal transparency: evidence for 'corneal crystallins'. (1999) (485)
- Enzyme/crystallins: Gene sharing as an evolutionary strategy (1989) (372)
- Expression of the murine alpha B-crystallin gene is not restricted to the lens (1989) (356)
- Recruitment of enzymes as lens structural proteins. (1987) (326)
- The recruitment of crystallins: new functions precede gene duplication (1991) (323)
- Lens development and crystallin gene expression: many roles for Pax‐6 (1996) (295)
- Gene sharing by delta-crystallin and argininosuccinate lyase. (1988) (242)
- Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. (1985) (219)
- Squid Pax-6 and eye development. (1997) (210)
- Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron (1983) (201)
- Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. (1995) (185)
- Oxidative Stress Increases Production of -Amyloid Precursor Protein and -Amyloid (A) in Mammalian Lenses, and A Has Toxic Effects on Lens Epithelial Cells (*) (1996) (176)
- Oncogenesis of the lens in transgenic mice. (1987) (176)
- Modulation of myocilin/TIGR expression in human trabecular meshwork. (1999) (175)
- Role of Pax genes in eye evolution: a cnidarian PaxB gene uniting Pax2 and Pax6 functions. (2003) (174)
- Gene sharing in lens and cornea: facts and implications (1998) (167)
- Requirement for Pax6 in corneal morphogenesis: a role in adhesion (2003) (161)
- A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins (1994) (158)
- Tau-crystallin/alpha-enolase: one gene encodes both an enzyme and a lens structural protein (1988) (156)
- Multiple and Additive Functions of ALDH3A1 and ALDH1A1 (2007) (155)
- Chicken homeobox gene prox 1 related to Drosophila prospero is expressed in the developing lens and retina (1996) (151)
- Expression of the α‐Crystallin/Small Heat‐Shock Protein/Molecular Chaperone Genes in the Lens and other Tissues (1994) (150)
- Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. (2000) (149)
- Dual Roles for Pax-6: a Transcriptional Repressor of Lens Fiber Cell-Specific β-Crystallin Genes (1998) (147)
- Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site (1995) (144)
- Retinoic acid X receptor in the diploblast, Tripedalia cystophora. (1998) (144)
- Multifunctional Lens Crystallins and Corneal Enzymes: More than Meets the Eye (1998) (138)
- Alpha-crystallin/small heat shock protein has autokinase activity. (1994) (135)
- ALDH3A1: a corneal crystallin with diverse functions. (2007) (134)
- Lens crystallins. Innovation associated with changes in gene regulation. (1992) (133)
- Lens crystallins and their gene families (1984) (130)
- Lens Crystallins of Invertebrates (1996) (128)
- Conditional Deletion of the Mouse Klf4 Gene Results in Corneal Epithelial Fragility, Stromal Edema, and Loss of Conjunctival Goblet Cells (2006) (127)
- Assembly of the cnidarian camera-type eye from vertebrate-like components (2008) (121)
- Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. (1995) (116)
- Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes (1990) (110)
- Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress. (1996) (110)
- Human αB-crystallin gene and preferential promoter function in lens (1990) (109)
- Mafs, Prox1, and Pax6 Can Regulate Chicken βB1-Crystallin Gene Expression* (2004) (108)
- Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia. (1985) (108)
- Regulation of protein synthesis, intracellular electrolytes and cataract formation in vitro (1977) (104)
- CELL ELONGATION IN THE CULTURED EMBRYONIC CHICK LENS EPITHELIUM WITH AND WITHOUT PROTEIN SYNTHESIS (1972) (102)
- Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells. (1986) (102)
- Enigma of the Abundant Water-Soluble Cytoplasmic Proteins of the Cornea: The “Refracton” Hypothesis (2001) (101)
- Gene and protein structure of a β-crystallin polypeptide in murine lens: relationship of exons and structural motifs (1983) (100)
- Lens crystallins and their genes: diversity and tissue‐specific expression (1989) (96)
- Differentiation of lens fibers in explanted embryonic chick lens epithelia. (1973) (95)
- Expression of the murine alpha B-crystallin gene in lens and skeletal muscle: identification of a muscle-preferred enhancer (1991) (92)
- Protein synthesis and ultrastructure during the formation of embryonic chick lens fibers in vivo and in vitro. (1972) (92)
- Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells. (1996) (91)
- Regulation of the murine alpha B-crystallin/small heat shock protein gene in cardiac muscle (1995) (86)
- Transketolase Is a Major Protein in the Mouse Cornea* (1996) (84)
- Taxon-specific recruitment of enzymes as major soluble proteins in the corneal epithelium of three mammals, chicken, and squid. (1992) (83)
- Postnatal gene expression in the normal mouse cornea by SAGE. (2004) (83)
- Squid glutathione S-transferase. Relationships with other glutathione S-transferases and S-crystallins of cephalopods. (1993) (83)
- Gene Sharing and Evolution: The Diversity of Protein Functions (2007) (81)
- Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress. (2005) (79)
- Pax-6 and αB-crystallin/Small Heat Shock Protein Gene Regulation in the Murine Lens INTERACTION WITH THE LENS-SPECIFIC REGIONS, LSR1 AND LSR2* (1996) (77)
- A change in permeability and uptake of [14C]uridine in response to fertilization in Strongylocentrotus purpuratus eggs. (1965) (77)
- Involvement of Retinoic Acid/Retinoid Receptors in the Regulation of Murine αB-crystallin/Small Heat Shock Protein Gene Expression in the Lens* (1998) (76)
- Spatial and temporal activity of the αB‐crystallin/small heat shock protein gene promoter in transgenic mice (1996) (75)
- Insulin initiation of lens fiber differentiation in culture: elongation of embryonic lens epithelial cells. (1973) (75)
- δ- and β-crystallin mRNA levels in the embryonic and posthatched chicken lens: Temporal and spatial changes during development (1985) (74)
- THE EFFECT OF DESICCATION AND ANAEROBIC CONDITIONS ON THE BEHAVIOUR, SURVIVAL AND GENERAL METABOLISM OF THREE COMMON CIRRIPEDES (1963) (74)
- Disruption of anterior segment development by TGF‐β1 overexpression in the eyes of transgenic mice (2002) (73)
- Gamma-crystallin family of the mouse lens: structural and evolutionary relationships. (1984) (72)
- Cubozoan jellyfish: an Evo/Devo model for eyes and other sensory systems. (2004) (72)
- Expression of βB2-Crystallin mRNA and Protein in Retina, Brain, and Testis (2000) (71)
- Molecular weight and subunit structure of delta-crystallin from embryonic chick lens fibers. (1974) (71)
- Loss during development of the ability of chick embryonic lens cells to elongate in culture: inverse relationship between cell division and elongation. (1972) (70)
- Aldehyde dehydrogenase-derived omega-crystallins of squid and octopus. Specialization for lens expression. (1993) (70)
- Regulation of the murine αA-crystallin promoter in transgenic mice (1990) (70)
- Conversion from oligomers to tetramers enhances autophosphorylation by lens alpha A-crystallin. Specificity between alpha A- and alpha B-crystallin subunits. (1995) (69)
- Abnormal lens morphogenesis and ectopic lens formation in the absence of β‐catenin function (2007) (69)
- The murine alpha B-crystallin/small heat shock protein enhancer: identification of alpha BE-1, alpha BE-2, alpha BE-3, and MRF control elements (1993) (66)
- Sequence of the chicken delta 2 crystallin gene and its intergenic spacer. Extreme homology with the delta 1 crystallin gene. (1986) (65)
- Transketolase Haploinsufficiency Reduces Adipose Tissue and Female Fertility in Mice (2002) (65)
- Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice (1996) (65)
- The complete sequence of the chicken delta 1 crystallin gene and its 5' flanking region. (1985) (64)
- Identification of candidate Klf4 target genes reveals the molecular basis of the diverse regulatory roles of Klf4 in the mouse cornea. (2008) (64)
- Lens crystallins of invertebrates--diversity and recruitment from detoxification enzymes and novel proteins. (1996) (64)
- alpha A-crystallin messenger RNA of the mouse lens: more noncoding than coding sequences. (1982) (63)
- Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein. (1999) (63)
- Review: A case for corneal crystallins. (2000) (63)
- Evidence for positive and negative regulation in the promoter of the chicken δ1-crystallin gene (1988) (63)
- Crystallins of the octopus lens. Recruitment from detoxification enzymes. (1991) (62)
- LENS CELL ELONGATION IN VITRO AND MICROTUBULES (1975) (61)
- Characterization of squid crystallin genes. Comparison with mammalian glutathione S-transferase genes. (1992) (61)
- Truncated forms of Pax-6 disrupt lens morphology in transgenic mice. (2000) (61)
- Differential metabolism and leakage of protein in an inherited cataract and a normal lens cultured with ouabain (1978) (60)
- Quantitation of delta-crystallin messenger RNA during lens induction in chick embryos. (1976) (59)
- Omega -crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin. (2000) (59)
- δ-Crystallin mRNA in chick lens cells: mRNA accumulates during differential stimulation of δ-crystallin synthesis in cultured cells (1976) (58)
- Structurally Normal Corneas in Aldehyde Dehydrogenase 3a1-Deficient Mice (2002) (58)
- Rates of protein synthesis in explanted embryonic chick lens epithelia: differential stimulation of delta-crystallin synthesis. (1975) (57)
- Orientation-dependent Influence of an Intergenic Enhancer on the Promoter Activity of the Divergently Transcribed Mouse Shsp/αB-crystallin andMkbp/HspB2 Genes* (2002) (57)
- Analysis of the mouse gamma-crystallin gene family: assignment of multiple cDNAs to discrete genomic sequences and characterization of a representative gene. (1984) (57)
- Chicken beta B1-crystallin gene expression: presence of conserved functional polyomavirus enhancer-like and octamer binding-like promoter elements found in non-lens genes (1991) (57)
- Identification of a lens-specific regulatory region (LSR) of the murine αB-crystallin gene (1994) (57)
- Preferential conservation of the globular domains of the beta A3/A1-crystallin polypeptide of the chicken eye lens. (1986) (56)
- Aldehyde dehydrogenase class 3 expression: identification of a cornea-preferred gene promoter in transgenic mice. (1997) (55)
- Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development (2009) (54)
- Interaction between two different regulatory elements activates the murine alpha A-crystallin gene promoter in explanted lens epithelia (1987) (52)
- The cellular eye lens and crystallins of cubomedusan jellyfish (1989) (52)
- Structure and alternate tissue-preferred transcription initiation of the mouse alpha B-crystallin/small heat shock protein gene. (1994) (52)
- Lens-specific promoter activity of a mouse gamma-crystallin gene. (1985) (52)
- Stimulation by insulin of cell elongation and microtubule assembly in embryonic chick-lens epithelia. (1973) (51)
- Evidence for Gelsolin as a Corneal Crystallin in Zebrafish* (2000) (51)
- Isolation and In Vitro Translation of δ-Crystallin mRNA from Embryonic Chick Lens Fibers (1974) (50)
- Human alpha B-crystallin gene and preferential promoter function in lens. (1990) (50)
- Structure and expression of the scallop Omega-crystallin gene. Evidence for convergent evolution of promoter sequences. (2002) (49)
- Glutathione S-transferase and S-crystallins of cephalopods: Evolution from active enzyme to lens-refractive proteins (1995) (49)
- Phosphorylations of αA- and αB-crystallin (1998) (48)
- Differential display detects altered gene expression between cataractous and normal human lenses. (1998) (48)
- J3-crystallin of the jellyfish lens: Similarity to saposins (2001) (48)
- J1-crystallins of the cubomedusan jellyfish lens constitute a novel family encoded in at least three intronless genes. (1993) (48)
- Resolution of two distinct embryonic chick delta-crystallin bands by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate and urea. (1977) (47)
- Multiple gamma-crystallins of the mouse lens: fractionation of mRNAs by cDNA cloning. (1982) (47)
- Expression of duck lens delta-crystallin cDNAs in yeast and bacterial hosts. Delta 2-crystallin is an active argininosuccinate lyase. (1991) (46)
- delta-Crystallin gene expression in embryonic chick lens epithelia cultured in the presence of insulin. (1977) (46)
- Abundant mRNAs in the squid light organ encode proteins with a high similarity to mammalian peroxidases. (1993) (46)
- Comparative and evolutionary aspects of delta-crystallin in the vertebrate lens. (1979) (45)
- Intracellular ions, protein metabolism, and cataract formation. (1980) (45)
- Structure and expression of the duck α-enolase/τ-crystallin-encoding gene (1991) (45)
- Development of characterization of a immortal and differentiated murine trabecular meshwork cell line. (1999) (45)
- Differential synthesis and degradation of protein in the hereditary Philly mouse cataract. (1980) (45)
- Degradation of δ-crystallin mRNA in the lens fiber cells of the chicken (1982) (44)
- Chicken lens crystallin DNA sequences show at least two δ-crystallin genes (1980) (44)
- Gene conversion and splice-site slippage in the argininosuccinate lyases/delta-crystallins of the duck lens: members of an enzyme superfamily. (1990) (43)
- Molecular cloning and partial characterization of delta-crystallin cDNA sequences in a bacterial plasmid. (1979) (43)
- cDNA and deduced protein sequence for the beta B1-crystallin polypeptide of the chicken lens. Conservation of the PAPA sequence. (1986) (43)
- Influence of individual amino acids on uptake and incorporation of valine, glutamic acid and arginine by unfertilized and fertilized sea urchin eggs. (1966) (43)
- Ectopic expression of AP-2alpha transcription factor in the lens disrupts fiber cell differentiation. (2002) (43)
- Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor. (2002) (42)
- Evolution and diversity of the crystallins. Nucleotide sequence of a beta-crystallin mRNA from the mouse lens. (1982) (42)
- Chicken beta B1 crystallin: gene sequence and evidence for functional conservation of promoter activity between chicken and mouse. (1995) (42)
- Tissue-specific expression of the chicken alpha A-crystallin gene in cultured lens epithelia and transgenic mice. (1989) (41)
- Characterization and enzyme activity of argininosuccinate lyase/delta-crystallin of the embryonic duck lens. (1996) (41)
- beta-Crystallins of the adult chicken lens: relatedness of the polypeptides and their aggregates. (1980) (40)
- Adaptive differences in the structure and macromolecular compositions of the air and water corneas of the “four‐eyed” fish (Anableps anableps) (2003) (40)
- Murine transcription factor alpha A-crystallin binding protein I. Complete sequence, gene structure, expression, and functional inhibition via antisense RNA. (1995) (40)
- Lens cataract formation and reversible alteration in crystallin synthesis in cultured lenses. (1977) (40)
- Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation. (2011) (40)
- Crystallin genes: specialization by changes in gene regulation may precede gene duplication. (2003) (40)
- Crystallin genes: specialization by changes in gene regulation may precede gene duplication (2004) (40)
- Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues. (1994) (39)
- Translational regulation of δ-crystallin synthesis during lens development in the chicken embryo (1981) (39)
- A pseudo-exon in the functional humanαA-crystallin gene (1989) (38)
- Transketolase Gene Expression in the Cornea Is Influenced by Environmental Factors and Developmentally Controlled Events (2000) (38)
- Beta-crystallin mRNAs: differential distribution in the developing chicken lens. (1981) (38)
- Protein-DNA interactions of the mouse alpha A-crystallin control regions. Differences between expressing and non-expressing cells. (1993) (38)
- Expression of betaB(2)-crystallin mRNA and protein in retina, brain, and testis. (2000) (38)
- Functional redundancy of the DE-1 and αA-CRYBP1 regulatory sites of the mouse αA-crystallin promoter (1993) (37)
- Protein synthesis and development in the absence of cytoplasmic RNA synthesis in nonnucleate egg fragments and embryos of sea urchins: effect of ethidium bromide. (1971) (37)
- Gene expression and genetic engineering in the lens. Friedenwald lecture. (1987) (37)
- RNA-and protein-synthesizing capacity of isolated oocytes of the sea urchin Lytechinus pictus. (1967) (37)
- Evidence for neutral and selective processes in the recruitment of enzyme-crystallins in avian lenses. (1990) (37)
- Adaptive evolution of small heat shock protein/ αB-crystallin promoter activity of the blind subterranean mole rat, Spalax ehrenbergi (2002) (37)
- Assignment of the alpha B-crystallin gene to human chromosome 11. (1989) (36)
- τ-crystallin from the turtle lens: Purification and partial characterization (1985) (36)
- Regulation of corneal epithelial barrier function by Kruppel-like transcription factor 4. (2011) (35)
- Lens-specific activity of the mouse αA-crystallin promoter in the absence of a TATA box: functional and protein binding analysis of the mouse (αA-crystallin PE1 region (1995) (35)
- Lens‐preferred activity of chicken δ1‐ and δ2‐crystallin enhancers in transgenic mice and evidence for retinoic acid‐responsive regulation of the δ1‐crystallin gene (1997) (35)
- Regulation of vimentin gene expression in the ocular lens. (1990) (35)
- Enhancer-independent promoter activity of the mouse αB-crystallin/small heat shock protein gene in the lens and cornea of transgenic mice (2000) (34)
- Differential use of the regulatory elements of the αB-crystallin enhancer in cultured murine lung (MLg), lens (αTN4-1) and muscle (C2C12) cells (1995) (34)
- Recruitment of enzymes and stress proteins as lens crystallins. (1994) (34)
- Transcription and site-specific hypomethylation of the delta-crystallin genes in the embryonic chicken lens. (1981) (34)
- Binding of tissue-specific forms of αA-CRYBP1 to their regulatory sequence in the mouse αA-crystallin-encoding gene: double-label immunoblotting of UV-crosslinked complexes (1993) (33)
- Gene Sharing, Lens Crystallins and Speculations on an Eye/Ear Evolutionary Relationship1 (2003) (33)
- Primary structure and lens-specific expression of genes for an intermediate filament protein and a β-tubulin in cephalopods (1993) (33)
- Recommendations for crystallin nomenclature. (1989) (33)
- Structural and functional evidence for differential promoter activity of the two linked delta‐crystallin genes in the chicken. (1985) (33)
- Transcriptional regulation of the mouse αA-crystallin gene: Binding of USF to the -7/+5 region (1997) (32)
- Alternative splicing of alpha A-crystallin RNA. Structural and quantitative analyses of the mRNAs for the alpha A2- and alpha Ains-crystallin polypeptides. (1984) (32)
- Serial analysis of gene expression (SAGE) in the rat limbal and central corneal epithelium. (2006) (32)
- Lens-specific expression of a chicken beta A3/A1-crystallin promoter fragment in transgenic mice. (1996) (32)
- Functional elements DE2A, DE2B, and DE1A and the TATA box are required for activity of the chicken alpha A-crystallin gene in transfected lens epithelial cells. (1993) (32)
- Persistence of crystallin messenger RNA's with reduced translation in hereditary cataracts in mice. (1980) (31)
- Ancestry of Photic and Mechanic Sensation? (2005) (31)
- Gene expression of the mouse corneal crystallin Aldh3a1: activation by Pax6, Oct1, and p300. (2008) (31)
- The mouse beta B1-crystallin promoter: strict regulation of lens fiber cell specificity. (2001) (30)
- The chicken βA4- and βB1-crystallin-encoding genes are tightly linked (1995) (30)
- Regulation of alphaA-crystallin gene expression. Lens specificity achieved through the differential placement of similar transcriptional control elements in mouse and chicken. (1999) (30)
- Evidence against γ-crystallin DNA or RNA sequences in the chicken (1984) (29)
- Convergent evolution of crystallin gene regulation in squid and chicken: The AP-1/ARE connection (1994) (28)
- The chicken delta-crystallin gene family. Two genes of similar structure in close chromosomal approximation. (1984) (28)
- Diversity of beta-crystallin mRNAs of the chicken lens. Hybridization analysis with cDNA clones. (1983) (27)
- Expression of the δ-crystallin genes in the embryonic chicken lens (1988) (27)
- Complete nucleotide sequence of the chicken αA-crystallin gene and its 5' flanking region (1987) (26)
- Cubozoan crystallins: evidence for convergent evolution of pax regulatory sequences (2008) (26)
- Partial dissociation and renaturation of embryonic chick delta-crystallin. Characterization by ultracentrifugation and circular dichroism. (1977) (26)
- Duplicated gelsolin family genes in zebrafish: a novel scinderin‐like gene (scinla) encodes the major corneal crystallin (2007) (26)
- Sequence and Expression of Chicken βA2- and βB3-crystallins (1996) (26)
- Cell elongation and -crystallin synthesis without RNA synthesis in cultured early embryonic chick lens epithelia. (1973) (26)
- Selective loss of a family of gene transcripts in a hereditary murine cataract. (1985) (26)
- Comparison of two delta-crystallin genes in the chicken. (1980) (26)
- A role for chromosomal protein HMGN1 in corneal maturation. (2006) (25)
- The control of δ-crystallin gene expression during lens cell development: Dissociation of cell elongation, cell division, δ-crystallin synthesis, and δ-crystallin mRNA accumulation (1977) (25)
- Preferential Transcription of Rabbit Aldh1a1 in the Cornea: Implication of Hypoxia-Related Pathways (2004) (25)
- Structure and lens expression of the gene encoding chicken βA3/A1-crystallin (1992) (25)
- Crystallin synthesis and crystallin mRNAs in galactosemic rat lenses. (1982) (25)
- Differential expression of the two δ‐crystallin genes in lens and non‐lens tissues: Shift favoring δ2 expression from embryonic to adult chickens (1993) (24)
- Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization (1990) (24)
- Sequence of a complete chicken delta-crystallin cDNA. (1984) (23)
- Stromal edema in klf4 conditional null mouse cornea is associated with altered collagen fibril organization and reduced proteoglycans. (2009) (23)
- Gelsolin is a dorsalizing factor in zebrafish (2003) (22)
- Effect of serum on the synthesis of RNA and of DNA in the cultured lens epithelium of the chick embryo: initiation of lens fiber formation in vitro. (1971) (22)
- Isolation and partial characterization of the human αA-crystallin gene* (1986) (21)
- Delta crystallins and their nucleic acids (2004) (21)
- Molecular weight and sequence complexity of δ-crystallin mRNA (1976) (21)
- Phosphorylations of alpha A- and alpha B-crystallin. (1998) (21)
- A complex enhancer of the chicken beta A3/A1-crystallin gene depends on an AP-1-CRE element for activity. (1997) (21)
- Identification of negative-acting and protein-binding elements in the mouse alpha A-crystallin -1556/-1165 region. (1994) (21)
- Protein synthesis by unfertilized eggs of sea urchins. (1968) (21)
- Heterogeneous expression of transketolase in ocular tissues. (1997) (21)
- alpha B-crystallin TATA sequence mutations: lens-preference for the proximal TATA box and the distal TATA-like sequence in transgenic mice. (1997) (21)
- Dual use of the transcriptional repressor (CtBP2)/ribbon synapse (RIBEYE) gene: how prevalent are multifunctional genes? (2001) (20)
- Serum albumin in mammalian cornea: implications for clinical application. (2003) (20)
- BIR-1, a Caenorhabditis elegans homologue of Survivin, regulates transcription and development (2003) (20)
- Evolutionary and developmental differences in delta-crystallin from bird and reptile lenses. Circular dichroism and fluorescence studies. (1980) (20)
- Binding of nuclear proteins to promoter elements of the mouse alpha A-crystallin gene. (1988) (19)
- The mouse transketolase (TKT) gene: cloning, characterization, and functional promoter analysis. (1998) (19)
- Two δ‐crystallin polypeptides are derived from a cloned δ1 ‐crystallin cDNA (1986) (19)
- Heterogeneity of delta-crystallins of the embryonic mallard lens. Correlation between subunit compositions and isoelectric points. (1979) (19)
- Differential expression of the two delta-crystallin/argininosuccinate lyase genes in lens, heart, and brain of chicken embryos. (1990) (18)
- Lens-Specific Promoter Activity ofaMouse-y-Crystallin Gene (1985) (18)
- Developmental changes in proteins of purified membranes of chicken lenses and evidence for contamination by cytoplasmic delta-crystallin. (1979) (18)
- Regulation of the murine alpha A-crystallin promoter in transgenic mice. (1990) (17)
- Translational regulation of delta-crystallin synthesis during lens development in the chicken embryo. (1981) (17)
- Overexpression of PAX 6 ( 5 a ) in lens fiber cells results in cataract and upregulation of α 5 β 1 integrin expression (2000) (17)
- Regulation of Mouse Small Heat Shock Protein αb-Crystallin Gene by Aryl Hydrocarbon Receptor (2011) (17)
- Subunit composition of delta-crystallin from embryonic chick lens. Analysis of methionine-containing tryptic peptides and cyanogen bromide peptides. (1976) (17)
- Initial studies on cultured embryonic chick lens epithelial cells infected with a temperature-sensitive Rous sarcoma virus (1981) (16)
- Structural features of δ-crystallin of turtle lens (1982) (15)
- Anion and cation effects on delta-crystallin synthesis in the cultured embryonic chick lens and in a reticulocyte lysate. (1980) (15)
- Regulation of the mouse alphaB-crystallin and MKBP/HspB2 promoter activities by shared and gene specific intergenic elements: the importance of context dependency. (2007) (14)
- Promoter sequences of murine alpha A crystallin, murine alpha 2(I) collagen or of avian sarcoma virus genes linked to the bacterial chloramphenicol acetyl transferase gene direct tissue-specific patterns of chloramphenicol acetyl transferase expression in transgenic mice. (1985) (14)
- Abundant corneal gelsolin in Zebrafish and the 'four-eyed' fish, Anableps anableps: possible analogy with multifunctional lens crystallins. (2004) (13)
- Radioactive labeling of RNAs of sea urchin eggs during oogenesis. (1967) (12)
- tau-Crystallin from the turtle lens: purification and partial characterization. (1985) (12)
- Direct observation of delta-crystallin accumulation by laser light-scattering spectroscopy in the chicken embryo lens. (1984) (12)
- Differences in isoelectric points and subunit compositions of delta-crystallins synthesized in lenses cultured with and without vitreous bodies. (1978) (12)
- The chicken delta 1-crystallin gene promoter: binding of transcription factor(s) to the upstream G+C-rich region is necessary for promoter function in vitro. (1986) (12)
- Lens and cornea: the "refracton hypothesis". (2008) (12)
- Ribonuclease and trypsin treatment of ribosomes and polyribosomes from sea urchin eggs. (1968) (11)
- Analysis of α-crystallin expression in cultured mouse and rabbit lens cells (1995) (11)
- Structural and functional similarities of delta-crystallin messenger ribonucleic acids from duck and chicken lenses. (1981) (11)
- Linkage and expression of the argininosuccinate lyase/delta-crystallin genes of the duck: insertion of a CR1 element in the intergenic spacer. (1995) (11)
- Two tryptic peptide differences among the subunits of δ-crystallin of the embryonic chick lens (1980) (11)
- Reiteration frequency of delta-crystallin DNA in lens and non-lens tissues of chick embryos. delta-Crystallin gene is not amplified during lens cell differentiation. (1976) (11)
- Lens development and crystallin gene expression : many roles for Pax6 Ale 5 Cvekl and (2004) (10)
- Evidence for positive and negative regulation in the promoter of the chicken delta 1-crystallin gene. (1988) (10)
- Identification of a lens-specific regulatory region (LSR) of the murine alpha B-crystallin gene. (1994) (10)
- Lens Proteins and Their Molecular Biology (2008) (10)
- Cloning and characterization of a novel zinc-finger protein-encoding cDNA from the mouse eye lens. (1993) (10)
- Lens protein gene expression: alpha-crystallins and MIP. (1991) (10)
- The transcription factor, Kid-1, is highly expressed in both eye and kidney of the mouse. (1997) (10)
- Assignment of the mouse alpha A-crystallin structural gene to chromosome 17. (1985) (9)
- Development of the Ocular Lens: Lens Crystallins (2004) (9)
- Confirmation of assignment of the human α1-crystallin gene (CRYA1) to chromosome 21 with regional localization to q22.3 (1987) (9)
- Evolutionary genetics: Seeing the light: the role of inherited developmental cascades in the origins of vertebrate lenses and their crystallins (2006) (9)
- Crystallin genes: lens specificity of the murine alpha A-crystallin gene. (1987) (9)
- Post-translational modification of δ-crystallin in the embryonic chick lens (1975) (9)
- Scallop lens Ω-crystallin (ALDH1A9): A novel tetrameric aldehyde dehydrogenase (2006) (9)
- The nucleic acid and deduced protein sequence of cDNA clones for δ‐crystallin of the chicken lens (1982) (9)
- cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B. (1995) (9)
- A Genetic Perspective on Eye Evolution: Gene Sharing, Convergence and Parallelism (2008) (9)
- Molecular analyses of carbonic anhydrase‐II expression and regulation in the developing chicken lens (1992) (9)
- Differential expression patterns and developmental roles of duplicated scinderin‐like genes in zebrafish (2009) (9)
- Crystallin genes: templates for lens transparency. (1984) (8)
- Molecular biology: Recent studies on enzyme/crystallins and α-crystallin gene expression (1990) (8)
- O-Crystallin, arginine kinase and ferritin from the octopus lens. (1999) (8)
- Promoter activity of the two chicken 5-crystallin genes in a Hela cell extract (1988) (8)
- Conversion from Oligomers to Tetramers Enhances Autophosphorylation by Lens A-Crystallin (1995) (8)
- Binding of tissue-specific forms of alpha A-CRYBP1 to their regulatory sequence in the mouse alpha A-crystallin-encoding gene: double-label immunoblotting of UV-crosslinked complexes. (1993) (8)
- Changes upon fertilization in the distribution of RNA-containing particles in sea urchin eggs. (1970) (8)
- Structure and expression of the duck alpha-enolase/tau-crystallin-encoding gene. (1991) (7)
- delta-crystallin synthesis and vacuole formation during induced opacification of cultured embryonic chick lenses. (1978) (7)
- Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region. (1997) (7)
- Electrophoretic differences between calf and embryonic chick lens α-crystallin polypeptides (1976) (7)
- Molecular biology: recent studies on enzyme/crystallins and alpha-crystallin gene expression. (1990) (7)
- Differential use of the regulatory elements of the alpha B-crystallin enhancer in cultured murine lung (MLg), lens (alpha TN4-1) and muscle (C2C12) cells. (1995) (7)
- The αA-crystallin gene: Conserved features of the 5′-flanking regions in human, mouse, and chicken (1991) (7)
- Functional redundancy of the DE-1 and alpha A-CRYBP1 regulatory sites of the mouse alpha A-crystallin promoter. (1993) (7)
- Evolution of Mollusc Lens Crystallins: Glutathione S-transferase/S-crystallins and Aldehyde Dehydrogenase/Ω-crystallins* (2008) (7)
- Eye-specific expression of an ancestral jellyfish PaxB gene interferes with Pax6 function despite its conserved Pax6/Pax2 characteristics. (2009) (6)
- Lens-preferred activity of chicken delta 1- and delta 2-crystallin enhancers in transgenic mice and evidence for retinoic acid-responsive regulation of the delta 1-crystallin gene. (1997) (6)
- A pseudo-exon in the functional human alpha A-crystallin gene. (1989) (6)
- A mouse cDNA encoding a protein with zinc-fingers and a KRAB domain shows similarity to human profilaggrin. (1994) (5)
- Vertebrate-like βγ-crystallins in the ocular lenses of a copepod (2005) (5)
- Differentiation of lens fiber cells: a brief review of recent developments. (1974) (5)
- Lens-specific activity of the mouse alpha A-crystallin promoter in the absence of a TATA box: functional and protein binding analysis of the mouse alpha A-crystallin PE1 region. (1995) (5)
- delta- and beta-Crystallin mRNA levels in the embryonic and posthatched chicken lens: temporal and spatial changes during development. (1985) (5)
- Expression of the δ1-crystallin gene: salt-dependent alteration in the cell-free synthesis of δ-crystallin polypeptides (1987) (5)
- Histones of chick embryonic lens nuclei. (1974) (5)
- Expression of the delta-crystallin genes in the embryonic chicken lens. (1988) (5)
- Tissue-specific activity of the blind mole rat and the two nucleotide-mutated mouse αB-crystallin promoter in transgenic mice (2007) (5)
- The twelfth Frederick H. Verhoeff Lecture: gene sharing in the visual system. (1993) (4)
- The chicken beta A4- and beta B1-crystallin-encoding genes are tightly linked. (1995) (4)
- Identification of Candidate Klf 4 Target Genes Reveals the Molecular Basis of the Diverse Regulatory Roles of Klf 4 in the Mouse Cornea (2008) (4)
- Displacement of valine from intact sea-urchin eggs by exogenous amino acids. (1968) (4)
- Lens research: More than meets the eye Molecular and Cellular Biology of the Eye Lens. Edited by H. Bloemendal. New York: John Wiley and Sons. (1981). 469 pp. $68.50 (1981) (4)
- Primary structure and lens-specific expression of genes for an intermediate filament protein and a beta-tubulin in cephalopods. (1993) (4)
- Scallop lens Omega-crystallin (ALDH1A9): a novel tetrameric aldehyde dehydrogenase. (2006) (4)
- Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens. (1995) (4)
- Pax-6 and lens-specific transcription of the chicken 81-crystallin gene (2005) (4)
- Analysis of alpha-crystallin expression in cultured mouse and rabbit lens cells. (1995) (4)
- Age-dependent differences in the ratio of synthesis of delta-crystallin polypeptides in cultured vitreous-free lenses of chick embryos. (1979) (3)
- Frederick Bettelheim (1923–2004) (2004) (3)
- [The evolutionary kinship of the crystallins of cephalopods and vertebrates with heat-shock proteins and stress-induced proteins]. (1994) (3)
- Sequence and expression of chicken beta A2- and beta B3-crystallins. (1996) (3)
- Structure and lens expression of the gene encoding chicken beta A3/A1-crystallin. (1992) (3)
- Aldehyde Dehydrogenase-derived O-Crystallins of Squid and Octopus (2001) (3)
- A molecular genetic approach to vision Research: Crystallin gene expression in the lens (1983) (3)
- Multiple y-crystallins of the mouse lens: Fractionation of mRNAs by cDNA cloning (2003) (3)
- Alternative Splicing of & A-Crystallin RNA (3)
- Isolation and partial characterization of the human alpha A-crystallin gene. (1986) (3)
- Functional analysis of chicken vimentin distal promoter regions in cultured lens cells. (1993) (3)
- Murine Transcription Factor A-crystallin Binding Protein I (1995) (2)
- Two delta-crystallin polypeptides are derived from a cloned delta 1-crystallin cDNA. (1986) (2)
- Degradation of delta-crystallin mRNA in the lens fiber cells of the chicken. (1982) (2)
- Evidence against gamma-crystallin DNA or RNA sequences in the chicken. (1984) (2)
- Chicken lens crystallin DNA sequences show at least two delta-crystallin genes. (1980) (2)
- Ω-Crystallin of the Scallop Lens (2000) (2)
- Regulation of αA-crystallin Gene Expression (1999) (2)
- The control of delta-crystallin gene expression during lens cell development: dissociation of cell elongation, cell division, delta-crystallin synthesis, and delta-crystallin mRNA accumulation. (1977) (2)
- Structure and Expression of the Scallop Ω-Crystallin Gene (2002) (2)
- The alpha A-crystallin gene: conserved features of the 5'-flanking regions in human, mouse, and chicken. (1991) (2)
- Cataract Phenotype in Aldh1a1–/–/aldh3a1–/– Double Knockout Mice (2006) (2)
- Pax-6 and eye development in invertebrates (1996) (1)
- LESIONS IN MYELIN FORMING OLIGODENDROCYTES OF TADPOLE OPTIC NERVES: COMPARISON OF CYCLOHEXIMIDE, LOW TEMPERATURE, AND COLCHICINE (1977) (1)
- A novel cDNA isolated from the mouse eye lens encoding a protein with zinc fingers and a KRAB domain. (1995) (1)
- Proctor Award and Lecture. Introduction of Joseph Horwitz for the Proctor Medal. (1993) (1)
- Conservation of mouse αA-crystallin promoter activity in chicken lens epithelial cells (1992) (1)
- Aldh3a1(-/-) Knockout Mice Reveal Novel Functions of Corneal Crystallins (2007) (1)
- Transcriptional Control of the α-Crystallin Gene Family (1991) (1)
- MicroRNA Expression During Mouse Cornea Development (2008) (1)
- Specificity of Gene Expression and Insertional Mutagenesis in Transgenic Mice (1987) (1)
- Molecular biology of the eye : genes, vision, and ocular disease : proceedings of a National Eye Institute-UCLA symposium held at Santa Fe, New Mexico, February 6-12, 1988 (1988) (1)
- Expression of the delta 1-crystallin gene: salt-dependent alteration in the cell-free synthesis of delta-crystallin polypeptides. (1987) (1)
- Differential expression of the two delta-crystallin genes in lens and non-lens tissues: shift favoring delta 2 expression from embryonic to adult chickens. (1993) (1)
- Slurp-1 Promoter Activity Is Regulated by KLF4 in the Corneal Epithelial and Skin Keratinocytes (2008) (1)
- Isolation and in vitro translation of delta-crystallin mRNA from embryonic chick lens fibers. (1974) (1)
- 1. What Is “Gene Sharing”? (2007) (1)
- Conservation of mouse alpha A-crystallin promoter activity in chicken lens epithelial cells. (1992) (1)
- THE TWELFTH (2005) (1)
- Conservation of δ-crystallin gene structure between ducks and chickens (2007) (1)
- ERRATUM: Vertebrate-like βγ-crystallins in the ocular lenses of a copepod (2007) (1)
- Delta-crystallin mRNA in chick lens cells: mRNA accumulates during differential stimulation of delta-crystallin synthesis in cultured cells. (1976) (1)
- ALDH3A1 PROTECTS CORNEA AND LENS AGAINST UVB–INDUCED 4–HNE–PROTEIN ADDUCT FORMATION (2004) (1)
- V-Crystallin of the Scallop Lens (2000) (1)
- Crystallins and Cataractogenesis: A Molecular Genetic Approach (1985) (1)
- Development and Initial Characterization of the Aldh1a1(–/–)/Aldh3a1(–/–) Double Knockout Mice (2005) (1)
- An insulator–like sequence acts as a negative regulatory element in between the mouse Shsp/B–crystallin enhancer and Mkbp/HspB2 promoter. (2004) (1)
- An analysis of zinc finger cDNAs isolated from the newborn mouse lens (1992) (0)
- Complete nucleotide sequence of the chicken alpha A-crystallin gene and its 5' flanking region. (1987) (0)
- Lens-specific promoter activity of a mouse gamma-crystallin gene (1985) (0)
- Mechanistic Insight Into the Diverse Regulatory Roles of Krüppel-Like Transcription Factor KLF4 in the Mouse Cornea (2007) (0)
- ChickenPBI-Crystallin GeneExpression: Presence ofConserved Functional Polyomavirus Enhancer-Like andOctamer Binding-Like Promoter Elements FoundinNon-Lens Genes (1991) (0)
- Official Publication of the Association for Research in Vision and Ophthalmology (1994) (0)
- Recruitment of detoxification enzymes as lens crystallins in cephalopods (1992) (0)
- Ancestry of Photic and Mechanic Sensation? (2005) (0)
- Tetramerization Enhances Autophosphorylation of Lens Alpha-a-Crystallin (1995) (0)
- Dicer and microRNAs Are Essential for Development of Lens and Cornea in Mice (2009) (0)
- Ultrastructural Basis for the Stromal Edema in Klf4CN Mouse Corneas (2008) (0)
- Alzheimer's disease proteins and amyloid in normal and cataractous lenses (1997) (0)
- 6. Gene Sharing as a Common Event: Many Multifunctional Proteins (2007) (0)
- Adaptive Changes of Small Heat Shock Protein/B-Crystallin Promoter Activity of the Blind Mole Rat to Subterranean Life (2002) (0)
- Molecular analysis of mouse αA- and αB-crystallin gene expression in lens and non-lens cells (1992) (0)
- Genomic Analyses and Relative Expression Patterns of the Genes for Cornea/Lens-specific and Ubiquitous Gelsolins in Zebrafish (2002) (0)
- 9. Gene Duplication and the Evolution of New Functions (2007) (0)
- 8. Gene Sharing As a Dynamic Evolutionary Process: Antifreeze Proteins and Hemoglobins (2007) (0)
- Expression of the chicken and duck δ2-crystallin gene (1996) (0)
- Lens Opacification and Corneal Edema in Aldh1a1(-/-), Aldh3a1(-/-) Single and Double Knockout Mice after UVB Exposure (2007) (0)
- 5. The Enigmatic “Corneal Crystallins”: Putative Cases of Gene Sharing (2007) (0)
- Sequence of a complete chicken 6-crystallin cDNA ( lens / translation initiation / mRNA ) (0)
- Author index (1996) (0)
- Electrophoretic differences between calf and embryonic chick lens alpha-crystallin polypeptides. (1976) (0)
- Conversion of B–crystallin Promoter Activity From Mouse to Blind Mole Rat by Site–Specific Mutagenesis (2006) (0)
- Gelsolin Is the Most Abundant Water-soluble Protein in the Corneal Epithelium of Anableps anableps, the Four-eyed Fish (2003) (0)
- Conservation of delta-crystallin gene structure between ducks and chickens. (1987) (0)
- Regulation of carbonic anhydrase II in vitro and in vivo in the developing lens and retina (1992) (0)
- Post-translational modification of delta-crystallin in the embryonic chick lens. (1975) (0)
- Expression oftheMurineoLB-Crystallin GeneinLensandSkeletal Muscle: Identification ofa Muscle-Preferred Enhancer (1991) (0)
- Gene expression in the lens: Tissue-specific regulatory sequences in the 5' flanking region of crystallin genes (1985) (0)
- Differential Expression Patterns and Developmental Roles of Duplicated Scinderin-Like Genes in Zebrafish (2009) (0)
- 4. Eyes and Lenses: Gene Sharing by Crystallins (2007) (0)
- Two tryptic peptide differences among the subunits of delta-crystallin of the embryonic chick lens. (1980) (0)
- 10. Gene Sharing and Systems Biology: Implications and Speculations (2007) (0)
- Regulation of PAX-6 gene expression in the lens (1996) (0)
- Differential Expression of B1 and B2 Crystallin in Zebrafish (2006) (0)
- Comparison of two b-crystallin genes in the chicken ( molecular cloning / chicken lens / gene organization ) (0)
- Involvement of Aldehyde Dehydrogenase 1 in the Oxidation of 4-hydroxynonenal in Rat Lens and Human Lens Epithelial Cells (2003) (0)
- From Science to Writing: A Personal Perspective (2016) (0)
- Regulation of Murine Eye Development by Kruppel–Like Transcription Factor KLF4 (2006) (0)
- 2. Multifunctions and Functional Shifts: Echos from the Past (2007) (0)
- Stromal Edema in Klf 4 Conditional Null Mouse Cornea Is Associated with Altered Collagen Fibril Organization and Reduced (2009) (0)
- Molecular weight and sequence complexity of delta-crystallin mRNA. (1976) (0)
- Regulation of the murine αB-crystallin gene in lens (1996) (0)
- Structural features of delta-crystallin of turtle lens. (1982) (0)
- CLONING AND SEQUENCING OF A cDNA FOR αA CRYSTALLIN mRNA OF THE MOUSE LENS: PRESENCE OF AN EXTENSIVE 3’ UNTRANSLATED REGION (1982) (0)
- Vertebrate-like betagamma-crystallins in the ocular lenses of a copepod. (2005) (0)
- Gene sharing in the lens and cornea as an evolutionary strategy (1999) (0)
- Promoter activity of the two chicken delta-crystallin genes in a Hela cell extract. (1988) (0)
- The Abundant Gelsolin–Like Corneal Protein of Zebrafish Is Adseverin (2006) (0)
- The Aryl Hydrocarbon Receptor Activates the Small Heat Shock Protein/B-Crystallin Promoter in Absence of Exogenous Ligand (2008) (0)
- Krüppel-Like Factor 4 Contributes to Corneal Epithelial and Epidermal Barrier Functions by Upregulating Dsp, Dsg-1a and Dsg-1b Promoter Activities (2009) (0)
- Cornea-preferred Transcription of Rabbit ALDH1A1: Importance of Cis-elements Mediating a Hypoxic Response (2003) (0)
- Role of the αA-Crybp1 Site in Lens-Specific Expression of the αA-Crystallin Gene (1992) (0)
- 3. The Elusive Concept of a “Gene” (2007) (0)
- Two Gelsolin Genes in Zebrafish: Differences in Structure and Expression Pattern (2005) (0)
- Studies on nucleoside and amino acid uptake and on RNA and protein synthesis by growing oocytes, unfertilized and fertilized (1967) (0)
- Differential Expression Patterns and Functions of Duplicated Scinderin-Like Genes During Zebrafish Development (2008) (0)
- Reflections on Basic Science (2010) (0)
- Regulation of the Murine (cid:97) B-Crystallin/Small Heat Shock Protein Gene in Cardiac Muscle (1995) (0)
- Role of Krüppel-Like Factor 4 in Mouse Lens Gene Expression, Development and Function (2010) (0)
- 11. Recapitulations: Ambiguities and Possibilities (2007) (0)
- Quantitation of b-crystallin messenger RNA during lens induction in chick embryos ( embryonic induction / lens crystallins / differentiation ) (0)
- David C. Beebe, 1944-2015, in memoriam. (2017) (0)
- 7. Gene Sharing during Gene Expression (2007) (0)
- Prize awarded to Hans Bloemendal (1985) (0)
- PAX6, a "master gene" for eye development: Target genes and mechanism of action (1996) (0)
- Differential Expression of Gelsolin-Like Genes in Zebrafish: Initial Promoter Analysis of the Corneal Crystallin, Scinla. (2007) (0)
- Orientation-Dependency and Silencing of an Inter-Genic Enhancer in the Divergently Transcribed Mouse B-Crystallin and MKBP/HSPB2 Genes (2002) (0)
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