J. Raymond Klein
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Published Works
- CD43 is a murine T cell costimulatory receptor that functions independently of CD28 (1995) (150)
- Differentiation and functional maturation of bone marrow-derived intestinal epithelial T cells expressing membrane T cell receptor in athymic radiation chimeras. (1990) (145)
- MicroRNA signatures differentiate Crohn’s disease from ulcerative colitis (2015) (141)
- Local Hormone Networks and Intestinal T Cell Homeostasis (1997) (134)
- Cytotoxic T lymphocytes produce immune interferon in response to antigen or mitogen (1982) (116)
- The Immune System as a Regulator of Thyroid Hormone Activity (2006) (109)
- Selective Upregulation of microRNA Expression in Peripheral Blood Leukocytes in IL-10−/− Mice Precedes Expression in the Colon (2011) (99)
- Ontogeny of the Thy-1-, Lyt-2+ murine intestinal intraepithelial lymphocyte. Characterization of a unique population of thymus- independent cytotoxic effector cells in the intestinal mucosa (1986) (97)
- CD4+CD8+ murine intestinal intraepithelial lymphocytes. (1990) (95)
- Antigenic drift in visna: virus variation during long-term infection of Icelandic sheep. (1983) (94)
- Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestine (1992) (93)
- Thymus-neuroendocrine interactions in extrathymic T cell development. (1994) (90)
- The Thyrotropin (Thyroid-Stimulating Hormone) Receptor Is Expressed on Murine Dendritic Cells and on a Subset of CD45RBhigh Lymph Node T Cells: Functional Role for Thyroid-Stimulating Hormone During Immune Activation1 (2000) (83)
- Effect of convulsive activity upon the concentration of brain glucose, glycogen, lactate, and phosphates. (1947) (74)
- A rapid method for isolating murine intestine intraepithelial lymphocytes with high yield and purity. (1992) (74)
- Most Murine CD8+ Intestinal Intraepithelial Lymphocytes Are Partially But Not Fully Activated T Cells1 (2002) (71)
- Distribution of intravenously injected glutamate, lactate, pyruvate, and succinate between blood and brain. (1947) (62)
- T‐cell activation in the intestinal mucosa (2007) (61)
- Multiple Levels of Activation of Murine CD8+ Intraepithelial Lymphocytes Defined by OX40 (CD134) Expression: Effects on Cell-Mediated Cytotoxicity, IFN-γ, and IL-10 Regulation1 (2001) (60)
- An intrinsic thyrotropin-mediated pathway of TNF-α production by bone marrow cells (2003) (58)
- Physiological Relevance of Thyroid Stimulating Hormone and Thyroid Stimulating Hormone Receptor in Tissues other than the Thyroid (2003) (58)
- Proliferative properties of murine intestinal intraepithelial lymphocytes (IEL): IEL expressing TCRαβ or TCRτδ are largely unresponsive to proliferative signals mediated via conventional stimulation of the CD3-TCR complex (1991) (58)
- An improved method for isolating intraepithelial lymphocytes (IELs) from the murine small intestine with consistently high purity. (2006) (57)
- Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine? (1983) (52)
- Bone marrow cells produce a novel TSHβ splice variant that is upregulated in the thyroid following systemic virus infection (2009) (48)
- Monoclonal antibodies specific for a murine cytotoxic T-lymphocyte clone. (1984) (48)
- Antigen-independent activation of memory cytotoxic T cells by interleukin 2. (1984) (46)
- The inactivation of pyridine nucleotides by animal tissues in vitro. (1942) (45)
- Secretion of immune interferon and generation of cytotoxic T cell activity in nude mice are dependent on interleukin 2: age-associated endogenous production of interleukin 2 in nude mice. (1983) (45)
- Isolation and partial characterization of concanavalin A receptors on cloned cytotoxic T lymphocytes. (1984) (43)
- Immune function of thyroid stimulating hormone and receptor. (2001) (42)
- INHIBITION OF THE d-AMINO ACID OXIDASE BY BENZOIC ACID (1941) (42)
- Nonspecific recruitment of cytotoxic effector cells in the intestinal mucosa of antigen-primed mice (1984) (41)
- Formation of heme by broken-cell preparations of duck erythrocytes. (1956) (39)
- Rearrangement and junctional-site sequence analyses of T-cell receptor gamma genes in intestinal intraepithelial lymphocytes from murine athymic chimeras (1991) (37)
- Rapid and transient reduction in circulating thyroid hormones following systemic antigen priming: implications for functional collaboration between dendritic cells and thyroid. (2001) (36)
- Hormonal regulation of extrathymic gut T cell development: involvement of thyroid stimulating hormone. (1995) (36)
- Differential cytokine patterns in mouse macrophages and gingival fibroblasts after stimulation with porphyromonas gingivalis or Escherichia coli lipopolysaccharide. (2010) (34)
- THE OXIDATIVE DEMETHYLATION OF SARCOSINE TO GLYCINE (1941) (33)
- THE ACETYLATION OF SULFANILAMIDE IN VITRO (1938) (33)
- Characterization of a novel set of resident intrathyroidal bone marrow-derived hematopoietic cells: potential for immune-endocrine interactions in thyroid homeostasis (2004) (32)
- Effect of cyanide on the concentration of lactate and phosphates in brain. (1947) (30)
- Inhibition of D-amino acid oxidase by aromatic acids. (1953) (30)
- Blood and Packed Cell Volume of the Adult Rat as Measured by Tagged Cells.∗ (1950) (30)
- Porphyromonas gingivalis lipopolysaccharide induces tumor necrosis factor-alpha and interleukin-6 secretion, and CCL25 gene expression, in mouse primary gingival cell lines: interleukin-6-driven activation of CCL2. (2008) (30)
- Neuroendocrine-induced synthesis of bone marrow-derived cytokines with inflammatory immunomodulating properties. (1999) (29)
- Chemokine changes during oral wound healing. (2004) (29)
- Whence the intestinal intraepithelial lymphocyte? (1996) (27)
- Advances in intestinal T-cell development and function. (1995) (27)
- Estimation of blood in tissue. (1945) (27)
- Release of discrete interferons by cytotoxic T lymphocytes in response to immune and nonimmune stimuli. (1984) (27)
- Effect of carbon dioxide on brain glucose, lactate, pyruvate and phosphates. (1949) (26)
- ICOS promotes IL‐17 synthesis in colonic intraepithelial lymphocytes in IL‐10−/− mice (2010) (26)
- Distribution of intravenously injected fructose and glucose between blood and brain. (1946) (26)
- Intestinal TSH production is localized in crypt enterocytes and in villus 'hotblocks' and is coupled to IL-7 production: evidence for involvement of TSH during acute enteric virus infection. (2005) (25)
- THE SYNTHESIS OF FLAVIN-ADENINE DINUCLEOTIDE FROM RIBOFLAVIN BY HUMAN BLOOD CELLS IN VITRO AND IN VIVO (1940) (25)
- A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid. (2009) (24)
- T cell precursors in the spleen give rise to complex T cell repertoires in the thymus and the intestine. (1995) (24)
- Repopulation kinetics of intestinal intraepithelial lymphocytes in murine bone marrow radiation chimeras. (1992) (24)
- Hormone regulation of murine T cells: potent tissue-specific immunosuppressive effects of thyroxine targeted to gut T cells. (1996) (23)
- Immunological regulation of metabolism—a novel quintessential role for the immune system in health and disease (2011) (23)
- A murine cytotoxic T lymphocyte clone from the intestinal mucosa that is antigen specific for proliferation and displays broadly reactive inducible cytotoxic activity. (1985) (21)
- Precipitating antibodies in experimental visna and natural progressive pneumonia of sheep. (1985) (21)
- SPECIFICITY OF THE d-AMINO ACID OXIDASE (1941) (20)
- The V-factor content and oxygen consumption of tissues of the normal and blacktongue dog. (1939) (20)
- Abrogation of genetically controlled resistance of mice to Treponema pallidum by irradiation (1980) (19)
- T cell progenitors in the murine small intestine. (1997) (19)
- CD43 potentiates CD3‐induced proliferation of murine intestinal intraepithelial lymphocytes (2001) (19)
- Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice (2013) (19)
- A defect in the synthesis of Interferon-γ by the T cells of Complement-C5 deficient mice leads to enhanced susceptibility for tuberculosis. (2011) (18)
- EFFECT OF THYROID FEEDING AND THYROIDECTOMY ON THE OXIDATION OF AMINO ACIDS BY RAT KIDNEY AND LIVER (1939) (17)
- EFFECT OF DIPHOSPHOPYRIDINE NUCLEOTIDE ON THE RATE OF OXIDATION OF BETAINE ALDEHYDE (1942) (17)
- Spontaneous in vitro evolution of lytic specificity of cytotoxic T lymphocyte clones isolated from murine intestinal epithelium. (1987) (17)
- Dynamic regulation of gastric autoimmunity by thyroid hormone. (1998) (17)
- Massive but selective cytokine dysregulation in the colon of IL-10-/- mice revealed by multiplex analysis. (2008) (16)
- Immune-endocrine interactions of the hypothalamus-pituitary-thyroid axis: integration, communication and homeostasis. (2001) (16)
- Antigen-induced chemokine activation in mouse buccal epithelium. (2003) (16)
- An intrinsic thyrotropin-mediated pathway of TNF-alpha production by bone marrow cells. (2003) (15)
- The effect of the level of protein intake upon the urinary excretion of riboflavin and nicotinic acid in dogs and rats. (1942) (15)
- Differential expression of CD43 isoforms on murine T cells and their relationship to acute intestinal graft versus host disease: studies using enhanced-green fluorescent protein transgenic mice. (1999) (15)
- Biological Impact of the TSHβ Splice Variant in Health and Disease (2014) (15)
- Effect of insulin hypoglycemia on brain glucose, glycogen, lactate and phosphates. (1947) (15)
- Activation requirements for antigen- and mitogen-induced interferon-gamma release from cytotoxic T lymphocytes. (1985) (14)
- DETERMINATION OF NICOTINIC ACID IN BLOOD CELLS AND PLASMA (1942) (14)
- Cerebrospinal fluid immunoglobulins in sheep with visna, a slow virus infection of the central nervous system (1982) (14)
- Selective upregulation of immune regulatory and effector cytokine synthesis by intestinal intraepithelial lymphocytes following CD43 costimulation. (2005) (14)
- Immune Activation for Thyroid-Stimulating Hormone During Lymph Node T Cells : Functional Rolehigh Dendritic Cells and on a Subset of CD 45 RB Hormone ) Receptor Is Expressed on Murine The Thyrotropin ( Thyroid-Stimulating (2000) (13)
- Hormone regulation of immune homeostasis: local or long distance? (1998) (13)
- Phenotype and TCR-γδ variable gene repertoire of intestinal intraepithelial lymphocytes in wild mice (mus musculus domesticus): Abundance of Vγ1 transcripts and extensive δ gene diversity (1994) (13)
- NATURE OF THE INCREASE IN ACTIVITY OF THE d-AMINO ACID OXIDASE OF RAT LIVER PRODUCED BY THYROID FEEDING (1939) (13)
- Acetylation of Sulfanilamide by Liver Tissue in vitro. (1938) (12)
- Thymus-independent development of gut T cells. (1998) (12)
- Hyperglycemia Induced by Certain Insulin Preparations.∗ (1947) (12)
- Characterization of novel anti-mouse thyrotropin monoclonal antibodies. (2002) (12)
- Roquin – a multifunctional regulator of immune homeostasis (2015) (12)
- Maximum Immunobioactivity of Murine Small Intestinal Intraepithelial Lymphocytes Resides in a Subpopulation of CD43+ T Cells1 (2004) (11)
- Primary demyelination in visna (1982) (11)
- A novel marker of murine bone marrow hematopoietic stem cells that is expressed on peripheral T cells and is associated with a functionally important molecule on activated cytotoxic T lymphocytes. (1994) (11)
- Stimulation via the CD43 coreceptor augments T cell proliferation during the early phase of antigen-induced activation. (1996) (11)
- Competitive inhibition of D-amino acid oxidase by benzoate as a function of substrate. (1960) (11)
- Upregulation of ICOS on CD43+ CD4+ murine small intestinal intraepithelial lymphocytes during acute reovirus infection. (2006) (11)
- Phenotypic and functional heterogeneity of murine intestinal intraepithelial lymphocytes defined by cell density: implications for route of differentiation and responsiveness to proliferation induction. (1994) (11)
- THE OXIDATION IN VITRO OF N-METHYLAMINO ACIDS BY KIDNEY AND LIVER (1941) (10)
- T cell receptor delta gene repertoire and diversity of intestinal intraepithelial lymphocytes in athymic mice. (1993) (9)
- The synthesis of cozymase and of factor V from nicotmk acid by the human erythrocyte in vitro and in vivo. (1939) (9)
- Splenic Leukocytes Traffic to the Thyroid and Produce a Novel TSHβ Isoform during Acute Listeria monocytogenes Infection in Mice (2016) (9)
- T-cell activation in the curious world of the intestinal intraepithelial lymphocyte (2004) (9)
- Uptake by duck erythrocytes of iron added to blood. (1952) (9)
- A role for IL-10 in the transcriptional regulation of Roquin-1. (2014) (9)
- Novel Splicing of Immune System Thyroid Stimulating Hormone β-Subunit—Genetic Regulation and Biological Importance (2019) (8)
- Net Synthesis of Heme from Protoporphyrin and Iron by Extracts of Duck Erythrocytes.∗ (1959) (8)
- Heat-stable antigen may be an early marker of extrathymic murine intestinal intraepithelial lymphocytes. (1994) (8)
- INHIBITORY EFFECT OF KOJIC ACID UPON OXIDATIONS MEDIATED BY LIVER AND KIDNEY (1947) (8)
- Origins of intestinal intraepithelial lymphocytes: direct evidence for a thymus-derived γδ T cell component (2000) (7)
- Dynamic Interactions Between the Immune System and the Neuroendocrine System in Health and Disease (2021) (7)
- Origins of intestinal intraepithelial lymphocytes: direct evidence for a thymus-derived gamma delta T cell component. (2000) (7)
- T-lymphopoietic capacity of the mouse intestinal epithelium. (1995) (7)
- γδ T cells, antigen recognition and intestinal immunity (1995) (6)
- Proliferative properties of murine intestinal intraepithelial lymphocytes (IEL): IEL expressing TCR alpha beta or TCR tau delta are largely unresponsive to proliferative signals mediated via conventional stimulation of the CD3-TCR complex. (1991) (6)
- Synthesis of factor V (pyridine nucleotides) from nicotinic acid in vitro by human erytbrocytes. (1940) (6)
- Stimulatory and costimulatory effects of IL‐18 directed to different small intestinal CD43 T cell subsets (2007) (6)
- Functional heterogeneity of murine intestinal intraepithelial lymphocytes: studies using TCR-αβ+ IEL lines and fresh iel isolates reveal multiple cytotoxic subsets differentiated by CD5, CD8α/α, and CD8α/β expression (1994) (6)
- Modulation of γδ T cells in mouse buccal epithelium following antigen priming (2002) (6)
- THE OXIDATION OF l(-)-ASPARTIC AND l(+)-GLUTAMIC ACIDS BY HEMOPHILUS PARAINFLUENZAE NOTE ON THE PREPARATION OF PYRIDINE NUCLEOTIDES FROM BAKERS' YEAST BY THE METHOD OF WARBURG AND CHRISTIAN (1940) (6)
- Canine Epilepsy Caused by Flour Bleached with Nitrogen Trichloride (Agene). II. Role of Amino Acids.∗ (1947) (6)
- Extrathymic development of alpha beta TCR-bearing IEL. (1992) (5)
- Hematopoietic not systemic impairment of Roquin expression accounts for intestinal inflammation in Roquin-deficient mice (2014) (5)
- Soluble gp130 promotes intestinal epithelial hyperplasia during reovirus infection (2010) (5)
- Virus infection activates thyroid stimulating hormone synthesis in intestinal epithelial cells (2008) (5)
- Immune recognition by cytotoxic T lymphocytes of minor histocompatibility antigens expressed on a murine colon carcinoma line. (1989) (5)
- Effect of competitive inhibitors on the inactivation of D-amino acid oxidase and its protein component by oxygen. (1957) (4)
- In vitro antigen-specific response of spleen cells from Treponema pallidum-infected mice. (1980) (4)
- Oxidation of fructose by brain in vitro. (1944) (4)
- CD 43 Is a Murine T Cell Costimulatory Receptor that Functions Independently of CD 28 By (2003) (4)
- Modulation of gamma delta T cells in mouse buccal epithelium following antigen priming. (2002) (4)
- Incorporation of Manganese into Duck Erythrocytes.∗ (1961) (4)
- Protoporphyrin and heme formation by erythrocytes from the x-irradiated and bled duck. (1961) (4)
- Metabolism of iron in the duck. (1959) (4)
- ACTION OF SODIUM SELENITE ON THE OXIDATION OF l-PROLINE (1941) (4)
- Expression of the Asialo GM1 Determinant on Murine Intestinal Epithelia (1990) (4)
- T cell development within the intestinal mucosa: clues to a novel immune-endocrine network? (1996) (3)
- Erratum to “A novel thyroid stimulating hormone β-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid” [Gen. Comp. Endocrinol. 162 (2009) 241–244] (2009) (3)
- Distribution of free protoporphyrin within duck blood incubated with glycine-2-14C☆☆☆ (1967) (3)
- INHIBITION OF BRAIN RESPIRATION BY PICROTOXIN (1943) (3)
- Experimental intestinal reovirus infection of mice (2006) (2)
- Hemoglobin Heterogeneity in the Pekin Duck 1 (1970) (2)
- Experimental Intestinal Reovirus Infection of Mice: What We Know, What We Need to Know (2009) (2)
- Activation and Costimulation of Intestinal T Cells: Independent and Collaborative Involvement of CD43, OX40, and Ly-6C. (2005) (2)
- Delayed-type hypersensitivity response in mice to Treponema pallidum. (1983) (2)
- Depression of heme formation and production of free porphyrin in duck erythrocytes. (1962) (2)
- Heme and globin synthesis and related parameters in blood from the x-irradiated duck. (1969) (2)
- Effect of Whole-Body X-Irradiation on Uptake of Iron by Duck Erythrocytes.∗ (1955) (2)
- Hyperglycemia following intravenous injection of insulin preparations. (1947) (1)
- Porphyromonas gingivalis lipopolysaccharide induces tumor necrosis factor- α and interleukin-6 (IL-6) secretion and CCL25 gene expression in mouse primary gingival cell lines: IL-6-driven activation of CCL2 (2008) (1)
- Functional heterogeneity of murine intestinal intraepithelial lymphocytes: studies using TCR-alpha beta+ IEL lines and fresh IEL isolates reveal multiple cytotoxic subsets differentiated by CD5, CD8 alpha/alpha, and CD8 alpha/beta expression. (1994) (1)
- Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice. (2017) (1)
- THE OXIDATION OF I(-)-ASPARTIC AND Z(+)-GLUTAMIC ACIDS BY HEMOPHILUS PARAINFLUENZAE (2003) (1)
- Gamma delta T cells, antigen recognition and intestinal immunity. (1995) (1)
- Free Porphyrin Concentrations and Porphyrin Synthesis in Duck Tissues∗ (1968) (1)
- Incorporation of glycine-2-14C into the free protoporphyrin of duck erythrocytes in vivo. (1968) (1)
- Lamina propria lymphocytes in sanroque mice produce proinflammatory cytokines that drive chronic small intestinal inflammation (2017) (1)
- Thyroid stimulating hormone β-subunit splice variant is expressed in all fractional subsets of bone marrow hematopoietic cells and peripheral blood leukocytes and is modulated during bacterial infection. (2020) (1)
- Decrease in uptake of iron by duck erythrocytes in vitro following whole-body x-irradiation. (1955) (1)
- Phenotype and TCR gamma delta variable gene repertoire of intestinal intraepithelial lymphocytes in wild mice (Mus musculus domesticus): abundance of V gamma 1 transcripts and extensive delta gene diversity. (1994) (0)
- T Cells + Resides in a Subpopulation of CD43 Small Intestinal Intraepithelial Lymphocytes Maximum Immunobioactivity of Murine (2004) (0)
- Extrathymic development of αβ TCR-bearing IEL [2] (1992) (0)
- Preparation of radioactive iron from tissue for assay of activity. (1955) (0)
- Natural Effector Cells of the Intestinal Epithelium: Ontogeny, Function, and Regulation (1988) (0)
- Book Review:Mineral Metabolism. An Advanced Treatise. Volume 2, Part A, The Elements. C. L. Comar, Felix Bronner (1964) (0)
- Distribution in the duck of intraperitoneally administered radioiron in erythrocytes, muscle, cytochrome C of muscle, and plasma (1949) (0)
- Effect of carbon dioxide concentration on the changes in brain metabolites accompanying convulsions. (1948) (0)
- Monoclonal antibodies specific for a murine cytotoxic T-lymphocyte clone ( antigen receptor / interferon / immunoprecipitation ) (2003) (0)
- A mechanistic base for alternative splicing of human immune system-derived thyroid stimulating hormone (TSH) β-subunit. (2018) (0)
- Regulatory effects of immune system thyroid stimulating hormone β-subunit splice variant (TSHβv) on thyroid hormone secretion in mice. (2018) (0)
- Lymphoid-epithelial paracrine hormone interactions as regulators of small intestine intraepithelial lymphocyte (l) development and function (1996) (0)
- Book Review:Mammalian Protein Metabolism. Volume IV. H. N. Munro (1971) (0)
- Hormones and intestinal immunity (1998) (0)
- Inhibition of d-amino acid oxidase by kojic acid. (1947) (0)
- Massive colonic cytokine dysregulation in IL-10−/− mice revealed by multiplex analysis (96.17) (2007) (0)
- Crispr/Cas9 Gene Editing Targeted to an Intron of a Novel Isoform of the β-Subunit of Thyroid Stimulating Hormone in Peripheral Leukocytes (2019) (0)
- Splenic monocytes traffic to the thyroid and produce a novel TSHβ splice variant during acute Listeria infection in mice (INC4P.334) (2015) (0)
- Distribution of intravenously injected fructose and glucose between blood and brain. (1946) (0)
- Escape from immune surveillance during persistent virus infection. (1983) (0)
- Effects of x-irradiation on hemoglobin polymorphism in the adult Pekin duck. (1971) (0)
- Book Review:Histocompatibility. George D. Snell, Jean Dausset, Stanley Nathenson (1977) (0)
- 'Self' tolerance in a parent-->F1 radiation chimera. (1999) (0)
- Book Review:Mammalian Protein Metabolism. Vols. I & II. H. N. Munro, J. B. Allison (1965) (0)
- Isotopic Tracers in Biochemistry and Physiology, Jacob Sacks. McGraw-Hill Book Company, Inc., New Haven Conn. (1953), vii + 383 pp. Price $8.50 (1953) (0)
- Incorporation of radioiron into cytochrome C (1949) (0)
- Changes of Noble-Metal Electrode EMF of Cerebral Cortex (1945) (0)
- Blood Volume of the Rat Measured by the Tagged-Erythrocyte Dilution Method (1950) (0)
- Effect of carbon dioxide concentration on brain lactate. (1948) (0)
- Methemoglobinemia Induced by X-Irradiation.∗ (1956) (0)
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