Joseph S. Handler

Joseph S. Handler's AcademicInfluence.com Rankings

Joseph S. Handler

Biology

#12135

World Rank

#15590

Historical Rank

Molecular Biology

#1938

World Rank

#1969

Historical Rank

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Biology

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Joseph S. Handler's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. (1999) (548)
The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder. (1962) (447)
Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity. (1992) (369)
Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane? (1981) (340)
The role of adenosine 3',5'-phosphate in the action of antidiuretic hormone. (1967) (328)
Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein. (1992) (323)
Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(-)-dependent taurine transporter that is regulated by hypertonicity. (1992) (273)
Effect of Prostaglandin (PGEI) on the Permeability Response of Toad Bladder to Vasopressin, Theophylline and Adenosine 3′,5′-monophosphate (1965) (247)
The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress. (1994) (203)
Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia. (1989) (188)
The effect of vasopressin and of theophylline on the concentration of adenosine 3',5'-phosphate in the urinary bladder of the toad. (1965) (177)
Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region* (1998) (173)
Cell volume regulated transporters of compatible osmolytes. (1995) (156)
Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity. (1998) (153)
Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(-)-dependent taurine transporter that is regulated by hypertonicity. (1993) (152)
Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity. (2000) (146)
Transport properties of toad kidney epithelia in culture. (1981) (136)
Molecular cloning of cDNA coding for kidney aldose reductase. Regulation of specific mRNA accumulation by NaCl-mediated osmotic stress. (1989) (135)
Studies of renal cell function using cell culture techniques. (1980) (126)
Medium tonicity regulates expression of the Na(+)- and Cl(-)-dependent betaine transporter in Madin-Darby canine kidney cells by increasing transcription of the transporter gene. (1993) (122)
Vasopressin-stimulated prostaglandin E biosynthesis in the toad urinary bladder. Effect of water flow. (1977) (115)
Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP. (2001) (114)
Toad urinary bladder epithelial cells in culture: maintenance of epithelial structure, sodium transport, and response to hormones. (1979) (112)
Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. Protection by polarized, regulated transport of taurine. (1991) (108)
Hypertonicity stimulates transcription of gene for Na(+)-myo-inositol cotransporter in MDCK cells. (1993) (107)
Effect of adrenergic agents on toad bladder response to ADH, 3',5'-AMP, and theophylline. (1968) (92)
Hyponatremia and renal wasting of sodium in patients with malfunction of the central nervous system. (1960) (92)
Use of cultured epithelia to study transport and its regulation. (1983) (89)
Effect of ADH, aldosterone, ouabain, and amiloride on toad bladder epithelial cells. (1972) (88)
THE CELLULAR MODE OF ACTION OF ANTIDIURETIC HORMONE. (1964) (85)
Isolation, growth, and characterization of a gluconeogenic strain of renal cells. (1987) (85)
Effects of ADH and other agents on cyclic AMP accumulation in toad bladder epithelium. (1974) (85)
Effect of adrenal steroid hormones on the response of the toad's urinary bladder to vasopressin. (1969) (84)
Myo-inositol and betaine transporters regulated by tonicity are basolateral in MDCK cells. (1991) (83)
Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus Oocytes (2004) (82)
Regulation of renal cell organic osmolyte transport by tonicity. (1993) (82)
Complete response to vasopressin requires epithelial organization in A6 cells in culture. (1986) (77)
Hydration status affects nuclear distribution of transcription factor tonicity responsive enhancer binding protein in rat kidney. (2001) (75)
Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump. (1990) (74)
Effect of hypertonicity on permeability properties of the toad bladder. (1970) (74)
Factors affecting the differentiation of epithelial transport and responsiveness to hormones. (1984) (74)
Regulation of sodium-coupled glucose transport by glucose in a cultured epithelium. (1983) (71)
The MAP kinase cascade is not essential for transcriptional stimulation of osmolyte transporter genes. (1995) (70)
Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity. (2002) (70)
Na+-dependent hexose transport in vesicles from cultured renal epithelial cell line. (1982) (69)
Functional Characterization of the Betaine/γ-Aminobutyric Acid Transporter BGT-1 Expressed in Xenopus Oocytes* (1999) (69)
THE EFFECT OF ADRENAL STEROID HORMONES ON EPITHELIA FORMED IN CULTURE BY A6 CELLS (1981) (68)
The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy. (1960) (68)
Antidiuretic hormone. (1981) (68)
Porous-bottom dishes for culture of polarized cells. (1986) (66)
Overview of epithelial polarity. (1989) (64)
The canine betaine gamma-amino-n-butyric acid transporter gene: diverse mRNA isoforms are regulated by hypertonicity and are expressed in a tissue-specific manner. (1995) (63)
Antidiuretic hormone moves membranes. (1988) (63)
Activators of protein kinase C inhibit sodium transport in A6 epithelia. (1986) (61)
Transcriptional regulation by changes in tonicity. (2001) (61)
Gangliosides do not move from apical to basolateral plasma membrane in cultured epithelial cells. (1985) (60)
Vasopressin-like effects of adenosine 3′,5′,-phosphate (cyclic 3′,5′-AMP) and theophylline in the toad bladder (1961) (55)
Adenosine-sensitive phosphoinositide turnover in a newly established renal cell line. (1989) (53)
Identification of the second tonicity-responsive enhancer for the betaine transporter (BGT1) gene. (1999) (51)
Inhibition of vasopressin-stimulated prostaglandin E biosynthesis by chlorpropamide in the toad urinary bladder. Mechanism of enhancement of vasopressin-stimulated water flow. (1977) (50)
Nuclear redistribution of tonicity-responsive enhancer binding protein requires proteasome activity. (2000) (50)
Transepithelial water flow regulates apical membrane retrieval in antidiuretic hormone-stimulated toad urinary bladder. (1986) (49)
Relation between toad bladder potassium content and permeability response to vasopressin. (1966) (47)
Effect of PGE1, indomethacin, and polyphloretin phosphate on toad bladder response to ADH. (1974) (47)
Active chloride transport in the isolated toad bladder. (1967) (47)
Aldosterone and corticosterone binding and effects on Na+ transport in cultured kidney cells. (1982) (46)
Cell and Molecular Biology of Organic Osmolyte Accumulation in Hypertonic Renal Cells (2001) (42)
Vasopressin-prostaglandin interactions in the regulation of epithelial cell permeability to water. (1981) (42)
Expression of Madin-Darby canine kidney cell Na(+)-and Cl(-)-dependent taurine transporter in Xenopus laevis oocytes. (1991) (42)
The effect of aldosterone on the accumulation of adenosine 3':5'-cyclic monophosphate in toad bladder epithelial cells in response to vasopressin and theophylline. (1972) (41)
Adenosine stimulates sodium transport in kidney A6 epithelia in culture. (1985) (40)
EFFECT OF PROSTAGLANDIN (PGE-1) ON THE PERMEABILITY RESPONSE OF TOAD BLADDER TO VASOPRESSIN, THEOPHYLLINE AND ADENOSINE 3',5'-MONOPHOSPHATE. (1965) (40)
Regulation of the myo-inositol and betaine cotransporters by tonicity. (1996) (39)
The effect of aldosterone of glycolysis in the urinary bladder of the toad. (1969) (39)
Ca++ and Mg++ effects on toad bladder response to cyclic AMP, theophylline, and ADH analogues. (1967) (39)
Activators of protein kinase A and of protein kinase C inhibit MDCK cell myo-inositol and betaine uptake. (1995) (39)
Effect of adrenal steroids on vasopressin-stimulated PGE synthesis and water flow. (1978) (38)
Fluorescent membrane probes and the mechanism of maintenance of cellular asymmetry in epithelia. (1982) (38)
Renal Na-myo-inositol cotransporter mRNA expression in Xenopus oocytes: regulation by hypertonicity. (1991) (38)
Apical membrane endocytosis via coated pits is stimulated by removal of antidiuretic hormone from isolated, perfused rabbit cortical collecting tubule (1988) (37)
Adenosine 3',5'-cyclic monophosphate stimulates chloride secretion in A6 epithelia. (1986) (35)
Gangliosides modulate sodium transport in cultured toad kidney epithelia. (1986) (33)
Hormone effects on transport in cultured epithelia with high electrical resistance. (1981) (32)
Fluorescent markers to study membrane retrieval in antidiuretic hormone-treated toad urinary bladder. (1986) (32)
ACTIVATION OF PHOSPHORYLASE IN TOAD BLADDER AND MAMMALIAN KIDNEY BY ANTIDIURETIC HORMONE. (1963) (31)
The effect of aldosterone on cyclic nucleotide phosphodiesterase activity in toad urinary bladder (1973) (29)
Role of calcium in organic osmolyte efflux when MDCK cells are shifted from hypertonic to isotonic medium. (1993) (29)
Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity. (1998) (28)
Effect of extracellular pH on the myo-inositol transporter SMIT expressed in Xenopus oocytes (1998) (28)
Osmolarity in renal medulla of transgenic mice regulates transcription via 5'-flanking region of canine BGT1 gene. (1997) (28)
A study of renal phosphate excretion in the dog. (1962) (28)
Effect of metabolic inhibitors on the response of the toad bladder to vasopressin. (1966) (26)
Effect of inhibitors of sodium transport on response of toad bladder to ADH and cyclic AMP. (1970) (26)
Insulin and serum increase the number of receptors for vasopressin in a kidney-derived line of cells grown in a defined medium. (1980) (26)
Kidney cell survival in high tonicity. (1997) (25)
Dexamethasone accelerates differentiation of A6 epithelia and increases response to vasopressin. (1988) (24)
Cultures as epithelial models: porous-bottom culture dishes for studying transport and differentiation. (1989) (23)
Tyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells. (1999) (23)
Identification of specific apical membrane polypeptides associated with the antidiuretic hormone-elicited water permeability increase in the toad urinary bladder. (1988) (23)
Epithelial organization and hormone sensitivity of toad urinary bladder cells in culture. (1981) (21)
Effect of amphotericin B on permeability and short-circuit current in toad bladder. (1967) (21)
Control of glycogenolysis in the toad's urinary bladder. The effect of anaerobiosis, sodium transport, and arginine vasotocin. (1968) (20)
CYSTEINE EFFECT ON TOAD BLADDER RESPONSE TO VASOPRESSIN, CYCLIC AMP, AND THEOPHYLLINE. (1964) (20)
Sodium- and chloride-dependent transporters in brain, kidney, and gut: lessons from complementary DNA cloning and structure-function studies. (1993) (19)
Monoclonal antibodies as probes of epithelial membrane polarization (1985) (18)
Apical membrane vesicles of ADH-stimulated toad bladder are highly water permeable. (1990) (16)
The canine sodium/myo-inositol cotransporter gene: structural organization and characterization of the promoter. (1997) (16)
Induction of glycinebetaine uptake into Xenopus oocytes by injection of poly(A)+ RNA from renal cells exposed to high extracellular NaCl. (1991) (15)
FACTORS INVOLVED IN THE ACTION OF CYCLIC AMP, ON THE PERMEABILITY OF MAMMALIAN KIDNEY AND TOAD URINARY BLADDER (1971) (14)
Inhibition of toad urinary bladder sodium transport by carbamylcholine: possible role of cyclic GMP. (1978) (13)
A hypothesis for the molecular mechanism of action of chlorpropamide in the treatment of diabetes mellitus and diabetes insipidus. (1977) (12)
Effect of parathyroid hormone and cyclic AMP on protein phosphorylation in rabbit kidney cortex. (1976) (11)
Asymmetry in epithelial cells: is the tight junction a barrier to lateral diffusion in the plasma membrane? (1982) (11)
Release of cyclic AMP by toad urinary bladder. (1975) (11)
Study of enzymes regulating vasopressin-stimulated cyclic AMP metabolism in separated mitochondria-rich and granular epithelial cells of toad urinary bladder (1976) (9)
Effect of aldosterone on the sodium content and energy metabolism of epithelial cells of the toad urinary bladder. (1972) (9)
Hexose regulation of sodium-hexose transport in LLC-PK1 epithelia: The nature of the signal (2005) (9)
The role of membrane turnover in the water permeability response to antidiuretic hormone (1988) (8)
Isolation and characterization of specialized regions of toad urinary bladder apical plasma membrane involved in the water permeability response to antidiuretic hormone (2005) (8)
Refractoriness of toad bladder to stimulation of sodium transport. (1972) (8)
A device for sterile measurement of transepithelial electrical parameters of cultured cells (1992) (7)
Transport in cultured epithelia. (1985) (7)
Role of cell replication in regulation of Na-coupled hexose transport in LLC-PK1 epithelial cells. (1986) (7)
Vasopressin-elicited refractoriness of the response to vasopressin in toad urinary bladder. (1981) (6)
Effect of sodium transport and vasopression on the oxidation of palmitic acid by the toad bladder. (1968) (5)
Precursors of ribose 5-phosphate suppress expression of glucose-regulated proteins in LLC-PK1 cells. (1987) (5)
Central levodopa metabolism in Parkinson's disease after administration of stable isotope—labeled levodopa (1997) (5)
Effect of aldosterone on cyclic-AMP metabolism in the urinary bladder of the toad. (1973) (4)
Kidney-derived cells show multidrug secretory transport. (1991) (3)
The effect of some nucleotides and related compounds on sodium transport and water permeability of the urinary bladder of the toad. (1973) (3)
Evoked Potential Testing in Clinical Neurotoxicology (1995) (3)
Regulation of transport in cultured epithelia (1985) (3)
Regulation of expression of the sodium-coupled hexose transporter in cultured LLC-PK1 epithelia (2004) (2)
Neurohypophysial peptide potencies in cultured anuran epithelia (A6). (1986) (2)
The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder. 1962. (1999) (1)
Title Page / III International Congress of Nephrology / Scheduled under the general sponsorship of the International Society of Nephrology / Officers of Previous Congresses / Preface / Index (1967) (0)
CELLULAR MODE OF ACTION OF ANTIDIURETIC HORMONE. (1965) (0)
Protection by Polarized, Regulated Transport of Taurine (2014) (0)
Monoclonai Polarization Antibodies As Probes of Epithelial Membrane (2002) (0)
Determinants of Growth, Form, and Function in Epithelia (1984) (0)
Application of Tissue Culture Techniques to Study of Renal Tubular Epithelia (2011) (0)
The canine betaine y-amino-n-butyric acid transporter gene: Diverse mRNA isoforms are regulated by hypertonicity and are expressed in a tissue-specific manner (2005) (0)

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Joseph S. Handler's Published Works

Published Works

What Schools Are Affiliated With Joseph S. Handler?

Joseph S. Handler's AcademicInfluence.com Rankings