Jerold S. Harmatz
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Medical Philosophy
Jerold S. Harmatz's Degrees
- PhD Pharmacology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
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(Suggest an Edit or Addition)Jerold S. Harmatz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Diazepam disposition determinants (1980) (363)
- Dose‐Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans (1997) (333)
- A New Scale for Clinical Assessment in Geriatric Populations: Sandoz Clinical Assessment – Geriatric (SCAG) * (1974) (306)
- Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir (1998) (267)
- A double-blind placebo controlled study of desipramine in the treatment of ADD: I. Efficacy. (1989) (266)
- Sensitivity to triazolam in the elderly. (1991) (241)
- Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole. (1996) (241)
- Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents (1996) (229)
- Oxazepam kinetics: effects of age and sex. (1980) (214)
- Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram. (2001) (205)
- In vitro approaches to predicting drug interactions in vivo. (1998) (205)
- Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches. (2000) (196)
- Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice (2003) (186)
- Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. (1995) (183)
- Benzodiazepines: a summary of pharmacokinetic properties. (1981) (174)
- Effect of age and gender on disposition of temazepam. (1981) (170)
- Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo. (1994) (168)
- Clinical Pharmacokinetics of Anxiolytics and Hypnotics in the Elderly (1991) (167)
- Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine. (1994) (166)
- O- and N-demethylation of Venlafaxine In Vitro by Human Liver Microsomes and by Microsomes from cDNA-Transfected Cells: Effect of Metabolic Inhibitors and SSRI Antidepressants (1999) (162)
- Drug interactions with newer antidepressants: role of human cytochromes P450. (1998) (160)
- Clinical Pharmacokinetics of Anxiolytics and Hypnotics in the Elderly (2012) (160)
- Five Distinct Human Cytochromes Mediate Amitriptyline N‐Demethylation In Vitro: Dominance of CYP 2C19 and 3A4 (1998) (154)
- Pharmacokinetics and Bioavailability of Intravenous, Intramuscular, and Oral Lorazepam in Humans (1979) (152)
- Variability of 24‐Hour Urinary Creatinine Excretion by Normal Subjects (1976) (152)
- Amitriptyline in the Treatment of Anorexia Nervosa: A Double‐Blind, Placebo‐Controlled Study (1985) (151)
- Lorazepam kinetics in the elderly (1979) (150)
- Inhibition of human cytochromes P450 by components of Ginkgo biloba (2004) (148)
- Pharmacokinetic and electroencephalographic study of intravenous diazepam, midazolam, and placebo (1989) (146)
- Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs (1981) (143)
- Fluoxetine impairs clearance of alprazolam but not of clonazepam (1992) (135)
- Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations. (1999) (134)
- Alterations in drug distribution and clearance due to obesity. (1981) (131)
- Inhibition of Human Cytochrome P450 Isoforms by Nonnucleoside Reverse Transcriptase Inhibitors (2001) (122)
- Ketoconazole inhibition of triazolam and alprazolam clearance: Differential kinetic and dynamic consequences (1998) (121)
- Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences. (2000) (120)
- A double-blind placebo controlled study of desipramine in the treatment ADD: II. Serum drug levels and cardiovascular findings. (1989) (119)
- Alcoholism in women. (1971) (119)
- Alprazolam‐ritonavir interaction: Implications for product labeling (2000) (118)
- Trazodone kinetics: Effect of age, gender, and obesity (1987) (118)
- In Vitro Prediction of the Terfenadine‐Ketoconazole Pharmacokinetic Interaction (1994) (114)
- Metabolism of Drugs by Cytochrome P450 3A Isoforms (1995) (114)
- Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo (1998) (112)
- Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine (1996) (110)
- Antipyrine kinetics in the elderly: prediction of age-related changes in benzodiazepine oxidizing capacity. (1982) (107)
- Absorption and Disposition of Chlordiazepoxide in Young and Elderly Male Volunteers (1977) (103)
- In Vitro, Pharmacokinetic, and Pharmacodynamic Interactions of Ketoconazole and Midazolam in the Rat (2002) (103)
- Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes. (1993) (103)
- Multiple Human Cytochromes Contribute to Biotransformation of Dextromethorphan In‐vitro: Role of CYP2C9, CYP2C19, CYP2D6, and CYP3A (1998) (101)
- Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam. (1989) (99)
- Implications of Altered Drug Disposition in the Elderly: Studies of Benzodiazepines (1989) (98)
- Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: In vitro and clinical studies (2006) (96)
- Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men. (2003) (95)
- N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors. (1995) (95)
- Human cytochromes and some newer antidepressants: kinetics, metabolism, and drug interactions. (1999) (93)
- Clinical Importance of the Interaction of Diazepam and Cimetidine (1984) (93)
- Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences (1998) (93)
- Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam. (1987) (91)
- Anorexia nervosa and affective disorders: a controlled family history study. (1984) (88)
- Desmethyldiazepam kinetics in the elderly after oral prazepam (1980) (87)
- Pomegranate Juice Does Not Impair Clearance of Oral or Intravenous Midazolam, a Probe for Cytochrome P450‐3A Activity: Comparison With Grapefruit Juice (2007) (85)
- Pharmacokinetic Comparison of Sublingual Lorazepam with Intravenous, Intramuscular, and Oral Lorazepam (1982) (84)
- Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects (1999) (84)
- Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo. (1996) (83)
- Diazepam absorption: Effect of antacids and food (1978) (82)
- Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors. (2002) (82)
- Comparison of Duloxetine, Escitalopram, and Sertraline Effects on Cytochrome P450 2D6 Function in Healthy Volunteers (2007) (81)
- Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir (2006) (80)
- Plasma diazepam and desmethyldiazepam concentrations during long-term diazepam therapy. (1981) (80)
- Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate (2004) (80)
- Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions (1999) (79)
- Gender differences in pharmacokinetics and pharmacodynamics of zolpidem following sublingual administration (2014) (79)
- Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics. Flurazepam, temazepam, and triazolam. (1989) (79)
- Human cytochromes mediating N-demethylation of fluoxetine in vitro (1997) (78)
- Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo. (1998) (76)
- Chlordiazepoxide-induced hostility in a small group setting. (1974) (74)
- Absorption rate, blood concentrations, and early response to oral chlordiazepoxide. (1977) (73)
- Impaired absorption of desmethyldiazepam from clorazepate by magnesium aluminum hydroxide (1978) (70)
- Pharmacokinetics and bioavailability of intravenous, intramuscular, and oral lorazepam in humans. (1980) (70)
- Ritonavir is the best alternative to ketoconazole as an index inhibitor of cytochrome P450-3A in drug-drug interaction studies. (2015) (69)
- Comparative single‐dose kinetics and dynamics of lorazepam, alprazolam, prazepam, and placebo (1988) (69)
- Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole (1998) (68)
- Long v short half-life benzodiazepines in the elderly. Kinetics and clinical effects of diazepam and oxazepam. (1983) (66)
- Pharmacokinetic and Pharmacodynamic Interactions Between Zolpidem and Caffeine (2007) (65)
- Absorption and disposition of ibuprofen in the elderly. (1984) (64)
- Extensive impairment of triazolam and alprazolam clearance by short-term low-dose ritonavir: the clinical dilemma of concurrent inhibition and induction. (1999) (63)
- Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: In Vitro and In Vivo Studies (2001) (62)
- Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion. (2009) (61)
- Short‐Term Exposure to Low‐Dose Ritonavir Impairs Clearance and Enhances Adverse Effects of Trazodone (2003) (61)
- Ginkgo biloba Does Not Alter Clearance of Flurbiprofen, a Cytochrome P450‐2C9 Substrate (2006) (61)
- Depressive disorders in relatives of anorexia nervosa patients with and without a current episode of nonbipolar major depression. (1985) (60)
- Pharmacokinetic approach to the clinical use of lidocaine intravenously. (1976) (58)
- Repeated diazepam dosing in cirrhotic patients: Cumulation and sedation (1983) (56)
- Inhibition of Human Cytochrome P450‐3A Isoforms by Fluoxetine and Norfluoxetine: In Vitro and In Vivo Studies (1996) (56)
- Population study of triazolam pharmacokinetics. (1986) (55)
- Bromazepam pharmacokinetics: Influence of age, gender, oral contraceptives, cimetidine, and propranolol (1987) (54)
- Influence of magnesium and aluminum hydroxide mixture on chlordiazepoxide absorption (1976) (54)
- Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies. (1996) (52)
- Lorazepam and oxazepam kinetics in women on low‐dose oral contraceptives (1983) (52)
- Kinetic and dynamic components of increased benzodiazepine sensitivity in aging animals. (1990) (52)
- In vitro metabolism of trazodone by CYP3A: inhibition by ketoconazole and human immunodeficiency viral protease inhibitors (2000) (51)
- Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications. (1993) (48)
- The Absence of an Interaction Between Warfarin and Cranberry Juice: A Randomized, Double‐Blind Trial (2009) (48)
- Patterns of violent behavior among schizophrenic inpatients. (1977) (48)
- The clinician and drug interactions--an update. (1996) (48)
- Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamics. (2005) (48)
- Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation. (2003) (47)
- Pharmacokinetics and Pharmacodynamics of Diphenhydramine 25 mg in Young and Elderly Volunteers (1998) (46)
- Fentanyl Clearance and Volume of Distribution Are Increased in Patients With Major Burns (2007) (46)
- Diagnosis and lithium treatment of affective disorder in the retarded: five case studies. (1979) (44)
- Sedative effects and impaired learning and recall after single oral doses of lorazepam (1986) (43)
- Oxaprozin pharmacokinetics in the elderly. (1985) (43)
- Langner's Psychiatric Impairment Scale: a short screening device. (1971) (43)
- Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation. (2003) (43)
- Cytochromes in psychopharmacology. (1994) (43)
- Pharmacokinetic comparison of sublingual lorazepam with intravenous, intramuscular, and oral lorazepam. (1983) (42)
- Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers (2017) (42)
- Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase. (2009) (42)
- Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin. (1986) (41)
- Dose-independent pharmacokinetics of digoxin in humans. (1978) (41)
- Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily. (2011) (40)
- Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine. (1999) (40)
- Cognitive effects of β‐adrenergic antagonists after single doses: Pharmacokinetics and pharmacodynamics of propranolol, atenolol, lorazepam, and placebo (1993) (39)
- The Neuropsychiatric Effects of Aspartame in Normal Volunteers (1990) (39)
- Psychotropic drugs and induced hostility. (1969) (39)
- Desmethyldiazepam Pharmacokinetics: Studies Following Intravenous and Oral Desmethyldiazepam, Oral Clorazepate, and Intravenous Diazepam (1988) (39)
- Factors influencing diazepam pharmacokinetics: age, sex, and liver disease. (1978) (38)
- The differential effects of chlordiazepoxide and oxazepam on hostility in a small group setting. (1975) (38)
- Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes (2009) (38)
- Human cytochromes mediating sertraline biotransformation: seeking attribution. (1999) (38)
- Prediction of treatment acceptance by child guidance clinic applicants: an easily applied instrument. (1972) (37)
- Psychotropic drug prescribing in the United States: extent, costs, and expenditures. (2011) (36)
- Heterogeneity in anorexia nervosa (1986) (36)
- The effect of benztropine on haloperidol-induced dystonia, clinical efficacy and pharmacokinetics: a prospective, double-blind trial. (1991) (36)
- Comparison of pharmacokinetic profiles of zolpidem buffered sublingual tablet and zolpidem oral immediate-release tablet: results from a single-center, single-dose, randomized, open-label crossover study in healthy adults. (2013) (35)
- Impaired Rivaroxaban Clearance in Mild Renal Insufficiency With Verapamil Coadministration: Potential Implications for Bleeding Risk and Dose Selection (2018) (35)
- Effect of zolpidem on human Cytochrome P450 activity, and on transport mediated by P‐glycoprotein (2002) (34)
- Plasma alprazolam concentrations. Relation to efficacy and side effects in the treatment of panic disorder. (1993) (34)
- Apparent mechanism‐based inhibition of human CYP3A in‐vitro by lopinavir (2003) (34)
- Effect of Age on in Vitro Triazolam Biotransformation in Male Human Liver Microsomes (2004) (33)
- Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition. (1989) (33)
- Adverse reactions to triazolam, flurazepam, and placebo in controlled clinical trials. (1984) (33)
- Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro (2010) (33)
- Pharmocokinetics and pharmacodynamics of single-dose triazolam: electroencephalography compared with the Digit-Symbol Substitution Test. (2005) (32)
- Interaction of Diazepam With Famotidine and Cimetidine, Two H2‐Receptor Antagonists (1986) (32)
- Single‐Dose Pharmacokinetics and Pharmacodynamics of Alprazolam in Elderly and Young Subjects (1998) (31)
- Absence of Interaction of Cimetidine and Ranitidine with Intravenous and Oral Midazolam (1986) (30)
- Zolpidem and Gender: Are Women Really At Risk? (2019) (30)
- A simplex procedure for fitting nonlinear pharmacokinetic models. (1987) (30)
- Update on Psychotropic Drug Prescribing in the United States: 2014-2015. (2017) (29)
- Urinary mhpg in anorexia nervosa patients with and without a concomitant major depressive disorder. (1984) (29)
- Pomegranate Juice and Pomegranate Extract Do Not Impair Oral Clearance of Flurbiprofen in Human Volunteers: Divergence From In Vitro Results (2012) (28)
- Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes. (2000) (28)
- Antipyrine absorption and disposition in the elderly. (1988) (28)
- Venlafaxine and metabolites are very weak inhibitors of human cytochrome P450-3A isoforms (1997) (28)
- Pharmacokinetic properties of benzodiazepine hypnotics. (1983) (27)
- Pharmacokinetics and bioavailability of digoxin capsules, solution and tablets after single and multiple doses. (1978) (27)
- Kinetics and EEG Effects of Midazolam during and after 1‐Minute, 1‐Hour, and 3‐Hour Intravenous Infusions (2004) (25)
- Platelet MAO activity in anorexia nervosa patients with and without a major depressive disorder. (1984) (25)
- Interaction of triazolam and ketoconazole (1995) (24)
- Gas chromatographic analysis of alprazolam in plasma: replicability, stability and specificity. (1990) (24)
- Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen (2015) (24)
- Inhibition of Triazolam Hydroxylation by Ketoconazole, Itraconazole, Hydroxyitraconazole and Fluconazole In‐vitro (1998) (24)
- Effect of age and Billroth gastrectomy on absorption of desmethyldiazepam from clorazepate (1979) (24)
- Noninteraction of temazepam and cimetidine. (1984) (23)
- Kinetic and dynamic interaction of brotizolam and ethanol. (1986) (23)
- Triazolam Kinetics: Interaction with Cimetidine, Propranolol, and the Combination (1988) (23)
- Validity of Self‐Reports of Caffeine Use (1991) (22)
- Zolpidem Pharmacokinetic Properties in Young Females: Influence of Smoking and Oral Contraceptive Use (2002) (21)
- Gepirone and 1-(2-pyrimidinyl)-piperazine in vitro: human cytochromes mediating transformation and cytochrome inhibitory effects (1998) (21)
- Diphenhydramine kinetics following intravenous, oral, and sublingual dimenhydrinate administration. (1990) (21)
- Clearance of the Antihistamine Doxylamine (1989) (19)
- Pharmacokinetics of intravenous caffeine: comparison of high-performance liquid chromatographic and gas chromatographic methods. (1987) (19)
- The pharmacokinetics and pharmacodynamics of sublingual and oral alprazolam in the post-prandial state (1992) (19)
- Plasma concentrations and clinical effects after single oral doses of prazepam, clorazepate, and diazepam. (1984) (19)
- Sandoz Clinical Assessment-Geriatric (SCAG). (1988) (19)
- Characterization of cognitive dysfunction in Sjögren’s syndrome patients (2014) (19)
- Effects of chlordiazepoxide and oxazepam administration on verbal hostility. (1977) (19)
- Sustained Impairment of Lurasidone Clearance After Discontinuation of Posaconazole: Impact of Obesity, and Implications for Patient Safety (2018) (18)
- Molecular and Pharmacokinetic Evaluation of Rat Hepatic and Gastrointestinal Cytochrome P450 Induction by Tamoxifen (2001) (18)
- Psychopharmacologic Investigations in Healthy Elderly Volunteers: MMPI Depression Scale † (1975) (18)
- The therapist variable. (1971) (18)
- MMPI profiles in anorexia nervosa patients with and without major depression (1986) (18)
- Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam (1983) (18)
- Sex differences in diazepam protein binding in patients with renal insufficiency. (1978) (18)
- Benzodiazepines: Safety and toxicity. (1975) (16)
- Clearance of the antihistamine doxylamine. Reduced in elderly men but not in elderly women. (1989) (16)
- The effect of age on sildenafil biotransformation in rat and mouse liver microsomes. (2003) (16)
- Kinetic-dynamic modeling in clinical psychopharmacology. (1993) (16)
- Bioinequivalence of a generic brand of diazepam. (1989) (15)
- Mechanism-based inhibition of human Cytochrome P450-3A activity by grapefruit hybrids having low furanocoumarin content (2012) (15)
- Effect of lipophilicity on drug distribution and elimination: Influence of obesity (2021) (15)
- Lidocaine plasma concentrations following administration of intraoral lidocaine solution. (1985) (15)
- Correlates of outcome following acute glutethimide overdosage. (1979) (15)
- Studies With Stable Isotopes III: Pharmacokinetics of Tracer Doses of Drug (1985) (15)
- Differential effect of cigarette smoking on antipyrine oxidation versus acetaminophen conjugation. (1990) (15)
- High frequency of HLA-Bw16 in patients with anorexia nervosa. (1984) (15)
- Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. (2013) (15)
- Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam. (2000) (15)
- Clonazepam Pharmacokinetics: Comparison of Subcutaneous Microsphere Injection With Multiple‐Dose Oral Administration (2005) (14)
- Single‐Dose Kinetics of Prazepam, a Precursor of Desmethyldiazepam (1979) (14)
- Absolute bioavailability of imipramine: Influence of food (2004) (14)
- A randomized, double-blind trial of the interaction between cranberry juice and warfarin (2008) (14)
- Obesity effects on nitrazepam disposition. (1986) (14)
- Kinetics and dynamics of single doses of oxazepam in the elderly: implications of absorption rate. (1986) (14)
- Changes in salivary antipyrine pharmacokinetics during adolescence, correlated with age, hormonal levels and Tanner stage. (1991) (13)
- HLA haplotype A26–B38 in affective disorders: Lack of association (1987) (13)
- Single- and multiple-dose kinetics of oral lorazepam in humans: The predictability of accumulation (1979) (12)
- Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine. (1998) (12)
- Pharmacokinetics of Zolpidem from Sublingual Zolpidem Tartrate Tablets In Healthy Elderly Versus Non-Elderly Subjects (2014) (12)
- Persistence of a Posaconazole‐Mediated Drug‐Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety (2018) (11)
- Alprazolam hydroxylation by mouse liver microsomes in vitro: the effect of age and phenobarbital induction. (1997) (11)
- Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate (2004) (10)
- Marihuana users and nonusers. Personality test differences. (1972) (10)
- Vortioxetine Disposition in Obesity: Potential Implications for Patient Safety (2018) (10)
- Simplified approaches to the determination of antipyrine pharmacokinetic parameters. (1988) (10)
- Characterological anxiety levels and premenstrual libido changes. (1968) (10)
- Long v short half-life benzodiazepines in the elderly???kinetics and clinical effects of diazepam and oxazepam (1983) (10)
- Influence of food on pharmacokinetics of zolpidem from fast dissolving sublingual zolpidem tartrate tablets (2013) (10)
- Corticosteroid responses to milieu therapy of chronic schizophrenics. (1966) (9)
- Pharmacokinetics of chlordiazepoxide and metabolites following single and multiple oral doses. (1978) (9)
- Response of the elderly to psychotrophic drugs: predictable or idiosyncratic? (1975) (9)
- Towards an Observational Structure for Rating Dysfunction and Pathology in Ambulatory Geriatrics1 (1979) (8)
- Serum digoxin concentrations and subjective manifestations of toxicity. (1980) (8)
- Nefazodone in vitro: Metabolic conversions, and inhibition of P450‐3A isoforms (1996) (8)
- Emergency room study of sedative-hypnotic overdosage: a study of the issues (1982) (7)
- Body Size Changes Among National Collegiate Athletic Association New England Division III Football Players, 1956-2014: Comparison With Age-Matched Population Controls. (2016) (7)
- Falling off the straight line: some hazards of correlation and regression. (1992) (7)
- Absolute bioavailability of imipramine: Influence of food (2004) (7)
- Disposition of clotiazepam: Influence of age, sex, oral contraceptives, cimetidine, isoniazid and ethanol (2004) (7)
- Acetaminophen pharmacokinetics in women receiving conjugated estrogen (2004) (7)
- Sensitivity to Triazolam in the Elderly (1992) (6)
- Benzodiazepine response and receptor binding after chronic ethanol ingestion in a mouse model. (1991) (6)
- Stress and bronchitis. (1968) (5)
- Population Pharmacokinetics of Methylphenidate (1999) (5)
- Tybamate: an examination of its actions in "high" and "low" anxious normals. (1969) (4)
- Arithmetic Versus Harmonic Mean Values of Elimination Half‐Life: A Study of Triazolam (1989) (4)
- Vitamin C prophylaxis and some problems of statistical inference. (1974) (4)
- Diazepam in the Elderly: Looking Back, Ahead, and at the Evidence. (2020) (4)
- Interaction of oxaprozin with acetaminophen, cimetidine, and ranitidine (2004) (4)
- Clinical implications of serum digoxin concentrations (1981) (3)
- Factors influencing blood concentrations of chlordiazepoxide: A use of multiple regression analysis (1977) (3)
- Is oxazepam associated with hostility? (1975) (3)
- A Randomized, Double-Blind Trial of the Interaction between Cranberry Juice and Warfarin. (2006) (3)
- Self-rated sedation and plasma concentrations of desmethyldiazepam following single doses of clorazepate (2004) (3)
- Pharmacokinetic profile of SKP‐1041, a modified release formulation of zaleplon (2011) (3)
- Molindone: a pilot evaluation during the premenstruum. (1975) (3)
- 38 PHARMACOKINETICS , PHARMACODYNAMICS , AND DRUG DISPOSITION (2002) (3)
- Slow Accumulation and Elimination of Diazepam and Its Active Metabolite With Extended Treatment in the Elderly (2020) (2)
- An evaluation of isoquinazepon (SAH-1123). (1967) (2)
- Mechanism of dasabuvir inhibition of acetaminophen glucuronidation. (2021) (2)
- Single versus repeated dosage of the minor tranquilizer chlordiazepoxide (Librium). (1972) (2)
- Regression and Correlation (2015) (2)
- Effect of an Herbal Extract Containing Curcumin and Piperine on Midazolam , Flurbiprofen , and Acetaminophen Pharmacokinetics in Healthy Volunteers (2012) (2)
- Bioequivalence studies in the elderly: a pilot study of two oxazepam dosage forms. (1987) (2)
- Resveratrol glucuronidation in vitro: potential implications of inhibition by probenecid (2018) (2)
- Drug Disposition in Subjects With Obesity: The Research Work of Darrell R. Abernethy (2022) (2)
- Effect of blood collection tubes on antidepressant concentrations. (1987) (2)
- An irreverent look at the t test. (2009) (1)
- Alprazolam, panic disorder, and the new 2 mg tablet. (1991) (1)
- Ritonavir impairs clearance and enhances toxicity of trazodone (2003) (1)
- Contents Vol. 63, 2001 (2001) (1)
- Diurnal Variation of Sodium and Water Metabolism Among Patients with Psychosis, Intermittent Hyponatremia, and Polydipsia (PIP Syndrome) (1987) (1)
- Clinically unimportant pharmacokinetic drug interaction between fluvoxamine and single doses of caffeine (2005) (1)
- An investigation of the stimulating and mood-elevating properties of pipradol HCl administered to clinically normal volunteers. (1968) (1)
- The UGT2B15*2 polymorphism is a major determinant of oxazepam clearance in human volunteers. (2009) (0)
- Comparative effects of single and repeat dose administration of antianxiety agents. (1971) (0)
- Subject Index Vol. 63, 2001 (2001) (0)
- Menarcheal Age and Personality: The Choice of a Statistical Test of Relationship (1974) (0)
- Planning Pharmaceutical Clinical Trials. Basic Statistical Principles (1995) (0)
- Steady-state plasma desmethyldiazepam during long-term clorazepate use: effect of antacids (1982) (0)
- Tentative Approaches to Testing Elderly Volunteers in a Drug Trial. (1976) (0)
- Thinking while balancing: what to do about replacing dropouts. (1994) (0)
- Twenty-five years of recurring methods questions in a clinical psychopharmacology laboratory (1992) (0)
- Recovery of CYP3A function following single doses of grapefruit juice (2003) (0)
- Letter: Correlation of human menstruation and lunar phase. (1975) (0)
- Cytochrome P 450-3 A Activity : Comparison With Grapefruit Juice Pomegranate Juice Does Not Impair Clearance of Oral or Intravenous Midazolam , a Probe for (2007) (0)
- Chlordiazepoxide and Hostility (2015) (0)
- with the highly significant reduction in clearance of the oxidized benzodiazepine diazepam. (1982) (0)
- Kinetic anddynamic interaction ofbrotizolam andethanol (1986) (0)
- The effect of age on triazolam hydroxylation in human liver microsomes from males (2003) (0)
- CLINICAL PHARMACOKINETICS OF LORAZEPAM 4, LONG-TERM ORAL ADMINISTRATION (1978) (0)
- W-D-017 PHARMACOKINETIC PROFILE OF A MODIFIED RELEASE FORMULATION OF ZALEPLON (SKP-1041) 10.0 MG, 15.0 MG, AND 20.0 MG IN ADULTSWITH PRIMARY SLEEP MAINTENANCE INSOMNIA (2011) (0)
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