J. Timothy Smith

J. Timothy Smith's AcademicInfluence.com Rankings

J. Timothy Smith

Philosophy

#8998

World Rank

#12488

Historical Rank

Ontology

#110

World Rank

#123

Historical Rank

Logic

#6005

World Rank

#7477

Historical Rank

philosophy Degrees

J. Timothy Smith

Biology

#12292

World Rank

#15758

Historical Rank

Microbiology

#731

World Rank

#805

Historical Rank

biology Degrees

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Philosophy
Biology

J. Timothy Smith's Degrees

PhD Microbiology University of California, San Francisco
Doctorate Medicine University of California, San Francisco

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J. Timothy Smith's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Nalidixic Acid: an Antibacterial Paradox (1975) (178)
Molecular Specificities of R Factor-Determined Beta-Lactamases: Correlation with Plasmid Compatibility (1974) (167)
The mode of action of 4-quinolones and possible mechanisms of resistance. (1986) (125)
Types of beta-lactamase determined by plasmids in gram-negative bacteria (1979) (122)
R-factor trimethoprim resistance mechanism: an insusceptible target site. (1974) (114)
4-quinolones and the SOS response. (1989) (94)
R-Factor-Mediated β-Lactamases That Hydrolyze Oxacillin: Evidence for Two Distinct Groups (1974) (90)
2 – Chemistry and Mechanisms of Action of the Quinolone Antibacterials (1988) (88)
Evaluation of sperm concentration by the hemacytometer method; comparison of four counting fluids. (1955) (87)
Nalidixic acid and bacterial chromosome replication (1976) (79)
The nature of penicillin resistance in staphylococci. (1961) (70)
R-factor gene expression gram-negative bacteria. (1969) (65)
The purification and properties of the -lactamase specified by the resistance factor R-1818 in Escherichia coli and Proteus mirabilis. (1971) (63)
Trimethoprim Action and Its Analogy with Thymine Starvation (1974) (59)
Bactrecidal mechanisms of ofloxacin (1988) (56)
Penicillinase and ampicillin resistance in a strain of Escherichia coli. (1963) (56)
Interaction of Cephaloridine with Penicillinase-Producing Gram-Negative Bacteria (1965) (52)
Properties of an R factor from Bordetella bronchiseptica. (1974) (51)
Bacterial resistance to penicillins and cephalosporins (1969) (48)
R-factor mediated trimethoprim resistance: result of two three-month clinical surveys. (1978) (48)
R factor-mediated resistance to ultraviolet light in strains of Escherichia coli deficient in known repair functions. (1976) (48)
The mode of action of quinolones: The paradox in activity of low and high concentrations and activity in the anaerobic environment (1991) (47)
Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli (1976) (44)
THE ESTIMATION OF PENICILLINS AND PENICILLIN DESTRUCTION (1963) (43)
Differences between Pencillinases from Gram-Positive and Gram-Negative Bacteria (1963) (38)
Mechanisms of antimicrobial resistance and implications for epidemiology. (1993) (38)
Inhibition of Penicillinases from Gram-Positive and Gram-Negative Bacteria by Substrate Analogues (1964) (38)
Isoxazolyl Penicillins and Penicillinase (1962) (37)
Protein- and RNA-synthesis independent bactericidal activity of ciprofloxacin that involves the A subunit of DNA gyrase. (1991) (35)
Effect of Pencillinase on the Activity of Penicillins: Potentiation of Penicillin Action by Inhibition of Penicillinase (1964) (35)
The dimeric nature of an R-factor mediated β-lactamase (1976) (34)
Function of the SOS Process in Repair of DNA Damage Induced by Modern 4‐Quinolones (1993) (33)
Antibacterial activity, penicillinase stability and inducing ability of different penicillins. (1962) (33)
Bactericidal mechanisms of ofloxacin. (1988) (33)
Mutational resistance to 4-quinolone antibacterial agents (1984) (31)
Stability of Methicillin and Cloxacillin to Staphylococcal Penicillinase (1963) (27)
A comparison of the utilization of organic and inorganic sulfur by the rat. (1965) (27)
Sulphydryl Groups Essential for the Penicillinase Activity of Aerobacter cloacae (1963) (26)
NORFLOXACIN HAS A NOVEL BACTERICIDAL MECHANISM UNRELATED TO THAT OF OTHER 4‐QUINOLONES (1985) (26)
Effect of vitamin E deficiency on collagen metabolism in the rat's skin. (1967) (26)
R-factor mediated dihydrofolate reductases which confer trimethoprim resistance. (1978) (26)
Plasmid-Determined , B-Lactamase Indistinguishable from the Chromosomal , 3-Lactamase of Escherichia coli (26)
Use of Cellulose Acetate Membranes for detecting Penicillinase-producing Organisms (1961) (25)
4-Quinolone bactericidal mechanisms. (1993) (25)
The importance of oxygen in the killing of bacteria by ofloxacin and ciprofloxacin. (1994) (22)
A rapid method for the assay of small quantities of sulfomucopolysaccharides. (1965) (22)
R-factor elimination by thymine starvation. (1971) (22)
Production of thymineless mutants in gram-negative bacteria (Aerobacter, Proteus). (1967) (21)
Trimethoprim-sensitivity testing and thymineless mutants. (1974) (21)
The bactericidal activity of sparfloxacin. (1992) (21)
Thymineless mutants and their resistance to trimethoprim. (1975) (20)
Penicillinases from Gram-Positive and Gram-Negative Bacteria: A Thermodynamic Difference (1963) (20)
Ampicillin Resistance of Shigella sonnei (1974) (20)
Relation of R Factor and Chromosomal β-Lactamase with the Periplasmic Space (1974) (20)
The purification and properties of the trimethoprim-resistant dihydrofolate reductase mediated by the R-factor, R388. (1976) (19)
Hetacillin: a chemical and biological comparison with ampicillin. (1970) (19)
The Fluoroquinolones Exert a Reduced Rate of Kill Against Enterococcus faecalis (1991) (19)
R Factor Elimination During Thymine Starvation: Effects of Inhibition of Protein Synthesis and Readdition of Thymine (1972) (18)
Classification of trimethoprim-resistant dihydrofolate reductases mediated by R-plasmids using isoelectric focussing. (1982) (18)
Fertility inhibition of an N group R factor by a group X R factor, R6K. (1974) (17)
Joint trimethoprim and sulphamethoxazole resistance in bacteria infected with R factors. (1973) (17)
A direct comparison of two unusual R-factor-mediated -lactamases. (1972) (17)
The effect of R-factor plasmids on host-cell responses to nalidixic acid I. Increased susceptibility of nalidixic acid-sensitive hosts. (1981) (16)
Bacterial resistance to antifolate chemotherapeutic agents mediated by plasmids. (1984) (16)
Some relationships between R-factor and chromosomal -lactamase in Gram-negative bacteria. (1971) (15)
A follow-up survey of transferable, plasmid-encoded trimethoprim resistance in a general hospital (1975-1983). (1985) (15)
Changes in collagen metabolism caused by feeding diets low in inorganic sulfur. (1965) (15)
Post-antibiotic effects of ofloxacin on Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes. (1993) (15)
Cellular lipoproteins. I. The insoluble lipoprotein of whole liver cells. (1957) (15)
Interactions of the 4-quinolones with other antibacterials. (1989) (14)
R-Factor-Mediated Nuclease Activity Involved in Thymineless Elimination (1974) (14)
Bactericidal activity of the new 4-quinolones DU-6859a and DV-7751a. (1995) (14)
An optimal level of inorganic sulfate for the diet of a rat. (1973) (13)
A relationship between vitamin B12, folic acid, ascorbic acid, and mercury uptake and methylation. (1990) (13)
Activity of 4-quinolones against Pseudomonas aeruginosa. (1994) (13)
Creatine metabolism in the pyridoxine-deficient rat. (1986) (13)
[Mechanism of action of quinolones]. (1986) (13)
In vitro effects of fibrous and nonfibrous silicon nitride on bovine pulmonary macrophages. (1989) (12)
Effect of dietary sulfur on serum cholesterol and the glycocholic:taurocholic acid ratio of the rat. (1973) (12)
Quinacillin : A Comparison with other Penicillinase-Resistant Penicillins (1964) (12)
Envelope alterations produced by R factors in Proteus mirabilis. (1974) (12)
EFFECT OF SULFANILAMIDE ON THE OXYGEN CAPACITY OF THE BLOOD (1938) (12)
Trimethoprim antagonists: effect of uridine in laboratory media. (1978) (12)
A metabolic comparison of cysteine and methionine supplements in the diet of a rat. (1983) (12)
DNA breakdown by the 4-quinolones and its significance. (1990) (11)
Utilization of calcium and sodium sulfate by the rat. (1965) (11)
The Influence of Oxygen upon Bactericidal Potency (1990) (11)
Bactericidal activity of enoxacin and Lomefloxacin againstEscherichia coli KL16 (1989) (10)
Seasonal Variation in the Succinic Dehydrogenase Activity of Bovine Spermatozoa (1957) (10)
Effect of Egg yolk and its Isolated Constituents Upon the Dehydrogenase Activity of Bovine Spermatozoa (1956) (9)
The effect of sulfate deficiency on the mechanical strength of the rat's aorta. (1965) (9)
Curing of an R Factor from Escherichia coli by Trimethoprim (1973) (9)
Resistance to the Newer Penicillins (1963) (9)
Properties of binary complexes between metal ions and glyoxalic or alphaketoglutaric or imidazolypyruvic acid (1975) (9)
An effect of dietary sulfur on liver inorganic sulfate in the rat. (1983) (9)
Contributions of post-antibiotic lag and repair-recovery to the post-antibiotic effects of ciprofloxacin on Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus pyogenes. (1993) (8)
4-quinolones and multivalent ions. (1990) (8)
Effect of dietary sulfur on taurine excretion by the rat. (1974) (8)
A hypothesis for a common mode of action of the fat soluble vitamins A, D, and E. (1963) (8)
The effect of a plasmid on growth and survival of E. coli (2004) (8)
Conditions required for the bactericidal activity of 4-quinolones against Serratia marcescens. (1990) (8)
Bactericidal activity of ciprofloxacin against Staphylococcus aureus. (1989) (7)
Pulmonary Response to Intratracheally Instilled Silicon Nitride in Rats (1989) (7)
BRL 1621: A Comparison with Other Isoxazolyl Penicillins (1962) (7)
4-Quinolone interactions with gyrase subunit B inhibitors. (1991) (7)
Trimethoprim antagonists: effect of uridine on thymine and thymidine uptake in mineral salts medium (1978) (7)
The influence of cysteine and methionine supplements on polyamine biosynthesis in the rat. (1983) (7)
A Comparison of the Ability of Certain Egg Yolk Diluents to Maintain Optimum Osmotic Conditions during the Storage of Bull Semen (1954) (6)
GAIN OF ANTIBIOTIC SENSITIVITY ACCOMPANYING EMERGENCE OF CLINICAL CIPROFLOXACIN RESISTANCE (1988) (6)
Escherichia coli 5'-nucleotidase: purification, properties and its release by osmotic shock. (1981) (6)
Effects of Physiological Cation Concentration on 4-Quinolone Absorption and Potency (1990) (5)
In Vitro and In Vivo Mutation Frequencies to Resistance — do they Correlate in the Long Term? (1990) (5)
Relation of R factor and chromosomal beta-lactamase with the periplasmic space. (1974) (5)
Interactions of 4-Quinolones with Other Agents — The Importance in Assessing Practical Antibacterial Potency (1990) (4)
Frequency and expression of mutational resistance to the 4-quinolone antibacterials. (1986) (4)
Studies on mutational cross-resistance between ciprofloxacin, novobiocin and coumermycin in Escherichia coli and Staphylococcus warneri. (1993) (4)
Mutation rates to 4-quinolone resistance. (1990) (4)
Curing of an R factor from Escherichia coli by hydroxyurea and cytosine arabinoside. (1978) (4)
Antibiotic resistance levels of bacteria harbouring more than one R factor. (1974) (4)
R‐factor mediated resistance to ultraviolet light (1974) (4)
Ofloxacin, a bactericidal antibacterial. (1991) (4)
[Effect of pH value and magnesium on the antibacterial activity of quinolone preparations]. (1986) (4)
Loss of ciprofloxacin's second killing action in Escherichia coli that have developed 4-quinolone resistance during therapy. (1990) (4)
Antagonism between bactericidal activities of 4-quinolones and coumarins gives insight into 4-quinolone killing mechanisms. (1994) (4)
Post-antibiotic effects of cefdinir on Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus pyrogenes. (1994) (4)
Effect of avitaminosis E on the incorporation of 35S-sulfate by rat tissue components. (1970) (4)
Trimethoprim resistance controlled by a combination of plasmid and chromosomal genes. (1977) (3)
Dislodgement and thymineless elimination of N-group plasmids. (1977) (3)
Absence of bactericidal activity of sparfloxacin and ciprofloxacin under anaerobic conditions. (1992) (3)
Effect of Washing upon the Dehydrogenase Activity of Bovine Spermatozoa (1957) (3)
R-plasmid effects on bacterial multiplication and survival (1983) (3)
The dimeric nature of an R-factor mediated beta-lactamase. (1976) (3)
A method for determining tissue sulfate. (1981) (3)
Elimination of an R-factor by trimethoprim. (1972) (2)
The bactericidal activity of ofloxacin against staphylococci. (1989) (2)
UNUSUAL PATTERNS OF ANTIBIOTIC RESISTANCE FROM A CLINICALLY ISOLATED R‐FACTOR (1978) (2)
The New 4-Quinolones DU-6859a and DV-7751a Show Enhanced Activity against Streptococcus pneumoniae (2012) (2)
Inhibition of mitochondrial palmitate oxidation by calmodulin antagonists. (1990) (2)
Proceedings: R-Factor conferred ability to mutate to trimethoprim resistance. (1975) (2)
DO R‐FACTORS AFFECT THE ABILITY OF HOST BACTERIA TO COMPETE FOR NUTRIENTS? (1978) (2)
Activity of Quinolone Antibacterials against Streptococcus pneumoniae (2012) (2)
Effect of S-adenosylhomocysteine on sulfhydryl xenobiotic transmethylases in rat liver. (1985) (2)
A Comparison of the In Vivo and In Vitro Toxicity of Fibrous and Non-Fibrous Silicon Nitride (1989) (2)
DETECTION OF A THIRD BACTERIAL MECHANISM IN CIPROFLOXACIN AND OFLOXACIN (1986) (2)
Interaction between the plasmid R6K and Escherichia coli with defective DNA polymerase I. (1978) (2)
INTERACTIONS BETWEEN THE BACTERICIDAL EFFECTS OF 4‐QUINOLONES AND OTHER GYRASE INHIBITORS ACTING ON STAPHYLOCOCCI (1990) (1)
Proceedings: Inhibitors of thymidylate synthetase as R factor curing agents. (1973) (1)
EFFECT OF NALIDIXIC ACID ON BACTERIA POSSESSING MUTATIONS IN THE RECA AND LEXA GENES (1986) (1)
R factor elimination by inhibitors of thymidhlate synthetase (fluorodeoxyuridine and showdomycin) and the occurrence of single strand breaks in plasmid DNA (2004) (1)
Glutathione: an endogenous substrate for thiopurine methyltransferase? (1985) (1)
CALORIMETRIC INVESTIGATIONS OF ESCHERICHIA COLI TREATED WITH CIPROFLOXACIN AND NALIDIXIC ACID (1986) (1)
Effects of temperature on the bactericidal activities of ciprofloxacin and levofloxacin against Escherichia coli and Pseudomonas aeruginosa. (1994) (1)
Effects of temperature on the bactericidal activities of ciprofloxacin and levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis. (1994) (1)
RELEASE OF ENZYMES FROM BACTERIA (1979) (1)
THE EFFECTS OF AN R‐FACTOR AND ITS NON‐TRANSMISSIBLE DERIVATIVE ON THE SURVIVAL OF BACTERIA IN MEDIA CONTAINING MITOMYCIN C (1979) (0)
A relationship between the fatty acid composition and the melting point of lipid from obese (ob/ob) and lean (ob/?) mice (1991) (0)
CURING OF AN R FACT ' OR BY TRIMETHOP ' RIN (0)
Some Relationships between R-Factor and Chromosomal p-Lactamase in Gram-Negative Bacteria (2005) (0)
A dietary effect upon the eating habits of mice. (1990) (0)
An effect of dietary sulfur upon opiate metabolism and excretion (1984) (0)
Penicillinase in two strains of Aerobacter cloacae isolated from the same patient. (1970) (0)
Inhibition of R-factor-mediated β-lactamase by Proteus mirabilis (2004) (0)
The assay of penicillins (1964) (0)
calcium phosphate phases to support the bone cell activity particularly suitable stabilized composition of (1996) (0)
Antagonism of aminoglycoside antibiotic action [proceedings]. (1977) (0)
R factor elimination from Escherichia coli by hydroxyurea and cytosine arabinoside [proceedings]. (1976) (0)
Activity of New 4-Quinolones in Combination with Erythromycin or Tetracycline against S. pneumoniae (2012) (0)
An investigation of hepatic cytochrome b5 levels and hydrogen peroxide production in normal and obese (ob/ob) mice. Abstr. (1983) (0)
Escherichia coli thymine auxotrophs suppressible by carbon dioxide. (1985) (0)
Drug-Inactivating Enzymes and Antibiotic Resistance (1976) (0)
Understanding the MIC of beta-lactam antibiotics. (1989) (0)
Eating habits of obese (OB/OB) and normal mice (1989) (0)
An investigation of hepatic cytochrome p-450 levels in normal and obese (ob/ob) mice. Abstr. (1976) (0)
Release of enzymes from bacteria [proceedings]. (1979) (0)
Trimethoprim antagonists: effect of uridine on thymine uptake in mineral salts medium. (1978) (0)
A COMPARISON OF THE ALTERATION OF THE DIETARY FATTY ACID PATTERN TO A CARCASS FATTY ACID PATTERN BY OBESE (OB/OB) AND LEAN (OB/?) MICE (1990) (0)
Clinical impact of in vitro data with newer quinolones. (1989) (0)
Proceedings: R-Factor replication in an E. coli host with defective polymerase I. (1975) (0)
Influence of temperature on mutational resistance to 4-quinolones. (1996) (0)
ABSENCE OF BACTERIAL ACTIVITY OF SPARFLOXACIN AND CIPROFLOXACIN UNDER ANAEROBIC CONDITIONS. AUTHOR'S REPLY (1992) (0)
Expression of resistance to quinolone antimicrobials. (1987) (0)
Proceedings: R-factor mediated resistance to ultraviolet light. (1974) (0)
Down-regulation of rat liver beta-adrenergic receptors by cysteine. (1986) (0)
Em Response of a Conductive, Permeable Spherical Shell (2005) (0)
Interactions between 4-quinolone antibacterials and multivalent metal ions. (1989) (0)
Substrate cycling between fructose 6-phosphate and fructose 1,6-diphosphate does not contribute to metabolic obesity. (1990) (0)
An effect of sulfur nutrition on the metabolism of salicylamide. (1982) (0)
Salmonella tYphimurium Authors ' laboratory LT 2 using the techniques of Miles and Misra (0)
Inhibition of R-factor-mediated beta-lactamase by Proteus mirabilis. (1974) (0)
Antagonism in sulphonamide sensitivity testing [proceedings]. (1976) (0)

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J. Timothy Smith is affiliated with the following schools:

University of Auckland

J. Timothy Smith's Academic­Influence.com Rankings

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Why Is J. Timothy Smith Influential?

J. Timothy Smith's Published Works

Published Works

What Schools Are Affiliated With J. Timothy Smith?

J. Timothy Smith's AcademicInfluence.com Rankings