Jaap Verweij
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Philosophy
Jaap Verweij's Degrees
- PhD Medical Oncology University of Amsterdam
- Doctorate Medicine University of Amsterdam
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(Suggest an Edit or Addition)Jaap Verweij's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). (2009) (17488)
- New Guidelines to Evaluate the Response to Treatment in Solid Tumors. (2000) (11951)
- New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. (2000) (8707)
- New guidelines to evaluate the response to treatment in solid tumors (2000) (3518)
- Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial (2006) (2326)
- Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. (2001) (1466)
- Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study (2001) (1307)
- Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial (2004) (1269)
- KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. (2006) (836)
- Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial. (2014) (808)
- Clinical pharmacokinetics and metabolism of irinotecan (CPT-11). (2001) (706)
- Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. (2012) (632)
- Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). (2009) (611)
- Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas. (2009) (591)
- Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study. (2010) (590)
- Soft tissue sarcomas of adults: state of the translational science. (2003) (559)
- Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma: an analysis of 2,185 patients treated with anthracycline-containing first-line regimens--a European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study. (1999) (512)
- Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. (1995) (496)
- Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group. (2004) (449)
- RECIST revisited: a review of validation studies on tumour assessment. (2006) (438)
- Effects of St. John's wort on irinotecan metabolism. (2002) (429)
- Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer. (1998) (425)
- Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial. (2012) (414)
- Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial. (2005) (413)
- Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: results of a large European phase II study. (1996) (406)
- Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas. (2002) (396)
- Pharmacological Effects of Formulation Vehicles (2003) (395)
- Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg. (2005) (375)
- Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists. (1997) (357)
- Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications. (1999) (353)
- Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. (2000) (341)
- Paclitaxel (Taxol) and docetaxel (Taxotere): not simply two of a kind. (1994) (337)
- The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review. (2006) (332)
- Randomised phase II trial of pegylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: a study by the EORTC Soft Tissue and Bone Sarcoma Group. (2001) (324)
- A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma. (2001) (320)
- Precision oncology: an overview. (2013) (302)
- Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study. (2005) (285)
- Role of Formulation Vehicles in Taxane Pharmacology (2001) (282)
- Irinotecan pathway genotype analysis to predict pharmacokinetics. (2003) (270)
- Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer. (1998) (268)
- Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001. (2002) (267)
- Docetaxel (Taxotere): an active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. (1994) (260)
- Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype (2004) (253)
- Clinical Pharmacokinetics of Docetaxel (2006) (242)
- Phase III trial of two investigational schedules of ifosfamide compared with standard-dose doxorubicin in advanced or metastatic soft tissue sarcoma: a European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study. (2007) (240)
- Docetaxel (Taxotere) in advanced gastric cancer: results of a phase II clinical trial. EORTC Early Clinical Trials Group. (1994) (239)
- Topoisomerase I inhibitors: topotecan and irenotecan. (1994) (236)
- Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: a report of the EORTC Soft Tissue and Bone Sarcoma Group. (2002) (234)
- Pharmacogenetics of ABCG2 and adverse reactions to gefitinib. (2006) (230)
- Ondansetron compared with high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. A multicenter, randomized, double-blind, crossover study. (1990) (230)
- Randomized phase III study comparing conventional-dose doxorubicin plus ifosfamide versus high-dose doxorubicin plus ifosfamide plus recombinant human granulocyte-macrophage colony-stimulating factor in advanced soft tissue sarcomas: A trial of the European Organization for Research and Treatment of (2000) (226)
- Mitomycin C: mechanism of action, usefulness and limitations. (1990) (225)
- A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours (2007) (223)
- Weekly high-dose cisplatin is a feasible treatment option: analysis on prognostic factors for toxicity in 400 patients (2003) (220)
- Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins αvβ3 and αvβ5 in patients with advanced solid tumours (2003) (213)
- Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps (2005) (209)
- miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells (2013) (209)
- Paclitaxel in patients with advanced angiosarcomas of soft tissue: a retrospective study of the EORTC soft tissue and bone sarcoma group. (2008) (201)
- Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas: an exploratory, retrospective analysis on large series from the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcom (2010) (194)
- Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial (2018) (192)
- Complementary and alternative medicine during cancer treatment: beyond innocence. (2006) (190)
- Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group (2005) (189)
- Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmacokinetics of Paclitaxel (2005) (187)
- Drug transporters of platinum-based anticancer agents and their clinical significance. (2011) (187)
- Dosing strategies for anticancer drugs: the good, the bad and body-surface area. (2002) (182)
- Phase II trial of CPT-11 in patients with advanced pancreatic cancer, an EORTC early clinical trials group study. (1995) (182)
- Individual patient data analysis to assess modifications to the RECIST criteria. (2009) (180)
- Outcome of Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era (2012) (180)
- Modulation of irinotecan-induced diarrhea by cotreatment with neomycin in cancer patients. (2001) (178)
- Alternative drug formulations of docetaxel: a review. (2007) (177)
- Advanced soft-tissue sarcoma: a disease that is potentially curable for a subset of patients treated with chemotherapy. (2003) (173)
- DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours (2010) (168)
- Pharmacogenetic Pathway Analysis of Docetaxel Elimination (2009) (167)
- Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first- and second-line chemotherapy in advanced soft tissue sarcoma patients. (2002) (165)
- Irinotecan‐induced Diarrhea: Functional Significance of the Polymorphic ABCC2 Transporter Protein (2007) (162)
- Mechanism-based pharmacokinetic model for paclitaxel. (2001) (161)
- Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese. (2007) (157)
- Effect of food on the pharmacokinetics of capecitabine and its metabolites following oral administration in cancer patients. (1998) (157)
- Effect of ABCG2 genotype on the oral vioavailability of topotecan (2005) (156)
- Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours. (1996) (156)
- Variants in the SLCO1B3 Gene: Interethnic Distribution and Association with Paclitaxel Pharmacokinetics (2007) (155)
- Drug Transporters and Imatinib Treatment: Implications for Clinical Practice (2010) (155)
- Interaction of Cisplatin with the Human Organic Cation Transporter 2 (2008) (152)
- ABCG2 Pharmacogenetics (2004) (151)
- 32 INVITED New response evaluation criteria in solid tumors: revised RECIST guideline version 1.1 (2008) (150)
- Effect of high-dose ifosfamide in advanced soft tissue sarcomas. A multicentre phase II study of the EORTC Soft Tissue and Bone Sarcoma Group. (2000) (147)
- Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib (2006) (147)
- Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development. (1997) (142)
- Matrix metalloproteinase inhibitors: current developments and future perspectives. (2001) (140)
- A phase II trial with docetaxel (Taxotere) in second line treatment with chemotherapy for advanced breast cancer. A study of the EORTC Early Clinical Trials Group. (1994) (138)
- Bioavailability and pharmacokinetics of oral topotecan: a new topoisomerase I inhibitor. (1996) (136)
- Effects of granulocyte-macrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients. (1998) (136)
- Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes. (2004) (135)
- Factors Affecting Cytochrome P-450 3A Activity in Cancer Patients (2004) (134)
- Effective cross-over to granisetron after failure to ondansetron, a randomized double blind study in patients failing ondansetron plus dexamethasone during the first 24 hours following highly emetogenic chemotherapy (2001) (134)
- Doxorubicin-based adjuvant chemotherapy in soft tissue sarcoma: pooled analysis of two STBSG-EORTC phase III clinical trials. (2014) (134)
- Determining the optimal dose in the development of anticancer agents (2014) (134)
- Granulocyte-macrophage colony-stimulating factor allows safe escalation of dose-intensity of chemotherapy in metastatic adult soft tissue sarcomas: a study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. (1993) (133)
- A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas. (2012) (131)
- Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer. (2001) (131)
- A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck (1994) (131)
- (Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor. (2010) (130)
- Flat-fixed dosing versus body surface area based dosing of anticancer drugs in adults: does it make a difference? (2007) (130)
- Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia. (2007) (128)
- Phase II study with Docetaxel (Taxotere®) in advanced soft tissue sarcomas of the adult (1994) (128)
- Docetaxel: an active new drug for treatment of advanced epithelial ovarian cancer. (1995) (127)
- Comparative Pharmacokinetics of Weekly and Every-Three-Weeks Docetaxel (2004) (126)
- Body-surface area-based dosing does not increase accuracy of predicting cisplatin exposure. (2001) (126)
- Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan. (2002) (124)
- Irinotecan (CPT-11) metabolism and disposition in cancer patients. (1998) (124)
- Peripheral neurotoxicity induced by docetaxel (1996) (122)
- Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor. (1993) (121)
- Modulation of irinotecan metabolism by ketoconazole. (2002) (121)
- Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2. (2005) (121)
- Complete Longitudinal Analyses of the Randomized, Placebo-Controlled, Phase III Trial of Sunitinib in Patients with Gastrointestinal Stromal Tumor following Imatinib Failure (2012) (120)
- Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice. (1999) (120)
- Phase I and pharmacokinetic study of the oral farnesyl transferase inhibitor SCH 66336 given twice daily to patients with advanced solid tumors. (2001) (120)
- Clinical pharmacokinetics of irinotecan and its metabolites in relation with diarrhea (2002) (117)
- Docetaxel (Taxotere): an active agent in metastatic urothelial cancer; results of a phase II study in non-chemotherapy-pretreated patients. (1998) (115)
- Gemcitabine in advanced adult soft-tissue sarcomas. A phase II study of the EORTC Soft Tissue and Bone Sarcoma Group. (2002) (115)
- Influence of Genetic Variants in UGT1A1 and UGT1A9 on the In Vivo Glucuronidation of SN‐38 (2004) (114)
- Effect of Cytochrome P450 3A4 Inhibition on the Pharmacokinetics of Docetaxel (2004) (114)
- Impact of body-size measures on irinotecan clearance: alternative dosing recommendations. (2002) (114)
- Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up. (2008) (112)
- Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointestinal Trials Group Intergroup Phase III Randomized Tr (2017) (110)
- Clinical pharmacokinetics of unbound docetaxel: Role of polysorbate 80 and serum proteins (2003) (110)
- Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents--dose-Limiting Toxicity and Toxicity Assessment Recommendation Group for Early Trials of Targeted therapies, an European Organisation fo (2014) (109)
- Modulation of camptothecin analogs in the treatment of cancer: a review (2001) (109)
- Role of pharmacogenetics in irinotecan therapy. (2006) (108)
- Prospective evaluation of the pharmacokinetics and toxicity profile of docetaxel in the elderly. (2004) (107)
- Mapatumumab, a Fully Human Agonistic Monoclonal Antibody That Targets TRAIL-R1, in Combination with Gemcitabine and Cisplatin: a Phase I Study (2009) (105)
- High-dose DTIC in advanced soft-tissue sarcomas in the adult. A phase II study of the E.O.R.T.C. Soft Tissue and Bone Sarcoma Group. (1991) (105)
- Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre. (2005) (105)
- Docetaxel and cisplatin: an active regimen in patients with locally advanced, recurrent or metastatic squamous cell carcinoma of the head and neck. Results of a phase II study of the EORTC Early Clinical Studies Group. (1999) (105)
- Measurement of fraction unbound paclitaxel in human plasma. (2000) (104)
- A Long-term Prospective Population Pharmacokinetic Study on Imatinib Plasma Concentrations in GIST Patients (2012) (104)
- Phase I pharmacokinetic and pharmacodynamic study of the aurora kinase inhibitor danusertib in patients with advanced or metastatic solid tumors. (2009) (103)
- Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer. EORTC Head and Neck Cooperative Group. (1999) (103)
- A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours (2000) (101)
- The potential of statins as part of anti-cancer treatment. (2005) (101)
- Lessons learned from independent central review. (2009) (101)
- The role of CA 125 in the early diagnosis of progressive disease in ovarian cancer. (1990) (100)
- Docetaxel administration schedule: from fever to tears? A review of randomised studies. (2005) (99)
- Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial. (2009) (99)
- The orally administered P-glycoprotein inhibitor R101933 does not alter the plasma pharmacokinetics of docetaxel. (2000) (99)
- Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer. (2005) (99)
- Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: a study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Trials Group (EORTC-ISG-AGITG). (2006) (99)
- Clinical characteristics of severe peripheral neuropathy induced by docetaxel (Taxotere). (1997) (98)
- Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: analysis of EORTC-ISG-AGITG study 62005. (2007) (98)
- Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours. (2003) (98)
- Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo. (1998) (98)
- SDHA mutations in adult and pediatric wild-type gastrointestinal stromal tumors (2013) (97)
- High-dose epirubicin is not an alternative to standard-dose doxorubicin in the treatment of advanced soft tissue sarcomas. A study of the EORTC soft tissue and bone sarcoma group. (1998) (96)
- Potential for improvement of docetaxel-based chemotherapy: a pharmacological review (2005) (96)
- A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors (2004) (95)
- Clinical pharmacokinetics of irinotecan and its metabolites: a population analysis. (2002) (94)
- Influence of Cremophor El on the bioavailability of intraperitoneal paclitaxel. (2002) (94)
- Relationship of Systemic Exposure to Unbound Docetaxel and Neutropenia (2005) (92)
- Treatment of patients with metastatic pancreatic and gastrointestinal tumours with the somatostatin analogue Sandostatin: a phase II study including endocrine effects. (1990) (90)
- Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors (2011) (90)
- Ifosfamide plus doxorubicin in previously untreated patients with advanced soft-tissue sarcoma. (1993) (90)
- Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072. (2014) (89)
- Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein. (1999) (88)
- Weekly cisplatin and daily oral etoposide is highly effective in platinum pretreated ovarian cancer (2002) (88)
- Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours. (2006) (87)
- Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans. (2000) (86)
- Comparative pharmacokinetics of unbound paclitaxel during 1- and 3-hour infusions. (2002) (86)
- CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity (2013) (86)
- Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study. (2006) (86)
- Phase I Pharmacokinetic, Food Effect, and Pharmacogenetic Study of Oral Irinotecan Given as Semisolid Matrix Capsules in Patients with Solid Tumors (2005) (85)
- Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38 (2004) (85)
- Using single-agent therapy in adult patients with advanced soft tissue sarcoma can still be considered standard care. (2005) (85)
- Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up. (2008) (84)
- Determination of paclitaxel in human plasma using single solvent extraction prior to isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection. (1998) (83)
- Determination of doxorubicin and doxorubicinol in plasma of cancer patients by high-performance liquid chromatography. (1999) (82)
- Paclitaxel (Taxol) induces cumulative mild neurotoxicity. (1994) (81)
- Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group. (1994) (81)
- Liquid chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces. (1998) (81)
- MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours (2013) (81)
- Phase II study of weekly gemcitabine in patients with metastatic breast cancer relapsing or failing both an anthracycline and a taxane (2001) (81)
- Development of Multidrug-Resistance Convertors: Sense or Nonsense? (2000) (81)
- Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection. (1997) (80)
- The applicability of mTOR inhibition in solid tumors. (2009) (80)
- Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro (1998) (80)
- Drug Insight: gastrointestinal stromal tumors (GIST)—the solid tumor model for cancer-specific treatment (2008) (79)
- Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug E09. (1994) (79)
- ABCG2 Pharmacogenetics: Ethnic Differences in Allele Frequency and Assessment of Influence on Irinotecan Disposition (2004) (78)
- Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry. (2004) (78)
- Epirubicin in patients with advanced or recurrent adenoid cystic carcinoma of the head and neck: a phase II study of the EORTC Head and Neck Cancer Cooperative Group. (1993) (78)
- Chemotherapy treatment patterns and clinical outcomes in patients with metastatic soft tissue sarcoma. The SArcoma treatment and Burden of Illness in North America and Europe (SABINE) study. (2012) (77)
- A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance. (1991) (76)
- Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors. (1997) (74)
- Renal toxicities of chemotherapy. (2006) (74)
- Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation. (2010) (74)
- Phase II study of bi-weekly administration of paclitaxel and cisplatin in patients with advanced oesophageal cancer (2002) (74)
- Sensitive determination of docetaxel in human plasma by liquid-liquid extraction and reversed-phase high-performance liquid chromatography. (1997) (74)
- Effect of Common CYP3A4 and CYP3A5 Variants on the Pharmacokinetics of the Cytochrome P450 3A Phenotyping Probe Midazolam in Cancer Patients (2005) (73)
- Phase I dose-escalation study of F60008, a novel apoptosis inducer, in patients with advanced solid tumours. (2009) (73)
- The pharmacologic basis of ifosfamide use in adult patients with advanced soft tissue sarcomas. (2007) (73)
- Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group study. (1995) (72)
- Characterisation of the cutaneous pathology in non-small cell lung cancer (NSCLC) patients treated with the EGFR tyrosine kinase inhibitor erlotinib. (2010) (72)
- Simple prognostic model to predict survival in patients with undifferentiated carcinoma of unknown primary site. (1995) (72)
- Cell Cycle/Apoptosis Molecule Expression Correlates with Imatinib Response in Patients with Advanced Gastrointestinal Stromal Tumors (2009) (72)
- Peripheral neuropathy induced by combination chemotherapy of docetaxel and cisplatin. (1997) (72)
- Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells (2010) (71)
- Altered clearance of unbound paclitaxel in elderly patients with metastatic breast cancer. (2003) (71)
- Phase I and pharmacologic study of docetaxel and cisplatin in patients with advanced solid tumors. (1997) (71)
- Docetaxel (Taxotere): single agent activity, development of combination treatment and reducing side-effects. (1995) (71)
- Comparison of ethanol plasma-protein precipitation with plasma ultrafiltration and trichloroacetic acid protein precipitation for the measurement of unbound platinum concentrations (1996) (70)
- Phase I pharmacologic study of oral topotecan and intravenous cisplatin: sequence-dependent hematologic side effects. (2000) (69)
- A phase Ib study of pertuzumab, a recombinant humanised antibody to HER2, and docetaxel in patients with advanced solid tumours (2007) (69)
- Randomized cross-over evaluation of body-surface area-based dosing versus flat-fixed dosing of paclitaxel. (2003) (69)
- Factors involved in prolongation of the terminal disposition phase of SN-38: clinical and experimental studies. (2000) (69)
- Adjuvant therapy in primary GIST: state-of-the-art. (2012) (69)
- Patient selection for oncology phase I trials: a multi-institutional study of prognostic factors. (2012) (68)
- Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors. (1996) (68)
- Pharmacokinetic, metabolic, and pharmacodynamic profiles in a dose-escalating study of irinotecan and cisplatin. (2000) (68)
- A comparison of clinical pharmacodynamics of different administration schedules of oral topotecan (Hycamtin) (1997) (67)
- Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment. (2007) (66)
- Temozolomide in adult patients with advanced soft tissue sarcoma: a phase II study of the EORTC Soft Tissue and Bone Sarcoma Group. (1999) (66)
- Inter-relationships of paclitaxel disposition, infusion duration and Cremophor EL kinetics in cancer patients (2000) (66)
- Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer. (1993) (65)
- Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens. (2003) (65)
- Factors affecting pharmacokinetic variability following doxorubicin and docetaxel-based therapy. (2004) (65)
- A CYP3A4 Phenotype–Based Dosing Algorithm for Individualized Treatment of Irinotecan (2010) (64)
- Phase II and pharmacologic study of topotecan administered as a 21-day continuous infusion to patients with colorectal cancer. (1996) (64)
- Prospective study on the dose relationship of mitomycin C–induced interstitial pneumonitis (1987) (64)
- Five days of oral topotecan (Hycamtin), a phase I and pharmacological study in adult patients with solid tumours. (1998) (63)
- Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel. (2007) (63)
- Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line. (1998) (63)
- Therapeutic Drug Monitoring for the Individualization of Docetaxel Dosing: A Randomized Pharmacokinetic Study (2011) (62)
- Quantitation of Cremophor EL in human plasma samples using a colorimetric dye-binding microassay. (1998) (62)
- Disposition of docetaxel in the presence of P-glycoprotein inhibition by intravenous administration of R101933. (2002) (62)
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- Phase I safety and pharmacokinetic (PK) study of SU014813 (S) in combination with docetaxel (D) in patients (pts) with solid tumors (STs) (2008) (2)
- A phase II study of pirarubicin in patients with advanced recurrent head and neck squamous cell carcinoma (2004) (2)
- Evaluation of CYP3A activity as a predictive covariate for docetaxel clearance (2004) (2)
- Chemotherapy: Adjuvant chemotherapy in older patients with breast cancer (2009) (2)
- [Imatinib, a specific tyrosine-kinase inhibitor, for the treatment of patients with a gastrointestinal stroma cell tumor]. (2003) (2)
- 72 POSTER Phase I, safety, pharmacokinetic and biomarker study of telatinib (BAY 57-9352), an oral VEGFR-2 inhibitor, in a continuous schedule in patients with advanced solid tumors (2006) (2)
- Effect of FNCLCC grade 2 versus grade 3 on survival after neoadjuvant chemotherapy (NAC) plus or minus regional hyperthermia (RHT) in soft tissue sarcomas (STS): An analysis of the EORTC-ESHO Intergroup phase III study. (2011) (1)
- Interaction of platinum compounds with the human organic cation transporter hOCT2 (SLC22A2) (2008) (1)
- Highlights from the EORTC-NCI-AACR 2002 meeting: molecular targets and cancer therapeutics. (2003) (1)
- A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and/or recurrent squamous cell carcinoma of the head and neck. The EORTC Head and Neck Cancer Cooperative Group. (1992) (1)
- Early mortality rates: a tool for phase III trials or for changing standard practice? (2004) (1)
- Predictive Biomarkers and Personalized Medicine CYP 3 A 4 22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity (2013) (1)
- Abstract 1450: MicroRNAs in myxoid/round cell liposarcomas: FUS-CHOP regulated miR-497 and miR-30a target the insulin-like growth factor receptor pathway (2014) (1)
- Effect of genetic variants in CYP2C8, CYP3A4, CYP3A5, and ABCB1 on paclitaxel pharmacokinetics (2005) (1)
- Phase II study of a short course of weekly cisplatin (C) in locally advanced squamous cell carcinoma (SCC) of the head and neck (1993) (1)
- Trial Methodology in Soft Tissue Sarcomas; the ‘One Plus One is Three or Zero’ Phenomenon (2008) (1)
- Type of progression in patients treated with imatinib for advanced gastrointestinal stromal tumor (GIST): A study based on the EORTC-ISG-AGITG trial 62005. (2016) (1)
- 579 Phase I and Pharmacokinetic (PK) Study of Pazopanib in Combination with Two Schedules of Docetaxel (D) in Patients (pts) with Advanced Solid Tumors (2012) (1)
- Mixed response to chemotherapy, a new entity in soft tissue sarcomas. (1995) (1)
- A drug interaction study between ketoconazole and panobinostat (LBH589), an orally active histone deacetylase inhibitor, in patients with advanced cancer. (2009) (1)
- Trial methodology in soft tissue sarcomas; the 'one plus one is three or zero' phenomenon. (2008) (1)
- 961 Phase I study of docetaxel and ifosfamide in patients with advanced solid tumors (1995) (1)
- Prospective evaluation of the pharmacokinetic (PK) and toxicity profile of docetaxel in the elderly. (2004) (1)
- 344 POSTER A phase Ib dose escalation study to evaluate safety and tolerability of the combination of the aminopeptidase inhibitor CHR-2797 and paclitaxel in patients with advanced or treatment refractory tumors (2008) (1)
- Is obtention of partial response (PR) in front line chemotherapy critical to improve outcome of metastatic soft tissue sarcoma (MSTS) patients (pts) (1998) (1)
- 403 Phase I study on RGB-286638, a novel, multi-targeted protein kinase inhibitor, administered as a 1-hour infusion on five consecutive days every 4 weeks in patients (pts) with recurrent or refractory solid tumors (2010) (1)
- Cigarette smoking during irinotecan therapy: Effects on pharmacokinetics and neutropenia (2007) (1)
- [Developments in chemotherapy; cytostatic agents with an increased specificity and other forms of administering cytotoxic antineoplastic agents]. (2001) (1)
- VEGF, sVEGFR-2, bFGF, and IL-8 as biomarkers of the pharmacological activity of BAY 57-9352, an oral VEGFR-2 receptor tyrosine kinase inhibitor, in patients with solid tumors. (2006) (1)
- Phase II study with liposomal muramyl tripeptide phophatidylethanolamine (MTP/PE) in soft tissue sarcomas (STS) (1993) (1)
- Neoadjuvant Chemotherapy Plus Regional Hyperthermia and Long-termOutcomes Among PatientsWith Localized High-Risk Soft Tissue Sarcoma The EORTC 62961-ESHO 95 Randomized Clinical Trial (2017) (1)
- In reply [14] (2005) (1)
- Clinical pharmacokinetics of liposomal lurtotecan (NX211) in whole blood, plasma and urine. (1999) (1)
- Short report: Phase II study of ACNU as first-line treatment in advanced colorectal cancer (1991) (1)
- [Several patients with a metastasised gastrointestinal stroma-cell tumor for whom the tide turned by the introduction of imatinib]. (2003) (1)
- Fifth NCI-EORTC symposium on new drugs in cancer therapy (2004) (1)
- Pharmacokinetics of the multidrug-resistance-converting drug dexniguldipine and its pyridine metabolite M-1 in the plasma, tumor, and renal tissue of tumor-bearing Wag / Rij rats (1997) (1)
- Pharmacokinetics and oral bioavailability of 9-amino-camptothecin PEG1000 capsules (1997) (1)
- How to Define Treatment Success or Failure if Tumors Do Not Shrink (2008) (1)
- Phase II study of mitoxantrone in locally advanced or metastatic adenoid cystic carcinomas (ACC) of the head and neck (1993) (1)
- MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α (2014) (1)
- Are 5HT3 antagonists fully cross-resistant? A pilot experience (1993) (1)
- Dose-response relationship in phase I clinical trials: A European Drug Development Network (EDDN) collaboration study. (2011) (1)
- 7504 ORAL Early progression in patients with high-risk soft tissue sarcomas (STS): A phase III randomized prospective trial (EORTC/ESHO intergroup trial) of neoadjuvant chemotherapy with or without regional hyperthermia (RHT) (2007) (1)
- [The Dutch Health Council report on palliative chemotherapy: possible confusion on ideas]. (2004) (1)
- The use of hematological growth factors to enable dose intensification in chemotherapy for soft tissue sarcomas (1994) (1)
- Gastrointestinal Stromal Tumors (2006) (1)
- 565 Phase I combination study of oral vinorelbine (VRL) and oral cyclophosphamide (CTX) in patients with metastatic breast cancer (MBC) (2003) (0)
- Phase I S tudy o f 3 -Week S chedule o f I rinotecan Combined W ith C isplatin i n P atients W ith A dvanced Solid T umors (2000) (0)
- PIII‐75 (2006) (0)
- Ethical considerations of St. John's wort interaction studies (2017) (0)
- Systematic review on the use of systemic anticancer therapy in renal-impaired gynecological cancer patients. (2008) (0)
- Effects of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: A prospective open-label cross-over drug-interaction study. (2009) (0)
- Contents, Supplement 1, 1996 (1996) (0)
- Abstract 883: Imatinib-induced modulation of gastrointestinal and hepatic membrane transporters in mice. (2013) (0)
- Perspectives of Subtyping in Soft Tissue Sarcomas: The Relevance for Clinical Trial Design (2012) (0)
- 7502 ORAL Assessment of plasma levels of soluble KIT (sKIT) as a potential surrogate marker for TTP in patients (pts) with advanced gastrointestinal stromal tumor (GIST) treated with sunitinib (2007) (0)
- Metabolic disposition of irinotecan in plasma of patients receiving sequential treatment with cisplatin (1999) (0)
- 1256 POSTER Evaluation of Enrollment in Oncology Phase I Clinical Trials (2011) (0)
- Abstracts of papers and posters Clinical Pharmacological Meeting (1993) (0)
- Study of a NewNucleosideAnalogue , OSI-7836 , Using TwoAdministration Schedules in Patientswith Advanced SolidMalignancies (2006) (0)
- Short communication A phase II study of pirarubicin in patients with advanced recurrent head and neck squamous cell carcinoma (1994) (0)
- 38 POSTER Phase I and pharmacological study of KRN951, a potent VEGFR tyrosine kinase inhibitor given in a 4 week on, 2 week off schedule in patients with advanced solid tumors (2006) (0)
- Prophylactic treatment of irinotecan-induced diarrhea with neomycin (a randomized, placebo-controlled, double-blind study). (2006) (0)
- Phase II study of a short course of weekly cisplatin (C) combined with oral etoposide (E) in pleural mesothelioma (1993) (0)
- The multidisciplinary approach to treatment of soft tissue sarcomas. (1992) (0)
- Principles and Examples of Cancer (Cell) Specific Therapies (2009) (0)
- miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway (2015) (0)
- Oral ZD9331, a non-polyglutamated thymidylate synthase (TS) inhibitor: a phase I and pharmacologic study (1999) (0)
- Abstract A189: Influence of smoking on the pharmacology of taxane therapy. (2011) (0)
- The absence of influence of acetylsalicylic acid (ASA) on the transient decrease in platelet counts observed after infusion of bleomycin and vinblastine. (1985) (0)
- A phase II study of high dose ifosfamide in metastatic colorectal cancer. (1989) (0)
- A phase I study of the combination of daily oral sunitinib with intravenous ifosfamide in patients with advanced solid malignancies (2009) (0)
- Adjuvant treatment of gastrointestinal stromal tumor: the proof, the pro, and the practice. (2012) (0)
- Mitomycin C. (1988) (0)
- Abstract ED02-02: Phasing out phase III trials: How much evidence do we need if the target is clearly hit? (2011) (0)
- Pharmacokinetic, M etabolic, a nd P harmacodynamic Profiles i n a D ose-Escalating S tudy o f Irinotecan a nd C isplatin (2000) (0)
- Body-Surface A rea-Based D osing D oes N ot I ncrease Accuracy o f P redicting C isplatin E xposure (2013) (0)
- Phase I P harmacologic S tudy o f O ral T opotecan a nd Intravenous C isplatin: S equence-Depende nt H ematologic Side E ffects (2000) (0)
- Mitomycin C (1987) (0)
- Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent administered as an infusion over 24 h every 21 days in patients with solid tumors (2007) (0)
- Feasibility study of high dose ifosfamide (I) plus cisplatin (C) combined with rh-GCSF every 2 weeks in advanced solid tumors (1993) (0)
- Impact o f B ody-Size M easures o n I rinotecan C learance: Alternative D osing R ecommendations (2002) (0)
- Mitomycin C, prototype of a bioreductive alkylating agent (1991) (0)
- Phase I and Pharmacology Studies (2004) (0)
- Growth modulation index (GMI) as a metric of clinical benefit assessment among advanced soft tissue sarcoma (ASTS) patients receiving trabectedin as salvage therapy. (2012) (0)
- Target KIT and ETV1 in gastrointestinal stromal tumors (GIST) (2012) (0)
- Mitomycin-C (1991) (0)
- Radioimmunodetection and Radioimmunotherapy in Myosarcoma (1989) (0)
- Phase I a nd P harmacokinetic S tudy o f t he O ral F arnesyl Transferase I nhibitor S CH 6 6336 G iven T wice D aily t o Patients W ith A dvanced S olid T umors (2001) (0)
- Nursing care adaptations during clinical trials with weekly high‐dose cisplatin: evaluation of a process plan (1993) (0)
- E¡ects of impaired renal function on the pharmacokinetics and toxicity of i.v. ZD9331, a novel non-polyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors (2002) (0)
- Reply: Granisetron vs ondansetron: is it a question of duration of 5-HT3 receptor blockade? (2002) (0)
- Capecitabine, a n O ral F luoropyrimidine C arbamate W ith Substantial A ctivity i n A dvanced C olorectal C ancer: Results o f a R andomized P hase I I S tudy (2000) (0)
- Genetic predisposition to oral absorption of imatinib: Correlation of a variant allele in ABCG2 with transport activity (2005) (0)
- Irinotecan Pathway Genotype Analysis to Predict Pharmacokinetics 1 (2003) (0)
- Comparative P harmacokinetics o f U nbound P aclitaxel During 1 - a nd 3 -Hour I nfusions (2002) (0)
- A phase II study of Gefitinib for patients with HER-1 expressing advanced synovial sarcoma refractory to doxorubicin-based chemotherapy. (2008) (0)
- FREE PAPERS (Oral Presentations) (2007) (0)
- Early response to neoadjuvant chemotherapy (NAC) in combination with regional hyperthermia (RHT) to predict long-term survival for adult-type high-risk soft tissue sarcoma (HR-STS): Results of the EORTC-ESHO intergroup phase III study. (2012) (0)
- Phase I a nd P harmacologic S tudy o f O ral ( PEG-1000) 9-Aminocamptothecin i n A dult P atients W ith S olid T umors (1999) (0)
- Correction: A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation. (2022) (0)
- Phase I study on EO9 given every 3 weeks (1993) (0)
- Clinical Management of Soft Tissue Sarcomas (2011) (0)
- Primary care in cancer control (2015) (0)
- Mitomycin C. (1990) (0)
- Abstract A5: microRNA response to hypoxic stress in soft tissue sarcoma cells (2011) (0)
- Confusion caused by similarity in manuscript titles. (2003) (0)
- Abstract 4952: Functional characterization of microRNAs associated with the response to cisplatin of ovarian cancer cells (2011) (0)
- 394 A phase I dose escalation and pharmacological study of the novel class I selective histone deacetylase inhibitor CHR-3996, in patients with advanced or treatment refractory solid tumours (2010) (0)
- A phase I dose escalation study of BIBW 2992, an irreversible tyrosine kinase inhibitor of epidermal growth factor receptor 1 (EGFR-1) and 2 (HER 2) in a 2 week on 2 week off schedule in patients with advanced solid tumors. (2005) (0)
- First Clinical Experience with Cytorhodin S — The First Compound of a New Class of Anthracyclines (1989) (0)
- Phase II study of Topotecan (TC) in patients (pts) with pretreated small-cell lung cancer (SCLC) (1994) (0)
- Absence of interaction between furosemide and mitomycin C (2004) (0)
- Cancer Therapy (1989) (0)
- Phase I and pharmacoklnetic (PK) study of irinotecan (CPT-11) and cisplatin in patients with solid tumors: Preliminary results (1997) (0)
- 275 Taxanes in angiosarcomas (2009) (0)
- EDATREXATE VERSUS METHOTREXATE IN HEAD AND NECK SCC 1651 (2019) (0)
- 654 Predictive value of a dextromethorphan phenotyping test for endoxifen exposure (2010) (0)
- Phase II trials of drug combinations: fairytales or fact? (2005) (0)
- A randomized Bayesian phase 1 design combining an MPS-1 inhibitor with paclitaxel: A strategy to improve determination of the incremental toxicity of a novel compound over a known backbone therapy. (2018) (0)
- Early Clinical Trials with Cytotoxic Agents (2011) (0)
- Prediction of early death among patients (pts) enrolled in phase I trials: Development and validation of a new model based on platelet count and albumin level. (2012) (0)
- Reply to F.L. Opdam et al (2012) (0)
- Abstracts of papers clinical pharmacological meeting (2005) (0)
- 500PD NEW DIAGNOSTIC TECHNIQUES IN EARLY DIAGNOSIS OF MELANOMA IN SITU (2006) (0)
- 983 New drugs for the turn of the century (1995) (0)
- Weekly high dose cisplatin (P) and daily oral vepesid (VP): A highly active salvage regimen for progressive or recurrent ovarian cancer after platinum therapy (1997) (0)
- Evaluation of body‐surface area based dosing of cisplatin in patients with extreme BSA values (2005) (0)
- The EORTC and drug development. European Organisation for Research and Treatment of Cancer. (2002) (0)
- relationship ofcisplatin invitro: simulation of ani.v. bolus and3hand20hinfusion (1994) (0)
- Pharmacokinetic-pharmacodynamic models for topotecan-induced neutropenia. (2004) (0)
- Abstract 949: miR-634 restores drug sensitivity in tumor cells derived from patients with terminal drug-resistant ovarian cancer. (2013) (0)
- Optimised Sample Preparation for Measurement of Cisplatin-DNA Adducts in White Blood Cells (1995) (0)
- Influence of drug exposure and genetic variation on paclitaxel-induced neurotoxicity (2012) (0)
- RAS-oncogene interacting agents (1999) (0)
- An international multidisciplinary approach to the management of advanced colorectal cancer (First of two parts) (Reprinted from Eur J Surg Oncol, vol 23, Suppl A, August 1997) (1998) (0)
- Introduction: Recent Topics in the Clinical Pharmacology of Taxanes that Might Change Future Perspectives (2001) (0)
- Pharmaceutical industry, investigators and institutions: Partners or tools? (2005) (0)
- Phase I and Pharmacokinetic Study of the Polyamine Synthesis Inhibitor SAM 486 A in Combination with 5-Fluorouracil / Leucovorin in Metastatic Colorectal Cancer (2004) (0)
- Volume Contents (2004) (0)
- Role of CYP3A4 phenotyping by midazolam clearance in predicting irinotecan pharmacokinetics. (2004) (0)
- P3-16-08: A Phase 2, Randomized Open-Label Study of Iniparib, Administered Either Weekly or Twice-Weekly in Combination with Gemcitabine Plus Carboplatin in Patients with mTNBC. (2011) (0)
- Taxanes in angiosarcomas (2009) (0)
- P2-17-04: Induction of Tamoxifen Metabolism by Rifampicin: A Worrying Drug-Drug Interaction. (2011) (0)
- PII‐20 (2006) (0)
- Letter (2007) (0)
- Docetaxel (taxotere) in adavanced malignant melanoma :a phase II study of the EORTC eraly clinical trials group (1994) (0)
- Pharmacogenetic influence of OATP1B1 variants *1b and *15 on irinotecan disposition in Asian and Caucasian cancer patients. (2006) (0)
- Trial design for cancer (cell)-specific anticancer therapies (2007) (0)
- Biological and clinical aspects of drug-resistance and -sensitivity of malignancies (1998) (0)
- 382 Influence of rosuvastatin on the pharmacokinetics of imatinib: a cross-over study (2010) (0)
- Effect of cigarette smoking on pharmacokinetics, safety and efficacy of imatinib: a study based on data of the Soft Tissue and Bone Sarcoma Group of the EORTC (2009) (0)
- Short communication Determination of 5-fluorouracil in microvolumes of human plasma q by solvent extraction and high-performance liquid chromatography (1999) (0)
- Possible lack of full cross-resistance between 5HT3 antagonists, a pilot experience (1993) (0)
- Interactionof Cisplatinwith the HumanOrganic CationTransporter 2 (2008) (0)
- What is the role of dose-dense therapy? (2005) (0)
- [Vitamin A derivatives: potential prevention and therapy of solid tumors]. (1993) (0)
- Limited potential of hepatic arterial infusion of irinotecan. (2004) (0)
- [Microangiopathic hemolytic anemia and metastasized carcinoma]. (1986) (0)
- Possible lack of full cross-resistance of 5HT3 antagonists; a pilot study (1995) (0)
- Phase II study of ACNU as first-line treatment in advanced colorectal cancer. (1991) (0)
- Abstracts of Papers Presented at the Connective Tissue Oncology Society 4th Annual Scientific Meeting, 12–14 November 1998, Vancouver, BC, Canada (1999) (0)
- Long-term responders and survivors on pazopanib for soft tissue sarcomas (STS): Subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072. (2013) (0)
- Randomized C ross-Over E valuation o f B ody-Surface Area-Based D osing V ersus F lat-Fixed D osing o f P aclitaxel (2003) (0)
- Neo-adjuvant chemotherapy in adult soft tissue sarcoma. EORTC Protocol 62847 (1997) (0)
- Effect of smoking on imatinib pharmacokinetics (2007) (0)
- Epirubicin is not a substitute for Doxorubicine in advanced soft tissue sarcomas. Final data from the EORTC Soft Tissue and Bone Sarcoma Group (1998) (0)
- New targets in oncology drug development. (2005) (0)
- Predictive and mechanistic factors of tyrosine kinase inhibitor (TKI)-induced macrocytosis. (2010) (0)
- The importance of quality and accuracy in the conduct of clinical trials: EORTC quality assurance measures (1992) (0)
- Pharmacokinetic-pharmacodynamic models for topotecan-induced neutropenia (2004) (0)
- Abstract ED01-01: Successes and failures of targeted drug development in adult and pediatric sarcomas (2019) (0)
- 7 Assessing target functionality for drug and patient tailoring: a clinical perspective (2010) (0)
- Mechanism-Based P harmacokinetic M odel f or P aclitaxel (2001) (0)
- Abstract CN04-02: Phase I trials: Limits and limitations in proof of concept (2009) (0)
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