John W. Daly
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(Suggest an Edit or Addition)John W. Daly's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nomenclature and classification of purinoceptors. (1994) (1631)
- Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. (1981) (1546)
- Arene oxides: a new aspect of drug metabolism. (1974) (972)
- Adenosine receptors and behavioral actions of methylxanthines. (1981) (676)
- Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein. (1981) (657)
- Adenosine receptors: targets for future drugs. (1982) (596)
- Alkaloids from amphibian skin: a tabulation of over eight-hundred compounds. (2005) (566)
- Adenosine receptors in the central nervous system: relationship to the central actions of methylxanthines. (1981) (528)
- Adenosine receptors in brain membranes: binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine. (1980) (489)
- Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an ecuadoran poison frog (1992) (448)
- A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN (1969) (448)
- Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. (1967) (443)
- Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate- generating systems, receptors, and enzymes (1985) (400)
- 1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. (1970) (395)
- Forskolin: a unique diterpene activator of cyclic AMP-generating systems. (1981) (390)
- A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide. (1971) (388)
- Epibatidine, a potent analgetic and nicotinic agonist. (1994) (388)
- Further classification of skin alkaloids from neotropical poison frogs (Dendrobatidae), with a general survey of toxic/noxious substances in the amphibia. (1987) (359)
- A rapid spectrophotometric assay of mono-amine oxidase based on the rate of disappearance of kynuramine. (1960) (354)
- Alkylxanthines: inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity. (1979) (301)
- Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors. (1971) (298)
- Cyclic Nucleotides in the Nervous System (1977) (288)
- Adenosine receptor ligands: differences with acute versus chronic treatment. (1996) (266)
- Forskolin, cyclic AMP and cellular physiology (1983) (250)
- The chemistry of poisons in amphibian skin. (1995) (238)
- Forskolin: its biological and chemical properties. (1986) (237)
- Caffeine--an atypical drug of dependence. (1998) (234)
- 4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain. (1976) (223)
- Thirty years of discovering arthropod alkaloids in amphibian skin. (1998) (221)
- 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. (1985) (220)
- Role of the arene oxide-oxepin system in the metabolism of aromatic substrates: I. In vitro conversion of benzene oxide to a premercapturic acid and a dihydrodiol (1968) (214)
- Toxicity of Panamanian Poison Frogs (Dendrobates): Some Biological and Chemical Aspects (1967) (214)
- Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines (1983) (204)
- Activation of Cyclic AMP‐Generating Systems in Brain Membranes and Slices by the Diterpene Forskolin: Augmentation of Receptor‐Mediated Responses (1982) (196)
- The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. (1968) (195)
- Homobatrachotoxin in the genus Pitohui: chemical defense in birds? (1992) (194)
- Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors. (1988) (191)
- Batrachotoxin: Chemistry and Pharmacology (1971) (182)
- Nicotinic Agonists, Antagonists, and Modulators From Natural Sources (2005) (179)
- 8‐(3‐Chlorostyryl)caffeine (CSC) is a selective A2‐adenosine antagonist in vitro and in vivo (1993) (176)
- Substrates and inhibitors of dopamine-β-oxidase (1962) (164)
- Widespread occurrence in frogs and toads of skin compounds interacting with the ouabain site of Na+, K+-ATPase. (1980) (163)
- Binding of batrachotoxinin A 20-alpha-benzoate to a receptor site associated with sodium channels in synaptic nerve ending particles. (1981) (155)
- Formicine ants: An arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs. (2004) (154)
- Stimulated formation of adenosine 3',5'-cyclic phosphate in cerebral cortex: synergism between electrical activity and biogenic amines. (1970) (154)
- Cis-1,2-dihydroxy-1,2-dihydronaphthalene: a bacterial metabolite from naphthalene. (1971) (150)
- Oribatid mites as a major dietary source for alkaloids in poison frogs (2007) (149)
- Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions. (1986) (149)
- Classification of skin alkaloids from neotropical poison-dart frogs (Dendrobatidae). (1978) (147)
- Adenosine-dependent formation of cyclic AMP in brain slices. (1976) (147)
- Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes. (1972) (147)
- Effect of gangliosides on adenylate cyclase activity in rat cerebral cortical membranes. (1979) (147)
- Catechol-O-methyltransferase. II. A new class of inhibitors of catechol-o-methyltransferase; 3,5-dihydroxy-4-methoxybenzoic acid and related compounds. (1970) (145)
- Dart-poison frogs. (1983) (141)
- Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine. (1974) (141)
- ACCUMULATION OF CYCLIC ADENOSINE 3′, 5′‐MONOPHOSPHATE IN CEREBRAL CORTICAL SLICES FROM RAT AND MOUSE: STIMULATORY EFFECT OF α‐ AND β‐ADRENERGIC AGENTS AND ADENOSINE (1973) (140)
- An uptake system for dietary alkaloids in poison frogs (Dendrobatidae). (1994) (139)
- 3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. (1988) (139)
- Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts. (1994) (136)
- Melyrid beetles (Choresine): a putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds. (2004) (135)
- Maitotoxin: a unique pharmacological tool for research on calcium-dependent mechanisms. (1990) (134)
- Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives. (1983) (133)
- The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex. (1985) (131)
- Deuterium isotope effects during formation of phenols by hepatic monoxygenases. Evidence for an alternative to arene oxide pathway. (1975) (129)
- Coumarins and carbazoles from Clausena excavata exhibited antimycobacterial and antifungal activities. (2003) (129)
- Fluoronorepinephrines: specific agonists for the activation of alpha and beta adrenergic-sensitive cyclic AMP-generating systems in brain slices. (1980) (126)
- A dangerously toxic new frog (Phyllobates) used by Emberá Indians of western Colombia, with discussion of blowgun fabrication and dart poisoning. Bulletin of the AMNH ; v. 161, article 2 (1978) (125)
- Liver microsomal expoxide hydrase. Solubilization, purification, and characterization. (1975) (124)
- Histrionicotoxins: roentgen-ray analysis of the novel allenic and acetylenie spiroalkaloids isolated from a Colombian frog, Dendrobates histrionicus. (1971) (122)
- Batrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldi) from New Guinea. (2000) (121)
- 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists. (2002) (119)
- A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase. (1992) (119)
- A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor (1986) (119)
- Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase. (1973) (118)
- Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I. Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine triphosphate and from radioactive adenosine triphosphate formed during a prior incubation with radioactive adenine. (1973) (118)
- Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. (1986) (118)
- Inhibition of aggregation and stimulation of cyclic AMP generation in intact human platelets by the diterpene forskolin. (1982) (117)
- The structure of batrachotoxin, a steroidal alkaloid from the Colombian arrow poison frog, Phyllobates aurotaenia, and partial synthesis of batrachotoxin and its analogs and homologs. (1969) (116)
- Role of the arene oxide-oxepin system in the metabolism of aromatic substrates. IV. Stereochemical considerations of dihydrodiol formation and dehyrogenation (1970) (115)
- A role for central A3‐adenosine receptors (1993) (113)
- Frog secretions and hunting magic in the upper Amazon: identification of a peptide that interacts with an adenosine receptor. (1992) (113)
- Dietary source for skin alkaloids of poison frogs (Dendrobatidae)? (1994) (109)
- Morphology of the granular secretory glands in skin of poison-dart frogs (Dendrobatidae). (1979) (109)
- A new class of tyrosine hydroxylase inhibitors and a simple assay of inhibition in vivo. (1967) (108)
- Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism. (1991) (107)
- The dextro and levorotatory isomers of N-phenylisopropyladenosine: stereospecific effects on cyclic AMP-formation and evoked synaptic responses in brain slices. (1979) (107)
- Spatial and temporal patterns of alkaloid variation in the poison frog Oophaga pumilio in Costa Rica and Panama over 30 years. (2007) (106)
- Batrachotoxin-induced depolarization and [3H]batrachotoxinin-a 20 alpha-benzoate binding in a vesicular preparation from guinea pig cerebral cortex. (1983) (106)
- Preliminary evaluation of skin toxins and vocalizations in taxonomic and evolutionary studies of poison-dart frogs (Dendrobatidae). Bulletin of the AMNH ; v. 157, article 3 (1976) (106)
- Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions. (1973) (106)
- Alkaloids from frog skin: the discovery of epibatidine and the potential for developing novel non-opioid analgesics. (2000) (106)
- Cyclic AMP-generating systems: regional differences in activation by adrenergic receptors in rat brain (1981) (103)
- Binding of [3H]forskolin to rat brain membranes. (1984) (103)
- Physiology and pharmacology of adenosine derivatives (1983) (103)
- Bioactive alkaloids of frog skin: Combinatorial bioprospecting reveals that pumiliotoxins have an arthropod source (2002) (100)
- The combined use of α-methyltyrosine and threo-dihydroxyphenylserine—selective reduction of dopamine levels in the central nervous system (1968) (99)
- Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. (2003) (99)
- Gephyrotoxins, histrionicotoxins and pumiliotoxins from the neotropical frog Dendrobates histrionicus. (1977) (99)
- Dynamic aspects of enzymatic O-methylation and -demethylation of catechols in vitro and in vivo. (1960) (99)
- Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain (1993) (99)
- Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes. (1973) (98)
- Catechol O-methyltransferase. IV. Factors affecting m- and p-methylation of substituted catechols. (1972) (97)
- Levels of batrachotoxin and lack of sensitivity to its action in poison-dart frogs (Phyllobates). (1980) (97)
- Arene oxides as intermediates in the oxidative metabolism of aromatic compounds. Isomerization of methyl-substituted arene oxides. (1972) (95)
- Solubilization, purification, and properties of a hepatic epoxide hydrase. (1971) (94)
- Guanosine 5'-(beta, gamma-imido)triphosphate inhibition of forskolin-activated adenylate cyclase is mediated by the putative inhibitory guanine nucleotide regulatory protein. (1982) (94)
- Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors. (1986) (94)
- Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines. (1993) (93)
- Binding of alpha-and beta-adrenergic ligands to cerebral cortical membranes: effect of 6-hydroxydopamine treatment and relationship to the responsiveness of cyclic amp-generating systems in two rat strains. (1978) (92)
- An activator of protein kinase C (phorbol‐12‐myristate‐13‐acetate) augments 2‐chloroadenosine‐elicited accumulation of cyclic AMP in guinea pig cerebral cortical particulate preparations (1985) (92)
- Forskolin, adenylate cyclase, and cell physiology: an overview. (1984) (91)
- [3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. (1985) (91)
- Locomotor activity in mice during chronic treatment with caffeine and withdrawal (1993) (91)
- Oxygen-dependent reaction of 6-hydroxydopamine, 5,6-dihydroxytryptamine, and related compounds with proteins in vitro: a model for cytotoxicity. (1976) (90)
- A study of the irreversible cholinesterase inhibitor, diisopropylfluorophosphate, on time course of end-plate currents in frog sartorius muscle. (1974) (90)
- Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes. (1971) (90)
- Membrane potential fluorescence: A rapid and highly sensitive assay for nicotinic receptor channel function (2003) (90)
- Accumulations of Cyclic AMP in Adenine‐Labeled Cell‐free Preparations from Guinea Pig Cerebral Cortex: Role of α‐Adrenergic and H1‐Histaminergic Receptors (1980) (90)
- Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes. I. Influence of ring substitutents. (1968) (88)
- Arene oxides and the NIH shift: The metabolism, toxicity and carcinogenicity of aromatic compounds (1972) (87)
- Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 2. Effects of depolarizing agents, membrane stabilizers, phosphodiesterase inhibitors, and adenosine analogs. (1972) (87)
- Ernest Guenther award in chemistry of natural products. Amphibian skin: a remarkable source of biologically active arthropod alkaloids. (2003) (84)
- The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker. (2004) (83)
- Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor. (1977) (83)
- Enzymatic p-O-Methylation by Catechol O-Methyl Transferase (1959) (82)
- Injury to the ureter during gynecologic surgical procedures. (1988) (82)
- Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors. (1993) (81)
- Alkaloids from dendrobatid frogs: structures of two omega-hydroxy congeners of 3-butyl-5-propylindolizidine and occurrence of 2,5-disubstituted pyrrolidines and a 2,6-disubstituted piperidine. (1986) (81)
- Species differences in structure‐activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors (1986) (80)
- Formation of cyclic adenosine 3',5'-monophosphate from adenosine in brain slices. (1970) (80)
- Alkaloids from a panamanian poison frog, Dendrobates speciosus: identification of pumiliotoxin-A and allopumiliotoxin class alkaloids, 3,5-disubstituted indolizidines, 5-substituted 8-methylindolizidines, and a 2-methyl-6-nonyl-4-hydroxypiperidine. (1988) (80)
- Arthropod–Frog Connection: Decahydroquinoline and Pyrrolizidine Alkaloids Common to Microsympatric Myrmicine Ants and Dendrobatid Frogs (2004) (79)
- The nature of receptors regulating the formation of cyclic AMP in brain tissue. (1976) (79)
- Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. (1985) (79)
- Geographic and Seasonal Variation in Alkaloid-Based Chemical Defenses of Dendrobates pumilio from Bocas del Toro, Panama (2006) (79)
- Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. (1986) (78)
- Cyclic adenosine 3',5'-monophosphate formation in brain slices: stimulation by batrachotoxin, ouabain, veratridine, and potassium ions. (1970) (78)
- First occurrence of tetrodotoxin in a dendrobatid frog (Colostethus inguinalis), with further reports for the bufonid genus Atelopus. (1994) (78)
- Further Alkaloids Common to Ants and Frogs: Decahydroquinolines and a Quinolizidine (1999) (78)
- ADENOSINE RECEPTORS: TARGETS FOR FUTURE DRUGS (1982) (77)
- Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine. (1997) (76)
- A new class of indolizidine alkaloids from the poison frog, Dendrobates tricolor. X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane (1980) (76)
- The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. II. Synthesis of 3,4-toluene-4-2H oxide and subsequent "NIH shift" to 4-hydroxytoluene-3-2H. (1968) (75)
- Alkaloids in Madagascan frogs (Mantella): pumiliotoxins, indolizidines, quinolizidines, and pyrrolizidines. (1993) (74)
- Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions. (1989) (73)
- Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine. (1985) (73)
- Activation of rat cerebral cortical 3',5'-cyclic nucleotide phosphodiesterase activity by gangliosides. (1980) (73)
- [3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors. (1986) (72)
- Nuclear Magnetic Resonance Spectra of Indoles (1960) (71)
- New classes of amidine, indolizidine and quinolizidine alkaloids from a poison-frog, dendrobates pumilio (dendrobatidae) (1987) (70)
- Regulation of cyclic AMP formation in brain tissue by alpha-adrenergic receptors: requisite intermediacy of prostaglandins of the E series. (1980) (70)
- Effect of histrionicotoxin on the ionic conductance modulator of the cholinergic receptor: a quantitative analysis of the end-plate current. (1974) (70)
- Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. (1981) (70)
- Caffeine analogs: structure-activity relationships at adenosine receptors. (1991) (69)
- The production of meta-chlorotyrosine from para-chlorophenylalanine by phenylalanine hydroxylase (1966) (69)
- Evidence for biosynthesis of pseudophrynamine alkaloids by an Australian myobatrachid frog (pseudophryne) and for sequestration of dietary pumiliotoxins. (2002) (69)
- Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry. (1992) (68)
- Steroidal alkaloids (batrachotoxins and 4β-hydroxybatrachotoxins), “indole alkaloids” (calycanthine and chimonanthine) and a piperidinyldipyridin (1983) (68)
- Occurrence of skin alkaloids in non-dendrobatid frogs from Brazil (Bufonidae), Australia (Myobatrachidae) and Madagascar (Mantellinae). (1984) (68)
- Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. (2002) (68)
- Allenic and acetylenic spiropiperidine alkaloids from the neotropical frog, Dendrobates histrionicus. (1974) (67)
- The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines. (1966) (67)
- Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates (2003) (67)
- Batrachotoxin. The active principle of the Colombian arrow poison frog, Phyllobates bicolor. (1965) (66)
- Chronic effects of a monoamine oxidase-inhibiting antidepressant: decreases in functional alpha-adrenergic autoreceptors precede the decrease in norepinephrine-stimulated cyclic adenosine 3': 5'- monophosphate systems in rat brain (1982) (65)
- Formation of inositol phosphates in synaptoneurosomes of guinea pig brain: stimulatory effects of receptor agonists, sodium channel agents and sodium and calcium ionophores (1988) (65)
- Metobolism of chlorobenzene with hepatic microsomes and solubilized cytochrome P-450 systems. (1975) (65)
- Accumulation of adenosine cyclic 3',5'-monophosphate in rat cerebral cortical slices. Stimulatory effect of alpha and beta adrenergic agents after treatment with 6-hydroxydopamine, 2,3,5-trihydroxyphenethylamine, and dihydroxytryptamines. (1973) (65)
- Adenosine receptors: development of selective agonists and antagonists. (1987) (64)
- The structure of batrachotoxinin A, a novel steroidal alkaloid from the Colombian arrow poison frog, Phyllobates aurotaenia. (1968) (64)
- The role of calcium ions in accumulation of cyclic adenosine monophosphate elicited by alpha and beta adrenergic agonists in rat brain slices. (1977) (64)
- Chronic Effects of Xanthines on Levels of Central Receptors in Mice (1999) (63)
- Actions of the histrionicotoxins at the ion channel of the nicotinic acetylcholine receptor and at the voltage-sensitive ion channels of muscle membranes. (1982) (63)
- Effect of depolarizing agents on accumulation of cyclic adenosine 3',5'-monophosphate in cerebral cortical slices. (1972) (62)
- Discovery of a defensively malodorous and nocturnal frog in the family Dendrobatidae : phylogenetic significance of a new genus and species from the Venezuelan Andes. American Museum novitates ; no. 3002 (1991) (62)
- Rearrangement of (1- 2 H)- and (2- 2 H)naphthalene 1,2-oxides to 1-naphthol. Mechanism of the NIH shift. (1972) (61)
- Stimulation of phosphoinositide breakdown in brain synaptoneurosomes by agents that activate sodium influx: antagonism by tetrodotoxin, saxitoxin, and cadmium. (1987) (60)
- Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. II. The role of phosphodiesterase activity in the regulation of levels of cyclic adenosine 3',5'-monophosphate. (1973) (60)
- Cyclic adenosine 3',5'monophosphate role in the physiology and pharmacology of the central nervous system. (1975) (59)
- Synthesis and biological properties of 2-, 5-, and 6-fluoronorepinephrines. (1979) (59)
- Norepinephrine-Sensitive Adenylate Cyclases in Rat Brain: Relation to Behavior and Tyrosine Hydroxylase (1974) (59)
- Histamine‐elicited accumulations of cyclic adenosine 3′,5′‐monophosphate in guinea‐pig brain slices: Effect of H1‐ and H2‐antagonists (1975) (59)
- Marine toxins and nonmarine toxins: convergence or symbiotic organisms? (2004) (59)
- Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relationships of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants. (1972) (59)
- Biologically active substances from amphibians: preliminary studies on anurans from twenty-one genera of Thailand. (2004) (58)
- Regulation of adenosine cyclic 3',5'-phosphate formation in cerebral cortical slices. Interaction among norepinephrine, histamine, serotonin. (1971) (58)
- Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations. (1978) (58)
- A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. (1972) (58)
- Chapter One - Alkaloids from Amphibian Skins (1999) (57)
- Accumulation of adenosine 3':5'-cyclic monophosphate in clonal glial cells: labeling of intracellular adenine nucleotides with radioactive adenine. (1972) (57)
- Norepinephrine-Sensitive Systems Generating Adenosine 3',5'-Monophosphate: Increased Responses in Cerebral Cortical Slices from Reserpine-Treated Rats (1974) (57)
- Absence of skin alkaloids in captive-raised Madagascan mantelline frogs (Mantella) and sequestration of dietary alkaloids. (1997) (57)
- Enzymatic conversion of 5-tritiotryptophan to 4-tritio-5-hydroxytryptophan (1966) (57)
- Patients with Malignant Hyperthermia Demonstrate an Altered Calcium Control Mechanism in B Lymphocytes (2002) (56)
- Identification of 3,4-Dimethoxyphenethylamine from Schizophrenic Urine by Mass Spectrometry (1967) (56)
- Variability in alkaloid profiles in neotropical poison frogs (Dendrobatidae): genetic versus environmental determinants. (1992) (56)
- Alkaloids from dendrobatid poison frogs: trans-decahydroquinolines and indolizidines (1986) (56)
- Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. 3. Formation, degradation, and reformation of cyclic adenosine 3',5'-monophosphate during sequential stimulations by biogenic amines and adenosine. (1973) (55)
- Aryl hydrocarbon hydroxylase, epoxide hydrase, and 7,12-dimethylbenz(a)anthracene-produced skin tumorigenesis in the mouse. (1972) (55)
- Use of dansyl derivatives and mass spectrometry for identification of biogenic amines. (1968) (55)
- Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors. (1987) (55)
- Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. (1985) (54)
- Alkaloids in Bufonid Toads (Melanophryniscus): Temporal and Geographic Determinants for Two Argentinian Species (2007) (54)
- Accumulations of inositol phosphates and cyclic AMP in brain slices: synergistic interactions of histamine and 2-chloroadenosine. (1986) (54)
- INTERRELATIONSHIPS AMONG THE LEVELS OF ATP, ADENOSINE AND CYCLIC AMP IN INCUBATED SLICES OF GUINEA‐PIG CEREBRAL CORTEX: EFFECTS OF DEPOLARIZING AGENTS, PSYCHOTROPIC DRUGS AND METABOLIC INHIBITORS (1974) (53)
- Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. (1968) (53)
- The protein kinase C activator phorbol‐12‐myristate‐13‐acetate enhances cyclic AMP accumulation in pheochromocytoma cells (1986) (52)
- Bioassay-guided isolation of epiquinamide, a novel quinolizidine alkaloid and nicotinic agonist from an Ecuadoran poison frog, Epipedobates tricolor. (2003) (52)
- Characterization of the locomotor depression produced by an A2‐selective adenosine agonist (1990) (52)
- Venom chemistry of the ant Myrmicaria melanogaster from Brunei. (2007) (52)
- Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors. (1988) (52)
- The role of adenosine receptors in the central action of caffeine. (2020) (51)
- Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells. (1992) (51)
- Adenosine receptor interactions and anxiolytics (1983) (51)
- Migration of substituents during Hydroxylation of aromatic substrates (NIH shift). Oxidations with peroxytrifluoroacetic acid. (1971) (51)
- Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers. (1995) (50)
- Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle (1975) (50)
- Pharmacological activity of alkaloids from poison-dart frogs (Dendrobatidae). (1978) (50)
- Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine. (1975) (50)
- An electrophysiological study of the effects of D-tubocurarine, atropine, and alpha-bungarotoxin on the cholinergic receptor in innervated and chronically denervated mammalian skeletal muscles. (1974) (50)
- Purines. VI. The Preparation of Certain 6-Substituted-and 6,9-Disubstituted Purines (1956) (49)
- Molecular probes for extracellular adenosine receptors. (1987) (49)
- The antinociceptive effect of intrathecally administered adenosine analogs in mice correlates with the affinity for the A1-adenosine receptor (1991) (49)
- Role of Cyclic Nucleotides in the Nervous System (1975) (49)
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- INTRAMOLECULAR MIGRATION OF TRITIUM AND DEUTERIUM DURING NONENZYMATIC AROMATIC HYDROXYLATION. (1967) (48)
- Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine. (1966) (48)
- A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine. (1986) (48)
- Anti‐HIV‐1 limonoid: first isolation from Clausena excavata (2003) (48)
- Chapter 39 – Chemistry and Pharmacology of Frog Venoms (1971) (47)
- Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase. (1992) (47)
- A common pumiliotoxin from poison frogs exhibits enantioselective toxicity against mosquitoes (2006) (47)
- Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. (1986) (47)
- The formation, degradation, and function of cyclic nucleotides in the nervous system. (1977) (47)
- A new class of alkaloids from a dendrobatid poison frog: a structure for alkaloid 251F. (1992) (47)
- Highly stereoselective construction of trans(2,3)-cis(2,6)-trisubstituted piperidines: An application to the chiral synthesis of Dendrobates alkaloids (1997) (47)
- Membrane Potentials in Cell‐free Preparations from Guinea Pig Cerebral Cortex: Effect of Depolarizing Agents and Cyclic Nucleotides (1980) (46)
- Caffeine: a model drug of abuse. (1990) (46)
- Batrachotoxin, a Selective Probe for Channels Modulating Sodium Conductances in Electrogenic Membranes (1977) (46)
- An arboreal poison frog (Dendrobates) from western Panama. (1984) (46)
- Stimulation of adenosine 3',5'-monophosphate formation in rat cerebral cortical slices by methoxamine: interaction with an alpha adrenergic receptor. (1975) (46)
- Ibogaine: a potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors. (1997) (46)
- Selective stimulation of Ca2+ flux in cells by maitotoxin. (1992) (45)
- Multiple effects of caffeine on Ca2+ release and influx in human B lymphocytes. (2001) (45)
- Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase. (1973) (45)
- The production of meta-tritiotyrosine from p-tritiophenylalanine by phenylalanine hydroxylase. (1966) (45)
- Purines in cellular signaling : targets for new drugs (1990) (44)
- Alkaloids of neotropical poison frogs (Dendrobatidae). (1982) (44)
- CYCLIC ADENOSINE 3′,5′‐MONOPHOSPHATE FORMATION IN GUINEA‐PIG BRAIN SLICES: EFFECT OF H1‐ AND H2‐HISTAMINERGIC AGONISTS (1976) (44)
- Antinociceptive effects of the alkaloid epibatidine: Further studies on involvement of nicotinic receptors (1995) (44)
- Alkaloids from Australian frogs (Myobatrachidae): pseudophrynamines and pumiliotoxins. (1990) (44)
- Pseudophrynamine A: an unusual prenyl pyrrolo[2,3-b]indole ester from an Australian frog, Pseudophryne coriacea (Myobatrachidae) (1988) (44)
- Absence of tetrodotoxins in a captive-raised riparian frog, Atelopus varius. (1997) (44)
- Calmodulin stimulation of adenylate cyclase in rat brain membranes does not require GTP. (1982) (43)
- Maitotoxin, a potent, general activator of phosphoinositide breakdown (1989) (43)
- Accumulation of adenosine 3',5'-monophosphate in rat brain slices: effects of prostaglandins. (1975) (43)
- Interactions of bupivacaine with ionic channels of the nicotinic receptor. Analysis of single-channel currents. (1984) (43)
- Diethylstilbestrol-elicited accumulation of cyclic AMP in incubated rat hypothalamus. (1975) (43)
- The effect of histamines and other compounds on the formation of adenosine 3′,5′‐monophosphate in slices from cerebral cortex (1970) (43)
- Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice. (1994) (42)
- Uptake and binding of dopamine and 6-hydroxydopamine in murine neuroblastoma and fibroblast cells. (1976) (42)
- A role for central A3-adenosine receptorsMediation of behavioral depressant effects (1993) (42)
- Phenolic antioxidants: potent inhibitors of the (Ca2+ + Mg2+‐ATPase of sarcoplasmic reticulum (1986) (42)
- N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. (1991) (42)
- Effect of membrane depolarization and biogenic amines on the formation of cyclic AMP in incubated brain slices. (1970) (41)
- The use of thin-layer chromatography for the analysis of drugs. Isolation and identification of barbiturates and nonbarbiturate hypnotics from urine, blood and tissues. (1963) (41)
- Effects of the amphiphilic peptides melittin and mastoparan on calcium influx, phosphoinositide breakdown and arachidonic acid release in rat pheochromocytoma PC12 cells. (1992) (41)
- The synthesis of 2,4,5-trihydroxyphenylalanine (6-hydroxydopa). A centrally active norepinephrine-depleting agent. (1969) (41)
- Glutamate- and veratridine-elicited accumulations of cyclic AMP in brain slices: a role for factors which potentiate adenosine-responsive systems (1980) (41)
- Brain α-adrenergic receptors: comparison of [3H]WB 4101 binding with norepinephrine-stimulated cyclic AMP accumulation in rat cerebral cortex (1978) (41)
- Alkylxanthines as research tools. (2000) (41)
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- Synthesis of alkaloid 223A and a structural revision. (2002) (40)
- Catechol O-Methyltransferase: III. m- and p-O-Methylation of Catecholamines and Their Metabolites (1970) (40)
- Interrelationship between catecholamine-stimulated formation of adenosine 3',5'-monophosphate in cerebellar slices and inhibitory effects on cerebellar Purkinje cells: antagonism by neuroleptic compounds. (1976) (39)
- The accumulation of cyclic AMP and cyclic GMP in guinea pig brain slices. Effect of calcium ions, norepinephrine and adenosine. (1977) (39)
- Alkaloids from dendrobatid poison frogs: Further cis-decahydroquinolines and 8-methylindolizidines (1991) (39)
- THE USE OF THIN-LAYER CHROMATOGRAPHY OF DRUGS. IDENTIFICATION AND ISOLATION TRANQUILIZERS AND OF ANTIHISTAMINICS IN TISSUES (1963) (39)
- The migration of deuterium during aryl hydroxylation. II. Effect of induction of microsomal hydroxylases with phenobarbital or polycyclic aromatic hydrocarbons. (1969) (38)
- Indolizidine 239Q and quinolizidine 275I. Major alkaloids in two Argentinian bufonid toads (Melanophryniscus). (2008) (38)
- Analogues of Adenosine, Theophylline, and Caffeine: Selective Interactions with A1 and A2 Adenosine Receptors (1987) (38)
- A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects. (1987) (37)
- 8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors. (1988) (37)
- Catechol O-methyltransferase. 3. M- and p-O-methylation of catecholamines and their metabolites. (1970) (36)
- Arene Oxides‐Oxepins (1973) (36)
- Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. (1993) (36)
- Dihydroxytryptamines: effects on noradrenergic function in mouse heart in vivo. (1975) (36)
- Sciatic and peroneal nerve injury: a complication of vaginal operations. (1967) (36)
- Assay and partial purification of epoxide hydrase from rat liver microsomes. (1974) (36)
- Phantasmidine: an epibatidine congener from the ecuadorian poison frog Epipedobates anthonyi. (2010) (36)
- Chemical and Enzymatic Routes to Methoxydopamines (1961) (36)
- Adenosine Receptors:Selective Agonists and Antagonists (1995) (36)
- Alkaloids of Anuran Skin: Antimicrobial Function? (2005) (35)
- Hydroxylation-induced migrations of tritium in several substrates of liver aryl hydroxylases. (1967) (35)
- Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. (1989) (35)
- Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. (1993) (35)
- Loperamide: a positive modulator for store-operated calcium channels? (1997) (35)
- 7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists. (1990) (35)
- A stereospecific synthesis of (+/-)-5,8-disubstituted indolizidines and (+/-)-1,4-disubstituted quinolizidines found in poison frog skins. (2000) (34)
- Deuterium migration during the acid-catalyzed dehydration of 6-deuterio-5,6-dihydroxy-3-chloro-1,3-cyclohexadi-ene, a nonenzymic model for the NIH shift (1967) (34)
- Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems. (1976) (34)
- Inhibitors of norepinephrine metabolism in vivo. (1959) (34)
- Arene oxides as intermediates in the metabolism of aromatic substrates: alkyl and oxygen migrations during isomerization of alkylated arene oxides. (1971) (34)
- Epiquinamide: a poison that wasn't from a frog that was. (2009) (33)
- Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptorion channel complex of torpedo electroplax (1986) (33)
- Macromolecular sites for specific neurotoxins and drugs on chemosensitive synapses and electrical excitation in biological membranes. (1988) (33)
- METHYLATION AND DEMETHYLATION IN RELATION TO THE IN VITRO METABOLISM OF MESCALINE (1962) (33)
- Pumiliotoxin B binds to a site on the voltage-dependent sodium channel that is allosterically coupled to other binding sites. (1988) (33)
- Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors. (2005) (32)
- The pharmacology of batrachotoxin. VII. Structure-activity relationships and the effects of pH. (1975) (32)
- Maitotoxin: effects on calcium channels, phosphoinositide breakdown, and arachidonate release in pheochromocytoma PC12 cells. (1990) (32)
- Quantitative studies on the hydroxylation-induced migration of deuterium and tritium during phenylalanine hydroxylation. (1967) (32)
- N,N-acetals as N-acyliminium ion precursors: synthesis and absolute stereochemistry of epiquinamide. (2008) (32)
- Altered responsiveness of adenosine 3′,5′-monophosphate-generating systems in rat cortical slices after lesions of the medial forebrain bundle (1975) (32)
- Epibatidine: A Novel (Chloropyridyl)azabicycloheptane with Potent Analgesic Activity from an Ecuadoran Poison Frog. (1992) (32)
- Production of m-methyltyrosine and p-hydroxymethylphenylalanine from p-methylphenylalanine by phenylalanine hydroxylase. (1968) (32)
- Migration of deuterium during aryl hydroxylation. 3. Effect of ortho- and meta- substituents. (1969) (32)
- Phospholipase D-catalyzed hydrolysis of phosphatidylcholine occurs with P-O bond cleavage. (1991) (32)
- Skin as a Toxin Storage Organ in the Endemic New Guinean Genus Pitohui (2009) (32)
- Photolysis of pyridine-N-oxide: an oxygen atom transfer model for enzymatic oxygenation, arene oxide formation, and the NIH shift (1970) (32)
- N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors. (1986) (31)
- Caffeine Analogs: Effects on Ryanodine-Sensitive Calcium-Release Channels and GABAA Receptors (2003) (31)
- 1980 Taxonomy and Ecology of Dendrobates bombetes , a New Andean Poison Frog With New Skin Toxins (31)
- Chemistry of Catecholamines: Revised Structures for the Iodoaminochromes (1963) (31)
- Optically active 1,2-naphthalene oxide (1970) (30)
- Catechol-O-methyltransferase. I. An enzymatic assay for cardiac norepinephrine. (1969) (30)
- 6beta-Acetoxynortropane: a potent muscarinic agonist with apparent selectivity toward M2-receptors. (1998) (30)
- Individual and Geographic Variation of Skin Alkaloids in Three Species of Madagascan Poison Frogs (Mantella) (2008) (30)
- Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities. (2000) (30)
- A [3H]amine congener of 1,3‐dipropyl‐8‐phenylxanthine (1986) (30)
- N-methyldecahydroquinolines: an unexpected class of alkaloids from Amazonian poison frogs (Dendrobatidae). (2009) (30)
- Analogues of 1,3-dipropyl-8-phenylxanthine: enhancement of selectivity at A1-adenosine receptors by aryl substituents. (1986) (29)
- Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells: Effects of agonists, antagonists, and noncompetitive blockers (1991) (29)
- The pharmacology of pumiliotoxin-B. I. Interaction with calcium sites in the sarcoplasmic reticulum of skeletal muscle. (1981) (29)
- Pumiliotoxin alkaloids: a new class of sodium channel agents. (1990) (29)
- Synthesis and adrenergic activity of ring-fluorinated phenylephrines. (1986) (28)
- Intramolecular migration of deuterium and tritium during enzymic hydroxylation of p-deuteroacetanilide and p-tritioacetanilide. (1967) (28)
- Calcium-dependent effects of maitotoxin on phosphoinositide breakdown and on cyclic AMP accumulation in PC12 and NCB-20 cells. (1989) (28)
- Genetic expression of the induction of epoxide hydrase and aryl hydrocarbon hydroxylase activities in the mouse by phenobarbital or 3-methylcholanthrene. (1973) (28)
- Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms. (1991) (28)
- Aerobic aromatic hydroxylation catalyzed by horseradish peroxidase: absense of NIH shift. (1970) (28)
- Structure of alkaloid 275A, a novel 1-azabicyclo[5.3.0]decane from a dendrobatid frog, Dendrobates lehmanni: synthesis of the tetrahydrodiastereomers. (2001) (27)
- Multiple neurotransmitter receptors in the brain: amines, adenosine, and cholecystokinin. (1981) (27)
- A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid A new class of A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid pumiliotoxin B (8-hydroxy-8-methyl-6-alkylidene (1985) (27)
- The pharmacology of batrachotoxin. V. A comparative study of membrane properties and the effect of batrachotoxin on sartorius muscles of the frogs Phyllobates aurotaenia and Rana pipiens. (1973) (27)
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- Rapid analysis of tryptophan hydroxylase in rat tissue using 5- 3 H-tryptophan. (1971) (27)
- Evidence That a Novel 8‐Phenyl‐Substituted Xanthine Derivative is a Cardioselective Adenosine Receptor Antagonist In Vivo (1987) (26)
- Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. (1990) (26)
- Decahydroquinoline alkaloids: Noncompetitive blockers for nicotinic acetylcholine receptor-channels in pheochromocytoma cells andTorpedo electroplax (1991) (26)
- On the inability of tryptamine to serve as a precursor of serotonin. (1959) (25)
- Isotope studies on the mechanism of action of adrenal tyrosine hydroxylase. (1968) (25)
- Inhibition of platelet aggregation by adenosine receptor agonists (1994) (25)
- Effect of batrachotoxin on the electroplax of electric eel: evidence for voltage-dependent interaction with sodium channels. (1977) (25)
- Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives. (1985) (25)
- Alkaloid 223A: the first trisubstituted indolizidine from dendrobatid frogs. (1997) (25)
- Pumiliotoxin alkaloids: relationship of cardiotonic activity to sodium channel activity and phosphatidylinositol turnover. (1988) (24)
- Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors. (2007) (24)
- Localization of glutamate decarboxylase on line-immunoelectrophoresis and two-dimensional electrophoresis by use of the radioactive suicide substrate [2-3H]-gamma-acetylenic GABA. (1980) (24)
- Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig. (1991) (24)
- Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants. (1990) (24)
- Interactions of bupivacaine with ionic channels of the nicotinic receptor. Electrophysiological and biochemical studies. (1984) (24)
- Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). (1989) (24)
- Mechanism of maitotoxin-stimulated phosphoinositide breakdown in HL-60 cells. (1990) (24)
- A new subclass of alkaloids from a dendrobatid poison frog: a structure for deoxypumiliotoxin 251H. (1995) (23)
- Regulation of cyclic AMP levels in brain tissue. (1972) (23)
- Effect of calmidazolium analogs on calcium influx in HL-60 cells. (2000) (23)
- Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. I. Blockade of the ionic channel. (1984) (23)
- Mesoionic xanthine analogues: antagonists of adenosine receptors. (1984) (23)
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- The "pink spot," 3,4-dimethoxyphenylethylamine, common tea, and schizophrenia. (1970) (23)
- The enantioselective synthesis of poison-frog alkaloids (−)-203A, (−)-209B, (−)-231C, (−)-233D, and (−)-235B″ (2006) (23)
- Effect of proteases and protease inhibitors on adenylate cyclase activity in rat cerebral cortical membranes. (1979) (22)
- Interaction of pumiliotoxin B with an "alkaloid-binding domain" on the voltage-dependent sodium channel. (1992) (22)
- Cone biopsy: an outpatient procedure. (1980) (22)
- Syntheses and adrenergic activities of ring-fluorinated epinephrines. (1988) (22)
- Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists. (1982) (22)
- Recent Studies on the Centrally Active Endogenous Amines (1963) (22)
- Chronic effects of ethanol on central adenosine function of mice (1994) (22)
- Calcium-dependent 3':5'-cyclic nucleotide phosphodiesterase. Inhibition of basal activity at physiological levels of potassium ions. (1978) (22)
- Local anesthetics differentiate dihydropyridine calcium antagonist binding sites in rat brain and cardiac membranes. (1987) (22)
- A name for the poison frog of Cordillera Azul, eastern Peru, with notes on its biology and skin toxins (Dendrobatidae). American Museum novitates ; no. 2674 (1979) (22)
- The binding of fluorocatecholamines to adrenergic and dopaminergic receptors in rat brain membranes. (1980) (22)
- Isomers of 2,4,5-trihydroxyphenethylamine (6-hydroxydopamine): long-term effects on the accumulation of (3H)-norepinephrine in mouse heart in vivo. (1973) (21)
- Stimulation of calcium release by caffeine analogs in pheochromocytoma cells. (1993) (21)
- Treatment of Vaginal Dysplasia and Carcinoma In Situ with Topical 5‐Fluorouracil (1980) (21)
- Loperamide: novel effects on capacitative calcium influx (2000) (21)
- A simple radiometric assay for microsomal aryl hydroxylase activity. (1970) (21)
- Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells (1988) (21)
- Effects of mastoparan and related peptides on phosphoinositide breakdown in HL-60 cells and cell-free preparations. (1991) (21)
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- Cis- and trans-configurations of α,α′-disubstituted piperidines and pyrrolidines by GC-FTIR; application to decahydroquinoline stereochemistry (1994) (20)
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- Mammalian alkaloids. 8. Synthesis and biological effects of tetrahydropapaveroline related 1-benzyltetrahydroisoquinolines. (1980) (19)
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- The pharmacology of batrachotoxin. VI. Effects on the mammalian motor nerve terminal. (1974) (19)
- Calcium ion-elicited accumulations of cyclic GMP in guinea pig cerebellar slices. (1977) (19)
- Bis(monoacylglycero)phosphate from PC12 cells, a phospholipid that can comigrate with phosphatidic acid: molecular species analysis by fast atom bombardment mass spectrometry. (1992) (19)
- Local anesthetics: comparison of effects on batrachotoxin-elicited sodium flux and phosphoinositide breakdown in guinea pig cerebral cortical synaptoneurosomes. (1988) (18)
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- Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. (1987) (18)
- Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. (1982) (18)
- [Is caffeine addictive? The most widely used psychoactive substance in the world affects same parts of the brain as cocaine]. (1998) (18)
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- Cardiotonic activities of pumiliotoxin B, pyrethroids and a phorbol ester and their relationships with phosphatidylinositol turnover. (1987) (18)
- Pharmacology of the alkaloid pumiliotoxin-B. II. Possible involvement of calcium and sodium-dependent processes in nerve and skeletal muscle. (1987) (18)
- Effect of forskolin on alterations of vascular permeability induced with bradykinin, prostaglandin E1, adenosine, histamine and carrageenin in rats. (1983) (17)
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- pumiliotoxins: magnetic resonance spectral assignments and structural definition of pumiliotoxins A and B and related allopumiliotoxins (1984) (17)
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- Homoepiboxidines: further potent agonists for nicotinic receptors. (2004) (17)
- Metabolism of acetanilide with hepatic microsomes and reconstituted cytochrome monoxygenase systems. (1974) (17)
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- Diverse effects of sphingosine on calcium mobilization and influx in differentiated HL-60 cells. (2000) (17)
- Inhibitors of store‐operated calcium channels: Imidazoles, phenothiazines, and other tricyclics (1999) (17)
- Autoradiographic localization of mouse brain adenosine receptors with an antagonist ([3H]xanthine amine congener) ligand probe (1988) (17)
- Activation of phosphoinositide breakdown and elevation of intracellular calcium in a rat RBL‐2H3 mast cell line by adenosine analogs: Involvement of A3‐adenosine receptors? (1996) (17)
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- Enantioselective syntheses of poison-frog alkaloids : 219F and 221I and an epimer of 193E (2006) (16)
- Effects of combinations of methylxanthines and adenosine analogs on locomotor activity in control and chronic caffeine‐treated mice (1993) (16)
- Histrionicotoxins : Carbon-13 magnetic resonance spectral assignments and structural definition of further alkaloids from poison frogs (dendrobatidae) (1983) (16)
- Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. II. Enhancement of desensitization. (1984) (16)
- 1-Isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices. (1979) (15)
- Roughing it: a mantellid poison frog shows greater alkaloid diversity in some disturbed habitats. (2010) (15)
- Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. (1996) (15)
- A 1,4-disubstituted quinolizidine from a Madagascan mantelline frog (Mantella). (1996) (15)
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- Intramolecular Migrations during Hydroxylation of Aromatic Compounds: The NIH Shift (1968) (15)
- 7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists. (1988) (15)
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- Enzymatic hydration of 8,9-indan oxide, Homoallylic addition of water. (1970) (14)
- Adenosine Agonists and Antagonists (1990) (14)
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- A simple direct assay of 3',5'-cyclic nucleotide phosphodiesterase activity based on the use of polyacrylamide-bononate affinity gel chromatography. (1979) (14)
- Modulation of forskolin binding to rat brain membranes. (1985) (14)
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- Adenosine analogs with covalently attached lipids have enhanced potency at A1‐adenosine receptors (1987) (14)
- Release of norepinephrine from brain vesicular preparations: Effects of an adenylate cyclase activator, forskolin, and a phosphodiesterase inhibitor (1982) (14)
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- The synthesis of dehydrobufotenine. (1967) (13)
- Enzymic and nonenzymic hydroxylation and chlorination of p-deuteroanisole. (1968) (13)
- Combination of 5‐Fluorouracil and Radiation as Primary Therapy of Carcinoma of the Cervix (1968) (12)
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- Local anesthetic properties of opioids and phencyclidines: Interaction with the voltage-dependent, batrachotoxin binding site in sodium channels (1985) (11)
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- High-affinity binding of forskolin to rat brain membranes. (1985) (11)
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- The absolute configuration of the side chain diol moiety of the poison-frog alkaloid pumiliotoxin B (1982) (9)
- Chapter 4 The Nature and Origin of Amphibian Alkaloids (1998) (9)
- Release of norepinephrine and dopamine from brain vesicular preparations: Effects of calcium antagonists (1982) (9)
- Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol. (1991) (9)
- STRUCTURE–ACTIVITY CORRELATIONS IN TRIHYDROXYPHENETHYLAMINES AND DIHYDROXYTRYPTAMINES RELATIONSHIP TO CYTOTOXICITY IN ADRENERGIC AND SEROTONERGIC NEURONS (1974) (9)
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- Ammonia chemical ionization tandem mass spectrometry in structure determination of alkaloids. I. Pyrrolidines, piperidines, decahydroquinolines, pyrrolizidines, indolizidines, quinolizidines and an azabicyclo[5.3.0]decane. (1999) (9)
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- Inhibition of Calcium‐Dependent ATPase from Sarcoplasmic Reticulum by a New Class of Indolizidine Alkaloids, Pumiliotoxins A, B, and 251D (1982) (7)
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- Histrionicotoxins: Effects on binding of radioligands for sodium, potassium, and calcium channels in brain membranes (1986) (5)
- Procaine isothiocyanate: An irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels (1990) (5)
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- The Isolation and Structure of the Novel cis-Fused Indolizidine 249H from Frog Skin: cis- vs. trans-Fused Indolizidines Distinguished by NMR (1998) (5)
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- Enantioselective Synthesis of Poison-Frog Alkaloid 237D (I) and Determination of Absolute Stereochemistry. (2005) (0)
- Identification of Histrionicotoxins by GC-MS and GC-FTIR: Photo- and Chemical-Artefacts and Revised 13C NMR Assignments. (1992) (0)
- MAMMALIAN ALKALOIDS. 8. SYNTHESIS AND BIOLOGICAL EFFECTS OF TETRAHYDROPAPAVEROLINE RELATED 1-BENZYLTETRAHYDROISOQUINOLINES (1980) (0)
- Enantioselective Syntheses of Poison-Frog Alkaloids: 219F and 221I and an Epimer (I) of 193E. (2006) (0)
- Living Cytology—Revisited: In Vitro Demonstration of Intraabdominal Adenocarcinomatosis (1979) (0)
- 7,8-DIOXOCHLORPROMAZINE, SYNTHESIS AND PROPERTIES (1975) (0)
- PRELIMINARY EVALUATION OF SKIN (0)
- SYNTHESIS OF PUMILIOTOXIN C (1976) (0)
- Antagonism of alpha- and beta-adrenergic-mediated accumulations of cyclic AMP in rat cerebral cortical slices by the beta-antagonist (-)alprenolol. (1976) (0)
- ILI-5 Potent Neurotoxin of Chiriquitoxin and Zetekitoxin from the Panamanian Golden Frogs Atelopus Species(Isolation and Structure Elucidation of Natural Products) (2006) (0)
- NOREPINEPHRINE UPTAKE SITES IN CARDIAC TISSUE, LACK OF AFFINITY OF 6-HYDROXYNOREPINEPHRINE AND RELATED COMPOUNDS (1975) (0)
- 499 – ACTIONS OF NEUROTOXINS ON THE ACEIYLCHOLINE RECEPTOR-IONIC CONDUCTANCE MODULATOR UNIT AND ON SODIUM CHANNELS (1977) (0)
- The synthesis of certain 6- and 9- substituted purines of biological interest (1955) (0)
- Separation of the enantiomers of the aminonaphthyl-alanines by paper chromatography. (1966) (0)
- Pseudophrynamine A: An Unusual Prenyl Pyrrolo(2,3-b)indole Ester from an Australian Frog, Pseudophryne coriacea (Myobatrachidae). (1988) (0)
- SIGNIFICANCE OF THE NIH SHIFT WITH RESPECT TO LIVER MICROSOME HYDROXYLATIONS (1969) (0)
- Analogues of 1,3-Dipropyl-S-phenylxanthine: Enhancement of Selectivity at A1-Adenosine Receptors by Aryl Substituents. (1987) (0)
- Potential effector of Grb7 family of signaling proteins (1998) (0)
- Advances in natural products chemistry, extraction, and isolation of biologically active compounds Edited by , Halsted Press, New York, 1981 (1982) (0)
- Facile Synthesis of 4-Piperidones by Condensation of an α,β- Unsaturated Ketone, an Aldehyde and Ammonia: Synthesis of the Dendrobatid Frog Alkaloid 241D (XII). (1995) (0)
- Chiral Synthesis of Poison‐Frog Alkaloids 251N and 221K. (2007) (0)
- Convulsant properties of methylxanthines, potential cognitive enhancers in dementia syndromes (1990) (0)
- ARENE OXIDES-OXEPINS (1974) (0)
- STRUCTURE-ACTIVITY RELATIONSHIPS FOR ACTIVATION OF ADENYLATE CYCLASE BY THE DITERPENE FORSKOLIN AND ITS DERIVATIVES (1983) (0)
- GEPHYROTOXINS, HISTRIONICOTOXINS AND PUMILIOTOXINS FROM THE NEOTROPICAL FROG DENDROBATES HISTRIONICUS (1977) (0)
- Contents to volume 184 (2001) (0)
- A quintuplet gestation. (1960) (0)
- YUICHI KANAOKA: A Pioneer in Chemical Biology (2003) (0)
- MESOIONIC XANTHINE ANALOGS: ANTAGONISTS OF ADENOSINE RECEPTORS (1985) (0)
- N6,9‐Disubstituted Adenines: Effect on Affinity for Adenosine Receptors of a Chiral Center in the 9‐Substituent. (2010) (0)
- Additions and Corrections - Deuterium Migration during the Acid-Catalyzed Dehydration of 6-Deutrio-5,6-dihydroxy-3-chloro-1,3-cyclohexadiene, a Nonenzymatic Model for the NIH Shift. (1968) (0)
- The Enantioselective Synthesis of Poison-Frog Alkaloids (—)-203A, (—)-209B, (—)-231C, (—)-233D, (—)-235B“. (2006) (0)
- Subject Index, Vol. 42, 1991 (1991) (0)
- 1‐Methyl‐4‐substituted‐1H‐pyrazolo(3,4‐b)pyridine‐5‐carboxylic Acid Derivatives: Effect of Structural Alterations on Activity at A1 and A2 Adenosine Receptors. (1995) (0)
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