John W. Holaday
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(Suggest an Edit or Addition)John W. Holaday's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Release of multiple hormones by a direct action of interleukin-1 on pituitary cells. (1987) (666)
- Cardiovascular effects of endogenous opiate systems. (1983) (578)
- Naloxone reversal of endotoxin hypotension suggests role of endorphins in shock (1978) (456)
- Suppression of macrophage activation and T-lymphocyte function in hypoprolactinemic mice. (1988) (383)
- Opiate antagonists: a role in the treatment of hypovolemic shock. (1979) (323)
- Opiate antagonist improves neurologic recovery after spinal injury (1981) (264)
- Antiangiogenic activity of prostate-specific antigen. (1999) (214)
- Naloxone acts at central opiate receptors to reverse hypotension, hypothermia and hypoventilation in spinal shock (1980) (213)
- Thyrotropin-Releasing Hormone Improves Neurologic Recovery after Spinal Trauma in Cats (1981) (205)
- Endorphins in experimental spinal injury: Therapeutic effect of naloxone (1981) (197)
- Inhibition of lymphocyte proliferation by antibodies to prolactin 1 (1989) (171)
- Thyrotropin-releasing hormone improves cardiovascular function in experimental endotoxic and hemorrhagic shock. (1981) (155)
- Thyrotropin releasing hormone antagonizes β endorphin hypothermia and catalepsy (1978) (151)
- Naloxone treatment of endotoxin shock: stereospecificity of physiologic and pharmacologic effects in the rat. (1980) (140)
- Immunosuppressive effects of chronic morphine treatment in mice. (1987) (138)
- Blockade of opiate receptors with naloxone improves survival and cardiac performance in canine endotoxic shock. (1980) (137)
- beta-FNA binds irreversibly to the opiate receptor complex: in vivo and in vitro evidence. (1988) (133)
- Morphine pellet-induced immunomodulation in mice: temporal relationships. (1988) (130)
- Role of adrenal cortical activation in the immunosuppressive effects of chronic morphine treatment. (1991) (118)
- Blood-brain barrier: endogenous modulation by adrenal-cortical function. (1985) (116)
- Comparison of thyrotropin‐releasing hormone (TRH), naloxone, and dexamethasone treatments in experimental spinal injury (1983) (116)
- Diurnal variation of plasma testosterone and cortisol. (1972) (115)
- Cardiovascular consequences of endogenous opiate antagonism. (1983) (109)
- Repeated electroconvulsive shock or chronic morphine treatment increases the number of 3H-D-Ala2,D-Leu5-enkephalin binding sites in rat brain membranes. (1982) (105)
- Naloxone reversal of hypovolemic shock in dogs. (1981) (102)
- Rapid release of multiple hormones from rat pituitaries perifused with recombinant interleukin-1. (1989) (100)
- Unique behavioral effects of beta endorphin and their relationship to thermoregulation and hypothalamic function. (1978) (96)
- Experimental endotoxin shock: the pathophysiologic function of endorphins and treatment with opiate antagonists. (1980) (95)
- Calcium administration increases the mortality of endotoxic shock in rats. (1989) (94)
- Opiate-like effects of electroconvulsive shock in rats: a differential effect of naloxone on nociceptive measures. (1980) (92)
- Administration of a liposomal FGF-2 peptide vaccine leads to abrogation of FGF-2-mediated angiogenesis and tumor development. (2000) (91)
- Comparison of early and late naloxone treatment in experimental spinal injury (1982) (89)
- Morphine tolerance increases -noncompetative d binding sites? (1986) (88)
- Chronic administration of morphine and naltrexone up-regulate mu-opioid binding sites labeled by [3H][D-Ala2,MePhe4,Gly-ol5]enkephalin: further evidence for two mu-binding sites. (1989) (87)
- Endorphin-parasympathetic interaction in spinal shock (1980) (84)
- U50,488, a highly selective kappa opioid: anticonvulsant profile in rats. (1986) (83)
- Synchronized ultradian cortisol rhythms in monkeys: persistence during corticotropin infusion (1977) (82)
- Neurological dysfunction after intrathecal injection of dynorphin A (1-13) in the rat. II. Nonopioid mechanisms mediate loss of motor, sensory and autonomic function. (1988) (81)
- Adrenal steroids indirectly modulate morphine and beta-endorphin effects. (1979) (80)
- Naloxone or TRH fails to improve neurologic deficits in gerbil models of "stroke". (1982) (80)
- beta-Endorphin: pituitary and adrenal glands modulate its action. (1977) (80)
- Endorphins may function in heat adaptation. (1978) (80)
- Repeated electroconvulsive shock (ECS) and morphine tolerance: demonstration of cross-sensitivity in the rat. (1981) (74)
- The opiate antagonist naloxone modifies the effects of electroconvulsive shock (ECS) on respiration, blood pressure and heart rate (1979) (70)
- Morphine-induced immunomodulation is not related to serum morphine concentrations. (1988) (65)
- Intrathecal dynorphin A1–13 and dynorphin A3–13 reduce rat spinal cord blood flow by non-opioid mechanisms (1987) (63)
- Endogenous opioid systems: Physiological role in the self-limitation of seizures (1985) (61)
- Upregulation of the opioid receptor complex by the chronic administration of morphine: A biochemical marker related to the development of tolerance and dependence (1991) (61)
- Highly Efficient, Large Volume Flow Electroporation (2002) (59)
- Chronic administration of morphine and naltrexone up-regulate[3H][d-ala2,d-leu5]enkephalin binding sites by different mechanisms (1988) (59)
- The kappa opioid agonist U-50,488H antagonizes respiratory effects of mu opioid receptor agonists in conscious rats. (1993) (58)
- Multiple opioid receptors: Evidence for μ -δ binding site interactions in endotoxic shock (1983) (57)
- Anticonvulsant effects of mu (DAGO) and delta (DPDPE) enkephalins in rats (1988) (53)
- Selective kappa antagonist properties of nor-binaltorphimine in the rat MES seizure model. (1989) (52)
- Opiate-like electroencephalographic and behavioral effects of electroconvulsive shock in rats. (1981) (49)
- Multiple opioid receptors in endotoxic shock: evidence for delta involvement and mu-delta interactions in vivo. (1984) (48)
- Opiate antagonist improves neurologic recovery after spinal injury. (1982) (47)
- Adrenalectomy blocks pressor responses to naloxone in endotoxic shock: evidence for sympathomedullary involvement. (1983) (46)
- The anticonvulsant effects of dadle are primarily mediated by activation of δ opioid receptors: interactions between δ and μ receptor antagonists (1985) (46)
- Prolactin and Immune Function (1991) (44)
- Thyrotropin-releasing hormone improves neurologic recovery after spinal trauma in cats. (1982) (44)
- Hypophysectomy alters cardiorespiratory variables: central effects of pituitary endorphins in shock. (1981) (44)
- Prolactin and prolactin secretagogues reverse immunosuppression in mice treated with cysteamine, glucocorticoids, or cyclosporin-A (1992) (44)
- Thyrotropin releasing hormone: autonomic effects upon cardiorespiratory function in endotoxic shock (1983) (44)
- Allosteric Coupling Among Opioid Receptors: Evidence for an Opioid Receptor Complex (1993) (44)
- ICI 174864, a putative δ opioid antagonist, reverses endotoxemic hypotension: Pretreatment with dynorphin 1–13, a κ agonist, blocks this action (1984) (42)
- Opioid effects on plasma concentrations of luteinizing hormone and prolactin in the adult male rhesus monkey. (1985) (41)
- Relations between behavioral arousal and plasma cortisol levels in monkeys performing repeated free-operant avoidance sessions. (1976) (41)
- Failure vasopressin and oxytocin to antagonize acute morphine antinociception or facilitate narcotic tolerance development. (1978) (40)
- Effects of NMDA receptor antagonists following spinal ischemia in the rabbit (1990) (39)
- Ultradian glucocorticoid rhythms in monkeys and rats continue during stress. (1984) (39)
- Endogenous opioids and their receptors. Evidence for involvement in the postictal effects of electroconvulsive shock. (1986) (39)
- M 154,129, a putative delta antagonist, reverses endotoxic shock without altering morphine analgesia. (1982) (38)
- Evidence for a role of endorphins in the cardiovascular pathophysiology of primate shock. (1988) (37)
- Opiate Antagonists: A Role in the Treatment of Hypovolemic Shock (1980) (37)
- Cardiorespiratory effects of μ and δ opiate agonists following third or fourth ventricular injections (1982) (36)
- Dopamine partially mediates the cardiovascular effects of naloxone after spinal injury (1981) (34)
- Chronic morphine upregulates a mu-opiate binding site labeled by [3H]cycloFOXY: a novel opiate antagonist suitable for positron emission tomography. (1987) (33)
- Temporal changes in growth hormone, cortisol, and glucose: relation to light onset and behavior. (1975) (30)
- Thyrotropin releasing hormone improves blood pressure and survival in endotoxic shock. (1981) (30)
- Glucagon's chronotropic action is calcium dependent. (1987) (29)
- Neuropeptides in shock and traumatic injury: sites and mechanisms of action (1984) (29)
- Cysteamine produces dose-related bidirectional immunomodulatory effects in mice. (1989) (29)
- Cardiovascular effects of dynorphin A (1–13) in conscious rats and its modulation of morphine bradycardia over time (1987) (29)
- Opioids in immunologic processes (1993) (28)
- Neurological dysfunction after intrathecal injection of dynorphin A (1-13) in the rat. I. Injection procedures modify pharmacological responses. (1988) (28)
- Electroencephalographic assessment of the role of δ receptors in opioid peptide - induced seizures (1984) (26)
- GLUCAGON REVERSES THE HYPOTENSION AND BRADYCARDIA OF VERAPAMIL OVERDOSE IN RATS (1985) (25)
- Hindlimb paralytic effects of prodynorphin-derived peptides following spinal subarachnoid injection in rats. (1988) (25)
- Action of naloxone and TRH on the autonomic regulation of circulation. (1982) (24)
- Electroconvulsive Shock Activates Endogenous Opioid Systems: Behavioral and Biochemical Correlates (1986) (24)
- Glucagon: endocrine effects and calcium involvement in cardiovascular actions in dogs. (1986) (23)
- Effects of hypophysectomy and ACTH on opiate tolerance and physical dependence. (1979) (23)
- Naloxazone lacks therapeutic effects in endotoxic shock yet blocks the effects of naloxone. (1983) (21)
- Immunomodulatory effects of chronic morphine treatment: pharmacologic and mechanistic studies. (1990) (21)
- Cortisol secretion and clearance in the rhesus monkey. (1977) (21)
- Neurologic deficits and neuronal injury in rats resulting from nonopioid actions of the delta opioid receptor antagonist ICI 174864. (1988) (21)
- Endogenous opioids in spinal cord injury: a critical evaluation. (1986) (21)
- Determination of chlorpromazine and its major metabolites by gas chromatography/mass spectrometry: application to biological fluids. (1985) (21)
- Interaction of β‐funaltrexamine with [3H]cycloFOXY binding in rat brain: Further evidence that β‐FNA alkylates the opioid receptor complex (1991) (20)
- Naloxone potentiates epinephrine's pressor actions in endotoxemic rats. (1988) (20)
- Hypercalcemia attenuates blood pressure response to epinephrine. (1988) (20)
- Repeated electroconvulsive shock: effect on sodium dependency and regional distribution of opioid-binding sites. (1987) (20)
- A selective role for delta-receptors in the regulation of opioid-induced changes in seizure threshold. (1983) (19)
- Opioids and neuropeptides: mechanisms in circulatory shock. (1985) (19)
- Naloxozone pretreatment modifies cardiorespiratory, temperature, and behavioral effects of morphine (1983) (17)
- Modulation of Endogenous Opioid Systems by Electroconvulsive Shock. (1989) (17)
- Electroconvulsive shock results in a functional activation of endorphin systems. (1981) (16)
- Respiratory and cardiovascular effects of thyrotropin-releasing hormone as modified by isoflurane, enflurane, pentobarbital and ketamine (1989) (16)
- 6 – Neurobiology of β-Endorphin and Related Peptides (1981) (16)
- Morphine tolerance increases mu-noncompetitive delta binding sites. (1986) (15)
- Opiate antagonists in shock and trauma. (1984) (15)
- NALOXONE TREATMENT IN SHOCK (1981) (15)
- Evaluation of naloxone therapy for Escherichia coli sepsis in the baboon. (1988) (15)
- The therapeutic efficacy of opiate antagonists in hemorrhagic shock. (1989) (15)
- Endotoxin-induced hypocalcemia results in defective calcium mobilization in rats. (1987) (15)
- ICI 154,129, a δ-opioid receptor antagonist raises seizure threshold in rats (1984) (14)
- Protirelin (TRH): a potent neuromodulator with therapeutic potential. (1984) (14)
- Multiple opioid receptors in endotoxic shock : Evidence for 6 involvement and , u-6 interactions in vivo ( (13)
- Evidence for delta-receptor involvement in the post-ictal antinociceptive responses to electroconvulsive shock in rats. (1983) (12)
- Effects of TRH in Circulatory Shock and Central Nervous System Ischemia a (1989) (11)
- Antiangiogenic drugs: insights into drug development from endostatin, avastin and thalidomide. (2009) (11)
- ELECTROCONVULSIVE SHOCK (ECS) IN RATS: NALOXONE MODIFICATION OF POST-ECS BEHAVIORS PROVIDES EVIDENCE FOR FUNCTIONAL ENDORPHIN RELEASE (1980) (11)
- Pituitary opioid involvement in ECS-postictal electrogenesis and behavioral depression in rats (1984) (11)
- Dynorphin: cardiovascular consequences of opioid receptor interactions in normal and endotoxemic rats. (1984) (10)
- Thyrotropin releasing hormone antagonizes beta endorphin hypothermia and catalepsy. (1978) (10)
- Endorphins in Experimental Spinal Injury: Therapeutic Effects of Naloxone (1982) (10)
- Arginine8-vasopressin reduces spinal cord blood flow after spinal subarachnoid injection in rats. (1989) (10)
- Naloxone and ischemic neurologic deficits in the gerbil: is there an effect? (1982) (9)
- Thyrotropin releasing hormone: effects in monkeys and dogs subjected to experimental circulatory shock. (1987) (9)
- Multiple opiate receptors: functional implications. (1985) (9)
- Spinal shock and injury: experimental therapeutic approaches. (1983) (9)
- Strategies for attracting angel investors (2003) (9)
- Pretreatment of rats with the irreversible μ-receptor antagonist, β-FNA, fails to prevent naltrexone-induced upregulation of μ-opioid receptors (1990) (8)
- Intrathecal dynorphin A (1-13) and (3-13) reduce spinal cord blood flow by non-opioid mechanisms. (1986) (8)
- Glucagon is an antagonist of morphine bradycardia and antinociception. (1986) (8)
- Possible Function of β Endorphin (1979) (8)
- The effect of bromocryptine-induced hypoprolactinemia on xenogeneic and allogeneic skin graft survival in a mouse model. (1994) (8)
- NALOXONE AND THYROTROPIN RELEASING HORMONE HAVE ADDITIVE EFFECTS IN REVERSING ENDOTOXIC SHOCK (1981) (8)
- Intravenous beta-endorphin: Behavioral and physiological effects in conscious monkeys (1989) (7)
- TRH fails to antagonize the acute paralytic effects of intrathecal dynorphin A and substance P antagonists in the rat (1988) (7)
- In vivo interactions among opiate receptor agonists and antagonists. (1986) (7)
- Neuropeptides and spinal cord injury. (1982) (6)
- A study of the interaction of the alkylating agent, NIH10236, with opioid receptors in vitro and in vivo (1989) (6)
- Hindlimb paralytic effects of arginine vasopressin and related peptides following spinal subarachnoid injection in the rat (1988) (6)
- Dynorphin A (1-13): in vivo opioid antagonist actions and non-opioid anticonvulsant effects in the rat flurothyl test. (1986) (6)
- A role for endorphins in the pathophysiology of spinal cord injury. (1981) (6)
- Naloxone reverses the pathophysiology of shock through an antagonism of endorphin systems. (1981) (6)
- NALOXONE REVERSAL OF HYPOTENSION CAUSED BY SPINAL TRANSECTION (1980) (6)
- Opioid Peptides and Their Antagonists: A Role in Respiratory Function (1985) (5)
- The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists. (1985) (5)
- Is there a role for naloxone in the treatment of stroke? (1989) (5)
- Cardiorespiratory effects of mu and delta opiate agonists following third or fourth ventricular injections. (1982) (5)
- Opioids II (1993) (5)
- Neuroendocrine Regulation of Immune Function (1993) (4)
- Naloxone alteration of physiological parameters in spinally transected animals. (1979) (4)
- Multiple opioid receptors: evidence for mu-delta binding site interactions in endotoxic shock. (1983) (4)
- NALOXONE IN CEREBRAL ISCHAEMIA (1982) (4)
- ICI 174864, a putative delta opioid antagonist, reverses endotoxemic hypotension: pretreatment with dynorphin 1-13, A kappa agonist, blocks this action. (1984) (4)
- Endogeneous Opioids in the Pathophysiology of Shock: Sites of Action, Autonomic Involvement, and Receptor Interactions (1988) (4)
- Upregulation of the mu-noncompetitive delta binding site by chronic morphine administration: effect of preincubating membranes in 400 nM sodium chloride. (1986) (4)
- Cardiovascular responses to intrathecal vasopressin in conscious and anesthesized rats. (1989) (4)
- Interaction of beta-funaltrexamine with [3H]cycloFOXY binding in rat brain: further evidence that beta-FNA alkylates the opioid receptor complex. (1991) (4)
- Opiate Receptor Subtypes (1985) (4)
- The role of endogenous opioid peptides in the control of androgen levels in the male nonhuman primate. (1984) (4)
- Opioids and Stress: Effects Upon Nociception, Behavior, and Autonomic Function Following Electroconvulsive Shock, Circulatory Shock, or Central Nervous System Injury (1989) (4)
- NALOXONE IMPROVEMENT OF SHOCK PATHOPHYSIOLOGY: EVIDENCE FOR OPIATE RECEPTOR INVOLVEMENT (1980) (4)
- Verapamil reverses calcium cardiotoxicity. (1987) (4)
- Endorphins in shock and spinal injury; therapeutic effects of naloxone and thyrotropin-releasing hormone. (1983) (3)
- The pathogenesis of septic shock. (1984) (3)
- Endorphin-opiate interactions with neuroendocrine systems. (1979) (3)
- Endorphins in traumatic spinal injury. Pathophysiologic studies and clinical implications. (1981) (3)
- Endorphins and Thyrotropin Releasing Hormone in Shock and Trauma (1982) (3)
- Effects of naloxone and thyrotropin-releasing hormone on plasma catecholamines, corticosterone, and arterial pressure in normal and endotoxemic rats. (1986) (3)
- Neuroendocrine immunology: relevance to the management of critical illness. (1992) (3)
- Ultradian cortisol rhythms in monkeys: synchronized or not synchronized? (1978) (2)
- ENDORPHIN INVOLVEMENT IN THE PATHOPHYSIOLOGY OF SHOCK AND TRAUMA: THERAPEUTIC EFFECTS OF NALOXONE (1981) (2)
- Progress in opioid research. Proceedings of the 1986 International Narcotics Research Conference. (1986) (2)
- Central glucagon antagonizes morphine- and stress-induced antinociception in the mouse. (1986) (2)
- Endorphin-parasympathetic interactions in spinal shock. (1980) (2)
- ICI 154,129, a delta-opioid receptor antagonist raises seizure threshold in rats. (1984) (2)
- Electroencephalographic assessment of the role of delta receptors in opioid peptide - induced seizures. (1984) (2)
- Mu and delta opioid receptor interactions in a rat model of drug induced seizures. (1984) (2)
- Brain, Endocrine and Immune Interactions: Implications in Intensive Care (1989) (1)
- Neuroendocrine-immune interactions and their relevance to the pharmacology of critical care medicine. (1991) (1)
- HYPOCALCEMIA POTENTIATES EPINEPHRINE-STIMULATED HEPATIC GLUCONEOGENESIS IN NORMAL AND ENDOTOXEMIC RATS (1987) (1)
- GLUCAGON IS A UNIQUE CARDIOVASCULAR AGENT WITH ANTI-OPIATE ACTIVITY (1985) (1)
- Possible role of β-endorphin in heat adaptation (1979) (1)
- Naloxone decreases neurologic deficits in experimental aortic cross-clamping ischemia (1985) (1)
- Endorphins in Traumatic Spinal Injury (1981) (1)
- Evaluation of thyrotropin releasing hormone as a therapeutic intervention for endotoxemia (1990) (1)
- Ca and Sr influence on carbohydrate synthesis and composition in Protosiphon (1969) (1)
- The role of endogenous opiates in shock: introductory comments. (1983) (1)
- Enhancement of Tissue Oxygenation by Intracellular Introduction of Inositol Hexaphosphate by Flow Electroporation of Red Blood Cells (2002) (1)
- Role of Opioid Antagonists in the Therapy of Septic Shock (1989) (1)
- Méthodes de traitement du cancer (2009) (0)
- Endogenous Opioids and Opioid Antagonists in Endotoxic and Septic Shock: A Current Perspective (1992) (0)
- ENDOGENOUS OPIOID SYSTEMS AND AUTONOMIC FUNCTION (1984) (0)
- Prolactin promotes plasmacytoma tumor growth in vivo and in vitro (1985) (0)
- H6.2. Dual-Opioids™ (morphine+oxycodon) provide analgesia with reduced side effects in acute surgical pain (2009) (0)
- The Role of Endorphins in the Pathophysiology of Shock and the Therapeutic Benefit of Opiate Antagonists (1980) (0)
- f3-Endorphin: Pituitary andadrenal glands modulate itsaction (hypophysectomy/thermoregulation/antinociception/catalepsy/glucocorticoid) (1977) (0)
- Lerner B. Hinshaw, PhD, FCCM (1995) (0)
- FLOW ELECTROPORATION OF INOSITOL HEXAPHOSPHATE INTO ERYTHROCYTES ENHANCES TISSUE OXYGEN DELIVERY: 574 (1997) (0)
- Meta 2 — An Analysis of Meta-Analyses of Mediators in Septic Shock (2019) (0)
- B-endorphin: unique behavioral effects related to thermoregulation (1978) (0)
- QRxPharma - Breaking the Mould (2007) (0)
- Storing energy in chemical bonds - Strategies for electrochemical conversion of organic waste to petrochemicals and fuels (2019) (0)
- How Pharmacists Can Encourage the Disposal of Unused Prescriptions (2019) (0)
- Endorphins may function in heat adaptation ( thermoregulation (0)
- Site-directed affinity ligands as tools to study the phenomenology and mechanisms of morphine-induced upregulation of opioid receptors. (1989) (0)
- MEASUREMENT OF TOTAL CYTOKINE IN BLOOD AS A BIOLOGICAL RESPONSE MARKER.: 54 (1998) (0)
- Cells-Flowing direction Pre-loaded cells Peristaltic Pump Loading Chamber Loaded cells (2002) (0)
- 134; LIPID A INDUCES PROTECTION IN BALB/c MICE AGAINST INFECTION WITH AN AGGRESSIVE GRAM NEGATIVE PATHOGEN (1994) (0)
- Naloxone reduces renal blood flow in rabbit hemorrhagic shock (1984) (0)
- Pretreatment of rats with the irreversible mu-receptor antagonist, beta-FNA, fails to prevent naltrexone-induced upregulation of mu-opioid receptors. (1990) (0)
- Evidence for Involvement in the Postictal Effects (2006) (0)
- ACCELERATED Antiangiogenic Activity of Prostate-Specific Antigen (1999) (0)
- EFFECTIVE TREATMENT OF ACUTE CALCIUM CARDIOTOXICITY WITH VERAPAMIL IN RATS (1985) (0)
- Opioids and Other Neuropeptides: Functional Interactions with Autonomic Systems (1986) (0)
- Preparations and procedures for the treatment of cancer and hyperproliferative diseases (1994) (0)
- Thyrotropin releasing hormone: Effects in monkeys and dogs subjected to experimental circulatory shockm (1987) (0)
- Compositions et procedes de traitement du cancer et de maladies hyperproliferatives (1994) (0)
- ACCELERATED DISCOVERY Antiangiogenic Activity of Prostate-Specific Antigen (1999) (0)
- KEY MEDIATORS IN THE PATHOPHYSIOLOGY OF SHOCK AND SEPSIS (1995) (0)
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