J. wayne Streilein

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J. wayne Streilein

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Philosophy

J. wayne Streilein's Degrees

Doctorate Medicine Stanford University

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J. wayne Streilein's Published Works

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Published Works

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. (2004) (987)
Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. (1980) (960)
Ocular immune privilege: therapeutic opportunities from an experiment of nature (2003) (702)
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. (2005) (677)
Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor. (1991) (526)
Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. (1990) (460)
Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation (1983) (389)
Skin-associated lymphoid tissues (SALT): origins and functions. (1983) (359)
Ocular immune privilege: the eye takes a dim but practical view of immunity and inflammation (2003) (325)
Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. (2004) (324)
Unraveling Immune Privilege (1995) (310)
ORTHOTOPIC CORNEAL TRANSPLANTATION IN MICE—EVIDENCE THAT THE IMMUNOGENETIC RULES OF REJECTION DO NOT APPLY (1992) (301)
Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β (1992) (295)
The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help (1978) (276)
Induction of anterior chamber-associated immune deviation requires an intact, functional spleen (1981) (269)
Immunity causing blindness: five different paths to herpes stromal keratitis. (1997) (252)
Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision. (2006) (247)
TGF-beta promotes immune deviation by altering accessory signals of antigen-presenting cells. (1998) (243)
Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments. (1993) (240)
Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor. (1992) (237)
Corneal Lymphangiogenesis: Evidence, Mechanisms, and Implications for Corneal Transplant Immunology (2003) (231)
Corneal allografts fail to express Ia antigens (1979) (231)
Immune Response to Immunization via the Anterior Chamber of the Eye (1977) (229)
Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity (2004) (227)
Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor. (1994) (224)
Immune regulation and the eye: a dangerous compromise (1987) (222)
Thy-1 antigen-bearing dendritic cells populate murine epidermis. (1983) (221)
Graft-versus-Host reactions: a review. (1976) (216)
Loss and restoration of immune privilege in eyes with corneal neovascularization. (1996) (211)
ANTERIOR CHAMBER ASSOCIATED IMMUNE DEVIATION (ACAID): REGULATION, BIOLOGICAL RELEVANCE, AND IMPLICATIONS FOR THERAPY (2002) (205)
cis-urocanic acid suppression of contact hypersensitivity induction is mediated via tumor necrosis factor-alpha. (1992) (187)
Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. (1993) (185)
Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood. (1991) (184)
Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice. (1981) (184)
Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations. (1990) (182)
Time Course of Angiogenesis and Lymphangiogenesis After Brief Corneal Inflammation (2006) (181)
Lymphocyte traffic, T-cell malignancies and the skin. (1978) (179)
Neural Progenitor Cells Lack Immunogenicity and Resist Destruction as Allografts (2003) (178)
Immunobiology and privilege of neuronal retina and pigment epithelium transplants (2002) (177)
Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologic properties. (1980) (175)
Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis. (2004) (174)
In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes. (1989) (173)
Immune deviation in relation to ocular immune privilege. (1997) (167)
Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts. (1993) (157)
Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-borne signals that induce ACAID. (1991) (152)
Topical interleukin 1 receptor antagonist promotes corneal transplant survival. (1997) (151)
IL-6 antagonizes TGF-beta and abolishes immune privilege in eyes with endotoxin-induced uveitis. (2000) (150)
Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitrofluorobenzene sensitization. (1980) (146)
Induction and regulation of contact hypersensitivity by resident, bone marrow-derived, dendritic epidermal cells: Langerhans cells and Thy-1+ epidermal cells. (1986) (145)
Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens (1980) (144)
Light-induced migration of retinal microglia into the subretinal space. (2001) (143)
Evidence that retinal pigment epithelium functions as an immune-privileged tissue. (2000) (140)
On the mechanisms by which transforming growth factor‐β2 alters antigen‐presenting abilities of macrophages on T cell activation (1997) (136)
Depletion of epidermal langerhans cells and Ia immunogenicity from tape- stripped mouse skin (1982) (134)
Pigment epithelial growth factor suppresses inflammation by modulating macrophage activation. (2006) (133)
Analysis of immune deviation elicited by antigens injected into the subretinal space. (1998) (132)
Role of CD4+ T cells in immunobiology of orthotopic corneal transplants in mice. (1999) (132)
Characterization of the suppressor cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. (1985) (126)
Ultraviolet B light-induced alterations in epidermal Langerhans cells are mediated in part by tumor necrosis factor-alpha. (1990) (126)
Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor. (1998) (125)
Ocular disease induced in mice by anterior chamber inoculation of herpes simplex virus. (1984) (122)
By Altering Ocular Immune Privilege, Bone Marrow–derived Cells Pathogenically Contribute to DBA/2J Pigmentary Glaucoma (2003) (121)
Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells. (1990) (120)
Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms (2003) (115)
Calcitonin gene-related peptide is necessary for ultraviolet B-impaired induction of contact hypersensitivity. (1997) (115)
Anterior chamber associated immune deviation: the privilege of immunity in the eye. (1990) (114)
Immunosuppressive properties of tissues obtained from eyes with experimentally manipulated corneas. (1996) (113)
Thrombospondin Plays a Vital Role in the Immune Privilege of the Eye (2007) (113)
Alloantigens placed into the anterior chamber of the eye induce specific suppression of delayed-type hypersensitivity but normal cytotoxic T lymphocyte and helper T lymphocyte responses. (1983) (113)
Distinctive humoral immune responses following anterior chamber and intravenous administration of soluble antigen. Evidence for active suppression of IgG2-secreting B lymphocytes. (1990) (111)
Immune surveillance and sunlight-induced skin cancer. (1994) (109)
Iris Pigment Epithelium Expressing CD86 (B7-2) Directly Suppresses T Cell Activation In Vitro via Binding to Cytotoxic T Lymphocyte–associated Antigen 4 (2003) (108)
Inhibition of lymphocyte proliferation by aqueous humor. (1989) (108)
Does innate immune privilege exist? (2000) (105)
Aqueous humor induces transforming growth factor-beta (TGF-beta)-producing regulatory T-cells. (1997) (104)
Functional Dichotomy between Langerhans Cells that Present Antigen to Naive and to Memory/Effector T Lymphocytes (1990) (103)
Macrophages capable of inducing anterior chamber associated immune deviation demonstrate spleen-seeking migratory properties. (1992) (102)
The eye's view of antigen presentation. (2002) (102)
Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation. (1978) (101)
Immunoregulatory properties of bone marrow-derived cells in the iris and ciliary body. (1989) (100)
Effects of ultraviolet B light on cutaneous immune responses of humans with deeply pigmented skin. (1991) (97)
Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation induction. (1995) (97)
Hapten-specific tolerance induced by acute, low-dose ultraviolet B radiation of skin is mediated via interleukin-10. (1997) (95)
Suppression of experimental autoimmune uveitis in mice by induction of anterior chamber-associated immune deviation with interphotoreceptor retinoid-binding protein. (1992) (94)
Analysis of Immunomodulatory Activities of Aqueous Humor from Eyes of Mice with Experimental Autoimmune Uveitis1 (2000) (93)
Immunologic consequences of intraocular implantation of retinal pigment epithelial allografts. (1994) (92)
Characterization of cell-mediated immune responses elicited by orthotopic corneal allografts in mice. (1995) (92)
Immune privilege and suppression of immunogenic inflammation in the anterior chamber of the eye. (1991) (90)
Anterior chamber-associated immune deviation, ocular immune privilege, and orthotopic corneal allografts. (1999) (87)
Regional immunity and ocular immune privilege. (1999) (86)
Transplantation immunology of the anterior chamber of the eye. II. Immune response to allogeneic cells. (1975) (86)
Langerhans cells: sentinels of skin associated lymphoid tissue. (1980) (86)
Immunosuppressive properties of the pigmented epithelial cells and the subretinal space. (2007) (86)
Systemic Immune Deviation in the Brain That Does Not Depend on the Integrity of the Blood-Brain Barrier1 (2000) (84)
Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products. (1991) (84)
Alpha-melanocyte-stimulating hormone suppresses antigen-stimulated T cell production of gamma-interferon. (1994) (84)
Ocular immune privilege and the Faustian dilemma. The Proctor lecture. (1996) (83)
Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye. (1992) (82)
Immunological non-responsiveness and acquisition of tolerance in relation to immune privilege in the eye (1995) (82)
Tolerance or hypersensitivity to 2,4-dinitro-1-fluorobenzene: the role of Langerhans cell density within epidermis. (1980) (82)
Relationship between ultraviolet radiation-induced immunosuppression and carcinogenesis. (1994) (82)
Immune privilege, T-cell tolerance, and tissue-restricted autoimmunity. (1997) (82)
Minor H, rather than MHC, alloantigens offer the greater barrier to successful orthotopic corneal transplantation in mice. (1996) (82)
Circuits and signals of the skin-associated lymphoid tissues (SALT). (1985) (81)
Vitamin C abrogates the deleterious effects of UVB radiation on cutaneous immunity by a mechanism that does not depend on TNF-alpha. (1997) (80)
Langerhans cells: antigen presenting cells of the epidermis. (1984) (79)
Interleukin-1 receptor antagonist suppresses Langerhans cell activity and promotes ocular immune privilege. (1998) (79)
Studies of tumor-infiltrating lymphocytes from a human choroidal melanoma. (1991) (78)
Analysis of cytotoxic T cell responses to intracameral allogeneic tumors. (1989) (77)
Immune Privilege and Immunogenicity Reside among Different Layers of the Mouse Cornea (2000) (77)
Interleukin 1 receptor antagonist suppresses allosensitization in corneal transplantation. (1998) (74)
Autoimmunity in the eye and its regulation. (1994) (74)
Murine orthotopic corneal transplantation in high-risk eyes. Rejection is dictated primarily by weak rather than strong alloantigens. (1997) (74)
Lymphocyte adhesion to psoriatic dermal endothelium is mediated by a tissue-specific receptor/ligand interaction. (1988) (74)
Alterations in cytokine production following intraocular injection of soluble protein antigen: impairment in IFN-gamma and induction of TGF-beta and IL-4 production. (1998) (74)
Immunobiology of Langerhans cells on the ocular surface. I. Langerhans cells within the central cornea interfere with induction of anterior chamber associated immune deviation. (1987) (73)
Tumor necrosis factor-alpha and ultraviolet B light have similar effects on contact hypersensitivity in mice. (1990) (72)
Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation. (1982) (72)
FACS purification of bone marrow-derived epidermal populations in mice: Langerhans cells and Thy-1+ dendritic cells. (1985) (71)
Eye-derived cytokines and the immunosuppressive intraocular microenvironment: a review. (1992) (71)
Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact. (2000) (70)
On the extraordinary capacity of allogeneic epidermal Langerhans cells to prime cytotoxic T cells in vivo. (1989) (70)
Ocular immune privilege and the impact of intraocular inflammation. (2002) (70)
A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation. (1998) (70)
Evidence that peritoneal exudate cells cultured with eye-derived fluids are the proximate antigen-presenting cells in immune deviation of the ocular type. (1993) (69)
Expression of Thrombospondin in TGFβ-Treated APCs and Its Relevance to Their Immune Deviation-Promoting Properties1 (2002) (66)
Using Tolerance Induced Via the Anterior Chamber of the Eye to Inhibit Th2-Dependent Pulmonary Pathology1 (2002) (66)
Two Waves of Virus Following Anterior Chamber Inoculation of HSV-1 (1987) (66)
Sunlight and skin-associated lymphoid tissues (SALT): if UVB is the trigger and TNF alpha is its mediator, what is the message? (1993) (64)
UVB radiation and DNFB skin painting induce suppressor cells universally in mice. (1990) (63)
Immunobiology of Langerhans cells on the ocular surface. II. Role of central corneal Langerhans cells in stromal keratitis following experimental HSV-1 infection in mice. (1989) (63)
Imposing deviant immunity on the presensitized state. (1994) (63)
Epithelium-deficient corneal allografts display immune privilege beneath the kidney capsule. (2000) (63)
Thy-1 antigen-bearing dendritic cells in murine epidermis are derived from bone marrow precursors. (1984) (62)
Neonatal Tolerance: Towards an Immunogenetic Definition of Self (1979) (62)
Deleterious effects of cis-urocanic acid and UVB radiation on Langerhans cells and on induction of contact hypersensitivity are mediated by tumor necrosis factor-alpha. (1992) (62)
Neonatal tolerance of H-2 alloantigens. Procuring graft acceptance the "old-fashioned" way. (1991) (61)
Tumor necrosis factor alpha polymorphism correlates with deleterious effects of ultraviolet B light on cutaneous immunity. (1993) (60)
Origin and function of Thy-1+ dendritic epidermal cells in mice. (1985) (60)
Thrombospondin orchestrates the tolerance-promoting properties of TGFbeta-treated antigen-presenting cells. (2006) (60)
Langerhans cell function dictates induction of contact hypersensitivity or unresponsiveness to DNFB in Syrian hamsters. (1981) (60)
FOXP3+ CD25+ T Cells Induced by Ocular Pigment Epihelium Display Regulatory Phenotype and Aquire Regulatory Functions (2006) (60)
Immune privilege extended to allogeneic tumor cells in the vitreous cavity. (1991) (59)
Spontaneous corneal hem- and lymphangiogenesis in mice with destrin-mutation depend on VEGFR3 signaling. (2005) (59)
Dynamics of donor cell persistence and recipient cell replacement in orthotopic corneal allografts in mice. (2001) (59)
Neural Control of Ocular Immune Privilege (2000) (58)
A substance p agonist acts as an adjuvant to promote hapten-specific skin immunity. (1998) (57)
Haptoglobin is a natural regulator of Langerhans cell function in the skin. (2000) (57)
Failure of infiltrating precursor cytotoxic T cells to acquire direct cytotoxic function in immunologically privileged sites. (1990) (56)
B7+ Iris Pigment Epithelium Induce CD8+ T Regulatory Cells; Both Suppress CTLA-4+ T Cells12 (2006) (56)
Immunobiology and immunopathology of corneal transplantation. (1999) (55)
Effects of experimental ocular inflammation on ocular immune privilege. (1999) (55)
New thoughts on the immunology of corneal transplantation (2003) (55)
Neonatal tolerance induction across regions of H-2 complex. (1977) (55)
In vitro generation of regulatory CD8+ T cells similar to those found in mice with anterior chamber-associated immune deviation. (2000) (54)
Intracamerally induced concomitant immunity: mice harboring progressively growing intraocular tumors are immune to spontaneous metastases and secondary tumor challenge. (1983) (54)
AN ANALYSIS OF GRAFT-VERSUS-HOST DISEASE IN SYRIAN HAMSTERS (1970) (54)
Peripheral tolerance induction: lessons from immune privileged sites and tissues. (1996) (54)
Toxic epidermal necrolysis and homologous disease in hamsters. (1968) (53)
Thrombospondin plays a vital role in the immune privilege of the eye. 2005. (2005) (53)
CD8+ T regulatory cells use a novel genetic program that includes CD103 to suppress Th1 immunity in eye-derived tolerance. (2006) (53)
CTLA-4+CD8+ T Cells That Encounter B7-2+ Iris Pigment Epithelial Cells Express Their Own B7-2 to Achieve Global Suppression of T Cell Activation1 (2004) (51)
T-lymphocyte-activating properties of epidermal antigen-presenting cells from normal and psoriatic skin: evidence that psoriatic epidermal antigen-presenting cells resemble cultured normal Langerhans cells. (1991) (51)
HOMOGRAFT SENSITIVITY REACTIONS IN IRRADIATED HAMSTERS. (1965) (51)
Detection of minor alloantigen-specific cytotoxic T cells after rejection of murine orthotopic corneal allografts: evidence that graft antigens are recognized exclusively via the "indirect pathway". (1999) (51)
Mice with Th2-biased immune systems accept orthotopic corneal allografts placed in "high risk" eyes. (1999) (50)
Genetic basis of the effects of ultraviolet light B on cutaneous immunity. Evidence that polymorphism at the Tnfa and Lps loci governs susceptibility (2004) (50)
High and low doses of haptens dictate whether dermal or epidermal antigen‐presenting cells promote contact hypersensitivity (1997) (50)
Role of donor-specific cytotoxic T cells in rejection of corneal allografts in normal and high-risk eyes. (1996) (50)
Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 2. Generation of TGF-beta-producing regulatory T cells. (2000) (50)
Inhibition of antigen-stimulated effector T cells by human cerebrospinal fluid. (1996) (50)
Xenoreactive CD4+ T cells and acute rejection of orthotopic guinea pig corneas in mice. (2000) (50)
Comparison of effects of transforming growth factor-beta and cyclosporin A on antigen-presenting cells of blood and epidermis. (1991) (50)
B7+ iris pigment epithelial cells convert T cells into CTLA-4+, B7-expressing CD8+ regulatory T cells. (2006) (49)
Failed antigen presentation after UVB radiation correlates with modifications of Langerhans cell cytoskeleton. (1996) (49)
Induction of encephalitis in SJL mice by intranasal infection with herpes simplex virus type 1: a possible model of herpes simplex encephalitis in humans. (1991) (49)
Langerhans cells: functional aspects revealed by in vivo grafting studies. (1980) (48)
Aqueous humor factors and their effect on the immune response in the anterior chamber. (1990) (48)
Cytotoxic T cells play no essential role in acute rejection of orthotopic corneal allografts in mice. (2001) (47)
TGF-β Promotes Immune Deviation by Altering Accessory Signals of Antigen-Presenting Cells (1998) (46)
Evidence that ultraviolet B radiation induces tolerance and impairs induction of contact hypersensitivity by different mechanisms. (1994) (46)
Immune privilege is extended, then withdrawn, from allogeneic tumor cell grafts placed in the subretinal space. (1999) (46)
Local ultraviolet B irradiation impairs contact hypersensitivity induction by triggering release of tumor necrosis factor-alpha from mast cells. Involvement of mast cells and Langerhans cells in susceptibility to ultraviolet B. (1999) (46)
Induction of donor-specific ACAID can prolong orthotopic corneal allograft survival in "high-risk" eyes. (1997) (45)
Fate of orthotopic corneal allografts in C57BL/6 mice. (1998) (45)
On the Ia immunogenicity of mouse corneal allografts infiltrated with Langerhans cells. (1984) (45)
ANALYSIS OF ANTIBODY PRODUCTION INDUCED BY ALLOGENEIC TUMOR CELLS INOCULATED INTO THE ANTERIOR CHAMBER OF THE EYE (1982) (45)
Studies of contact hypersensitivity induction in mice with optimal sensitizing doses of hapten. (1993) (45)
Role of recipient epithelium in promoting survival of orthotopic corneal allografts in mice. (2001) (44)
Heterotopic corneal grafting in mice: a new approach to the study of corneal alloimmunity. (1982) (44)
Evidence for antigen-specific immune deviation in patients with acute retinal necrosis. (2001) (44)
Analysis of in vivo regulatory properties of T cells activated in vitro by TGFbeta2-treated antigen presenting cells. (2000) (43)
UNCONVENTIONAL REJECTION OF NEURAL RETINAL ALLOGRAFTS IMPLANTED INTO THE IMMUNOLOGICALLY PRIVILEGED SITE OF THE EYE (1995) (43)
Skin-associated lymphoid tissue. (1989) (42)
Fresh and cultured Langerhans cells display differential capacities to activate hapten-specific T cells. (1993) (42)
Induction of anterior chamber-associated immune deviation by corneal allografts placed in the anterior chamber. (1997) (40)
Ia antigens and epidermal Langerhans cells. (1980) (40)
Detection of donor-derived cells by polymerase chain reaction in neonatally tolerant mice. Microchimerism fails to predict tolerance. (1995) (40)
Immunoregulatory mechanisms of the eye (1999) (40)
Tumour necrosis factor-alpha mediates ultraviolet light B-enhanced expression of contact hypersensitivity. (1992) (39)
Langerhans cells, orthotopic corneal allografts, and direct and indirect pathways of T-cell allorecognition. (2000) (39)
Contribution of microglia as passenger leukocytes to the fate of intraocular neuronal retinal grafts. (1998) (39)
Presence of Langerhans cells in the central cornea linked to the development of ocular herpes in mice. (1992) (39)
ICAM-1 deficiency suppresses host allosensitization and rejection of MHC-disparate corneal transplants. (2000) (38)
Intraocular injection of class II-restricted peptide induces an unexpected population of CD8 regulatory cells. (1996) (38)
Anterior chamber-associated immune deviation induced by soluble antigens. (1989) (37)
Immunologic privilege in the eye and the fetus. (1987) (37)
Suppressive and enhancing effects of ultraviolet B radiation on expression of contact hypersensitivity in man. (1995) (37)
Unusual numbers and distribution of Langerhans cells in skin with unique immunologic properties. (1980) (37)
The differing patterns of antigen release and local retention following anterior chamber and intravenous inoculation of soluble antigen. Evidence that the eye acts as an antigen depot. (1989) (37)
Histocompatibility Testing 1965 (1966) (36)
Characterization of the immunogenetic basis of ultraviolet-B light effects on contact hypersensitivity induction. (1994) (36)
Local and systemic consequences of acute, low‐dose ultraviolet B radiation are mediated by different immune regulatory mechanisms (1994) (35)
Hapten‐specific tolerance induced by acute, low‐dose ultraviolet B radiation of skin requires mast cell degranulation (2001) (35)
Induction of eye-derived tolerance does not depend on naturally occurring CD4+CD25+ T regulatory cells. (2006) (34)
Role of dermal cells from normal and ultraviolet B-damaged skin in induction of contact hypersensitivity and tolerance. (1994) (34)
ACAID induced by allogeneic corneal tissue promotes subsequent survival of orthotopic corneal grafts. (2000) (34)
Immune Privilege Persists in Eyes with Extreme Inflammation Induced by Intravitreal LPS (2007) (34)
Acute rejection of orthotopic corneal xenografts in mice depends on CD4(+) T cells and self-antigen-presenting cells. (2001) (33)
A critical role for ACAID in the distinctive pattern of retinitis that follows anterior chamber inoculation of HSV-1. (1987) (32)
Hapten-specific tolerance promoted by calcitonin gene-related peptide. (2000) (32)
Interrelationship between ultraviolet light and recurrent herpes simplex infections in man. (1994) (32)
Immunologic privilege of the eye (2004) (32)
Survival in high-risk eyes of epithelium-deprived orthotopic corneal allografts reconstituted in vitro with syngeneic epithelium. (2003) (32)
B7+ iris pigment epithelium induce CD8+ T regulatory cells; both suppress CTLA-4+ T cells (2006) (31)
Induction of anterior chamber-associated immune deviation (ACAID) by allogeneic intraocular tumors does not require splenic metastases. (1982) (31)
Retinitis and deviant immune responses following intravitreal inoculation of HSV-1. (1987) (30)
Corneal transplantation in antibody-deficient hosts. (1999) (30)
Transplantation immunology of the anterior chamber of the eye. I. An intra-ocular graft-vs-host reaction (immunogenic anterior uveitis). (1975) (30)
Intravenously injected, TNP-derivatized, Langerhans cell-enriched epidermal cells induce contact hypersensitivity in Syrian hamsters. (1985) (30)
Interleukin-1 receptor antagonist therapy and induction of anterior chamber-associated immune deviation-type tolerance after corneal transplantation. (2000) (30)
Herpetic stromal keratitis in mice: less reversibility in the presence of Langerhans cells in the central cornea. (1991) (30)
Mechanisms of protection against herpes simplex virus type 1-induced retinal necrosis by in vitro-activated T lymphocytes (1991) (30)
Functional cytotoxic T cells are associated with focal lesions in the brains of SJL mice with experimental herpes simplex encephalitis. (1994) (29)
Effect of local macrophage depletion on cellular immunity and tolerance evoked by corneal allografts (2003) (28)
The role of minor histocompatibility alloantigens in penetrating keratoplasty. (2003) (28)
Regulation of the immune response within privileged sites. (1994) (28)
Ultraviolet B-exposed and soluble factor-pre-incubated epidermal Langerhans cells fail to induce contact hypersensitivity and promote DNP-specific tolerance. (1997) (28)
Failure of in vitro assays to predict accurately the existence of neonatally induced H-2 tolerance. (1989) (28)
In-vivo impaired T helper 1 cell development in submandibular lymph nodes due to IL-12 deficiency following antigen injection into the anterior chamber of the eye (2000) (28)
Reduction in number and morphologic alterations of Langerhans cells after UVB radiation in vivo are accompanied by an influx of monocytoid cells into the epidermis. (1998) (27)
Histopathologic study of herpes virus-induced retinitis in athymic BALB/c mice: evidence for an immunopathogenic process. (1989) (27)
Modification of the cytotoxic T cell repertoire in neonatal tolerance. Evidence for preferential survival of cells with low avidity for tolerogen. (1987) (27)
Analysis of dose response of trinitrochlorobenzene contact hypersensitivity induction in mice: pretreatment with cyclophosphamide reveals an optimal sensitizing dose. (1990) (26)
Regulators of immunological responses in the cornea and the anterior chamber of the eye (1995) (26)
Blood-borne signals that induce anterior chamber-associated immune deviation after intracameral injection of antigen. (1997) (26)
Anterior chamber-associated immune deviation elicited via primate eyes. (1993) (26)
Molecular basis of ACAID. (1997) (26)
Distinctive distribution of HLA class II presenting and bone marrow derived cells in the anterior segment of human eyes. (1992) (26)
Mediators of protection against lethal systemic vesicular stomatitis virus infection in hamsters: defective interfering particles, polyinosinate-polycytidylate, and interferon (1982) (25)
Neural Influences on Induction of Contact Hypersensitivity (1999) (25)
Role of tumor necrosis factor receptors TNFR-I (P55) and TNFR-II (P75) in corneal transplantation. (1999) (25)
Description of phenotypically distinct T-lymphocyte subsets which mediate helper/DTH and cytotoxic functions in the Syrian hamster. (1985) (25)
Use of ACAID to suppress interphotoreceptor retinoid binding protein-induced experimental autoimmune uveitis. (1992) (25)
CUTANEOUS HYPERSENSITIVITY REACTIONS TO CELLULAR ISOANTIGENS IN RATS (1967) (24)
Evidence that T-Helper Type 2 Cell-Derived Cytokines and Eosinophils Contribute to Acute Rejection of Orthotopic Corneal Xenografts in Mice (2005) (24)
Influence of alpha-melanocyte stimulating hormone on induction of contact hypersensitivity and tolerance. (1994) (24)
A CIITA‐independent pathway that promotes expression of endogenous rather than exogenous peptides in immune‐privileged sites (2004) (24)
Vesicular stomatitis virus can establish persistent infections in Syrian hamsters. (1982) (24)
Neonatally tolerant mice fail to react against virus-infected tolerated cells (1977) (24)
Lymphocyte recognition of psoriatic endothelium: evidence for a tissue-specific receptor/ligand interaction. (1989) (24)
Genetic basis of ultraviolet-B effects on contact hypersensitivity (1988) (24)
An ultraviolet B radiation protocol for complete depletion of human epidermal Langerhans cells. (1989) (23)
T cell immunity induced by allogeneic microglia in relation to neuronal retina transplantation. (1999) (23)
Tissue barriers, immunosuppressive microenvironments, and privileged sites: the eye's point of view. (1993) (22)
Ocular injection of retinal S antigen: suppression of autoimmune uveitis. (1989) (22)
IMMUNOGENETIC RELATIONSHIPS AMONG GENETICALLY DEFINED, INBRED DOMESTIC SYRIAN HAMSTER STRAINS (1980) (22)
Immunosuppressive properties of cultured human cornea and ciliary body in normal and pathological conditions. (1995) (22)
T cells recognize minor histocompatibility antigens on H-2 allogeneic cells (1979) (22)
Hamster Immune Responses in Infectious and Oncologic Diseases (2012) (21)
Neonatal tolerance of H-2 alloantigens. I. I region modulation of tolerogenic potential of K and D antigens (1980) (21)
Role of inflammatory cytokines in induction of anterior chamber-associated immune deviation. (1998) (21)
Role of suppressor T cells in herpes simplex virus-induced immune deviation (1984) (21)
A new concept of skin-associated lymphoid tissue (SALT): UVB light impaired cutaneous immunity reveals a prominent role for cutaneous nerves. (1999) (21)
Characterization of specific T helper cell activity in mice bearing alloantigenic tumors in the anterior chamber of the eye (1991) (21)
Immunogenetic factors in skin cancer. (1991) (21)
Naïve, hapten-specific human T lymphocytes are primed in vitro with derivatized blood mononuclear cells. (1998) (21)
Cumulative sunlight exposure and the risk of developing skin cancer in Florida. (1992) (21)
Immune responses elicited by transplantation and tissue-restricted antigens expressed on retinal tissues implanted subconjunctivally. (1991) (21)
Histopathologic characteristics of two forms of experimental herpes simplex virus retinitis. (1987) (20)
ACTIVE CLONAL DELETION IN NEONATAL H‐2 TOLERANCE * (1982) (20)
CD8+ T cell-mediated delayed rejection of orthotopic guinea pig cornea grafts in mice deficient in CD4+ T cells. (2003) (20)
Tolerance to class II major histocompatibility complex molecules is maintained in the presence of endogenous, interleukin-2-producing, tolerogen-specific T lymphocytes. (1987) (20)
Influence of splenectomy on first set rejection reactions of C57BL/6 females to male skin isografts (1977) (20)
Induction of anterior chamber-associated immune deviation with lymphoreticular allogeneic cells. (1995) (20)
Infiltration and accumulation of precursor cytotoxic T-cells increase with time in progressively growing ocular tumors. (1991) (20)
Immune response to acute virus infection in the Syrian hamster. II. Studies on the identity of virus-induced cytotoxic effector cells. (1981) (19)
EVIDENCE THAT I‐E‐NEGATIVE MICE RESISTANT TO NEONATAL H‐2 TOLERANCE INDUCTION DISPLAY UBIQUITOUS THYMIC CLONAL DELETION OF DONOR‐REACTIVE T CELLS1 (1993) (19)
Adoptive transfer of immunity to intraocular tumors in mice. (1984) (19)
Immune privilege persists in eyes with extreme inflammation induced by intravitreal LPS (2001) (19)
Regulation of ocular immune responses (1997) (19)
INDUCTION OF H‐2‐RESTRICTED CONTACT HYPERSENSITIVITY BY HAPTEN‐DERIVATIZED SKIN GRAFTS: Evidence That the Immunogenic Signal Includes H‐2 Determinants Derived From the Skin (1984) (19)
Neonatal tolerance to K and D region alloantigens of H-2 complex: I-J region requirements. (1979) (19)
Genetic mapping and physical cloning of UVB susceptibility region in mice. (1999) (19)
Vulnerability of allogeneic retinal pigment epithelium to immune T-cell-mediated damage in vivo and in vitro. (2004) (19)
Protection of mice from herpes simplex virus-induced retinitis by in vitro-activated immune cells (1989) (19)
Local cellular defenses in influenza-infected lungs. (1985) (19)
Studies of delayed systemic effects of ultraviolet B radiation (UVR) on the induction of contact hypersensitivity, 2. Evidence that interleukin‐10 from UVR‐treated epidermis is the critical mediator (2000) (19)
Local T helper cell signals by lymphocytes infiltrating intraocular tumors. (1992) (18)
Studies on delayed systemic effects of ultraviolet B radiation on the induction of contact hypersensitivity, 3. Dendritic cells from secondary lymphoid organs are deficient in interleukin‐12 production and capacity to promote activation and differentiation of T helper type 1 cells (2000) (18)
Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation. (1990) (18)
Immunology of ocular tumours. (1999) (18)
INDUCTION OF DELAYED HYPERSENSITIVITY TO ALLOANTIGENS COINJECTED WITH LANGERHANS CELLS INTO THE ANTERIOR CHAMBER OF THE EYE ABROGATION OF ANTERIOR CHAMBER‐ASSOCIATED IMMUNE DEVIATION (1989) (18)
Allogeneic Neonatal Neuronal Retina Grafts Display Partial Immune Privilege in the Subcapsular Space of the Kidney1 (2002) (18)
AN ANALYSIS OF THE GENETIC REQUIREMENTS FOR DELAYED CUTANEOUS HYPERSENSITIVITY REACTIONS TO TRANSPLANTATION ANTIGENS IN MICE (1970) (18)
Sensitizing capacity of Langerhans' cells obtained from ultraviolet-B-exposed murine skin. (1995) (17)
Chemokine gene expression in iris-ciliary body during experimental autoimmune uveoretinitis (2002) (17)
ALLOANTIGEN PRESENTATION TO THE ANTERIOR CHAMBER OF THE EYE SUBVERTS SPECIFIC IN VITRO CELL‐MEDIATED IMMUNE RESPONSES (1982) (17)
Pathologic lesions of GVH disease in hamsters: antigenic target versus 'innocent bystander'. (1972) (17)
Thy-1 antigen is present on B and T lymphocytes of the Syrian hamster. (1983) (17)
Genetic analysis of resistance to lethal infections of vesicular stomatitis virus in Syrian hamsters (1981) (17)
Lymphoma allografts abrogate immune privilege within the anterior chamber of the eye. (1986) (17)
Hypothesis: nonspecific polyclonal activation of memory B cells by antigen as a mechanism for the preservation of long term immunologic anamnesis. (1978) (16)
Role of F4/80+ cells during induction of hapten-specific contact hypersensitivity. (1995) (16)
Role of phagocytic macrophages in induction of contact hypersensitivity and tolerance by hapten applied to normal and ultraviolet B-irradiated skin. (1994) (16)
Immunogenetic basis for immunologic privilege in the anterior chamber of the eye (2004) (16)
Effect of intraocular gamma-interferon on immunoregulatory properties of iris and ciliary body cells. (1992) (16)
Histopathologic analysis of experimental autoimmune uveitis attenuated by intracameral injection of S-antigen. (1989) (16)
Aqueous Humor Induces Transforming Growth Factor-β (TGF-β)-Producing Regulatory T-Cells (2007) (16)
ANALYSIS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN SYRIAN HAMSTERS: I. SKIN GRAFT REJECTION, GRAFT‐VERSUS-HOST REACTIONS, MIXED LYMPHOCYTE REACTIONS, AND IMMUNE RESPONSE GENES IN INBRED STRAINS (1977) (16)
Monoclonal antibodies to hamster class II MHC molecules distinguish T and B cells. (1983) (16)
Characterization of cytotoxic cells in mice rendered neonatally tolerant of MHC alloantigens: evidence for repertoire modification. (1987) (15)
Speculations on the immunopathogenesis of psoriasis: T-cell violation of a keratinocyte sphere of influence. (1990) (15)
Immunobiology of xenogeneic cornea grafts in mouse eyes. II. Immunogenicity of xenogeneic cornea tissue grafts implanted in anterior chamber of mouse eyes. (2000) (15)
Analysis of neonatally induced tolerance of H-2 alloantigens. I. Adoptive transfer indicates that tolerance of class I and class II antigens is maintained by distinct mechanisms. (1981) (15)
Immunology of the skin and the eye. (1996) (15)
Recovery of Activated Cytotoxic T Cells from Minor H Incompatible Tumor Graft Rejection Sites (1989) (15)
AN ANALYSIS OF GRAFT-VERSUS-HOST DISEASE IN SYRIAN HAMSTERS (1970) (14)
Neonatal tolerance of H-2 alloantigens. II. I region dependence of tolerance expressed to K and D antigens (1980) (14)
Anterior chamber‐associated immune deviation‐inducing cells activate T cells, and rescue them from antigen‐induced apoptosis (1999) (14)
Contact hypersensitivity, humoral immunity, and specific unresponsiveness can be induced in Syrian hamsters with simple haptens. (1980) (14)
Comparison of alloimmunogenicity of Langerhans cells and keratinocytes from mouse epidermis. (1987) (14)
IMMUNE PRIVILEGE TO MHC‐DISPARATE TUMOR GRAFTS IN THE ANTERIOR CHAMBER OF THE EYE: I. QUANTITATIVE ANALYSIS OF INTRAOCULAR TUMOR GROWTH AND THE CORRESPONDING DELAYED HYPERSENSITIVITY RESPONSE (1989) (14)
In vitro culture allows splenic dendritic cells to reach their full potential for T-cell activation. (1993) (14)
ANALYSIS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN SYRIAN HAMSTERS: II. LINKAGE Studies (1978) (14)
A relationship between varicella-zoster virus-specific delayed hypersensitivity and varicella-zoster virus-induced anterior uveitis. (2002) (13)
Immunity and immune privilege elicited by autoantigens expressed on syngeneic neonatal neural retina grafts. (1992) (13)
Polymorphisms in the tumor necrosis factor (TNF) genes are associated with susceptibility to effects of ultraviolet-B radiation on induction of contact hypersensitivity. (2001) (13)
Evidence that precursor cytotoxic T cells mediate acute necrosis in HSV-1-infected retinas. (1991) (13)
Induction of anterior chamber associated immune deviation in rats receiving intracameral injections of retinal S antigen. (1988) (13)
Syrian hamsters express two monomorphic class I major histocompatibility complex molecules (2004) (13)
ANALYSIS OF GRAFT-VERSUS-HOST DISEASE IN SYRIAN HAMSTERS (1972) (13)
Cellular mechanisms that maintain neonatally-induced tolerance of class II alloantigens. Evidence that factor-mediated suppression silences cytotoxic T cell activity. (1994) (13)
ACAID requires early replication of HSV-1 in the injected eye. (1991) (13)
Mechanisms of neonatal transplantation tolerance. (1987) (13)
CD95 ligand expression on corneal epithelium and endothelium influences the fates of orthotopic and heterotopic corneal allografts in mice. (2004) (13)
Histopathologic analysis of intraocular allogeneic tumors in mice. (1985) (12)
EFFECTS OF SPLENECTOMY AND SENDAI VIRUS INFECTION ON REJECTION OF MALE SKIN ISOGRAFTS BY PATHOGEN‐FREE C57BL/6 FEMALE MICE (1981) (12)
Analysis of effects of ultraviolet B radiation on induction of primary allergic reactions. (1992) (12)
Specific lymphocyte-endothelial cell interactions regulate migration into lymph nodes, Peyer's patches, and skin. (1988) (12)
Sunlight and skin-associated lymphoid tissues (SALT) : if UVB is the trigger and TNFα is its mediator, what is the message ? : Connective tissue diseases and the skin (1993) (11)
Differential distribution of Langerhans cells in organ culture of human skin. (1982) (11)
Immunosuppressive properties of tissues of the ocular anterior segment. (1996) (11)
[Angiogenesis and lymphangiogenesis in the cornea. Pathogenesis, clinical implications and treatment options]. (2003) (11)
The biochemical characterization of Syrian hamster cell-surface alloantigens (1978) (11)
Evidence that active suppression contributes to the success of H-2-incompatible orthotopic corneal allografts in mice. (1993) (11)
Characterization of donor chimerism, alloreactive host T cells and memory cell development in thymi from mice resistant to neonatal transplantation tolerance. (1995) (11)
Transplantation tolerance: clonal deletion, active suppression, or both? (1981) (11)
Virus-specific DTH prevents contralateral retinitis following intracameral inoculation of HSV-2. (1987) (11)
Effects of chloroquine on antigen-presenting functions of epidermal cells from normal and psoriatic skin. (1992) (11)
SALT: Skin-Associated Lymphoid Tissues (1983) (11)
ANALYSIS OF PRIMED DONOR-SPECIFIC T CELLS IN RECIPIENT MICE BEARING ORTHOTOPIC CORNEAL ALLOGRAFTS1 (2000) (11)
Neonatal transplantation tolerance is associated with a systemic reduction in memory cells, altered chimeric cell phenotype, and modified eicosanoid and cytokine production. (1996) (11)
Neural Progenitor Cells Lack Immunogenicity and Resist Destruction as Allografts (2007) (10)
MHC Class I and II Antigens as Targets of Rejection in Penetrating Keratoplasty in Low- and High-Risk Mouse Eyes (2005) (10)
TERMINATION OF IMMUNE PRIVILEGE IN THE ANTERIOR CHAMBER OF THE EYE WHEN TUMOR‐INFILTRATING LYMPHOCYTES ACQUIRE CYTOLYTIC FUNCTION (1991) (10)
Immunobiology of xenogeneic cornea grafts in mouse eyes. I. Fate of xenogeneic cornea tissue grafts implanted in anterior chamber of mouse eyes. (2000) (10)
Analysis of Immune Privilege in Eyes with Mycobacteria tuberculosa Adjuvant-Induced Uveitis (2005) (10)
On the anomalous nature of the major histocompatibility complex in Syrian hamsters, Hm-1. (1983) (9)
Development and ontogeny of hamster T cell subpopulations. (1986) (9)
DONOR‐SPECIFIC SKIN TRANSPLANTS ACTIVATE ALLODESTRUCTIVE T CELLS IN MICE RESISTANT TO NEONATAL H‐2 TOLERANCE INDUCTION1 (1993) (9)
Promotion of syngeneic intraocular tumor growth in mice by anterior chamber-associated immune deviation. (1983) (9)
Transplantation immunobiology in relation to neural grafting: Lessons learned from immunologic privilege in the eye (1988) (9)
Incomplete activation of lymphokine-producing T cells by alloantigenic intraocular tumours in anterior chamber-associated immune deviation. (1993) (9)
In vitro suppression of cytotoxic T cell generation by lymphocytes from mice rendered neonatally tolerant of class II MHC alloantigens. (1991) (9)
Immunogenetics of Sunlight‐Induced Skin Cancer (1996) (9)
Ocular immune privilege in the immunosuppressive intraocular microenvironment. (1995) (9)
The irradiated hamster test. A new method of donor selection for homotransplantation in man. (1966) (8)
A common pathogenesis for the lesions of graft-versus-host disease. (1971) (8)
Regulation of Langerhans cell function via blood borne factor(s). (1996) (8)
Transplantation immunity and delayed cutaneous hypersensitivity reactions in dogs. (1967) (8)
Vascular Endothelial Growth Factor Receptor-3 Mediates Induction of Corneal Alloimmunity (2007) (8)
Immune privilege in the eye: an evolutionary adaptation. (1994) (8)
Syrian hamsters express diverse MHC class I gene products. (1991) (8)
Effects of UV Radiation on Immune Responses in Animals (1983) (8)
Induction of anterior chamber-associated immune deviation (acaid) does not require splenic metastasis of allogenic intraocular tumors. Abstr. (1982) (8)
Cellular mechanisms that maintain neonatally-induced tolerance of class II alloantigens. Evidence that precursor cytotoxic T cells are present but silenced. (1994) (8)
Complete elimination ('cure') of progressively growing intraocular tumors by local injection of tumor-specific CD8+ T lymphocytes. (1993) (8)
Regional Specialization in Antigen Presentation (1986) (8)
Studies on the repopulation of Langerhans cells in partial-thickness wounds. Air exposed and occlusively dressed. (1993) (8)
Genetic factors in immunosuppression: precise genetic evidence that polymorphism of TNF-alpha dictates UVB-susceptibility in mice. (2000) (8)
Tumor necrosis factor‐alpha impairs contact hypersensitivity induction after ultraviolet B radiation via TNF‐receptor 2 (p75) (1999) (7)
Effect of cyclosporine on anterior chamber-associated immune deviation with retinal transplantation. (1997) (7)
Immunogenetic basis of acquired transplantation tolerance. (1984) (7)
EFFECTS OF SUTURE-INDUCED NEOVASCULARIZATION OF THE CORNEA ON THE OCULAR IMMUNOSUPPRESSIVE MICROENVIRONMENT (1994) (6)
Relative roles of T cells and macrophages in cytokine-mediated functional transformation of cultured splenic dendritic cells. (1995) (6)
AN ANALYSIS OF GRAFT-VERSUS-HOST DISEASE IN SYRIAN HAMSTERS: III. HEMATOLOGICAL MANIFESTATIONS: DESCRIPTION AND STUDIES IN PATHOGENESIS (1972) (6)
Haptens can serve as surrogate transplantation antigens in a manner that demonstrates H-2 restriction of graft rejection (1983) (6)
LYMPHOID ORGAN PRODUCTION OF IMMUNOMODULATORY EICOSANOIDS IN MICE RESISTANT TO NEONATAL TOLERANCE INDUCTION (1994) (6)
Progress in the Determination of Histocompatibility (1966) (6)
AN EVALUATION OF THE IRRADIATED HAMSTER TEST AS A MEANS OF PREDICTING HISTOCOMPATIBILITY IN VARIOUS SPECIES (1968) (6)
A mathematical model in immunoregulation where the spleen has a pivotal role. (1976) (6)
Analysis of neonatally induced tolerance of H-2 alloantigens (1983) (6)
Immune response to acute virus infection in the Syrian hamster (2005) (6)
Analysis of neonatally induced tolerance of H-2 alloantigens (2004) (6)
Involvement of cells of hematopoietic origin in genetically determined resistance of Syrian hamsters to vesicular stomatitis virus (1981) (6)
LYMPHOKINE PRODUCTION BY MLR‐REACTIVE REACTION LYMPHOCYTES OBTAINED FROM NORMAL MICE AND MICE RENDERED TOLERANT OF CLASS II MHC ANTIGENS (1989) (6)
STUDIES ON IMMUNE LYMPHOCYTE TRANSFER REACTIONS IN MURINE HOMOLOGOUS CELL CHIMERAS (1970) (6)
Spleen cells from animals neonatally tolerant to H-2Kk antigens recognize trinitrophenyl-modified H-2Kk spleen cells (1977) (6)
Distinct roles for transforming growth factor-beta2 and tumour necrosis factor-alpha in immune deviation elicited by hapten-derivatized antigen-presenting cells. (1999) (6)
Immunochemical characterization of Syrian hamster major histocompatibility complex homologues. (1981) (6)
Cell surface immunoglobulin of hamster lymphoid cells. (1979) (5)
Deviant immune responses to allogeneic tumor cells placed into the anterior chamber protect the intraocular neoplasm, but prevent metastases. (1983) (5)
Allo-I-J determinants participate in maintenance of neonatal H-2 tolerance. (1987) (5)
Studies on transplantation antigen extracts in Syrian hamsters. (1972) (5)
Role of anterior-chamber-associated immune deviation in the pathogenesis of uveitis. (1992) (5)
Analysis of immunologic privilege within the anterior chamber of the eye. (1977) (5)
DISSEMINATED SYSTEMIC EXPRESSION OF THE “LOCAL” POPLITEAL LYMPH NODE ASSAY IN RATS (1976) (5)
Studies on the minimum requirements for in vitro "cure" of tumor cells by cytotoxic T lymphocytes. (1992) (5)
What Do T Lymphocytes “See” When Penetrating Keratoplasty Fails? (2000) (5)
Epidermal Langerhans cells from mice bearing a granulocyte macrophage-colony stimulating factor-producing mammary tumor display impaired accessory functions. (1996) (5)
Alloimmune reactions among recently wild syrian hamsters and classical inbred strains include alloantibody production (1979) (5)
Impaired induction of delayed hypersensitivity following anterior chamber inoculation of alloantigens. (1988) (5)
Transepidermal induction of contact hypersensitivity in mice with a water-soluble hapten. (1993) (4)
Local Immunosuppression: The Eye (2001) (4)
Immunologic privilege evoked by histoincompatible intracameral retinal transplants. (1990) (4)
Abrogation of anterior-chamber-induced suppression of delayed-type hypersensitivity responses by monoclonal anti-I-J antibodies. (1984) (4)
Clonal analysis of helper and effector T-Cell function in neonatal transplantation tolerance: Clonal deletion of helper cells determines lack of in vitro responsiveness (2004) (4)
I-E molecules and I-E-reactive T cells play a central role in neonatal H-2 tolerance. (1991) (4)
Detection of two distinct class II α:β:Ii complexes in the syrian hamster (2004) (4)
Induction of Anterior Chamber-Associated Immune Deviation Requires an Intact, Functional Spleen (2007) (4)
Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation. 1978. (2007) (4)
Immune response and the eye (1999) (4)
Neonatal transplantation tolerance results from two types of suppression acting during induction and at the effector phase. (1981) (4)
MHC class II tolerant T cells undergo apoptosis upon re-exposure to tolerogen in vivo. (1996) (4)
NEURAL RETINA AND RETINAL PIGMENT EPITHELIUM ALLOGRAFTS SUFFER DIFFERENT IMMUNOLOGICAL FATES IN THE EYE (1994) (4)
Ocular molecules and cells that regulate immune responses in situ (1990) (4)
Two antigen presentation pathways, only one of which requires langerhans cells, lead to induction of contact hypersensitivity. Abstr. (1983) (3)
An analysis of epidermolysis in hamsters suffering from homologous disease. (1971) (3)
Corneal Endothelium Confers Immune Privilege on the Cornea as an Allograft (2000) (3)
Definition of the major histocompatibility complex equivalent in Syrian hamsters. (1978) (3)
Evidence for Antigen-Specific Immune Deviation in Patients With Acute Retinal Necrosis (2007) (3)
Antigen-presenting cells and the eye (2007) (3)
Corneal Hemangiogenesis And Lymphangiogenesis Immediately Following Penetrating Keratoplasty Are Triggered By Surgery Rather Than Alloimmunity (2004) (3)
IgE-dependent release of inflammatory mediators from hamster mast cells in vitro. (1981) (3)
Ontogeny of tolerogen-responsive lymphocytes following neonatal inoculation of class II disparate semiallogeneic cells. (1993) (3)
Iris Pigment Epithelial Cells Convert T Cells into CTLA-4 , B 7-Expressing CD 8 Regulatory T Cells (2006) (3)
ANALYSIS OF NEONATALLY INDUCED TOLERANCE OF H‐2 ALLOANTIGENS: IV. Graft Adaptation in Long‐Term Tolerated Grafts (1983) (3)
Two waves of virus following anterior chamber inoculation of HSV-1. 1987. (2007) (3)
Influence of microenvironmental factors on human Langerhans cell function in vitro. (1990) (3)
Advances in gene technology : molecular biology of the immune system : proceedings of the Seventeenth Miami Winter Symposium, Miami, Florida, U.S.A., February 11-15, 1985 (1985) (3)
The Major Histocompatibility System of Cattle, Pig, Rabbit, and Syrian Hamster (1977) (3)
STUDIES ON ANTILYMPHOCYTE SERUM AND TRANSPLANTATION IMMUNITY IN SYRIAN HAMSTERS (1971) (3)
General principles of immuno-ophthalmology. (1999) (3)
New Insights into Prevention of Donor-specific Corneal Graft Rejection (2000) (3)
Partial identification of a delayed reaction effector substance from homologous lymphoid cell mixtures. (1969) (3)
Irradiated hamster test for histocompatibility (1965) (3)
Immunologic reactivity to weak transplantation antigens: factors which favor sensitization rather than tolerance. (1973) (3)
Biochemical characterization of Syrian hamster cell surface alloantigens. III. Hamster alloantisera immunoprecipitate class II-like, but not class I-like, molecules. (1981) (3)
Challenges: On the pathogenesis of immune incompetence in the acquired immune deficiency syndrome (1986) (2)
Hamster T cells participate in MHC alloimmune reactions but do not effect virus-induced cytotoxic activity (1980) (2)
LYMPHOID CELL INTERACTIONS IN ALLOGRAFT IMMUNITY: FAILURE OF HAMSTERS TO GENERATE SUPPRESSOR CELLS UPON SPECIFIC IMMUNIZATION (1978) (2)
Anti-V beta TcR monoclonal antibodies identify and can activate anergic T cells from mice rendered neonatally tolerant of class II alloantigens. (1993) (2)
Characterization of a Syrian hamster plasma cell tumor. (1979) (2)
Immunogenetic susceptibility to uv b as a risk factor for skin cancer in man (1990) (2)
Allogeneic reactions, "adjuvant effect" and response to weak transplantation antigens in hamsters. (1978) (2)
Suprathreshold doses of hapten are required to induce both contact hypersensitivity and tolerance. (2000) (2)
The Effect of IL‐12 on Immune Privilege of the Eye (1996) (2)
Polymorphism at the tumor necrosis factor-alpha locus and susceptibility to toxoplasmic encephalitis, ultraviolet B-induced immune impairment, and mouse AIDS. (1994) (2)
Neonatal tolerance induction acrossH-2 mutational disparity: Induction and specificity of tolerance (2005) (2)
Suppression in class II MHC tolerance is mediated by Ia-specific lymphocytes that fail to mature into allodestructive effectors. (1989) (2)
DIFFERENTIAL EXPRESSION OF HELPER VERSUS EFFECTOR ACTIVITY IN MICE RENDERED NEONATALLY TOLERANT OF CLASS II MHC ANTIGENS (1989) (2)
Syrian hamsters express polymorphism at an MHC equivalent. (1981) (2)
C-type particles in thymic development: a correlation with thymic function. (1981) (2)
Alterations in peripheral V beta 11+ T-cell populations are not predictive of allograft rejection in I-E- mice resistant to neonatal tolerance induction. (1993) (2)
Photoimmunology of non-melanoma skin cancer. (1996) (2)
Inflammatory bowel disease: T lymphocytes may be the culprits. (1978) (1)
T CELLS DO NOT MEDIATE CLONAL DELETION IN TRANSPLANTATION TOLERANCE (1982) (1)
The nature of T cell repertoire modification in neonatal tolerance. (1987) (1)
Reply to DR. Wrench (1981) (1)
Immune privilege and immunogenicity reside among different layers of the mouse cornea. 2000. (2007) (1)
Immunotherapy for cancer. (1978) (1)
Immune modulation by ultraviolet light. (1992) (1)
Immune Modulation by Ultraviolet Light1 (1992) (1)
INDUCTION OF ANTERIOR CHAMBER-ASSOCIATED IMMUNE DEVIATION IN PRE-SENSITIZED MICE (1994) (1)
161 Iris Pigment Epithelium Expressing CD86 (B7-2) Directly Suppresses T Cell Activation In Vitro via Binding to Cytotoxic T Lymphocyte–associated Antigen (2003) (1)
Unusual cell surface immunoglobulin on a plasma cell tumor. (1979) (1)
Hamster immune responses: experimental models linking immunogenetics, oncogenesis and viral immunity: introduction. (1978) (1)
An in vivo and in vitro analysis of the alloantigen response in Syrian hamsters. (1977) (1)
By Altering TNFR2:TNFR1 Expression, TGFb Prevents ACAID-inducing Antigen Presenting Cells from Secreting IL-12 (2003) (1)
Inhibition of Angiogenesis and Lymphangiogenesis After High–Risk Keratoplasty by Neutralizing VEGF–A Improves Corneal Graft Survival (2005) (1)
The hamster major histocompatibility complex and alternate mechanisms of cell-mediated anti-viral cytotoxic activity in the Syrian hamster. (1981) (1)
Expression of CIITA reconstitutes class II MHC expression on corneal endothelial cells: Implications for antigen presentation. (2001) (1)
The Normal Lymphocyte Transfer Reaction (1969) (1)
On the vulnerability of retinal pigment epithelial cells to immune destruction by T cells in vivo (2000) (1)
The Fifth International Congress of the Transplantation Society. (1975) (1)
Cytotoxic t lymphocytes infiltrate into the eye during hsv 1 retinitis (1988) (1)
The paradox of the bone-marrow graft in the immunologically deficient host. (1971) (1)
B7+ Iris Pigment Epithelial Cells Convert Naïve T Cells into CTLA–4+, B7–Expressing CD8+ Regulators (2004) (1)
Induction and regulation of contact hypersensitivity in Syrian hamsters. (1981) (1)
ANTIGENS ON H-2 ALLOGENEIC CELLS* (1979) (0)
THE OCULAR IMMUNOSUPPRESSIVE MICROENVIRONMENT (1994) (0)
On the Cause of Opacity in Rejecting Guinea Pig Corneal Xenografts in Mice (2003) (0)
Activated Macrophages Contribute to Cornea Graft Failure by Targeting Corneal Endothelial Cells (2005) (0)
Responses of langerhans cells to high and low doses of haptens in vivo and in vitro (1998) (0)
A Potential Role For Thombospondin In Corneal Endothelial Cell Injury (2002) (0)
Tolerance to bovine gamma-globulin in adult guinea pigs. (1966) (0)
NOVEL EXPRESSION AND CHARACTERIZATION OF LYMPHATIC VESSEL ENDOTHELIAL HYALURONATE RECEPTOR (LYVE–1) BY OCULAR SURFACE CELLS. (2004) (0)
Qa-1, a Potent Inhibitor of NK and Cytotoxic T Cells, Is Highly Expressed on Cells That Surround the Immune Privileged Anterior Chamber (2003) (0)
Susceptibility of Allo-Ia Specific T Lymphocytes to Unresponsiveness in Neonatal Tolerance (1983) (0)
Macrophage depletion and Delayed Type Hypersensitivity response to alloantigens on orthotopic corneal grafts (2000) (0)
IL-3 production as an in vitro marker of the genetically determined traits of UVB susceptibility and UVB resistance. (1992) (0)
Deviant regulation of class II MHC in corneal endothelial cells. (1999) (0)
Iris Pigment Epithelium (IPE) and IPE Regulatory T Cells Suppress Activation of T Cells via Membrane–Bound TGF–Beta (2006) (0)
Ultraviolet B light impairs contact hypersensitivity and induces tolerance by different immune mechanisms (1993) (0)
SEQUENTIAL TNFa AND GLUTATHIONE PEROXIDASE ACTIVATION IN ACAID–INDUCING, TGFb–TREATED APCS PREVENTS IL–12 PRODUCTION (2004) (0)
Role of IJ Region Determinants in Neonatal Tolerance Induction to K and D Region Alloantigens (1978) (0)
Genetically determined resistance to lethal vesicular stomatitis virus in syrian hamsters. (1981) (0)
Differential patterns of T cell clonal deletion in neonatal H-2 tolerance and I-E/Mls induced self-tolerance. (1994) (0)
Local macrophage depletion improves survival of corneal xenografts in mice by blocking antigen presentation and inhibiting hem– and lymphangiogenesis. (2004) (0)
Detection of two distinct class II alpha:beta:Ii complexes in the Syrian hamster. (1982) (0)
TRUNCATED MATURATION OF ALLOREACTIVE T CELLS IN NEONATALLY H‐2 TOLERANT MICE (1982) (0)
Iris Pigment Epithelium Suppresses T Cell Activation Through a Cell Contact-Dependent Mechanism that Uses B7.2 and CTLA-4 (2003) (0)
Hamsters, unlike rats, fail to regulate responses of immunocompetent cells to alloantigens. (1977) (0)
Deviant regulation of class II MHC expression in corneal endothelial cells (1999) (0)
In CD4+ T Cell Deficient Mice, Th1-like CD8+ T Cells Effect Delayed Rejection of Orthotopic Guinea Pig Cornea Xenografts Via IFN- Rather Than Cytotoxicity (2002) (0)
Increased expression of murine beta cell MHC class I antigens correlates with increased susceptibility to lysis by allogeneic cytotoxic T cells (1990) (0)
Immunosuppression by UVB radiation (1994) (0)
Speculations on the immunopathogenesis of psoriasis: T-cell violation of a keratinocyte sphere of influence. (1990) (0)
Evidence that susceptibility to ultraviolet-B initiated skin diseases in man may be genetically determined (1993) (0)
Protection ofMicefromHerpesSimplex Virus-Induced Retinitis byInVitro-Activated ImmuneCells (1989) (0)
Alterations in Cytokine Production Following Intraocular Injection of Soluble Protein Antigen: Impairment in IFN-γ and Induction of TGF-β and IL-4 Production (1998) (0)
Early Loss of Immune Privilege and Appearance of Immunogenic Inflammation Characterize Eyes of DBA/2J Mice with Pigmentary Glaucoma (2003) (0)
Immunity Deleterious Effects of Ultraviolet B Light on Cutaneous Polymorphism Correlates with α Tumor Necrosis Factor Updated (2006) (0)
Role of VEGFR-3 on Corneal Lymphatic Drainage, Antigen-Presenting Cell Trafficking and Alloimmunity (2003) (0)
De novo Post-transplant Autoimmunty to Retinal Antigens and its Role in Retinal Graft Accommodation (2002) (0)
Ocular Trauma Induced a Secondary Immunosuppressive Microenvironment Containing Active TGF–beta (2005) (0)
Tolerance of class II, but not class I, H-2 alloantigens can be impressed on peripheral immunocompetent lymphocytes by an active process (1983) (0)
Role of Fas Ligand in the Activation of Macrophages by Corneal Endothelial Cells (2003) (0)
TGFß Treatment of ACAID-Inducing Antigen Presenting Cells Prevents IL-12 Secretion by Increasing Nuclear Expression of the NFB Inhibitor IB (2003) (0)
Ontogeny of tolerogen-responsive lymphocytes following neonatal inoculation of class II disparate semiallogeneic cells. (1993) (0)
Regulator T Cells Generated In Vitro by TGFß-Treated Antigen Presenting Cells Endow Fresh Antigen Presenting Cells with ACAID-Inducing Capabilities (2002) (0)
Effects of occlusive dressings on the repopulation of langerhans cells in partial thickness wounds (1991) (0)
Role of Recipient Epithelium in Inhibition of Langerhans Cells Migration into Orthotopic Corneal Allografts (2002) (0)
Concomitant suppression of delayed-type hypersensitivity and stimulation of cytotoxic T-lymphocyte responses to anterior chamber allografts (1984) (0)
Ontogeny of cytotoxic T-cell repertoire modification. (1989) (0)
Minor H-Antigens Presented on Tolerated Haplotype Induce T-Effector Cells Restricted to Tolerated Haplotype. Strong alloreactivity to an unrelated H-2 haplotype in normal animals precludes identifying reactivity to minor H-antigens in an H-2-allogeneic (2003) (0)
Evidence That Mucosal Tolerance, Induced By Allogeneic Cornea Grafts, May Contribute To Graft Acceptance (2002) (0)
Dermal Cells: Underappreciated Components of Skin-Associated Lymphoid Tissues (Salt) (2019) (0)
Comparison of induction of contact hypersensitivity in hamsters and mice. Abstr. (1981) (0)
Tolerance to Bovine γ-Globulin in Adult Guinea Pigs (1966) (0)
Can hamsters suppress allogeneic responsiveness? (1978) (0)
Bright Light, By Recruiting Microglia To The Subretinal Space, Prejudices Survival Of Neonatal Neuronal Retina Allografts (2002) (0)
Ability of neonatally induced tolerance of Ia antigens to overcome adoptive transfer of allo-Ia immunity and to erase its memory. (1984) (0)
RPE Cells Use PEDF And MIF to Confer Innate Immune Privilege On The Subretinal Space (2004) (0)
Iv. the Re]~ractory State and Immunologic Competence (1971) (0)
ARE ALLOGENEIC AND ASSOCIATIVE RECOGNITION COINCIDENT T CELL PARADIGMS? (1981) (0)
Increased Expression of an Inhibitor of NFkappaB, IkappaBalpha, in APCS Endows Them With the ACAID–Inducing Property (2005) (0)
Symposium report. Hamster immune responsiveness and experimental models of infectious and oncologic diseases. (1981) (0)
Tissue Transplantation: Give and Take: The Development of Tissue Transplantation . Francis D. Moore. Saunders, Philadelphia, 1964. xii + 182 pp. Illus. $5.50. (1965) (0)
The Irradiated Hamster Test (2020) (0)
Skin-derived IL-10 following acute, low dose ultraviolet-B radiation creates a systemic antigen presentation defect (1998) (0)
Splenic influence on cellular interactions in allo graft immunity (1975) (0)
Studies on transplantation antigen extracts in Syrian hamsters (1972) (0)
Pro-Inflammatory Effect of Amniotic Epithelial Allografts on Orthotopic Corneal Allografts (2002) (0)
T Cell Suppression by Thrombospondin–1 on Pigment Epithelium (PE) and PE–Dependent Regulatory T Cells in the Eye (2006) (0)
Blood-Brain Barrier That Does Not Depend on the Integrity of the Systemic Immune Deviation in the Brain (2000) (0)
Can a Mammalian Species with Monomorphic Class I MHC Molecules Succeed? (2019) (0)
Approaches to the Study of T-Lymphocytes in Transplantation Tolerance (1993) (0)
Stressed corneal endothelium expresses class II MHC through a CHTA-independent pathway. (2000) (0)
Major histocompatibility complex in syrian hamsters: are SD determinants present? (1977) (0)
The outflow tract serves as the conduit for delivery of antigenic signals important in ocular immune privilege (1992) (0)
Progress in the determination of histocompatibility. 1965. (1999) (0)
Tumor Necrosis Factor a Polymorphism Correlates with Deleterious Effects of Ultraviolet B Light on Cutaneous Immunity1 (2006) (0)
T CELL RECOGNITION OF ANTIGEN IN THE CONTEXT OF H-2 ALLOGENEIC DETERMINANTS OR ANTIGEN H-2 ALLOSPECIFIC RECOGNITION (1980) (0)
Induces t suppressor cells to contact sensitizers. Abstr. (1982) (0)
CD8+ Regulatory T Cells of ACAID Express Genes that Inhibit their Effector Functions, while Promoting their Regulatory Functions (2003) (0)
Inflammation Induced Lymphangiogenesis in the Cornea Arises From Innate Immune Cells (2005) (0)
in ' ' High Risk ' ' Eyes Accept Orthotopic Corneal Allografts Placed Mice with Th 2-Biased Immune Systems (1999) (0)
The MICA5.1 allele is not associated with susceptibility to effects of ultraviolet-B radiation on induction of contact hypersensitivity. (2004) (0)
Cell – Mediated Delayed Rejection of Orthotopic Guinea Pig Cornea Grafts in Mice Deficient in CD 4 T Cells (2002) (0)
Anterior chamber associated immune deviation requires a functional spleen. Abstr. (1981) (0)
Antigen-presenting cells and molecular mechanisms underlying induction of immune deviation (2007) (0)
Mutations in Gpnmb and Tryp1 are required for development of spontaneous anterior uveitis in DBA/2J mice with pigmentary glaucoma (2004) (0)
Anterior chamber associated immune deviation can be induced in mice by herpes simplex virus. Abstr. (1982) (0)
RPE Cells Secrete Soluble Factors Ex Vivo That Inhibit Neutrophil Activation and Prevent NK Cell-Mediated Cytotoxicity (2003) (0)
Homograft reactions in irradiated hamsters (1965) (0)
Pulmonary Pathology Th 2-DependentChamber of the Eye to Inhibit Using Tolerance Induced Via the Anterior (2002) (0)
Nucleotide sequence of the tumor necrosis factor: a gene in seven different inbred mouse strains (2004) (0)
Evidence that Regulator T cells of Eye–Derived Tolerance Can Arise from CD25–Negative Precursors (2004) (0)
In-vitro development of a primary antibody response with dissociated lymph node or spleen cells. Abstr. (1978) (0)
SD determinants and failure of cellular collaboration in hamsters. (1977) (0)
GRAFT‐VERSUS-HOST REACTIONS WITHIN THE THYROID GLAND MAY EVOKE PARI PASSU AUTOIMMUNE THYROIDITIS (1978) (0)
Anterior chember-associated immune deviation: clonal deletion or active suppression? abstr. (1981) (0)
Effects of gamma irradiation on sensitivity of antigen presenting cells (APC) to transforming growth factor beta (TGF-B) (1991) (0)
Immunotherapy of cancer: premises, promises...promises (1976) (0)
Immuno-aspects of the spleen: Proceedings of a Conference on Immunodynamics, Cleveland, Ohio, May 19 and 20, 1976 (1976) (0)
Molecular aspects of herpes simplex virus type 1 induced retinitis (1984) (0)
Thrombospondin (TSP) Is the Primary Molecular Mediator of ACAID-Inducing Properties of TGFß2-Treated Antigen Presenting Cells (APC) (2002) (0)
Haptoglobin is a natural homeostatic factor that prevents epidermal Langerhans cells from activating naive, syngeneic T cells in situ (1998) (0)
PROGRESS IN THE DETERMINATION OF HISTO-COMPATIBILITY. (1965) (0)
Participation of Innate Immune Macrophages in the Pathogenesis of Pigmentary Glaucoma in Mice (2002) (0)
The Immune System in Cutaneous Disease: the Search for a Mouse Model of the Immunopathology of Psoriasis (2020) (0)
On the pathogenesis of immune incompetence in the acquired immune deficiency syndrome. (1986) (0)
Enhancement of survival of intraocular neural retinal grafts by prior antigen-specific immune deviation. (1992) (0)
Anterior chamber injection of S antigen prevents the development of experimental autoimmune uveitis (EAU) (1990) (0)
An analysis of graft-versus-host disease in Syrian hamsters. III. Hematological manifestations: description and studies in pathogenesis. 1972. (2007) (0)
EXPRESSION OF THE COSTIMULATORY B7-1 MOLECULE PREVENTS IMMUNE PRIVILEGE INTHE ANTERIOR CHAMBER OF THE EYE (1994) (0)
AMONG CYTOKINES AND NEUROPEPTIDES IN AQUEOUS HUMOR, ONLY TGF-BETA CONFERSACAID-INDUCING PROPERTIES ON ANTIGEN PRESENTING CELLS IN PHYSIOLOGICAL CONC ENTRATIONS (1994) (0)
Recovery of activated cytotoxic T cells from minor H incompatible tumor graft rejection sites. 1989. (2007) (0)

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Osaka University