Jacek J. Hawiger
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Philosophy
Jacek J. Hawiger's Degrees
- Doctorate Medicine University of Warsaw
- PhD Biochemistry University of Warsaw
Why Is Jacek J. Hawiger Influential?
(Suggest an Edit or Addition)Jacek J. Hawiger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence (*) (1995) (1001)
- Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man. (1983) (671)
- Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the gamma chain. (1984) (465)
- Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis (2005) (288)
- Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate. (1989) (266)
- Measurement of fibrinogen and fibrin degradation products in serum by staphylococcal clumping test. (1970) (260)
- Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells. (1993) (245)
- Innate immunity and inflammation: A transcriptional paradigm (2001) (234)
- Factor IX is activated in vivo by the tissue factor mechanism. (1990) (215)
- Regulation of NF-κB, AP-1, NFAT, and STAT1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NF-κB p50 (1998) (187)
- Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets (1980) (176)
- Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets. (1982) (166)
- The Tax Oncoprotein of Human T-cell Leukemia Virus Type 1 Associates with and Persistently Activates IκB Kinases Containing IKKα and IKKβ* (1998) (148)
- Noninvasive intracellular delivery of functional peptides and proteins. (1999) (142)
- Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells. (1993) (140)
- Identification of a region of human fibrinogen interacting with staphylococcal clumping factor. (1982) (137)
- Formation and regulation of platelet and fibrin hemostatic plug. (1987) (134)
- DETECTION OF FACTOR X ACTIVATION IN HUMANS (1989) (134)
- Localization of a site interacting with human platelet receptor on carboxy-terminal segment of human fibrinogen gamma chain. (1982) (133)
- gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors. (1982) (133)
- Separation of human platelets from plasma proteins including factor VIII VWF by a combined albumin gradient-gel filtration method using HEPES buffer. (1978) (131)
- Interactive Sites in the MyD88 Toll/Interleukin (IL) 1 Receptor Domain Responsible for Coupling to the IL1β Signaling Pathway* (2005) (114)
- Nuclear Import of Proinflammatory Transcription Factors Is Required for Massive Liver Apoptosis Induced by Bacterial Lipopolysaccharide* (2004) (111)
- Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs. (1996) (107)
- Recognition site for the platelet receptor is present on the 15-residue carboxy-terminal fragment of the gamma chain of human fibrinogen and is not involved in the fibrin polymerization reaction. (1983) (104)
- Function of the Classical and Alternate Pathways of Human Complement in Serum Treated with Ethylene Glycol Tetraacetic Acid and MgCl2-Ethylene Glycol Tetraacetic Acid (1975) (100)
- Adenosine diphosphate induces binding of von Willebrand factor to human platelets (1982) (98)
- Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50. (1998) (98)
- Platelet receptor recognition domain on the gamma chain of human fibrinogen and its synthetic peptide analogues. (1989) (97)
- Platelet receptor recognition domains on the alpha chain of human fibrinogen: structure-function analysis. (1989) (97)
- Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules. (1998) (92)
- New paradigms in sepsis: from prevention to protection of failing microcirculation (2015) (88)
- Antibody-detectable changes in fibrinogen adsorption affecting platelet activation on polymer surfaces. (1991) (83)
- PLATELET AGGREGATES IN PERIPHERAL AND CORONARY-SINUS BLOOD IN PATIENTS WITH SPONTANEOUS CORONARY-ARTERY SPASM (1980) (83)
- Proteolytic Processing of NF-B/IB in Human Monocytes (1995) (81)
- Role of the Nuclear Localization Sequence in Fibroblast Growth Factor-1-stimulated Mitogenic Pathways (*) (1996) (80)
- ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets. (1984) (78)
- Staphylococci-induced human platelet injury mediated by protein A and immunoglobulin G Fc fragment receptor. (1979) (75)
- Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18 (2016) (73)
- Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny. (2006) (69)
- Peptide-directed Suppression of a Pro-inflammatory Cytokine Response* (2000) (66)
- Evidence that changes in platelet cyclic AMP levels regulate the fibrinogen receptor on human platelets. (1982) (65)
- STAPHYLOCOCCAL CLUMPING WITH SOLUBLE FIBRIN MONOMER COMPLEXES (1967) (62)
- Mechanisms Involved in Platelet Vessel Wall Interaction (1995) (60)
- Platelet Aggregates in Ischemic Heart Disease (1980) (56)
- Isolation of human platelets by albumin gradient and gel filtration. (1989) (55)
- Membrane Changes in Human Platelets Induced by Lipopolysaccharide Endotoxin (1977) (55)
- Affinity isolation and characterization of immunoglobulin G Fc fragment-binding glycoprotein from human blood platelets. (1979) (53)
- Isolation, characterization, and synthesis of peptides from human fibrinogen that block the staphylococcal clumping reaction and construction of a synthetic clumping particle. (1982) (53)
- Receptor/Transporter-independent Targeting of Functional Peptides across the Plasma Membrane* (2004) (52)
- The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta. (1998) (51)
- Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor. (2009) (49)
- Three-dimensional structure of the platelet integrin recognition segment of the fibrinogen gamma chain obtained by carrier protein-driven crystallization. (1994) (47)
- Suppression of Staphylococcal Enterotoxin B-induced Toxicity by a Nuclear Import Inhibitor* (2004) (46)
- IκB Kinase Complex Is an Intracellular Target for Endotoxic Lipopolysaccharide in Human Monocytic Cells (1999) (46)
- Cellular import of functional peptides to block intracellular signaling. (1997) (46)
- Precipitation of Soluble Fibrin Monomer Complexes by Lysosomal Protein Fraction of Polymorphonuclear Leukocytes∗ (1969) (45)
- A beta-turn is present in the 392-411 segment of the human fibrinogen gamma-chain. Effects of structural changes in this segment on affinity to antibody 4A5. (1992) (45)
- Immunoassay of human platelet factor 4(PF4, antiheparin factor) by radial immunodiffusion. (1976) (42)
- Fractalkine and CX3CR1 Mediate Leukocyte Capture by Endothelium in Response to Shiga Toxin1 (2008) (42)
- Endotoxin-sensitive membrane component of human platelets (1975) (40)
- Structure of the fibrinogen γ‐chain integrin binding and factor XIIIa cross‐linking sites obtained through carrier protein driven crystallization (1999) (40)
- INTERACTION OF FIBRINOGEN WITH STAPHYLOCOCCAL CLUMPING FACTOR AND WITH PLATELETS * (1983) (39)
- The integrin alpha v gene: identification and characterization of the promoter region. (1994) (39)
- Complex formation of platelet membrane glycoproteins IIb and IIIa with the fibrinogen D domain. (1984) (39)
- Interaction of human fibrinogen with staphylococci: presence of a binding region on normal and abnormal fibrinogen variants and fibrinogen derivatives. (1978) (33)
- Platelet aggregation by fibrinogen polymers crosslinked across the E domain. (1986) (33)
- Decoding inflammation, its causes, genomic responses, and emerging countermeasures (2019) (32)
- Mechanism of human platelet activation by endotoxic glycolipid-bearing mutant Re595 of Salmonella minnesota. (1986) (32)
- Adhesive ends of fibrinogen and its antiadhesive peptides: the end of a saga? (1995) (32)
- Targeting Nuclear Import Shuttles, Importins/Karyopherins alpha by a Peptide Mimicking the NFκB1/p50 Nuclear Localization Sequence (2013) (32)
- Interaction of platelets with the vessel wall (1985) (32)
- Structural characterization of monophosphoryl lipid A homologs obtained from Salmonella minnesota Re595 lipopolysaccharide. (1990) (31)
- Modulation of human platelet protein kinase C by endotoxic lipid A. (1988) (31)
- y and a chains of human fibrinogen possess sites reactive with human platelet receptors (29)
- Adhesive Interactions of Platelets and Their Blockade a (1991) (28)
- Antiplatelet "hybrid" peptides analogous to receptor recognition domains on gamma and alpha chains of human fibrinogen. (1989) (27)
- Platelet secretory pathways: an overview. (1989) (26)
- Reactivity of synthetic peptide analogs of adhesive proteins in regard to the interaction of human endothelial cells with extracellular matrix. (1991) (26)
- Fibrinogen-mediated epidermal cell migration: structural correlates for fibrinogen function. (1989) (26)
- Interaction of Histoplasma capsulatum with human platelets. (1980) (25)
- Extended Anti-inflammatory Action of a Degradation-resistant Mutant of Cell-penetrating Suppressor of Cytokine Signaling 3* (2010) (25)
- Purification and Properties of Lysozyme Produced by Staphylococcus aureus (1968) (25)
- The effects of RO-22-4679, a thromboxane synthetase inhibitor, on ventricular fibrillation induced by coronary artery occlusion in conscious dogs. (1983) (24)
- Nuclear Transport Modulation Reduces Hypercholesterolemia, Atherosclerosis, and Fatty Liver (2013) (22)
- Intracellular Delivery of a Cell-Penetrating SOCS1 that Targets IFN-γ Signaling (2009) (22)
- Interleukin 2 Activates Brain Microvascular Endothelial Cells Resulting in Destabilization of Adherens Junctions* (2016) (21)
- IkappaB kinase complex is an intracellular target for endotoxic lipopolysaccharide in human monocytic cells. (1999) (20)
- COMPLEMENT-DEPENDENT PLATELET INJURY BY STAPHYLOCOCCAL PROTEIN A (1972) (20)
- Human fibrinogen possesses binding site for staphylococci on Aα and Bβ polypeptide chains (1975) (20)
- Frequency of staphylococcal lysozyme production tested by plate method (1968) (20)
- In Vivo Islet Protection by a Nuclear Import Inhibitor in a Mouse Model of Type 1 Diabetes (2010) (19)
- The “Genomic Storm” Induced by Bacterial Endotoxin Is Calmed by a Nuclear Transport Modifier That Attenuates Localized and Systemic Inflammation (2014) (18)
- The Innate Immunity Adaptor SARM Translocates to the Nucleus to Stabilize Lamins and Prevent DNA Fragmentation in Response to Pro-Apoptotic Signaling (2013) (17)
- Binding of fibrinogen and von Willebrand factor to platelet glycoprotein IIb-IIIa complex. (1992) (17)
- Electron Microscopy of Fibrin‐like Precipitate Formed during the Paracoagulation Reaction between Soluble Fibrin Monomer Complexes and Protamine Sulphate (1969) (17)
- Interaction of endotoxic lipid A and lipid X with purified human platelet protein kinase C. (1990) (17)
- Cutting Edge: The “Death” Adaptor CRADD/RAIDD Targets BCL10 and Suppresses Agonist-Induced Cytokine Expression in T Lymphocytes (2012) (16)
- How to approach genome wars in sepsis? (2011) (16)
- Interaction of Artificial Phospholipid Membranes with Isolated Polymorphonuclear Leucocytic Granules (1969) (16)
- Heartfelt sepsis: microvascular injury due to genomic storm. (2018) (15)
- Macromolecules That Link Platelets following Vessel Wall Injury a (1987) (15)
- Endotoxic lipid A interaction with human platelets. Structure-function analysis of lipid A homologs obtained from Salmonella minnesota Re595 lipopolysaccharide. (1990) (15)
- Repertoire of platelet receptors. (1992) (15)
- von Willebrand factor can substitute for plasma fibrinogen in ADP-induced platelet aggregation. (1986) (15)
- Proteolytic processing of NF-kappa B/I kappa B in human monocytes. ATP-dependent induction by pro-inflammatory mediators. (1995) (14)
- Platelets : receptors, adhesion, secretion (1989) (13)
- Activation and release of lysosomal enzymes from isolated leukocytic granules by liposomes. A proposed model for degranulation in polymorphonuclear leukocytes. (1969) (10)
- Degradation products of fibrinogen and fibrin in bacteremia due to gram-negative rods. (1973) (10)
- Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles (2017) (10)
- Staphylococcal Clumping and Fibrinogen and Fibrin Degradation Products in Inflammatory Exudate 1 (1971) (10)
- The Adaptor CRADD/RAIDD Controls Activation of Endothelial Cells by Proinflammatory Stimuli* (2014) (10)
- Complement and Coagulation in Rocky Mountain Spotted Fever (1973) (10)
- The resistance to antibiotics of strains of Staphylococcus aureus isolated in Poland. (1966) (9)
- Reactivity of chemically cross-linked fibrinogen and its fragments D toward the staphylococcal clumping receptor. (1987) (9)
- Sensitivity of Staphylococcus aureus to 30 antibiotics. (1969) (8)
- ON THE IMMUNOLOGIC NATURE OF ANTITHROMBIN IN THE COURSE OF LUPUS ERYTHEMATOSUS DISSEMINATUS. (1964) (8)
- Lethality in a Murine Model of Pulmonary Anthrax is Reduced by Combining Nuclear Transport Modifier with Antimicrobial Therapy (2012) (8)
- Antibiotic sensitivity of Micrococcus radiodurans. (1967) (7)
- Platelet Activation by Polyalkyl Acrylates and Methacrylates: The Role of Surface-Bound Fibrinogen (1987) (6)
- Report of the Task Force on Vascular Medicine. (1994) (6)
- Regulation of NFk B , AP-1 , NFAT , and STAT 1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NFk B p 501 (1998) (6)
- Mechanism triggering platelet hemostatic plug formation in vivo. (1984) (6)
- Disseminated intravascular coagulation in patients with infections: diagnostic and therapeutic approach. (1976) (5)
- CRYOCOAGULOPATHY WITH PRESENCE OF IMMUNOANTITHROMBIN IN THE COURSE OF LUPUS ERYTHEMATOSUS DISSEMINATUS. (1964) (5)
- EGF receptor–mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling (2020) (5)
- Activation of lysosomal enzymes in polymorphonuclear leukocytic granules: the role of phospholipid-protein interaction. (1972) (4)
- Dynamic changes in the membrane of leukocyte lysosomes detected with fluorescent probe and accompanied by release of lysosomal enzymes. (1973) (4)
- The resistance to antibiotics of strains of Streptococcus viridans, Streptococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Proteus and Klebsiella isolated in Poland. (1966) (3)
- Lipopolysaccharide-induced signal transduction and gene transcription (1994) (3)
- Purification andProperties ofLysozyme Produced byStaphylococcus aureus (1968) (3)
- The Role of Membrane Receptors in Pathways of Human Platelet Activation by Endotoxin and other Microbial Products (1975) (3)
- Human fibrinogen possesses binding site for staphyococci on Aalpha and Bbeta polypeptide chains. (1975) (2)
- Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles (2021) (2)
- The Receptor For Factor VIII/VWF On Human Platelets: Its Appearance And Disappearance Upon Action Of Thrombin And Prostacyclin (1981) (2)
- Protection from Endotoxin Shock by Selective Targeting of Proinflammatory Signaling to the Nucleus Mediated by Importin Alpha 5 (2019) (2)
- Genomic control of inflammation in experimental atopic dermatitis (2022) (1)
- Symposium on hemostasis: molecular and cellular pathology (1987) (1)
- Introduction to platelet structural and functional organization. (1992) (1)
- Proceedings: Pathobiology of human fibrinogen. Binding site for staphylococci on Aalpha and Bbeta chains of fibrinogen molecule. (1975) (1)
- Frequency ofstaphylococcal lysozyme production tested byplate method (1968) (1)
- REGULATION OF FIBRINOGEN RECEPTOR ON HUMAN PLATELETS BY CHANGES IN PLATELET CYCLIC AMP LEVELS * (1983) (1)
- [Staphylococcal lysozyme. II. Purification of lysozyme produced by Staphylococcus aureus 524]. (1968) (1)
- Antibiotic Sensitivity ofMicrococcus radiodurans (1967) (0)
- Nuclear Localization Sequence of NF-Noninvasive Delivery of Peptide Carrying the STAT 1 Nuclear Import in T Lymphocytes by B , AP-1 , NFAT , and κ Regulation of NF - (1998) (0)
- Immunology at vanderbilt university (2001) (0)
- to the interaction of human endothelial cells with extracellular matrix Reactivity of synthetic peptide analogs of adhesive proteins in regard (2011) (0)
- Cell-permeable peptide to inhibit inflammatory responses and their use (2000) (0)
- The Role Of Fc Fragment Receptor in Immune Injury of Human Platelets Induced by Protein a of Staphylococci (1977) (0)
- PLATELET RECEPTOR RECOGNITION DOMAINS AND THEIR SYNTHETIC PEPTIDE ANALOGS (1987) (0)
- [Synthesis and lysis of the cell wall of staphylococci]. (1968) (0)
- 5. 3D-structure of human fibrinogen gamma chain ???business end??? interacting with platelet integrin GPIIb-IIIa and factor XIIIa (1998) (0)
- Expression in T Lymphocytes Suppresses Agonist-Induced Cytokine CRADD/RAIDD Targets BCL10 and Cutting Edge: The ''Death'' Adaptor (2012) (0)
- Kinase Complex Is an Intracellular Target for Endotoxic Lipopolysaccharide in Human Monocytic Cells (1999) (0)
- derivatives region on normal and abnormal fibrinogen variants and fibrinogen Interaction of human fibrinogen with staphylococci: presence of a binding (2012) (0)
- A stand-off between rhAPC and LPS in healthy human subjects (2003) (0)
- Effect ofVegetarianism andSmoking onVitamin B12, Thiocyanate, andFolate Levels intheBloodofNormal Subjects (1972) (0)
- United States Patent ( 19 ) Stuttle 54 SYNTHETICPEPTIDES FOR USE IN TUMOR DETECTION (2017) (0)
- United States Patent ( 19 ) Charo et al . 54 PEPTIDES DERIVED FROM GPA ( 75 ) Inventors : Israel (2017) (0)
- Adhesive interactions of platelets and their blockade with synthetic peptides (1990) (0)
- mutant Re595 of Salmonella minnesota Mechanism of human platelet activation by endotoxic glycolipid-bearing (2011) (0)
- Platelet receptor recognition domain on the .gamma. chain of human fibrinogen and its synthetic peptide analogs [Erratum to document cited in CA110(17):151810E] (1989) (0)
- Three-dimensional structure of the platelet integrin recognition (2004) (0)
- The inducible nuclear import of NF-κB, AP-1, and NF-AT in stimulated human T-lymphocytes (1996) (0)
- Peptide/Protein Delivery (2002) (0)
- Platelets : Vol. 215, Pt. B: Receptors, Adhesion, Secretion (1992) (0)
- Cellular import of functional peptides (2002) (0)
- Activation ofLysosomal Enzymes inPolymorphonuclear Leukocytic Granules: TheRoleofPhospholipid-Protein Interaction* (1972) (0)
- Structural characterization of the recognition site for platelet receptors on human fibrinogen (1985) (0)
- Aggregation of human platelets by endotoxic glycolipid-bearing Salmonella minnesota Re595 is prevented by synthetic peptide analogs of cell adhesion sites of fibrinogen and fibronectin (1986) (0)
- Separation of Human Blood Platelets from Factor VIII (Von Willebrand’s Factor) by Combined Albumin Gradient-Gel Filtration Method (1977) (0)
- Functional maturation of invariant natural T (iNKT) cells is under the control of GM-CSF (2006) (0)
- Pathobiology of Human Fibrinogen. Binding site for Staphylococci on Aα and Bβ chains of Fibrinogen Molecule (1975) (0)
- Shiga Toxin Capture by Endothelium in Response to Fractalkine and CX3CR1 Mediate Leukocyte (2008) (0)
- Importin Alpha 5 Proinflammatory Signaling to the Nucleus Mediated by Protection from Endotoxin Shock by Selective Targeting of (2019) (0)
- [Antibiotic treatment: errors and suggestions]. (1967) (0)
- ON SOME ASPECTS OF THE ANTIBODIES DEFICIENCY SYNDROME. (1963) (0)
- REGULATION OF PLATELET RECEPTORS FOR FIBRINOGEN AND VON WILLEBRAND FACTOR BY PROTEIN KINASE (1987) (0)
- [Staphylococcal lysozyme. 3. Factors influencing the course of reaction of staphylococcal lysozyme]. (1968) (0)
- The Regulatory Role Of Camp In Induction Of Human Platelet Receptor For Fibrinogen (1981) (0)
- [THE ANTIBODY DEFICIENCY SYNDROME AND MUCOVISCIDOSIS]. (1963) (0)
- A method for preventing the binding of von Willebrand factor to human platelets and to stimulate the interaction of platelets with vessel walls. (1985) (0)
- [Intradepartmental infection in a children's clinic]. (1969) (0)
- Immune Injury to Human Platelets Mediated By IgG Fc Receptor is Prevented by Prostacyclin (1979) (0)
- [THE ANTIBODY DEFICIENCY SYNDROME AND MUCOVISCIDOSIS]. (1963) (0)
- A method for the prevention and induction of human platelet aggregation. (1985) (0)
- Dr. Mario Baldini (January 15, 1917-August 4, 1986). (1987) (0)
- Demonstration of the platelet Fc receptor by using a photosensitive heterobifunctional cross-linking reagent (1986) (0)
- Inhibition of adhesive receptors: Research initiatives in vascular surgery * (1989) (0)
- METHODS AND COMPOSITIONS FOR TREATING MICROBIAL INFLAMMATION (2018) (0)
- [Staphylococcal lysozyme. 4. Lysozyme activity towards various substrates]. (1968) (0)
- [Susceptibility of Staphylococcus aureus to the effect of 30 antibiotics in vitro]. (1969) (0)
- Mobilization of Fibrinogen Receptor Sites on Human Platelets Stimulated with ADP is Prevented by Prostacyclin (1979) (0)
- [Staphylococcal lysozyme. I. Occurrence of lysozyme in comparison with the other staphylococcal factors]. (1967) (0)
- Expression Of The Fc Receptor On Human Platelets Is Regulated By Cyclic Amp Changes (1981) (0)
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