Jack Gauldie
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Canadian pathologist
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Pathology
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Why Is Jack Gauldie Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jack Gauldie, is a Canadian pathologist, having been a Distinguished University Professor at McMaster University.
Jack Gauldie's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The acute phase response. (1994) (2182)
- Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. (1987) (1596)
- IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. (1998) (1500)
- Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. (1997) (1008)
- The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? (2008) (795)
- Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. (2001) (699)
- Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. (2009) (502)
- Late cutaneous allergic responses in isolated IgE-dependent reactions. (1973) (435)
- Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis (2000) (410)
- Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis1 (2004) (374)
- Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis. (2011) (372)
- Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. (2012) (372)
- Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation. (1990) (345)
- Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells. (1987) (332)
- Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes. (1994) (320)
- Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. (2010) (312)
- The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization. (1977) (287)
- Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation. (1994) (283)
- Pulmonary fibrosis: searching for model answers. (2005) (276)
- Acute Phase Proteins (1985) (275)
- Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts. (1998) (273)
- Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung. (2001) (273)
- Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells. (1982) (272)
- Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. (2005) (258)
- Inhibition of Injury Induced Thromboatherosclerotic Lesions by Anti-Platelet Serum in Rabbits (1976) (242)
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. (1996) (237)
- Heterogeneous proliferative characteristics of human adult lung fibroblast lines and clonally derived fibroblasts from control and fibrotic tissue. (1988) (234)
- Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells. (1982) (232)
- Bronchial epithelial cell-derived cytokines (G-CSF and GM-CSF) promote the survival of peripheral blood neutrophils in vitro. (1992) (224)
- Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1). (1992) (217)
- TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis1 (2005) (216)
- Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. (1996) (216)
- Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function. (2001) (213)
- Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells. (1987) (212)
- IL-12 gene therapy protects mice in lethal Klebsiella pneumonia. (1996) (207)
- Endogenous interleukin‐6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice (1999) (203)
- The peptide components of bee venom. (1976) (198)
- VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. (2009) (197)
- Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. (2002) (194)
- Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. (1995) (187)
- Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro. (1992) (186)
- Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin. (2001) (185)
- The acute phase response of the liver in inflammation. (1990) (182)
- Pulmonary hypertension and idiopathic pulmonary fibrosis: a tale of angiogenesis, apoptosis, and growth factors. (2011) (180)
- A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity (2013) (178)
- Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. (2002) (173)
- Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. (2011) (172)
- Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. (2003) (170)
- Hemoglobin ontogeny during normal mouse fetal development. (1979) (169)
- Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. (2011) (168)
- Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils (1997) (168)
- Dissecting fibrosis: therapeutic insights from the small-molecule toolbox (2015) (166)
- Promotion of eosinophil survival by human bronchial epithelial cells and its modulation by steroids. (1991) (163)
- Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. (1997) (161)
- Re-evaluation of fibrogenic cytokines in lung fibrosis. (2003) (159)
- Interleukin 10 gene transfer prevents experimental colitis in rats (2000) (158)
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. (2006) (156)
- Interleukin-6 is a centrally acting endogenous pyrogen in the rat. (1991) (156)
- Steroid inhibition of cytokine-mediated vasodilation after warm heart surgery. (1995) (153)
- Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs. (2004) (151)
- Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. (1998) (150)
- Immune-mediated thrombocytopenia of malaria. (1983) (147)
- Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture. (1993) (146)
- Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination. (1997) (145)
- The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines. (1984) (144)
- Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. (2003) (143)
- TGF-β, Smad3 and the process of progressive fibrosis (2007) (143)
- Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneum. (2002) (140)
- Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3 (2008) (140)
- TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. (2005) (139)
- Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL1 (2007) (138)
- IL-6 functions as an exocrine hormone in inflammation. Hepatocytes undergoing acute phase responses require exogenous IL-6. (1990) (138)
- TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). (1994) (137)
- Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis. (2016) (136)
- Cellular and genetic basis for suppression of cytotoxic T cell generation by haloaromatic hydrocarbons. (1983) (136)
- Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial (1999) (135)
- Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis (2010) (134)
- TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis. (2005) (133)
- Elevated platelet-associated IgG in the thrombocytopenia of septicemia. (1979) (131)
- Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination (1997) (129)
- Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. (1997) (128)
- A new direction in the pathogenesis of idiopathic pulmonary fibrosis? (2001) (127)
- Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: in vitro and in vivo production of biologically active interleukin-12. (1996) (127)
- Antiangiogenic and antifibrotic gene therapy in a chronic infusion model of peritoneal dialysis in rats. (2002) (126)
- Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin (2002) (126)
- Systemic administration of ciliary neurotrophic factor induces cachexia in rodents. (1994) (125)
- The use of adenoviral vectors for gene therapy and gene transfer in vivo. (1995) (124)
- Therapeutic effect of angiostatin gene transfer in a murine model of endometriosis. (2002) (123)
- Cytokines and pulmonary fibrosis. (1993) (123)
- Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation. (1997) (123)
- Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injury in Vivo (2003) (121)
- Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. (2004) (121)
- Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta. (1998) (120)
- Smad3 signaling involved in pulmonary fibrosis and emphysema. (2006) (119)
- Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue. (1993) (119)
- TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis1 (2007) (118)
- Effect of histamine on proliferation of normal human adult lung fibroblasts. (1988) (115)
- Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β (2003) (114)
- Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models. (1999) (113)
- Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors (1998) (112)
- Enhanced Suppressor Cell Activity as a Mechanism of Immunosuppression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin 1 (1981) (109)
- Transforming growth factor-beta gene transfer to the lung induces myofibroblast presence and pulmonary fibrosis. (1999) (108)
- Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. (2010) (108)
- Reciprocal actions of interleukin‐6 and brain‐derived neurotrophic factor on rat and mouse primary sensory neurons (2000) (107)
- Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis. (1991) (106)
- IFNβ2/BSF2/IL‐6 Is the Monocyte‐derived HSF That Regulates Receptor‐specific Acute Phase Gene Regulation in Hepatocytes a (1989) (106)
- Inflammatory Mechanisms Are Not a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis (2002) (106)
- Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung. (1994) (104)
- Sensitivity to suppression of cytotoxic T cell generation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the Ah genotype of the murine host. (1984) (104)
- TGF-beta, Smad3 and the process of progressive fibrosis. (2007) (104)
- Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection. (2011) (102)
- Human lung fibroblast-derived granulocyte-macrophage colony stimulating factor (GM-CSF) mediates eosinophil survival in vitro. (1989) (102)
- Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM‐CSF in pulmonary inflammation (1996) (99)
- Hormonal regulation and tissue-specific localization of alpha 2-macroglobulin in rat ovarian follicles and corpora lutea. (1989) (96)
- Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation (2013) (96)
- Pulmonary function abnormalities in patients with inflammatory bowel disease. (1982) (95)
- Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. (2008) (95)
- Monocyte-macrophage differentiation induced by human upper airway epithelial cells. (1991) (95)
- ANTI‐INTERLEUKIN-12 THERAPY PROTECTS MICE IN LETHAL ENDOTOXEMIA BUT IMPAIRS BACTERIAL CLEARANCE IN MURINE ESCHERICHIA COLI PERITONEAL SEPSIS (1997) (91)
- Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. (2008) (91)
- Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer (2003) (89)
- Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia (1997) (89)
- Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls. (2006) (88)
- Transgenic expression of granulocyte-macrophage colony-stimulating factor induces the differentiation and activation of a novel dendritic cell population in the lung. (2000) (87)
- Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia (2011) (85)
- IL6 and the acute phase reaction. (1992) (85)
- Lipopolysaccharide induces expression of granulocyte/macrophage colony-stimulating factor, interleukin-8, and interleukin-6 in human nasal, but not lung, fibroblasts: evidence for heterogeneity within the respiratory tract. (1993) (85)
- Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12 (2001) (83)
- Spontaneous in vitro release of alveolar-macrophage cytokines after the intratracheal instillation of bleomycin in rats. Characterization and kinetic studies. (1988) (83)
- TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway. (2002) (83)
- Adenovirus-mediated interleukin-10 gene transfer inhibits post-transplant fibrous airway obliteration in an animal model of bronchiolitis obliterans. (1998) (82)
- Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. (2008) (81)
- Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα (1997) (81)
- Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer (2013) (80)
- Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo. (2008) (80)
- A role for CD4+ T cells in the pathogenesis of skin fibrosis in tight skin mice (1994) (80)
- Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells (2004) (79)
- Epithelial expression of profibrotic mediators in a model of allergen-induced airway remodeling. (2005) (78)
- Synthesis of IgG, IgA, IgM by chicken tissues: immunofluorescent and 14C amino acid incorporation studies. (1973) (77)
- The structures of some peptides from bee venom. (1978) (76)
- Comparison between conventional and "clinical" assessment of experimental lung fibrosis (2008) (76)
- Fibroblast growth factor‐1 attenuates TGF‐β1‐induced lung fibrosis (2016) (75)
- A radioimmunoassay for serum ferritin. (1977) (74)
- Synthesis of antithrombin III and alpha-1-antitrypsin by the perfused rat liver. (1978) (74)
- Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro. (1987) (73)
- Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice. (2005) (73)
- Neutrophilic differentiation induced by human upper airway fibroblast-derived granulocyte/macrophage colony-stimulating factor (GM-CSF). (1991) (72)
- Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice. (2000) (72)
- A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model. (1998) (71)
- Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin (2015) (71)
- Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity (2001) (71)
- Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis (2018) (71)
- Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue. (1994) (70)
- Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA (1998) (70)
- TGF-β receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung (2008) (69)
- Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis. (1999) (69)
- Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo. (1993) (68)
- Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function. (1993) (68)
- Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis. (2011) (68)
- Pseudothrombocytopenia due to platelet aggregation and degranulation in blood collected in EDTA. (2009) (67)
- Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3. (2006) (67)
- Estradiol Promotes Growth and Angiogenesis in Polyoma Middle T Transgenic Mouse Mammary Tumor Explants (2003) (67)
- A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer (2003) (67)
- Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells. (1999) (67)
- Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge. (2006) (66)
- Cytokine control of acute phase protein expression. (1991) (66)
- Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats. (2010) (65)
- The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size. (1979) (64)
- Lung development and susceptibility to chronic obstructive pulmonary disease. (2006) (63)
- Monitoring soluble interleukin-2 receptor levels in related and unrelated donor allogeneic bone marrow transplantation (1998) (63)
- Von Willebrand's syndrome presenting as an acquired bleeding disorder in association with a monoclonal gammopathy. (1973) (62)
- Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. (2003) (62)
- The relationship among platelet-associated IgG, platelet lifespan, and reticuloendothelial cell function (1984) (62)
- Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. (2006) (61)
- Limited effects of recombinant human and murine interleukin 1 and tumour necrosis factor on production of acute phase proteins by cultured rat hepatocytes. (1987) (60)
- Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs. (2011) (60)
- Elafin/elastase-specific inhibitor in bronchoalveolar lavage of normal subjects and farmer's lung. (1996) (58)
- Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters (1998) (58)
- Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes. (1990) (58)
- Fc receptors for IgA and other immunoglobulins on resident and activated alveolar macrophages. (1983) (57)
- Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy1 (2001) (57)
- The acute phase protein response during parasitic infection. (1991) (57)
- Synergy in induction of increased renal allograft survival after portal vein infusion of dendritic cells transduced to express TGFbeta and IL-10, along with administration of CHO cells expressing the regulatory molecule OX-2. (2000) (57)
- The importance of interventional timing in the bleomycin model of pulmonary fibrosis (2020) (57)
- Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1 (2005) (56)
- Enhanced Antitumor Immunity Elicited by Dendritic Cell Vaccines Is a Result of Their Ability to Engage Both CTL and IFNγ-producing NK Cells. (2008) (56)
- Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis (2019) (55)
- Human upper airway structural cell-derived cytokines support human peripheral blood monocyte survival: a potential mechanism for monocyte/macrophage accumulation in the tissue. (1992) (55)
- Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury (1999) (55)
- Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1-type pulmonary granulomas. (1997) (54)
- The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis (2014) (54)
- Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin. (1992) (54)
- IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System1 (2007) (52)
- Recombinant Human Adenovirus with Rat MIP‐2 Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain (1996) (52)
- Structural cell-derived cytokines in allergic inflammation. (1991) (51)
- Extracellular matrix microenvironment contributes actively to pulmonary fibrosis (2013) (51)
- Transient gene transfer of IL-12 regulates chemokine expression and disease severity in experimental arthritis. (1998) (51)
- Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung. (1996) (50)
- Adenoviral-mediated Gene Transfer to Mouse Salivary Glands (2000) (50)
- A single intramuscular injection with an adenovirus-expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatment with an IL-4-expressing vector increases disease susceptibility in B10.D2 mice. (1999) (50)
- Behavioral Effects of Infection with IL-6 Adenovector (2001) (49)
- Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome. (1999) (49)
- Mast cell involvement in various inflammatory processes. (1987) (49)
- Overexpression of transforming growth factor-&bgr;1 in fetal monkey lung results in prenatal pulmonary fibrosis (2010) (49)
- Pro: Inflammatory mechanisms are a minor component of the pathogenesis of idiopathic pulmonary fibrosis. (2002) (49)
- Tumour therapy in mice using adenovirus vectors expressing human TNFa. (1998) (49)
- Chicken immunoglobulin resembling A. (1972) (49)
- Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection1 (2007) (48)
- Proinflammatory properties of IL-4 in the intestinal microenvironment. (2005) (48)
- Bone marrow-derived dendritic cell vaccination of dogs with naturally occurring melanoma by using human gp100 antigen. (2005) (48)
- Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo. (2016) (45)
- Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer. (2014) (45)
- The concentration of IgG in the serum is a major determinant of Fc-dependent reticuloendothelial function. (1985) (45)
- Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer (2000) (45)
- Acute phase response in infectious disease. (1985) (44)
- Cell-specific gene expression in patients with usual interstitial pneumonia. (2006) (44)
- Three-dimensional computed tomography imaging in an animal model of emphysema (2007) (43)
- The Microenvironmental Differentiation Hypothesis of Airway Inflammation (1990) (43)
- Animal models of pulmonary fibrosis: how far from effective reality? (2008) (43)
- Oncostatin M, but not interleukin-6 or leukemia inhibitory factor, stimulates expression of alpha1-proteinase inhibitor in A549 human alveolar epithelial cells. (1997) (42)
- Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines. (2000) (42)
- The acute phase protein response during parasitic infection (1991) (41)
- Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis. (1997) (41)
- Models of pulmonary fibrosis (2006) (40)
- Chicken A: physicochemical and immunochemical characteristics. (1973) (40)
- A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells (2015) (40)
- Gene therapy for pulmonary diseases. (2006) (40)
- Dendritic Cells Derived from Murine Colonic Mucosa Have Unique Functional and Phenotypic Characteristics1 (2007) (40)
- Adenoviral gene transfer of bioactive TGFβ1 to the rodent eye as a novel model for anterior subcapsular cataract (2007) (39)
- Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation. (2004) (39)
- IL-6 stimulates vitronectin gene expression in vivo. (1995) (39)
- Fibroblasts and other structural cells in airway inflammation. (1992) (39)
- Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells. (1996) (39)
- Adenovector engineered interleukin-2 expressing autologous plasma cell vaccination after high-dose chemotherapy for multiple myeloma - a phase 1 study (2001) (39)
- Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression. (1999) (38)
- Human upper airway epithelial cell-derived granulocyte-macrophage colony-stimulating factor induces histamine-containing cell differentiation of human progenitor cells. (1991) (38)
- Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes. (1991) (38)
- Metabolic changes in rats during a continuous infusion of recombinant interleukin-1. (1996) (38)
- Lysyl Oxidase‐Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor‐&bgr;1‐induced Pulmonary Fibrosis (2017) (38)
- Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection (2015) (38)
- Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of lung morphogenesis. (1999) (38)
- Adenoviral vector expressing murine angiostatin inhibits a model of breast cancer metastatic growth in the lungs of mice. (2001) (37)
- TGF-beta effects on epithelial ion transport and barrier: reduced Cl- secretion blocked by a p38 MAPK inhibitor. (2002) (36)
- Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension (2018) (36)
- Fibrocytes and Fibroblasts - where are we now. (2019) (36)
- Immunization with a bivalent adenovirus-vectored tuberculosis vaccine provides markedly improved protection over its monovalent counterpart against pulmonary tuberculosis. (2009) (36)
- Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection (2008) (36)
- Immunohistochemical localization of alpha 1-antitrypsin in normal mouse liver and pancreas. (1980) (36)
- Motilin, human pancreatic polypeptide (HPP) and gastrin plasma concentrations in fasting subjects. (1979) (35)
- Adenovirus vector expressing mouse oncostatin M induces acute-phase proteins and TIMP-1 expression in vivo in mice. (1999) (35)
- Alveolar Macrophage/Peripheral Blood Monocyte‐Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts (1987) (35)
- FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis (2020) (35)
- Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis (2016) (34)
- Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1 (2010) (34)
- Modulation of pulmonary fibrosis by IL-13Rα2. (2015) (34)
- An adenoviral vector expressing interleukin-4 modulates tumorigenicity and induces regression in a murine breast-cancer model. (1995) (33)
- Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice. (2011) (33)
- Spatial-specific TGF-beta1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung. (1999) (33)
- Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells. (2008) (33)
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- Hemoglobin ontogeny during normal mouse fetal development ( embryonic hemoglobin / adult hemoglobin / yolk sac / fetal liver / tail-short mutation ) (0)
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- Pertussis Toxin to Promote T Cell Entry to-Induced Chemokines Synergize with γ IFN-Gauldie and Trevor (2007) (0)
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- Mechanical Stimulation of FibroticEx VivoLung Strips Activates Latent TGFβ. (2009) (0)
- elastase inhibitor in human neutrophils (1997) (0)
- Fibroblast Growth Factor-1 attenuates TGFβ1-induced lung fibrosis through inhibition of Smad2/3 phosphorylation (2014) (0)
- Tissue Repair In Cystic Fibrosis Lung Disease (2011) (0)
- 4 – Induction of Inflammation: Cytokines and Acute-Phase Proteins (1994) (0)
- Model Regression in a Murine Breast Adenocarcinoma Human IL-2 Induces Complete Tumor the Costimulatory Molecule B 7-1 ( Murine ) and A Double Recombinant Adenovirus Expressing (1998) (0)
- Biographical Sketch of Dr. Alec H. Sehon (1991) (0)
- Increased Fibrocytes In Patients Newly Diagnosed With Idiopathic Pulmonary Fibrosis (2012) (0)
- Altered distribution of alpha1-antitrypsin containing cells in mouse liver and pancreas during acute inflammatory response. Abstr. (1980) (0)
- A Critical Role for Elk1 in Repression of avb6 Integrins and Pulmonary Fibrosis (2014) (0)
- Large-Scale Production of Autologous CD14 + -Monocyte Derived Dendritic Cells Co-Electroporated with Amplified Total Tumour mRNA and Human CD40L mRNA in Patients with B-Cell Chronic Lymphocytic Leukemia. (2006) (0)
- Gene Transfer of Bioactive IL–1ß to the Anterior Chamber of the Rodent Eye Induces a Retinal Phenotype Similar to Human Proliferative Vitreoretinopathy (2005) (0)
- Role of regulatory T cells in S. pneumoniae-induced exacerbation of lung fibrosis in mice (2020) (0)
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