Jack H. Kaplan
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Engineering Computer Science
Jack H. Kaplan's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Jack H. Kaplan's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biochemistry of Na,K-ATPase. (2002) (1072)
- Rapid photolytic release of adenosine 5'-triphosphate from a protected analogue: utilization by the Na:K pump of human red blood cell ghosts. (1978) (570)
- Organization of P-type ATPases: significance of structural diversity. (1995) (463)
- Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation. (1995) (383)
- Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase: genomic organization, alternative splicing, and structure/function predictions. (1994) (349)
- Nitrophenyl-EGTA, a photolabile chelator that selectively binds Ca2+ with high affinity and releases it rapidly upon photolysis. (1994) (276)
- Photolabile chelators for the rapid photorelease of divalent cations. (1988) (273)
- Characterization of a new photoaffinity derivative of ouabain: labeling of the large polypeptide and of a proteolipid component of the Na, K-ATPase. (1978) (252)
- N-terminal Domains of Human Copper-transporting Adenosine Triphosphatases (the Wilson’s and Menkes Disease Proteins) Bind Copper Selectively in Vivo and in Vitro with Stoichiometry of One Copper Per Metal-binding Repeat* (1997) (241)
- Molecular Characterization of hCTR1, the Human Copper Uptake Protein* (2002) (168)
- Na+/Ca2+ exchange and Na+/K+-ATPase in the heart (2015) (161)
- Copper Transport in Mammalian Cells: Special Care for a Metal with Special Needs* (2009) (150)
- An essential role for the extracellular domain of the Na,K-ATPase beta-subunit in cation occlusion. (1993) (146)
- The Mechanism of Copper Uptake Mediated by Human CTR1 (2005) (143)
- How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal (2016) (139)
- Cellular glutathione plays a key role in copper uptake mediated by human copper transporter 1. (2013) (138)
- Chemical modification as an approach to elucidation of sodium pump structure-function relations. (1990) (137)
- Laser photolysis of caged calcium: rates of calcium release by nitrophenyl-EGTA and DM-nitrophen. (1996) (112)
- Functional Properties of the Copper-transporting ATPase ATP7B (The Wilson's Disease Protein) Expressed in Insect Cells* (2002) (101)
- Site-directed Chemical Labeling of Extracellular Loops in a Membrane Protein (2000) (99)
- Inactivation and block of calcium channels by photo-released Ca2+ in dorsal root ganglion neurons. (1988) (97)
- Human Copper Transporter hCTR1 Mediates Basolateral Uptake of Copper into Enterocytes (2007) (92)
- Copper-dependent Recycling of hCTR1, the Human High Affinity Copper Transporter* (2009) (89)
- Flash photolysis of caged compounds: New tools for cellular physiology (1989) (84)
- The sodium pump : recent developments (1991) (82)
- Membrane disposition of the M5-M6 hairpin of Na+,K(+)-ATPase alpha subunit is ligand dependent. (1995) (82)
- O-Linked Glycosylation at Threonine 27 Protects the Copper Transporter hCTR1 from Proteolytic Cleavage in Mammalian Cells* (2007) (82)
- Ion movements through the sodium pump. (1985) (81)
- Photochemical manipulation of divalent cation levels. (1990) (80)
- A new class of photolabile chelators for the rapid release of divalent cations: Generation of caged Ca and caged Mg (1988) (78)
- Stable Plasma Membrane Levels of hCTR1 Mediate Cellular Copper Uptake* (2005) (78)
- Acquisition of dietary copper: a role for anion transporters in intestinal apical copper uptake. (2011) (77)
- Copper transporters and copper chaperones: roles in cardiovascular physiology and disease. (2018) (74)
- Copper entry into human cells: progress and unanswered questions (2007) (73)
- A Re-Evaluation of the Role of hCTR1, the Human High-Affinity Copper Transporter, in Platinum-Drug Entry into Human Cells (2013) (72)
- Unexpected Role of the Copper Transporter ATP7A in PDGF-Induced Vascular Smooth Muscle Cell Migration (2010) (72)
- Glutamate 779, an intramembrane carboxyl, is essential for monovalent cation binding by the Na,K-ATPase. (1994) (71)
- Kinetics of Prephosphorylation Reactions and Myosin Light Chain Phosphorylation in Smooth Muscle (1995) (66)
- Molecular events in close proximity to the membrane associated with the binding of ligands to the Na,K-ATPase. (1994) (65)
- The M4M5 Cytoplasmic Loop of the Na,K-ATPase, Overexpressed in Escherichia coli, Binds Nucleoside Triphosphates with the Same Selectivity as the Intact Native Protein* (1998) (64)
- Urinary Copper Elevation in a Mouse Model of Wilson's Disease Is a Regulated Process to Specifically Decrease the Hepatic Copper Load (2012) (62)
- External Na dependence of ouabain-sensitive ATP: ADP exchange initiated by photolysis of intracellular caged-ATP in human red cell ghosts (1980) (61)
- Arsenate substitutes for phosphate in the human red cell sodium pump and anion exchanger. (1988) (59)
- Heterologous expression of Na(+)-K(+)-ATPase in insect cells: intracellular distribution of pump subunits. (2001) (58)
- Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry (2003) (57)
- Subunit Isoform Selectivity in Assembly of Na,K-ATPase α-β Heterodimers* (2012) (57)
- Location of the carbohydrates present in the HK-ATPase vesicles isolated from hog gastric mucosa. (1990) (57)
- Cell‐Specific Trafficking Suggests a new role for Renal ATP7B in the Intracellular Copper Storage (2009) (53)
- Rate and Regulation of Copper Transport by Human Copper Transporter 1 (hCTR1)* (2013) (53)
- Mutational Analysis of α-β Subunit Interactions in the Delivery of Na,K-ATPase Heterodimers to the Plasma Membrane* (2003) (51)
- Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney. (2008) (51)
- Sidedness of the inhibitory action of disulfonic acids on chloride equilibrium exchange and net transport across the human erythrocyte membrane (1976) (50)
- Domains I and III of the human copper chaperone for superoxide dismutase interact via a cysteine-bridged Dicopper(I) cluster. (2000) (50)
- Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu+ uptake system (2016) (47)
- Handbook of ATPases : biochemistry, cell biology, pathophysiology (2004) (44)
- Evidence for essential carboxyls in the cation-binding domain of the Na,K-ATPase. (1991) (42)
- Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes (2018) (41)
- Expression of an Active Na,K-ATPase with an α-Subunit Lacking All Twenty-three Native Cysteine Residues* (2000) (40)
- The Na:K pump in red cells is electrogenic. (1979) (39)
- Sodium pump-mediated ATP:ADP exchange. The sided effects of sodium and potassium ions (1982) (39)
- Identification of Two Conformationally Sensitive Cysteine Residues at the Extracellular Surface of the Na,K-ATPase α-Subunit* (1997) (38)
- Stabilization of the H,K-ATPase M5M6 Membrane Hairpin by K+ Ions (1999) (38)
- Human Breast Tumor Cells Are More Resistant to Cardiac Glycoside Toxicity Than Non-Tumorigenic Breast Cells (2013) (38)
- Upregulated Copper Transporters in Hypoxia-Induced Pulmonary Hypertension (2014) (37)
- Rate of release of calcium following laser photolysis of the DM-nitrophen-calcium complex (1992) (37)
- An intrinsic membrane glycoprotein with cytosolically oriented n-linked sugars. (1990) (36)
- Carbodiimide inactivation of Na,K-ATPase. A consequence of internal cross-linking and not carboxyl group modification. (1986) (36)
- Chemical modification with dihydro-4,4'-diisothiocyanostilbene-2,2'-disulfonate reveals the distance between K480 and K501 in the ATP-binding domain of the Na,K-ATPase. (1997) (32)
- Hyperplasia of Pancreatic Beta Cells and Improved Glucose Tolerance in Mice Deficient in the FXYD2 Subunit of Na,K-ATPase* (2013) (32)
- Oligomerization of the Na,K-ATPase in Cell Membranes* (2004) (32)
- Human Copper Transporter 1 Lacking O-Linked Glycosylation Is Proteolytically Cleaved in a Rab9-positive Endosomal Compartment* (2009) (31)
- Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface. (2005) (29)
- Interactions between Na,K-ATPase α-Subunit ATP-binding Domains* (2003) (27)
- Structure and function of copper uptake transporters. (2012) (27)
- Inhibition and derivatization of the renal Na,K-ATPase by dihydro-4,4'-diisothiocyanatostilbene-2,2'-disulfonate. (1988) (26)
- Sodium ions and the sodium pump: transport and enzymatic activity. (1983) (25)
- Sodium pump localization in epithelia (2007) (24)
- Mutational analysis of alpha-beta subunit interactions in the delivery of Na,K-ATPase heterodimers to the plasma membrane. (2003) (24)
- Temperature effects on sodium pump phosphoenzyme distribution in human red blood cells (1985) (23)
- ADP SUPPORTS OUABAIN‐SENSITIVE K‐K EXCHANGE IN HUMAN RED BLOOD CELLS * (1982) (23)
- A Moving New Role for the Sodium Pump in Epithelial Cells and Carcinomas (2005) (22)
- Molecular biology of carrier proteins (1993) (22)
- Selective basolateral localization of overexpressed Na-K-ATPase beta1- and beta2- subunits is disrupted by butryate treatment of MDCK cells. (2007) (21)
- Conformational Dynamics of Na+/K+‐ and H+/K+‐ATPase Probed by Voltage Clamp Fluorometry (2003) (21)
- Selective Assembly of Na,K-ATPase α2β2 Heterodimers in the Heart (2016) (21)
- Lasers and flashlamps in research on the mechanism of muscle contraction (1989) (18)
- The sodium pump and hypertension: a physiological role for the cardiac glycoside binding site of the Na,K-ATPase. (2005) (18)
- The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2 (2021) (18)
- Carbodiimide inactivation of Na,K-ATPase, via intramolecular cross-link formation, is due to inhibition of phosphorylation. (1986) (18)
- Evidence of a Role for the Na,K‐ATPase β‐Subunit in Active Cation Transport a (1992) (17)
- Binding of Na+ ions to the Na,K-ATPase increases the reactivity of an essential residue in the ATP binding domain. (1990) (17)
- Modulation of Ca2+ channel selectivity and cardiac contraction by photorelease of Ca2+. (1989) (16)
- Biochemical identification of transmembrane segments of the Ca(2+)-ATPase of sarcoplasmic reticulum. (1994) (16)
- Copper Transporter ATP7A (Copper-Transporting P-Type ATPase/Menkes ATPase) Limits Vascular Inflammation and Aortic Aneurysm Development: Role of MicroRNA-125b. (2019) (16)
- Regulation of Na,K-ATPase Subunit Abundance by Translational Repression* (2009) (15)
- beta-Subunit overexpression alters the stoicheometry of assembled Na-K-ATPase subunits in MDCK cells. (2008) (15)
- P-type ATPases. (1996) (14)
- Inactivation of the Na,K‐ATPase by modification of Lys‐501 with 4‐acetamido‐4′‐isothiocyanatostilbene‐2,2′‐disulfonic acid (SITS) (1992) (14)
- Modification of lysine 501 in Na,K-ATPase reveals coupling between cation occupancy and changes in the ATP binding domain. (1993) (14)
- A monosaccharide is bound to the sodium pump alpha-subunit. (1992) (13)
- Rate of release of Ca2+ following laser photolysis of the DM-nitrophen-Ca2+ complex. (1992) (13)
- Cys577 Is a Conformationally Mobile Residue in the ATP-binding Domain of the Na,K-ATPase α-Subunit* (1999) (13)
- Caged-Ca2+: a new agent allowing liberation of free Ca2+ in biological systems by photolysis. (1989) (12)
- Electrical currents generated by a partially purified Na/Ca exchanger from lobster muscle reconstituted into liposomes and adsorbed on black lipid membranes: Activation by photolysis of caged Ca2+ (1995) (10)
- Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis (2021) (9)
- Photolysis quantum yield measurements in the near-UV; a critical analysis of 1-(2-nitrophenyl)ethyl photochemistry. (2016) (8)
- Interactions between Na,K-ATPase alpha-subunit ATP-binding domains. (2003) (8)
- Structural changes associated with the coupling of ATP hydrolysis and cation transport by the Na pump. (1998) (8)
- N-acetylimidazole inactivates renal Na,K-ATPase by disrupting ATP binding to the catalytic site. (1990) (8)
- A new method for monitoring the kinetics of calcium binding to the sarcoplasmic reticulum Ca(2+)-ATPase employing the flash-photolysis of caged-calcium. (1990) (7)
- Special Topic: Caged Compounds in Cellular Physiology (1990) (7)
- Photolabile Amiloride Derivatives as Cation Site Probes of the Na,K-ATPase (*) (1996) (7)
- Effects of phlorizin on net chloride movements across the valinomycin-treated erythrocyte membrane (1974) (7)
- Heterologous Expression of the Metal‐Binding Domains of Human Copper‐Transporting ATPases (P1‐ATPases) a (1997) (7)
- Title: A Re-evaluation of the Role of hCTR1, the human high affinity Cu transporter in Pt-Drug (2013) (7)
- Conformational Coupling: The Moving Parts of an Ion Pump (2001) (6)
- Mechanics and structure of cross-bridges during contractions initiated by photolysis of caged Ca2+. (1993) (6)
- Calcium‐stimulated sodium efflux from rabbit vascular smooth muscle. (1987) (6)
- Commentary on "Caged Phosphate and the Slips and Misses in Determination of Quantum Yields for Ultraviolet-A-Induced Photouncaging" by G. Gasser and Co-Workers. (2015) (5)
- Na/Na exchange through the Na/K pump of HK sheep erythrocytes (1984) (5)
- Evidence of a role for the Na,K-ATPase beta-subunit in active cation transport. (1992) (5)
- The Stabilization of Cation Binding and its Relation to Na+/K+-ATPase Structure and Function (1994) (5)
- Cys(577) is a conformationally mobile residue in the ATP-binding domain of the Na,K-ATPase alpha-subunit. (1999) (4)
- THE REGULATION OF Na PUMP-MEDIATED ATP: ADP EXCHANGE BY EXTRACELLULAR Na IONS (1981) (4)
- - Subunit overexpression alters the stoicheometry of assembled NaK-ATPase subunits in MDCK cells (2008) (4)
- A natriuretic hormone-binding site on the sodium pump. (2008) (3)
- Ligand‐Induced Conformational Changes in the Na,K‐ATPase α Subunit a (1997) (3)
- Insulin signaling and copper homeostasis are functionally linked in 3T3‐L1 adipocytes (992.2) (2014) (3)
- The vectorial effect of ligands on the occluded intermediate in red cell sodium pump transport. (1988) (3)
- Cation Activation of Na,K-ATPase after Treatment with Thimerosal (1983) (2)
- The sodium pump : structure, mechanism, and regulation : Society of General Physiologists, 44th Annual Symposium, Marine Biological Laboratory, Woods Hole, Massachusetts, 5-9 September, 1990 (1991) (2)
- Photoaffinity labeling of the ouabain binding site of Na,K-ATPase (1978) (2)
- The Na,K-ATPase: A Current Overview (2005) (2)
- Localization of ligand binding from studies of chemical modification. (1991) (2)
- Ion pumps: The view from Gothenburg (1992) (1)
- Proceedings: tasymmetric effects of phlorizin on valinomycin-mediated ion movements across the human erythrocyte membrane. (1974) (1)
- Abstract 15199: Cysteine Oxidation of Cu Importer CTR1 Promotes VEGF Signaling and Angiogenesis (2016) (1)
- Sodium Pump-Catalyzed ATP-ADP Exchange in Red Blood Cells: The Effects of Intracellular and Extracellular Na and K Ions (1983) (1)
- Identification of Glu779 as an Essential Part of the Cation Binding Site of the Sodium Pump (1994) (1)
- Ligand-induced conformational changes in the Na,K-ATPase alpha subunit. (1997) (1)
- Photo-activated inhibition of sulfate equilibrium exchange in human erythrocyte ghosts by a 4-azido-2-nitrobenzoate derivative of phlorizin. (1976) (1)
- Caged ATP as a tool in active transport research. (1986) (1)
- Abstract 16650: Role of Copper Transport Proteins in VSMC Phenotypic Modulation and Vascular Remodeling (2014) (1)
- Erratum: Membrane disposition of the M5-M6 hairpin of Na+,K+-ATPase α subunit is ligand dependent (Proceedings of the National Academy of Sciences of the United States of America (August 15, 1995) 92:17 (7936-7940)) (1995) (1)
- Hypoxia impairs maturation of the Na,K‐ATPase (LB180) (2014) (0)
- Deficient in the FXYD 2 Subunit of Improved Glucose Tolerance in Mice Hyperplasia of Pancreatic Beta Cells and Molecular Bases of Disease : (2013) (0)
- Endothelial Cu Transporter ATP7A deficiency promotes Endothelial-to-mesenchymal Transition and Atherosclerosis via inducing Metabolic Reprogramming (2022) (0)
- Abstract 13610: Endothelial Cu Transporter Atp7a Promotes Vegfr2 Signaling and Post-ischemic Neovascularization via Regulating Autophagy (2020) (0)
- Abstract 10973: Sulfenylation of Copper Importer CTR1 Drives Redox-Dependent VEGFR2 Internalization and Angiogenesis Required for Reparative Neovascularization (2018) (0)
- Abstract 813: Mechanism of cellular uptake of Pt drugs: The role of hCTR1 (2012) (0)
- Abstract 10910: Cu Importer CTR1 is a Redox Sensor That Promotes VEGFR2 Signaling and Angiogenesis (2019) (0)
- Cysteine Oxidation of Cu Uptake Transporter CTR1 Protects Against Atherosclerosis via limiting Endothelial Senescence (2022) (0)
- Turnover Rate and Cell Copy Number of Over-Expressed and Endogenous hCTR1, the Human High Affinity Cu Transporter (2011) (0)
- Erratum: Ion pumps-structure and mechanism (Acta Physiologica Scandinavica, Vol. 146, Supplementum 607, 1992) (1992) (0)
- Abundance by Translational Repression Regulation of Na,K-ATPase Subunit and Biogenesis: Membrane Transport, Structure, Function, (2014) (0)
- Introduction: A Close Look at an Ion Pump (2001) (0)
- Related Cation Pumps: Structures, Mechanisms, and (2006) (0)
- Active Transport of Sodium and Potassium (2020) (0)
- A New Class of Photolabile Chelators for the Rapid Release of Divalent Cations: Generation of Caged Ca and Caged Mg. (1988) (0)
- Whole-Transcriptome Sequencing Analyses of Nuclear Antixoxidant-1 in Endothelial Cells: Role in Inflammation and Atherosclerosis (2022) (0)
- Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis (2022) (0)
- Copper Transporter ATP7A Limits Vascular Inflammation and Aortic Aneurysm Development: Role of miR-125b (2019) (0)
- Characterization of Mutant hCTR1 Copper Transporters Truncated by Proteolytic Cleavage in the Absence of O-Linked Glycosylation at Thr27 (2010) (0)
- M-AM-Syml-l CLASSES and FUNCTIONS of CALCIUM WAVES (2005) (0)
- X-ray absorption studies of copper chaperones (2003) (0)
- Status Report on the SDSS-II Supernova Survey (2005) (0)
- Mutational Analysis of (cid:1) - (cid:2) Subunit Interactions in the Delivery of Na,K-ATPase Heterodimers to the Plasma Membrane* (2003) (0)
- Mutational analysis of the interactions of the alpha and beta subunits of the Na,K-ATPase. (2003) (0)
- Lost in Translation: Regulation of Na Pump Subunit Abundance (2010) (0)
- Robert H. Costa: In Memoriam (1957-2006) (2006) (0)
- Cation pulses to investigate biological systems (1991) (0)
- Rearrangements of the membrane-associated segments of Na+/K+ -ATPase upon phosphorylation, ion-occlusion and ouabain binding (1994) (0)
- Assessing Student Status and Progress in Science Reasoning and Quantitative Literacy at a Very Large Undergraduate Institution (2009) (0)
- Interaction of the Na,K-ATPase with H2DIDS. (1988) (0)
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