Jacobus Hubertus van Boom

Jacobus Hubertus van Boom's AcademicInfluence.com Rankings

Law

#2611

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#3248

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International Law

#639

World Rank

#791

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Jacobus Hubertus van Boom's Degrees

PhD Law University of Amsterdam

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Jacobus Hubertus van Boom's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. (1990) (527)
Left-handed double helical DNA: variations in the backbone conformation. (1981) (460)
A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides. (1986) (345)
Identification of an RNA Hairpin in Poliovirus RNA That Serves as the Primary Template in the In Vitro Uridylylation of VPg (2000) (311)
Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). (1980) (287)
The molecular structure of a DNA-triostin A complex. (1984) (224)
The conformation of neurotensin bound to its G protein-coupled receptor (2003) (206)
Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy. (1984) (203)
Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations. (1985) (195)
The tRNA-like structure at the 3' terminus of turnip yellow mosaic virus RNA. Differences and similarities with canonical tRNA. (1982) (176)
Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis. (1995) (176)
Genetic and Biochemical Studies of Polioviruscis-Acting Replication Element cre in Relation to VPg Uridylylation (2000) (172)
Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides. (2003) (166)
Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA. (1982) (159)
Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study. (1991) (159)
Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization. (1984) (157)
A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment. (1985) (156)
Copper-dependent cleavage of DNA by bleomycin. (1987) (147)
Molecular structure of the octamer d(G-G-C-C-G-G-C-C): modified A-DNA. (2011) (145)
Topogenesis of microbody enzymes: a sequence comparison of the genes for the glycosomal (microbody) and cytosolic phosphoglycerate kinases of Trypanosoma brucei. (1985) (142)
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. (1982) (133)
Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment. (1989) (131)
On loop folding in nucleic acid hairpin-type structures. (1986) (131)
Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor. (1999) (128)
Secondary chemical shifts in immobilized peptides and proteins: A qualitative basis for structure refinement under Magic Angle Spinning (2001) (128)
A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy. (2005) (128)
The tetramer d(CpGpCpG) crystallizes as a left-handed double helix. (1980) (127)
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei. (1997) (123)
Synthesis of cluster galactosides with high affinity for the hepatic asialoglycoprotein receptor. (1995) (122)
Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. (1994) (122)
Triple helix formation by oligopurine-oligopyrimidine DNA fragments. Electrophoretic and thermodynamic behavior. (1990) (118)
Effects of base sequence on the loop folding in DNA hairpins. (1989) (115)
Thioglycuronides: synthesis and application in the assembly of acidic oligosaccharides. (2004) (115)
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein. (1991) (113)
Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. (1995) (113)
Non-Watson-Crick G.C and A.T base pairs in a DNA-antibiotic complex. (1986) (109)
High‐affinity binding of a synthetic heptaglucoside and fungal glucan phytoalexin elicitors to soybean membranes (1990) (108)
The sequence of the gene for cytochrome c oxidase subunit I, a frameshift containing gene for cytochrome c oxidase subunit II and seven unassigned reading frames in Trypanosoma brucei mitochondrial maxi-circle DNA. (1984) (107)
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene. (1986) (100)
A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution. (1984) (98)
The effect of single base-pair mismatches on the duplex stability of d(T-A-T-T-A-A-T-A-T-C-A-A-G-T-T-G) . d(C-A-A-C-T-T-G-A-T-A-T-T-A-A-T-A). (1984) (98)
Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258. (1994) (97)
Structure, kinetics and thermodynamics of DNA hairpin fragments in solution. (1983) (96)
Site-specific cleavage of RNA by Fe(II).bleomycin. (1990) (95)
1H NMR study of the exchangeable protons of the duplex d(GCGTTGCG).d(CGCAACGC) containing a thymine photodimer. (1987) (95)
(1----5)-linked beta-D-galactofuranosides are immunodominant in extracellular polysaccharides of Penicillium and Aspergillus species. (1988) (91)
Hairpin formation in synthetic oligonucleotides. (1985) (91)
Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin. (1993) (91)
Biochemical and Genetic Studies of the VPg Uridylylation Reaction Catalyzed by the RNA Polymerase of Poliovirus (2003) (90)
Vasopressin and oxytocin mRNA regulation in the rat assessed by hybridization with synthetic oligonucleotides. (1983) (90)
Transglycosidase Activity of Chitotriosidase (2003) (87)
Raman spectra of single crystals of r(GCG)d(CGC) and d(CCCCGGGG) as models for A DNA, their structure transitions in aqueous solution, and comparison with double-helical poly(dG).poly(dC). (1986) (87)
Antitumor drug nogalamycin binds DNA in both grooves simultaneously: molecular structure of nogalamycin-DNA complex. (1989) (86)
Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei. (1983) (85)
Fibrinogen lysine residue A alpha 157 plays a crucial role in the fibrin-induced acceleration of plasminogen activation, catalyzed by tissue-type plasminogen activator. (1987) (85)
Complex of lac repressor headpiece with a 14 base-pair lac operator fragment studied by two-dimensional nuclear magnetic resonance. (1987) (82)
Unusual DNA conformation at low pH revealed by NMR: parallel-stranded DNA duplex with homo base pairs. (1992) (79)
Crystal and solution structures of the B-DNA dodecamer d(CGCAAATTTGCG) probed by Raman spectroscopy: heterogeneity in the crystal structure does not persist in the solution structure. (1988) (78)
Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells. (1992) (78)
Structure of nogalamycin bound to a DNA hexamer. (1990) (78)
Lysis gene of bacteriophage MS2 is activated by translation termination at the overlapping coat gene. (1987) (77)
Transition metal derivatives of peptide nucleic acid (PNA) oligomers-synthesis, characterization, and DNA binding. (2000) (74)
Crystal structure of Z-DNA without an alternating purine-pyrimidine sequence. (1985) (72)
The modified base J is the target for a nove lDNA‐binding protein in kinetoplastid protozoans (1999) (71)
Sequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors. (2003) (71)
Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells. (1990) (70)
The three-dimensional structure of a DNA hairpin in solution two-dimensional NMR studies and structural analysis of d(ATCCTATTTATAGGAT). (1991) (68)
Basepairing potential of the 3' terminus of 16S RNA: dependence on the functional state of the 30S subunit and the presence of protein S21. (1981) (68)
Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex. (1993) (65)
Conformational characteristics of the trinucleoside diphosphate dApdApdA and its constituents from nuclear magnetic resonance and circular dichroism studies. Extrapolation to the stacked conformers. (1980) (65)
The Raman spectra of left-handed DNA oligomers incorporating adenine-thymine base pairs+. (1984) (65)
Complete nucleotide sequence of alfalfa mosaic virus RNA 2. (1983) (64)
Heteronuclear Scalar Couplings in the Bases and Sugar Rings of Nucleic Acids: Their Determination and Application in Assignment and Conformational Analysis (1996) (63)
Application of 2-cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite for in situ preparation of deoxyribonucleoside phosphoramidites and their use in polymer-supported synthesis of oligodeoxyribonucleotides. (1986) (63)
Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex. (1989) (62)
Molecular structure of nicked DNA: a substrate for DNA repair enzymes. (1990) (61)
Conformational changes in the oligonucleotide duplex d(GCGTTGCG) x d(CGCAACGC) induced by formation of a cis-syn thymine dimer. A two-dimensional NMR study. (1987) (60)
Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys (1992) (60)
Z-DNA forms without an alternating purine-pyrimidine sequence in solution. (1985) (60)
cis-diamminedichloroplatinum(II) induced distortion of a single and double stranded deoxydecanucleosidenonaphosphate studied by nuclear magnetic resonance. (1985) (59)
Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG). (1988) (59)
Circular dichroism study of stacking properties of oligodeoxyadenylates and polydeoxyadenylate. A three-state conformational model. (1981) (58)
Synthesis of potent agonists of the D-myo-inositol 1,4, 5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A. (2000) (58)
Polymer supported DNA synthesis using hydroxybenzotriazole activated phosphotriester intermediates. (1984) (58)
Oligodeoxynucleotide folding in solution: loop size and stability of B-hairpins. (1988) (57)
Structure determination of a DNA octamer in solution by NMR spectroscopy. Effect of fast local motions. (1991) (56)
Conformational analysis of a hybrid DNA-RNA double helical oligonucleotide in aqueous solution: d(CG)r(CG)d(CG) studied by 1D- and 2D-1H NMR spectroscopy. (1983) (56)
Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics. (2000) (56)
Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method. (1977) (55)
Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. (1990) (55)
The solution structure of a RNA pentadecamer comprising the anticodon loop and stem of yeast tRNAPhe. A 500 MHz 1H-n.m.r. study. (1984) (52)
Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen. (2004) (51)
Analogs of (2'-5')oligo(A). Endonuclease activation and inhibition of protein synthesis in intact cells. (1981) (51)
H NMR study of a complex between the lac repressor headpiece and a 22 base pair symmetric lac operator. (1989) (51)
Molecular structure of an A-DNA decamer d(ACCGGCCGGT). (1989) (50)
Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis. (2001) (50)
Studies on the attenuation phenotype of polio vaccines: poliovirus RNA polymerase derived from Sabin type 1 sequence is temperature sensitive in the uridylylation of VPg. (2000) (49)
lac Repressor headpiece binds specifically to half of the lac operator: a proton nuclear magnetic resonance study. (1983) (46)
A Rapid and Reliable Method for the Detection of Molds in Foods: Using the Latex Agglutination Assay. (1989) (46)
Double-resonance experiments at 500 MHz on gene-5 protein and its complex with octadeoxyriboadenylic acid. (1981) (46)
A short route toward chiral, polyhydroxylated indolizidines and quinolizidines. (2003) (46)
DNA hairpin loops in solution. Correlation between primary structure, thermostability and reactivity with single-strand-specific nuclease from mung bean. (1991) (46)
Molecular cloning and characterization of a complete DNA copy of potato spindle tuber viroid RNA. (1982) (46)
Methylation of the EcoRI recognition site does not alter DNA conformation: the crystal structure of d(CGCGAm6ATTCGCG) at 2.0-A resolution. (1989) (45)
A water-soluble cholesteryl-containing trisgalactoside: synthesis, properties, and use in directing lipid-containing particles to the liver. (1984) (45)
Discrimination between A-type and B-type conformations of double helical nucleic acid fragments in solution by means of two-dimensional nuclear Overhauser experiments. (1984) (45)
Purification and properties of extracellular polysaccharide (EPS) antigens produced by different mould species. (1987) (44)
Hairpin and duplex formation of the DNA octamer d(m5C-G-m5C-G-T-G-m5C-G) in solution. An NMR study. (1986) (44)
Minimal oligosaccharide structures required for induction of immune responses against meningococcal immunotype L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates (1991) (44)
Structural influence of RNA incorporation in DNA: quantitative nuclear magnetic resonance refinement of d(CG)r(CG)d(CG) and d(CG)r(C)d(TAGCG). (1993) (42)
A 500-MHz proton nuclear magnetic resonance study of the structure and structural alterations of gene-5 protein-oligo(deoxyadenylic acid) complexes. (1983) (42)
Carbon-13 NMR in conformational analysis of nucleic acid fragments. 4. The torsion angle distribution about the C3'-O3' bond in DNA constituents. (1985) (42)
Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA. (1996) (42)
Construction of viable and lethal mutations in the origin of bacteriophage 'phi' X174 using synthetic oligodeoxyribonucleotides. (1981) (42)
Evidence for the involvement of a small subregion of the endoplasmic reticulum in the inositol trisphosphate receptor-induced activation of Ca2+ inflow in rat hepatocytes. (1999) (41)
Molecular structure of the netropsin-d(CGCGATATCGCG) complex: DNA conformation in an alternating AT segment. (2011) (41)
Structural features of the DNA hairpin d(ATCCTA-GTTA-TAGGAT): formation of a G-A base pair in the loop. (1997) (41)
Targeted Lysosome Disruptive Elements for Improvement of Parenchymal Liver Cell-specific Gene Delivery* (2002) (40)
Cyclic diguanylic acid behaves as a host molecule for planar intercalators (1990) (40)
Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors. (2003) (40)
Influence of the base sequence on the conformational behaviour of DNA polynucleotides in solution. (1987) (40)
Recycling glycoproteins do not return to the cis-Golgi (1988) (39)
Solution conformation of an oligonucleotide containing a G.G mismatch determined by nuclear magnetic resonance and molecular mechanics. (1991) (38)
A practical synthesis of gramicidin s and sugar amino Acid containing analogues. (2004) (38)
Hairpin structures in DNA containing arabinofuranosylcytosine. A combination of nuclear magnetic resonance and molecular dynamics. (1990) (38)
Heteronuclear NMR of DNA with the heteronucleus in natural abundance: facilitated assignment and extraction of coupling constants. (1992) (38)
Assignment of non-exchangeable base proton and H1' resonances of a deoxyoctanucleoside heptaphosphate d(G-G-C*-C*-G-G-C-C) by using the nuclear Overhauser effect. (1983) (38)
Effects of the O2' hydroxyl group on Z-DNA conformation: structure of Z-RNA and (araC)-[Z-DNA]. (1989) (38)
Backbone and side chain dynamics of lac repressor headpiece (1-56) and its complex with DNA. (1997) (37)
Assessment of high-affinity hybridization, RNase H cleavage, and covalent linkage in translation arrest by antisense oligonucleotides. (1998) (37)
Conformational analysis of the nucleotides A2'-5'A, A2'-5'A2'-5'A and A2'-5'U from nuclear magnetic resonance and circular dichroism studies. (1981) (37)
An NMR study of polymorphous behaviour of the mismatched DNA octamer d(m5C-G-m5C-G-A-G-m5C-G) in solution. The B-duplex and hairpin forms. (1987) (36)
Protein-conjugated synthetic di- and trisaccharides of pneumococcal type 17F exhibit a different immunogenicity and antigenicity than tetrasaccharide. (1993) (36)
The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system. (2002) (36)
Proton NMR studies on the covalently linked RNA-DNA hybrid r(GCG)d(TATACGC). Assignment of proton resonances by application of the nuclear Overhauser effect. (1983) (35)
Solid-phase synthesis of polymyxin B1 and analogues via a safety-catch approach. (2003) (35)
A general method for the synthesis of 5'-monophosphates of DNA fragments via phosphotriester intermediates. (1982) (35)
Conformational and thermodynamic consequences of the introduction of a nick in duplexed DNA fragments: an NMR study augmented by biochemical experiments. (1989) (34)
Bulge-out structures in the single-stranded trimer AUA and in the duplex (CUGGUGCGG).(CCGCCCAG). A model-building and NMR study. (1988) (34)
Recognition of Base J in Duplex DNA by J-binding Protein* (2002) (34)
Sequence-dependent structural variation in single-helical DNA. Proton NMR studies of d(T-A-T-A) and d(A-T-A-T) in aqueous solution. (1984) (33)
Iodonium ion-assisted synthesis of a haptenic tetrasaccharide fragment corresponding to the inner cell-wall glycopeptidolipid of Mycobacterium avium serotype 4. (1993) (33)
New structural features of the antigenic extracellular polysaccharides of Penicillium and Aspergillus species revealed with exo-beta-D-galactofuranosidase (1992) (33)
Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum(II) complexes. (2003) (33)
cis-Platinum induced distortions in DNA. Conformational analysis of d(GpCpG) and cis-pt(NH3)2[d(GpCpG)], studied by 500-MHz NMR. (1983) (33)
1H NMR studies of the binding of bacteriophage-M13-encoded gene-5 protein to oligo(deoxyadenylic acid)s of varying length. (1982) (33)
Synthesis of cyclic oligonucleotides by a modified phosphotriester approach. (1988) (32)
Role of nucleotide excision repair in processing of O4-alkylthymines in human cells. (1994) (32)
Molecular structure of a DNA decamber containing an anticancer nucleoside arabinosylcytosine: conformational perturbation by arabinosylcytosine in B-DNA. (1991) (32)
The transition from a neutral-pH double helix to a low-pH triple helix induces a conformational switch in the CCCG tetraloop closing a Watson-Crick stem. (1996) (32)
Extra thymidine stacks into the d(CTGGTGCGG).d(CCGCCCAG) duplex. An NMR and model-building study. (1988) (32)
NMR studies and conformational analysis of a DNA four-way junction formed in a linear synthetic oligonucleotide. (1994) (31)
Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus RNAs and the intercistronic junction in RNA 3. (1980) (31)
An NMR study of the polymorphous behavior of the mismatched DNA octamer d(m5C-G-m5C-G-T-G-m5C-G) in solution. The B, Z, and hairpin forms. (1987) (31)
Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids. (2002) (31)
Conformational analysis of r(CGCGCG) in aqueous solution: an A-type double helical conformation studied by two-dimensional nuclear Overhauser effect spectroscopy. (1984) (31)
Influence of N6-methylation of residue A(5) on the conformational behaviour of d(C-C-G-A-A-T-T-C-G-G) in solution studied by 1H-NMR spectroscopy. 2. The hairpin form. (1987) (31)
Molecular structure of cyclic deoxydiadenylic acid at atomic resolution. (1988) (30)
Synthesis and elaboration of functionalised carbohydrate-derived spiroketals. (2004) (29)
Effect of the G.T mismatch on backbone and sugar conformations of Z-DNA and B-DNA: analysis by Raman spectroscopy of crystal and solution structures of d(CGCGTG) and d(CGCGCG). (1989) (29)
NMR studies of DNA three-way junctions containing two unpaired thymidine bases: the influence of the sequence at the junction on the stability of the stacking conformers. (1996) (29)
Role of 16-S RNA in ribosome messenger recognition. (1980) (29)
Exploring the DNA binding domain of gene V protein encoded by bacteriophage M13 with the aid of spin-labeled oligonucleotides in combination with 1H-NMR. (1993) (29)
Solution structure of the 3'-5' cyclic dinucleotide d(pApA). A combined NMR, UV melting, and molecular mechanics study. (1988) (29)
NMR studies on the binding of antitumor drug nogalamycin to DNA hexamer d(CGTACG). (1990) (29)
Characterization of the promoter of the large ribosomal RNA gene in yeast mitochondria and separation of mitochondrial RNA polymerase into two different functional components. (1986) (28)
Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes. (2002) (28)
Synthesis of nucleic acid methylphosphonates via the 1-hydroxybenzotriazole phosphotriester approach. (1986) (28)
The synthesis of oligoribonucleotides. Part XI. Preparation of ribonucleoside 2'-acetal 3'-esters by selective deacylation. (1975) (28)
Conformational analysis of a DNA triplet in aqueous solution. Thymidylyl-(3'-5')-thymidylyl-(3'-5')-2'-deoxyadenosine, d(T-T-A), studied by 1H nuclear magnetic resonance at 360 MHz. (1976) (28)
The use of a mannitol-derived fused oxacycle as a combinatorial scaffold. (2003) (28)
The B-Z conformational transition in folded oligodeoxynucleotides: loop size and stability of Z-hairpins. (1988) (27)
Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action. (1999) (27)
Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct. (1992) (27)
The cholesterol derivative of a triantennary galactoside with high affinity for hepatic asialoglycoprotein receptor: a potent cholesterol lowering agent. (1995) (27)
Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents. (1995) (27)
A phosphorus NMR study of the reaction products of cis‐diamminedichloroplatinum (II) with a double‐helical oligonucleotide and with DNA (1984) (27)
Substrate specificity and kinetic studies of nodulation protein NodL of Rhizobium leguminosarum. (1995) (26)
N-myristyl-Lys-Arg-Thr-Leu-Arg: a novel protein kinase C inhibitor. (1990) (26)
Oligonucleotide-directed mutagenesis of gene IX of bacteriophage M13. (1982) (25)
Synthesis and biological evaluation of novel turn-modified gramicidin S analogues. (2003) (25)
Synthesis of a substrate of protein kinase C and its corresponding phosphopeptide. (2009) (25)
A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates. (1987) (25)
Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases. (2004) (25)
Use of a 1-hydroxybenzotriazole activated phosphorylating reagent towards the synthesis of short RNA fragments in solution. (1986) (25)
Stereoselective transformations on D-glucose-derived eight-membered ring carbocycles. (2001) (25)
Complete assignment and conformational analysis of a deoxyribotetranucleotide. d(TAAT). A 360 and 500 Mhz NMR study. (1981) (25)
Conformational analysis of the octamer d(G-G-C-C-G-G-C-C) in aqueous solution. A one-dimensional and two-dimensional proton NMR study at 300 MHz and 500 MHz. (1986) (25)
Right-handed and left-handed double-helical DNA: structural studies. (1983) (24)
Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs. (1986) (24)
Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. (1990) (24)
Conformational analysis of a modified ribotetranucleoside triphosphate: m6(2)A-U-m6(2)A-U studied in aqueous solution by nuclear magnetic resonance at 500 MHz. (1981) (24)
Synthesis of short RNA fragments by the benzotriazolyl phosphotriester approach. (1983) (24)
Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: a new generation of potential antisense drugs. (2002) (24)
Neighbouring group participation in the unblocking of phosphotriesters of nucleic acids. (1979) (24)
Glutathione analogues as novel inhibitors of rat and human glutathione S-transferase isoenzymes, as well as of glutathione conjugation in isolated rat hepatocytes and in the rat in vivo. (1995) (24)
Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution. (1993) (23)
The crystal structure of d(GGm5CCGGCC): The effect of methylation on A‐DNA structure and stability (1987) (23)
One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides. (2002) (23)
Synthesis of isotope labeled oligonucleotides and their use in an NMR study of a protein-DNA complex. (1992) (23)
The B and Z forms of the d(m5C-G)3 and d(br5C-G)3 hexamers in solution. A 300-MHz and 500-MHz two-dimensional NMR study. (1986) (23)
Assignment of the 1H-NMR spectrum of a lac repressor headpiece-operator complex in H2O and identification of NOEs. Consequences for protein-DNA interaction. (1990) (23)
Use of a synthetic DNA oligonucleotide to probe the precision of RNA splicing in a yeast mitochondrial petite mutant. (1981) (23)
A short phosphodiester window is sufficient to direct RNase H-dependent RNA cleavage by antisense peptide nucleic acid. (2000) (23)
2,5-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L. (1999) (23)
Fourth rank immobile nucleic acid junctions. (1983) (23)
Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes. (1990) (22)
dC-dG alternating oligonucleotides: thermodynamic and kinetic aspects of the B-Z transformation. (1987) (22)
Conformational analysis of the single-helical DNA fragment d(T-A-A-T) in aqueous solution. The combined use of NMR proton chemical shifts and coupling constants obtained at 300 MHz and 500 MHz. (1984) (22)
The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling. (1998) (22)
Synthesis of the nucleopeptides H-Phe-Tyr(pGC)-NH2 and H-Phe-Ser(pGC)-Ala-OH via a phosphotriester approach. (1989) (21)
1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element. (1991) (21)
On the chemistry of RNA degradation by Fe.bleomycin. (1997) (21)
Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy. (1999) (21)
Helix opening in deoxyribonucleic acid from a proton nuclear magnetic resonance study of imino and amino protons in d(CG)3. (1984) (21)
Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2'-deoxyguanosine. (1991) (21)
Site-specific Interactions of JBP with Base and Sugar Moieties in Duplex J-DNA (2002) (20)
2'-5'-Linked oligo(adenylic acid) and its analogs. A new class of inhibitors of mRNA methylation. (1982) (20)
Complexes of DNA hairpins and a single-stranded oligonucleotide detected by affinity chromatography and mung bean nuclease cleavage. (1987) (20)
Restoration of the biological activity of in vitro synthesized øX DNA by transfection of ung — spheroplasts or dUTPase treatment (1980) (19)
Solid-phase synthesis of an RNA nucleopeptide fragment from the nucleoprotein of poliovirus. (1992) (19)
Conformation and dynamics of short DNA duplexes: (dC-dG)3 and (dC-dG)4. (1984) (19)
Synthesis of a pentasaccharide corresponding to the repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar D. (1996) (19)
Synthesis of riboguanosine pentaphosphate ppprGpp (Magic Spot II) via a phosphotriester approach. (1985) (18)
The application of the AMB protective group in the solid-phase synthesis of methylphosphonate DNA analogues. (1993) (18)
In vitro site-directed mutagenesis with synthetic DNA oligonucleotides yields unexpected deletions and insertions at high frequency. (1983) (18)
Nuclear magnetic resonance studies of codon-anticodon interaction in tRNAPhe. I. Effect of binding complementary tetra and pentanucleotides to the anticodon. (1980) (18)
Optimization of the binding properties of PNA-(5')-DNA chimerae. (1998) (17)
Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model. (2004) (17)
Chemical synthesis of a messenger ribonucleic acid fragment: AUGUUCUUCUUCUUCUUC. (1982) (17)
Conformational analysis of the single-stranded ribonucleic acid A-A-C-C. A one-dimensional and two-dimensional proton NMR study at 500 MHz. (1983) (17)
Proton NMR study and conformational analysis of d(CGT), d(TCG) and d(CGTCG) in aqueous solution. The effect of a dangling thymidine and of a thymidine mismatch on DNA mini-duplexes. (1984) (17)
Effect of Bulky Lesions on DNA (2004) (17)
Comparison of the conformation of an oligonucleotide containing a central G-T base pair with the non-mismatch sequence by proton NMR. (1987) (17)
Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine. (2004) (17)
Construction and characterization of recombinant plasmid DNAs containing sequences of the origin of bacteriophage phi X174 DNA replication. (1981) (17)
Assignment strategies and analysis of cross-peak patterns and intensities in the three-dimensional homonuclear TOCSY-NOESY of RNA. (1994) (17)
31P-NMR analysis of the B to Z transition in double-stranded (dC-dG)3 and (dC-dG)4 in high salt solution. (1984) (16)
Polyamine interaction with Z-DNA. (1989) (16)
Synthesis and proton-NMR studies of oligonucleotides containing an apurinic (AP) site. (1987) (16)
Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein: farnesyl transferase. (1999) (16)
1H NMR studies of lac-operator DNA fragments. (1981) (16)
Codon-anticodon interaction in tRNAPhe. II. A nuclear magnetic resonance study of the binding of the codon UUC. (1980) (16)
Hairpin structures in synthetic oligodeoxynucleotides: sequence effects on the duplex-to-hairpin transition. (1989) (15)
Design and synthesis of a multivalent homing device for targeting to murine CD22. (2001) (15)
The interaction of peptide-tethered platinum(II) complexes with DNA. (2003) (15)
Gene A protein cleavage of recombinant plasmids containing the phi X174 replication origin. (1984) (15)
Crystallization of complexes of EcoRV endonuclease with cognate and non-cognate DNA fragments. (1991) (14)
A facile duplex-hairpin interconversion through a cruciform intermediate in a linear DNA fragment. (1989) (14)
A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes. (2003) (14)
Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells. (1989) (14)
Unambiguous structure characterization of a DNA-RNA triple helix by 15N- and 13C-filtered NOESY spectroscopy. (1996) (13)
Spirophostins: conformationally restricted analogues of adenophostin A. (2000) (13)
1,3-Dimethyllumazine derivatives from Limnatis nilotica. (2005) (13)
Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors. (2002) (13)
A novel strategy towards the synthesis of orthogonally functionalised 4-aminoglycosides. (2003) (13)
Preparation of the individual diastereomers of adenylyl-(2'-5')-P-thioadenylyl-(2'-5')-adenosine and their 5'-phosphorylated derivatives. (1987) (13)
Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1. (2004) (13)
Synthesis of nucleic acid methylphosphonothioates. (1988) (13)
Synthesis and conformational analysis of synthetic DNA fragments. (1983) (13)
Influence of uracil on the conformational behaviour of RNA oligonucleotides in solution. (1988) (12)
Downregulation of c-Ki-ras promoter activity by triplex-forming oligonucleotides endogenously generated in human 293 cells. (2000) (12)
Synthesis of a trisaccharide of the inner core region of Citrobacter PCM 187 lipopolysaccharide that contains L-glycero-alpha-D-manno-heptopyranosyl units. (1989) (12)
Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains. (1999) (12)
The interaction of lac repressor headpiece with its operator: an NMR view. (1988) (11)
A monogalactosylated cholesterol derivative that specifically induces uptake of LDL by the liver. (1992) (11)
Selective Cross‐Metathesis of C‐Allyl‐Glycosides (2005) (11)
Synthesis of ppTppp via phosphotriester intermediates. (1983) (11)
Conformation of ribooligonucleotide duplexes containing an alternating C-G sequence which show an unusual circular dichroism spectrum. (1984) (11)
2-O-methyl-D-mannose residues are immunodominant in extracellular polysaccharides of Mucor racemosus and related molds. (1994) (11)
Oligonucleotide binding to the coat protein disk of tobacco mosaic virus. Possible steps in the mechanism of assembly. (1986) (11)
Revised interpretation of the immunological results obtained with pneumococcal polysaccharide 17F derived synthetic di-, tri- and tetrasaccharide conjugates in mice and rabbits. (2001) (11)
Solid-phase synthesis of a cell-wall component of Haemophilus (Actinobacillus) pleuropneumoniae serotype 2. (1990) (10)
Conformational analysis of the dinucleotides 5'-methylphospho-N6-dimethyladenylyl-uridine (mpm62A-U) and 5'methylphospho-uridylyl-N6-dimethyladenosine (mpU-m62A) and of the trinucleotide U-m62A-U. A nuclear magnetic resonance and circular dichroic study. (1988) (10)
Conformational characteristics of the hexanucleoside pentaphosphate AUAUAU: a 2D NMR study at 500 MHz. (1985) (9)
From α‐1,2‐Anhydrosugars to C‐Glycosides: The Influence of Lewis Acids and Nucleophiles on the Stereochemistry (2003) (9)
Synthesis of Highly Functionalized Piperidines via a Tandem Retro‐Michael‐[2 + 3]‐Cycloaddition (2003) (9)
Solution structure of an oncogenic DNA duplex containing a G.A mismatch. (1991) (9)
Thermodynamics of the various forms of the dodecamer d(ATTACCGGTAAT) and of its constituent hexamers from proton nmr chemical shifts and UV melting curves: Three‐state and four‐state thermodynamic models (1989) (9)
Water-soluble cholesteryl-containing phosphorothioate monogalactosides: synthesis, properties, and use in lowering blood cholesterol by directing plasma lipoproteins to the liver. (1991) (9)
Synthesis of racemic 5-phosphonate analogues of myo-inositol 1,4,5-tris- and 1,3,4,5-tetrakis-phosphate. (1992) (9)
Isoenzyme-selective inhibition of glutathione conjugation in vivo: selective inhibition of the conjugation of S-2-Bromoisovalerylurea in the rat. (1996) (8)
Preparation, antigenicity, and immunogenicity of synthetic ribosylribitol phosphate oligomer-protein conjugates and their potential use for vaccination against Haemophilus influenzae type b disease. (1992) (8)
Interactions between a symmetrical minor groove binding compound and DNA oligonucleotides: 1H and 19F NMR studies. (1989) (8)
The synthesis of oligoribonucleotides. X. Preparation of 2',3'-cyclic phosphates of ribonucleosides and diribonucleoside phosphates via phosphotriester intermediates. (1973) (8)
Detection of fungal carbohydrate antigens by high-performance immunoaffinity chromatography using a protein A column with covalently linked immunoglobulin G. (1992) (8)
Synthesis of 3'-phosphates of diribonucleoside monophosphates via phosphotriester intermediates. (1976) (7)
Photoreactivation of the thymine dimer containing DNA octamer d(GCGTTGCG).d(CGCAACGC) by the photoreactivating enzyme from Anacystis nidulans. (1988) (7)
Confirmation of the D configuration of the 2-substituted arabinitol 1-phosphate residue in the capsular polysaccharide from Streptococcus pneumoniae Type 17F. (2002) (7)
Verification of the position of the phosphate group in some synthetic phosphopeptides by fast-atom bombardment and tandem mass spectrometry. (1993) (7)
Conformational aspects of an uncharged phosphate analogon built in at the branch-point of a DNA four-way junction. (1996) (7)
Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improves the 3'-exonuclease stability of 2'-5'-oligoadenylate-antisense conjugates. (2000) (7)
Synthesis and RNase L Binding and Activation of a 2-5A-(5′)-DNA-(3′)-PNA Chimera, a Novel Potential Antisense Molecule (2000) (7)
Selective inhibition of glucuronidation by 2,2,2-triphenylethyl-UDP in isolated rat hepatocytes: conjugation of harmol, 3,3',5-triiodothyronine, and N-hydroxy-2-acetylaminofluorene. (1991) (7)
The left-handed Z-DNA conformation in oligodeoxynucleotides containing different amounts of AT base pairs: a far UV circular dichroism study. (1989) (6)
Preparation of covalently linked DNA-RNA hybrids and arabinocytidine containing DNA fragments. (1988) (6)
Inhibition of glutathione conjugation by glutathione analogues in the perfused rat liver. Effect of esterification on the potency of gamma-L-glutamyl-alpha-(D-2-aminoadipyl)-N-2-heptylamine. (1997) (6)
Structural effects of the C2-methylhypoxanthine:cytosine base pair in B-DNA: A combined NMR and X-ray diffraction study of d(CGC[m2I]AATTCGCG). (1993) (6)
3′‐O‐Methylated analogs of 2–5A as inhibitors of virus replication (1983) (5)
Guanine-06 methylation reduces the reactivity of d(GpG) towards platinum complexes. (1991) (5)
Improvement of Hepatocyte‐Specific Gene Expression by a Targeted Colchicine Prodrug (2003) (5)
Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution. (1998) (5)
Detection of beta-galactofuranosidase production by Penicillium and Aspergillus species using 4-nitrophenyl beta-D-galactofuranoside. (1989) (5)
Puromycin and some of its analogues: conformational properties in solution. A 360-MHz nuclear-magnetic-resonance investigation. (1977) (5)
Synthesis and biological evaluation of modified DNA fragments for the study of nucleotide excision repair in E. coli. (1999) (3)
A versatile approach towards regioselective platinated DNA sequences. (2003) (3)
SYNTHESIS OF PSEUDO-DISACCHARIDE ANALOGUES OF LIPID A: HAPTENS FOR THE GENERATION OF ANTIBODIES WITH GLYCOSIDASE ACTIVITY TOWARDS LIPID A (2002) (3)
Influence of 2-aminoadenosine, A', on the conformational behaviour of d(T-A'-T-A'). A one-dimensional proton NMR study at 300 MHz and 500 MHz. (1986) (3)
Biochemical and biophysical studies on the folding of the core region of the origin of replication of bacteriophage M13. (1990) (3)
2-5A-PNA complexes: a novel class of antisense compounds. (1999) (3)
Conformational consequences of the incorporation of arabinofuranosylcytidine in DNA. An NMR study of the DNA fragments d(CGCTAGCG) and d(CGaCTAGCG) in solution. (1989) (3)
Gene A protein interacting with recombinant plasmid DNAs containing 25-30 b.p. of the phi X174 replication origin. (1984) (2)
Conformational analysis of cyclophostin and designed analogs in comparison with the potent IP3 receptor agonist adenophostin A. (2001) (2)
The beta-glucuronyl-based prodrug strategy allows for its application on beta-glucuronyl-platinum conjugates. (2004) (2)
Conformational analysis of the 3'-5'-cyclic dinucleotide d less than pApA greater than by means of molecular mechanics. (1990) (2)
The duplex-hairpin conformational transition of d(CGCGCGATCGCGCG) and d(CGCGCGTACGCGCG): a thermodynamic and kinetic study. (1988) (2)
Automated sequence analysis of a synthetic DNA fragment by anion-exchange high-performance liquid chromatography. (1979) (2)
Solid-phase synthesis of H-Phe-Tyr-(pATAT)-NH2: a nucleopeptide fragment from the nucleoprotein of bacteriophage phi X174. (1990) (1)
Studies on DNA unwinding. Proton and phosphorus nuclear-magnetic-resonance studies of gene V protein from bacteriophage M13, interacting with d(pC-G-C-G). (1977) (1)
gamma-Endorphin and schizophrenia: amino acid composition of gamma-endorphin and nucleotide sequence of gamma-endorphin cDNA from pituitary glands of schizophrenic patients. (1986) (1)
Non-contiguous regions of Z-DNA in a DNA dodecamer. (1989) (1)
Conformational analysis of the tetranucleotides m6(2)A-m6(2)A-U-m6(2)A(m6(2)A = N6-dimethyladenosine) and U-m6(2)A-U-m6(2)A and of the hybrid dA-r(U-A). A one- and two-dimensional NMR study. (1988) (1)
Influence of N6-methylation of residue A(5) on the conformational behaviour of d(C-C-G-A-A-T-T-C-G-G) in solution studied by 1H-NMR spectroscopy. 1. The duplex form. (1987) (0)
Application of cyclic sulfates in the synthesis of 6-deoxy-D-manno-heptopyranose derivatives. (1992) (0)
Synthesis of phosphorothioate-containing DNA fragments by a modified hydroxybenzotriazole phosphotriester approach. (1984) (0)
Conformational analysis of furanoid epsilon-sugar amino acid containing cyclic peptides by NMR spectroscopy, molecular dynamics simulation, and X-ray crystallography: evidence for a novel turn structure. (2003) (0)
Conformational analysis of a ribopentanucleoside tetraphosphate in aqueous solution. A two-dimensional NMR study at 500 MHz. (1983) (0)
Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by omega,omega,omega-triphenylalcohols and UDP derivatives. (1992) (0)
Solid-phase synthesis of the nucleopeptide fragment H-Asp-Ser[pAAAGTAAGCC]-Glu-OH from the nucleoprotein of Bacillus subtilis phage phi 29. (1992) (0)
Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal beta-hexosaminidases. (2004) (0)
Sequence analysis of synthetic oligonucleotides by high-performance liquid anion-exchange chromatography. (1977) (0)
Molecular structure of d(m5CGTAm5CG): TA pairs in Z-DNA and the consequences. (1983) (0)
Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of m-6-2-A-C-C-U-C-C and A-C-C-U-C-m-4-2C via phosphotriester intermediates. (1977) (0)
Use of a Novel alpha-Hydroxyethylating Reagent in the Stereoselective Synthesis of Lincosamine. (1996) (0)
Conformational analysis of m4(2)C-m4(2)C-m6(2)A: a chemically modified 3'-acceptor end of tRNA, studied by NMR and CD methods. (1983) (0)
Chemical synthesis of an effective inhibitor of protein synthesis in eukaryotic cells: pppA2'-5'A2'-5'A and some analogues. (1980) (0)

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What Schools Are Affiliated With Jacobus Hubertus van Boom?

Jacobus Hubertus van Boom is affiliated with the following schools:

University of Amsterdam
Utrecht University
Leiden University