Jacques Dubochet
#2,093
Most Influential Person Now
Swiss chemist
Jacques Dubochet's AcademicInfluence.com Rankings
Jacques Dubochetchemistry Degrees
Chemistry
#232
World Rank
#478
Historical Rank
Physical Chemistry
#780
World Rank
#836
Historical Rank
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Chemistry
Jacques Dubochet's Degrees
- PhD Physical Chemistry University of Geneva
Why Is Jacques Dubochet Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jacques Dubochet is a retired Swiss biophysicist. He is a former researcher at the European Molecular Biology Laboratory in Heidelberg, Germany, and an honorary professor of biophysics at the University of Lausanne in Switzerland.
Jacques Dubochet's Published Works
Published Works
- Cryo-electron microscopy of vitrified specimens (1988) (2011)
- Cryo-electron microscopy of viruses (1984) (1138)
- Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization (2004) (650)
- Geometry and physics of knots (1996) (534)
- On the preparation of cryosections for immunocytochemistry. (1984) (448)
- Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State (2008) (427)
- Electron microscopy of frozen water and aqueous solutions (1982) (422)
- Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ (2008) (369)
- Cryo-Transmission Electron Microscopy of Frozen-Hydrated Sections of Escherichia coli and Pseudomonas aeruginosa (2003) (332)
- A new preparation method for dark-field electron microscopy of biomacromolecules. (1971) (326)
- Cryo‐electron microscopy of vitreous sections (2004) (286)
- Electron microscopy of frozen hydrated sections of vitreous ice and vitrified biological samples (1983) (254)
- Cutting artefacts and cutting process in vitreous sections for cryo-electron microscopy. (2005) (245)
- Cryo-electron microscopy of vitreous sections of native biological cells and tissues. (2004) (241)
- Electron microscopy of frozen-hydrated bacteria (1983) (233)
- The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo. (1994) (226)
- Electron microscopy of frozen biological suspensions (1983) (220)
- Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA. (1995) (211)
- The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes. (2005) (206)
- Multifunctional lipid/quantum dot hybrid nanocontainers for controlled targeting of live cells. (2006) (197)
- Envelope structure of Semliki Forest virus reconstructed from cryo-electron micrographs (1986) (193)
- Electrophoretic mobility of DNA knots (1996) (171)
- A study of the structure of the T-layer of Bacillus brevis. (1973) (169)
- Cryo-negative staining. (1998) (155)
- Organization of double‐stranded DNA in bacteriophages: a study by cryo‐electron microscopy of vitrified samples. (1987) (147)
- Chromatin conformation and salt-induced compaction: three-dimensional structural information from cryoelectron microscopy (1995) (147)
- Cryo‐electron microscopy of vitrified chromosomes in situ. (1986) (140)
- Direct visualization of supercoiled DNA molecules in solution. (1990) (139)
- Cryo‐EM—the first thirty years (2012) (124)
- Frozen aqueous suspensions (1982) (121)
- Beam damage to organic material is considerably reduced in cryo-electron microscopy. (1980) (121)
- The cell in absence of aggregation artifacts. (2001) (116)
- Luminal particles within cellular microtubules (2006) (112)
- Scaling behavior of random knots (2003) (109)
- Tightness of random knotting. (2000) (107)
- Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin. (2005) (107)
- The physics of rapid cooling and its implications for cryoimmobilization of cells. (2007) (105)
- Sedimentation and electrophoretic migration of DNA knots and catenanes. (1998) (104)
- Emerging techniques: Cryo-electron microscopy of vitrified biological specimens (1985) (100)
- Visualization of cell microtubules in their native state (2007) (91)
- Granular Layer in the Periplasmic Space of Gram-Positive Bacteria and Fine Structures of Enterococcus gallinarum and Streptococcus gordonii Septa Revealed by Cryo-Electron Microscopy of Vitreous Sections (2006) (88)
- Cryoelectron microscopy of vitrified sections: a new challenge for the analysis of functional nuclear architecture (2005) (86)
- The duck-globin messenger-ribonucleoprotein complex. Resistance to high ionic strength, particle gel electrophoresis, composition and visualisation by dark-field electron microscopy. (1973) (82)
- Nucleosome arcs and helices. (1978) (81)
- How to "read" a vitreous section. (2007) (81)
- X-ray diffraction and electron microscope studies on the structure of bacterial F pili. (1979) (80)
- The apical localization of transcribing RNA polymerases on supercoiled DNA prevents their rotation around the template. (1992) (79)
- An oscillating cryo‐knife reduces cutting‐induced deformation of vitreous ultrathin sections (2003) (77)
- Comparison of different methods for thin section EM analysis of Mycobacterium smegmatis (2010) (74)
- Structure of intracellular mature vaccinia virus observed by cryoelectron microscopy (1994) (73)
- Properties of ideal composite knots (1997) (72)
- Bilayers of nucleosome core particles. (2001) (70)
- Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution. (2009) (68)
- Cryo-negative staining reduces electron-beam sensitivity of vitrified biological particles. (2002) (68)
- Fine Structure of the Deinococcus radiodurans Nucleoid Revealed by Cryoelectron Microscopy of Vitreous Sections (2005) (66)
- Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. (2000) (61)
- DNA in human and stallion spermatozoa forms local hexagonal packing with twist and many defects. (2001) (61)
- Electron beam radiation damage to organic inclusions in vitreous, cubic, and hexagonal ice (1986) (60)
- Conversion of a transmembrane to a water-soluble protein complex by a single point mutation (2002) (59)
- Electron microscopic localization of the binding sites of Escherichia coli RNA polymerase in the early promoter region of T7 DNA. (1974) (59)
- Are the light-harvesting I complexes from Rhodospirillum rubrum arranged around the reaction centre in a square geometry? (1998) (57)
- Cryo-electron microscopy of vitrified insect flight muscle. (1984) (57)
- High-pressure freezing for cryoelectron microscopy. (1995) (56)
- Electron microscopy of the chromosomes of dinoflagellates in situ: confirmation of Bouligand's liquid crystal hypothesis (1986) (55)
- Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles (2009) (55)
- Glass-forming microemulsions: vitrification of simple liquids and electron microscope probing of droplet-packing modes (1984) (55)
- Evaporation during preparation of unsupported thin vitrified aqueous layers for cryo-electron microscopy. (1990) (55)
- Electron beam‐induced changes in vitreous sections of biological samples (1998) (54)
- Cryo‐electron microscopy of vitrified SV40 minichromosomes: the liquid drop model. (1986) (54)
- Carbon loss during irradiation of T4 bacteriophages and E. coli bacteria in electron microscopes. (1975) (54)
- Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy. (2002) (52)
- DNA at the entry-exit of the nucleosome observed by cryoelectron microscopy. (1995) (51)
- 3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy (2006) (49)
- High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy. (2005) (48)
- Localization of breakage points in knotted strings (2001) (47)
- Compression and crevasses in vitreous sections under different cutting conditions (2008) (47)
- Self-assembly of single and closely spaced nucleosome core particles (1980) (46)
- Geometry and physics of catenanes applied to the study of DNA replication. (1998) (45)
- Improved anticontaminator for cryo‐electron microscopy with a Philips EM 400 (1984) (42)
- Comparison of slam‐freezing and high‐pressure freezing effects on the DNA cholesteric liquid crystalline structure (1996) (41)
- Amorphous solid water produced by cryosectioning of crystalline ice at 113 K (2002) (39)
- Low temperature electron microscopy. (1981) (37)
- CRYO-ELECTRON MICROSCOPY OF VITRIFIED WATER (1984) (37)
- On the Development of Electron Cryo-Microscopy (Nobel Lecture). (2018) (37)
- Extracellular matrix binding mixed micelles for drug delivery applications. (2009) (36)
- Spatial visualization of DNA in solution. (1991) (35)
- A Reminiscence about Early Times of Vitreous Water in Electron Cryomicroscopy. (2016) (35)
- Structure of globin mRNA and mRNA-protein particles. Use of dark-field electron microscopy. (1973) (34)
- Thermodynamic and Kinetic Effects in the Aggregation Behavior of a Poly(ethylene glycol-b-propylene sulfide-b-ethylene glycol) ABA Triblock Copolymer (2005) (33)
- Some progress in the use of a scanning transmission electron microscope for the observation of biomacromolecules. (1976) (33)
- Head structure of bacteriophages T2 and T4. (1988) (32)
- Reduction of beam damage by cryoprotection at 4 K (1981) (32)
- Length and shape variants of the bacteriophage T4 head: mutations in the scaffolding core genes 68 and 22 (1988) (30)
- Opposite effect of counterions on the persistence length of nicked and non-nicked DNA. (1997) (29)
- Cryoelectron microscopy of DNA molecules in solution. (1992) (27)
- High resolution dark‐field electron microscopy (1973) (27)
- Knotted Fishing Line, Covalent Bonds, and Breaking Points (1999) (25)
- Brownian dynamics simulation of DNA condensation. (1999) (23)
- Freezing, fracturing, and etching artifacts in particulate suspensions. (1980) (23)
- Predicting Optimal Lengths of Random Knots (2000) (20)
- Sulphur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterisation and analysis (1996) (20)
- Electron‐beam‐induced amorphization of ice III or IX obtained by high‐pressure freezing (1996) (20)
- Electron microscopy of frozen hydrated specimens: preparation and characteristics. (1986) (19)
- Expression of chirality in columnar hexagonal phases or DNA and nucleosomes (2008) (19)
- Interactions between actin and myosin filaments in skeletal muscle visualized in frozen-hydrated thin sections. (1989) (18)
- Cryo- Electron Tomography and Fluorescence Microscopy of Unicellular Algae in Vitreous Cryosections (2005) (18)
- Switch-peptides: from conformational studies to Alzheimer's disease (2006) (18)
- Selective adsorption of particles to the supporting film and its consequences on particle counts in electron microscopy. (1972) (17)
- Study of the Deinococcus radiodurans Nucleoid by Cryoelectron Microscopy of Vitreous Sections: Supplementary Comments (2006) (17)
- IDEAL KNOTS AND THEIR RELATION TO THE PHYSICS OF REAL KNOTS (2008) (16)
- The Nobel Prize in Chemistry 2015. (2015) (16)
- Freezing: facts and hypothesis. (1991) (16)
- Amendment to: Electron beam damage to organic specimens at liquid helium temperature (1983) (15)
- Determination of the DNA helical repeat by cryo-electron microscopy (1994) (15)
- Teaching scientists to be citizens (2003) (13)
- Dark-field electron microscopic analysis of mitochondrial membranes. (1978) (12)
- Electron microscope observation of a fibre structure formed by non-specific binding of cAMP receptor protein to DNA. (1981) (12)
- CEMOVIS; cryo-electron microscopy of vitreous sections (2008) (11)
- Crystalline aggregation of a proteolytic fragment of the major head protein of bacteriophage T4. (1979) (10)
- Amorphous solid water produced by cryosectioning of crystalline ice at 113 K. (2002) (9)
- 3 D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy (2006) (9)
- The reaction centre of the photounit of Rhodospirillum rubrum is anchored to the light-harvesting complex with four-fold rotational disorder (1998) (9)
- The flying cylinder: a new algorithm for filament recognition in noisy stereo images. (1996) (8)
- Cryoultramicrotomy: Study of ice crystals and freezing damage (1984) (6)
- Rebuttal: Ring-Like Nucleoids and DNA Repair in Deinococcus radiodurans (2006) (6)
- High-resolution Study of DNA in Vitrified Sections (1990) (6)
- Cryo-Electron Microscopy of DNA (1994) (6)
- Ups and downs in early electron cryo-microscopy (2018) (6)
- Twisting in a crowd. (1993) (6)
- Genomics for citizens (2009) (5)
- Scaling of the average crossing number in equilateral random walks, knots and proteins (2005) (5)
- Cryo-electron microscopy of viruses in native state (1987) (5)
- DNA-DNA interaction in thin layer analysed by cryo-electron microscopy. (1995) (4)
- Citizen biologists (2008) (4)
- Cryopreservation of thin biological specimens for electron microscopy: Methods and applications (1990) (3)
- Reduction of Radiation Damage by Imaging with a Superconducting Lens System (1980) (3)
- Cryo-electron microscopy of vitreous sections of biological specimens (2003) (2)
- Making science in a fractal landscape. (2001) (2)
- Towards the direct determination of the shape of DNA molecules in solution. (1992) (2)
- Scientists - come out ! (2001) (1)
- Why is it so difficult to accept Darwin's theory of evolution? (2011) (1)
- New EMBO Member's Review Cryo-electron microscopy of vitreous sections (2004) (1)
- A simple method to measure resolution on micrographs (1976) (1)
- Corrigendum to “Cryo-electron microscopy of vitreous sections of native biological cells and tissues” [J. Struct. Biol. 148 (2004) 131–135] (2005) (1)
- Heartbeat Synchronized with Ventilation (0)
- Molecular architecture of the presynaptic compartment studied by cryo-electron tomography (2008) (0)
- Inter-filament interactions in muscle visualized in frozen-hydrated thin-sections (1988) (0)
- The Observation of Frozen Hydrated Sections by CTEM and STEM (1981) (0)
- Frozen-hydrated specimens for high-resolution electron-microscopy (1982) (0)
- Life, Liquids and Cryo-Electron Microscopy (1987) (0)
- Structure of supercoiled DNA changes with increasing counterions concentrations - cryoelectron microscopy studies and Monte-Carlo simulations (1994) (0)
- Medicine for today and tomorrow (2001) (0)
- Evaluation of beam damage in catalase crystals observed in vitrified sections (2008) (0)
- DNA helical repeats (1989) (0)
- Organization ofdouble-stranded DNA inbacteriophages: a study bycryo-electron microscopy ofvitrified samples (1987) (0)
- Electron Microscopy (2021) (0)
- Electron microscopy at 4K (1982) (0)
- Microphases of spermidine‐condensed DNA. Structural analysis by cryoelectron microscopy (1995) (0)
- Vitreous sections of cells and suspensions (2000) (0)
- Three-dimensional reconstruction of DNA molecules (1995) (0)
- ErrataSelf-Assembly of |gb-Amyloid 42 Is Retarded by Small Molecular Ligands at the Stage of Structural Intermediates: Volume 130, Numbers 2/3 (2000), pages 232–246 (2001) (0)
- ARC-LIKE AND HELICAL ARRANGEMENTS OF NUCLEOSOME CORES (1979) (0)
- Artefacts of classical preparation methods for transmission electon microscopy followed step by step using cryoelectron microscopy (1995) (0)
- Seeing DNA in action (1992) (0)
- DETERMINATION OF THE DNA HELICAL REPEAT AND OF THE STRUCTURE OF SUPERCOILED DNA BY CRYO-ELECTRON MICROSCOPY (1996) (0)
- 3D reconstruction of DNA molécules (1995) (0)
- Obituary: Eduard Kellenberger (1920–2004) (2005) (0)
- Cryo-electron microscopy of vitreous sections: Cell ultrastructure revisited (2002) (0)
- Light and electron microscopy of phagosomes (2008) (0)
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