James A. Joseph
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James A. Josephbiology Degrees
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Biochemistry
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Chemistry Biology
James A. Joseph's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry Stanford University
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(Suggest an Edit or Addition)James A. Joseph's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. (1999) (2180)
- Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation (1999) (994)
- Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory (2005) (522)
- Essential fatty acids and the brain: possible health implications (2000) (499)
- Blueberry supplementation improves memory in older adults. (2010) (484)
- A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects. (2001) (431)
- Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits (1998) (430)
- Blueberry Supplementation Enhances Signaling and Prevents Behavioral Deficits in an Alzheimer Disease Model (2003) (368)
- Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans (2006) (357)
- Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds. (2005) (332)
- Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system. (2004) (323)
- Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats (2000) (317)
- Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults ( small star, filled). (2002) (317)
- Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. (2000) (306)
- Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. (2010) (302)
- Modulation of Hippocampal Plasticity and Cognitive Behavior by Short-term Blueberry Supplementation in Aged Rats (2004) (283)
- Neurobehavioral aspects of antioxidants in aging (2000) (242)
- The beneficial effects of fruit polyphenols on brain aging (2005) (240)
- Nutrition, Brain Aging, and Neurodegeneration (2009) (240)
- Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide‐activated BV2 microglia (2007) (216)
- Berry fruit supplementation and the aging brain. (2008) (216)
- Blueberry Supplemented Diet: Effects on Object Recognition Memory and Nuclear Factor-kappa B Levels in Aged Rats (2004) (214)
- Age-related changes in the nigrostriatum: a behavioral and biochemical analysis. (1978) (200)
- Grape juice, berries, and walnuts affect brain aging and behavior. (2009) (197)
- Effects of Concord grape juice on cognitive and motor deficits in aging. (2006) (195)
- Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease (2012) (191)
- Polyphenolics enhance red blood cell resistance to oxidative stress: in vitro and in vivo. (2000) (184)
- Fruit Polyphenolics and Brain Aging (2002) (184)
- Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brain (2002) (176)
- Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging (2007) (169)
- Psychomotor and spatial memory performance in aging male Fischer 344 rats (1998) (167)
- BHT blocks NF-κB activation and ethanol-induced brain damage (2006) (167)
- Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging (1995) (158)
- Effects of blackberries on motor and cognitive function in aged rats (2009) (157)
- Spatial Learning and Memory Deficits Induced by Exposure to Iron-56-Particle Radiation (2000) (156)
- Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin. (1996) (151)
- Short-Term Dietary Supplementation of Blueberry Polyphenolics: Beneficial Effects on Aging Brain Performance and Peripheral Tissue Function (2000) (147)
- Dietary restriction retards the age-associated loss of rat striatal dopaminergic receptors. (1981) (145)
- Psychomotor performance in the senescent rodent: reduction of deficits via striatal dopamine receptor up-regulation (1983) (145)
- Possible "accelerated striatal aging" induced by 56Fe heavy-particle irradiation: implications for manned space flights. (1992) (139)
- Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging. (2008) (134)
- Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus (2008) (128)
- Oxidative Stress and Inflammation in Brain Aging: Nutritional Considerations (2005) (127)
- A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats (2008) (125)
- Effect of age on the radial arm water maze—a test of spatial learning and memory (2004) (123)
- Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits. (2002) (121)
- Effect of L-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats. (1997) (119)
- Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection (2006) (113)
- Fruit Polyphenols and Their Effects on Neuronal Signaling and Behavior in Senescence (2007) (113)
- Delayed loss of striatal dopamine receptors during aging of dietarily restricted rats (1984) (111)
- Modulation of cognition and behavior in aged animals: role for antioxidant- and essential fatty acid-rich plant foods. (2009) (109)
- Effect of age on sensitivity to pain and brain opiate receptors (1981) (106)
- Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention (2000) (105)
- Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial (2018) (104)
- Effect of aging on striatal dopamine receptor subtypes in Wistar rats (1986) (102)
- BHT blocks NF-kappaB activation and ethanol-induced brain damage. (2006) (97)
- Dose-dependent effects of walnuts on motor and cognitive function in aged rats (2008) (95)
- Effects of aging on cerebellar noradrenergic function and motor learning: nutritional interventions (1999) (91)
- Recent advances in berry supplementation and age-related cognitive decline (2009) (89)
- Cellular and Molecular Mechanisms of Impaired Dopaminergic Function during Aging (1994) (89)
- Nutritional Intervention in Brain Aging (2007) (89)
- Brain Signaling and Behavioral Responses Induced by Exposure to 56Fe-Particle Radiation (2002) (88)
- A Blueberry-Enriched Diet Attenuates Nephropathy in a Rat Model of Hypertension via Reduction in Oxidative Stress (2011) (87)
- The state versus amyloid-β: the trial of the most wanted criminal in Alzheimer disease (2002) (85)
- Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells. (2000) (85)
- Age-related neurodegeneration and oxidative stress: putative nutritional intervention. (1998) (84)
- Conformational changes in muscarinic receptors may produce diminished cholinergic neurotransmission and memory deficits in aged rats (1985) (83)
- Effects of fruits and vegetables on levels of vitamins E and C in the brain and their association with cognitive performance. (2002) (82)
- The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. (2015) (81)
- Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. (2002) (81)
- Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress (2005) (80)
- Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence (1988) (79)
- Cognitive deficits induced by 56Fe radiation exposure. (2003) (78)
- Structure-activity relationships of quercetin in antagonizing hydrogen peroxide-induced calcium dysregulation in PC12 cells. (1999) (74)
- Age differences in sensitivity to H2O2- or NO-induced reductions in K(+)-evoked dopamine release from superfused striatal slices: reversals by PBN or Trolox. (1996) (74)
- Loss of D2 receptors during aging is partially due to decreased levels of mRNA (1991) (74)
- Blueberry-Enriched Diet Protects Rat Heart from Ischemic Damage (2009) (72)
- Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. (2011) (69)
- Effects of exposure to heavy particles on a behavior mediated by the dopaminergic system. (2000) (68)
- Central determinants of age-related declines in motor function. (1988) (68)
- Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-κB activation (2009) (67)
- Membrane and Receptor Modifications of Oxidative Stress Vulnerability in Aging: Nutritional Considerations (1998) (66)
- Effect of vitamin E intake on levels of vitamins E and C in the central nervous system and peripheral tissues: implications for health recommendations (1999) (65)
- Alterations in muscarinic control of striatal dopamine autoreceptors in senescence: a deficit at the ligand-muscarinic receptor interface? (1988) (65)
- Roles of vitamins E and C on neurodegenerative diseases and cognitive performance. (2002) (64)
- Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat. (1981) (63)
- Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata (1990) (63)
- Effects of exposure to different types of radiation on behaviors mediated by peripheral or central systems. (1998) (63)
- Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic rays (2005) (62)
- Deficits in the sensitivity of striatal muscarinic receptors induced by 56Fe heavy-particle irradiation: further "age-radiation" parallels. (1993) (62)
- Walnut Extract Inhibits LPS-induced Activation of Bv-2 Microglia via Internalization of TLR4: Possible Involvement of Phospholipase D2 (2010) (62)
- CNS-induced deficits of heavy particle irradiation in space: the aging connection. (2000) (61)
- Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress. (2007) (60)
- The putative role of free radicals in the loss of neuronal functioning in senescence (1992) (59)
- Differential protection among fractionated blueberry polyphenolic families against DA-, Abeta(42)- and LPS-induced decrements in Ca(2+) buffering in primary hippocampal cells. (2010) (59)
- Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats. (2009) (56)
- An assessment of the behavioral toxicity of high-energy iron particles compared to other qualities of radiation. (1989) (55)
- Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. (2010) (54)
- Role of membrane lipids in regulation of vulnerability to oxidative stress in PC12 cells: implication for aging. (2001) (53)
- Perspectives on the Amyloid-β Cascade Hypothesis (2004) (53)
- Effects of exposure to 56Fe particles or protons on fixed-ratio operant responding in rats. (2002) (52)
- CNS effects of heavy particle irradiation in space: behavioral implications. (1998) (52)
- The effects of dietary antioxidants on psychomotor performance in aged mice (1999) (52)
- Decrement of muscarinic receptor-stimulated low-K M GTPase in striatum and hippocampus from the aged rat (1992) (51)
- Chronic nimodipine treatment in aged rats: Analysis of motor and cognitive effects and muscarinic-induced striatal dopamine release (1994) (51)
- Hippocampal neurogenesis and PSA-NCAM expression following exposure to 56Fe particles mimics that seen during aging in rats (2005) (51)
- Predicting the failure of amyloid-β vaccine (2002) (50)
- Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain (2009) (50)
- Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging (2013) (49)
- Spatial learning and memory deficits induced by dopamine administration with decreased glutathione. (1998) (49)
- Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function. (2004) (49)
- Hyperoxia-induced changes in antioxidant capacity and the effect of dietary antioxidants. (1999) (49)
- Relative effectiveness of different particles and energies in disrupting behavioral performance (2007) (49)
- A Longitudinal Study of Operant Responding in RatsIrradiated when 2 Months Old (2005) (48)
- Effect of fruits, vegetables, or vitamin E--rich diet on vitamins E and C distribution in peripheral and brain tissues: implications for brain function. (2000) (48)
- Aging-related changes in rat striatal D2 receptor mRNA-containing neurons: a quantitative nonradioactive in situ hybridization study (1995) (47)
- Stimulatory effect of vitamin C on autophagy in glial cells (2002) (47)
- Diet as a factor in behavioral radiation protection following exposure to heavy particles. (2005) (47)
- Effect of age on object exploration, habituation, and response to spatial and nonspatial change. (2001) (46)
- Fruit extracts antagonize Abeta- or DA-induced deficits in Ca2+ flux in M1-transfected COS-7 cells. (2004) (46)
- The effects of proton exposure on neurochemistry and behavior. (2004) (46)
- Dopamine neurotoxicity: age-dependent behavioral and histological effects (2003) (46)
- Beneficial effects of berry fruit polyphenols on neuronal and behavioral aging (2006) (46)
- The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells (2013) (46)
- Amyloid-β: a (life) preserver for the brain (2002) (45)
- Life-long dietary restriction affects striatally-mediated behavioral responses in aged rats (1983) (44)
- In vivo assessment of striatal dopamine release in the aged male fischer 344 rat (1995) (43)
- Upregulation of Striatal Dopamine Receptors and Improvement of Motor Performance in Senescence (1988) (42)
- Oxidant Injury in PC12 Cells—A Possible Model of Calcium “Dysregulation” in Aging: I. Selectivity of Protection Against Oxidative Stress (1997) (41)
- Oxidative stress and age-related neuronal deficits (1996) (40)
- Cholesterol: a two-edged sword in brain aging. (1997) (40)
- Behavioral and neurochemical abnormalities after exposure to low doses of high-energy iron particles. (1989) (40)
- Qualitative versus quantitative caloric intake: are they equivalent paths to successful aging? (2002) (40)
- Relationship between linear energy transfer and behavioral toxicity in rats following exposure to protons and heavy particles. (1991) (39)
- Neostriatal dopamine receptor loss and behavioral deficits in the senescent rat. (1981) (39)
- Decreased striatal D2 dopamine receptor mRNA synthesis during aging. (1993) (39)
- Effect of aging on striatal dopamine receptor subtype recovery following N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline blockade and relation to motor function in Wistar rats (1987) (38)
- Effects of heavy particle irradiation and diet on object recognition memory in rats (2009) (38)
- Attenuation of baroreflexes during operant cardiac conditioning. (1982) (37)
- Age-related changes in neutral sphingomyelin-specific phospholipase C activity in striatum, hippocampus, and frontal cortex: Implication for sensitivity to stress and inflammation (2005) (37)
- Muscarinic acetylcholine receptor subtype mRNA expression and ligand binding in the aged rat forebrain (1991) (37)
- Behavioral endpoints for radiation injury. (1994) (37)
- Serial Review: Flavonoids and Isoflavones (Phytoestrogens: Absorption, Metabolism, and Bioactivity) Serial Review Editor: Catherine Rice-Evans FLAVONOIDS AND THE BRAIN: INTERACTIONS AT THE BLOOD-BRAIN BARRIER AND THEIR PHYSIOLOGICAL EFFECTS ON THE CENTRAL NERVOUS SYSTEM (2004) (36)
- Effect of aging on prolactin regulation of rat striatal dopamine receptor concentrations. (1983) (36)
- The striatal dopaminergic system as a model for modulation of altered neurotransmitter action during aging: effects of dietary and neuroendocrine manipulations. (1986) (35)
- [3H]Dopamine accumulation and release from striatal slices in young, mature and senescent rats (1981) (35)
- The effects of heavy particle irradiation on exploration and response to environmental change. (2004) (34)
- Area specific alterations in muscarinic stimulated low K m GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction (1994) (34)
- Automated measurement of age-related changes in the locomotor response to environmental novelty and home-cage activity (2001) (34)
- Reduction of motor behavioural deficits in senescence via chronic prolactin or estrogen administration: time course and putative mechanisms of action (1989) (34)
- Antioxidant and pro-oxidant capacity of catecholamines and related compounds. Effects of hydrogen peroxide on glutathione and sphingomyelinase activity in pheochromocytoma PC12 cells: potential relevance to age-related diseases (2001) (33)
- Blueberry extract alters oxidative stress-mediated signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes. (2006) (33)
- Changes in G Protein‐mediated Signal Transduction in Aging and Alzheimer's Disease (1993) (32)
- Reductions of 56Fe heavy-particle irradiation-induced deficits in striatal muscarinic receptor sensitivity by selective cross-activation/inhibition of second-messenger systems. (1994) (31)
- Survival and Cardioprotective Benefits of Long-Term Blueberry Enriched Diet in Dilated Cardiomyopathy Following Myocardial Infarction in Rats (2009) (31)
- In vivo or in vitro administration of the nitrone spin-trapping compound, n-tert-butyl-α-phenylnitrone, (PBN) reduces age-related deficits in striatal muscarinic receptor sensitivity (1995) (31)
- Muscarinic receptor subtype determines vulnerability to oxidative stress in COS-7 cells. (2002) (30)
- Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particle. (2003) (30)
- The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium "dysregulation" in PC12 cells. (1999) (30)
- Effects of heavy particle irradiation and diet on amphetamine- and lithium chloride-induced taste avoidance learning in rats (2002) (30)
- The effects of aging on muscarinic receptor/G-protein coupling in the rat hippocampus and striatum (1992) (30)
- Dietary supplementation with blueberry extract improves survival of transplanted dopamine neurons (2006) (29)
- Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory (2007) (28)
- Oxidant Injury in PC12 Cells—A Possible Model of Calcium “Dysregulation” in Aging: II. Interactions with Membrane Lipids (1997) (27)
- Instrumental control of cardioacceleration induced by central electrical stimulation. (1981) (27)
- Dissociation of Striatal GTPase and Dopamine Release Responses to Muscarinic Cholinergic Agonists in F344 Rats: Influence of Age and Dietary Manipulation (1995) (26)
- Changes in gene expression in the rat hippocampus following exposure to 56Fe particles and protection by berry diets. (2013) (25)
- Age-related decrease in apomorphine modulation of acetylcholine release from rat striatal slices (1984) (25)
- Psychomotor effects of dopamine infusion under decreased glutathione conditions. (1997) (25)
- Age-specific alterations in muscarinic stimulation of K+-evoked dopamine release from striatal slices by cholesterol andS-adenosyl-l-methionine (1995) (24)
- Dopamine and Abeta-induced stress signaling and decrements in Ca2+ buffering in primary neonatal hippocampal cells are antagonized by blueberry extract. (2007) (24)
- Predicting the failure of amyloid-beta vaccine. (2002) (24)
- Reduction of 3-methoxytyramine concentrations in the caudate nucleus of rats after exposure to high-energy iron particles: evidence for deficits in dopaminergic neurons. (1990) (24)
- Alzheimer's, ageing and amyloid: an absurd allegory? (1997) (23)
- Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles (2007) (23)
- Effect of normobaric hyperoxia on two indexes of synaptic function in Fisher 344 rats. (1999) (23)
- Receptor- and age-selective effects of dopamine oxidation on receptor-G protein interactions in the striatum. (1998) (23)
- Muscarinic receptor concentrations and dopamine release in aged rat striata (1992) (23)
- Uncoupling of muscarinic cholinergic phosphoinositide signals in senescent cerebral cortical and hippocampal membranes (1998) (23)
- Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays (2012) (22)
- Selective susceptibility of cultured striatal neurons to kainic acid (1992) (22)
- Iron-56 Irradiation Diminishes Muscarinic but Not α 1 -Adrenergic-Stimulated Low-K m GTPase in Rat Brain (1994) (22)
- Desensitization of muscarinic acetylcholine receptors: possible relation to receptor heterogeneity and phosphoinositides (1986) (22)
- Age-Related Neostriatal Alterations in the Rat: Failure of L-DOPA to Alter Behavior (1980) (21)
- Reduction of motor behavioral deficits in senescent animals via chronic prolactin administration II. Non-stereotypic behaviors (1986) (21)
- Nutritional Interventions in Aging and Age‐Associated Diseases (2007) (21)
- Altered Striatal Dopaminergic and Cholinergic Reciprocal Inhibitory Control and Motor Behavioral Decrements in Senescence (1988) (21)
- What is aging? What is its role in Alzheimer's disease? What can we do about it? (2005) (21)
- Sensitivity to psychoactive drugs and the serotonergic neuronal system. (1977) (21)
- 7 Hormonal Regulation of Motor Behavior in Senescence (1993) (20)
- Effects of exposure to 56Fe particles on the acquisition of a conditioned place preference in rats. (2001) (20)
- Muscarinic receptor subtype determines vulnerability to amyloid beta toxicity in transfected cos-7 cells. (2003) (20)
- Age-related loss of cholinergic-muscarinic coupling to PLC: Comparison with changes in brain regional PLC subtypes mRNA distribution (1996) (19)
- Effect of diet on the disruption of operant responding at different ages following exposure to 56Fe particles (2005) (19)
- Behavioral sensitivity to LSD: Dependency upon the pattern of central 5HT depletion (1977) (18)
- Nerve growth factor affects the cholinergic neurochemistry and behavior of aged rats. (1993) (18)
- Age-related impairment in striatal muscarinic cholinergic signal transduction is associated with reduced membrane bilayer width measured by small angle X-ray diffraction. (1995) (18)
- Differential effect of dopamine catabolism and uptake inhibition on dopamine-induced calcium dysregulation and viability loss. (1999) (18)
- Emesis in ferrets following exposure to different types of radiation: a dose-response study. (1992) (17)
- Magnesium activation of GTP hydrolysis or incubation in S-adenosyl-l-methionine reverses iron-56-particle-induced decrements in oxotremorine enhancement of K+-evoked striatal release of dopamine. (1999) (16)
- Age-related changes in transcriptional and posttranscriptional regulation of the dopaminergic system. (1994) (16)
- The deleterious effects of aging and kainic acid may be selective for similar striatal neuronal populations (1991) (16)
- Peculiarities of the effect of hormones and transmitters during aging: modulation of changes in dopaminergic action. (1988) (16)
- Cytoprotective effects of anthocyanins and other phenolic fractions of Boysenberry and blackcurrant on dopamine and amyloid β-induced oxidative stress in transfected COS-7 cells † (2007) (15)
- Perspectives on the amyloid-beta cascade hypothesis. (2004) (15)
- Reduction of motor behavioral deficits in senescent animals via chronic prolactin administration I. Rotational behavior (1986) (15)
- The nitrone spin trap PBN alters the cellular response to H(2)O(2): activation of the EGF receptor/ERK pathway. (2002) (14)
- The M3 muscarinic receptor i3 domain confers oxidative stress protection on calcium regulation in transfected COS‐7 cells (2004) (13)
- The effects of antioxidants in the senescent auditory cortex (2006) (13)
- Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide (2007) (13)
- Amyloid-beta: a (life) preserver for the brain. (2002) (12)
- Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. (2010) (12)
- Radiation-induced increases in sensitivity of cataleptic behavior to haloperidol: Possible involvement of prostaglandins (1988) (12)
- Novel growth factor Gas6, phosphatidylserine and their age-related changes in the rat brain (2000) (12)
- Exposure to heavy charged particles affects thermoregulation in rats. (1994) (11)
- Blueberry treatment antagonizes C-2 ceramide-induced stress signaling in muscarinic receptor-transfected COS-7 cells. (2010) (10)
- Ill‐fated amyloid‐β vaccine (2002) (10)
- Comparison of the level of mRNA encoding m1 and m2 muscarinic receptors in brains of young and aged rats (1992) (9)
- Amphetamine-induced taste aversion learning in young and old F-344 rats following exposure to 56Fe particles (2007) (9)
- A reduced calorie-high fiber diet retards age-associated decreases in muscarinic receptor sensitivity (1995) (8)
- Open peer commentary Copernicus revisited: amyloid beta in Alzheimer's disease (2001) (8)
- Interaction between age and exposure to 56Fe particles on behavior and neurochemistry (2006) (7)
- Alterations in the behavioral effects of LSD by motivational and neurohumoral variables (1976) (7)
- Dopamine-induced stress signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes is partially mediated via the i3 loop and antagonized by blueberry extract. (2006) (7)
- Impaired Down-Regulation of Pituitary Dopamine Receptors by Estradiol in Aged Rats (1989) (7)
- Dietary modulation of the effects of exposure to 56Fe particles (2007) (7)
- Effects of Iron Particles on Behavior and Brain Function: Initial Studies (1988) (7)
- α 1-Adrenergic stimulation of low K m GTPase in rat striata is diminished with age (1992) (7)
- Age-Related Neuronal and Behavioral Deficits are Improved by Polyphenol-Rich Blueberry Supplementation (2005) (6)
- 4.3 Coupling of Neuronal Function to Oxygen and Glucose Metabolism Through Changes in Neurotransmitter Dynamics as Revealed with Aging, Hypoglycemia, and Hypoxia (2007) (6)
- Effect of a blueberry nutritional supplement on macronutrients, food group intake, and plasma vitamin E and vitamin C in US athletes (2008) (6)
- Iron-56 irradiation diminishes muscarinic but not alpha 1-adrenergic-stimulated low-Km GTPase in rat brain. (1994) (5)
- CHOLINERGIC SYSTEMS IN AGING: THE ROLE OF OXIDATIVE STRESS (1992) (5)
- Dangers of the amyloid-β vaccination (2002) (5)
- Effect of aging on vulnerability of striatal D1 And D2 dopamine receptor-containing neurons to kainic acid (1997) (5)
- Loss of muscarinic regulation of striatal dopamine function in senescence (1992) (4)
- Hormonal regulation of motor behavior in senescence. (1993) (4)
- Blueberry antagonism of C-2 ceramide disruption of Ca2+ responses and recovery in MAChR-transfected COS-7 cell. (2008) (4)
- Somatomotor related hippocampal rhythmic slow activity in the monkey (Macaca mulatta) (1981) (3)
- Responses of circulating urea cycle and branched-chain amino acids to feeding in adult and aged Fischer-344 rats (1997) (3)
- Mobility and cognition: End points for dietary interventions in aging (2014) (3)
- Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging (2013) (2)
- Membrane Constituencies and Receptor Subtype Contribute to Age-Related Increases in Vulnerability to Oxidative Stress (1998) (2)
- Neurological Aging and Nutritional Intervention (2002) (2)
- Phytocemicals in Foods and Beverages: Effects on the Central Nervous System (2005) (2)
- Dietary and Neuroendocrine Modulation of Age Related Changes in Dopaminergic Action During Aging (1987) (2)
- Changes in hippocampal rhythmic slow activity during instrumental cardiovascular conditioning in the monkey (Macaca mulatta) (1982) (2)
- Striatally-mediated response of some structurally rigid analogues of dopamine (1986) (2)
- An Evaluation of the Relative Behavioral Toxicity of Heavy Particles (1993) (2)
- Ill-fated amyloid-beta vaccine. (2002) (2)
- Oxidative Stress and the Loss of Muscarinic and Dopaminergic Responsiveness in Senescence (1992) (2)
- Dangers of the amyloid-beta vaccination. (2002) (1)
- Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits (2009) (1)
- Neuronal Environment and Age-Related Neurodegenerative Disease: Nutritional Modification (2001) (1)
- Effects of berry fruits on neurocognitive deficits produced by exposure to space radiation. (2008) (1)
- Alterations in Muscarinic Cholinergic Neurotransmission in Normal Aging and Alzheimer's Disease: Implications for Current Therapeutic Strategies for Treatment of Dementia (1993) (1)
- Justice and Reverse Discrimination. By Alan H. Goldman. Princeton, Princeton University Press, 1979. 251 pp. $16.50 (1980) (1)
- Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease (2013) (1)
- IVth Serling Symposium on the biology of aging: A summary (1993) (1)
- Oxidative Stress and the Loss of Receptor Sensitivity in Aging (1995) (1)
- Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays (2011) (1)
- Twenty-sixth annual meeting — American Aging Association Eleventh annual meeting — American College of Clinical Gerontology (2006) (1)
- Oxidative Stress and Reduced Receptor Responsiveness in Senescence (1994) (1)
- Berry Fruit and Nuts: Their Role in Reducing Oxidative Stress and Inflammation in the Aging Brain (2012) (0)
- Beneficial effects of fruit extracts on neuronal function and behavior following 56Fe irradiation (2006) (0)
- Correlation of Cholinergic Functional Stimulation by Exogenous NGF with Aged Rat Behavior (1991) (0)
- EFFECTS OF EXPOSUREZ TO HEAVY PARTICLES ON A BEHAVIOR ~DIATED BY THE DOPAM~NERGIC SYSTEM (2003) (0)
- Special Report from the Challenging Views of Alzheimer ’ s Disease What is aging ? What is its role in Alzheimer ’ s disease ? What can we do about it ? (2005) (0)
- Introduction: Nutritional modulation of aging. (2005) (0)
- Age/Radiation Parallels in the Effects of 56Fe Particle Irradiation and Protection by Berry Diets (2008) (0)
- Symposium S4: Aging‐Associated Cognitive Dysfunction: Coping with Perturbations to Homeostasis (2004) (0)
- Preface (2000) (0)
- Nutritional Antioxidants, Vitamins, Cognition, and Neurodegenerative Disease (2004) (0)
- Mitigation of oxidative stress and inflammatory signaling by fruit and walnut polyphenols: implications for cognitive aging. (2010) (0)
- Reply (1995) (0)
- Oxidative Adaptation in Aging and Alzheimer’s Disease: The Roles of Amyloid and Tau (2005) (0)
- MODULATION OF BARORECEPTOR SENSITIVITY DURING OPERANT CARDIAC CONDITIONING (1981) (0)
- Dietary and Aging Influences on Neuronal Function (2003) (0)
- The Effects of Daily Dietary Blueberry Supplementation on Vitamin E and C Intake and Serum Levels (2004) (0)
- Some Behavioral Effects of Exposure to Low Doses of Fe-56 Particles (1999) (0)
- Method for improving oxidative stress and working memory by administering pterostilbene (2008) (0)
- Exposure to Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory (2007) (0)
- “Brainberries” and Aging (2008) (0)
- Caloric Restriction Versus a Diet High in Antioxidants: Are they Equipotent in Altering or Reversing the Course of Aging? (2002) (0)
- Morpho-Physiological and Behavioral Relationships in Senescence. (1982) (0)
- The Beneficial Effects of Fruit and Vegetable Supplementation on Neuronal Signaling and Behavior in Aging (2006) (0)
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What Schools Are Affiliated With James A. Joseph?
James A. Joseph is affiliated with the following schools:
