James C. Eisenach | Academic Influence

Why Is James C. Eisenach Influential?

According to Wikipedia, James C. Eisenach is an American anesthesiologist, currently the FM James, III Professor at Wake Forest School of Medicine, Wake Forest University and the former Editor-in-Chief of American Society of Anesthesiologists's journal Anesthesiology.

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James C. Eisenach's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Alpha sub 2 -Adrenergic Agonists for Regional Anesthesia: A Clinical Review of Clonidine (1984 - 1995) (1996) (915)
Epidural clonidine analgesia for intractable cancer pain (1995) (494)
Severity of acute pain after childbirth, but not type of delivery, predicts persistent pain and postpartum depression (2008) (487)
Animal models and the prediction of efficacy in clinical trials of analgesic drugs: A critical appraisal and call for uniform reporting standards (2008) (275)
Phase I Safety Assessment of Intrathecal Neostigmine Methylsulfate in Humans (1995) (274)
Epidural Clonidine Treatment for Refractory Reflex Sympathetic Dystrophy (1993) (241)
Multifactorial Preoperative Predictors for Postcesarean Section Pain and Analgesic Requirement (2006) (240)
Hemodynamic and Analgesic Actions of Epidurally Administered Clonidine (1993) (236)
Patient-controlled analgesia following cesarean section: a comparison with epidural and intramuscular narcotics. (1988) (235)
Polyanalgesic Consensus Conference 2007: Recommendations for the Management of Pain by Intrathecal (Intraspinal) Drug Delivery: Report of an Interdisciplinary Expert Panel (2007) (228)
Epidural clonidine analgesia following surgery: phase I. (1989) (215)
Polyanalgesic Consensus Conference 2003: an update on the management of pain by intraspinal drug delivery-- report of an expert panel. (2004) (210)
Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. (1999) (202)
Epidural clonidine analgesia for intractable cancer pain: phase I. (1989) (189)
Intrathecal Amitriptyline Acts as an N‐Methyl‐D‐Aspartate Receptor Antagonist in the Presence of Inflammatory Hyperalgesia in Rats (1995) (179)
Intravenous Remifentanil Produces Withdrawal Hyperalgesia in Volunteers with Capsaicin-Induced Hyperalgesia (2003) (179)
Intrathecal Sufentanil Compared to Epidural Bupivacaine for Labor Analgesia (1994) (161)
Studies of the composition of purified Torpedo californica acetylcholine receptor and of its subunits. (1979) (154)
Gabapentin Activates Spinal Noradrenergic Activity in Rats and Humans and Reduces Hypersensitivity after Surgery (2007) (154)
Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain (2008) (144)
Pharmacology of opioid and nonopioid analgesics in chronic pain states. (2001) (141)
Studies on the Safety of Chronically Administered Intrathecal Neostigmine Methylsulfate in Rats and Dogs (1995) (138)
Muscarinic-mediated analgesia. (1999) (135)
Morphological and pharmacological evidence for the role of peripheral prostaglandins in the pathogenesis of neuropathic pain (2002) (135)
Interaction between Intrathecal Neostigmine and Epidural Clonidine in Human Volunteers (1996) (129)
Epidural Clonidine Produces Antinociception, But Not Hypotension, In Sheep (1987) (129)
Intrathecal clonidine alleviates allodynia in neuropathic rats: interaction with spinal muscarinic and nicotinic receptors. (1998) (128)
Spinal glial activation contributes to postoperative mechanical hypersensitivity in the rat. (2006) (125)
Effects of Laparotomy on Spontaneous Exploratory Activity and Conditioned Operant Responding in the Rat: A Model for Postoperative Pain (2004) (125)
Postoperative Analgesia from Intrathecal Neostigmine in Sheep (1995) (124)
Analgesia from a peripherally active κ-opioid receptor agonist in patients with chronic pancreatitis (2003) (123)
A cholinergic interaction in alpha 2 adrenoceptor-mediated antinociception in sheep. (1993) (123)
Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain (2003) (121)
Epidural clonidine analgesia after cesarean section. (1990) (121)
Intrathecal, but Not Intravenous, Clonidine Reduces Experimental Thermal or Capsaicin-Induced Pain and Hyperalgesia in Normal Volunteers (1998) (121)
Intrathecal neostigmine for post-cesarean section analgesia: dose response. (1997) (121)
Resolution of Pain after Childbirth (2013) (119)
Role of protons in activation of cardiac sympathetic C‐fibre afferents during ischaemia in cats (1999) (119)
0.125% Ropivacaine Is Similar to 0.125% Bupivacaine for Labor Analgesia Using Patient-Controlled Epidural Infusion (1998) (117)
Spinal Cannabinoid Receptor Type 2 Activation Reduces Hypersensitivity and Spinal Cord Glial Activation after Paw Incision (2007) (117)
Pharmacokinetics and Pharmacodynamics of Intraspinal Dexmedetomidine in Sheep (1994) (116)
Perioperative administration of the α2-adrenoceptor agonist clonidine at the site of nerve injury reduces the development of mechanical hypersensitivity and modulates local cytokine expression (2003) (114)
Intravenous Opioids Stimulate Norepinephrine and Acetylcholine Release in Spinal Cord Dorsal Horn: Systematic Studies in Sheep and an Observation in a Human (1996) (112)
Epidural clonidine analgesia for intractable cancer pain. The Epidural Clonidine Study Group. (1995) (109)
alpha2A-adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes. (2001) (108)
Pharmacokinetics and dynamics of intravenous, intrathecal, and epidural clonidine in sheep. (1989) (108)
Medium and large injured dorsal root ganglion cells increase TRPV-1, accompanied by increased α2C-adrenoceptor co-expression and functional inhibition by clonidine (2005) (107)
Intrathecal α2‐Adrenergic Agonists Stimulate Acetylcholine and Norepinephrine Release from the Spinal Cord Dorsal Horn in Sheep: An In Vivo Microdialysis Study (1997) (103)
Opioid Self-administration in the Nerve-injured Rat: Relevance of Antiallodynic Effects to Drug Consumption and Effects of Intrathecal Analgesics (2007) (102)
Patient-controlled epidural analgesia during labor: a comparison of three solutions with a continuous infusion control. (1990) (102)
Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain (1999) (102)
Site of hemodynamic effects of intrathecal α2-adrenergic agonists (1991) (102)
Chronic constriction injury of sciatic nerve induces the up-regulation of descending inhibitory noradrenergic innervation to the lumbar dorsal horn of mice (2003) (102)
Cyclooxygenase 2 in infiltrating inflammatory cells in injured nerve is universally up-regulated following various types of peripheral nerve injury (2003) (101)
Preventing Chronic Pain After Surgery: Who, How, and When? (2005) (101)
Intrathecal Amitriptyline: Antinociceptive Interactions with Intravenous Morphine and Intrathecal Clonidine, Neostigmine, and Carbamylcholine in Rats (1995) (99)
Antiallodynic Effect of Intrathecal Gabapentin and Its Interaction with Clonidine in a Rat Model of Postoperative Pain (2000) (96)
Enhancement of analgesia from systemic opioid in humans by spinal cholinesterase inhibition. (1997) (96)
Role for both spinal cord COX-1 and COX-2 in maintenance of mechanical hypersensitivity following peripheral nerve injury (2002) (94)
Mindfulness-Meditation-Based Pain Relief Is Not Mediated by Endogenous Opioids (2016) (94)
Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats (2000) (94)
Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain (2003) (93)
A Multi‐center Study of Intrathecal Neostigmine for Analgesia following Vaginal Hysterectomy (1998) (92)
Predicting Acute Pain after Cesarean Delivery Using Three Simple Questions (2013) (90)
Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats (2008) (90)
Analgesic and hemodynamic effects of intrathecal clonidine as the sole analgesic agent during first stage of labor: a dose-response study. (1999) (89)
Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming. (2010) (88)
Preemptive hyperalgesia, not analgesia? (2000) (87)
Preliminary Efficacy Assessment of Intrathecal Injection of an American Formulation of Adenosine in Humans (2002) (86)
Cerebrospinal Fluid Norepinephrine and Acetylcholine Concentrations During Acute Pain (1996) (85)
Sex differences in cholinergic analgesia I: a supplemental nicotinic mechanism in normal females. (1999) (82)
Intravenous morphine increases release of nitric oxide from spinal cord by an alpha-adrenergic and cholinergic mechanism. (1997) (82)
Effects of estrogen on nitric oxide biosynthesis and vasorelaxant activity in sheep uterine and renal arteries in vitro. (1996) (81)
Phase I Human Safety Assessment of Intrathecal Neostigmine Containing Methyl- and Propylparabens (1997) (81)
Alfentanil, but Not Amitriptyline, Reduces Pain, Hyperalgesia, and Allodynia from Intradermal Injection of Capsaicin in Humans (1997) (79)
Spinal clonidine prolongs labor analgesia from spinal sufentanil and bupivacaine. (1999) (78)
Synergistic Effect between Intrathecal Non-NMDA Antagonist and Gabapentin on Allodynia Induced by Spinal Nerve Ligation in Rats (2000) (76)
Cyclooxygenase-1 in the Spinal Cord Is Altered after Peripheral Nerve Injury (2003) (73)
Age-dependent Responses to Thermal Hyperalgesia and Mechanical Allodynia in a Rat Model of Acute Postoperative Pain (2003) (73)
Cardiorespiratory and Spinal Cord Blood Flow Effects of Intrathecal Neostigmine Methylsulfate, Clonidine, and Their Combination in Sheep (1995) (73)
Perineural Clonidine Reduces Mechanical Hypersensitivity and Cytokine Production in Established Nerve Injury (2006) (72)
Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats. (1999) (71)
Intrathecal neostigmine and sufentanil for early labor analgesia. (1999) (70)
Role of Spinal NO in Antiallodynic Effect of Intrathecal Clonidine in Neuropathic Rats (1998) (69)
Relative potency of epidural to intrathecal clonidine differs between acute thermal pain and capsaicin-induced allodynia (2000) (68)
An isobolographic study of epidural clonidine and fentanyl after cesarean section. (1994) (68)
Neostigmine Counteracts Spinal Clonidine‐induced Hypotension in Sheep (1993) (67)
Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations (2015) (67)
Reversal of Peripheral Nerve Injury-induced Hypersensitivity in the Postpartum Period: Role of Spinal Oxytocin (2013) (65)
Epidural Fentanyl Produces Labor Analgesia by a Spinal Mechanism (1998) (65)
Oral Gabapentin Activates Spinal Cholinergic Circuits to Reduce Hypersensitivity after Peripheral Nerve Injury and Interacts Synergistically with Oral Donepezil (2007) (64)
α2-Adrenoceptor Stimulation Transforms Immune Responses in Neuritis and Blocks Neuritis-Induced Pain (2005) (64)
Pregnancy and Ephedrine Increase the Release of Nitric Oxide in Ovine Uterine Arteries (1996) (64)
Epidural clonidine after cesarean section. Appropriate dose and effect of prior local anesthetic. (1992) (63)
Management of Intrathecal Catheter‐Tip Inflammatory Masses: An Updated 2007 Consensus Statement From An Expert Panel (2008) (63)
Opioid-independent mechanisms supporting offset analgesia and temporal sharpening of nociceptive information (2012) (63)
The vascular mechanism of ephedrine's beneficial effect on uterine perfusion during pregnancy. (1991) (63)
0.125% ropivacaine is similar to 0.125% bupivacaine for labor analgesia using patient-controlled epidural infusion. (1998) (62)
Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery. (1999) (61)
Phase I safety assessment of intrathecal ketorolac (2002) (60)
The Effect of Peripherally Administered CDP-Choline in an Acute Inflammatory Pain Model: The Role of &agr;7 Nicotinic Acetylcholine Receptor (2009) (60)
Nicotinic Acetylcholine Receptor Regulation of Spinal Norepinephrine Release (2002) (60)
Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation (2003) (60)
Acetylcholine Stimulates the Release of Nitric Oxide from Rat Spinal Cord (1996) (60)
Perineural alpha(2A)-adrenoceptor activation inhibits spinal cord neuroplasticity and tactile allodynia after nerve injury. (2002) (59)
Intraplantar injection of a cyclooxygenase inhibitor ketorolac reduces immunoreactivities of substance p, calcitonin gene-related peptide, and dynorphin in the dorsal horn of rats with nerve injury or inflammation (2003) (58)
Intrathecal adenosine: interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative hypersensitivity. (1999) (58)
Cerebrospinal Fluid Pharmacokinetics and Pharmacodynamics of Intrathecal Neostigmine Methylsulfate in Humans (1998) (58)
Spinal nerve ligation increases α2-adrenergic receptor G-protein coupling in the spinal cord (2005) (57)
Intravenous clonidine produces hypoxemia by a peripheral alpha-2 adrenergic mechanism. (1988) (57)
Effect of Dexmedetomidine on Lumbar Cerebrospinal Fluid Pressure in Humans (1997) (57)
Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured rats (2014) (56)
Plasticity in Action of Intrathecal Clonidine to Mechanical but Not Thermal Nociception after Peripheral Nerve Injury (2003) (55)
Epidural Clonidine Does Not Decrease Blood Pressure or Spinal Cord Blood Flow in Awake Sheep (1988) (55)
NMDA causes release of nitric oxide from rat spinal cord in vitro (1994) (55)
Studies on the Safety of Glucose and Paraben-Containing Neostigmine for Intrathecal Administration (1997) (55)
Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain (2002) (55)
Epidural Neostigmine Produces Analgesia but Also Sedation in Women after Cesarean Delivery (2004) (54)
Intrathecal Neostigmine, but Not Sympathectomy, Relieves Mechanical Allodynia in a Rat Model of Neuropathic Pain (1998) (53)
Labor analgesia with epidural bupivacaine plus fentanyl: enhancement with epinephrine and inhibition with 2-chloroprocaine. (1990) (53)
Allosteric Adenosine Receptor Modulation Reduces Hypersensitivity Following Peripheral Inflammation by a Central Mechanism (2003) (53)
Spinal anesthesia: mechanisms, agents, methods, and safety. (1998) (52)
Spinal cholinergic alpha-2 adrenergic interactions in analgesia and hemodynamic control: role of muscarinic receptor subtypes and nitric oxide. (1994) (52)
Cephalad Movement of Morphine and Fentanyl in Humans after Intrathecal Injection (2003) (52)
Analgesic Doses of Intrathecal but Not Intravenous Clonidine Increase Acetylcholine in Cerebrospinal Fluid in Humans (1997) (51)
Estrogen Amplifies Pain Responses to Uterine Cervical Distension in Rats by Altering Transient Receptor Potential-1 Function (2007) (51)
Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia. (2002) (51)
Spinal &agr;2-Adrenoceptor-mediated Analgesia in Neuropathic Pain Reflects Brain-derived Nerve Growth Factor and Changes in Spinal Cholinergic Neuronal Function (2010) (50)
Toxicology Profile of N-Methyl-d-aspartate Antagonists Delivered by Intrathecal Infusion in the Canine Model (2008) (49)
Preoperative Inhibition of Cyclooxygenase-1 in the Spinal Cord Reduces Postoperative Pain (2005) (49)
Role of Spinal Cyclooxygenase in Human Postoperative and Chronic Pain (2010) (48)
Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain (2000) (48)
Effects of Intrathecal Ketorolac on Human Experimental Pain (2010) (48)
Individual differences in pain sensitivity: implications for treatment decisions. (2003) (48)
The Need for Large Clinical Studies in Perioperative Medicine (2012) (47)
Epidural clonidine analgesia in obstetrics: sheep studies. (1989) (46)
Intravenous Butorphanol, Meperidine, and Their Combination Relieve Pain and Distress in Women in Labor (2005) (46)
An evaluation of informed consent prior to epidural analgesia for labor and delivery. (2000) (46)
Chronic intrathecal morphine administration produces homologous mu receptor/G-protein desensitization specifically in spinal cord (2001) (46)
Epidural ketamine in healthy children--what's the point? (2003) (46)
Combined spinal-epidural analgesia in obstetrics. (1999) (45)
Intrathecal Sufentanil and Epidural Bupivacaine for Labor Analgesia: Dose‐Response of Individual Agents and in Combination (1998) (45)
Contribution of the Chemokine (C-C Motif) Ligand 2 (CCL2) to Mechanical Hypersensitivity after Surgical Incision in Rats (2010) (45)
Gabapentin Inhibits &ggr;-Amino Butyric Acid Release in the Locus Coeruleus but Not in the Spinal Dorsal Horn after Peripheral Nerve Injury in Rats (2012) (45)
Intrathecal ketorolac in dogs and rats. (2004) (45)
&agr;2-Adrenoceptor Activation by Clonidine Enhances Stimulation-evoked Acetylcholine Release from Spinal Cord Tissue after Nerve Ligation in Rats (2005) (44)
Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats (2002) (44)
Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms (2014) (44)
Oxytocin Inhibits the Membrane Depolarization-Induced Increase in Intracellular Calcium in Capsaicin Sensitive Sensory Neurons: A Peripheral Mechanism of Analgesic Action (2012) (44)
Spinal noradrenaline transporter inhibition by reboxetine and Xen2174 reduces tactile hypersensitivity after surgery in rats (2005) (43)
A Randomized Controlled Trial Comparing Two Multimodal Analgesic Techniques in Patients Predicted to Have Severe Pain After Cesarean Delivery (2016) (43)
Dose Response of Intrathecal Adenosine in Experimental Pain and Allodynia (2002) (43)
Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes. (2012) (43)
Clinical Effectiveness of Liposomal Bupivacaine Administered by Infiltration or Peripheral Nerve Block to Treat Postoperative Pain. (2020) (42)
Morphine-induced Spinal Release of Adenosine Is Reduced in Neuropathic Rats (2001) (42)
Intrathecal Morphine Reduces Allodynia after Peripheral Nerve Injury in Rats via Activation of a Spinal A1 Adenosine Receptor (2005) (42)
Intrathecal but not intravenous opioids release adenosine from the spinal cord. (2004) (41)
Maternally Administered Esmolol Produces Fetal β-Adrenergic Blockade and Hypoxemia in Sheep (1989) (41)
Age-dependent Responses to Nerve Injury– induced Mechanical Allodynia (2006) (41)
Peripheral Block of the Hyperpolarization-Activated Cation Current (Ih) Reduces Mechanical Allodynia in Animal Models of Postoperative and Neuropathic Pain (2005) (40)
Sex differences in cholinergic analgesia II: differing mechanisms in two models of allodynia. (1999) (40)
Uterine Cervical Distension Induces cFos Expression in Deep Dorsal Horn Neurons of the Rat Spinal Cord (2003) (40)
Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation (2004) (40)
Individual Differences in Acute Pain-induced Endogenous Analgesia Predict Time to Resolution of Postoperative Pain in the Rat (2015) (39)
Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation (2006) (39)
Estrogen Reduces Efficacy of μ- but Not κ-Opioid Agonist Inhibition in Response to Uterine Cervical Distension (2002) (39)
Inhibitory M2 muscarinic receptors are upregulated in both axotomized and intact small diameter dorsal root ganglion cells after peripheral nerve injury (2006) (39)
Four PGE2 EP receptors are up-regulated in injured nerve following partial sciatic nerve ligation (2003) (39)
Opioid antagonist adjuncts to epidural morphine for postcesarean analgesia: maternal outcomes. (1994) (38)
Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats (2005) (38)
Subarachnoid Neostigmine Potentiation of Alpha2-Adrenergic Agonist Analgesia: Dexmedetomidine versus Clonidine (1994) (38)
To our readers: an experiment in education. (2010) (38)
Neostigmine Decreases Bupivacaine Use by Patient-Controlled Epidural Analgesia During Labor: A Randomized Controlled Study (2009) (37)
Phase I Safety Assessment of Intrathecal Injection of an American Formulation of Adenosine in Humans (2002) (37)
Epinephrine Enhances Analgesia Produced by Epidural Bupivacaine during Labor (1987) (37)
Preclinical toxicity screening of intrathecal adenosine in rats and dogs. (1999) (37)
Site of hemodynamic effects of intrathecal alpha 2-adrenergic agonists. (1991) (37)
Oral Donepezil Reduces Hypersensitivity after Nerve Injury by a Spinal Muscarinic Receptor Mechanism (2007) (37)
Allosteric Adenosine Modulation to Reduce Allodynia (2001) (37)
Comparison of analgesic requirements after liver transplantation and cholecystectomy. (1989) (37)
Epinephrine enhances analgesia produced by epidural bupivacaine during labor. (1987) (36)
Allosteric modulation of adenosine A1 receptor coupling to G‐proteins in brain (2005) (36)
Spinal Nitric Oxide Mediates Antinociception from Intravenous Morphine (1998) (36)
Location and Characteristics of Nitric Oxide Synthase in Sheep Spinal Cord and Its Interaction with alpha sub 2 -Adrenergic and Cholinergic Antinociception (1996) (36)
Spinal Adrenergic and Cholinergic Receptor Interactions Activated by Clonidine in Postincisional Pain (2003) (35)
Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury (2011) (35)
Analgesic and Hemodynamic Effects of Intrathecal Clonidine as the Sole Analgesic Agent During First Stage of Labor: A Dose-Response Study (2000) (35)
α2-adrenoceptors inhibit the intracellular Ca2+ response to electrical stimulation in normal and injured sensory neurons, with increased inhibition of calcitonin gene-related peptide expressing neurons after injury (2005) (35)
Data fabrication and article retraction: how not to get lost in the woods. (2009) (35)
Multiplicative interactions to enhance gabapentin to treat neuropathic pain. (2008) (34)
Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus (2015) (34)
Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat (2010) (33)
Uterine Cervical Afferents in Thoracolumbar Dorsal Root Ganglia Express Transient Receptor Potential Vanilloid Type 1 Channel and Calcitonin Gene–related Peptide, but Not P2X3 Receptor and Somatostatin (2006) (33)
Safety in numbers: how do we study toxicity of spinal analgesics? (2002) (33)
Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome (2015) (32)
Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus (2016) (32)
Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis (2007) (32)
Hyperexcitability of axotomized and neighboring unaxotomized sensory neurons is reduced days after perineural clonidine at the site of injury. (2005) (32)
Letter: Very fast zinc-catalyzed hydrolysis of an anhydride. A model for the rate and mechanism of carboxypeptidase A catalysis. (1975) (32)
Three Novel Spinal Analgesics: Clonidine, Neostigmine, Amitriptyline (1996) (32)
Intrathecal clonidine in obstetrics: sheep studies. (1990) (32)
Immunocytochemical localization of the α3, α4, α5, α7, β2, β3 and β4 nicotinic acetylcholine receptor subunits in the locus coeruleus of the rat (2003) (31)
Intrathecal S-nitroso-N-acetylpenicillamine and l-cysteine attenuate nerve injury-induced allodynia through noradrenergic activation in rats (2000) (31)
Echocardiographic evaluation of patients with blunt chest injury: correlation with perioperative hypotension. (1986) (31)
Intrathecal clonidine and the response to hemorrhage. (1990) (31)
Intrathecal Lidocaine Reverses Tactile Allodynia Caused by Nerve Injuries and Potentiates the Antiallodynic Effect of the COX Inhibitor Ketorolac (2003) (31)
Reporting of Observational Research in ANESTHESIOLOGY: The Importance of the Analysis Plan. (2016) (31)
Chronic estrogen sensitizes a subset of mechanosensitive afferents innervating the uterine cervix. (2005) (31)
A Physiologic Assessment of Intrathecal Amitriptyline in Sheep (1997) (31)
Knock down of the α5 nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia (2005) (30)
Role of Adenosine Receptors in Spinal G-Protein Activation after Peripheral Nerve Injury (2002) (30)
Effects of Intrathecal Neostigmine, Bupivacaine, and Their Combination on Sympathetic Nerve Activity in Rats (1997) (30)
Antinociceptive and hemodynamic effects of a novel alpha2-adrenergic agonist, MPV-2426, in sheep. (1999) (30)
Checklist for the preparation and review of pain clinical trial publications: a pain-specific supplement to CONSORT (2017) (30)
Abdominal Surgery Decreases Food-reinforced Operant Responding in Rats: Relevance of Incisional Pain (2005) (30)
Computer-controlled Epidural Infusion to Targeted Cerebrospinal Fluid Concentrations in Humans: Clonidine (1995) (30)
Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury. (2013) (29)
Alpha-2 agonists and analgesia (1994) (29)
Peripheral nerve injury and gabapentin, but not their combination, impair attentional behavior via direct effects on noradrenergic signaling in the brain (2014) (29)
Adenosine Reduces Glutamate Release in Rat Spinal Synaptosomes (2005) (29)
Severe maternal hypotension and fetal bradycardia after a combined spinal epidural anesthetic. (1997) (29)
Effect of prior anesthetic solution on epidural morphine analgesia. (1991) (29)
Intrathecal alpha 2-adrenergic agonists stimulate acetylcholine and norepinephrine release from the spinal cord dorsal horn in sheep. An in vivo microdialysis study. (1997) (28)
Adherence to recommended practices for perioperative anesthesia care for older adults among US anesthesiologists: results from the ASA Committee on Geriatric Anesthesia-Perioperative Brain Health Initiative ASA member survey (2020) (28)
Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile rats. (2010) (28)
Future Directions for Intrathecal Pain Management: A Review and Update From the Interdisciplinary Polyanalgesic Consensus Conference 2007 (2008) (28)
The need for a journal policy on intrathecal, epidural, and perineural administration of non-approved drugs (2010) (26)
Effect of pregnancy and pain on cerebrospinal fluid immunoreactive enkephalins and norepinephrine in healthy humans (1990) (26)
Preclinical Toxicity Screening of Intrathecal Oxytocin in Rats and Dogs (2014) (25)
Textbook of Pain, 4th Edition. (2001) (25)
The Pain of Childbirth and Its Effect on the Mother and the Fetus (2009) (25)
Peripheral Nerve Injury Sensitizes the Response to Visceral Distension but Not Its Inhibition by the Antidepressant Milnacipran (2004) (25)
Aspirin, the miracle drug: spinally, too? (1993) (25)
Wherefore Gabapentinoids?: Was There Rush Too Soon to Judgment? (2016) (25)
Day-to-day experience in resolution of pain after surgery (2017) (25)
Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents. (2015) (25)
Epidural neostigmine: will it replace lipid soluble opioids for postoperative and labor analgesia? (2009) (25)
Spinal Adenosine Receptor Activation Reduces Hypersensitivity after Surgery by a Different Mechanism Than after Nerve Injury (2004) (24)
Intrathecal Morphine Reduces the Visceromotor Response to Acute Uterine Cervical Distension in an Estrogen-independent Manner (2003) (24)
Preoperative Sciatic Nerve Block Decreases Mechanical Allodynia More in Young Rats: Is Preemptive Analgesia Developmentally Modulated? (2004) (24)
An Obligatory Role for Spinal Cholinergic Neurons in the Antiallodynic Effects of Clonidine after Peripheral Nerve Injury (2001) (24)
Relief of Hypersensitivity after Nerve Injury from Systemic Donepezil Involves Spinal Cholinergic and &ggr;-Aminobutyric Acid Mechanisms (2013) (24)
Fetal Heart Rate Variability After Epidural Fentanyl During Labor (1990) (23)
Spinal cord dynorphin expression increases, but does not drive microglial prostaglandin production or mechanical hypersensitivity after incisional surgery in rats (2006) (23)
Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Pain: A Randomized, Sham-controlled Pilot Study (2021) (23)
Sex Differences in Cholinergic Analgesia II: Differing Mechanisms in Two Models of Allodynia (2000) (23)
Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury. (2012) (22)
The puerperium alters spinal cord plasticity following peripheral nerve injury (2013) (22)
Does Dextrose Affect Analgesia or the Side Effects of Intrathecal Sufentanil? (1997) (22)
Pharmacology of Opioid Inhibition to Noxious Uterine Cervical Distension (2002) (22)
Did experimenter bias conceal the efficacy of spinal opioids in previous studies with the spinal nerve ligation model of neuropathic pain? (2004) (22)
Epidemiology of Pain. (2000) (22)
Ondansetron Reverses Antihypersensitivity from Clonidine in Rats after Peripheral Nerve Injury: Role of &ggr;-Aminobutyric Acid in &agr;2-Adrenoceptor and 5-HT3 Serotonin Receptor Analgesia (2012) (22)
Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats (2010) (22)
Skin incision-induced receptive field responses of mechanosensitive peripheral neurons are developmentally regulated in the rat. (2012) (22)
Magnesium, anesthesia, and hemodynamic control. (1991) (21)
S-nitroso-l-cysteine releases norepinephrine in rat spinal synaptosomes 1 1 Published on the World Wide Web on 20 June 2000. (2000) (21)
Intrathecal Adenosine following Spinal Nerve Ligation in Rat: Short Residence Time in Cerebrospinal Fluid and No Change in A1 Receptor Binding (2002) (21)
Cystatin C in cerebrospinal fluid is not a diagnostic test for pain in humans (2004) (21)
Spinal Neostigmine Diminishes, but Does Not Abolish, Hypotension from Spinal Bupivacaine in Sheep (1996) (21)
Predictors of Headache Before, During, and After Pregnancy: A Cohort Study (2012) (21)
Intrathecal Clonidine for Postoperative Analgesia in Elderly Patients: The Influence of Baricity on Hemodynamic and Analgesic Effects (2004) (20)
Repeated Dosing with Oral Allosteric Modulator of Adenosine A1 Receptor Produces Tolerance in Rats with Neuropathic Pain (2004) (20)
Previous wet tap does not reduce success rate of labor epidural analgesia. (1994) (20)
Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors (2011) (20)
New epidural drugs: primum non nocere. (1998) (20)
ST91 [2-(2,6-Diethylphenylamino)-2-imidazoline Hydrochloride]-Mediated Spinal Antinociception and Synergy with Opioids Persists in the Absence of Functional α-2A- or α-2C-Adrenergic Receptors (2007) (20)
Treating and Preventing Chronic Pain: A View From the Spinal Cord—Bonica Lecture, ASRA Annual Meeting, 2005 (2005) (19)
PHARMACOKINETIC AND DYNAMIC STUDIES OF INTRATHECAL, EPIDURAL, AND INTRAVENOUS DEXMEDETOMIDINE (1991) (19)
Morphine-induced spinal cholinergic activation: in vivo imaging with positron emission tomography (2001) (19)
Intrathecal Clonidine Reduces Hypersensitivity After Nerve Injury by a Mechanism Involving Spinal m4 Muscarinic Receptors (2003) (19)
A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. (2011) (19)
Acute Paediatric Pain Management: A Practical Guide. (2000) (18)
Is ST Segment Depression of the Electrocardiogram During Cesarean Section Merely Due to Cardiac Sympathetic Block? (1994) (18)
Pupil responses and pain ratings to heat stimuli: Reliability and effects of expectations and a conditioning pain stimulus (2017) (18)
Disruption of Spinal Noradrenergic Activation Delays Recovery of Acute Incision-Induced Hypersensitivity and Increases Spinal Glial Activation in the Rat. (2016) (18)
Nociceptor-selective Peripheral Nerve Block Induces Delayed Mechanical Hypersensitivity and Neurotoxicity in Rats (2014) (18)
Vasopressin and fetal cerebrovascular regulation. (1992) (18)
Liposomal Bupivacaine Infiltration for Knee Arthroplasty: Significant Analgesic Benefits or Just a Bunch of Fat? (2018) (17)
Norepinephrine Release from Spinal Synaptosomes: Auto-&agr;2-adrenergic Receptor Modulation (2000) (17)
Overview: First International Symposium on α2-Adrenergic Mechanisms of Spinal Anesthesia (1993) (17)
Phase 1 Safety Assessment of Intrathecal Oxytocin (2015) (16)
A Pain Model After Gynecologic Surgery: The Effect of Intrathecal and Systemic Morphine (2006) (16)
Formation of 6-nitro-norepinephrine from nitric oxide and norepinephrine in the spinal cord and its role in spinal analgesia (2000) (16)
Developmental Differences in Spinal Cyclooxygenase 1 Expression after Surgical Incision (2006) (16)
Systemic, but not intrathecal ketorolac is antinociceptive to uterine cervical distension in rats (2003) (16)
EPIDURAL CLONIDINE FOR REFRACTORY REFLEX SYMPATHETIC DYSTROPHY (1991) (16)
Electrophysiologic Characteristics of Large Neurons in Dorsal Root Ganglia during Development and after Hind Paw Incision in the Rat (2008) (16)
Maternal and fetal effects of labetalol in pregnant ewes. (1991) (16)
Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons (2006) (16)
Atraucan®: A New Needle for Spinal Anesthesia (1993) (16)
Additives for Epidural Analgesia for Labor: Why Bother? (1998) (16)
Assessment of attention threshold in rats by titration of visual cue duration during the five choice serial reaction time task (2015) (15)
Pregnancy Increases Excitability of Mechanosensitive Afferents Innervating the Uterine Cervix (2008) (15)
2008 in Review: Advancing Medicine in Anesthesiology (2008) (15)
Intrathecal Ketorolac Reverses Hypersensitivity following Acute Fentanyl Exposure (2002) (14)
Patterns of recovery from pain after cesarean delivery (2018) (14)
Descending Noradrenergic Inhibition: An Important Mechanism of Gabapentin Analgesia in Neuropathic Pain. (2018) (14)
Immunocytochemical localization of the alpha3, alpha4, alpha5, alpha7, beta2, beta3 and beta4 nicotinic acetylcholine receptor subunits in the locus coeruleus of the rat. (2003) (14)
Intravenous clonidine hydrochloride toxicity in pregnant ewes. (1989) (14)
Is ST segment depression of the electrocardiogram during cesarean section merely due to cardiac sympathetic block (1994) (14)
Regional anesthesia: vintage Bordeaux (and Napa Valley) (1997) (14)
Assessment of Behavior during Labor in Rats and Effect of Intrathecal Morphine (2008) (13)
Intrathecal Administration of a Cylcooxygenase-1, but Not a Cyclooxygenase-2 Inhibitor, Reverses the Effects of Laparotomy on Exploratory Activity in Rats (2006) (13)
Failure of intrathecal ketorolac to reduce remifentanil-induced postinfusion hyperalgesia in humans (2015) (13)
Intrathecal Ketorolac Enhances Antinociception from Clonidine (2003) (13)
Clonidine-induced Neuronal Activation in the Spinal Cord Is Altered after Peripheral Nerve Injury (2003) (13)
Patient controlled epidural analgesia during labor, or whose finger do you want on the button? (1993) (13)
Psychosocial Stress Delays Recovery of Postoperative Pain Following Incisional Surgery in the Rat (2018) (13)
Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from α2-adrenoceptor stimulation (2007) (13)
Fishing for genes: practical ways to study genetic polymorphisms for pain. (2004) (12)
ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. (2007) (12)
Lipid Soluble Opioids Do Move in Cerebrospinal Fluid (2000) (12)
Pain after surgery. (2018) (12)
Combined Spinal-Epidural Analgesia in Obstetrics (1999) (12)
Research approaches for evaluating opioid sparing in clinical trials of acute and chronic pain treatments: IMMPACT recommendations. (2021) (12)
P75-expressing elements are necessary for anti-allodynic effects of spinal clonidine and neostigmine (2001) (12)
Electrical Field Stimulation to Study Inhibitory Mechanisms in Individual Sensory Neurons in Culture (2004) (12)
Slow repair of X-ray-induced DNA damage in rat 9L cells in vitro analyzed by viscoelastometry. (1981) (12)
Maternally administered esmolol produces fetal beta-adrenergic blockade and hypoxemia in sheep. (1990) (12)
Analgesia induced by perineural clonidine is enhanced in persistent neuritis (2007) (11)
Metoclopramide Exaggerates Stress-Induced Tachycardia in Pregnant Sheep (1996) (11)
Estrogen Reduces Efficacy of &mgr;- but Not &kgr;-Opioid Agonist Inhibition in Response to Uterine Cervical Distension (2002) (11)
Recovery of physical activity after cesarean delivery and its relationship with pain. (2019) (10)
Modeling Individual Recovery after Peripheral Nerve Injury in Rats and the Effects of Parturition (2014) (10)
Peripheral oxytocin restores light touch and nociceptor sensory afferents towards normal after nerve injury (2019) (10)
The Monoamine Reuptake Inhibitor Milnacipran Does Not Affect Nociception to Acute Visceral Distension in Rats (2004) (10)
Ambulatory continuous peripheral nerve blocks to treat postamputation phantom limb pain: a multicenter, randomized, quadruple-masked, placebo-controlled clinical trial (2020) (10)
Down-regulation of astroglial glutamate transporter-1 in the locus coeruleus impairs pain-evoked endogenous analgesia in rats (2015) (10)
The antinociceptive effects of spinal cyclooxygenase inhibitors on uterine cervical distension (2004) (10)
Demonstrating safety of subarachnoid calcitonin: patients or animals? (1988) (10)
Labor pain (1990) (10)
Reporting of Preclinical Research in Anesthesiology: Transparency and Enforcement. (2016) (9)
Epidural Clonidine Analgesia in Obstetrics: Sheep Studies (1989) (9)
Epidural Neostigmine versus Fentanyl to Decrease Bupivacaine Use in Patient-controlled Epidural Analgesia during Labor: A Randomized, Double-blind, Controlled Study (2017) (9)
Incisional Nociceptive Input Impairs Attention-related Behavior and Is Associated with Reduced Neuronal Activity in the Prefrontal Cortex in Rats (2018) (9)
Intrathecal ketorolac does not improve acute or chronic pain after hip arthroplasty: a randomized controlled trial (2014) (9)
Replication to advance science: changes in ANESTHESIOLOGY. (2014) (9)
Bolus Metoclopramide Does Not Enhance Morphine Analgesia After Cesarean Section (1996) (9)
Effect of Cyclooxygenase-1 Inhibition in Postoperative Pain Is Developmentally Regulated (2004) (9)
Evaluation of Informed Consent for Anesthesia for Labor and Delivery (1988) (9)
Gestational Obstructive Sleep Apnea: Biomarker Screening Models and Lack of Postpartum Resolution. (2018) (9)
Obstetric anesthesia: what have you done for us lately? (1999) (8)
Developmental differences in peripheral glabrous skin mechanosensory nerve receptive field and intracellular electrophysiologic properties: phenotypic characterization in infant and juvenile rats (2011) (8)
Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury (2018) (8)
Dose Response study of spinal fentanyl in early labor (1998) (8)
Tachykinins modulate nociceptive responsiveness and sensitization: In vivo electrical characterization of primary sensory neurons in tachykinin knockout (Tac1 KO) mice (2019) (8)
EVALUATION OF 2-CHLOROPROCAINE AS AN EFFECTIVE INTRAVENOUS TEST DOSE FOR EPIDURAL ANALGESIA (1987) (8)
About Our Authors (1955) (8)
Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task. (2017) (8)
Gabapentin Inhibits -Amino Butyric Acid Release in the Locus Coeruleus but Not in the Spinal Dorsal Horn after Peripheral Nerve Injury in Rats (2012) (8)
The Internet: where do we want to go tomorrow? (1998) (8)
6-NO(2)-norepinephrine increases norepinephrine release and inhibits norepinephrine uptake in rat spinal synaptosomes. (2000) (8)
Recovery from nerve injury induced behavioral hypersensitivity in rats parallels resolution of abnormal primary sensory afferent signaling. (2020) (7)
Mechanical sensibility of nociceptive and non-nociceptive fast-conducting afferents is modulated by skin temperature. (2016) (7)
Conducting Research in Anaesthesia and Intensive Care Medicine (2002) (7)
Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation. (2007) (7)
Case reports are leaving Anesthesiology, but not the specialty. (2013) (7)
Labor Analgesia from Spinal Neostigmine Combined with Spinal Sufentanil, Bupivacaine, and Clonidine (1999) (7)
Clinical Anesthesia, 3rd Edition. (1999) (7)
Evaluation Of Lidocaine As An Intravenous Test Dose For Epidural Anesthesia (1988) (7)
Sex Differences in Analgesia from Intrathecal Neostigmine in Humans (1998) (7)
Postoperative Analgesic Effects with Intrathecal Neostigmine in Sheep (1994) (7)
Overview: First International Symposium on α2-Adrenergic Mechanisms of Spinal Anesthesia (1993) (7)
Capsaicin‐induced pain and sensitisation in the postpartum period (2019) (6)
A898 Dose Response Study of Intrathecal Sufentanil in Laboring Patients (1997) (6)
Intrathecal Neostigmine for Post-Cesarean Section Analgesia: Dose Response (1997) (6)
Perineural 2 A-Adrenoceptor Activation Inhibits Spinal Cord Neuroplasticity and Tactile Allodynia after Nerve Injury (2002) (6)
Anesthesiology and the press. (2007) (6)
A872 Phase I evaluation of intrathecal neostigmine for labor analgesia (1997) (6)
In vivo imaging of the spinal cord cholinergic system with PET. (1999) (6)
Consent contraindicated? (2010) (6)
NEW EPIDURAL DRUGS : PRIMUM NON NOCERE. AUTHORS' REPLIES (1998) (6)
LABETALOL TREATMENT OF NOREPINEPHRINE INDUCED HYPERTENSION IN THE GRAVID EWE (1986) (6)
Studying Tacit Knowledge in Anesthesiology A Role for Qualitative Research (2009) (5)
Respiratory depression following intrathecal opioids. (1991) (5)
A Painful Beginning: Early Life Surgery Produces Long-Term Behavioral Disruption in the Rat (2021) (5)
ASA Annual Meeting Abstracts (1999) (5)
Without Science There Is Little Art in Anesthesiology: 2015 Rovenstine Lecture (2016) (5)
EFFECT OF EPINEPHRINE ON THE DURATION OF ANALGESIA WITH EPIDURAL BUPIVACAINE AND FENTANYL (1987) (5)
Concerns Regarding Ultrasound-guided Regional Anesthesia (2009) (4)
Journal-related and other special activities at the 2008 American Society of Anesthesiologists Annual Meeting. (2008) (4)
VERY FAST ZINC‐CATALYZED HYDROLYSIS OF AN ANHYDRIDE, A MODEL FOR THE RATE AND MECHANISM OF CARBOXYPEPTIDASE A CATALYSIS (1975) (4)
Sex Differences in Cholinergic Analgesia I: A Supplemental Nicotinic Mechanism in Normal Females (2000) (4)
2007 in Review: A Dozen Steps Forward in Anesthesiology (2008) (4)
INTRAVENOUS CLONIDINE PRODUCES HYPOXEMIA (1987) (4)
EFFECT OF EPINEPHRINE ON THE DURATION OF ANALGESIA WITH EPIDURAL BUPIVACAINE (1986) (4)
Post-discharge hyperpolarization is an endogenous modulatory factor limiting input from fast-conducting nociceptors (AHTMRs) (2017) (4)
The treatment of pain: remaining challenges and future opportunities (2002) (4)
Percutaneous Neuromodulation of the Brachial Plexus and Sciatic Nerve for the Treatment of Acute Pain Following Surgery: Secondary Outcomes From a Multicenter, Randomized, Controlled Pilot Study. (2021) (4)
Immediate Effects of a Continuous Peripheral Nerve Block on Postamputation Phantom and Residual Limb Pain: Secondary Outcomes From a Multicenter Randomized Controlled Clinical Trial (2021) (4)
Phase I Safety Assessment of Spinal Neostigmine in Volunteers (1994) (4)
Patient Controlled Epidural Analgesia (PCEA) During LaborA Comparison of Three Solutions with Continuous Epidural Infusion (CEI) Control (1988) (4)
How Do We Measure (the Cost of) Pain Relief? (2000) (4)
Mechanism of antiarrhythmic effect of dexmedetomidine on epinephrine-induced arrhythmias. (1991) (4)
Spinal Anesthesia: Mechanisms, Agents, Methods, and Safety (1998) (4)
Nociceptive input after peripheral nerve injury results in cognitive impairment and alterations in primary afferent physiology in rats. (2020) (4)
Ketamine fails to prevent postoperative delirium (2017) (4)
Chronic activation of spinal adenosine A1 receptors results in hypersensitivity (2006) (4)
Sex Differences in Cholinergic Analgesia in Normal Rats (1998) (4)
Distinguished achievement award. (1972) (3)
Systemic Opioids Stimulate Norepinephrine Release from Sheep Spinal Cord: An In Vivo Microdialysis Study (1994) (3)
It's all in how you read the label. (1999) (3)
Spinal Exparel®-an extended duration of preclinical study needed. (2019) (3)
Science, Medicine, and the AnesthesiologistTwo Pages to Keep You Abreast of Key Papers from Outside the Specialty and Relevant to Your Practice (2015) (3)
Spinal norepinephrine release from nitric oxide species is not increased following peripheral nerve injury in rats (2002) (3)
Update on spinal cord pharmacology in pain (1997) (3)
International Association for the Study of Pain 9th World Congress on Pain. (2000) (3)
Studying Tacit Knowledge in Anesthesiology (2009) (3)
Peripheral nerve injury in rats induces alternations in choice behavior associated with food reinforcement (2019) (3)
Perineural &;2A-Adrenoceptor Activation Inhibits Spinal Cord Neuroplasticity and Tactile Allodynia after Nerve Injury (2002) (3)
Anesthesiology: Attracting the Best New Science in the Specialty. (2015) (3)
Antinociceptive Interaction between Intrathecal Sufentanil and Epidural Bupivacaine: Additivity of Synergism? (1994) (3)
Pharmacokinetics of Spinal Neostigmine in Humans (1994) (3)
EPIDURAL CLONIDINE ANTINOCICEPTION IN SHEEP (1986) (3)
Blood Pressure, but Not Cerebrospinal Fluid Fentanyl Concentration, Predicts Duration of Labor Analgesia from Spinal Fentanyl (2010) (3)
Blockade of α2-adrenergic or metabotropic glutamate receptors induces glutamate release in the locus coeruleus to activate descending inhibition in rats with chronic neuropathic hypersensitivity (2018) (3)
Improving Preclinical Development of Novel Interventions to Treat Pain: Insanity Is Doing the Same Thing Over and Over and Expecting Different Results (2022) (3)
Regional Anesthesia: Advancing the Practice of Medicine; The 2008 Gaston Labat Award Lecture (2008) (2)
Intrathecal and epidural opioids (1997) (2)
The Interaction between Intrathecal Neostigmine and α2 Agonists (1994) (2)
Can You Imagine That?Progress in Communication in Medicine (2007) (2)
Fraud in anesthesia - an editor's perspective. (2013) (2)
Heterogeneity in patterns of pain development after nerve injury in rats and the influence of sex (2021) (2)
Note of editorial concern. (2011) (2)
Systemic administration of a β2-adrenergic receptor agonist reduces mechanical allodynia and suppresses the immune response to surgery in a rat model of persistent post-incisional hypersensitivity (2021) (2)
A907 0.125% ROPIVACAINE IS NOT SUPERIOR TO 0.125% BUPIVACAINE FOR LABOR ANALGESIA UTILIZING PCEA (1997) (2)
Exogenous and endogenous adenosine enhances spinal morphine analgesia (1998) (2)
Side Effects of Analgesia from Spinal Neostigmine Injected through a Whitacre Needle (1994) (2)
Chapter 6 Epidural and Spinal Opioids (1993) (2)
New understanding and treatment of acute pain (1992) (2)
PRELIMINARY CHARACTERIZATION OF -α2-ADRENOCEPTORS IN THE SHEEP SPINAL CORD BY AUTORADIOGRAPHY (1991) (2)
Intrathecal Sufentanil and Epidural Bupivacaine for Labor Analgesia: Dose-Response of Individual Agents and in Combination (1998) (2)
Can a Blood Test of Immune Responsiveness Predict Speed of Recovery from Pain and Dysfunction after Surgery? (2015) (2)
Fospropofol Assay Issues and Impact on Pharmacokinetic and Pharmacodynamic Evaluation: Retracted (2008) (2)
Postoperative neurocognitive dysfunction in elderly patients after xenon versus propofol anesthesia for major noncardiac surgery: a double-blinded randomized controlled pilot study: retraction. (2014) (2)
High Altitude Medicine. (2000) (2)
INTRAVENOUS REGIONAL ANESTHESIA: EFFECT OF TOURNIQUET SIZE AND TYPE ON LEAKAGE UNDER THE TOURNIQUET (1987) (2)
Patient safety: anesthesiology contributions and supplements to the American Society of Anesthesiologists' Annual Meeting. (2013) (2)
EFFECTS OF EPIDURAL CLONIDINE IN PREGNANT EWES (1987) (2)
Combined Spinal–Epidural Analgesia in Labor (2000) (2)
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Pragmatic Effectiveness Trial of a Nonpharmacologic Alternative for the Treatment of Postoperative Pain. (2020) (2)
PATIENT CONTROLLED EPIDURAL ANALGESIA (PCEA) FOR LABOR (1989) (2)
Spinal Clonidine Hypotension: Mechanism of Reversal by Spinal Neostigmine (1993) (1)
The Hemodynamic and Spinal Cord Blood Flow Effects of Intrathecal Neostigmine in Sheep (1994) (1)
Randomized controlled trial of intrathecal oxytocin on speed of recovery after hip arthroplasty. (2022) (1)
Comparing the Efficacy of Epidural Opiates with that of Patient-controlled Analgesia (1988) (1)
Preoperative Sciatic Nerve Block (SNB) Decreases Mechanical Hyperalgesia More Than Postoperative SNB in an Acute Pain Model in Young Rats: Is Preemptive Analgesia Developmentally Modulated?: [2002][A-962] (2002) (1)
In Search of Excellence in Anesthesiology (2008) (1)
Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management, 4th Edition. (1999) (1)
Blood Conservation Techniques and Platelet Function in Cardiac Surgery: Retraction. (2015) (1)
α2-Adrenergic Agonists in Anesthesia Practice (1999) (1)
Predicting Acute Pain After Cesarean Delivery Using 3 Simple Questions (2014) (1)
INTRATHECAL CLONIDINE AND NEOSTIGMINE BUT NOT SYMPATHECTOMY RELIEVES MECHANICAL ALLODYNIA IN A RAT MODEL OF NEUROPATHIC PAIN (1998) (1)
Sex differences in spinal cholinergic analgesia following capsaicin (1998) (1)
Cerebrospinal Fluid (CSF) Pharmacodynamics and a Possible Cholinergic Mechanism of Epidural Clonidine Analgesia in Humans (1992) (1)
Metoclopramide Exaggerates Stress-Induced Tachycardia (1988) (1)
Location, location, location. (2000) (1)
Seeding of breast cancer cell line (MDA-MB-231LUC+) to the mandible induces overexpression of substance P and CGRP throughout the trigeminal ganglion and widespread peripheral sensory neuropathy throughout all three of its divisions (2021) (1)
Offset analgesia in Complex Regional Pain Syndrome (2012) (1)
Future Trends in Basic Science Pain Research (2004) (1)
MATERNALLY ADMINISTERED LABETALOL PRODUCES LESS ADRENERGIC BLOCKADE IN FETUS THAN IN MOTHER (1989) (1)
EPIDURAL CLONIDINE FOR INTRACTABLE CANCER PAIN MANAGEMENT (1989) (1)
Science marches forward: a new tool to study the progress of labor. (2009) (1)
Maternally Administered Esmolol Produces Fetal β-Blockade and Hypoxemia (1988) (1)
(551) Mindfulness meditation-induced pain relief does not require endogenous opioidergic systems. (2016) (1)
INTRAVENOUS CLONIDINE PRODUCES FETAL HYPOXEHIA (1987) (1)
(247) Studying Pain Neural Circuits with Viral Vector rAAV2-Retro in the Brain (2019) (1)
Recovery of Physical Activity After Cesarean Delivery and Its Relationship With Pain (2020) (1)
Ethical Concerns Regarding Human Study (2016) (1)
Capsaicin-induced Pain and Sensation in the Postpartum Period (2019) (1)
FAER-ing Well in Academic Anesthesiology (2017) (1)
Postoperative Analgesia Following Intrathecal Clonidine or Clonidine + Neostigmine In Elective Cesarean Section Patients (1999) (1)
Cerebrospinal Fluid (CSF) Pharmacokinetics and Pharmacodynamics of Epidural Clonidine in Humans (1992) (1)
Intrathecal Clonidine Reduces Acute Pain More than IV Clonidine (1998) (1)
A902 Spinal neostigmine does not reduce post-cesarean section morphine use (1997) (1)
MORPHINE'S SITE OF ACTION FOR ANALGESIA TO UTERINE CERVICAL DISTENSION IS CENTRAL AND ANTAGONIZED BY ESTROGEN: BP‐3 (2002) (1)
Washington University and the why of anesthesiology. (2011) (1)
Preliminary results from a randomized, controlled, cross-over trial of intrathecal oxytocin for neuropathic pain. (2023) (0)
A797 Low-dose epidural fentanyl infusions produce analgesia by a spinal effect (1997) (0)
Announcement and Call for Abstracts: 2014 Annual Journal Symposium (2011) (0)
Spinal 2-Adrenergic Agonists for Intractable Cancer Pain (2003) (0)
Topical Seminar Abstracts (2009) (0)
For Anesthesiology to Thrive We Need More Physician-Scientists … and That’s What FAER Aims to Do (2017) (0)
Curiosity, discipline, and joy; and the greatest of these is joy. (2009) (0)
Potency and Efficacy of Clonidine and ST 91 in a Rat Model for Human Postoperative Pain: [2002][A-964] (2002) (0)
developmentally regulated in the rat mechanosensitive peripheral neurons are Skin incision-induced receptive field responses of (2015) (0)
FAER … and Ethics (2018) (0)
Education: A New Focus and a New Section of Anesthesiology (2010) (0)
Tracheal Intubation: Theory and Practice. (1999) (0)
Patient-centered results from a multicenter study of continuous peripheral nerve blocks and postamputation phantom and residual limb pain: secondary outcomes from a randomized, clinical trial (2023) (0)
Intrathecal Neostigmine Potentiates the Analgesic Effects of Interathecal Clonidine (1992) (0)
The Need for Perspective. Authors' reply (2009) (0)
Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial (2022) (0)
Temperature Effects on Somal Membrane Properties Neurons Recorded Intracellularly In Vivo: Physiological Properties of Mouse Skin Sensory (2015) (0)
Dorsal Horn Neurons the Electrophysiological Properties of Neonatal Rat Age-Dependent Effects of Peripheral Inflammation on (2015) (0)
VASOPRESSIN DILATES CEREBRAL ARTERIES IN FETAL SHEEP (1991) (0)
Spinal nociceptive mechanisms (2004) (0)
FAER: A Growing Force (2017) (0)
Trigeminal Ganglion Neurons Postnatal Changes in Membrane Properties of Mice (2015) (0)
Why I Donate to FAER During a Recession (2010) (0)
FAER … and TRAUMA (2018) (0)
New Agents to Clinical Practice: Introduction to Clinical Trials (1996) (0)
Epidural clonidine in sheep: Hemodynamic and spinal cord blood flow effects (1987) (0)
A551 VASOPRESSIN CONSTRICTS PERIPHERAL, BUT DILATES CEREBRAL ARTERIES (1990) (0)
Nominations Sought for 2015 ASA Presidential Scholar Award (2011) (0)
DOES ANESTHESIOLOGY, LIKE HISTORY, REPEAT ITSELF? AUTHORS' REPLY (1998) (0)
EFFECT OF CATHETER TESTING WITH 2-CHLOROPROCAINE ON THE DURATION OF EPIDURAL MORPHINE ANALGESIA FOLLOWING CESAREAN SECTION (1989) (0)
Science and the mission of anesthesiology. (2008) (0)
2010 Annual Anesthesiology/FAER Joint Session Call for Abstracts (2009) (0)
Fueling Discovery for Anesthesiology’s Future With $875,000 in New Grant Funding (2017) (0)
Peripheral nerve injury in rats induces alternations in choice behavior associated with food reinforcement (2019) (0)
Notes of a Medical Educator: Observations, Reflections, and Connections. (2000) (0)
Society of Neurosurgical Anesthesia and Critical Care: Annual Meeting Report. (2000) (0)
Room B, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Morphine-Induced Adenosine Release Is Reduced from Spinal Cord in Neuropathic Rats A-927 (2000) (0)
It's a bright and sunny day: Anesthesiology in 2011. (2011) (0)
Anesthesiology/FAER Session (2007) (0)
FAER … Find us at ANESTHESIOLOGY® 2019 (2019) (0)
Room B, 10/16/2000 2: 00 PM - 4: 00 PM (PS) No Difference in Cerebrospinal Fluid Pharmacokinetics of Intrathecally Administered Adenosine in Normal Versus Spinal Nerve Ligated Rats A-903 (2000) (0)
Early and delayed effects of intravenous administration of remifentanil and naloxone on sensitivity to thermal stimuli (2010) (0)
FAER … Helping us Foster the Future (2019) (0)
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2010 Annual Journal Symposium Call for Abstracts (2009) (0)
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A754 SITE OF INTRATHECAL CLONIDINE-INDUCED HYPOTENSION (1990) (0)
Intrathecal Neostigmine in a Rat Model of Postoperative Pain (1998) (0)
Differing Neurophysiologic Mechanosensory Input from 1 Glabrous and Hairy Skin in Juvenile Rats 2 3 (2010) (0)
FAER … and Physician Mentorship (2019) (0)
Is Chronic Pain After Childbirth Rare, and if so, Why Do We Care? (2010) (0)
Antihypersensitivity Effect of Intrathecal Clonidine in a Rat Model of Postoperative Pain: Both a2A and a2NON A Adrenoceptors Participate: [2002][A-862] (2002) (0)
A Postal Cover from Dr. R. N. Hudson: A Vocal Tenor and Vocal Nitrous Oxide Specialist. (2016) (0)
FAER … and Enhanced Recovery (2018) (0)
Gadgeteering for Pain Relief: The 2021 John W. Severinghaus Lecture on Translational Science. (2022) (0)
Anesthetic Management of the Elderly Measuring Function beyond the Immediate Perioperative (1999) (0)
In reply. (2014) (0)
A728 IV Morphine Produces Antinociception by a Spinal Action Involving Nitric Oxide (1997) (0)
(299) Down-regulation of astroglial glutamate transporters in the locus coeruleus contributes to impairment of endogenous analgesia in rats after peripheral nerve injury (2015) (0)
Interaction Between Spinal α2-adrenergic and Cholinergic Controls on Blood Pressure Regulation (1992) (0)
Retraction. Fospropofol assay issues and impact on pharmacokinetic and pharmacodynamic evaluation. (2010) (0)
DOES INTRATHECAL CLONIDINE RELEASE ACETYLCHOLINE (ACH) (1991) (0)
The number and function of spinal cholinergic interneurons regulate the antiallodynic effects of intrathecal clonidine in a rat neuropathic pain model (2000) (0)
Predicting pain after joint surgery (2013) (0)
Creation of the Anesthesia Research Council. (2020) (0)
Anesthesiology and the Japanese Society of Anesthesiologists: the science is amazing. (2010) (0)
Spinal Prostaglandins Modulate Pain from Uterine Cervical Distension: [2002][A-777] (2002) (0)
New Medical Knowledge: Practical for Practitioners, Transformational for Those We Treat (2016) (0)
Are Signposts in the Woods Pointing in the Right Direction (2009) (0)
Antisense oligodeoxynucleotide (ODN) demonstrates that clonidine analgesic effect is mediated by α2A adrenoceptors in rat spinal cord (2000) (0)
FAER Funding Helps Maintain Continuous Transformation (2016) (0)
Intrathecal oxytocin for neuropathic pain: A randomized, controlled, cross-over trial (2022) (0)
In Reply. (2016) (0)
β-2 adrenergic agonists (2018) (0)
Neostigmine as the Fourth Spinal Component for Labor Analgesia (2000) (0)
Long-term Consequences of Anesthetic Management (2015) (0)
Spinal clonidine and the response to hemorrhage (1990) (0)
No Difference in Cerebrospinal Fluid Pharmacokinetics of Intrathecally Administered Adenosine in Normal Versus Spinal Nerve Ligated Rats (2002) (0)
HEMODYNAMIC AND SPINAL CORD BLOOD FLOW EFFECTS OF EPIDURAL CLONIDINE IN SHEEP (1987) (0)
3 Modern epidural technques (1995) (0)
Upsetting the Apple Cart on the Path to Transformation (2016) (0)
Keeping Mom Awake: Does Placental Location Impact Fetal Disruption of Maternal Sleep? (2019) (0)
21st Annual Meeting of the American Society of Regional Anesthesia (1996) (0)
Interaction between Systemic Alfentanil and Amitriptyline on Pain from Intradermal Capsaicin in Volunteers (1997) (0)
Receptors and channels (2004) (0)
A Great Year Behind Us, and Even Better One Ahead (2017) (0)
Oestrogen decreases mu, but not kappa opioid antinociception in visceral pain (2002) (0)
A919 EPIDURAL CLONIDINE INFUSION FOLLOWING CESAREAN SECTION (1990) (0)
m REPORT OF SCIENTIFIC MEETING (2000) (0)
Effect of 2-Chloroprocaine Test Dosing on the Subsequent Duration of Labor Analgesia with Epidural Bupivacaine-Fentanyl-Epinephrine (1988) (0)
Impact of chronic nicotine on the development and maintenance of neuropathic pain in the rat (2005) (0)
A Randomized Controlled Trial Comparing 2 Multimodal Analgesic Techniques in Patients Predicted to Have Severe Pain After Cesarean Delivery (2016) (0)
Neurons and Neighboring Intact Dorsal Root Ganglion Similar Electrophysiological Changes in Axotomized (2015) (0)
Sex differences in anti-allodynic effects of cholinergic agonists in a model of neuropathic pain (1998) (0)
Potency and Efficacy of Clonidine and ST91 in Normal and in Spinal Nerve Ligated Rats: [2002][A-841] (2002) (0)
G-Proteins in Neuropathic Pain The Role of Adenosine (2002) (0)
SPINAL PROSTAGIANDINS MODULATE PAIN FROM UTERINE CERVICAL DISTENSION: P‐91 (2002) (0)
Basic Science (24) (2001) (0)
Introduction: Gaston Labat Award 2003: Brendan Thomas Finucane, M.B.BCh., B.A.O., F.R.C.P.C., F.R.C.A. (2003) (0)
FAER … Leaving a Legacy to Sustain the Future (2019) (0)
Creating Community in 2019: FAER’s Support for Medical Students and Residents (2019) (0)
Antinociceptive Interactions of Adenosine and Clonidine in a Rat Model of Acute Pain (1998) (0)
FAER … and Technology (2018) (0)
1) 0-substituted serine and threonine residues in acetylcholine receptor protein from Torpedo Californica 2) Synthesis of a new fluorescent probe for ligand binding to acetylcholine receptor from Torpedo Californica (1978) (0)
Anesthesiology, Its Mission, and 2007’s “Best” Articles (2008) (0)
Does Anesthesiology, Like History, Repeat Itself? (1998) (0)
Numb Toes and Aching Soles: Coping with Peripheral Neuropathy. (2000) (0)
Animal models of chronic pain: Adenosine A1 receptor activation inhibits allodynia caused by diabetic neuropathy or arthritis but ineffective for acute inflammatory visceral pain (2004) (0)
MECHANISM OF ANTIARRHYTHMIC EFFECT OF DEXMEDETOMIDINE ON EPINEPHRINE-INDUCED ARRTHYTHMIAS. AUTHOR'S REPLY (1991) (0)
Intravenous Clonidine Hydrochloride Toxicity in Pregnant Ewes (1989) (0)
Room 301, 10/18/2000 2: 00 PM - 3: 30 PM (PD) Intrathecal Adenosine Reduces the Areas of Hyperalgesia and Allodynia Which Follow Intradermal Capsaicin in Volunteers A-1001 (2000) (0)
Polymodal Pelvic Nerve Afferent Fibers in the Rat Effects of Intracolonic Opioid Receptor Agonists on (2015) (0)
Anesthesiology: the Best New Science in the Specialty (2015) (0)
FAER…..and The Importance of Giving (2018) (0)
Peripheral Nerve Injury Alters the (cid:1) 2 Adrenoceptor Subtype Activated by Clonidine for Analgesia (2002) (0)
Transforming Anesthesiology: How the Specialty Can Become a Vibrant Contributor to Improve Public Health and Patient Safety (2016) (0)
Nitric Oxide Mediates the Protective Effect of Ephedrine on Uterine Blood Flow (1994) (0)
FAER … and Obstetric Anesthesiology Research (2019) (0)
Reply: Central Cholinergic Stimulation Causes Miosis (1995) (0)
VASOPRESSIN AND FETAL CEREBRAL BLOOD FLOW DURING HYPOXEMIA (1989) (0)
FAER ‘Swimming With Sharks’ to Buoy Entrepreneurs This October (2017) (0)
New drugs for central neuraxis blockade (1990) (0)
Plasma and Cerebrospinal(CSF) Fluid Pharmacokinetics Following Intrathecal, Epidural, and Intravenous Clonidine Administration in Sheep (1988) (0)
OUTCOMES RESEARCH (2000) (0)
The Role of Medical Societies and Their Foundations in Supporting Entrepreneurs: A View From Anesthesiology (2018) (0)
289) The effects of nerve injury on the expression of vasopressin receptor V1aR in the dorsal root ganglia (2014) (0)
Atlas of Anesthesia Volume VII: Pediatric Anesthesia. (2000) (0)
Anti-allodynic effects of an American formulation of adenosine (1998) (0)
Educational Material (2020) (0)
The FAER Report (2017) (0)
Sex mterences in Cholinergic Analgesia A Supplemental Nicotinic Mechanism in Normal Females (2006) (0)
Interaction Between Spinal a2 Adrenergic and Cholinergic Controls on Blood Pressure Regulation (1992) (0)
Pulse Oximetry in the Postanesthetic Care Unit (2006) (0)
FAER … and ANESTHESIOLOGY® 2018 (2018) (0)
Annual Journal Symposium (2007) (0)
Spinal Nerve Ligation in Monkey 6 -Adrenergic Sensitivity Following L α Activity and Uninjured C-Fiber Nociceptors Develop Spontaneous (2015) (0)
Safety of Adenosine in Rats for Intrathecal Administration (1998) (0)
Peripheral Nerve Injury Alters the a2-Adrenoceptor Subtype Activated by Clonidine for Analgesia: [2002][A-1372] (2002) (0)
FAER ...Celebrating Different Perspectives (2019) (0)
FAER and OthersThanks for 25 Years of Doing More than Funding Research (2011) (0)
Why is Karolinska on the cover of an American journal? (2010) (0)
Call for Candidates for 2010 Presidential Scholar Award (2009) (0)
Professionalism in Anesthesiology “ What Is It ? ” or “ I Know It When I See It ” (2009) (0)
Finding and getting what you want when you want it just got easier at ANESTHESIOLOGY. (2015) (0)
FAER … A Dozen People Who Might Change the Opioid Crisis (2020) (0)
Antinociceptive and Hernodynarnic Eflects of a Novel cu,-Adrenergic Agonist, MPV-2426; in Sheep (2006) (0)
Anesthesiology Pocket Guide. (2000) (0)
m REVIEWS OF EDUCATIONAL MATERIAL (2017) (0)
Nominations Sought for 2015 ASA Award for Excellence in Research (2011) (0)
Announcement and Call for Abstracts and Papers: 2015 Annual Journal Symposium (2015) (0)
The Need for Perspective (2009) (0)
Gabapentin enhances glutamate-induced glutamate release from cultured astrocytes (2019) (0)
In reply. (2014) (0)
Optimization of a Method to Simultaneously Measure Excitation and Inhibition of Populations of Dorsal Root Ganglion Neurons: Effect of Morphine and Norepinephrine: [2002][A-840] (2002) (0)
Preclinical postoperative pain trajectories: impact of experimental predictors on recovery (2021) (0)
Joint, muscle, and visceral pain (2004) (0)
Nominations Sought for Award for Excellence in Research (2009) (0)
Collaboration, Advocacy, and the ARC (2021) (0)

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