James C. Hogg

Q: What Schools Are Affiliated With James C. Hogg

James C. Hogg is affiliated with the following schools: Harvard University, Nanjing Normal University, Massey University, McGill University, University of British Columbia, Toronto Metropolitan University, University of Manitoba, Massachusetts General Hospital

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James C. Hogg

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Philosophy

James C. Hogg's Degrees

Doctorate Medicine Harvard University

Why Is James C. Hogg Influential?

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According to Wikipedia, James C. Hogg is a Canadian physician and one of Canada's leading pulmonary pathologists. Hogg has been recognized for his research into Chronic Obstructive Pulmonary Disease. He received the Canada Gairdner Wightman Award in 2013. He became an officer of the Order of Canada in 2005 and was named to the Canadian Medical Hall of Fame in 2010. He also received the Queen Elizabeth II’s Diamond Jubilee Medal.

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James C. Hogg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors (2002) (3524)
The nature of small-airway obstruction in chronic obstructive pulmonary disease. (2004) (3497)
Site and nature of airway obstruction in chronic obstructive lung disease. (1968) (1312)
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease (2004) (1188)
Decreased histone deacetylase activity in chronic obstructive pulmonary disease. (2005) (972)
The mechanics of airway narrowing in asthma. (1989) (830)
The relations between structural changes in small airways and pulmonary-function tests. (1978) (808)
Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. (2000) (689)
Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)). (2001) (688)
Small airways dimensions in asthma and in chronic obstructive pulmonary disease. (1993) (620)
Mechanics of airway narrowing. (2015) (606)
Particulate air pollution induces progression of atherosclerosis. (2002) (583)
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. (2011) (555)
Inflammation of small airways in asthma. (1997) (549)
Amplification of inflammation in emphysema and its association with latent adenoviral infection. (2001) (544)
Functional significance of increased airway smooth muscle in asthma and COPD. (1993) (517)
A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. (1992) (478)
The lung tissue microbiome in chronic obstructive pulmonary disease. (2012) (463)
The prediction of small airway dimensions using computed tomography. (2005) (413)
The pathology of chronic obstructive pulmonary disease. (2009) (392)
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. (2008) (388)
A quantification of the lung surface area in emphysema using computed tomography. (1999) (370)
CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society. (2015) (369)
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. (2004) (330)
Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. (2003) (315)
Sex differences in severe pulmonary emphysema. (2007) (315)
The diagnosis of emphysema. A computed tomographic-pathologic correlation. (1986) (309)
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease. (2010) (309)
Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung. (1993) (301)
Neutrophil kinetics and lung injury. (1987) (300)
Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma (2012) (300)
The effect of cigarette smoking on neutrophil kinetics in human lungs. (1989) (300)
The stability of peripheral airways. (1970) (291)
The human bone marrow response to acute air pollution caused by forest fires. (2000) (277)
Particulate matter induces cytokine expression in human bronchial epithelial cells. (2001) (261)
Leukocyte traffic in the lung. (1995) (253)
Small airway dimensions in smokers with obstruction to airflow. (1990) (253)
Characterization of airway plugging in fatal asthma. (2003) (250)
Age as a factor in the distribution of lower-airway conductance and in the pathologic anatomy of obstructive lung disease. (1970) (247)
Latent adenoviral infection in the pathogenesis of chronic airways obstruction. (1992) (245)
The use of the internal perimeter to compare airway size and to calculate smooth muscle shortening. (1988) (241)
Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease. (2016) (237)
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase‐9 (2009) (230)
Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease. (2019) (230)
Penetration of the respiratory epithelium of guinea pigs following exposure to cigarette smoke. (1974) (226)
Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry. (1992) (223)
Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization. (2004) (223)
Reassessment of inflammation of airways in chronic bronchitis. (1985) (221)
A model of the mechanics of airway narrowing. (1990) (218)
Hyperpolarized 3He diffusion MRI and histology in pulmonary emphysema (2006) (215)
Glucocorticoid-induced granulocytosis: contribution of marrow release and demargination of intravascular granulocytes. (1998) (215)
Pulmonary vascular structure and function in chronic obstructive pulmonary disease. (1988) (210)
Interaction of alveolar macrophages and airway epithelial cells following exposure to particulate matter produces mediators that stimulate the bone marrow. (2002) (203)
Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells. (1999) (201)
Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. (2004) (201)
Contribution of emphysema and small airways in COPD. (1996) (197)
Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology. (2007) (195)
Morphology of peripheral airways in current smokers and ex-smokers. (2015) (195)
The use of flow cytometry to measure neutrophil function. (1999) (192)
Proposed nomenclature for quantifying subdivisions of the bronchial wall. (1994) (190)
Systemic response to ambient particulate matter: relevance to chronic obstructive pulmonary disease. (2005) (189)
The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research. (2007) (188)
Report of a workshop: quantitative computed tomography scanning in longitudinal studies of emphysema (2004) (187)
Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. (2015) (183)
Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study. (2018) (180)
Emphysematous lung destruction by cigarette smoke. The effects of latent adenoviral infection on the lung inflammatory response. (2002) (175)
A comparison of bronchiolitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airways disease. (2015) (171)
The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease. (2017) (170)
The response of human bone marrow to chronic cigarette smoking. (2000) (169)
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. (2008) (169)
Interleukin-6 induces demargination of intravascular neutrophils and shortens their transit in marrow. (2000) (166)
Quantification of lung microstructure with hyperpolarized 3He diffusion MRI. (2009) (165)
Marginated pool of neutrophils in rabbit lungs. (1987) (165)
Proteoglycan deposition in pulmonary fibrosis. (1996) (162)
Airway permeability to horseradish peroxidase in guinea pigs: the repair phase after injury by cigarette smoke. (2015) (162)
The effect of repeated exposure to particulate air pollution (PM10) on the bone marrow. (2001) (160)
Role of latent viral infections in chronic obstructive pulmonary disease and asthma. (2001) (160)
Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study (2015) (154)
Chronic obstructive pulmonary disease c 2: Pathology and biochemistry of emphysema (2002) (152)
The detection of small airways disease. (1984) (149)
Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease. (2010) (147)
The resistance of collateral channels in excised human lungs. (1969) (142)
Phagocytosis of small carbon particles (PM10) by alveolar macrophages stimulates the release of polymorphonuclear leukocytes from bone marrow. (1997) (141)
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung. (1994) (139)
Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment (2005) (138)
Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma. (2000) (138)
Distribution of airway resistance with developing pulmonary edema in dogs. (1972) (138)
Differential diagnosis of bronchiolitis obliterans with organizing pneumonia and usual interstitial pneumonia: clinical, functional, and radiologic findings. (1987) (137)
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. (2013) (136)
Cartilaginous airway dimensions and airflow obstruction in human lungs. (1995) (135)
SYSTEMIC INFLAMMATORY RESPONSE INDUCED BY PARTICULATE MATTER AIR POLLUTION: THE IMPORTANCE OF BONE-MARROW STIMULATION (2002) (134)
Transforming growth factor beta 1 gene expression in human airways. (1994) (132)
The structure and function of the pulmonary vasculature in mild chronic obstructive pulmonary disease. The effect of oxygen and exercise. (1983) (131)
The effect of cigarette smoke on the permeability of guinea pig airways. (1980) (129)
The effects of radiation dose and CT manufacturer on measurements of lung densitometry. (2007) (128)
Circulating hematopoietic progenitor cells in runners. (2002) (126)
Small airway obstruction in COPD: new insights based on micro-CT imaging and MRI imaging. (2013) (125)
Limited contribution of emphysema in advanced chronic obstructive pulmonary disease. (1993) (125)
Measurement of lung expansion with computed tomography and comparison with quantitative histology. (1995) (123)
Changes in the Bacterial Microbiota in Gut, Blood, and Lungs following Acute LPS Instillation into Mice Lungs (2014) (121)
Particulate matter air pollution stimulates monocyte release from the bone marrow. (2004) (120)
Molecular signature of smoking in human lung tissues. (2012) (120)
Eotaxin and monocyte chemotactic protein-4 mRNA expression in small airways of asthmatic and nonasthmatic individuals. (1999) (119)
Bronchial mucosal permeability and its relationship to airways hyperreactivity. (1981) (118)
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK (2012) (117)
Contributions of capillary pathway size and neutrophil deformability to neutrophil transit through rabbit lungs. (1994) (114)
Leukocytosis of exercise: role of cardiac output and catecholamines. (1986) (112)
Bacterial microbiome of lungs in COPD (2014) (112)
Structure of central airways in current smokers and ex-smokers with and without mucus hypersecretion: relationship to lung function. (1987) (112)
Effects of CT section thickness and reconstruction kernel on emphysema quantification relationship to the magnitude of the CT emphysema index. (2010) (112)
Nitric oxide reduces the sequestration of polymorphonuclear leukocytes in lung by changing deformability and CD18 expression. (1999) (111)
Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population‐based Study (2018) (109)
Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries. (1994) (107)
Lung structure and function in cigarette smokers. (1994) (106)
Release of polymorphonuclear leukocytes from the bone marrow by interleukin-8. (1998) (106)
Cytokine mRNA expression in asthma is not restricted to the large airways. (1998) (104)
Effect of histamine and methacholine on guinea pig tracheal permeability to HRP. (1978) (99)
Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease. (2010) (98)
Childhood viral infection and the pathogenesis of asthma and chronic obstructive lung disease. (1999) (98)
Polymorphonuclear leukocyte transit times in bone marrow during streptococcal pneumonia. (1996) (98)
Contribution of IL-1β and TNF-α to the initiation of the peripheral lung response to atmospheric particulates (PM10) (2004) (98)
A non-radioisotopic method for tracing neutrophils in vivo using 5'-bromo-2'-deoxyuridine. (1994) (97)
Respiratory mucosal permeability in asthma. (1983) (96)
Is asthma an epithelial disease? (1984) (95)
Polymorphonuclear Leukocytes Released from the Bone Marrow Preferentially Sequester in Lung Microvessels (1997) (93)
The comparative mechanics and morphology of airways in asthma and in chronic obstructive pulmonary disease. (1991) (93)
Quantification of idiopathic pulmonary fibrosis using computed tomography and histology. (1997) (93)
Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8. (2001) (93)
Particulate matter air pollution exposure promotes recruitment of monocytes into atherosclerotic plaques. (2008) (92)
Convergence of the epidemiology and pathology of COPD (2005) (92)
Erythrocyte transit and neutrophil concentration in the dog lung. (1988) (91)
Leukocyte kinetics in the human lung: role of exercise and catecholamines. (1984) (91)
Effect of pulmonary blood flow on the exchange between the circulating and marginating pool of polymorphonuclear leukocytes in dog lungs. (1982) (91)
Persistence of respiratory syncytial virus genome and protein after acute bronchiolitis in guinea pigs. (1994) (90)
Phagocytosis of particulate air pollutants by human alveolar macrophages stimulates the bone marrow. (2000) (89)
Preoperative severity of emphysema predictive of improvement after lung volume reduction surgery: use of CT morphometry. (2000) (89)
Prediction of the rate of decline in FEV1 in smokers using quantitative computed tomography (2009) (88)
Pseudophysiologic emphysema resulting from severe small-airways disease. (1998) (88)
Pulmonary and systemic response to atmospheric pollution (2009) (88)
Effect of vagal stimulation on central and peripheral airways in dogs. (1969) (86)
Transcriptional regulatory model of fibrosis progression in the human lung. (2019) (86)
The effect of acute airway inflammation on bronchial reactivity in guinea pigs. (1985) (86)
Cigarette smoking causes sequestration of polymorphonuclear leukocytes released from the bone marrow in lung microvessels. (1999) (86)
Adenovirus E1A upregulates interleukin-8 expression induced by endotoxin in pulmonary epithelial cells. (1997) (85)
Increased airway mucosal permeability of smokers. Relationship to airway reactivity. (1984) (84)
Redistribution of pulmonary extravascular water with positive end-expiratory pressure in canine pulmonary edema. (2015) (83)
Respiratory epithelial permeability after cigarette smoke exposure in guinea pigs. (1989) (81)
A comparison of in vivo and in vitro human airway reactivity to histamine. (2015) (81)
Thurlbeck's Pathology of the Lung (2005) (81)
The site and nature of airway obstruction after lung transplantation. (2014) (80)
Persistent pneumocystis colonization leads to the development of chronic obstructive pulmonary disease in a nonhuman primate model of AIDS. (2010) (80)
COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. (2019) (80)
The effect of glucocorticoids on the expression of L-selectin on polymorphonuclear leukocyte. (1999) (80)
Experimental papain-induced emphysema in dogs. (1970) (79)
The effect of cigarette smoking on the bone marrow. (1997) (79)
Nonspecific airway reactivity in cigarette smokers. Relationship to airway pathology and baseline lung function. (2015) (78)
Interleukin-6 changes deformability of neutrophils and induces their sequestration in the lung. (2001) (78)
Relationship between airway hyperreactivity and hyperpermeability in Ascaris-sensitive monkeys. (1979) (78)
Core to rind distribution of severe emphysema predicts outcome of lung volume reduction surgery. (2001) (78)
Long-range diffusion of hyperpolarized 3He in explanted normal and emphysematous human lungs via magnetization tagging. (2005) (78)
Elastic properties of the centrilobular emphysematous space. (1969) (77)
Elastin expression in very severe human COPD (2009) (77)
Adenovirus infections and lung disease (2007) (76)
The effect of submucosal edema on airways resistance. (2015) (76)
Selection of patients for lung volume reduction surgery using a power law analysis of the computed tomographic scan (2003) (76)
Freeze-etch study of the tracheal epithelium of normal guinea pigs with particular reference to intercellular junctions. (1977) (76)
Expression of the cell adhesion molecules on leukocytes that demarginate during acute maximal exercise. (1999) (75)
Extracellular matrix remodeling of lung alveolar walls in three dimensional space identified using second harmonic generation and multiphoton excitation fluorescence. (2010) (75)
Immunodetection of adenoviral E1A proteins in human lung tissue. (1995) (75)
Neutrophil kinetics in rabbits during infusion of zymosan-activated plasma. (1989) (74)
Detection of Epstein-Barr virus in lymphocytic interstitial pneumonia by in situ hybridization. (1992) (73)
The changes in airways structure associated with reduced forced expiratory volume in one second. (1989) (73)
The effect of latent adenovirus 5 infection on cigarette smoke-induced lung inflammation. (1998) (73)
Exponential analysis of the lung pressure-volume curve as a predictor of pulmonary emphysema. (2015) (73)
Effects of lung volume, bronchoconstriction, and cigarette smoke on morphometric airway dimensions. (1988) (72)
Molecular mechanisms underlying variations in lung function: a systems genetics analysis. (2015) (71)
The Role of Chest Computed Tomography in the Evaluation and Management of the Patient with Chronic Obstructive Pulmonary Disease (2017) (71)
Vascularity in asthmatic airways: relation to inhaled steroid dose (1999) (70)
Refining Susceptibility Loci of Chronic Obstructive Pulmonary Disease with Lung eqtls (2013) (70)
Alveolar epithelial damage. A critical difference between high pressure and oleic acid-induced low pressure pulmonary edema. (1986) (69)
Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory tract infections. (1995) (68)
miR-638 regulates gene expression networks associated with emphysematous lung destruction (2013) (68)
The effect of body temperature on leukocyte kinetics during cardiopulmonary bypass. (1985) (67)
The association between small airway obstruction and emphysema phenotypes in COPD. (2007) (67)
Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease (2019) (67)
The pathology of asthma (1984) (67)
Leukocyte and platelet margination within microvasculature of rabbit lungs. (1990) (66)
Why does airway inflammation persist after the smoking stops? (2006) (66)
The Relationship Between Respiratory Viral Loads and Diagnosis in Children Presenting to a Pediatric Hospital Emergency Department (2011) (66)
Exposure to ambient particles accelerates monocyte release from bone marrow in atherosclerotic rabbits. (2004) (66)
Contribution of IL-1 beta and TNF-alpha to the initiation of the peripheral lung response to atmospheric particulates (PM10). (2004) (65)
Atypical Activation of the Unfolded Protein Response in Cystic Fibrosis Airway Cells Contributes to p38 MAPK-Mediated Innate Immune Responses (2012) (65)
Polymorphonuclear leukocyte (PMN) migration in streptococcal pneumonia: comparison of older PMN with those recently released from the marrow. (1996) (64)
L-selectin expression increases on peripheral blood polymorphonuclear leukocytes during active marrow release. (1995) (63)
The pathology of asthma. (1993) (63)
Bronchopulmonary dysplasia in the adult. (2015) (62)
Conference report of a workshop on the measurement of lung water (1980) (62)
What drives the peripheral lung-remodeling process in chronic obstructive pulmonary disease? (2009) (62)
Inflammatory mediator mRNA expression by adenovirus E1A-transfected bronchial epithelial cells. (2002) (61)
Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology (2018) (61)
TRANSIENT LEUCOPENIA ASSOCIATED WITH ADULT RESPIRATORY DISTRESS SYNDROME (1984) (61)
Effect of breathing dry air on structure and function of airways. (1986) (61)
Quantitation of neutrophil migration in acute bacterial pneumonia in rabbits. (1994) (60)
Adenovirus E1A gene dysregulates ICAM-1 expression in transformed pulmonary epithelial cells. (1997) (60)
The number and distribution of mast cells in monkey lungs. (1979) (60)
Regional lung volume and pleural pressure gradient estimated from lung density in dogs. (1969) (59)
Activation of neutrophils within pulmonary microvessels of rabbits exposed to cigarette smoke. (1993) (57)
A Comparison between Droplet Digital and Quantitative PCR in the Analysis of Bacterial 16S Load in Lung Tissue Samples from Control and COPD GOLD 2 (2014) (57)
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro. (1985) (57)
Micro-computed tomography measurements of peripheral lung pathology in chronic obstructive pulmonary disease. (2009) (56)
Airway mucosal permeability in the Ascaris suum-sensitive rhesus monkey. (1977) (56)
Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study (2016) (56)
In vivo lung morphometry with hyperpolarized 3He diffusion MRI in canines with induced emphysema: disease progression and comparison with computed tomography. (2007) (56)
Thin-Section CT Features of Idiopathic Pulmonary Fibrosis Correlated with Micro-CT and Histologic Analysis. (2017) (56)
A novel method to quantify the turnover and release of monocytes from the bone marrow using the thymidine analog 5'-bromo-2'-deoxyuridine. (2003) (55)
Partitioning of pulmonary resistance in the dog. (1969) (55)
Latent adenoviral infection modifies the steroid response in allergic lung inflammation. (2000) (55)
Three Dimensional Imaging of Paraffin Embedded Human Lung Tissue Samples by Micro-Computed Tomography (2015) (55)
Influence of autonomic nervous system on airway resistance and elastic recoil. (1969) (54)
Mast cell infiltration discriminates between histopathological phenotypes of chronic obstructive pulmonary disease. (2012) (53)
Proteoglycans in granulomatous lung diseases. (1997) (52)
Localization of antigen in experimental bronchoconstriction in guinea pigs. (1973) (52)
Computed tomographic estimation of lung dimensions throughout the growth period (2006) (51)
Histamine dose-response curves in guinea pigs. (1985) (51)
A morphologic grading scheme for membranous and respiratory bronchioles. (1985) (51)
Linking clinical phenotypes of chronic lung allograft dysfunction to changes in lung structure (2015) (51)
Morphologic determinants of airway responsiveness in chronic smokers. (1996) (50)
Complement fragment-induced release of neutrophils from bone marrow and sequestration within pulmonary capillaries in rabbits. (1998) (49)
Mechanisms of maximal expiratory flow limitation in clinically unsuspected emphysema and obstruction of the peripheral airways. (2015) (49)
Regional pulmonary transit times in humans. (1989) (49)
Myocardial morphometric changes related to decreased contractility after endotoxin. (1996) (49)
Bacteremic pneumococcal pneumonia: bone marrow release and pulmonary sequestration of neutrophils. (1998) (49)
Prolonged leukocyte transit time in coronary microcirculation of endotoxemic pigs. (1995) (49)
Micro‐Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema (2017) (48)
Regional differences in neutrophil margination in dog lungs. (1987) (47)
Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction. (1994) (47)
Bronchopulmonary anastomotic and noncoronary collateral blood flow in humans during cardiopulmonary bypass. (1985) (46)
Occupational exposure to hydrocarbons and chronic pancreatitis: a case-referent study. (1994) (46)
Production of acute bronchiolitis in guinea-pigs by human respiratory syncytial virus. (1993) (46)
Morphometric Analysis of Explant Lungs in Cystic Fibrosis. (2016) (46)
Effect of pulmonary blood flow on leukocyte uptake and release by dog lung. (1984) (45)
Chronic obstructive pulmonary disease: an overview of pathology and pathogenesis. (2008) (45)
A re-assessment of the tricellular region of epithelial cell tight junctions in trachea of guinea pig. (1985) (45)
Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study. (2020) (45)
Quantitative measurement of smooth muscle shortening in isolated pig trachea. (1987) (44)
Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function. (2018) (44)
In situ hybridization studies of adenoviral infections of the lung and their relationship to follicular bronchiectasis. (1989) (44)
Estimation of lung growth using computed tomography (2003) (43)
Polymorphonuclear leukocytes L-selectin expression decreases as they age in circulation. (1997) (43)
Monocyte recruitment into the lungs in pneumococcal pneumonia. (2004) (43)
The expression of adhesion molecules in cigarette smoke-induced airways obstruction. (1996) (42)
A model of latent adenovirus 5 infection in the guinea pig (Cavia porcellus). (1996) (42)
Latent adenoviral infection induces production of growth factors relevant to airway remodeling in COPD. (2004) (41)
Functional changes in aging polymorphonuclear leukocytes. (1998) (41)
The cellular and molecular determinants of emphysematous destruction in COPD (2017) (41)
Intercellular junctions of the tracheal epithelium in guinea pigs. (1974) (41)
BAL induces an increase in peripheral blood neutrophils and cytokine levels in healthy volunteers and patients with pneumonia. (2001) (40)
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis (2018) (39)
Endothelin-1 changes polymorphonuclear leukocytes' deformability and CD11b expression and promotes their retention in the lung. (2000) (39)
The effect of interleukin-6 on L-selectin levels on polymorphonuclear leukocytes. (2002) (38)
Neutrophil kinetics during active cigarette smoking in rabbits. (1991) (38)
A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography (2017) (38)
The Immunopathogenesis of Chronic Obstructive Pulmonary Disease (2012) (38)
Zonulae occludentes in alveolar epithelium and capillary endothelium of dog lungs studies with the freeze-fracture technique. (1976) (38)
Impact of Cigarette Smoke on the Human and Mouse Lungs: A Gene-Expression Comparison Study (2014) (38)
Endotoxin-specific NF-κB activation in pulmonary epithelial cells harboring adenovirus E1A. (1999) (37)
Distribution of blood flow in the lungs in acute pulmonary edema in dogs. (1972) (37)
Effects of diffusion time on short‐range hyperpolarized 3He diffusivity measurements in emphysema (2009) (36)
Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation. (2002) (35)
Expression of bcl-2 and Epstein-Barr virus LMP1 in lymphocytic interstitial pneumonia. (1997) (35)
Effect of regional lung expansion and body position on pulmonary perfusion in dogs. (1971) (35)
Effect of raised alveolar pressure on leukocyte retention in the human lung. (1990) (35)
Evidence for inflammation in asthma. (1991) (34)
Lung structure and function in COPD. (2008) (34)
Effect of positive end-expiratory pressure on leukocyte transit in rabbit lungs. (1993) (33)
Pulmonary 'mainline' granulomatosis: talcosis of intravenous methadone abuse. (1979) (33)
The aging lung: tissue telomere shortening in health and disease (2018) (33)
Airway responses to histamine and methocholine in Ascaris suum-allergic rhesus monkeys. (1978) (33)
Apoptosis in circulating PMN: increased susceptibility in L-selectin-deficient PMN. (1997) (32)
Polymorphonuclear leucocyte traffic in lung inflammation. (1995) (32)
Peripheral lung remodelling in asthma and chronic obstructive pulmonary disease (2004) (32)
Airway responsiveness to intravenous and inhaled acetylcholine in the guinea pig after cigarette smoke exposure. (1987) (32)
Polymorphonuclear leukocytes released from the bone marrow and acute lung injury. (1999) (31)
Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction (2014) (31)
Neutrophil retention during a single transit through the pulmonary circulation. (1992) (31)
PCR detection of viral nucleic acid in fatal asthma: is the lower respiratory tract a reservoir for common viruses? (1999) (31)
Association between Functional Small Airway Disease and FEV 1 Decline in Chronic Obstructive Pulmonary Disease (2016) (31)
A Lung Tissue Bank for Gene Expression Studies in Chronic Obstructive Pulmonary Disease (2004) (31)
Exponential analysis of the pressure-volume curve. Correlation with mean linear intercept and emphysema in human lungs. (1988) (30)
Integrative Genomics of Emphysema‐Associated Genes Reveals Potential Disease Biomarkers (2017) (30)
Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue. (2017) (30)
Latent adenoviral infection in follicular bronchiectasis. (1995) (30)
Leukocyte activation does not mediate myocardial leukocyte retention during endotoxemia in rabbits. (1998) (29)
L-selectin expression on polymorphonuclear leukocytes and monocytes in premature infants: reduced expression after dexamethasone treatment for bronchopulmonary dysplasia. (1998) (29)
A possible role for CD8+ and non‐CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema (2013) (29)
A possible role for L-selectin in the release of polymorphonuclear leukocytes from bone marrow. (1997) (29)
Lung mechanics following antigen challenge of Ascaris suum-sensitive rhesus monkeys. (1976) (28)
Pulmonary effects of acute and chronic antigen exposure of immunized guinea pigs. (1979) (28)
Physiology and morphology of pulmonary microvascular injury with shock and reinfusion. (1981) (28)
Amplification of human beta-actin gene by the reverse transcriptase-polymerase chain reaction: implications for assessment of RNA from formalin-fixed, paraffin-embedded material. (1996) (28)
A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis (2018) (28)
Pulmonary sequestration of polymorphonuclear leukocytes released from bone marrow in bacteremic infection. (1998) (27)
Bronchial mucosal permeability. (1979) (27)
Regional distribution of extravascular water and hematocrit in the lung. (1979) (27)
Regional differences in erythrocyte transit in normal lungs. (1985) (27)
Asymmetry of canine tracheal epithelium: osmotically induced changes. (1984) (26)
AMBIENT AIR PARTICULATES STIMULATE ALVEOLAR MACROPHAGES OF SMOKERS TO PROMOTE DIFFERENTIATION OF MYELOID PRECURSOR CELLS (2002) (26)
Quantification of lung surface area using computed tomography (2010) (26)
Platelet-derived growth factor in bronchiolitis obliterans-organizing pneumonia. (1997) (26)
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Characterization Of Bronchus-associated Lymphoid Tissue (BALT) And Small Airway Pathology In A Non-human Primate Model Of HIV-associated COPD (2010) (0)
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Macrophage Polarization During Centrilobular Emphysematous Destruction In COPD (2011) (0)
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Direct Imaging Of Collagen And Elastin Structures In Inflated Frozen Human Lung Specimens At -60OC Using Harmonic Generation And Multiphoton Microscopy (2012) (0)
Alterations In Gene Expression With The Progression Of Airway And Emphysematous Components Of COPD (2011) (0)
Contributes to p 38 MAPK-Mediated Innate Response in Cystic Fibrosis Airway Cells Atypical Activation of the Unfolded Protein (2012) (0)
Stereological Analysis Of The Peripheral Lung Anatomy In Patients With Alpha-1 Antitrypsin Deficiency Using Mdct And Micro-CT (2015) (0)
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Spatial Dependence of Computed Tomography Emphysema in Chronic Obstructive Pulmonary Disease Quantified Using Join Count Statistics (2021) (0)
Alterations In Gene And MicroRNA Expression In The Lung Tissue Of Smokers With Chronic Obstructive Pulmonary Disease (2010) (0)
Cholinergic Receptor Nicotinic Alpha 5 Expression in the Airways of Patients with Chronic Obstructive Pulmonary Disease (2019) (0)
Quantification of Gas Trapping "Compactness" on Computed Tomography Is Associated With Clinically Relevant Outcomes in COPD (2023) (0)
Remodeling of Small Airways and Associated Arterial Vasculature Is a Hallmark of Idiopathic Pulmonary Fibrosis (2023) (0)
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Machine Learning for Predicting Health Care Utilization in COPD using Quantitative CT Imaging (2020) (0)
Chairman's Summary (1988) (0)
MacrophageAccumulationof Inhaled Gallium-67Citratein Normal Lungs (1985) (0)
The Role of Granzyme B in the Pathogenesis of COPD. (2009) (0)
Respiratory Viral Co-Infections In COPD: The "Dominant Virus" Paradigm (2011) (0)
Pressure volume characteristics in excised primate lungs and lobes (1975) (0)
Spatial Expression Quantitative Trait DNA Methylation Analysis of the Chronic Obstructive Pulmonary Disease Lung (2020) (0)
Airway Epithelial Gene Expression Patterns Associated With COPD Describe Potential Molecular Phenotypes Of Disease (2011) (0)
The treatment of mastoiditis and its complications. (1948) (0)
The Association Between Blood Eosinophils Counts and Decline in FEV1: Results from the CanCOLD Longitudinal Study (2019) (0)
Boxplots of gene expression levels in the lung for HHIP according to genotype groups for SNP rs1828591. (2013) (0)
Computed Tomography Emphysema and Small Airway Disease Progression Patterns in Chronic Obstructive Pulmonary Disease (2021) (0)
Reply to: Small Airways in Pulmonary Fibrosis: Revisiting an Old Question with New Tools. (2022) (0)
Reply to Hu et al.: How to Determine the Patient's Head and Neck Posture during Computed Tomography Scanning? (2018) (0)
The Effects of Diesel Exhaust Particles (DEP) on the Release of TNF-α and IL-6 from Alveolar Macrophages (1998) (0)
COPD_A_285338 305..320 (2021) (0)
Principal Component Analysis of Quantitative Computed Tomography Features and Visual Emphysema Scores: Association with Lung Function (0)
Small Airways Disease in COPD (2005) (0)
Development of CT texture analysis in COPD and association with visual scoring and DLCO (0)
Canadian contributions to pulmonary anatomy and pathology. (2007) (0)
Role of sinusitis in bronchiectasis. (1950) (0)
The influence of air ecology on human health (2000) (0)
Inspiration-Expiration CT Texture-Based Delta Radiomics: A New Biomarker Associated With COPD Symptoms? (2023) (0)
Effect of microspheres on pulmonary circulation with leukotriene C/sub 4/ (LTC/sub 4/) and histamine (HIS) (1986) (0)
Regional Red Blood Cell Transit Times in Human Lungs (1987) (0)
Boeck's Sarcoidosis with Nasal Lesion. (1946) (0)
Morphometrics and Mucosal Immune Features in Lungs With End-stage Chronic Obstructive Pulmonary Disease (2023) (0)
Effects of Acute Lobar Atclectasis on Pulmonary Hemodynamics (1972) (0)
Relationship to Disease States (1989) (0)
Microscopic Validation of Deep Learning Based Texture Classification of Idiopathic Pulmonary Fibrosis Patterns Visible on Thoracic Computed Tomography (2023) (0)
Bronchial asthma. (1978) (0)
Reactivity in Guinea Pigs 1 - 3 (1985) (0)
Decreased L-Selectin Expression on Polymorphonuclear Leucocytes Following Dexamethasone Treatment: Another Possible Anti-Inflammatory Mechanism (1997) (0)
Cryo-imaging of Inflated Frozen Human Lung Sections at -60°C using Multiphoton and Harmonic Generation Microscopy (2014) (0)
The pathophysiology of asthma. (1982) (0)
The transition from normal lung anatomy to Fibrosis in IPF (2019) (0)
A Role For Epigenetics in Cardiovascular (2013) (0)
Experimental pulmonary arteritis. (1980) (0)
Texture-based Computed Tomography Radiomics With Machine Learning Improves Predicting Chronic Obstructive Pulmonary Disease Outcomes (2023) (0)
A Preliminary Assessment Of Fungi In The Lung Microbiome (2012) (0)
Identification of New Molecular Pathways Involved in the Pathogenesis of Chronic Obstructive Pulmonary Disease by Proteomics Approaches (2012) (0)
Noninvasive Imaging Biomarker Identi ﬁ es Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease : Small Airway Imaging Biomarker in COPD (2019) (0)
Assessment of Small Airway Morphology Using Micro-Computed Tomography in Patients with Interstitial Lung Disease (2020) (0)
Pulmonary microcirculation: structure. (1982) (0)
PP-925 Endothelin-1(ET-1)のpolymorphonuclear leukocytes(PMN)機能・肺への集積への影響 (2000) (0)
Evidence for elastic fiber repair in emphysema (2006) (0)
Primary Pulmonary Hypertenslon (2017) (0)
Differential DNA Methylation and Aging Patterns According to Regional COPD Severity in Lung Tissue (2019) (0)
Deformabejty of younger polymorphonuclear leukocytes (PMN) released from the bone marrow (1996) (0)
The Heterogeneity of Prevalence and Risk Factors for Chronic Obstructive Pulmonary Disease (COPD) in the Canadian Urban Population: Results from the Canadian Obstructive Lung Disease (COLD) Study (2020) (0)
The efficiency of oxygen delivery through the lung airspaces to the blood vessel network (2009) (0)
The Lung Tissue Microbiome In COPD (2012) (0)
Quantitative computed tomography and visual emphysema scores: association with lung function decline (2023) (0)
1. PHYSIOLOGICAL ASPECTS OF BRONCHIAL HYPERRESPONSIVENESS (1992) (0)
Boxplots of gene expression levels in the lung for EGLN2 according to genotype groups for SNP rs4803369. (2013) (0)
Airways dimensions; changes in disease. (1981) (0)
Latent Viral Infections (2009) (0)
cT-Definable s ubtypes of chronic Obstructive Pulmonary Disease: A Statement of the (2015) (0)
Subclinical coronary artery disease at RCAF Greenwood. (1966) (0)
Fractal Dimensions of Airway Surfaces from Computed Tomography in Chronic Obstructive Pulmonary Disease (2022) (0)
A Comparison of Normal Lung Anatomy to Minimal to Established Fibrosis in Idiopathic Pulmonary Fibrosis (2019) (0)
Hypoxia Genes Associated with Different Infiltrating Immune Cells in Chronic Obstructive Plumonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF) (2022) (0)
microRNA profiling in pulmonary fibroblasts in COPD (2011) (0)
Pulmonary Circulation in Health and Disease, G. Cumming, G. Bonsignore (Eds.). Plenum Press, New York (1980), 405 (1982) (0)
obstructive pulmonary disease . and function in chronic Pulmonary vascular structure (2004) (0)
Histological Assessment of Remaining Terminal Bronchioles in PRMfSAD-Dominant Regions (2020) (0)
Measurements of small airways in emphysema (1971) (0)
Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma (2022) (0)
The relation of cigarette smoking to increased extracellular matrix in the layer of airway smooth muscle (2015) (0)
Normal Routine Spirometry Can Mask Clinical and Physiologic Detection of COPD and Emphysema in Symptomatic Smokers (2019) (0)
Glucocorticosteroids, inflammation and bronchial hyperreactivity : symposium at the 3rd Congress of the European Society of Pneumology, Basel, September 19, 1984 (1985) (0)
Small Airways Disease in Chronic Obstructive Pulmonary Disease: A 50 Years History (2017) (0)
Pulmonary structure: introduction. (1979) (0)
that demarginate during acute maximal exercise Expression of the cell adhesion molecules on leukocytes (2015) (0)
[The small airways in emphysema]. (1971) (0)
Correlation of Computed Tomographic Patterns with Morphological Tissue Changes in Idiopathic Pulmonary Fibrosis (2022) (0)
The inflammatory process in peripheral airways. (1985) (0)
Acute Hypersensitivity Pneumonitis in the Rabbit (2015) (0)
Structural changes in COPD (2011) (0)
Workshop on the Pulmonary Endothelial Cell (2015) (0)
Marijuana smoking: Health and socioeconomic impact in middle-aged and elderly adults (2016) (0)
Multiphoton microscopy based cryo-imaging of inflated frozen human lung sections at -60°C in healthy and COPD lungs (2013) (0)
Distribution of labelled mononuclear (MONO) and polymorphonuclear (PMN) leukocytes in the rabbit (1985) (0)
A comparison of paraseptal to centrilobular emphysema using computed and micro-computed tomography (2018) (0)
chord length to assess emphysema Commentaries on Viewpoint: Use of mean airspace (2015) (0)
Editorial: Pathophysiology of asthma. (1974) (0)
Fracture of the Thyroid Cartilage (1939) (0)
Lungstructure andfunction incigarette smokers (1994) (0)
neutrophils and shortens their transit in marrow Interleukin-6 induces demargination of intravascular (2016) (0)
Trauma, leukocytes and the lung (1986) (0)
Loss of small airways occurs in mild and moderate Chronic Obstructive Pulmonary Disease: a cross-sectional study (2018) (0)
Reply to: Broadening concepts of core pathobiology in various aspects of COPD development (2022) (0)
Differential Airway Involvement in Restrictive Phenotypes of Chronic Lung Allograft Dysfunction (2015) (0)
Prolapse of Both Ventricles of Morgagni (1938) (0)
methacholine by the application of RF energy in dogs Reduction in airway hyperresponsiveness to (2015) (0)
Stereological Assessment of Parenchyma and Small Airway Morphology Using Micro-Computed Tomography in Patients with Idiopathic Pulmonary Fibrosis (0)
Boeck's Sarcoidosis with Nasal Lesion (1946) (0)
Global Gene And MicroRNA Expression Profiling Identifies MicroRNA-Gene Regulatory Networks In The Lung Tissue Of Smokers With COPD (2012) (0)
Increased TLR3 Gene Expression In Epithelial Cells Of COPD Patients (2012) (0)
Factors Associated with Attrition in a Longitudinal Cohort of Older Adults in the Community. (2023) (0)
Blood counts , arterial blood gases , and blood pressure (2002) (0)
Protection against barbiturate anaesthesia death in rabbits. (1974) (0)
Canadian lung tissue biobank with associated clinical data supporting respiratory research for four decades (2021) (0)
Alteration In Decorin And Versican In The Lung Extra-Cellular Matrix In Centrilobular Emphysema (2012) (0)
Review: long term use of common medications for asthma reduces exacerbations in adults (2005) (0)
The Role Of Promoter Methylation In Regulating The Expression Of Genes Associated With COPD Progression (2010) (0)
Computed Tomography Total Vessel Count in Chronic Obstructive Pulmonary Disease: Association With Pulmonary Function (2023) (0)
Histological Estimation Of Airway Number In COPD (2011) (0)
The Increased Infiltration of Immune Cells in COPD Based on Quantitative Histology and CIBERSORT (2020) (0)
MiR-638 Regulates Gene Expression Changes In Human Lung Fibroblasts (2012) (0)
A New Method for Analyzing Gene Expression in Relation to the Progression of Both Small Airways Obstructive and Emphysematous Destructive Lesions in COPD. (2009) (0)
The cellular and molecular determinants of emphysematous destruction in COPD (2017) (0)
Investigating the Relationship Between Central Computer Tomography Airway Tree Features and Small Airways Disease in Chronic Obstructive Pulmonary Disease (0)
Pathobiology of Airway and Arterial Vascular Remodeling in Chronic Obstructive Pulmonary Disease (2023) (0)
Regional Variation Of Alveolar Number In Normal Human Lung (2010) (0)
Changes In Gene Expression With Progression Of Emphysematous Destruction In COPD (2010) (0)
Genetics of COPO (2004) (0)
AUTHORS' REPLY (1994) (0)

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