James Douglas Engel

James Douglas Engel's AcademicInfluence.com Rankings

James Douglas Engel

Computer Science

#6738

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#7102

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Machine Learning

#2286

World Rank

#2314

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Artificial Intelligence

#2559

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#2600

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Database

#3822

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#3977

Historical Rank

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Computer Science

James Douglas Engel's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley

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James Douglas Engel's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. (1999) (3144)
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation (2003) (793)
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis (1995) (661)
DNA-binding specificities of the GATA transcription factor family (1993) (627)
Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. (1990) (574)
MafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion (2005) (449)
Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. (2002) (439)
Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I (1980) (388)
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system (2000) (347)
A 200 base pair region at the 5′ end of the chicken adult β-globin gene is accessible to nuclease digestion (1981) (342)
Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer (1991) (318)
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. (2004) (300)
Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis (1993) (300)
The world according to Maf. (1997) (278)
Embryonic expression and cloning of the murine GATA-3 gene. (1994) (265)
Developmental regulation of β-globin gene switching (1988) (262)
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. (1994) (248)
Dynamics of GATA transcription factor expression during erythroid differentiation. (1993) (240)
Genetic Evidence that Small Maf Proteins Are Essential for the Activation of Antioxidant Response Element-Dependent Genes (2005) (238)
Expression of the transcription factor GATA‐3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus (1999) (235)
Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. (1993) (231)
Quantitation of RNA using the polymerase chain reaction. (1993) (222)
GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. (1997) (207)
MafB Is Essential for Renal Development and F4/80 Expression in Macrophages (2006) (191)
Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4. (1995) (190)
Effects of altered gene order or orientation of the locus control region on human β-globin gene expression in mice (1999) (183)
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. (1997) (175)
Looping, Linking, and Chromatin Activity New Insights into β-globin Locus Regulation (2000) (171)
A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. (2014) (170)
GATA-3 is required for early T lineage progenitor development (2009) (158)
Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA‐2 in urogenital development (1998) (157)
Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. (1995) (155)
Gata2 specifies serotonergic neurons downstream of sonic hedgehog (2004) (154)
Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction (2013) (154)
A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene (1986) (148)
In vivo requirements for GATA‐1 functional domains during primitive and definitive erythropoiesis (2001) (147)
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. (2012) (146)
Positive or Negative MARE-Dependent Transcriptional Regulation Is Determined by the Abundance of Small Maf Proteins (2000) (145)
Expression of delta-aminolevulinate synthase in avian cells: separate genes encode erythroid-specific and nonspecific isozymes. (1989) (144)
GATA2 is required for the generation of V2 interneurons. (2000) (142)
GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene. (1994) (139)
Hb switching in chickens (1980) (139)
The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. (1999) (132)
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies. (2000) (132)
Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors* (2002) (126)
v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (Band 3) gene (1988) (125)
The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. (1999) (119)
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche (2006) (111)
Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic β-Type Globin Promoters in Differentiated Adult Erythroid Cells (2011) (111)
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation (2007) (110)
An embryonic/fetal β‐type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer (2002) (110)
Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element* (2005) (106)
Developmental potential. (1992) (105)
Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation (2006) (105)
Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4 (2007) (104)
GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. (2012) (103)
Hypersensitive Site 2 Specifies a Unique Function within the Human β-Globin Locus Control Region To Stimulate Globin Gene Transcription (1999) (103)
GATA1-related leukaemias (2008) (102)
Hepatic Erythropoietin Gene Regulation by GATA-4* (2004) (102)
Replacement variant histone genes contain intervening sequences (1985) (100)
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. (1998) (100)
A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster. (1993) (99)
The beta-globin stage selector element factor is erythroid-specific promoter/enhancer binding protein NF-E4. (1989) (97)
Long range interaction of cis‐DNA elements mediated by architectural transcription factor Bach1 (1999) (96)
Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory Elements in the GATA-3 Locus (1999) (96)
Individual stage selector element mutations lead to reciprocal changes in beta- vs. epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching. (1992) (95)
Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice. (2000) (95)
Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver delta-aminolevulinate synthase. (1988) (95)
Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study (2017) (93)
Developmental regulation of human beta-globin gene transcription: a switch of loyalties? (1993) (93)
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation (2015) (88)
Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice (2000) (88)
Expression of the chicken GATA factor family during early erythroid development and differentiation. (1993) (83)
Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements (2006) (81)
GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (78)
Beta-globin YAC transgenes exhibit uniform expression levels but position effect variegation in mice. (2000) (78)
Recruitment of Transcription Complexes to the β-Globin Gene Locus in Vivo and in Vitro* (2004) (78)
The nucleotide sequence of the adult chicken alpha-globin genes. (1983) (77)
Genomic organization, DNA sequence, and expression of chicken embryonic histone genes. (1983) (74)
Induction of erythroid-specific gene expression in lymphoid cells. (1993) (74)
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice. (2015) (71)
A chicken histone H3 gene contains intervening sequences (1982) (71)
The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor*♦ (2010) (70)
Fetal Globin Gene Repressors as Drug Targets for Molecular Therapies To Treat the β-Globinopathies (2014) (67)
Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. (2016) (67)
Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3. (2011) (65)
Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences (1993) (62)
Structure and expression of the chicken ferritin H-subunit gene. (1987) (62)
Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique (2004) (62)
A minigene containing four discrete cis elements recapitulates GATA‐1 gene expression in vivo (2002) (61)
Reconstitution of Human β-Globin Locus Control Region Hypersensitive Sites in the Absence of Chromatin Assembly (2001) (61)
Developmental regulation of beta-globin gene switching. (1988) (61)
Graded Levels of GATA-1 Expression Modulate Survival, Proliferation, and Differentiation of Erythroid Progenitors* (2005) (60)
Analysis of the adult chicken beta-globin gene. Nucleotide sequence of the locus, microheterogeneity at the 5'-end of beta-globin mRNA, and aberrant nuclear RNA species. (1983) (60)
Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes. (1979) (59)
Multiple, Distant Gata2 Enhancers Specify Temporally and Tissue-Specific Patterning in the Developing Urogenital System (2004) (59)
Chromosomal arrangement of the chicken β-type globin genes (1981) (58)
Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development (2018) (57)
Subunit structure of chromatin is the same in plants and animals (1975) (57)
Characterization of the Murine mafF Gene* (1999) (55)
Embryonic Lethality and Fetal Liver Apoptosis in Mice Lacking All Three Small Maf Proteins (2011) (55)
Intergenic Transcription, Cell-Cycle and the Developmentally Regulated Epigenetic Profile of the Human Beta-Globin Locus (2007) (54)
Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements. (1997) (54)
Upstream and downstream of erythroid transcription factor GATA‐1 (1997) (54)
Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter. (1997) (54)
MafG Sumoylation Is Required for Active Transcriptional Repression (2006) (53)
Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation. (1994) (52)
Mutation of gene-proximal regulatory elements disrupts human ɛ-, γ-, and β-globin expression in yeast artificial chromosome transgenic mice (1997) (51)
Small Maf Compound Mutants Display Central Nervous System Neuronal Degeneration, Aberrant Transcription, and Bach Protein Mislocalization Coincident with Myoclonus and Abnormal Startle Response (2003) (51)
Human β-Globin Locus Control Region HS5Contains CTCF- and Developmental Stage-Dependent Enhancer-BlockingActivity in ErythroidCells (2003) (51)
The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. (2007) (51)
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia. (2004) (51)
Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. (1994) (50)
Fine Tuning of Globin Gene Expression by DNA Methylation (2006) (50)
GATA Transcription Factors (2002) (50)
Erythroid-specific transcription of the chicken histone H5 gene is directed by a 3′ enhancer (1987) (49)
Human T cell transcription factor GATA-3 stimulates HIV-1 expression. (1993) (49)
In situ mapping identifies distinct vascular niches for myelopoiesis (2021) (49)
Developmental transcriptome analysis of human erythropoiesis. (2014) (49)
An NK and T Cell Enhancer Lies 280 Kilobase Pairs 3′ to the Gata3 Structural Gene (2011) (47)
Transcription factor GATA‐3 is essential for lens development (2009) (46)
Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes (2011) (46)
Analysis of the closely linked adult chicken alpha-globin genes in recombinant DNAs. (1980) (46)
Regulation and function of transcription factor GATA-1 during red blood cell differentiation. (1996) (45)
Isolation of recombinant cDNAs encoding chicken erythroid delta-aminolevulinate synthase. (1985) (45)
Inferring Time-Varying Network Topologies from Gene Expression Data (2007) (43)
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis) (2016) (42)
Two different mRNAs are transcribed from a single genomic locus encoding the chicken erythrocyte anion transport proteins (band 3) (1988) (42)
Histone genes are clustered but not tandemly repeated in the chicken genome. (1981) (42)
Dosage-dependent rescue of definitive nephrogenesis by a distant Gata3 enhancer. (2007) (42)
Temperature-sensitive v-sea transformed erythroblasts: a model system to study gene expression during erythroid differentiation. (1988) (40)
Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model (2013) (40)
Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease. (2017) (39)
Analysis of the adult and embryonic chicken globin genes in chromosomal DNA. (1978) (38)
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background. (2003) (37)
Mesodermal‐ vs. neuronal‐specific expression of MafK is elicited by different promoters (1996) (37)
Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT (2008) (37)
Adult Stage γ-Globin Silencing Is Mediated by a Promoter Direct Repeat Element (2005) (37)
Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes (2010) (35)
GATA2 Regulates Body Water Homeostasis through Maintaining Aquaporin 2 Expression in Renal Collecting Ducts (2014) (35)
Inference of Biologically Relevant Gene Influence Networks Using the Directed Information Criterion (2006) (33)
Using directed information to build biologically relevant influence networks. (2007) (33)
Genomic imprinting recapitulated in the human β-globin locus (2005) (32)
Cloning and expression of chicken erythrocyte transglutaminase. (1992) (32)
Induction of hyperproliferative fetal megakaryopoiesis by an N‐terminally truncated GATA1 mutant (2009) (32)
Adult chicken alpha-globin genes alpha A and alpha D: no anemic shock alpha-globin exists in domestic chickens. (1981) (31)
A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells (1986) (31)
An unusual 5' splice sequence is efficiently utilized in vivo. (1984) (30)
Fetal Hemoglobin Induction by Epigenetic Drugs. (2018) (30)
Partial rescue of GATA-3 by yeast artificial chromosome transgenes. (1998) (30)
TRIM28 is essential for erythroblast differentiation in the mouse. (2013) (29)
Motif Discovery in Tissue-Specific Regulatory Sequences Using Directed Information (2007) (29)
GATA‐1 testis activation region is essential for Sertoli cell‐specific expression of GATA‐1 gene in transgenic mouse (2003) (29)
Neither MafA/L‐Maf nor MafB is essential for lens development in mice (2009) (28)
Transcriptional interference among the murine β-like globin genes (2007) (28)
The nucleotide sequence of the embryonic chicken beta-type globin genes. (1983) (27)
Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation (2016) (27)
Genomic imprinting recapitulated in the human beta-globin locus. (2005) (26)
PGC-1 Coactivator Activity Is Required for Murine Erythropoiesis (2014) (26)
GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. (2017) (26)
Complete nucleotide sequence of a chicken H2b histone gene. (1982) (25)
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression (2018) (25)
Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. (2019) (25)
Adult stage gamma-globin silencing is mediated by a promoter direct repeat element. (2005) (25)
[40] Cloning cDNA into λgt10 and λgt11 (1987) (25)
Two chicken erythrocyte band 3 mRNAs are generated by alternative transcriptional initiation and differential RNA splicing (1989) (25)
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126 (2019) (24)
Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes. (2015) (22)
The polyoma virus enhancer cannot substitute for DNase I core hypersensitive sites 2-4 in the human beta-globin LCR. (1999) (22)
Unusual structure of the chicken embryonic alpha-globin gene, pi'. (1983) (22)
Using Directed Information to Build Biologically Relevant Influence Networks (2007) (21)
The Aγ-globin 3′ element provides no unique function(s) for human β-globin locus gene regulation (1998) (20)
Transcription factor regulation of hematopoietic lineage cells. (1991) (20)
Looping, Linking, and Chromatin Minireview Activity: New Insights into b-globin Locus Regulation (2000) (19)
One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells (2000) (19)
Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs. (2016) (18)
Expression of cytoskeletal protein 4.1 during avian erythroid cellular maturation. (1987) (17)
UG4 Enhancer-Driven GATA-2 and Bone Morphogenetic Protein 4 Complementation Remedies the CAKUT Phenotype in Gata2 Hypomorphic Mutant Mice (2012) (17)
Defining the Functional Boundaries of the Gata2 Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene* (2008) (17)
cis and trans regulation of tissue-specific transcription (1992) (17)
Transcriptional interference among the murine beta-like globin genes. (2007) (16)
Reactivation of Fetal Hemoglobin for Treating β-Thalassemia and Sickle Cell Disease. (2017) (16)
Biochemical characterization of the developmental stage- and tissue-specific erythroid transcription factor, NF-E4. (1994) (15)
Structure and regulation of the chicken erythroid δ-aminolevulinate synthase gene (1994) (15)
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia. (2021) (15)
Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. (2014) (14)
Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons. (2017) (14)
The role of transcription factors in erythroid development. (1996) (14)
A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance (2015) (14)
GATA2‐dependent and region‐specific regulation of Gata2 transcription in the mouse midbrain (2009) (14)
Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice. (1997) (13)
Global dynamics of stage-specific transcription factor binding during thymocyte development (2018) (13)
Functional GATA-3 Binding Sites within Murine CD 8 c Upstream Regulatory Sequences (2003) (13)
Identification of cis-Regulatory Sequences in the Human Angiotensinogen Gene by Transgene Coplacement and Site-Specific Recombination (2005) (13)
Structure and regulation of the chicken GATA-3 gene. (1995) (13)
Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. (2018) (12)
Isolation of the chicken beta-globin gene and a linked embryonic beta-like globin gene from a chicken DNA recombinant library. (1979) (12)
Meticulous AP-1 factors (1994) (12)
Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons. (2018) (12)
Chicken histone H3.3B cDNA sequence confirms unusual 3' UTR structure. (1987) (11)
The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice. (1994) (11)
The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation. (2017) (11)
Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis (2017) (11)
Transcription of the chicken histone H5 gene is mediated by distinct tissue-specific elements within the promoter and the 3' enhancer (1989) (10)
Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect (2016) (10)
Modeling dynamic functional relationship networks and application to ex vivo human erythroid differentiation (2014) (10)
Small molecule therapeutics to treat the β-globinopathies. (2020) (10)
Transcription Factor Networks Specify Sympathetic and Adrenal Chromaffin Cell Differentiation (2007) (10)
EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis. (2020) (10)
The Nucleotide Sequence of the Adult Chicken a-Globin Genes * (2001) (10)
Chromosomal arrangement of the chicken beta-type globin genes. (1981) (10)
UNC0638 induces high levels of fetal hemoglobin expression in β-thalassemia/HbE erythroid progenitor cells (2020) (9)
Regulatory network inferred using expression data of small sample size: application and validation in erythroid system (2015) (9)
Unusual structure of the chicken embryonic a-globin gene, iT' (8)
A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression (2018) (8)
GATA1 and GATA2 Function in Hematopoietic Differentiation (2010) (8)
An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference. (2015) (8)
Biased, Non-equivalent Gene-Proximal and -Distal Binding Motifs of Orphan Nuclear Receptor TR4 in Primary Human Erythroid Cells (2014) (8)
Constricting restricted transcription: the (actively?) shrinking web. (2006) (7)
Cloning cDNA into lambda gt10 and lambda gt11. (1987) (7)
Spiral ganglion cell degeneration‐induced deafness as a consequence of reduced GATA factor activity (2019) (7)
Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis. (2019) (7)
Linear Distance from the Locus Control Region Determines ε-Globin Transcriptional Activity (2007) (7)
High‐level induction of fetal haemoglobin by pomalidomide in β‐thalassaemia/HbE erythroid progenitor cells (2020) (6)
Erratum: GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene (Molecular and Cellular Biology (2005) 25, 16 (7005-7020)) (2005) (6)
An erythroid to myeloid cell fate conversion is elicited by LSD1 inactivation. (2021) (6)
All of the human β‐type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice (2009) (5)
GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion (2017) (5)
Linear distance from the locus control region determines epsilon-globin transcriptional activity. (2007) (5)
Simple math for the β-globin locus control region (2001) (5)
High-Throughput Single-Cell Sequencing of both TCR-β Alleles (2018) (5)
Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq (2022) (4)
Structure and regulation of vertebrate δ‐aminolevulinate synthases (1994) (4)
In vivo Modulation of Human β-globin Gene Switching (2000) (4)
The A gamma-globin 3' element provides no unique function(s) for human beta-globin locus gene regulation. (1998) (4)
GATA3 is essential for separating patterning domains during facial morphogenesis. (2021) (4)
Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance (2021) (3)
SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II (2021) (3)
Identification of novel γ-globin inducers among all potential erythroid druggable targets (2022) (3)
LSD1 Inhibitors Induce Fetal Hemoglobin in Primary Human Erythroid Cells (2018) (3)
Using directed information for influence discovery in interconnected dynamical systems (2008) (3)
Gata3 hypomorphic mutant mice rescued with a YAC transgene suffer a glomerular mesangial cell defect (2016) (3)
Manifold embedding for understanding mechanisms of transcriptional regulation (2006) (2)
GATA2 functions in adrenal chromaffin cells (2020) (2)
Nuclear Receptors TR 2 and TR 4 Recruit Multiple Epigenetic Transcriptional Corepressors (2011) (2)
In vivo modulation of human beta-globin gene switching. (2000) (2)
Epigenetic activities in erythroid cell gene regulation. (2020) (2)
Analysis of the closely linked adult chicken a-globin genes in recombinant DNAs ( chromosomal linkage / intervening sequences / embryonic a-globin gene ) (2)
Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene. (1994) (2)
A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia (2021) (1)
The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision (2021) (1)
Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors (2019) (1)
THE ORGANIZATION OF CHICKEN GLOBIN GENES (1979) (1)
Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse (2019) (1)
Understanding Distal transcriptional Regulation from Sequence, Expression and interactome Perspectives (2010) (1)
GATA3 is essential for separating patterning domains during facial morphogenesis (2021) (1)
High throughput single cell sequencing of both T-cell-receptor-beta alleles (2018) (1)
mafB Deficient Mouse Results in Impaired Macrophage Differentiation. (2005) (1)
Three-dimensional mapping identifies distinct vascular niches for myelopoiesis (2020) (1)
Analysis of Fetal Hemoglobin Expression within Humanized Sickle Cell Disease Mice Overexpressing the TR2/4 Transgene. (2010) (1)
The chicken 3 / e-globin enhancer directs autonomously regulated , high-level expression of the chicken E-globin gene in transgenic mice ( evolution / hemoglobin switching / polymerase chain reaction / promoter competition / transcription ) (1)
Crystal Structure of the ligand binding domain of human testicular receptor 4 (2010) (0)
Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis (2019) (0)
3045 – MAPPING MYELOID DIFFERENTIATION IDENTIFIES A CSF1+ VASCULAR NICHE FOR MYELOPOIESIS (2020) (0)
GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (0)
Genetics and biochemistry of the embryonic to adult switch in the chicken epsilon- and beta-globin genes. (1989) (0)
Identification of Novel Regulators of Erythropoiesis Using Whole-Genome CRISPR-Cas9 Screening (2022) (0)
Gata3 hypomorphic mutant mice with YAC-transgenic partial rescue suffer glomerular mesangial cell defect (2016) (0)
Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Speciﬁcally with the Embryonic (cid:1) -Type Globin Promoters in Differentiated Adult Erythroid Cells (cid:1) (2011) (0)
3043 – A PIPELINE TO IMAGE HEMATOPOIETIC DIFFERENTIATION REVEALS THE ARCHITECTURE OF ERYTHROPOIESIS IN THE BONE MARROW (2020) (0)
Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development (2018) (0)
M1596 GATA3 and Nephrocan Are Expressed in Highly Restricted Patterns At the Developing Pylorus (2009) (0)
and Aorta-Gonads and Mesonephros Region The Mouse GATA-2 Gene is Expressed in the Para-Aortic Splanchnopleura (2013) (0)
APP-091 Caudal domain of urogenital mesenchymal GATA2 expression is essential for proper development of vesicoureteral junction(総会賞応募ポスター,第99回日本泌尿器科学会総会) (2011) (0)
Induction of Hyperproliferative Fetal Megakaryopoiesis by An N-Terminally Truncated GATA1 Mutant. (2008) (0)
RED CELLS , IRON , AND ERYTHROPOIESIS Compound loss of function of nuclear receptors Tr 2 and Tr 4 leads to induction of murine embryonic b-type globin genes (2015) (0)
Insights into the Future from Analysis of the Past Genetic Research and its Impact on the future of Personalized Medicine (2016) (0)
BAP1 deubiquitinase is a potent repressor of fetal hemoglobin biosynthesis (2018) (0)
Structure and expression of the chicken ferritin H-subunit gene (1987) (0)
Understanding Distal Transcriptional Regulation from Sequence Motif, Network Inference and Interactome Perspectives (2008) (0)
Zmiz 1-Notch 1 interaction in preT cells 1 Stage-specific roles for Zmiz 1 in Notch-dependent steps of early T-cell development (2018) (0)
An NK and T Cell Enhancer Lies 280 Kilobase Pairs 3 (cid:1) to the Gata3 Structural Gene (cid:1) (2011) (0)
Global dynamics of stage-specific transcription factor binding during thymocyte development (2018) (0)
Evaluation of interactions between DNA and transcription factors by surface plasmon resonance imaging technique (2006) (0)
Probabilistic data integration and visualization for understanding transcriptional regulation (2006) (0)
Combinatorial Effect of Pharmacological Inhibitors of Lsd-1 and DNMT on γ-Globin Synthesis in Cultured Baboon Bone Marrow Erythroid Progenitors (2012) (0)
Linear distance from the LCR determines the transciptional activity of ε-globin in human β-globin YAC transgenic mice (2007) (0)
A genetic test for transvection-like interchromosomal functional interaction at the mouse Rosa26 locus (2019) (0)
Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq (2022) (0)
GATA 2 haploinsufficiency accelerates EVI 1-driven leukemogenesis Running title : GATA 2 haploinsufficiency in 3 q AML (2017) (0)
Nucleic Acids Research (2010) (0)
GATA-3 participates in a mutually reinforcing transcriptional network in sympathoadrenal development (2006) (0)
Expression of 6-aminolevulinate synthase in avian cells: Separate genes encode erythroid-specific and nonspecific isozymes (erythrold-speciflc gene/heme biosynthesis) (2016) (0)
Epigenetic Activities in Erythroid Cell Gene Regulation Seminars in Hematology (2021) (0)
Isolation of recombinant cDNAs encoding chicken erythroid 6 aminolevulinate synthase ( antibody to 6-aminolevulinate synthase / red cell expression library ) (0)
No evidence for transvection in vivo by a superenhancer:promoter pair integrated into identical open chromatin at the Rosa26 locus (2018) (0)
Hozumi in a Mouse Model HemoglobinHereditary Persistence of Fetal Locus Causes Hbs 1 l-Myb Disruption of the (2013) (0)
Beta-globin gene regulation in chicken erythroleukemia cells. (1987) (0)
MafG-Null Mice Show Delayed Leukocyte Engraftment Following Whole Bone Marrow Transplant. (2006) (0)
The LSD1 Inhibitor RN-1 Increases γ-Globin Expression in Baboons By Targeting an Early Event Responsible for γ-Globin Repression (2018) (0)
867a GATA3 is Essential for Proper Morphogenesis of the Pylorus (2010) (0)
RED CELLS , IRON , AND ERYTHROPOIESIS The LSD 1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice (2015) (0)
In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis (2020) (0)
p53-Independent Pathways in Diamond Blackfan Anemia (2022) (0)
Directed-Information Based Feature-Selection for Tissue-Specific Sequences (2007) (0)
Murine embryos bearing an inactivating targeted deletion of gata 2 in the germline die (0)
Understanding Transcriptional Regulation Using De-novo Sequence Motif Discovery, Network Inference and Interactome Data (2007) (0)
thrombocytopenia FOG-1 association site phenocopies patients with X-linked deficient mice with GATA-1 lacking a - Transgenic rescue of GATA-1 (2013) (0)
Finding Sequence Features in Tissue-specific Sequences (2007) (0)
Summary Gata 2 specifies serotonergic neurons downstream of sonic hedgehog (2004) (0)

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