James Douglas Engel
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Computer Science
James Douglas Engel's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)James Douglas Engel's Published Works
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Published Works
- Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. (1999) (3144)
- Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation (2003) (793)
- Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis (1995) (661)
- DNA-binding specificities of the GATA transcription factor family (1993) (627)
- Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. (1990) (574)
- MafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion (2005) (449)
- Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. (2002) (439)
- Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I (1980) (388)
- Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system (2000) (347)
- A 200 base pair region at the 5′ end of the chicken adult β-globin gene is accessible to nuclease digestion (1981) (342)
- Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer (1991) (318)
- Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. (2004) (300)
- Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis (1993) (300)
- The world according to Maf. (1997) (278)
- Embryonic expression and cloning of the murine GATA-3 gene. (1994) (265)
- Developmental regulation of β-globin gene switching (1988) (262)
- Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. (1994) (248)
- Dynamics of GATA transcription factor expression during erythroid differentiation. (1993) (240)
- Genetic Evidence that Small Maf Proteins Are Essential for the Activation of Antioxidant Response Element-Dependent Genes (2005) (238)
- Expression of the transcription factor GATA‐3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus (1999) (235)
- Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. (1993) (231)
- Quantitation of RNA using the polymerase chain reaction. (1993) (222)
- GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. (1997) (207)
- MafB Is Essential for Renal Development and F4/80 Expression in Macrophages (2006) (191)
- Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4. (1995) (190)
- Effects of altered gene order or orientation of the locus control region on human β-globin gene expression in mice (1999) (183)
- GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. (1997) (175)
- Looping, Linking, and Chromatin Activity New Insights into β-globin Locus Regulation (2000) (171)
- A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. (2014) (170)
- GATA-3 is required for early T lineage progenitor development (2009) (158)
- Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA‐2 in urogenital development (1998) (157)
- Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. (1995) (155)
- Gata2 specifies serotonergic neurons downstream of sonic hedgehog (2004) (154)
- Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction (2013) (154)
- A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene (1986) (148)
- In vivo requirements for GATA‐1 functional domains during primitive and definitive erythropoiesis (2001) (147)
- Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. (2012) (146)
- Positive or Negative MARE-Dependent Transcriptional Regulation Is Determined by the Abundance of Small Maf Proteins (2000) (145)
- Expression of delta-aminolevulinate synthase in avian cells: separate genes encode erythroid-specific and nonspecific isozymes. (1989) (144)
- GATA2 is required for the generation of V2 interneurons. (2000) (142)
- GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene. (1994) (139)
- Hb switching in chickens (1980) (139)
- The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. (1999) (132)
- GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies. (2000) (132)
- Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors* (2002) (126)
- v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (Band 3) gene (1988) (125)
- The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. (1999) (119)
- Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche (2006) (111)
- Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic β-Type Globin Promoters in Differentiated Adult Erythroid Cells (2011) (111)
- A Gata2 intronic enhancer confers its pan-endothelia-specific regulation (2007) (110)
- An embryonic/fetal β‐type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer (2002) (110)
- Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element* (2005) (106)
- Developmental potential. (1992) (105)
- Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation (2006) (105)
- Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4 (2007) (104)
- GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. (2012) (103)
- Hypersensitive Site 2 Specifies a Unique Function within the Human β-Globin Locus Control Region To Stimulate Globin Gene Transcription (1999) (103)
- GATA1-related leukaemias (2008) (102)
- Hepatic Erythropoietin Gene Regulation by GATA-4* (2004) (102)
- Replacement variant histone genes contain intervening sequences (1985) (100)
- Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. (1998) (100)
- A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster. (1993) (99)
- The beta-globin stage selector element factor is erythroid-specific promoter/enhancer binding protein NF-E4. (1989) (97)
- Long range interaction of cis‐DNA elements mediated by architectural transcription factor Bach1 (1999) (96)
- Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory Elements in the GATA-3 Locus (1999) (96)
- Individual stage selector element mutations lead to reciprocal changes in beta- vs. epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching. (1992) (95)
- Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice. (2000) (95)
- Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver delta-aminolevulinate synthase. (1988) (95)
- Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study (2017) (93)
- Developmental regulation of human beta-globin gene transcription: a switch of loyalties? (1993) (93)
- Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation (2015) (88)
- Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice (2000) (88)
- Expression of the chicken GATA factor family during early erythroid development and differentiation. (1993) (83)
- Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements (2006) (81)
- GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (78)
- Beta-globin YAC transgenes exhibit uniform expression levels but position effect variegation in mice. (2000) (78)
- Recruitment of Transcription Complexes to the β-Globin Gene Locus in Vivo and in Vitro* (2004) (78)
- The nucleotide sequence of the adult chicken alpha-globin genes. (1983) (77)
- Genomic organization, DNA sequence, and expression of chicken embryonic histone genes. (1983) (74)
- Induction of erythroid-specific gene expression in lymphoid cells. (1993) (74)
- The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice. (2015) (71)
- A chicken histone H3 gene contains intervening sequences (1982) (71)
- The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor*♦ (2010) (70)
- Fetal Globin Gene Repressors as Drug Targets for Molecular Therapies To Treat the β-Globinopathies (2014) (67)
- Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. (2016) (67)
- Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3. (2011) (65)
- Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences (1993) (62)
- Structure and expression of the chicken ferritin H-subunit gene. (1987) (62)
- Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique (2004) (62)
- A minigene containing four discrete cis elements recapitulates GATA‐1 gene expression in vivo (2002) (61)
- Reconstitution of Human β-Globin Locus Control Region Hypersensitive Sites in the Absence of Chromatin Assembly (2001) (61)
- Developmental regulation of beta-globin gene switching. (1988) (61)
- Graded Levels of GATA-1 Expression Modulate Survival, Proliferation, and Differentiation of Erythroid Progenitors* (2005) (60)
- Analysis of the adult chicken beta-globin gene. Nucleotide sequence of the locus, microheterogeneity at the 5'-end of beta-globin mRNA, and aberrant nuclear RNA species. (1983) (60)
- Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes. (1979) (59)
- Multiple, Distant Gata2 Enhancers Specify Temporally and Tissue-Specific Patterning in the Developing Urogenital System (2004) (59)
- Chromosomal arrangement of the chicken β-type globin genes (1981) (58)
- Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development (2018) (57)
- Subunit structure of chromatin is the same in plants and animals (1975) (57)
- Characterization of the Murine mafF Gene* (1999) (55)
- Embryonic Lethality and Fetal Liver Apoptosis in Mice Lacking All Three Small Maf Proteins (2011) (55)
- Intergenic Transcription, Cell-Cycle and the Developmentally Regulated Epigenetic Profile of the Human Beta-Globin Locus (2007) (54)
- Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements. (1997) (54)
- Upstream and downstream of erythroid transcription factor GATA‐1 (1997) (54)
- Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter. (1997) (54)
- MafG Sumoylation Is Required for Active Transcriptional Repression (2006) (53)
- Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation. (1994) (52)
- Mutation of gene-proximal regulatory elements disrupts human ɛ-, γ-, and β-globin expression in yeast artificial chromosome transgenic mice (1997) (51)
- Small Maf Compound Mutants Display Central Nervous System Neuronal Degeneration, Aberrant Transcription, and Bach Protein Mislocalization Coincident with Myoclonus and Abnormal Startle Response (2003) (51)
- Human β-Globin Locus Control Region HS5Contains CTCF- and Developmental Stage-Dependent Enhancer-BlockingActivity in ErythroidCells (2003) (51)
- The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. (2007) (51)
- Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia. (2004) (51)
- Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. (1994) (50)
- Fine Tuning of Globin Gene Expression by DNA Methylation (2006) (50)
- GATA Transcription Factors (2002) (50)
- Erythroid-specific transcription of the chicken histone H5 gene is directed by a 3′ enhancer (1987) (49)
- Human T cell transcription factor GATA-3 stimulates HIV-1 expression. (1993) (49)
- In situ mapping identifies distinct vascular niches for myelopoiesis (2021) (49)
- Developmental transcriptome analysis of human erythropoiesis. (2014) (49)
- An NK and T Cell Enhancer Lies 280 Kilobase Pairs 3′ to the Gata3 Structural Gene (2011) (47)
- Transcription factor GATA‐3 is essential for lens development (2009) (46)
- Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes (2011) (46)
- Analysis of the closely linked adult chicken alpha-globin genes in recombinant DNAs. (1980) (46)
- Regulation and function of transcription factor GATA-1 during red blood cell differentiation. (1996) (45)
- Isolation of recombinant cDNAs encoding chicken erythroid delta-aminolevulinate synthase. (1985) (45)
- Inferring Time-Varying Network Topologies from Gene Expression Data (2007) (43)
- The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis) (2016) (42)
- Two different mRNAs are transcribed from a single genomic locus encoding the chicken erythrocyte anion transport proteins (band 3) (1988) (42)
- Histone genes are clustered but not tandemly repeated in the chicken genome. (1981) (42)
- Dosage-dependent rescue of definitive nephrogenesis by a distant Gata3 enhancer. (2007) (42)
- Temperature-sensitive v-sea transformed erythroblasts: a model system to study gene expression during erythroid differentiation. (1988) (40)
- Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model (2013) (40)
- Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease. (2017) (39)
- Analysis of the adult and embryonic chicken globin genes in chromosomal DNA. (1978) (38)
- Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background. (2003) (37)
- Mesodermal‐ vs. neuronal‐specific expression of MafK is elicited by different promoters (1996) (37)
- Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT (2008) (37)
- Adult Stage γ-Globin Silencing Is Mediated by a Promoter Direct Repeat Element (2005) (37)
- Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes (2010) (35)
- GATA2 Regulates Body Water Homeostasis through Maintaining Aquaporin 2 Expression in Renal Collecting Ducts (2014) (35)
- Inference of Biologically Relevant Gene Influence Networks Using the Directed Information Criterion (2006) (33)
- Using directed information to build biologically relevant influence networks. (2007) (33)
- Genomic imprinting recapitulated in the human β-globin locus (2005) (32)
- Cloning and expression of chicken erythrocyte transglutaminase. (1992) (32)
- Induction of hyperproliferative fetal megakaryopoiesis by an N‐terminally truncated GATA1 mutant (2009) (32)
- Adult chicken alpha-globin genes alpha A and alpha D: no anemic shock alpha-globin exists in domestic chickens. (1981) (31)
- A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells (1986) (31)
- An unusual 5' splice sequence is efficiently utilized in vivo. (1984) (30)
- Fetal Hemoglobin Induction by Epigenetic Drugs. (2018) (30)
- Partial rescue of GATA-3 by yeast artificial chromosome transgenes. (1998) (30)
- TRIM28 is essential for erythroblast differentiation in the mouse. (2013) (29)
- Motif Discovery in Tissue-Specific Regulatory Sequences Using Directed Information (2007) (29)
- GATA‐1 testis activation region is essential for Sertoli cell‐specific expression of GATA‐1 gene in transgenic mouse (2003) (29)
- Neither MafA/L‐Maf nor MafB is essential for lens development in mice (2009) (28)
- Transcriptional interference among the murine β-like globin genes (2007) (28)
- The nucleotide sequence of the embryonic chicken beta-type globin genes. (1983) (27)
- Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation (2016) (27)
- Genomic imprinting recapitulated in the human beta-globin locus. (2005) (26)
- PGC-1 Coactivator Activity Is Required for Murine Erythropoiesis (2014) (26)
- GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. (2017) (26)
- Complete nucleotide sequence of a chicken H2b histone gene. (1982) (25)
- BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression (2018) (25)
- Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. (2019) (25)
- Adult stage gamma-globin silencing is mediated by a promoter direct repeat element. (2005) (25)
- [40] Cloning cDNA into λgt10 and λgt11 (1987) (25)
- Two chicken erythrocyte band 3 mRNAs are generated by alternative transcriptional initiation and differential RNA splicing (1989) (25)
- GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126 (2019) (24)
- Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes. (2015) (22)
- The polyoma virus enhancer cannot substitute for DNase I core hypersensitive sites 2-4 in the human beta-globin LCR. (1999) (22)
- Unusual structure of the chicken embryonic alpha-globin gene, pi'. (1983) (22)
- Using Directed Information to Build Biologically Relevant Influence Networks (2007) (21)
- The Aγ-globin 3′ element provides no unique function(s) for human β-globin locus gene regulation (1998) (20)
- Transcription factor regulation of hematopoietic lineage cells. (1991) (20)
- Looping, Linking, and Chromatin Minireview Activity: New Insights into b-globin Locus Regulation (2000) (19)
- One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells (2000) (19)
- Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs. (2016) (18)
- Expression of cytoskeletal protein 4.1 during avian erythroid cellular maturation. (1987) (17)
- UG4 Enhancer-Driven GATA-2 and Bone Morphogenetic Protein 4 Complementation Remedies the CAKUT Phenotype in Gata2 Hypomorphic Mutant Mice (2012) (17)
- Defining the Functional Boundaries of the Gata2 Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene* (2008) (17)
- cis and trans regulation of tissue-specific transcription (1992) (17)
- Transcriptional interference among the murine beta-like globin genes. (2007) (16)
- Reactivation of Fetal Hemoglobin for Treating β-Thalassemia and Sickle Cell Disease. (2017) (16)
- Biochemical characterization of the developmental stage- and tissue-specific erythroid transcription factor, NF-E4. (1994) (15)
- Structure and regulation of the chicken erythroid δ-aminolevulinate synthase gene (1994) (15)
- Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia. (2021) (15)
- Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. (2014) (14)
- Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons. (2017) (14)
- The role of transcription factors in erythroid development. (1996) (14)
- A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance (2015) (14)
- GATA2‐dependent and region‐specific regulation of Gata2 transcription in the mouse midbrain (2009) (14)
- Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice. (1997) (13)
- Global dynamics of stage-specific transcription factor binding during thymocyte development (2018) (13)
- Functional GATA-3 Binding Sites within Murine CD 8 c Upstream Regulatory Sequences (2003) (13)
- Identification of cis-Regulatory Sequences in the Human Angiotensinogen Gene by Transgene Coplacement and Site-Specific Recombination (2005) (13)
- Structure and regulation of the chicken GATA-3 gene. (1995) (13)
- Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. (2018) (12)
- Isolation of the chicken beta-globin gene and a linked embryonic beta-like globin gene from a chicken DNA recombinant library. (1979) (12)
- Meticulous AP-1 factors (1994) (12)
- Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons. (2018) (12)
- Chicken histone H3.3B cDNA sequence confirms unusual 3' UTR structure. (1987) (11)
- The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice. (1994) (11)
- The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation. (2017) (11)
- Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis (2017) (11)
- Transcription of the chicken histone H5 gene is mediated by distinct tissue-specific elements within the promoter and the 3' enhancer (1989) (10)
- Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect (2016) (10)
- Modeling dynamic functional relationship networks and application to ex vivo human erythroid differentiation (2014) (10)
- Small molecule therapeutics to treat the β-globinopathies. (2020) (10)
- Transcription Factor Networks Specify Sympathetic and Adrenal Chromaffin Cell Differentiation (2007) (10)
- EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis. (2020) (10)
- The Nucleotide Sequence of the Adult Chicken a-Globin Genes * (2001) (10)
- Chromosomal arrangement of the chicken beta-type globin genes. (1981) (10)
- UNC0638 induces high levels of fetal hemoglobin expression in β-thalassemia/HbE erythroid progenitor cells (2020) (9)
- Regulatory network inferred using expression data of small sample size: application and validation in erythroid system (2015) (9)
- Unusual structure of the chicken embryonic a-globin gene, iT' (8)
- A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression (2018) (8)
- GATA1 and GATA2 Function in Hematopoietic Differentiation (2010) (8)
- An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference. (2015) (8)
- Biased, Non-equivalent Gene-Proximal and -Distal Binding Motifs of Orphan Nuclear Receptor TR4 in Primary Human Erythroid Cells (2014) (8)
- Constricting restricted transcription: the (actively?) shrinking web. (2006) (7)
- Cloning cDNA into lambda gt10 and lambda gt11. (1987) (7)
- Spiral ganglion cell degeneration‐induced deafness as a consequence of reduced GATA factor activity (2019) (7)
- Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis. (2019) (7)
- Linear Distance from the Locus Control Region Determines ε-Globin Transcriptional Activity (2007) (7)
- High‐level induction of fetal haemoglobin by pomalidomide in β‐thalassaemia/HbE erythroid progenitor cells (2020) (6)
- Erratum: GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene (Molecular and Cellular Biology (2005) 25, 16 (7005-7020)) (2005) (6)
- An erythroid to myeloid cell fate conversion is elicited by LSD1 inactivation. (2021) (6)
- All of the human β‐type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice (2009) (5)
- GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion (2017) (5)
- Linear distance from the locus control region determines epsilon-globin transcriptional activity. (2007) (5)
- Simple math for the β-globin locus control region (2001) (5)
- High-Throughput Single-Cell Sequencing of both TCR-β Alleles (2018) (5)
- Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq (2022) (4)
- Structure and regulation of vertebrate δ‐aminolevulinate synthases (1994) (4)
- In vivo Modulation of Human β-globin Gene Switching (2000) (4)
- The A gamma-globin 3' element provides no unique function(s) for human beta-globin locus gene regulation. (1998) (4)
- GATA3 is essential for separating patterning domains during facial morphogenesis. (2021) (4)
- Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance (2021) (3)
- SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II (2021) (3)
- Identification of novel γ-globin inducers among all potential erythroid druggable targets (2022) (3)
- LSD1 Inhibitors Induce Fetal Hemoglobin in Primary Human Erythroid Cells (2018) (3)
- Using directed information for influence discovery in interconnected dynamical systems (2008) (3)
- Gata3 hypomorphic mutant mice rescued with a YAC transgene suffer a glomerular mesangial cell defect (2016) (3)
- Manifold embedding for understanding mechanisms of transcriptional regulation (2006) (2)
- GATA2 functions in adrenal chromaffin cells (2020) (2)
- Nuclear Receptors TR 2 and TR 4 Recruit Multiple Epigenetic Transcriptional Corepressors (2011) (2)
- In vivo modulation of human beta-globin gene switching. (2000) (2)
- Epigenetic activities in erythroid cell gene regulation. (2020) (2)
- Analysis of the closely linked adult chicken a-globin genes in recombinant DNAs ( chromosomal linkage / intervening sequences / embryonic a-globin gene ) (2)
- Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene. (1994) (2)
- A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia (2021) (1)
- The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision (2021) (1)
- Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors (2019) (1)
- THE ORGANIZATION OF CHICKEN GLOBIN GENES (1979) (1)
- Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse (2019) (1)
- Understanding Distal transcriptional Regulation from Sequence, Expression and interactome Perspectives (2010) (1)
- GATA3 is essential for separating patterning domains during facial morphogenesis (2021) (1)
- High throughput single cell sequencing of both T-cell-receptor-beta alleles (2018) (1)
- mafB Deficient Mouse Results in Impaired Macrophage Differentiation. (2005) (1)
- Three-dimensional mapping identifies distinct vascular niches for myelopoiesis (2020) (1)
- Analysis of Fetal Hemoglobin Expression within Humanized Sickle Cell Disease Mice Overexpressing the TR2/4 Transgene. (2010) (1)
- The chicken 3 / e-globin enhancer directs autonomously regulated , high-level expression of the chicken E-globin gene in transgenic mice ( evolution / hemoglobin switching / polymerase chain reaction / promoter competition / transcription ) (1)
- Crystal Structure of the ligand binding domain of human testicular receptor 4 (2010) (0)
- Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis (2019) (0)
- 3045 – MAPPING MYELOID DIFFERENTIATION IDENTIFIES A CSF1+ VASCULAR NICHE FOR MYELOPOIESIS (2020) (0)
- GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (0)
- Genetics and biochemistry of the embryonic to adult switch in the chicken epsilon- and beta-globin genes. (1989) (0)
- Identification of Novel Regulators of Erythropoiesis Using Whole-Genome CRISPR-Cas9 Screening (2022) (0)
- Gata3 hypomorphic mutant mice with YAC-transgenic partial rescue suffer glomerular mesangial cell defect (2016) (0)
- Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic (cid:1) -Type Globin Promoters in Differentiated Adult Erythroid Cells (cid:1) (2011) (0)
- 3043 – A PIPELINE TO IMAGE HEMATOPOIETIC DIFFERENTIATION REVEALS THE ARCHITECTURE OF ERYTHROPOIESIS IN THE BONE MARROW (2020) (0)
- Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development (2018) (0)
- M1596 GATA3 and Nephrocan Are Expressed in Highly Restricted Patterns At the Developing Pylorus (2009) (0)
- and Aorta-Gonads and Mesonephros Region The Mouse GATA-2 Gene is Expressed in the Para-Aortic Splanchnopleura (2013) (0)
- APP-091 Caudal domain of urogenital mesenchymal GATA2 expression is essential for proper development of vesicoureteral junction(総会賞応募ポスター,第99回日本泌尿器科学会総会) (2011) (0)
- Induction of Hyperproliferative Fetal Megakaryopoiesis by An N-Terminally Truncated GATA1 Mutant. (2008) (0)
- RED CELLS , IRON , AND ERYTHROPOIESIS Compound loss of function of nuclear receptors Tr 2 and Tr 4 leads to induction of murine embryonic b-type globin genes (2015) (0)
- Insights into the Future from Analysis of the Past Genetic Research and its Impact on the future of Personalized Medicine (2016) (0)
- BAP1 deubiquitinase is a potent repressor of fetal hemoglobin biosynthesis (2018) (0)
- Structure and expression of the chicken ferritin H-subunit gene (1987) (0)
- Understanding Distal Transcriptional Regulation from Sequence Motif, Network Inference and Interactome Perspectives (2008) (0)
- Zmiz 1-Notch 1 interaction in preT cells 1 Stage-specific roles for Zmiz 1 in Notch-dependent steps of early T-cell development (2018) (0)
- An NK and T Cell Enhancer Lies 280 Kilobase Pairs 3 (cid:1) to the Gata3 Structural Gene (cid:1) (2011) (0)
- Global dynamics of stage-specific transcription factor binding during thymocyte development (2018) (0)
- Evaluation of interactions between DNA and transcription factors by surface plasmon resonance imaging technique (2006) (0)
- Probabilistic data integration and visualization for understanding transcriptional regulation (2006) (0)
- Combinatorial Effect of Pharmacological Inhibitors of Lsd-1 and DNMT on γ-Globin Synthesis in Cultured Baboon Bone Marrow Erythroid Progenitors (2012) (0)
- Linear distance from the LCR determines the transciptional activity of ε-globin in human β-globin YAC transgenic mice (2007) (0)
- A genetic test for transvection-like interchromosomal functional interaction at the mouse Rosa26 locus (2019) (0)
- Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq (2022) (0)
- GATA 2 haploinsufficiency accelerates EVI 1-driven leukemogenesis Running title : GATA 2 haploinsufficiency in 3 q AML (2017) (0)
- Nucleic Acids Research (2010) (0)
- GATA-3 participates in a mutually reinforcing transcriptional network in sympathoadrenal development (2006) (0)
- Expression of 6-aminolevulinate synthase in avian cells: Separate genes encode erythroid-specific and nonspecific isozymes (erythrold-speciflc gene/heme biosynthesis) (2016) (0)
- Epigenetic Activities in Erythroid Cell Gene Regulation Seminars in Hematology (2021) (0)
- Isolation of recombinant cDNAs encoding chicken erythroid 6 aminolevulinate synthase ( antibody to 6-aminolevulinate synthase / red cell expression library ) (0)
- No evidence for transvection in vivo by a superenhancer:promoter pair integrated into identical open chromatin at the Rosa26 locus (2018) (0)
- Hozumi in a Mouse Model HemoglobinHereditary Persistence of Fetal Locus Causes Hbs 1 l-Myb Disruption of the (2013) (0)
- Beta-globin gene regulation in chicken erythroleukemia cells. (1987) (0)
- MafG-Null Mice Show Delayed Leukocyte Engraftment Following Whole Bone Marrow Transplant. (2006) (0)
- The LSD1 Inhibitor RN-1 Increases γ-Globin Expression in Baboons By Targeting an Early Event Responsible for γ-Globin Repression (2018) (0)
- 867a GATA3 is Essential for Proper Morphogenesis of the Pylorus (2010) (0)
- RED CELLS , IRON , AND ERYTHROPOIESIS The LSD 1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice (2015) (0)
- In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis (2020) (0)
- p53-Independent Pathways in Diamond Blackfan Anemia (2022) (0)
- Directed-Information Based Feature-Selection for Tissue-Specific Sequences (2007) (0)
- Murine embryos bearing an inactivating targeted deletion of gata 2 in the germline die (0)
- Understanding Transcriptional Regulation Using De-novo Sequence Motif Discovery, Network Inference and Interactome Data (2007) (0)
- thrombocytopenia FOG-1 association site phenocopies patients with X-linked deficient mice with GATA-1 lacking a - Transgenic rescue of GATA-1 (2013) (0)
- Finding Sequence Features in Tissue-specific Sequences (2007) (0)
- Summary Gata 2 specifies serotonergic neurons downstream of sonic hedgehog (2004) (0)
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What Schools Are Affiliated With James Douglas Engel?
James Douglas Engel is affiliated with the following schools: