James Eberwine | Academic Influence

James Eberwine's AcademicInfluence.com Rankings

James Eberwine

Biology

#7848

World Rank

#10830

Historical Rank

Molecular Biology

#2319

World Rank

#2354

Historical Rank

Neuroscience

#2417

World Rank

#2482

Historical Rank

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Biology

James Eberwine's Degrees

PhD Pharmacology University of Pennsylvania
Bachelors Biology University of California, San Diego

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Why Is James Eberwine Influential?

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According to Wikipedia, James H. Eberwine is an American molecular neurobiologist. He is the Elmer Holmes Bobst Professor of Pharmacology at the University of Pennsylvania. Early life and education Eberwine was born to parents Mary Jo and Paul Eberwine. He graduated from Yale University with a Bachelor of Science degree in biochemistry and earned his graduate degrees in the same subject at Columbia University. Following graduation, Eberwine married Joan-Marie Kienlen, an administrative assistant at the University of Pennsylvania, in 1993.

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James Eberwine's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Amplified RNA synthesized from limited quantities of heterogeneous cDNA. (1990) (1312)
The Human Cell Atlas (2017) (1285)
Analysis of gene expression in single live neurons. (1992) (933)
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. (1997) (656)
Mammalian cell transfection: the present and the future (2010) (560)
RNA Cargoes Associating with FMRP Reveal Deficits in Cellular Functioning in Fmr1 Null Mice (2003) (517)
Dopamine receptor subtypes colocalize in rat striatonigral neurons. (1992) (419)
Expression profile of transcripts in Alzheimer's disease tangle‐bearing CA1 neurons (2000) (328)
Molecular Characterization of the Dendritic Growth Cone: Regulated mRNA Transport and Local Protein Synthesis (1996) (272)
On the nature and differential distribution of mRNAs in hippocampal neurites: implications for neuronal functioning. (1994) (272)
The promise of single-cell sequencing (2013) (253)
Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. (2002) (232)
Localization and translation of mRNA in dentrites and axons (2001) (220)
Immunoprecipitation of mRNA-protein complexes (2006) (213)
Glucocorticoid regulation of pro-opiomelanocortin gene transcription in the rat pituitary. (1984) (194)
Cellular and molecular characterization of Ca2+ currents in acutely isolated, adult rat neostriatal neurons (1994) (194)
Identification of a Circadian Output Circuit for Rest:Activity Rhythms in Drosophila (2014) (188)
Embryonic neuronal markers in tuberous sclerosis: single-cell molecular pathology. (1996) (182)
Preparation of cDNA from single cells and subcellular regions. (1999) (165)
Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal CA1 neurons (1992) (164)
Local translation of classes of mRNAs that are targeted to neuronal dendrites (2001) (160)
Transcriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue (2014) (157)
Presence and phosphorylation of transcription factors in developing dendrites. (1998) (149)
Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques (1997) (144)
DJ‐1 colocalizes with tau inclusions: A link between parkinsonism and dementia (2004) (144)
Cytoplasmic Intron Sequence-Retaining Transcripts Can Be Dendritically Targeted via ID Element Retrotransposons (2011) (140)
Amplification of mRNA populations using aRNA generated from immobilized oligo(dT)-T7 primed cDNA. (1996) (136)
Identification of sites for exponential translation in living dendrites (2001) (136)
Stimulation of glutamate receptor protein synthesis and membrane insertion within isolated neuronal dendrites. (2000) (132)
Analysis of Subcellularly Localized mRNAs Using in Situ Hybridization, mRNA Amplification, and Expression Profiling (2002) (127)
Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques (1999) (126)
Corticosteroid Regulation of Ion Channel Conductances and mRNA Levels in Individual Hippocampal CA1 Neurons (1998) (123)
Region-directed phototransfection reveals the functional significance of a dendritically synthesized transcription factor (2006) (117)
In situ transcription: specific synthesis of complementary DNA in fixed tissue sections. (1988) (114)
RNA splicing capability of live neuronal dendrites. (2005) (114)
Complex transcriptional regulation by glucocorticoids and corticotropin-releasing hormone of proopiomelanocortin gene expression in rat pituitary cultures. (1987) (110)
In situ hybridization : applications to neurobiology (1987) (105)
Melanocyte‐like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers (2009) (95)
Single-Cell Gene Expression Analysis: Implications for Neurodegenerative and Neuropsychiatric Disorders (2004) (91)
Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization (2000) (91)
Expression of mRNAs Encoding for Two Different Olfactory Receptors in a Subset of Olfactory Receptor Neurons (2000) (90)
Internexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturity (1997) (85)
Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation (2015) (83)
Protein quantification from complex protein mixtures using a proteomics methodology with single-cell resolution (2001) (82)
Transcriptome Analysis of Single Cells (2011) (82)
Transcriptome transfer produces a predictable cellular phenotype (2009) (81)
Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy. (2011) (79)
Insulin Causes Hyperthermia by Direct Inhibition of Warm-Sensitive Neurons (2009) (79)
Traumatic Brain Injury Alters the Molecular Fingerprint of TUNEL-Positive Cortical Neurons In Vivo: A Single-Cell Analysis (2000) (75)
Multiplicity of glutamate receptor subunits in single striatal neurons: an RNA amplification study. (1996) (75)
In vivo identification of ribonucleoprotein-RNA interactions (2006) (72)
Single-cell molecular biology (2001) (68)
What Is Your Conceptual Definition of "Cell Type" in the Context of a Mature Organism? (2017) (66)
Cytoplasmic BKCa channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons (2008) (65)
Diversity of glutamate receptor subunit mRNA expression within live hippocampal CA1 neurons. (1993) (65)
Intron retention facilitates splice variant diversity in calcium-activated big potassium channel populations (2010) (64)
Variation is function: Are single cell differences functionally important? (2015) (63)
Elk-1 associates with the mitochondrial permeability transition pore complex in neurons. (2006) (59)
Genetic Basis of Susceptibility to Environmentally Induced Neural Tube Defects (2000) (59)
Cytoplasmic intron retention, function, splicing, and the sentinel RNA hypothesis (2014) (58)
Complementary DNA synthesis in situ: methods and applications. (1992) (58)
Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics. (2017) (58)
Presence of mRNA for glutamic acid decarboxylase in both excitatory and inhibitory neurons. (1996) (56)
Serotonergic neuron regulation informed by in vivo single‐cell transcriptomics (2014) (54)
Expression Profiling Following Traumatic Brain Injury: A Review (2002) (53)
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment (2019) (52)
Hormonal Regulation of POMC Gene Expression in Pituitary (1987) (47)
CAG trinucleotide RNA repeats interact with RNA-binding proteins. (1996) (46)
Neuron-Specific mRNA Complexity Responses during Hippocampal Apoptosis after Traumatic Brain Injury (2004) (45)
Acromegaly and pheochromocytoma: a multiple endocrine syndrome caused by a plurihormonal adrenal medullary tumor. (1986) (44)
Glucocorticoid regulation of proopiomelanocortin gene expression in rodent pituitary. (1982) (43)
RNA: state memory and mediator of cellular phenotype. (2010) (42)
Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons (2018) (42)
Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. (2020) (41)
Ruthenium-caged antisense morpholinos for regulating gene expression in zebrafish embryos (2015) (40)
Cellular adaptation to opiates alters ion-channel mRNA levels. (1994) (39)
Molecular Pathology of Alzheimer’s Disease and Related Disorders (1999) (38)
Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing. (2017) (38)
Single‐cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis (2016) (37)
Expression profiling of small cellular samples in cancer: less is more (2004) (37)
Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors* (2011) (36)
Subcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-Sequence Retaining Transcripts in Mouse and Rat Neurons (2013) (36)
A protocol for PAIR: PNA-assisted identification of RNA binding proteins in living cells (2006) (35)
Assessing characteristics of RNA amplification methods for single cell RNA sequencing (2016) (35)
Transcriptome transfer provides a model for understanding the phenotype of cardiomyocytes (2011) (33)
Developmental expression of proenkephalin mRNA and peptides in rat striatum. (1989) (33)
A Neurotoxic Phosphoform of Elk-1 Associates with Inclusions from Multiple Neurodegenerative Diseases (2010) (29)
Drug targets: single-cell transcriptomics hastens unbiased discovery. (2012) (29)
Expression Profile Analysis of Neurodegenerative Disease: Advances in Specificity and Resolution (2004) (28)
mRNA for the EAAC1 subtype of glutamate transporter is present in neuronal dendrites in vitro and dramatically increases in vivo after a seizure (2011) (27)
Mechanisms of translational control in dendrites (2003) (27)
Subcellular neuropharmacology: the importance of intracellular targeting. (2009) (24)
Gene expression profiling in the amygdala: An approach to examine the molecular substrates of mammalian behavior (2001) (23)
Patch-Clamp Techniques for Studying Potassium Currents in Mammalian Brain Neurons (1994) (23)
Analysis of mRNA Populations from Single Live and Fixed Cells of the Central Nervous System (1997) (23)
In situ hybridization in neurobiology : advances in methodology (1994) (22)
Single-cell antisense RNA amplification and microarray analysis as a tool for studying neurological degeneration and restoration. (2002) (21)
Single neurons as experimental systems in molecular biology (2004) (21)
Regulation of both preproenkephalin mRNA and its derived opioids by haloperidol--a method for measurement of peptides and mRNA in the same tissue extract. (1990) (21)
Analysis of pro-opiomelancortin gene structure and function. (1983) (20)
Cellular Deconstruction: Finding Meaning in Individual Cell Variation. (2015) (20)
Quantitative biology of single neurons (2012) (20)
Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. (1997) (19)
Single-neuron isolation for RNA analysis using pipette capture and laser capture microdissection. (2015) (19)
Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma. (2013) (19)
Methodological Considerations Regarding Single-Cell Gene Expression Profiling for Brain Injury (2004) (18)
Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution (2014) (18)
Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects. (1993) (18)
mRNA transport to and translation in neuronal dendrites (2006) (18)
Efficient Synthesis of Light‐Triggered Circular Antisense Oligonucleotides Targeting Cellular Protein Expression (2018) (17)
Fragile X syndrome: (What's) lost in translation? (2004) (17)
Review : Single-Cell mRNA Amplification: Implications for Basic and Clinical Neuroscience (1995) (17)
Avian Primordial Germ Cells Contribute to and Interact With the Extracellular Matrix During Early Migration (2019) (16)
Transcription factors in dendrites: dendritic imprinting of the cellular nucleus. (2001) (15)
Amplification of mRNAs from single, fixed, TUNEL-positive cells. (1998) (15)
Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model. (1994) (15)
The BRAIN Initiative and Neuroethics: Enabling and Enhancing Neuroscience Advances for Society (2020) (15)
Single-cell transcriptomics for drug target discovery. (2013) (14)
Cytoplasmic proteins interact with a translational control element in the protein-coding region of proopiomelanocortin mRNA. (1999) (13)
Dendritic glutamate receptor mRNAs show contingent local hotspot-dependent translational dynamics. (2013) (13)
Characterization and regulation of a cDNA clone for rat pancreastatin. (1990) (13)
Micro- and Nano-Devices for Studying Subcellular Biology. (2020) (12)
Mechanisms of neuronal plasticity as analyzed at the single cell level. (1995) (12)
Molecular Biology of Axons “A Turning Point…” (2001) (12)
Perspectives on cell reprogramming with RNA. (2012) (12)
Analysis of POMC gene expression by transcription assay and in situ hybridization histochemistry. (1983) (12)
Single-cell molecular biology: implications for the diagnosis and treatment of neurological disease. (1999) (10)
Single-cell molecular biology implications for diagnosis and treatment of neurologic disease (2003) (10)
Author response: The Human Cell Atlas (2017) (10)
Ultrasensitive Single Extracellular Vesicle Detection Using High Throughput Droplet Digital Enzyme-Linked Immunosorbent Assay. (2022) (10)
In Situ mRNA Hybridization: Standard Procedures and Novel Approaches (1989) (9)
Frequent lack of translation of antigen presentation–associated molecules MHC class I, CD1a and B2‐microglobulin in Reed‐Sternberg cells (2000) (9)
The assessment of genomic alterations using DNA arrays following traumatic brain injury: a review. (2001) (9)
mRNA structure, in situ, as assessed by microscopic techniques (1993) (9)
Toward a Fully Automated High-Throughput Phototransfection System (2010) (8)
PAIR technology: exon-specific RNA-binding protein isolation in live cells. (2011) (8)
Down the Rabbit Hole of Single-Cell Genome Analysis. (2017) (8)
The molecular biology of addictive drugs (2008) (7)
OLIGONUCLEOTIDE PROBE FOR TRANSCRIPTOME IN VIVO ANALYSIS (TIVA) OF SINGLE NEURONS WITH MINIMAL BACKGROUND. (2020) (7)
In situ hybridization (1987) (7)
The successes and future prospects of the linear antisense RNA amplification methodology (2018) (7)
Hunting in the calm before the storm (2000) (6)
mRNA methods used in dissecting gene expression of the brain (2005) (6)
Isolation of enzyme cDNA clones by enzyme immunodetection assay: isolation of a peptide acetyltransferase. (1987) (6)
Use of the teleost saccule to identify genes involved in inner ear function. (1995) (6)
[1] – Complementary DNA Synthesis in Situ: Methods and Applications (1995) (5)
Astrocytes promote ethanol-induced enhancement of intracellular Ca2+ signals through intercellular communication with neurons (2021) (5)
Antisense RNA amplification for target assessment of total mRNA from a single cell. (2014) (5)
Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Tissues and Cells. (2015) (5)
Aberrant production and regulation of proopiomelanocortin-derived peptides in ectopic Cushing's syndrome. (1988) (5)
Photoactivatable Circular Caged Oligonucleotides for Transcriptome In Vivo Analysis (TIVA). (2021) (4)
Cell Surface Protein mRNAs Show Differential Transcription in Pyramidal and Fast-Spiking Cells as Revealed by Single-Cell Sequencing. (2020) (4)
Live Cell Genomics: RNA Exon-Specific RNA-Binding Protein Isolation. (2015) (4)
Glucocorticoid and Mineralocorticoid Receptors as Transcription Factors (1999) (4)
RNA expression levels of membrane proteins involved in Ca influx are regulated by corticosteroid receptor stimulation: a single-cell study (1996) (3)
Dendritic Localization of mRNA and Local Protein Synthesis (1999) (3)
Transcription Factors in the Central Nervous System (2012) (2)
Identification of RNA cargoes by antibody-positioned RNA amplification. (2015) (2)
19 - Molecular Correlates of Corticosterone Action in Hippocampal Subregions (1994) (2)
Commentary: "Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and Its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing. (2021) (1)
Caspase-activated oligonucleotide probe. (2020) (1)
Nucleic Acid Introduction into Primary Neurons and Glia (2009) (1)
Assessing the measurement transfer function of single-cell RNA sequencing (2016) (1)
Commentary: "Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and Its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing. (2021) (1)
An approach to the molecular biology of opiate tolerance: identification of opiate-regulated transcripts. (1991) (1)
Regulation of Transcription by Transcription Factors (1999) (1)
Somatomedin Gene Expression (1987) (1)
Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Single Cells from Complex Tissues. (2021) (0)
Single cell transcriptomics and epigenomics methods provide high resolution genomics profiling of brain disorders (2021) (0)
Genomics Approaches to the Study of Neurodegeneration (2008) (0)
Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons (2019) (0)
Methods and compositions for the identification of RNA-binding proteins (2004) (0)
Identifying and quantifying rnas and dnas associated with rna and dna binding proteins (2001) (0)
Additional file 8: of Assessing characteristics of RNA amplification methods for single cell RNA sequencing (2016) (0)
192. Single cell microarray analysis of multigenic diseases (2000) (0)
Calcium Signals across a Large Active Zone (2004) (0)
The Transcriptional Process (1999) (0)
Single Cell Spatial Chromatin Analysis of Fixed Immunocytochemically Identified Neuronal Cells (2019) (0)
Single-Cell Transcriptomics in the Brain (2013) (0)
Single Cell Molecular Analysis Procedures (2009) (0)
Towards fully automated phototransfection (2009) (0)
Single-Cell Analysis of Long Noncoding RNAs (lncRNAs) in Mouse Brain Cells. (2020) (0)
Subcellular Genomics: Pervasive within-mitochondrion SNV heteroplasmy revealed by single mitochondrion sequencing (2018) (0)
Contributors to Volume 1 (1989) (0)
Biotechnology in clinical medicine (1987) (0)
Foreword by James H Eberwine PhD (2013) (0)
RNA analysis in neuronal dendrites: insights into Parkinson’s disease (2008) (0)
RNA Binding Protein Methods (2009) (0)
Astrocyte ethanol exposure reveals persistent and defined calcium response subtypes and associated gene signatures (2022) (0)
Transcription as a Target for Drug Development (1999) (0)
[17]In vitro assays for characterization of RNA-protein complexes involved in pro-opiomelanocortin mRNA translation (1996) (0)
Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution (2014) (0)
Multimodal single mouse and human cell ‘Omics: Is variability distinct across cellular modalities? (2018) (0)
Book Review:Gene Expression in Brain. Claire Zomzely-Neurath, William A. Walker (1986) (0)
Assessing characteristics of RNA amplification methods for single cell RNA sequencing (2016) (0)
RNA targeting, trafficking, and translation in dendrites (2007) (0)
cAMP Regulation of Transcription (1999) (0)
Molecular Biology Primer for Neurosurgeons (2011) (0)
List of contributors (2021) (0)
Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation (2015) (0)
Single cell/cellular subregion-targeted phototransfection. (2014) (0)
Abstract 16650: Transcriptional Profiling of Single Human Heart Cells Reveals Subtypes of Ventricular Cardiomyocytes (2016) (0)
Methods for image transfer ring of nucleic acid into living cells (2006) (0)
Cellular RNA Memory and the Sentinel RNA Hypothesis (2012) (0)
Molecular Neurobiology, Single‐Cell (2006) (0)
DNA sequence homologies of catecholamine enzymes (1984) (0)

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