James Eric Huff
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James Eric Huffmathematics Degrees
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Mathematics
James Eric Huff's Degrees
- PhD Biostatistics University of California, Berkeley
- Masters Statistics Stanford University
Why Is James Eric Huff Influential?
(Suggest an Edit or Addition)James Eric Huff's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Use of Historical Control Data in Carcinogenicity Studies in Rodents (1984) (335)
- Cadmium-induced Cancers in Animals and in Humans (2007) (325)
- Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure. (1985) (263)
- Carcinogenicity of 1,3-butadiene in C57BL/6 x C3H F1 mice at low exposure concentrations. (1990) (240)
- The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice. (1982) (224)
- Urolithiasis and bladder carcinogenicity of melamine in rodents. (1984) (212)
- Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice. (1989) (200)
- Evaluation of the carcinogenicity of chemicals: a review of the Monograph Program of the International Agency for Research on Cancer (1971 to 1977). (1978) (179)
- Carcinogenicity of TCDD: experimental, mechanistic, and epidemiologic evidence. (1994) (173)
- Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. (1997) (171)
- Neoplasms observed in untreated and corn oil gavage control groups of F344/N rats and (C57BL/6N X C3H/HeN)F1 (B6C3F1) mice. (1985) (168)
- Chemicals associated with site-specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents. (1991) (160)
- Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA) (2016) (151)
- Breast cancer and environmental risk factors: epidemiological and experimental findings. (1996) (149)
- Liver lesions in B6C3F1 mice: the National Toxicology Program, experience and position. (1987) (147)
- Carcinogenicity testing of phthalate esters and related compounds by the National Toxicology Program and the National Cancer Institute. (1982) (131)
- The impact of toxicity on carcinogenicity studies: implications for risk assessment. (1988) (125)
- Arsenic carcinogenesis in animals and in humans: Mechanistic, experimental, and epidemiological evidence (1997) (124)
- The carcinogenesis bioassay in perspective: application in identifying human cancer hazards. (1995) (122)
- Avoided and avoidable risks of cancer. (1997) (120)
- An evaluation of chemicals and industrial processes associated with cancer in humans based on human and animal data: IARC Monographs Volumes 1 to 20. (1980) (116)
- Scientific concepts, value, and significance of chemical carcinogenesis studies. (1991) (113)
- Benzene-induced Cancers: Abridged History and Occupational Health Impact (2007) (111)
- Carcinogenicity of p-chloroaniline in rats and mice. (1991) (98)
- Results from 86 two-year carcinogenicity studies conducted by the National Toxicology Program. (1984) (96)
- Sources of Variability in Rodent Carcinogenicity Studies (1989) (95)
- Long‐Term Chemical Carcinogenesis Bioassays Predict Human Cancer Hazards: Issues, Controversies, and Uncertainties (1999) (91)
- Species correlation in long-term carcinogenicity studies. (1987) (88)
- Comparative results of 327 chemical carcinogenicity studies. (1987) (86)
- Carcinogenesis Studies: Results of 398 Experiments on 104 Chemicals from the U. S. National Toxicology Program (1988) (85)
- Chemicals and cancer in humans: first evidence in experimental animals. (1993) (79)
- Chemically induced mammary gland cancer in the National Toxicology Program's carcinogenesis bioassay. (1995) (75)
- Is the human carcinogen arsenic carcinogenic to laboratory animals? (2000) (74)
- Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure. (1990) (71)
- The Limits of Two-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens (2008) (70)
- Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice. (1992) (69)
- Long-term chemical carcinogenesis experiments for identifying potential human cancer hazards: collective database of the National Cancer Institute and National Toxicology Program (1976-1991). (1991) (67)
- Comparative toxicity and carcinogenicity of two chlorinated paraffins in F344/N rats and B6C3F1 mice. (1987) (60)
- Alleged ‘misconceptions’ distort perceptions of environmental cancer risks (2001) (60)
- Cellular and molecular mechanisms of hormonal carcinogenesis. Environmental influences. (1996) (59)
- Occurrence and relevance of chemically induced benign neoplasms in long-term carcinogenicity studies (1989) (59)
- Toxicology and carcinogenesis studies of two grades of pentachlorophenol in B6C3F1 mice. (1991) (58)
- 1,3-Butadiene: toxicity and carcinogenicity in laboratory animals and in humans. (1992) (58)
- The Secret History of the War on Cancer (2008) (57)
- Styrene exposure and risk of cancer. (2011) (54)
- Carcinogenesis bioassays: study duration and biological relevance. (2001) (51)
- Liver Carcinogenesis is Not a Predicted Outcome of Chemically Induced Hepatocyte Proliferation (1993) (47)
- Carcinogenesis studies of 4,4'-methylenedianiline dihydrochloride given in drinking water to F344/N rats and B6C3F1 mice. (1986) (47)
- Mechanisms, chemical carcinogenesis, and risk assessment: cell proliferation and cancer. (1995) (46)
- Comparison of site-specific and overall tumor incidence analyses for 81 recent National Toxicology Program carcinogenicity studies. (1986) (46)
- Chemicals Studied and Evaluated in Long‐Term Carcinogenesis Bioassays by Both the Ramazzini Foundation and the National Toxicology Program (2002) (45)
- IARC Monographs, Industry lnfluence, and upgrading, Downgrading, and Under-grading Chemicals: A Personal Point of View (2002) (45)
- Comparative chronic toxicities and carcinogenic potentials of 2-ethylhexyl-containing compounds in rats and mice. (1985) (44)
- Long-term carcinogenesis studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin and hexachlorodibenzo-p-dioxins (2004) (42)
- Chronic effects of agar, guar gum, gum arabic, locust-bean gum, or tara gum in F344 rats and B6C3F1 mice. (1983) (39)
- The carcinogenicity of di(2-ethylhexyl) phthalate (DEHP) in perspective. (1983) (39)
- Chemicals and industrial processes associated with cancer in humans. IARC Monographs, Volumes 1 to 20. (1979) (39)
- Two-year inhalation carcinogenesis studies of methyl methacrylate in rats and mice: inflammation and degeneration of nasal epithelium. (1988) (37)
- Industry Influence on Occupational and Environmental Public Health (2007) (36)
- Cell proliferation and chemical carcinogenesis: symposium overview. (1993) (36)
- Issues and controversies surrounding qualitative strategies for identifying and forecasting cancer causing agents in the human environment. (1993) (35)
- No evidence of carcinogenicity of D-mannitol and propyl gallate in F344 rats or B6C3F1 mice. (1986) (34)
- Cellular and molecular mechanisms of chemically induced renal carcinogenesis. (1991) (34)
- Absence of morphologic correlation between chemical toxicity and chemical carcinogenesis. (1993) (34)
- Toxicity and carcinogenicity of nitrofurazone in F344/N rats and B6C3F1 mice. (1989) (34)
- Carcinogenicity of bisphenol-A in Fischer rats and B6C3F1 mice (2001) (33)
- Long-term toxicology and carcinogenicity of 2,4,6-trichlorophenol. (2012) (32)
- Benzyl acetate carcinogenicity, metabolism, and disposition in Fischer 344 rats and B6C3F1 mice. (1985) (31)
- Chronic Kidney Disease and Organic Chemical Exposures: Evaluations of Causal Relationships in Humans and Experimental Animals (1984) (31)
- Inhalation Toxicology and Carcinogenesis Studies of Methylene Chloride (Dichloromethane) in F344/N Rats and B6C3F1 Mice (1988) (31)
- Value of Historical Control Data and Other Issues Related to the Evaluation of Long-Term Rodent Carcinogenicity Studies (1997) (29)
- Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice 1. Hydrochlorothiazide (1990) (28)
- Carcinogenesis Studies of Dichlorvos in Fischer Rats and B6C3F1 Mice (1991) (28)
- 2,3,7,8-TCDD: A potent & complete carcinogen in experimental animals (1992) (27)
- Evolution of cancer etiology and primary prevention. (2001) (26)
- Sawmill chemicals and carcinogenesis. (2001) (26)
- Carcinogenesis Studies of Benzene, Methyl Benzene, and Dimethyl Benzenes (1988) (26)
- 1,3-Butadiene induces cancer in experimental animals at all concentrations from 6.25 to 8000 parts per million. (1993) (25)
- IARC monographs, industry influence, and upgrading, downgrading, and under-grading chemicals: a personal point of view. International Agency for Research on Cancer. (2002) (24)
- Carcinogenicity of 1,3-butadiene. (1993) (24)
- Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice 2. Furosemide (1990) (24)
- Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice. (1988) (23)
- Evolution of Research in Cancer Etiology (2002) (22)
- Cell proliferation and chemical carcinogenesis: a symposium overview. (1993) (22)
- Inhalation of tetranitromethane causes nasal passage irritation and pulmonary carcinogenesis in rodents. (1991) (22)
- Design strategies, results and evaluations of long-term chemical carcinogenesis studies. (1992) (21)
- Carcinogenicity bioassays of bisphenol A, 4-vinylcyclohexene diepoxide, and 4-vinycyclohexene. (2001) (21)
- The carcinogenic activity of commercial grade toluene diisocyanate in rats and mice in relation to the metabolism of the 2,4- and 2,6-TDI isomers. (1990) (21)
- Carcinogenicity of TCDD in Laboratory Animals: Implications for Risk Assessment (1993) (21)
- Chronic toxicology and carcinogenesis studies of Telone II by gavage in Fischer-344 rats and B6C3F1 mice. (1986) (20)
- The IARC evaluation of DEHP excludes key papers demonstrating carcinogenic effects. (2003) (20)
- Carcinogenesis bioassay results from the National Toxicology Program. (1982) (20)
- Animal and human carcinogens. (1999) (20)
- Weight of evidence versus weight of speculation to evaluate the alpha2u-globulin hypothesis. (1997) (20)
- Predictive Strategies for Selecting 379 NCI/NTP Chemicals Evaluated for Carcinogenic Potential: Scientific and Public Health Impact (1993) (20)
- Frequent p53 and H-ras Mutations in Benzene- and Ethylene Oxide-Induced Mammary Gland Carcinomas from B6C3F1 Mice (2006) (20)
- Phthalate esters carcinogenicity in F344/N rats and B6C3F1 mice. (1984) (20)
- Reserpine-induced cell transformation without detectable genetic effects in Syrian hamster embryo cells in culture. (1994) (20)
- Multicomponent criteria for predicting carcinogenicity: dataset of 30 NTP chemicals. (1996) (19)
- Toxicity and carcinogenicity of rotenone given in the feed to F344/N rats and B6C3F1 mice for up to two years. (1988) (19)
- Effects of testosterone, testosterone propionate, 17 beta-trenbolone and progesterone on cell transformation and mutagenesis in Syrian hamster embryo cells. (1995) (19)
- Perspective and overview of the concepts and value of hazard identification as the initial phase of risk assessment for cancer and human health. (1992) (19)
- Chemical toxicity and chemical carcinogenesis. Is there a causal connection? A comparative morphological evaluation of 1500 experiments. (1992) (19)
- Refinement of long-term toxicity and carcinogenesis studies☆ (1990) (18)
- Evidence of carcinogenicity of DDT in nonhuman primates (2000) (18)
- Predictive strategies for selecting 379 NCI/NTP chemicals evaluated for carcinogenic potential: scientific and public health impact. (1993) (18)
- Dioxins and Mammalian Carcinogenesis (1994) (18)
- Carcinogenicity of 1,3-butadiene (1992) (18)
- Carcinogenicity of ochratoxin A in experimental animals. (1991) (17)
- Absence of Carcinogenic Activity in Fischer Rats and B6C3F1 Mice Following 103-Week Inhalation Exposures to Toluene (2003) (17)
- Does exposure to bisphenol A represent a human health risk? (2003) (17)
- Carcinogenesis Bioassay of Propyl Gallate in F344 Rats and B6C3FJ Mice (1983) (17)
- Chronic Toxkity Results and Ongoing Studies of 1,3‐Butadiene by the National Toxicology Program (1988) (16)
- Malathion and malaoxon: histopathology reexamination of the National Cancer Institute's carcinogenesis studies. (1985) (16)
- Clarifying carcinogenicity of ethylbenzene. (2010) (16)
- Symposium Overview: Toxicology, Carcinogenesis, and Human Health Aspects of 1,3-Butadiene (1990) (16)
- Toxicity and carcinogenicity studies of nalidixic acid in rodents. (1991) (16)
- Toxicology and carcinogenesis studies of isophorone in F344 rats and B6C3F1 mice. (1986) (16)
- High Frequency of Ras Mutations in Forestomach and Lung Tumors of B6C3F1 Mice Exposed to 1-Amino-2,4-dibromoanthraquinone for 2 Years (2001) (15)
- Neurotoxicity and carcinogenicity of N-methylolacrylamide in F344 rats and B6C3F1 mice. (1990) (15)
- Aspartame Bioassay Findings Portend Human Cancer Hazards (2007) (15)
- Trichloroethylene and cancers in humans. (2004) (14)
- No evidence of carcinogenicity for L-ascorbic acid (vitamin C) in rodents. (1984) (14)
- Carcinogenicity of bisphenol A revisited. (2002) (13)
- Lorenzo Tomatis and primary prevention of environmental cancer (2011) (13)
- NTP Toxicology and Carcinogenesis Studies of Toluene (CAS No.108-88-3) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). (1990) (13)
- Hormonal carcinogenesis and environmental influences: background and overview. (1996) (13)
- IARC and the DEHP Quagmire (2003) (12)
- Predicting chemicals causing cancer in animals as human carcinogens (2010) (12)
- A historical perspective on the classification developed and used for chemical carcinogens by the National Toxicology Program during 1983-1992. (1992) (12)
- Comparative Toxicity and Carcinogenicity Studies of Tetracycline and Oxytetracycline in Rats and Mice (1991) (12)
- Chemically exacerbated chronic progressive nephropathy not associated with renal tubular tumor induction in rats: an evaluation based on 60 carcinogenicity studies by the national toxicology program. (2012) (11)
- Arsenic carcinogenicity testing. (1998) (11)
- Primary prevention of cancer. (2011) (11)
- Response: alpha-2-mu-Globulin Nephropathy, Posed Mechanisms, and White Ravens. (1996) (11)
- Forestomach lesions in rats and mice administered 3-chloro-2-methylpropene by gavage for two years. (1986) (11)
- Two-year toxicity and carcinogenicity studies of ampicillin trihydrate and penicillin VK in rodents. (1989) (10)
- Inhalation toxicity and carcinogenesis studies of methylene chloride (dichloromethane) in F344/N rats and B6C3F1 mice. (1988) (10)
- On the proportion of positive results in carcinogenicity studies in animals. (1985) (10)
- Cyanide removal from refinery wastewater using powdered activated carbon (1980) (9)
- Toxicologic and carcinogenic effects of inhaled tetrachloroethylene in rats and mice. (1986) (9)
- Antitumor effects of THC. (2000) (9)
- Chemically induced cancers in hormonal organs of laboratory animals and of humans. (1996) (9)
- Cellular and molecular mechanisms of hormonal carcinogenesis (1996) (9)
- Declaring chemicals "not carcinogenic to humans" requires validation, not speculation. (2003) (9)
- No evidence of toxicity or carcinogenicity of pentaerythritol tetranitrate given in the diet to F344 rats and B6C3F1 mice for up to two years (1990) (9)
- Dermal toxicity and carcinogenicity of 4-vinyl-1-cyclohexene diepoxide in Fischer rats and B6C3F1 mice. (1990) (8)
- Liver Carcinogencsis by Methyl Carbamate in F344 Rats and Not in B6C3F1 Mice (1992) (8)
- Chronic kidney disease and organic chemical exposures: evaluations of causal relationships in humans and experimental animals. (1984) (8)
- Biological issues in extrapolation (1989) (8)
- More Toxin Tests Needed (2008) (8)
- An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays (2016) (8)
- Re: Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. (1999) (8)
- Multi-Organ Carcinogenicity of 3,3′-Dimethoxybenzidine Dihydrochloride Given in Drinking Water to F344/N Rats (1990) (8)
- Two-year toxicity and carcinogenicity studies of ampicillin trihydrate and penicillin VK in rodents (1989) (7)
- Carcinogenesis studies in rodents for evaluating risks associated with chemical carcinogens in aquatic food animals. (1991) (7)
- REFINERY CYANIDES: A REGULATORY DILEMMA (1979) (7)
- Chemicals associated with tumours of the kidney, urinary bladder and thyroid gland in laboratory rodents from 2000 US National Toxicology Program/National Cancer Institute bioassays for carcinogenicity. (1999) (7)
- War on Carcinogens: Industry Disputes Human Relevance of Chemicals Causing Cancer in Laboratory Animals Based on Unproven Hypotheses, Using Kidney Tumors as an Example (2013) (6)
- Testing toxic pesticides in humans: health risks with no health benefits. (2004) (6)
- Di(2-ethylhexyl) adipate: Condensation of the Carcinogenesis Bioassay Technical Report. (1982) (6)
- Re: Arsenic - Evidence of Carcinogenicity in Animals. (1998) (6)
- Re: Long-term toxicity and carcinogenicity study of cyclamate in nonhuman primates (Takayama et al., Toxicol. Sci. 53, 33-39) (2000) (6)
- Comparative toxicity and carcinogenicity studies of tetracycline and oxytetracycline in rats and mice. (1991) (6)
- Refinement of Long-Term Toxicity and Carcinogenesis Studies1 (1990) (6)
- Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol-. Certain health supplements may cause both carcinogenic and anticarcinogenic effects. (2002) (6)
- Application of emulsified zero-valent iron: Four full-scale remediation sites (2011) (5)
- Toxicology and Carcinogenicity of 1,3-Butadiene (1989) (5)
- Industry Influences IARC Carcinogenesis Evaluations (2003) (4)
- The effects of allyl isovalerate on the hematopoietic and immunologic systems in rodents. (1988) (4)
- Thirteen-week toxicology studies of 1-amino-2,4-dibromoanthraquinone in Fischer 344/N rats and B6C3F1 mice. (1986) (4)
- Carcinogenic Hazards from Eating Fish and Shellfish Contaminated with Disparate and Complex Chemical Mixtures (1994) (4)
- Carcinogenesis bioassay in rats and mice fed diets containing 2-biphenylamine hydrochloride. (1982) (4)
- Caprolactam: Condensations of the Carcinogenesis Bioassay Technical Reports. (1982) (4)
- Forestomach neoplasms in Fischer F344/N rats and B6C3F1 mice exposed to diglycidyl resorcinol ether--an epoxy resin. (1990) (4)
- Comparative carcinogenicity of two structurally similar phenylenediamine dyes (HC blue no. 1 and HC blue no. 2) in F344/N rats and B6C3F1 mice. (1989) (3)
- Toxicity and carcinogenicity studies of phenylephrine hydrochloride in F344/N rats and B6C3F1 mice. (1988) (3)
- Hexane Fraction of American Ginseng Suppresses Colitis and Colon Cancer—Letter (2012) (3)
- David Rall and the National Toxicology Program (2005) (3)
- Shortcomings of rodent carcinogenicity studies. (1983) (3)
- Carcinogenicity and pesticides: Biological issues in extrapolation (1989) (2)
- Lesions of the Urinary Tract Produced in Fischer 344 Rats and B6C3F1 Mice After Chronic Administration of 11-Aminoundecanoic Acid (1983) (2)
- Environmental Justice and Primary Prevention of Cancer: The Odyssey and Legacy of Lorenzo Tomatis (2012) (2)
- MtBE and cancer in animals: statistical issues with poly-3 survival adjustments for lifetime studies. (2008) (2)
- Leukemia induced in rats but not mice by dimethyl morpholinophosphoramidate, a simulant anticholinesterase agent. (1994) (2)
- Occupational cancer and social inequities. (2011) (2)
- Condensations of the Carcinogenesis Bioassay Technical Reports. (1982) (1)
- Re: Journal to encourage analysis by sex/ethnicity. (2001) (1)
- Erratum: “An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays” (2017) (1)
- Is marihuana [THC] anti-carcinogenic? (2005) (1)
- FD&C Yellow No. 6. Condensation of the Carcinogenesis Bioassay Technical Report. (1982) (1)
- Arsenic : Evidence of Carcinogenicity in Animals (2006) (1)
- The role of environmental factors in the pathogenesis of breast cancer (2001) (1)
- Letters to the Editor (1991) (1)
- Longer Rodent Bioassay: Huff et al. Respond (2008) (1)
- as human carcinogens Predicting chemicals causing cancer in animals (2010) (0)
- Re: Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. (2004) (0)
- Evolution of Cancer Etiology and Primary Prevention: Primary Prevention Aimed at Avoiding or Drastically Reducing Exposures Will Be the Most Efficient Way to Prevent Environmentally Associated Cancers. (Perspectives Editorial) (2001) (0)
- LETTER TO THE EDITOR Long-term Cancer Bioassays of Ascorbic Acid (2008) (0)
- Occupational Chemical Carcinogenesis (2012) (0)
- The role of environmental factors in the pathogenesis of breast cancer. Discussion (2001) (0)
- Cyclophosphamide in chronic active hepatitis. (1979) (0)
- Feasibility of a central recovery facility for the metal finishing industry in Cook County (1986) (0)
- Long-term cancer bioassays of ascorbic acid. (2008) (0)
- Cytembena: Condensation of the Carcinogenesis Bioassay Technical Report. (1982) (0)
- An Evaluationof Chemicalsand IndustrialProcessesAssociatedwith Cancerin HumansBasedon Humanand AnimalData:IARCMonographs Volumes1 to 201 (1980) (0)
- Accidental gynecomastia in children. Discussion (2001) (0)
- Economic Impact Analysis of Combined Sewer Overflow Regulations on East St. Louis, R81-12 (2017) (0)
- Causes of juvenile obesity : Clues from epidemiology. Discussion (2001) (0)
- 3 Carcinogenicity (1996) (0)
- His gifts to humanity are well recognized in saved lives and a cadre of scientists influenced by his magnanimity, honesty, sense of ethics, and moral character. (2008) (0)
- Di(2-ethylhexyl) Adipate: Condensation of the Carcinogenesis Bioassay (2016) (0)
- Lesions of the urinary tract produced in Fischer 344 rats and B6C3F1 mice after chronic administration of 11-aminoundecanoic acid. (1983) (0)
- Mourning dove differential use of reclaimed surface-mined lands in east-central Texas (2001) (0)
- Environmental management/Refinery cyanides: a regulatory dilemma (1978) (0)
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