James M. Berger
#72,270
Most Influential Person Now
American biophysicist and biophysical chemist
James M. Berger's AcademicInfluence.com Rankings
James M. Bergerchemistry Degrees
Chemistry
#2428
World Rank
#3336
Historical Rank
#733
USA Rank
Organic Chemistry
#514
World Rank
#594
Historical Rank
#105
USA Rank

James M. Bergerphysics Degrees
Physics
#4541
World Rank
#6223
Historical Rank
#1501
USA Rank
Biophysics
#143
World Rank
#153
Historical Rank
#34
USA Rank

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Chemistry Physics
James M. Berger's Degrees
- PhD Biophysics Stanford University
- Masters Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is James M. Berger Influential?
(Suggest an Edit or Addition)According to Wikipedia, James Michael Berger is an American academic working as a professor of biophysics and biophysical chemistry at Johns Hopkins University School of Medicine, where he is also the co-director of the Cancer Chemical and Structural Biology Program at the Sidney Kimmel Comprehensive Cancer Center and the director of the Johns Hopkins Institute for Basic Biomedical Sciences. His main area of research is the functions of molecular cellular machinery.
James M. Berger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Core Structure of gp41 from the HIV Envelope Glycoprotein (1997) (1481)
- Structure and mechanism of DNA topoisomerase II (1996) (750)
- Evolutionary relationships and structural mechanisms of AAA+ proteins. (2006) (721)
- Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. (2005) (663)
- Neurexin mediates the assembly of presynaptic terminals (2003) (583)
- All tangled up: how cells direct, manage and exploit topoisomerase function (2011) (508)
- A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion (2002) (470)
- DNA topoisomerases: harnessing and constraining energy to govern chromosome topology (2008) (409)
- Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases. (2004) (383)
- DNA replication initiation: mechanisms and regulation in bacteria (2007) (355)
- Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. (1994) (347)
- The structural basis for MCM2–7 helicase activation by GINS and Cdc45 (2011) (329)
- Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module (1997) (321)
- Running in Reverse: The Structural Basis for Translocation Polarity in Hexameric Helicases (2009) (296)
- Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling (2006) (280)
- Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity. (2013) (277)
- Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis. (2006) (273)
- Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export (2006) (271)
- Structural basis for gate-DNA recognition and bending by type IIA topoisomerases (2007) (260)
- Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control. (2000) (244)
- Structure of the Rho Transcription Terminator Mechanism of mRNA Recognition and Helicase Loading (2003) (243)
- The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation (2002) (229)
- The protective antigen component of anthrax toxin forms functional octameric complexes. (2009) (221)
- A conserved mechanism of DEAD-box ATPase activation by nucleoporins and IP6 in mRNA export (2011) (220)
- Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 (2003) (218)
- Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot (1999) (217)
- Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. (1997) (196)
- Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. (2015) (187)
- The Polar T1 Interface Is Linked to Conformational Changes that Open the Voltage-Gated Potassium Channel (2000) (186)
- Mechanisms for initiating cellular DNA replication. (2013) (183)
- The structure of DNA-bound human topoisomerase II alpha: conformational mechanisms for coordinating inter-subunit interactions with DNA cleavage. (2012) (181)
- DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. (1996) (173)
- The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2. (2004) (169)
- A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination. (2006) (162)
- The structural basis for substrate specificity in DNA topoisomerase IV. (2005) (154)
- The N-terminal domain of Nup159 forms a beta-propeller that functions in mRNA export by tethering the helicase Dbp5 to the nuclear pore. (2004) (154)
- Structure and Function of the Conserved Core of Histone Deposition Protein Asf1 (2003) (153)
- Structure of the RNA polymerase domain of E. coli primase. (2000) (151)
- Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11 (1999) (151)
- A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases (2010) (147)
- Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands (1999) (146)
- Mechanisms for initiating cellular DNA replication (2017) (144)
- Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis (2016) (141)
- Replication Origin Recognition and Deformation by a Heterodimeric Archaeal Orc1 Complex (2007) (137)
- DNA stretching by bacterial initiators promotes replication origin melting (2011) (132)
- The C-terminal domain of DNA gyrase A adopts a DNA-bending β-pinwheel fold (2004) (127)
- Mechanisms and regulation of DNA replication initiation in eukaryotes (2017) (125)
- The structural basis for terminator recognition by the Rho transcription termination factor. (1999) (125)
- Structural Synergy and Molecular Crosstalk between Bacterial Helicase Loaders and Replication Initiators (2008) (121)
- The nuts and bolts of ring-translocase structure and mechanism. (2011) (120)
- DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome (2014) (118)
- Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity (2012) (115)
- Recent advances in understanding structure-function relationships in the type II topoisomerase mechanism. (2005) (113)
- Structural Insights into RNA-Dependent Ring Closure and ATPase Activation by the Rho Termination Factor (2006) (111)
- Crosstalk between primase subunits can act to regulate primer synthesis in trans. (2005) (109)
- Crystal Structure of the Eukaryotic Origin Recognition Complex (2015) (107)
- Structural similarities between topoisomerases that cleave one or both DNA strands. (1998) (103)
- Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity (2014) (103)
- Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction (2010) (102)
- Identification of Residues in Yeast Spo11p Critical for Meiotic DNA Double-Strand Break Formation (2002) (101)
- Structure of DNA topoisomerases. (1998) (101)
- Recent developments in DNA topoisomerase II structure and mechanism. (1996) (100)
- Suite of three protein crystallography beamlines with single superconducting bend magnet as the source. (2004) (96)
- Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis (2004) (95)
- Structure of the topoisomerase VI‐B subunit: implications for type II topoisomerase mechanism and evolution (2003) (93)
- Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex (2006) (88)
- The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker (2013) (87)
- Nanoscale protein assemblies from a circular permutant of the tobacco mosaic virus. (2010) (86)
- Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement (2015) (82)
- Fluoroquinolone-Gyrase-DNA Complexes (2014) (82)
- On the simultaneous binding of eukaryotic DNA topoisomerase II to a pair of double-stranded DNA helices. (1993) (80)
- Crystal structure of the N-terminal domain of the DnaB hexameric helicase. (1999) (80)
- Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI (2007) (80)
- Computational learning reveals coiled coil-like motifs in histidine kinase linker domains (1998) (79)
- Regulation of bacterial priming and daughter strand synthesis through helicase-primase interactions (2006) (78)
- Origin Remodeling and Opening in Bacteria Rely on Distinct Assembly States of the DnaA Initiator (2010) (78)
- The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins (2005) (77)
- Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II (2019) (77)
- Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl‐2 (2007) (74)
- Type II DNA topoisomerases. (1998) (74)
- Structure of the yeast histone H3-ASF1 interaction: implications for chaperone mechanism, species-specific interactions, and epigenetics (2006) (72)
- THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves (2009) (72)
- ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote (2012) (71)
- Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase (2016) (68)
- Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D* (2006) (68)
- Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases. (2012) (66)
- A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions (2015) (66)
- A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function (2010) (65)
- Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation (2009) (64)
- AAA+ ATPases in the initiation of DNA replication. (2008) (64)
- Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI. (2005) (64)
- The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks (2011) (63)
- Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array (2015) (63)
- The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. (2004) (61)
- Interdomain Communication of the Chd1 Chromatin Remodeler across the DNA Gyres of the Nucleosome. (2017) (61)
- A new class of disordered elements controls DNA replication through initiator self-assembly (2019) (61)
- Function and Structure of a Prokaryotic Formylglycine-generating Enzyme*S⃞ (2008) (61)
- Identification of a DNA primase template tracking site redefines the geometry of primer synthesis (2008) (60)
- Biochemical characterization of Cdc6/Orc1 binding to the replication origin of the euryarchaeon Methanothermobacter thermoautotrophicus. (2004) (59)
- ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA (2012) (57)
- Structural Elucidation and Functional Characterization of the Hyaloperonospora arabidopsidis Effector Protein ATR13 (2011) (55)
- Structural frameworks for considering microbial protein‐ and nucleic acid‐dependent motor ATPases (2008) (55)
- AAA+ ATPases in the Initiation of DNA Replication (2008) (54)
- Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin. (2005) (54)
- Mechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs (2012) (53)
- Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein. (2018) (53)
- Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome (2019) (52)
- How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II topoisomerases. (2009) (50)
- Structure of the ATP‐binding domain of Plasmodium falciparum Hsp90 (2010) (50)
- Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing (2011) (50)
- Biosynthesis of poly(γ-glutamylcysteinyl)glycines in cadmium-tolerant Datura innoxia (Mill.) cells (1988) (49)
- Nucleotide and partner-protein control of bacterial replicative helicase structure and function. (2013) (48)
- Structural and Computational Characterization of the SHV-1 β-Lactamase-β-Lactamase Inhibitor Protein Interface* (2006) (46)
- A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation (2013) (46)
- Molecular basis for G protein control of the prokaryotic ATP sulfurylase. (2006) (46)
- Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design (2014) (45)
- A structural framework for replication origin opening by AAA+ initiation factors. (2013) (45)
- Molecular determinants of origin discrimination by Orc1 initiators in archaea (2011) (44)
- High throughput crystallography of TB drug targets. (2007) (42)
- The crystal structure of the hinge domain of the Escherichia coli structural maintenance of chromosomes protein MukB. (2010) (42)
- The role of DNA bending in type IIA topoisomerase function (2013) (42)
- Divalent metal cofactor binding in the kinetic folding trajectory of Escherichia coli ribonuclease HI (2000) (42)
- Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor (2016) (41)
- Resveratrol: A novel type of topoisomerase II inhibitor (2017) (40)
- SnapShot: Nucleic Acid Helicases and Translocases (2008) (39)
- Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface. (2008) (38)
- Structure of the C-terminus of the mRNA export factor Dbp5 reveals the interaction surface for the ATPase activator Gle1 (2009) (38)
- Crystal structure of the DNA gyrase GyrA N‐terminal domain from Mycobacterium tuberculosis (2010) (37)
- Loading strategies of ring-shaped nucleic acid translocases and helicases. (2014) (37)
- Structural basis for topoisomerase VI inhibition by the anti-Hsp90 drug radicicol (2006) (35)
- Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA. (2019) (35)
- Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity (2019) (34)
- Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization (2012) (33)
- Contributions of folding cores to the thermostabilities of two ribonucleases H (2002) (32)
- Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. (2009) (32)
- Mechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs (2012) (32)
- Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å (2005) (30)
- Emerging roles for plant topoisomerase VI. (2003) (30)
- Structural basis for the MukB‐topoisomerase IV interaction and its functional implications in vivo (2013) (29)
- Ligand-induced and small-molecule control of substrate loading in a hexameric helicase (2016) (28)
- An Atypical AAA+ ATPase Assembly Controls Efficient Transposition through DNA Remodeling and Transposase Recruitment (2015) (27)
- Unraveling the early steps of prokaryotic replication. (2005) (27)
- Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase. (2004) (26)
- Conformational control and DNA-binding mechanism of the metazoan origin recognition complex (2018) (25)
- Lethal synergy involving bicyclomycin: an approach for reviving old antibiotics. (2014) (24)
- DNA replication: making two forks from one prereplication complex. (2010) (23)
- A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs (2010) (22)
- Structural and functional characterization of the Spo11 core complex (2020) (22)
- IOTA: integration optimization, triage and analysis tool for the processing of XFEL diffraction images1 (2016) (20)
- The role of ATP-dependent machines in regulating genome topology. (2016) (20)
- Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons. (2018) (20)
- Genetic dissection of pancreatic trypsin inhibitor. (1992) (18)
- Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface. (2006) (17)
- Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV. (2013) (17)
- Primus inter pares (First among equals) (2001) (17)
- DNA replication at high resolution. (2000) (16)
- Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein (2014) (16)
- Topoisomerase VI senses and exploits both DNA crossings and bends to facilitate strand passage (2018) (15)
- Real-time detection of DNA topological changes with a fluorescently labeled cruciform (2013) (15)
- FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studies. (2007) (15)
- Hyperthermophilic Aquifex aeolicus initiates primer synthesis on a limited set of trinucleotides comprised of cytosines and guanines (2008) (14)
- Dynamic coupling between conformations and nucleotide states in DNA gyrase (2018) (14)
- Structural Mechanisms for Replicating DNA in Eukaryotes. (2021) (14)
- Garcinol and Related Polyisoprenylated Benzophenones as Topoisomerase II Inhibitors: Biochemical and Molecular Modeling Studies. (2019) (14)
- Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity. (2019) (13)
- Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication (2016) (13)
- Enzymes that push DNA around (1999) (12)
- Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast (2020) (12)
- Mechanisms of hexameric helicases (2021) (12)
- A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome (2018) (11)
- Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase (2017) (11)
- Erratum: Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 (Proceedings of the National Academy of Sciences of the United States of America (September 16, 2003) 100:19 (10629-10634)) (2003) (11)
- DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus. (2014) (10)
- Erratum: Structure and mechanism of DNA topoisomerase II (1996) (9)
- Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis (2022) (9)
- Chapter 10:Structure and Function of DNA Topoisomerases (2008) (8)
- Tuning the sequence specificity of a transcription terminator (2019) (8)
- Ligand-induced and small molecule control of substrate loading in a hexameric helicase (2016) (8)
- Synthesis and antimicrobial evaluation of new nitric oxide‐donating fluoroquinolone/oxime hybrids (2020) (8)
- Precursor-product relationships of Poly(γ-glutamylcysteinyl)glycine biosynthesis in Datura innoxia (1989) (7)
- New fluoroquinolones/nitric oxide donor hybrids: design, synthesis and antitubercular activity (2019) (7)
- The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader (2020) (7)
- Synthesis, molecular docking, antimicrobial evaluation, and DNA cleavage assay of new thiadiazole/oxadiazole ciprofloxacin derivatives (2019) (7)
- Crystallization and X-ray structure determination of an RNA-dependent hexameric helicase. (2012) (7)
- A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents (2019) (6)
- Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites (2021) (5)
- Toward computational design of protein crystals with improved resolution (2019) (5)
- Convergent evolution in two bacterial replicative helicase loaders. (2022) (5)
- Crystal Structure of the N-terminal Domain of Nup159 (2004) (3)
- Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites. (2021) (3)
- Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase (2020) (3)
- Structure of topoisomerase subunit (2003) (3)
- Molecular determinants of phase separation for Drosophila DNA replication licensing factors (2021) (3)
- Structural and Biochemical Characterization of the Interaction between KPC-2 β -Lactamase and β -Lactamase Inhibitor Protein, (2009) (3)
- Nucleotide-bound structures of the DnaG catalytic core reveal how metal•NTP substrates are bound during primer synthesis and blocked by stringent response alarmones (2012) (3)
- Crystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazei (2007) (2)
- Molecular mechanisms of substrate-controlled ring dynamics and sub-stepping in a nucleic-acid dependent hexameric motor (2016) (2)
- FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN (1997) (2)
- Structural Basis for the MukB-topoisomerase IV Interaction (2013) (2)
- Structural and functional characterization of the Spo11 core complex (2021) (2)
- Protein–nucleic acid interactions: some assembly required (2007) (1)
- The Crystal Structure of the Dimerization Domain of Escherichia coli Structural Maintenance of Chromosomes Protein MukB (2010) (1)
- STRUCTURE OF THE DNA TOPOISOMERASE VI A SUBUNIT (1999) (1)
- Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II (2003) (1)
- Author response: Topoisomerase VI senses and exploits both DNA crossings and bends to facilitate strand passage (2018) (1)
- A Fluorescent Assay to Monitor Ligand-Dependent Closure of the Hexameric Rho Helicase Ring. (2021) (1)
- Author response: Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication (2016) (1)
- S. cerevisiae Dbp5 bound to RNA and ADP BeF3 (2011) (0)
- Topoisomerase VI-B, ADP-bound monomer form (2005) (0)
- Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340 (2007) (0)
- The structure of the S. aureus DnaG RNA Polymerase Domain (2012) (0)
- SURVEY AND SUMMARY The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks (2011) (0)
- Hydrocinnamic acid-bound structure of SRHEPT mutant of E. coli aspartate aminotransferase (2004) (0)
- TOPOISOMERASE RESIDUES 410-1202, (1996) (0)
- Crystal Structure of a GTP-Regulated ATP Sulfurylase Heterodimer from Pseudomonas syringae (2006) (0)
- Crystal structure of the DnaC helicase loader (2008) (0)
- Crystal Structure of MukF(1-287) (2005) (0)
- Hydrocinnamic acid-bound structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase (2004) (0)
- RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX (1999) (0)
- E. coli DnaBC apo complex (2019) (0)
- S. cerevisiae Dbp5 L327V bound to Nup159, Gle1 H337R, IP6 and ADP (2011) (0)
- Crystal structure of the DnaC helicase loader in complex with ADP-BeF3 (2008) (0)
- X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA (2003) (0)
- Mechanism for the Regulated Control of Transcription Termination by a Universal Adapter Protein (2018) (0)
- Structure of the full-length E. coli ParC subunit (2005) (0)
- Etoposide promotes DNA loop trapping and barrier formation by topoisomerase II (2023) (0)
- Crystal Structure of the SHV D104K Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex (2006) (0)
- Tuning the sequence specificity of a transcription terminator (2019) (0)
- Aquifex aeolicus type IIA topoisomerase C-terminal domain (2010) (0)
- Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) (2009) (0)
- Crystal structure of the catalytic subunit of yeast primase (2013) (0)
- Crystal structure of the THAP domain from D. melanogaster P-element transposase in complex with its natural DNA binding site (2009) (0)
- Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains) (2005) (0)
- Rho transcription termination factor bound to RNA and ADP-BeF3 (2009) (0)
- Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis (2005) (0)
- Structure of the E. Coli Gyrase DNA Binding and Cleavage Core Reveals A Unique Domain (2010) (0)
- TOPOISOMERASE II RESIDUES 409-1201 (1999) (0)
- The closed ring structure of the Rho transcription termination factor in complex with nucleic acid in the motor domains (2006) (0)
- Crystal structure of Staphylococcal nuclease variant Delta+PHS Q123D at cryogenic temperature (2019) (0)
- 1 Molecular determinants of phase separation for Drosophila DNA replication licensing factors 1 2 (2021) (0)
- Dimensional Reduction for Single-Molecule Imaging of DNA and Nucleosome Condensation by Polyamines, HP1α and Ki-67 (2023) (0)
- Structure of the DnaG primase catalytic domain bound to ssDNA (2008) (0)
- Crystal structure of Staphylococcal nuclease variant Delta+PHS K127L at cryogenic temperature (2019) (0)
- CRYSTAL STRUCTURE OF DNA REPLICATION INITIATION FACTOR (2002) (0)
- Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H (2002) (0)
- Structure and Mechanism of Eukaryotic Type IIA Topoisomerases (2012) (0)
- Unexpected Sophistication and Complexity of Chemomechanical Control Linkages in Nucleic Acid Motor (2012) (0)
- Faculty Opinions recommendation of Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU. (2001) (0)
- Rho transcription termination factor bound to rA7 and 6 ADP-BeF3 molecules (2016) (0)
- Two surfaces on Rtt106 mediate histone binding and chaperone activity (2011) (0)
- The N-Terminal Domain of Nup 159 Forms a-Propeller that Functions in mRNA Export by Tethering the Helicase Dbp (2004) (0)
- Crystal structure of the IstB AAA+ domain bound to ADP-BeF3 (2015) (0)
- Bacterial initiation protein (2016) (0)
- Mechanisms and Functional Diversity of Macromolecular Remodeling by ATP-Dependent Motors. (2016) (0)
- Maleic acid-bound structure of SRHEPT mutant of E. coli aspartate aminotransferase (2004) (0)
- Editor's evaluation: Topoisomerase VI is a chirally-selective, preferential DNA decatenase (2021) (0)
- Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p] (2015) (0)
- Regulation of poly(gamma-glutamycysteinyl)glycine synthesis (1989) (0)
- Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex (2008) (0)
- Biochemical methods to monitor loading and activation of hexameric helicases. (2022) (0)
- X-ray crystal structure of human cyclic GMP-AMP synthase (cGAS) (2013) (0)
- Mycobacterium tuberculosis gyrase type IIA topoisomerase C-terminal domain (2012) (0)
- S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3 (2011) (0)
- Single-molecule dynamics of DNA gyrase in evolutionarily distant bacteria Mycobacterium tuberculosis and Escherichia coli (2023) (0)
- Corrections (2018) (0)
- N-TERMINAL DOMAIN OF DNA REPLICATION PROTEIN DNAB (1999) (0)
- Single Molecule Analysis of Substeps in the Mechanochemical Cycle of DNA Gyrase (2010) (0)
- IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings (2023) (0)
- Crystal structure of the histone deposition protein Asf1 (2003) (0)
- Mixing it up for Protein Crystallization (2005) (0)
- Decision letter: The complete structure of the human TFIIH core complex (2019) (0)
- Structure of the Bacterial Transcription Termination Factor Rho in Complex with the Regulatory Factor NusG (2016) (0)
- N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 (2000) (0)
- Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M complex (2008) (0)
- Looking Past the Pictures: Evaluating X-Ray Crystal Structure Papers (2008) (0)
- Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF07_0029) bound to ADP (2010) (0)
- Bending, Twisting, Popping: Protein and Nucleic-Acid Remodeling by ATP-Dependent Machines and Switches (2015) (0)
- The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese (2012) (0)
- Crystal structure of a topoisomerase II complex (2016) (0)
- Topoisomerase II-DNA cleavage complex, apo (2010) (0)
- Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus) (2007) (0)
- Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p] (2015) (0)
- Mycobacterium smegmatis Stf0 Sulfotransferase with Trehalose (2004) (0)
- Topoisomerase VI-B bound to radicicol (2006) (0)
- New fluoroquinolones/nitric oxide donor hybrids: design, synthesis and antitubercular activity (2019) (0)
- Crystal structure of gyrase bound to its inhibitor YacG (2014) (0)
- Computational Design of High-Resolution Protein Crystals (2018) (0)
- Unliganded structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase (2004) (0)
- IOTA: integration optimization, triage and analysis tool for the processing of XFEL diffraction imagesThis article will form part of a virtual special issue of the journal on free-electron laser software (2016) (0)
- Protein structure terminates doubt about how transcription stops (2023) (0)
- STRUCTURE OF THE DNAG CATALYTIC CORE (2000) (0)
- Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog (2014) (0)
- Human topoisomerase II alpha bound to DNA (2012) (0)
- X-ray crystal structure of Rho transcription termination factor in complex with ssRNA substrate and ANPPNP (2003) (0)
- Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]' (2015) (0)
- Topoisomerase VI-B, ADP AlF4- bound dimer form (2005) (0)
- N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 (2000) (0)
- E. coli DnaBC complex bound to ssDNA (2019) (0)
- Structure of the E. coli ParC C-terminal domain (2005) (0)
- STRUCTURE OF THE RNA-BINDING DOMAIN OF THE RHO TRANSCRIPTION TERMINATOR (1999) (0)
- Bacterial initiation protein in complex with Phage inhibitor protein (2016) (0)
- DNA-Stimulated Liquid-Liquid phase separation by eukaryotic topoisomerase ii modulates catalytic function (2022) (0)
- CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM (2000) (0)
- Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP (2014) (0)
- Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation (2015) (0)
- Structure of DNA gyrase subunit A N-terminal domain (2009) (0)
- Crystal structure of Staphylococcal nuclease variant Delta+PHS K133M at cryogenic temperature (2019) (0)
- Structure of a Rho-NusG KOW domain complex (2018) (0)
- Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II bound to ICRF-187 (dexrazoxane) (2003) (0)
- Structure of the Histone H3-Asf1 Chaperone Interaction (2007) (0)
- CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING (1998) (0)
- Ancient Origin of cGAS-ST ING Reveals Mechanism of Universal 2 0 , 3 0 cGAMP Signaling Graphical Abstract Highlights (2015) (0)
- Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A (2006) (0)
- Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A) (2015) (0)
- Micro‐Crystallization of Proteins (2008) (0)
- Faculty Opinions recommendation of Structural analysis of DNA replication fork reversal by RecG. (2002) (0)
- ATP‐dependent control of auto‐assembly and DNA remodeling by the AAA+ replication initiation factor, DnaA (2006) (0)
- Structure of the Yeats Domain, Yaf9 (2009) (0)
- Replication initiator DnaA bound to AMPPCP and single-stranded DNA (2011) (0)
- Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG (2014) (0)
- Editor's evaluation: An empirical energy landscape reveals mechanism of proteasome in polypeptide translocation (2021) (0)
- Topoisomerase II-DNA cleavage complex, metal-bound (2010) (0)
- Circular Permutant of the Tobacco Mosaic Virus (2010) (0)
- PNAS Plus Significance Statements (2015) (0)
- KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT (2000) (0)
- Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection (2015) (0)
- Caught in the Open: A Domain Insertion of M. tuberculosis Gyrase Suppresses ATPase Dimerization. (2019) (0)
- S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 H337R and IP6 (2011) (0)
- Structure of DNA gyrase A C-terminal domain (2004) (0)
- Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution (2014) (0)
- Formylglycine Generating Enzyme from Streptomyces coelicolor (2008) (0)
- Crystal Structure of NtrC4 DNA-binding domain bound to double-stranded DNA (2012) (0)
- Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB) (2004) (0)
- Building A Replication Fork: Structural Synergy And Molecular Crosstalk Between Bacterial Initiators And Helicase Loaders (2009) (0)
- Structure of AMPPCP-bound DnaA from Aquifex aeolicus (2006) (0)
- Topoisomerase II-DNA-AMPPNP complex (2012) (0)
- LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING (1997) (0)
- S. cerevisiae Dbp5 L327V bound to Gle1 H337R and IP6 (2011) (0)
- Structure of the C-terminal domain of the DEAD-box protein Dbp5 (2009) (0)
- Topoisomerase IIA bound to G-segment DNA (2007) (0)
- Development of a Flexible Platform for Studying the Single Molecule Dynamics of Nucleic Acid Manipulating Enzymes by TIRF Microscopy (2014) (0)
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