James Sodetz
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American biologist
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James Sodetzbiology Degrees
Biology
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#19615
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Genetics
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#1957
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Molecular Biology
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#2745
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Biology
James Sodetz's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is James Sodetz Influential?
(Suggest an Edit or Addition)According to Wikipedia, James M. Sodetz is an American biologist, focusing in biochemistry; protein chemistry, protein engineering, and molecular biology; structure-function studies of proteins and enzymes of blood with emphasis on the human complement system, currently the Carolina Distinguished Professor / Biochemistry and Molecular Biology at University of South Carolina and an Elected Fellow of the American Association for the Advancement of Science.
James Sodetz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein. (1977) (183)
- Carbohydrate composition and identification of blood group A, B, and H oligosaccharide structures on human Factor VIII/von Willebrand factor. (1979) (115)
- The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure. (1980) (111)
- Structure of Human C8 Protein Provides Mechanistic Insight into Membrane Pore Formation by Complement* (2011) (96)
- Complementary DNA and derived amino acid sequence of the alpha subunit of human complement protein C8: evidence for the existence of a separate alpha subunit messenger RNA. (1987) (93)
- Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9. (1987) (87)
- Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit. (2008) (74)
- The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes. (1987) (71)
- Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. (1978) (66)
- The effect of ϵ-amino caproic acid on the gross conformation of plasminogen and plasmin (1975) (62)
- Evidence of direct insertion of terminal complement proteins into cell membrane bilayers during cytolysis. Labeling by a photosensitive membrane probe reveals a major role for the eighth and ninth components. (1983) (61)
- Multiplicity of rabbit plasminogen. Physical characterization. (1972) (60)
- Identity of the Segment of Human Complement C8 Recognized by Complement Regulatory Protein CD59 (*) (1995) (55)
- Role of the beta subunit in interaction of the eighth component of human complement with the membrane-bound cytolytic complex. (1981) (46)
- Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential. (2002) (44)
- Evidence that C5b recognizes and mediates C8 incorporation into the cytolytic complex of complement. (1987) (42)
- The mechanism of activation of rabbit plasminogen by urokinase. (1975) (40)
- Human complement protein C8γ (2000) (37)
- Proteins of the Membrane Attack Complex (1998) (36)
- Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. (2002) (36)
- Binding of the eighth component of human complement to the soluble cytolytic complex is mediated by its beta subunit. (1980) (36)
- Chromosomal assignment of genes encoding the α, β, and γ subunits of human complement protein C8: Identification of a close physical linkage between the α and the β loci (1989) (36)
- Structure and function of C8 in the membrane attack sequence of complement. (1989) (35)
- Analysis of the specific association of the eighth and ninth components of human complement: identification of a direct role for the alpha subunit of C8. (1985) (33)
- Function of subunits within the eighth component of human complement: selective removal of the gamma chain reveals it has no direct role in cytolysis. (1984) (33)
- Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain. (2007) (30)
- [23] Rabbit plasminogen and plasmin isozymes (1976) (30)
- Amino terminal amino acid sequences and carbohydrate of the two major forms of rabbit plasminogen. (1973) (30)
- Genomic structure of the human complement protein C8 gamma: homology to the lipocalin gene family. (1994) (29)
- Biosynthesis of C8 by hepatocytes. Differential expression and intracellular association of the alpha-gamma- and beta-subunits. (1987) (28)
- Measurement of the ratio of the eighth and ninth components of human complement on complement-lysed membranes. (1984) (26)
- Two distinct abnormalities in patients with C8 alpha-gamma deficiency. Low level of C8 beta chain and presence of dysfunctional C8 alpha-gamma subunit. (1990) (26)
- Functional Studies of the MACPF Domain of Human Complement Protein C8α Reveal Sites for Simultaneous Binding of C8β, C8γ, and C9† (2006) (25)
- Functional domains of the alpha subunit of the eighth component of human complement: identification and characterization of a distinct binding site for the gamma chain. (1985) (25)
- Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit. (2002) (24)
- An indel within the C8 alpha subunit of human complement C8 mediates intracellular binding of C8 gamma and formation of C8 alpha-gamma. (2000) (20)
- Membrane attack complex proteins C5b-6, C7, C8, and C9 of human complement. (1988) (20)
- Studies of the association of the eighth and ninth components of human complement within the membrane-bound cytolytic complex. (1983) (19)
- Characterization of rabbit complement component C8. Functional evidence for the species-selective recognition of C8 alpha by homologous restriction factor (CD59). (1994) (19)
- Crystal structure of complement protein C8γ in complex with a peptide containing the C8γ binding site on C8α: Implications for C8γ ligand binding☆ (2008) (19)
- Chimeric and truncated forms of human complement protein C8 alpha reveal binding sites for C8 beta and C8 gamma within the membrane attack complex/perforin region. (1999) (18)
- Regulation of the membrane attack complex of complement. Evidence that C8 gamma is not the target of homologous restriction factors. (1990) (17)
- Expression and Characterization of Recombinant Subunits of Human Complement Component C8: Further Analysis of the Function of C8α and C8γ (1998) (17)
- Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9. (2006) (16)
- Interaction between the C8α-γ and C8β Subunits of Human Complement C8: Role of the C8β N-Terminal Thrombospondin Type 1 Module and Membrane Attack Complex/Perforin Domain† (2002) (16)
- A comparison of steady- and presteady-state kinetics of bovine and human plasmins. (1972) (15)
- The effect of epsilon-amino caproic acid on the gross conformation of plasminogen and plasmin. (1975) (15)
- The Plasma Lipocalins α1-Acid Glycoprotein, Apolipoprotein D, Apolipoprotein M and Complement Protein C8γ (2013) (13)
- Identification of the α-γ subunit of the eighth component of complement (C8) in a patient with systemic lupus erythematosus and absent C8 activity: Patient and family studies (1982) (13)
- Crystal Structure of the MACPF Domain of Human Complement Protein C 8 α in Complex with the C 8 γ Subunit (2008) (12)
- Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family. (2007) (12)
- Rabbit plasminogen and plasmin isozymes. (1976) (11)
- The mechanism of activation of rabbit plasminogen by urokinase. Lack of a preactivation peptide. (1974) (10)
- Membrane pore formation by human complement: functional importance of the transmembrane β-hairpin (TMH) segments of C8α and C9. (2014) (10)
- Human complement protein C8 gamma. (2000) (9)
- Complement Protein C8 (2005) (8)
- A BamHI RFLP of the C8A gene. (1991) (7)
- In vitro expression of the beta subunit of human complement component C8. (1996) (6)
- Complement: Terminal Pathway (2001) (6)
- Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding. (2008) (5)
- Expression and characterization of recombinant subunits of human complement component C8: further analysis of the function of C8 alpha and C8 gamma. (1998) (5)
- Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain. (2002) (5)
- Chromosomal assignment of genes encoding the alpha, beta, and gamma subunits of human complement protein C8: identification of a close physical linkage between the alpha and the beta loci. (1989) (5)
- Genomic organization of human complement protein C8α and further examination of its linkage to C8β (1995) (4)
- Regional chromosomal assignment of genes encoding the α and β subunits of human complement protein C8 to 1p32 (1992) (3)
- Purification of functional subunits of the eighth component of human complement (C8) under nondenaturing conditions. (1984) (3)
- AFFINITY CHROMATOGRAPHY RESOLUTION OF PLASMINOGEN ISOZYMES (1975) (3)
- Genetic deficiency of complement component C8 in the rabbit: Evidence of a translational defect in expression of the α-γ subunit (1991) (3)
- Identification of human Cohn fraction III as a useful source for the simultaneous purification of FIX and FX zymogens. (1980) (3)
- Physical linkage and orientation of the human complement C8α and C8β genes on chromosome 1p32 (1996) (3)
- Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution (2002) (3)
- The eighth component of human complement: molecular basis of C8A (C81) polymorphism (1995) (3)
- A kinetic characterization of the rabbit plasmin isozymes. (1976) (3)
- A BamH1 RFLP of the C8B gene. (1989) (3)
- Identification of the alpha-gamma subunit of the eighth component of complement (C8) in a patient with systemic lupus erythematosus and absent C8 activity: patients and family studies. (1982) (2)
- Physical linkage and orientation of the human complement C8 alpha and C8 beta genes on chromosome 1p32. (1996) (2)
- Binding of the lipocalin C8γ to human complement protein C8α is mediated by loops located at the entrance to the C8γ ligand binding site (2006) (2)
- DNA polymorphism of the human complementC8β gene: formal genetics and intragenic localization (2006) (1)
- Evidence that a single tyrosine in human complement c 8 is essential for binding to complement c 5b 7 (1985) (1)
- Functional Properties and in Vivo Survival of Normal and Asialo Human Factor VIII/VON Willebrand Protein (1977) (1)
- Genomic organization of human complement protein C8 alpha and further examination of its linkage to C8 beta. (1995) (1)
- The role of paramyosin from blood fluke Schistosoma mansoni in inhibition of the complement system (2008) (1)
- Regional chromosomal assignment of genes encoding the alpha and beta subunits of human complement protein C8 to 1p32. (1992) (1)
- Characterization of truncated and chimeric forms of recombinant human C8 reveal the location of binding sites in the C8α subunit (1998) (0)
- Binding of the lipocalin C8gamma to human complement protein C8alpha is mediated by loops located at the entrance to the C8gamma ligand binding site. (2006) (0)
- Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins (2008) (0)
- Expression and Characterization of Recombinant Subunits of Human Complement Component C 8 : Further Analysis of the Function of C 8 a and C 8 g 1 (1998) (0)
- Structure of human C8 suggests how complement forms circular membrane pores (2011) (0)
- Studies of the interaction of C8 and C9 within the membrane-bound cytolytic complex of complement (1982) (0)
- Oligosaccharide Structures on Human Factor VIII / Van Willebrand Factor * (2002) (0)
- Genetic deficiency of complement component C8 in the rabbit: evidence of a translational defect in expression of the alpha-gamma subunit. (1991) (0)
- Human Complement Protein C 8 : The " Hole " Story (2013) (0)
- Crystal Structure of Human Complement Component C8 (2011) (0)
- The activation and inhibition of fibrinolysis. (1975) (0)
- DNA polymorphism of the human complement C8 beta gene: formal genetics and intragenic localization. (1989) (0)
- Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8 (2007) (0)
- Chromosomal assignment and physical linkage of the human C8 loci: implications regarding C8 polymorphisms and deficiencies. (1990) (0)
- X-ray structure of Human Complement Protein C8gamma at pH=7.O (2002) (0)
- Crystal Structure of Recombinant Human Complement Protein C8gamma (2007) (0)
- X-ray structure of Human Complement Protein C8gamma Y83W Mutant (2007) (0)
- Crystal Structure of Human Complement Protein C8gamma with Laurate (2007) (0)
- Genomic organization of the. alpha. subunit of human complement C8 (1991) (0)
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