James Kadonaga
#118,870
Most Influential Person Now
American biologist
James Kadonaga's AcademicInfluence.com Rankings
James Kadonagabiology Degrees
Biology
#7932
World Rank
#10930
Historical Rank
Molecular Biology
#958
World Rank
#981
Historical Rank

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Biology
James Kadonaga's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is James Kadonaga Influential?
(Suggest an Edit or Addition)According to Wikipedia, James T. Kadonaga is an American biologist, currently the Amylin Endowed Chair in Lifesciences at University of California, San Diego. Education Kadonga has a bachelor's degree in chemistry from MIT, where he received the Alpha Chi Sigma Prize and the American Institute of Chemists Certificate. His graduate studies was at Harvard University under Jeremy R. Knowles. He was a DuPont Fellow.
James Kadonaga's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain (1987) (1330)
- The RNA polymerase II core promoter. (2003) (1178)
- Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. (1986) (1027)
- Affinity purification of sequence-specific DNA binding proteins. (1986) (896)
- Tools for neuroanatomy and neurogenetics in Drosophila (2008) (874)
- What's Up and Down with Histone Deacetylation and Transcription? (1997) (873)
- Promoter-specific activation of RNA polymerase II transcription by Sp1 (1986) (836)
- Going the distance: a current view of enhancer action. (1998) (795)
- A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication (1987) (734)
- ACF, an ISWI-Containing and ATP-Utilizing Chromatin Assembly and Remodeling Factor (1997) (653)
- The RNA polymerase II core promoter: a key component in the regulation of gene expression. (2002) (651)
- Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. (1986) (638)
- Eukaryotic Transcription: An Interlaced Network of Transcription Factors and Chromatin-Modifying Machines (1998) (557)
- The RCAF complex mediates chromatin assembly during DNA replication and repair (1999) (540)
- The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. (1997) (525)
- Regulation of gene expression via the core promoter and the basal transcriptional machinery. (2010) (478)
- Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters. (1996) (435)
- Regulation of RNA Polymerase II Transcription by Sequence-Specific DNA Binding Factors (2004) (393)
- Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo (2009) (385)
- The RNA polymerase II core promoter - the gateway to transcription. (2008) (385)
- The Downstream Promoter Element DPE Appears To Be as Widely Used as the TATA Box in Drosophila Core Promoters (2000) (384)
- Chromatin remodeling by ATP-dependent molecular machines. (2003) (369)
- Distinct regions of Sp1 modulate DNA binding and transcriptional activation. (1988) (363)
- Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II. (1991) (349)
- ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. (1999) (348)
- p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation. (1998) (344)
- Sequence-specific antirepression of histone H1-mediated inhibition of basal RNA polymerase II transcription. (1991) (326)
- SWI2/SNF2 and Related Proteins: ATP-Driven Motors That Disrupt-Protein–DNA Interactions? (1997) (309)
- Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. (1985) (303)
- Role of chromatin structure in the regulation of transcription by RNA polymerase II. (1993) (284)
- Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs. (2001) (273)
- Drosophila NAP-1 is a core histone chaperone that functions in ATP-facilitated assembly of regularly spaced nucleosomal arrays (1996) (273)
- Distinct activities of CHD1 and ACF in ATP-dependent chromatin assembly (2005) (273)
- CHD1 Motor Protein Is Required for Deposition of Histone Variant H3.3 into Chromatin in Vivo (2007) (268)
- The “Dark Side” of Chromatin Remodeling Repressive Effects on Transcription (1999) (251)
- Strategies for Protein Purification and Characterization A Laboratory Course Manual (1996) (242)
- Perspectives on the RNA polymerase II core promoter (2012) (240)
- Biochemical Analysis of Distinct Activation Functions in p300 That Enhance Transcription Initiation with Chromatin Templates (1999) (238)
- The MTE, a new core promoter element for transcription by RNA polymerase II. (2004) (221)
- Interaction between the DrosophilaCAF-1 and ASF1 Chromatin Assembly Factors (2001) (217)
- NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro. (1996) (207)
- Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. (1998) (205)
- Rational design of a super core promoter that enhances gene expression (2006) (190)
- Acf1 confers unique activities to ACF/CHRAC and promotes the formation rather than disruption of chromatin in vivo. (2004) (187)
- Potentiation of RNA polymerase II transcription by Gal4-VP16 during but not after DNA replication and chromatin assembly. (1993) (184)
- A basal transcription factor that activates or represses transcription. (2000) (180)
- Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. (1995) (176)
- ATP-dependent nucleosome reconfiguration and transcriptional activation from preassembled chromatin templates. (1994) (170)
- HARP Is an ATP-Driven Annealing Helicase (2008) (164)
- Strand pairing by Rad54 and Rad51 is enhanced by chromatin. (2002) (153)
- The Many Faces of Chromatin Remodeling SWItching beyond Transcription (2001) (144)
- The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein (1996) (141)
- The DPE, a core promoter element for transcription by RNA polymerase II (2002) (137)
- Identification of a minimal set of proteins that is sufficient for accurate initiation of transcription by RNA polymerase II. (1993) (132)
- The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. (2009) (123)
- Chromatin assembly by DNA-translocating motors (2003) (120)
- Human promoters are intrinsically directional. (2015) (117)
- Nucleosome mobility and the maintenance of nucleosome positioning. (1997) (117)
- Binding of the Sp1 transcription factor by the human Harvey ras1 proto-oncogene promoter. (1986) (114)
- Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State (2013) (112)
- Assembly and disassembly of the Drosophila RNA polymerase II complex during transcription. (1990) (108)
- The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. (2010) (108)
- Chromatin assembly in vitro with purified recombinant ACF and NAP-1. (2003) (107)
- Strategies for the reconstitution of chromatin (2004) (105)
- Purification of sequence-specific binding proteins by DNA affinity chromatography. (1991) (102)
- Caudal, a key developmental regulator, is a DPE-specific transcriptional factor. (2008) (100)
- In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins (1993) (100)
- p300 Forms a Stable, Template-Committed Complex with Chromatin: Role for the Bromodomain (2001) (99)
- Sequence-specific transcriptional antirepression of the Drosophila Krüppel gene by the GAGA factor. (1991) (95)
- Dynamics of ATP-dependent chromatin assembly by ACF (2002) (94)
- ATP-facilitated Chromatin Assembly with a Nucleoplasmin-like Protein from Drosophila melanogaster* (1996) (93)
- The punctilious RNA polymerase II core promoter (2017) (93)
- Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1 (1996) (91)
- The role of the beta-lactamase signal sequence in the secretion of proteins by Escherichia coli. (1984) (89)
- HMG17 is a chromatin-specific transcriptional coactivator that increases the efficiency of transcription initiation. (1995) (83)
- Threshold phenomena and long-distance activation of transcription by RNA polymerase II. (1992) (78)
- Chromatin assembly factors: a dual function in nucleosome formation and mobilization? (1997) (78)
- Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos. (1991) (77)
- TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription. (2008) (77)
- Identification of a rapidly formed nonnucleosomal histone-DNA intermediate that is converted into chromatin by ACF. (2011) (75)
- Fractionation of the general RNA polymerase II transcription factors from Drosophila embryos. (1990) (74)
- Mechanism of transcriptional antirepression by GAL4-VP16. (1992) (74)
- Assembly of regularly spaced nucleosome arrays by Drosophila chromatin assembly factor 1 and a 56-kDa histone-binding protein. (1995) (72)
- The DPE, a conserved downstream core promoter element that is functionally analogous to the TATA box. (1998) (72)
- TRF2, but not TBP, mediates the transcription of ribosomal protein genes (2014) (71)
- Forced unraveling of nucleosomes assembled on heterogeneous DNA using core histones, NAP-1, and ACF. (2005) (71)
- Biochemical Analysis of Chromatin Containing RecombinantDrosophila Core Histones* (2002) (67)
- Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation. (2005) (67)
- Binding of Acf1 to DNA Involves a WAC Motif and Is Important for ACF-Mediated Chromatin Assembly (2002) (67)
- MPE-seq, a new method for the genome-wide analysis of chromatin structure (2015) (66)
- Perspectives on the RNA polymerase II core promoter. (2006) (62)
- Three Key Subregions Contribute to the Function of the Downstream RNA Polymerase II Core Promoter (2010) (56)
- The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters (2017) (56)
- Dehydroquinate synthase from Escherichia coli: purification, cloning, and construction of overproducers of the enzyme. (1984) (56)
- The prenucleosome, a stable conformational isomer of the nucleosome (2015) (55)
- HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility. (2009) (55)
- AFFINITY PURIFICATION OF SEQUENCESPECIFIC DNA BINDING PROTEINS (1986) (55)
- Annealing helicase 2 (AH2), a DNA-rewinding motor with an HNH motif (2010) (54)
- Exploring the transcription-chromatin interface. (2000) (52)
- Evidence against a genomic code for nucleosome positioning Reply to “Nucleosome sequence preferences influence in vivo nucleosome organization” (2010) (49)
- A simple and efficient method for chemical mutagenesis of DNA. (1985) (48)
- The soluble nuclear fraction, a highly efficient transcription extract from Drosophila embryos. (1994) (47)
- Stereoselective synthesis of cyclopentene derivatives from 1,3-dienes (1981) (46)
- ATP-dependent chromatin assembly is functionally distinct from chromatin remodeling (2013) (45)
- Functional analysis of Drosophila transcription factor IIB. (1992) (42)
- A Conserved N-terminal Motif in Rad54 Is Important for Chromatin Remodeling and Homologous Strand Pairing* (2004) (42)
- The RNA Polymerase II Core Promoter in Drosophila (2019) (40)
- Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex (2003) (40)
- The tardigrade damage suppressor protein binds to nucleosomes and protects DNA from hydroxyl radicals (2019) (39)
- Promoter Structure and Transcriptional Activation with Chromatin Templates Assembled In Vitro (1998) (39)
- Role of chromatin structure in the regulation of transcription by RNA polymerase II. (1994) (38)
- TRF2 and the evolution of the bilateria (2014) (36)
- NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes (2018) (32)
- Transcriptional Analysis of Chromatin Assembled with Purified ACF and dNAP1 Reveals That Acetyl-CoA Is Required for Preinitiation Complex Assembly* (2000) (30)
- Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300 (2006) (30)
- Simian virus 40 origin- and T-antigen-dependent DNA replication with Drosophila factors in vitro (1994) (29)
- A general method for purification of H1 histones that are active for repression of basal RNA polymerase II transcription. (1991) (28)
- , Action Going the Distance : A Current View of Enhancer (2008) (27)
- Signal sequence mutants of beta-lactamase. (1985) (27)
- Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif (2014) (23)
- Role of mono- and divalent metal cations in the catalysis by yeast aldolase. (1983) (22)
- Perspectives on Unidirectional versus Divergent Transcription. (2015) (20)
- Biochemical Analysis of Transcriptional Repression byDrosophila Histone Deacetylase 1* (2001) (18)
- Identification of the Human DPR Promoter Element by using Machine Learning (2020) (18)
- a method for the analysis (2015) (18)
- Purification of Sequence‐Specific DNA‐Binding Proteins by Affinity Chromatography (1993) (17)
- Enhancement of homology-directed repair with chromatin donor templates in cells (2020) (15)
- A simple and versatile system for the ATP-dependent assembly of chromatin (2017) (14)
- Identification of the human DPR core promoter element using machine learning (2020) (14)
- A spectrum of mechanisms for the assembly of the RNA polymerase II transcription preinitiation complex (1995) (13)
- Biochemical Analysis of Histone Deacetylase-independent Transcriptional Repression by MeCP2* (2013) (13)
- Eukaryotic Transcription : An Interlaced Review Network of Transcription Factors and Chromatin-Modifying Machines (1998) (12)
- Periodic binding of individual core histones to DNA: inadvertent purification of the core histone H2B as a putative enhancer-binding factor. (1992) (11)
- The use of chromatin templates to recreate transcriptional regulatory phenomena in vitro. (1998) (10)
- Prenucleosomes and Active Chromatin. (2015) (9)
- Gene transcription: basal and regulated transcription by RNA polymerase II. (1990) (9)
- Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog (2019) (9)
- The Annealing Helicase and Branch Migration Activities of Drosophila HARP (2014) (9)
- Structure and Function of the Small Subunit of TFIIF (RAP30) from Drosophilamelanogaster(*) (1995) (8)
- Chromosomes and expression mechanisms Chromatin: the packaging is the message (1999) (8)
- Reply to Evidence against a genomic code for nucleosome positioning (2010) (7)
- Branching out with DNA helicases. (2011) (7)
- Identification of evolutionarily conserved downstream core promoter elements required for the transcriptional regulation of Fushi tarazu target genes (2019) (6)
- The transformation of the DNA template in RNA polymerase II transcription: a historical perspective (2019) (6)
- Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster. (1995) (6)
- ATP-Driven Motors That Disrupt Protein – DNA Interactions ? (1997) (6)
- Activation of RNA polymerase II by topologically linked DNA-tracking proteins. (1997) (5)
- Biochemical analysis of the role of chromatin structure in the regulation of transcription by RNA polymerase II. (1993) (4)
- M olecular Basis of Transcription Molecular Basis of Transcription (1)
- DPE-dependent versus TATA-dependent transcription TBP , Mot 1 , and NC 2 establish a regulatory circuit that controls Material Supplemental (2008) (1)
- The Many Faces of Chromatin Minireview Remodeling: SWItching beyond Transcription (2001) (1)
- SWI2/SNF2 and Related Proteins: Minireview ATP-Driven Motors That Disrupt Protein-DNA Interactions? (1997) (1)
- NDF is a transcription factor that stimulates elongation by RNA polymerase II (2022) (1)
- Reconstitution of Chromatin by Stepwise Salt Dialysis. (2021) (1)
- What ’ s Up and Down with Minireview Histone Deacetylation and Transcription ? (1997) (0)
- Purification of Sequence‐Specific DNA‐Binding Proteins by Affinity Chromatography (1993) (0)
- 3D models from "Human TFIID binds to core promoter DNA in a reorganized structural state" (2014) (0)
- Annealing Helicase HARP: A Single Molecule Study (2011) (0)
- ASF1 Chromatin Assembly Factors CAF-1 and Drosophila Interaction between the (2014) (0)
- Letters to the Editor (2023) (0)
- UNIVERSITY OF CALIFORNIA, SAN DIEGO Evolution and Diversification of the Core Transcription Regulatory Network A dissertation submitted in partial satisfaction of the requirements for the degree of Doctor of Philosophy in Biology by (2015) (0)
- UC San Diego UC San Diego Previously Published Works Title Prenucleosomes and Active Chromatin (2016) (0)
- The transformation of the DNA template in RNA polymerase II transcription: a historical perspective (2019) (0)
- [Chromatin assembly and reconfiguration]. (1998) (0)
- transcriptional factor Caudal , a key developmental regulator , is a DPE-specific Material Supplemental (2008) (0)
- Correction for Ishii et al., MPE-seq, a new method for the genome-wide analysis of chromatin structure (2019) (0)
- Course 3 Regulation of transcription by RNA polymerase II (2005) (0)
- Mechanical unraveling of nucleosomes assembled on heterogeneous DNA using core histones, NAP-1, and ACF (2005) (0)
- Functional analysis : rosophila transcription factor (1992) (0)
- Analysis of theDrosophilaand human DPR elements reveals a distinct human variant whose specificity can be enhanced by machine learning (2023) (0)
- The “ Dark Side ” of Chromatin Minireview Remodeling : Repressive Effects on Transcription (1999) (0)
- Eukaryotic Transcriptional Specificity Conferred by DNA-Binding Proteins (1987) (0)
- UC San Diego UC San Diego Previously Published Works Title Perspectives on Unidirectional versus Divergent Transcription (0)
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