James W. Fawcett

Q: What Schools Are Affiliated With James W. Fawcett

James W. Fawcett is affiliated with the following schools: Charles University, University of Toronto, University of Cambridge

James W. Fawcett's AcademicInfluence.com Rankings

James W. Fawcett

Biology

#5934

World Rank

#8539

Historical Rank

Neuroscience

#694

World Rank

#726

Historical Rank

biology Degrees

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Biology

James W. Fawcett's Degrees

Doctorate Medicine Stanford University

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James W. Fawcett's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Chondroitinase ABC promotes functional recovery after spinal cord injury (2002) (1822)
The glial scar and central nervous system repair (1999) (1807)
Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex (2002) (1487)
Regressive events in neurogenesis. (1984) (1314)
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials (2007) (765)
The oligodendrocyte precursor cell in health and disease (2001) (667)
Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC (2001) (572)
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system (2007) (540)
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures (2007) (493)
Neurocan Is Upregulated in Injured Brain and in Cytokine-Treated Astrocytes (2000) (465)
Chondroitin sulphate proteoglycans in the CNS injury response. (2002) (457)
Animals lacking link protein have attenuated perineuronal nets and persistent plasticity. (2010) (440)
The migration of neural crest cells and the growth of motor axons through the rostral half of the chick somite. (1985) (430)
Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation (2009) (430)
Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration (2005) (393)
Assembly of a new growth cone after axotomy: the precursor to axon regeneration (2012) (370)
Extracellular matrix and perineuronal nets in CNS repair (2011) (364)
Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? (2007) (358)
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design (2007) (330)
Formation of topographic maps. (1988) (323)
The perineuronal net and the control of CNS plasticity (2012) (320)
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. (2011) (316)
Composition of Perineuronal Net Extracellular Matrix in Rat Brain (2006) (313)
Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS? (2004) (306)
The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system. (2014) (297)
Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components (2006) (294)
Overcoming inhibition in the damaged spinal cord. (2006) (284)
Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs (2010) (280)
Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity (2016) (280)
Comparing Astrocytic Cell Lines that Are Inhibitory or Permissive for Axon Growth: the Major Axon-Inhibitory Proteoglycan Is NG2 (1999) (278)
Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death (1986) (249)
Versican Is Upregulated in CNS Injury and Is a Product of Oligodendrocyte Lineage Cells (2002) (246)
The soft mechanical signature of glial scars in the central nervous system (2017) (241)
Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces (2010) (229)
The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function (2019) (219)
Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy. (2010) (218)
Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures (1999) (209)
Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes. (2002) (209)
Targeting the neural extracellular matrix in neurological disorders (2013) (208)
The Time Course of Loss of Dopaminergic Neurons and the Gliotic Reaction Surrounding Grafts of Embryonic Mesencephalon to the Striatum (1996) (206)
Peripheral nerve regeneration. (1990) (205)
An inhibitor of neurite outgrowth produced by astrocytes. (1994) (205)
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics (2007) (201)
Building a Bridge: Engineering Spinal Cord Repair (2002) (201)
Intrinsic neuronal determinants of regeneration (1992) (189)
Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin‐R in the rat spinal cord (2008) (188)
Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex (2013) (186)
Chondroitinase Combined with Rehabilitation Promotes Recovery of Forelimb Function in Rats with Chronic Spinal Cord Injury (2011) (184)
Chondroitin sulphate proteoglycans: inhibitory components of the glial scar. (2001) (182)
The growth of axons in three-dimensional astrocyte cultures. (1989) (173)
Chondroitin 6‐sulphate synthesis is up‐regulated in injured CNS, induced by injury‐related cytokines and enhanced in axon‐growth inhibitory glia (2005) (173)
Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC. (2008) (165)
Promoting plasticity in the spinal cord with chondroitinase improves functional recovery after peripheral nerve repair. (2007) (162)
Chondroitin sulfate proteoglycans in neural development and regeneration (2005) (160)
Muscle basal lamina: a new graft material for peripheral nerve repair. (1986) (159)
The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain (2004) (157)
Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum (2007) (153)
Activity and the control of ganglion cell death in the rat retina. (1984) (152)
The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK (2005) (150)
An efficient method for derivation and propagation of glioblastoma cell lines that conserves the molecular profile of their original tumours (2009) (149)
Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors. (1995) (148)
Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury (2011) (148)
Chondroitin sulfate proteoglycans in neural development and regeneration (2005) (146)
In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity (2010) (146)
How does chondroitinase promote functional recovery in the damaged CNS? (2007) (144)
Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling (2011) (144)
α9 Integrin Promotes Neurite Outgrowth on Tenascin-C and Enhances Sensory Axon Regeneration (2009) (144)
Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons—II. Effects on nigral transplantsin vivo (1993) (141)
GDNF enhances dopaminergic cell survival and fibre outgrowth in embryonic nigral grafts. (1996) (137)
Oligodendrocytes repel axons and cause axonal growth cone collapse. (1989) (128)
The role of local protein synthesis and degradation in axon regeneration (2010) (127)
The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines (2006) (124)
Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retinas of dystrophic Royal College of Surgeons rats. (2004) (123)
Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains* (2013) (123)
The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways (2003) (122)
Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression (2014) (122)
The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease. (2015) (121)
Mechanosensitivity of astrocytes on optimized polyacrylamide gels analyzed by quantitative morphometry (2010) (120)
Chondroitin sulfate: a key molecule in the brain matrix. (2012) (119)
The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain (2013) (119)
Rab11 and Its Effector Rab Coupling Protein Contribute to the Trafficking of β1 Integrins during Axon Growth in Adult Dorsal Root Ganglion Neurons and PC12 Cells (2010) (119)
Chondroitin Sulfate Proteoglycans and Microglia Prevent Migration and Integration of Grafted Müller Stem Cells into Degenerating Retina (2008) (118)
Perisynaptic Chondroitin Sulfate Proteoglycans Restrict Structural Plasticity in an Integrin-Dependent Manner (2012) (117)
Chondroitin sulphate proteoglycans in the central nervous system: changes and synthesis after injury. (2003) (115)
Inhibiting Glycosaminoglycan Chain Polymerization Decreases the Inhibitory Activity of Astrocyte-Derived Chondroitin Sulfate Proteoglycans (2007) (114)
Assessment of the biocompatibility of photosensitive polyimide for implantable medical device use. (2009) (113)
Defeating inhibition of regeneration by scar and myelin components. (2012) (112)
The role of Schwann cells in the regeneration of peripheral nerve axons through muscle basal lamina grafts (1991) (111)
Reduction in CNS scar formation without concomitant increase in axon regeneration following treatment of adult rat brain with a combination of antibodies to TGFβ1 and β2 (2001) (111)
N-Cadherin Inhibits Schwann Cell Migration on Astrocytes (1999) (111)
Molecular control of brain plasticity and repair. (2009) (107)
Therapeutic time window for the application of chondroitinase ABC after spinal cord injury (2008) (107)
Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons—i. Effectsin vitro (1993) (105)
Repair of spinal cord injuries: where are we, where are we going? (2002) (105)
6-Sulphated Chondroitins Have a Positive Influence on Axonal Regeneration (2011) (104)
A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat (2013) (104)
Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology (2015) (104)
Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system (1997) (102)
Relationship between sprouting axons, proteoglycans and glial cells following unilateral nigrostriatal axotomy in the adult rat (2002) (102)
The role of electrical activity in the formation of topographic maps in the nervous system (1985) (101)
Schwann cell migration is integrin‐dependent and inhibited by astrocyte‐produced aggrecan (2010) (99)
Chondroitinase ABC has a long‐lasting effect on chondroitin sulphate glycosaminoglycan content in the injured rat brain (2007) (99)
A Glial Cell Line-Derived Neurotrophic Factor-Secreting Clone of the Schwann Cell Line SCTM41 Enhances Survival and Fiber Outgrowth from Embryonic Nigral Neurons Grafted to the Striatum and to the Lesioned Substantia Nigra (1999) (99)
Increased survival of rat EGF-generated CNS precursor cells using B27 supplemented medium (2004) (98)
Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons (2009) (98)
A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo (2007) (97)
Chondroitinase ABC Combined with Neurotrophin NT-3 Secretion and NR2D Expression Promotes Axonal Plasticity and Functional Recovery in Rats with Lateral Hemisection of the Spinal Cord (2011) (96)
“GAG-ing with the neuron”: The role of glycosaminoglycan patterning in the central nervous system (2015) (93)
Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons (2011) (92)
Combination treatment with chondroitinase ABC in spinal cord injury—breaking the barrier (2013) (91)
Axonal mRNAs: Characterisation and role in the growth and regeneration of dorsal root ganglion axons and growth cones (2009) (90)
Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury (2011) (90)
Combination treatment with anti‐Nogo‐A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury (2013) (90)
Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity (2018) (89)
Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS (2003) (88)
Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory (2017) (85)
Interactions between meningeal cells and astrocytes in vivo and in vitro. (1991) (85)
Regulation of RPTPβ/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia (2003) (83)
Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord. (2010) (83)
Spinal cord repair: from experimental models to human application (1998) (82)
Schwann Cells Transplanted into Normal and X-Irradiated Adult White Matter Do Not Migrate Extensively and Show Poor Long-Term Survival (2000) (82)
The astrocyte/meningeal cell interface – a barrier to successful nerve regeneration? (2001) (81)
The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective (1999) (80)
Migration of oligodendrocyte precursors on astrocytes and meningeal cells. (1995) (79)
ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons (2012) (79)
Astrocytes and oligodendrocytes can be generated from NG2+ progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice (2009) (78)
Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon (2004) (77)
AXONAL REGENERATION (1996) (76)
Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord (2016) (75)
Inosine promotes recovery of skilled motor function in a model of focal brain injury. (2006) (74)
An analysis of astrocytic cell lines with different abilities to promote axon growth (1995) (73)
Astrocyte-Produced Ephrins Inhibit Schwann Cell Migration via VAV2 Signaling (2010) (73)
Microchannels as Axonal Amplifiers (2008) (73)
Large animal and primate models of spinal cord injury for the testing of novel therapies (2015) (73)
Characterization of tests of functional recovery after median and ulnar nerve injury and repair in the rat forelimb (2007) (72)
Role of Chondroitin Sulfate Proteoglycans in Axonal Conduction in Mammalian Spinal Cord (2010) (72)
A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo (2012) (71)
Long Micro-Channel Electrode Arrays: A Novel Type of Regenerative Peripheral Nerve Interface (2009) (71)
Integrins promote axonal regeneration after injury of the nervous system (2018) (70)
Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts (2018) (70)
NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature. (2011) (69)
Chondroitinase Improves Anatomical and Functional Outcomes After Primate Spinal Cord Injury (2019) (69)
N-Cadherin Influences Migration of Oligodendrocytes on Astrocyte Monolayers (2000) (69)
Two separate metalloproteinase activities are responsible for the shedding and processing of the NG2 proteoglycan in vitro (2005) (67)
Robust Regeneration of CNS Axons through a Track Depleted of CNS Glia (2000) (67)
The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity (2016) (66)
Expression and glycanation of the NG2 proteoglycan in developing, adult, and damaged peripheral nerve (2003) (66)
Cytokine‐induced changes in the ability of astrocytes to support migration of oligodendrocyte precursors and axon growth (1998) (66)
Polyimide micro-channel arrays for peripheral nerve regenerative implants (2008) (65)
Combinatorial ShcA Docking Interactions Support Diversity in Tissue Morphogenesis (2007) (65)
Limited growth of severed CNS axons after treatment of adult rat brain with hyaluronidase (2003) (64)
The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult? (2019) (64)
Challenges for defining minimal clinically important difference (MCID) after spinal cord injury (2014) (64)
The Kinesin-2 Family Member KIF3C Regulates Microtubule Dynamics and Is Required for Axon Growth and Regeneration (2013) (63)
Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors. (1993) (63)
The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease (1996) (63)
An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss (2008) (62)
Recommended guidelines for studies of human subjects with spinal cord injury (2005) (62)
Training and anti-CSPG combination therapy for spinal cord injury (2012) (61)
Dopamine cells in nigral grafts differentiate prior to implantation (1999) (61)
A comparative study of preparation techniques for improving the viability of striatal grafts using vital stains, in vitro cultures, and in vivo grafts. (1996) (60)
Heparan sulphate proteoglycans in glia and in the normal and injured CNS: expression of sulphotransferases and changes in sulphation (2008) (60)
N-Cadherin Is Involved in Axon-Oligodendrocyte Contact and Myelination (2001) (59)
Report of International Clinical Trials Workshop on Spinal Cord Injury February 20–21, 2004, Vancouver, Canada (2004) (58)
Concurrent recordings of bladder afferents from multiple nerves using a microfabricated PDMS microchannel electrode array. (2012) (58)
Axon behaviour at Schwann cell – astrocyte boundaries: manipulation of axon signalling pathways and the neural adhesion molecule L1 can enable axons to cross (2004) (56)
Brain Damage, Brain Repair (2002) (56)
Regeneration in the CNS: optimism mounts (1998) (56)
Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells (2010) (56)
Extrinsic and intrinsic factors controlling axonal regeneration after spinal cord injury (2009) (55)
Integrin signalling and traffic during axon growth and regeneration (2014) (55)
Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait (2015) (54)
Neurochemical biomarkers in spinal cord injury (2019) (53)
Kindlin-1 Enhances Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans and Promotes Sensory Axon Regeneration (2012) (52)
Delivery of a lentiviral vector in a Pluronic F127 gel to cells of the central nervous system. (2005) (52)
Effects of Digesting Chondroitin Sulfate Proteoglycans on Plasticity in Cat Primary Visual Cortex (2013) (52)
Proteoglycans Provide Neurite Guidance at an Astrocyte Boundary (1997) (51)
Compound eyes project stripes on the optic tectum in Xenopus (1982) (51)
Assessment of Thermal Pain Sensation in Rats and Mice Using the Hargreaves Test. (2017) (50)
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury* (2016) (50)
Selective rab11 transport and the intrinsic regenerative ability of CNS axons (2017) (50)
Enhanced Axonal Regeneration Following Combined Demyelination plus Schwann Cell Transplantation Therapy in the Injured Adult Spinal Cord (1999) (49)
Neu3 Sialidase-Mediated Ganglioside Conversion Is Necessary for Axon Regeneration and Is Blocked in CNS Axons (2014) (48)
The retinotectal fibre pathways from normal and compound eyes in Xenopus. (1982) (48)
Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters (2020) (47)
The glial response to injury and its role in the inhibition of CNS repair. (2006) (47)
Regeneration in the mammalian optic nerve. (2001) (46)
Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS (2015) (46)
Microchannel Electrodes for Recording and Stimulation: In Vitro Evaluation (2009) (46)
Position statement on the sale of unproven cellular therapies for spinal cord injury The International Campaign for Cures of Spinal Cord Injury Paralysis (2009) (46)
Developmental Regulation of αv Integrins Produces Functional Changes in Astrocyte Behavior (2001) (45)
Altered CNS response to injury in the MRL/MpJ mouse (2004) (45)
Role of extracellular factors in axon regeneration in the CNS: implications for therapy. (2008) (45)
Intrinsic Determinants of Axon Regeneration (2018) (44)
Influence of Extracellular Matrix Components on the Expression of Integrins and Regeneration of Adult Retinal Ganglion Cells (2015) (44)
The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mRNA expression in primary hippocampal and astrocyte cultures. (2004) (43)
Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration (2017) (43)
Regulation of fibronectin alternative splicing during peripheral nerve repair (1999) (43)
A quantitative study of cell death in the substantia nigra following a mechanical lesion of the medial forebrain bundle (1995) (42)
Astrocytes promote neurogenesis from oligodendrocyte precursor cells (2006) (41)
Expression of Schwann cell markers by mammalian neural crest cells in vitro. (1989) (41)
How axons grow down the Xenopus optic nerve. (1981) (41)
The challenges of long-distance axon regeneration in the injured CNS. (2012) (41)
The effect of intraocular tetrodotoxin on the postnatal reduction in the numbers of optic nerve axons in the rat. (1986) (40)
Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteinS (1994) (40)
The effects of protease inhibitors on axon growth through astrocytes. (1990) (39)
Proteoglycans and brain repair. (2004) (38)
Bio-inspired nano tools for neuroscience (2016) (38)
Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--I. Effects in vitro. (1993) (35)
Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent (2016) (35)
High sensitivity recording of afferent nerve activity using ultra-compliant microchannel electrodes: an acute in vivo validation (2012) (35)
Bridge grafts of fibroblast growth factor-4-secreting schwannoma cells promote functioal axonal regeneration in the nigrostriatal pathway of the adult rat (1996) (34)
Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling (2018) (33)
Spinal Cord Repair: Bridging the Divide (2008) (33)
Pathways of Xenopus optic fibres regenerating from normal and compound eyes under various conditions. (1983) (33)
Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--II. Effects on nigral transplants in vivo. (1993) (32)
Activated retinal glia mediated axon regeneration in experimental glaucoma (2012) (32)
Recovery from spinal cord injury: regeneration, plasticity and rehabilitation. (2009) (32)
Analysis of combinatorial variability reveals selective accumulation of the fibronectin type III domains B and D of tenascin-C in injured brain (2010) (32)
Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy (2016) (32)
The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury (2019) (32)
Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration. (2010) (29)
Mechanical matching of implant to host minimises foreign body reaction (2019) (29)
Damage control in the nervous system: rehabilitation in a plastic environment (2009) (29)
Fibre order in the normal Xenopus optic tract, near the chiasma. (1984) (29)
EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment (2017) (28)
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS (2020) (28)
Growth-cone collapse: too much of a good thing? (1993) (28)
Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage (2005) (27)
Neural ECM in regeneration and rehabilitation. (2014) (26)
Astrocytes in culture express fibrillar collagen (2003) (26)
Improving RPE adhesion to Bruch's membrane (2009) (26)
Repair in the central nervous system. (2007) (24)
Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery. (1999) (24)
Mesenchymal stromal cells integrate and form longitudinally-aligned layers when delivered to injured spinal cord via a novel fibrin scaffold (2014) (24)
Axonal growth on astrocytes is not inhibited by oligodendrocytes. (1992) (23)
A Comparative Study of Preparation Techniques for Improving the Viability of Nigral Grafts using Vital Stains, in Vitro Cultures, and in Vivo Grafts (1995) (23)
The visuotectal projections made by Xenopus 'pie slice' compound eyes. (1983) (22)
Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction. (2017) (22)
Spinal cord regeneration. (2005) (22)
Intrinsic mechanisms regulating axon regeneration: an integrin perspective. (2012) (22)
Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy (2007) (21)
Increased axon growth through astrocyte cell lines transfected with urokinase (1998) (21)
The organization of regenerating axons in theXenopus optic nerve (1981) (21)
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing (2021) (20)
Astrocytes and axon regeneration in the central nervous system (1994) (20)
Kinesin KIF4A transports integrin β1 in developing axons of cortical neurons (2014) (20)
Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex (2019) (20)
PI 3‐kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS (2019) (20)
Full length talin stimulates integrin activation and axon regeneration (2015) (20)
Microglia-mediated degradation of perineuronal nets promotes pain (2022) (19)
Differential regenerative ability of sensory and motor neurons (2017) (18)
Use of an implanted sacral nerve stimulator to restore urine voiding in chronically paraplegic dogs. (2013) (18)
A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases (2015) (17)
Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury (2012) (17)
Interaction of glia with a compliant, microstructured silicone surface. (2013) (15)
An integrin approach to axon regeneration (2017) (15)
A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts. (1995) (14)
Regional Regulation of Purkinje Cell Dendritic Spines by Integrins and Eph/Ephrins (2016) (14)
Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation (2019) (14)
NMDA receptor blockade alters the topography of naturally occurring ganglion cell death in the rat retina. (1993) (14)
Optimization of the decision-making process for the selection of therapeutics to undergo clinical testing for spinal cord injury in the North American Clinical Trials Network. (2012) (13)
Perineuronal Nets: A Special Structure in the Central Nervous System Extracellular Matrix (2015) (13)
The Paper that Restarted Modern Central Nervous System Axon Regeneration Research (2018) (13)
The effects of embryonic retinal neurons on neural crest cell differentiation into Schwann cells. (1990) (13)
Factors guiding regenerating retinotectal fibres in the frog Xenopus laevis. (1985) (13)
Targeting inhibitory chondroitin sulphate proteoglycans to promote plasticity after injury. (2014) (13)
On the formation of eye dominance stripes and patches in the doubly-innervated optic tectum of the chick. (1985) (12)
Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons (2012) (12)
Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury (2021) (12)
Recording with microchannel electrodes in a noisy environment (2008) (11)
AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations (2014) (11)
Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting (2020) (11)
Bridging spinal cord injuries (2008) (11)
Canine olfactory ensheathing cells from the olfactory mucosa can be engineered to produce active chondroitinase ABC (2016) (10)
Novel strategies for protection and repair of the central nervous system. (2006) (10)
Neuronal Maturation: Challenges and Opportunities in a Nascent Field (2020) (10)
Neurotrophic factors and neural grafts: a growing field (1993) (10)
Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries (2020) (10)
The Release of Excitatory Amino Acids, Dopamine, and Potassium following Transplantation of Embryonic Mesencephalic Dopaminergic Grafts to the Rat Striatum, and Their Effects on Dopaminergic Neuronal Survival In Vitro (2002) (10)
Formation and Regeneration of Nerve Connections (1993) (10)
Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC (2017) (9)
Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model (2013) (9)
Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration. (2017) (9)
Retinal Glia Promote Dorsal Root Ganglion Axon Regeneration (2015) (8)
Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats (2020) (8)
Mechanics in neuronal development (2009) (7)
Analysis of Schwann-astrocyte interactions using in vitro assays. (2011) (7)
PDMS microchannel regenerative peripheral nerve interface (2013) (7)
Astrocyte influences on oligodendrocyte progenitor migration. (2001) (7)
Challenges for de fi ning minimal clinically important difference ( MCID ) after spinal cord injury (2014) (6)
Expression of Akt and MAPK in the Normal and Regenerating Peripheral Nerves and Their Dorsal Root Ganglia (2009) (6)
In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease. (1995) (6)
Starting the scar: a primary role for pericytes? (2011) (6)
Age-related loss of axonal regeneration is reflected by the level of local translation (2021) (5)
Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in mice (2022) (5)
Regulation of CNS Plasticity Through the Extracellular Matrix (2017) (5)
Prevention of the foreign body response to implantable medical devices by inflammasome inhibition (2022) (5)
Spinal cord transplants: a future treatment for spinal injury? (1995) (5)
Experimental Treatments for Spinal Cord Injury: What you Should Know. (2021) (5)
Astrocyte-Schwann-cell coculture systems. (2012) (5)
A Device for the Implantation of Multiple Cellular Deposits into a Large Volume of Brain from a Single Cannula Site (1996) (4)
Death and Survival in CNS Grafting (2000) (4)
Proteoglycan Sulphation in the Function of the Mature Central Nervous System (2022) (4)
Spinal cord repair: future directions (1992) (4)
Factors influencing the regeneration of axons in the central nervous system (1991) (4)
Evaluation of an elastomer based gold microelectrode array for neural recording applications (2011) (3)
A comparison of the initial retinal ganglion cell projection to the contralateral superior colliculus in albino and pigmented rats. (1990) (3)
An in vitro assay to examine oligodendrocyte precursor cell migration on astrocytes. (2012) (3)
A herpesvirus vector can transduce axotomized brain neurons (2003) (3)
Chondroitin Sulfates in Axon Regeneration and Plasticity (2011) (3)
A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro (2004) (3)
New Model of Ventral Spinal Cord Lesion Induced by Balloon Compression in Rats (2020) (3)
The effect of neurotrophin-5 on the growth and survival of nigral grafts in a rat model of Parkinson's disease. (1994) (3)
Immunohistochemical Identification of Rat Adrenal Cortical Tissue in Situ, in Vitro, and in Intracerebral Adrenal Grafts (1993) (3)
Death and survival in the nervous system (2002) (2)
MODIFYING THE EXTRACELLULAR MATRIX AS A TREATMENT TO IMPROVE FUNCTIONAL RECOVERY AFTER SPINAL CORD INJURY (2008) (2)
Motor, sensory, and autonomic function (2002) (2)
Axon regeneration in the CNS (2002) (2)
Addition of Fresh Blood to Intrastriatal Grafts of Embryonic Mesencephalon into the Hemiparkinsonian Rat Does Not Impair the Survival of Grafted Dopaminergic Neurones (1999) (2)
Perineuronal nets affect memory and learning after synapse withdrawal (2021) (2)
Spinal Cord Regeneration and Functional Recovery: Strategies (2009) (2)
Axonal mRNA in Regeneration (2008) (2)
Long-Term Cultures of Spinal Cord Interneurons (2022) (2)
Restoring the pattern of proteoglycan sulphation in perineuronal nets corrects age-related memory loss (2020) (2)
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury (2022) (2)
Role of chondroitin sulfate proteoglycans (CSPGs) in synaptic plasticity and neurotransmission in mammalian spinal cord. (2009) (2)
Transplantation of Schwann Cell Line Clones Secreting GDNF or BDNF into the Retina of the Royal College of Surgeons Rat Prolongs Visual Function (2003) (2)
Wet Age Related Macular Degeneration (2012) (1)
Interactions between trophoblast, choriocarcinoma, decidua and fibroblast cells in vitro (1989) (1)
Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system (2020) (1)
Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons (2012) (1)
Perineuronal net digestionwith chondroitinase restores memory inmice with tau pathology (2014) (1)
The spiral peripheral nerve interface: Design, fabrication and performance (2011) (1)
Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons (2008) (1)
Introduction: Repairing the damaged nervous system (1993) (1)
Refinement of Topographic Projections in the Rodent, Avian, Amphibian, and Fish Visual Systems (1993) (1)
Adaptation of tape removal test for measurement of sensitivity in perineal area of rat (2019) (1)
Influence of different extracellular matrix components on the expression of integrins and regeneration of adult retinal ganglion cells (2015) (1)
Axotomy and mechanical damage (2002) (1)
Inhibition of Semaphorin-3A promotes ocular dominance plasticity in the adult rat visual cortex (2018) (1)
Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program (2021) (1)
Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters (2020) (1)
Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters (2023) (1)
Microglia and Chondroitin Sulphate Proteoglycans Prevent the Migration and Integration of Retinal Stem Cells Into Degenerated Retina (2008) (0)
Immunochemical analysis of the integrin expression in retinal pigment epithelial cells (2020) (0)
Textbook of Neural Repair and Rehabilitation: The role of extracellular matrix in plasticity in the spinal cord (2014) (0)
11th International Symposium on Neural Regeneration (2006) (0)
Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts (2018) (0)
The perineuronal net and the control of CNS plasticity (2012) (0)
The role of proteoglycans in regeneration and plasticity (2004) (0)
The role of the extracellular matrix in the control of axon regeneration and plasticity (2007) (0)
Increasing the regenerative ability of axons (2011) (0)
Development of photosensitive polyimide as interfaces for repair of damage to nervous system (2008) (0)
Combination treatment with chondroitinase ABC in spinal cord injury—breaking the barrier (2013) (0)
Book Reviews (2003) (0)
Mechanically compliant implants as a strategy to decrease foreign body reaction to nerve interfaces (2019) (0)
Primary neuronal transplantation (2002) (0)
Restoring the pattern of perineuronal net sulphation corrects age-related memory loss (2020) (0)
Manuscript title Can Non-human Primate Experiments Expedite Translation of Potential Reparative Interventions After a Spinal Cord Injury in Humans ? Author list (2006) (0)
Microchannel electrode interfaces to assess bladder afferent activity (2011) (0)
Erratum: A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo (2012) (0)
1 1 Regulation of CNS plasticity through the extracellular matrix 2 3 (2020) (0)
The treatment of Spinal Cord Injury: past, present and future (2012) (0)
Chew Injury in Rat A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord (2013) (0)
Spinal Cord Injury (2005) (0)
Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury (2019) (0)
The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury (2019) (0)
Inflammation and demyelination (2002) (0)
Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy (2016) (0)
Foreign body reaction is triggered in vivo by cellular mechanosensing of implants stiffer than host tissue (2022) (0)
Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex (2019) (0)
Introduction. The regenerating brain (2006) (0)
InhibitingGlycosaminoglycanChainPolymerization DecreasestheInhibitoryActivityofAstrocyte-Derived ChondroitinSulfateProteoglycans (2007) (0)
Polymeric micro-channel electrodes for improved recording in peripheral nerve implant (2008) (0)
Compliant Multi-electrode Micro-channel Array for Recording Afferent Nerve Activity (2012) (0)
Geoffrey Raisman. 28 June 1939—27 January 2017 (2018) (0)
A Comparative Study of Preparation Techniques for Improving the Viability of Striatal Grafts Using Vital Stains, in Vitro Cultures, and in Vivo Grafts (1996) (0)
Substrate Specificity and Biochemical Characteristics of an Engineered Mammalian Chondroitinase ABC (2021) (0)
Short Communication Expression of Akt and MAPK in the Normal and Regenerating Peripheral Nerves and Their Dorsal Root Ganglia (2009) (0)
Treatment of injuries to the central nervous system (2003) (0)
Integrin Activation Increases RPE Adhesion To Bruch’s Membrane Components And Overcomes Tenascin-C-mediated Failure Of Adhesion In The Rat (2011) (0)
Cell-substrate interactions (2010) (0)
Decision letter: Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulfate production (2019) (0)
Control of inflammation (2002) (0)
Control of cell shape , neurite outgrowth and 1 migration by a novel Nogo-A / HSPG interaction 2 3 (2017) (0)
Spinal Cord Regeneration after Injury: Bridging by Schwann Cells and Bioimplants (2009) (0)
Edinburgh Explorer PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS (2020) (0)
Mechanisms of intermittent hypoxia-induced functional recovery after spinal cord injury (2014) (0)
The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult? (2019) (0)
Failure of CNS regeneration (2002) (0)
Rodent Brains MotifsNets via Chondroitin Sulfate Type E Semaphorin 3 A Binds to the Perineuronal Glycobiology and Extracellular Matrices : (2013) (0)
Exclusion of integrins from CNS axons is regulated by the axon initial segment and Arf6 activation. (2015) (0)
The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function (2019) (0)
Author response: Selective rab11 transport and the intrinsic regenerative ability of CNS axons (2017) (0)
Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries (2020) (0)

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