Jan-Åke Gustafsson
Swedish biochemist
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Biology
Why Is Jan-Åke Gustafsson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jan-Åke Gustafsson is a Swedish scientist and professor in Biology, Biochemistry and Medical Nutrition. When he decided to move to Houston, Texas, USA, in 2008, the State of Texas decided to give a major US $5.5 million research grant to the University of Houston, enabling the establishment of the Center of Nuclear Receptors and Cell Signaling under the leadership of Jan-Åke Gustafsson. The grant was announced at a February 5, 2009, press conference by Rick Perry, Governor of Texas and running for the Republican nomination for President of the United States in the 2012 presidential election.
Jan-Åke Gustafsson's Published Works
Published Works
- Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. (1998) (1910)
- Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. (1988) (319)
- Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor (1993) (198)
- The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein. (1990) (178)
- Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation (1994) (177)
- The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation (1991) (171)
- Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system (1994) (164)
- Definition of a novel ligand binding domain of a nuclear bHLH receptor: co‐localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor. (1993) (157)
- Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state (1988) (155)
- RECOMMENDED DIETARY ALLOWANCES FOR EUROPE (1989) (147)
- A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor (1994) (137)
- Morphometrical analysis of the distribution of corticotrophin releasing factor, glucocorticoid receptor and phenylethanolamine-N-methyltransferase immunoreactive structures in the paraventricular hypothalamic nucleus of the rat (1985) (124)
- Distinct roles of the molecular chaperone hsp90 in modulating dioxin receptor function via the basic helix-loop-helix and PAS domains (1995) (123)
- Heat shock protein hsp90 regulates dioxin receptor function in vivo. (1995) (121)
- Immunocytochemical studies on the localization of glucocorticoid receptor immunoreactive nerve cells in the lower brain stem and spinal cord of the male rat using a monoclonal antibody against rat liver glucocorticoid receptor (1985) (113)
- Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERα/ERβ ratio (2008) (98)
- High level expression of functional full length and truncated glucocorticoid receptor in Chinese hamster ovary cells. Demonstration of ligand-induced down-regulation of expressed receptor mRNA and protein. (1991) (95)
- Central peptidergic neurons as targets for glucocorticoid action. Evidence for the presence of glucocorticoid receptor immunoreactivity in various types of classes of peptidergic neurons (1991) (84)
- The dioxin and peroxisome proliferator-activated receptors: nuclear receptors in search of endogenous ligands. (1992) (80)
- Agonistic and antagonistic effects of alpha-naphthoflavone on dioxin receptor function. Role of the basic region helix-loop-helix dioxin receptor partner factor Arnt. (1994) (75)
- The receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse hepatoma cell line Hepa 1c1c7. A comparison with the glucocorticoid receptor and the mouse and rat hepatic dioxin receptors. (1987) (68)
- Rat 17 beta-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene. (1996) (66)
- Purification of the DNA binding form of dioxin receptor. Role of the Arnt cofactor in regulation of dioxin receptor function. (1994) (55)
- Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes. (1997) (55)
- A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin. (1988) (54)
- Regulation of human dioxin receptor function by indolocarbazoles, receptor ligands of dietary origin. (1994) (46)
- Activation of the dioxin and glucocorticoid receptors to a DNA binding state under cell-free conditions. (1990) (37)
- The Chitinase Gene of the Silkworm, Bombyx mori, Contains a Novel Tc-like Transposable Element* (2000) (29)
- Increased efficiency in screening large numbers of cDNA fragments generated by differential display. (1997) (29)
- Identification of target cells for the genomic effects of estrogens in bone. (2007) (29)
- 4-hydroxytamoxifen trans-represses nuclear factor-kappa B activity in human osteoblastic U2-OS cells through estrogen receptor (ER)alpha, and not through ER beta. (2001) (28)
- Metabolism of the dietary carcinogen TRP-P-1 in rats. (1986) (26)
- Cross-talk between steroids and NF-kappa B: what language? (1998) (26)
- The dioxin receptor: a comparison with the glucocorticoid receptor. (1988) (20)
- Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor (1991) (19)
- UKCCCR guidelines for the use of cell lines in cancer research (1999) (15)
- Ligands for orphan receptors? (1996) (14)
- DNA adduct formation of 14 heterocyclic aromatic amines in mouse tissue after oral administration and characterization of the DNA adduct formed by 2-amino-9H-pyrido[2,3-b]indole (AαC), analysed by 32 P-HPLC (2004) (12)
- Influence of pituitary and adrenocortical hormones on prostatic secretion protein, a major protein in rat prostate (1982) (10)
- Nuclear factor-kappa B repression in antiinflammation and immunosuppression by glucocorticoids. (1997) (8)
- The dioxin receptor: characterization of its DNA-binding properties. (1988) (8)
- A method for characterization of endogenous ligands to orphan receptors belonging to the steroid hormone receptor superfamily--isolation of progesterone from pregnancy plasma using progesterone receptor ligand-binding domain. (1992) (7)
- Structural differences between the glucocorticoid, dioxin and oxysterol receptors from rat liver cytosol. (1989) (6)
- UEG Week 2016 Poster Presentations (2016) (4)
- Assignment1 of estrogen receptor β (Esr2) to rat chromosome band 6q24 and (Estrb) to mouse chromosome band 12D1–D3 by in situ hybridization (1999) (2)
- Endocrine disruptors targeting ER b function (2010) (1)
- Xeno-estrogens: impact on the fetus and test system development (2000) (0)
- Subject Index Vol. 86, 1999 (1999) (0)
- P2-306: Activation of both LXRα and LXRβ is required for TO901317-mediated lowering of Aβ42: implications for the development of Alzheimer's therapeutics (2008) (0)
- Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses (2023) (0)
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